Ruxandra Covacu

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: EMBO REPORTS. 2023;24(1):e54944

The bromodomain protein TRIM28 controls the balance between growth and invasiveness in melanoma

Nyberg WA; Velasquez-Pulgarin DA; He T; Sjostrand M; Pelle L; Covacu R; Espinosa A
Journal article: NATURE. 2022;611(7937):801-809

Identification of environmental factors that promote intestinal inflammation.

Sanmarco LM; Chao C-C; Wang Y-C; Kenison JE; Li Z; Rone JM; Rejano-Gordillo CM; Polonio CM; Gutierrez-Vazquez C; Piester G; Plasencia A; Li L; Giovannoni F; Lee H-G; Faust Akl C; Wheeler MA; Mascanfroni I; Jaronen M; Alsuwailm M; Hewson P; Yeste A; Andersen BM; Franks DG; Huang C-J; Ekwudo M; Tjon EC; Rothhammer V; Takenaka M; de Lima KA; Linnerbauer M; Guo L; Covacu R; Queva H; Fonseca-Castro PH; Bladi MA; Cox LM; Hodgetts KJ; Hahn ME; Mildner A; Korzenik J; Hauser R; Snapper SB; Quintana FJ
Article: EPIGENETICS. 2022;17(11):1311-1330

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients

Kular L; Ewing E; Needhamsen M; Kakhki MP; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Article: IMMUNOLOGY. 2020;159(3):335-343

TRIM21 controls Toll-like receptor 2 responses in bone-marrow-derived macrophages

Sjoestrand M; Carow B; Nyberg WA; Covacu R; Rottenberg ME; Espinosa A
Article: JOURNAL OF NEUROIMMUNOLOGY. 2019;331:4-10

Endogenous spinal cord stem cells in multiple sclerosis and its animal model

Covacu R; Brundin L
Article: STEM CELL REPORTS. 2019;12(5):950-966

Adult Neural Progenitor Cells Transplanted into Spinal Cord Injury Differentiate into Oligodendrocytes, Enhance Myelination, and Contribute to Recovery

Sankavaram SR; Hakim R; Covacu R; Frostell A; Neumann S; Svensson M; Brundin L
Article: STEM CELL RESEARCH & THERAPY. 2019;10(1):115

Mesenchymal stem cells transplanted into spinal cord injury adopt immune cell-like characteristics

Hakim R; Covacu R; Zachariadis V; Frostell A; Sankavaram SR; Brundin L; Svensson M
Article: JOURNAL OF NEUROIMMUNOLOGY. 2019;328:5-19

Syngeneic, in contrast to allogeneic, mesenchymal stem cells have superior therapeutic potential following spinal cord injury

Hakim R; Covacu R; Zachariadis V; Frostell A; Sankavaram S; Svensson M; Brundin L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49(2):313-322

miR-31 regulates energy metabolism and is suppressed in Tcells from patients with Sjogren's syndrome

Johansson A; Nyberg WA; Sjostrand M; Moruzzi N; Bergman P; Khademi M; Andersson M; Piehl F; Berggren P-O; Covacu R; Jagodic M; Espinosa A
Article: CELL. 2019;176(3):581-596.e18

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

Wheeler MA; Jaronen M; Covacu R; Zandee SEJ; Scalisi G; Rothhammer V; Tjon EC; Chao C-C; Kenison JE; Blain M; Rao VTS; Hewson P; Barroso A; Gutierrez-Vazquez C; Prat A; Antel JP; Hauser R; Quintana FJ
Article: CELL REPORTS. 2016;14(11):2733-2744

System-wide Analysis of the T Cell Response.

Covacu R; Philip H; Jaronen M; Almeida J; Kenison JE; Darko S; Chao C-C; Yaari G; Louzoun Y; Carmel L; Douek DC; Efroni S; Quintana FJ
Article: JOURNAL OF NEUROIMMUNOLOGY. 2015;288:47-55

Long-distance effects of inflammation on differentiation of adult spinal cord neural stem/progenitor cells

Arvidsson L; Covacu R; Estrada CP; Sankavaram SR; Svensson M; Brundin L
Article: STEM CELLS AND DEVELOPMENT. 2014;23(19):2311-2327

Oxidative Stress Increases Neurogenesis and Oligodendrogenesis in Adult Neural Progenitor Cells

Estrada CP; Covacu R; Sankavaram SR; Svensson M; Brundin L
Article: STEM CELLS. 2014;32(9):2539-2549

Nitric Oxide-Induced Neuronal to Glial Lineage Fate-Change Depends on NRSF/REST Function in Neural Progenitor Cells

Bergsland M; Covacu R; Estrada CP; Svensson M; Brundin L
Article: JOURNAL OF NEUROSCIENCE. 2014;34(35):11571-11582

Change of Fate Commitment in Adult Neural Progenitor Cells Subjected to Chronic Inflammation

Covacu R; Estrada CP; Arvidsson L; Svensson M; Brundin L
Article: PLOS ONE. 2012;7(7):e39794

Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats

Adzemovic MZ; Ockinger J; Zeitelhofer M; Hochmeister S; Beyeen AD; Paulson A; Gillett A; Hedreul MT; Covacu R; Lassmann H; Olsson T; Jagodic M
Article: JOURNAL OF IMMUNOLOGY. 2009;182(11):6889-6895

TLR Activation Induces TNF-α Production from Adult Neural Stem/Progenitor Cells

Covacu R; Arvidsson L; Andersson A; Khademi M; Erlandsson-Harris H; Harris RA; Svensson MA; Olsson T; Brundin L
Article: EXPERIMENTAL CELL RESEARCH. 2008;314(20):3605-3613

The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide

Espinosa A; Oke V; Elfving A; Nyberg F; Covacu R; Wahren-Herlenius M
Article: STEM CELLS. 2006;24(12):2792-2800

Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis

Covacu R; Danilov AI; Rasmussen BS; Hallen K; Moe MC; Lobell A; Johansson CB; Svensson MA; Olsson T; Brundin L
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(2):394-400

Neurogenesis in the adult spinal cord in an experimental model of multiple sclerosis

Danilov AI; Covacu R; Moe MC; Langmoen IA; Johansson CB; Olsson T; Brundin L

Alla övriga publikationer

Preprint: BIORXIV. 2024

ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells

Neumann S; Thelin EP; Sankavaram SR; Persson S; Fonseca L; Moruzzi N; Iacobaeus E; Bergsland M; Popova E; Bader M; Svensson M; Espinosa A; Covacu R; Brundin L
Preprint: MEDRXIV. 2021

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients

Kular L; Ewing E; Needhamsen M; Kakhki MP; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Preprint: BIORXIV. 2019

Melanoma plasticity is controlled by a TRIM28-JUNB mediated switch

Nyberg W; He T; Sjöstrand M; Velasquez-Pulgarin D; Pellé L; Covacu R; Espinosa A
Review: NEUROSCIENTIST. 2017;23(1):27-39

Effects of Neuroinflammation on Neural Stem Cells

Covacu R; Brundin L
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):338

Histocompatibility of mouse bone marrow-derived mesenchymal stem cells transplanted into experimental spinal cord injury causes polarization of microglia towards the M2 phenotype and improved functional recovery

Hakim R; Neumann S; Frostell A; Sankavaram S; Covacu R; Brundin L; Svensson M
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):261

Effects of reactive oxygen species/reactive nitrogen species on neural stem cell fate

Neumann S; Covacu R; Brundin L
Review: JOURNAL OF NEUROIMMUNOLOGY. 2012;248(1-2):53-57

Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis.

Quintana FJ; Yeste A; Weiner HL; Covacu R
Review: JOURNAL OF LEUKOCYTE BIOLOGY. 2008;84(5):1248-1255

Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis

Andersson A; Covacu R; Sunnemark D; Danilov AI; Dal Bianco A; Khademi M; Wallstrom E; Lobell A; Brundin L; Lassmann H; Harris RA
Thesis / dissertation: 2008

Adult neural stem cells in neuroinflammation

Covacu, Ruxandra
Conference publication: JOURNAL OF NEUROIMMUNOLOGY. 2006;178:268

Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis

Covacu R; Danilov AI; Rasmussen BS; Hallen K; Moe MC; Lobell A; Olsson T; Svensson MA; Brundin L
Conference publication: JOURNAL OF NEUROIMMUNOLOGY. 2004;154(1-2):204

Effects of nitric oxide on adult neural stem cells

Covacu R; Aguilar-Santelises M; Olsson T; Brundin L

Anställningar

Senior Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-2025

Examina och utbildning

MEDICINE DOKTORSEXAMEN, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2008

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

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