Quirin Hammer

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Article: PLOS PATHOGENS. 2024;20(12):e1012755
Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness
Bilev E; Wild N; Momayyezi P; Sala BM; Sun R; Sandalova T; Marquardt N; Ljunggren H-G; Achour A; Hammer Q
Article: GENES AND IMMUNITY. 2024;:1-5
The HLA-B-21 M/T dimorphism associates with disease severity in COVID-19
Strunz B; Momayyezi P; Bilev E; Muvva JR; Chen P; Bister J; Schaffer M; Akber M; Cornillet M; Horowitz A; Malmberg K-J; Rooyackers O; Aleman S; Ljunggren H-G; Bjorkstrom NK; Stralin K; Hammer Q; Berglin L; Bergsten H; Brighenti S; Brownlie D; Buggert M; Butrym M; Chambers BJ; Cuapio A; Lozano ID; Dillner L; Djarv T; Dzidic M; Emgard J; Eriksson LI; Flodstrom-Tullberg M; Glans H; Gorin J-B; Grip J; Haroun-Izquierdo A; Henriksson E; Hertwig L; Kalsum S; Kammann T; Klingstroem J; Kokkinou E; Kvedaraite E; Loreti MG; Lourda M; Maleki KT; Marquardt N; Martensson J; Maucourant C; Michaelsson J; Mjosberg J; Moll K; Naucler P; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Persson BP; Radler L; Religa D; Ringqvist E; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Sohlberg E; Soini T; Soennerborg A; Svensson M; Tynell J; Unge C; Varnaite R; von Kries A; Wullimann D
Article: MED. 2024;:100521
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor.
Sætersmoen M; Kotchetkov IS; Torralba-Raga L; Mansilla-Soto J; Sohlberg E; Krokeide SZ; Hammer Q; Sadelain M; Malmberg K-J
Article: CELL STEM CELL. 2024;31(9):1376-1386.e8
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
Hammer Q; Perica K; Mbofung RM; van Ooijen H; Martin KE; Momayyezi P; Varady E; Pan Y; Jelcic M; Groff B; Abujarour R; Krokeide SZ; Lee T; Williams A; Goodridge JP; Valamehr B; Onfelt B; Sadelain M; Malmberg K-J
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2023;114(5):507-512
NK cells in COVID-19-from disease to vaccination
Hammer Q; Cuapio A; Bister J; Bjoerkstroem NK; Ljunggren H-G
Article: BLOOD ADVANCES. 2023;7(16):4492-4504
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
Philippon C; Tao S; Clement D; Haroun-Izquierdo A; Kichula KM; Netskar H; Brandt L; Oei VS; Kanaya M; Lanuza PM; Schaffer M; Goodridge JP; Horowitz A; Zhu F; Hammer Q; Sohlberg E; Majhi RK; Kveberg L; Onfelt B; Norman PJ; Malmberg K-J
Article: CURRENT PROTOCOLS. 2022;2(11):e613
Small Interfering RNA Delivery Into Primary Human Natural Killer Cells for Functional Gene Analyses
Momayyezi P; Malmberg K-J; Hammer Q
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577
Adaptive single-KIR⁺NKG2C⁺ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
Haroun-Izquierdo A; Vincenti M; Netskar H; van Ooijen H; Zhang B; Bendzick L; Kanaya M; Momayyezi P; Li S; Wiiger MT; Hoel HJ; Krokeide SZ; Kremer V; Tjonnfjord G; Berggren S; Wikstroem K; Blomberg P; Alici E; Felices M; oenfelt B; Hoeglund P; Valamehr B; Ljunggren H-G; Bjoerklund A; Hammer Q; Kveberg L; Cichocki F; Miller JS; Malmberg K-J; Sohlberg E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(7):1190-1193
An optimized platform for efficient siRNA delivery into human NK cells
Palacios D; Momayyezi P; Huhn O; Ask EH; Dunst J; Malmberg K-J; Hammer Q
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
The Karolinska KI/K COVID-19 immune atlas: An open resource for immunological research and educational purposes
Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
Article: CELL REPORTS. 2022;38(10):110503
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; Garcia M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Degenhardt F; Franke A; Spallotta F; Mori M; Michaelsson J; Bjorkstrom NK; Rueckert T; Romagnani C; Horowitz A; Klingstrom J; Ljunggren H-G; Malmberg K-J
Article: MOLECULAR MEDICINE. 2022;28(1):20
NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals
Cuapio A; Boulouis C; Filipovic I; Wullimann D; Kammann T; Parrot T; Chen P; Akber M; Gao Y; Hammer Q; Strunz B; Potti AP; Ballesteros OR; Lange J; Muvva JR; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; Osterborg A; Smith CIE; Bogdanovic G; Muschiol S; Hellgren F; Lore K; Sobkowiak MJ; Gabarrini G; Healy K; Chen MS; Alici E; Bjorkstrom NK; Buggert M; Ljungman P; Sandberg JK; Aleman S; Ljunggren H-G
Article: MBIO. 2021;12(2):e02996-e02920
Extent of Cytomegalovirus Replication in the Human Host Depends on Variations of the HLA-E/UL40 Axis
Vietzen H; Rueckert T; Hartenberger S; Honsig C; Jaksch P; Geleff S; Hammer Q; Romagnani C; Segura-Wang M; Puchhammer-Stoeckl E
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2020;217(8):e20190133
NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells
Babic M; Dimitropoulos C; Hammer Q; Stehle C; Heinrich F; Sarsenbayeva A; Eisele A; Durek P; Mashreghi M-F; Lisnic B; Van Snick J; Lohning M; Fillatreau S; Withers DR; Gagliani N; Huber S; Flavell RA; Polic B; Romagnani C
Article: SCIENCE IMMUNOLOGY. 2020;5(49):eaba7918
TOX is expressed by exhausted and polyfunctional human effector memory CD8⁺ T cells
Sekine T; Perez-Potti A; Son N; Gorin J-B; Wu VH; Gostick E; Llewellyn-Lacey S; Hammer Q; Falck-Jones S; Vangeti S; Yu M; Smed-Sorensen A; Gaballa A; Uhlin M; Sandberg JK; Brander C; Nowak P; Goepfert PA; Price DA; Betts MR; Buggert M
Article: NATURE COMMUNICATIONS. 2019;10(1):514
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Goodridge JP; Jacobs B; Saetersmoen ML; Clement D; Hammer Q; Clancy T; Skarpen E; Brech A; Landskron J; Grimm C; Pfefferle A; Meza-Zepeda L; Lorenz S; Wiiger MT; Louch WE; Ask EH; Liu LL; Oei VYS; Kjallquist U; Linnarsson S; Patel S; Tasken K; Stenmark H; Malmberg K-J
Article: SCIENCE IMMUNOLOGY. 2018;3(29):eaat9781
Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets
Wu C; Espinoza DA; Koelle SJ; Yang D; Truitt L; Schlums H; Lafont BA; Davidson-Moncada JK; Lu R; Kaur A; Hammer Q; Li B; Panch S; Allan DA; Donahue RE; Childs RW; Romagnani C; Bryceson YT; Dunbar CE
Article: NATURE IMMUNOLOGY. 2018;19(5):453-463
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Hammer Q; Rueckert T; Borst EM; Dunst J; Haubner A; Durek P; Heinrich F; Gasparoni G; Babic M; Tomic A; Pietra G; Nienen M; Blau IW; Hofmann J; Na I-K; Prinz I; Koenecke C; Hemmati P; Babel N; Arnold R; Walter J; Thurley K; Mashreghi M-F; Messerle M; Romagnani C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2017;47(10):1584-1797
Guidelines for the use of flow cytometry and cell sorting in immunological studies
Cossarizza A; Chang H-D; Radbruch A; Akdis M; Andrae I; Annunziato F; Bacher P; Barnaba V; Battistini L; Bauer WM; Baumgart S; Becher B; Beisker W; Berek C; Blanco A; Borsellino G; Boulais PE; Brinkman RR; Buescher M; Busch DH; Bushnell TP; Cao X; Cavani A; Chattopadhyay PK; Cheng Q; Chow S; Clerici M; Cooke A; Cosma A; Cosmi L; Cumano A; Dang VD; Davies D; De Biasi S; Del Zotto G; Della Bella S; Dellabona P; Deniz G; Dessing M; Diefenbach A; Di Santo J; Dieli F; Dolf A; Donnenberg VS; Doerner T; Ehrhardt GRA; Endl E; Engel P; Engelhardt B; Esser C; Everts B; Dreher A; Falk CS; Fehniger TA; Filby A; Fillatreau S; Follo M; Foerster I; Foster J; Foulds GA; Frenette PS; Galbraith D; Garbi N; Dolores Garcia-Godoy M; Geginat J; Ghoreschi K; Gibellini L; Goettlinger C; Goodyear CS; Gori A; Grogan J; Gross M; Gruetzkau A; Grummitt D; Hahn J; Hammer Q; Hauser AE; Haviland DL; Hedley D; Herrera G; Herrmann M; Hiepe F; Holland T; Hombrink P; Houston JP; Hoyer BF; Huang B; Hunter CA; Iannone A; Jaeck H-M; Javega B; Jonjic S; Juelke K; Jung S; Kaiser T; Kalina T; Keller B; Khan S; Kienhoefer D; Kroneis T; Kunkel D; Kurts C; Kvistborg P; Lannigan J; Lantz O; Larbi A; LeibundGut-Landmann S; Leipold MD; Levings MK; Litwin V; Liu Y; Lohoff M; Lombardi G; Lopez L; Lovett-Racke A; Lubberts E; Ludewig B; Lugli E; Maecker HT; Martrus G; Matarese G; Maueroeder C; McGrath M; McInnes I; Mei HE; Melchers F; Melzer S; Mielenz D; Mills K; Mirrer D; Mjosberg J; Moore J; Moran B; Moretta A; Moretta L; Mosmann TR; Mueller S; Muller W; Munz C; Multhoff G; Munoz LE; Murphy KM; Nakayama T; Nasi M; Neudoerfl C; Nolan J; Nourshargh S; O'Connor J-E; Ouyang W; Oxenius A; Palankar R; Panse I; Peterson P; Peth C; Petriz J; Philips D; Pickl W; Piconese S; Pinti M; Pockley AG; Podolska MJ; Pucillo C; Quataert SA; Radstake TRDJ; Rajwa B; Rebhahn JA; Recktenwald D; Remmerswaal EBM; Rezvani K; Rico LG; Robinson JP; Romagnani C; Rubartelli A; Ruckert B; Ruland J; Sakaguchi S; Sala-de-Oyanguren F; Samstag Y; Sanderson S; Sawitzki B; Scheffold A; Schiemann M; Schildberg F; Schimisky E; Schmid SA; Schmitt S; Schober K; Schueler T; Schulz AR; Schumacher T; Scotta C; Shankey TV; Shemer A; Simon A-K; Spidlen J; Stall AM; Stark R; Stehle C; Stein M; Steinmetz T; Stockinger H; Takahama Y; Tarnok A; Tian Z; Toldi G; Tornack J; Traggiai E; Trotter J; Ulrich H; van der Braber M; van Lier RAW; Veldhoen M; Vento-Asturias S; Vieira P; Voehringer D; Volk H-D; von Volkmann K; Waisman A; Walker R; Ward MD; Warnatz K; Warth S; Watson JV; Watzl C; Wegener L; Wiedemann A; Wienands J; Willimsky G; Wing J; Wurst P; Yu L; Yue A; Zhang Q; Zhao Y; Ziegler S; Zimmermann J
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1976
Adaptive Natural Killer Cells Integrate Interleukin-18 during Target-Cell Encounter
Hammer Q; Ruckert T; Dunst J; Romagnani C
Journal article: BLOOD. 2016;128(22):549
Clonal Expansion and Long-Term Persistence of Rhesus Macaque NK Cells with an Adaptive Phenotype
Wu C; Espinoza DA; Koelle SJ; Yang D; Schlums H; Davidson-Moncada JK; Lu R; Kaur A; Quirin H; Li B; Panch SR; Donahue RE; Childs RW; Romagnani C; Bryceson Y; Dunbar CE
Article: CELL REPORTS. 2016;15(5):1088-1099
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Liu LL; Landskron J; Ask EH; Enqvist M; Sohlberg E; Traherne JA; Hammer Q; Goodridge JP; Larsson S; Jayaraman J; Oei VYS; Schaffer M; Tasken K; Ljunggren H-G; Romagnani C; Trowsdale J; Malmberg K-J; Beziat V
Article: ONCOIMMUNOLOGY. 2016;5(9):e1219009
Adoptively transferred natural killer cells maintain long-term antitumor activity by epigenetic imprinting and CD4⁺ T cell help
Ni J; Hoelsken O; Miller M; Hammer Q; Luetke-Eversloh M; Romagnani C; Cerwenka A
Article: PLOS PATHOGENS. 2014;10(10):e1004441
Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2C^hi Natural Killer Cells
Luetke-Eversloh M; Hammer Q; Durek P; Nordstroem K; Gasparoni G; Pink M; Hamann A; Walter J; Chang H-D; Dong J; Romagnani C
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Alla övriga publikationer

Book chapter: NATURAL KILLER CELLS. 2025;p. 1-21
Navigating the Unknown: Open Questions Surrounding Natural Killer Cell Responses to SARS-CoV-2
Hammer Q
Preprint: BIORXIV. 2024
Human NK cell responses to the SARS-CoV-2 Spike269-277 peptide YLQPRTFLL
Bilev E; Schiele S; Foglietta B; Ljunggren H-G; Hammer Q
Review: NATURE REVIEWS IMMUNOLOGY. 2024;24(9):680-693
Engineering immune-evasive allogeneic cellular immunotherapies
Martin KE; Hammer Q; Perica K; Sadelain M; Malmberg K-J
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2023;53(11):e2350465
Viral escape from NK-cell-mediated immunosurveillance: A lesson for cancer immunotherapy?
Momayyezi P; Bilev E; Ljunggren H-G; Hammer Q
Review: SEMINARS IN IMMUNOPATHOLOGY. 2019;41(1):59-68
Off-the-shelf cell therapy with induced pluripotent stem cell-derived natural killer cells
Saetersmoen ML; Hammer Q; Valamehr B; Kaufman DS; Malmberg K-J
Review: NATURE IMMUNOLOGY. 2018;19(8):800-808
Natural killer cell specificity for viral infections
Hammer Q; Rueckert T; Romagnani C
Editorial comment: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2017;91A(10):997-1000
OMIP-039: Detection and analysis of human adaptive NKG2C⁺ natural killer cells
Hammer Q; Romagnani C
Review: ADVANCES IN IMMUNOLOGY, VOL 150. 2017;133:171-207
About Training and Memory: NK-Cell Adaptation to Viral Infections
Hammer Q; Romagnani C

Forskningsbidrag

Decoding viral evolution in real time and assessing its impact on host innate immune responses
Swedish Research Council
1 January 2025 - 31 December 2028
KI Foundation for Virus Research 2021-2022
Clas Groschinskys Minnesfond 2021-2022
Forskar-ST 2021-2025
Region Stockholm
KI Foundation for Virus Research 2022-2023
Clas Groschinskys Minnesfond 2022-2023
KI Foundations 2022-2024
Jonas Söderquist Prize 2022
Åke Wibergs Stiftelse 2022-2024
KI Foundation for Virus Research 2023-2024
Felix Mindus Foundation 2023-2024
Stiftelsen Tornspiran 2023-2024
Dr Åke Olsson Foundation 2024-2025
KI Foundation for Virus Research 2024-2025
Jeanssons Stiftelser 2024-2026
Åke Wibergs Stiftelse 2024-2026
Petrus och Augusta Hedlunds Stiftelse 2021-2022
Stiftelsen Lars Hiertas Minne 2021-2022
Stiftelsen Tornspiran 2021-2023
Petrus och Augusta Hedlunds Stiftelse 2022-2023
Stiftelsen Lars Hiertas Minne 2023-2024
KI Foundations 2024-2026
Magnus Bergvall Stiftelse 2024-2025
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