Quirin Hammer

Quirin Hammer

Assistant Professor
Visiting address: Alfred Nobels allé 8, plan 7, 14152 HUDDINGE
Postal address: H7 Medicin, Huddinge, H7 CIM Ljunggren Hammer, 171 77 Stockholm

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Grants

  • Swedish Research Council
    1 January 2025 - 31 December 2028
    It is a natural occurrence that viruses and humans co-exist. Although the acute phase of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is behind us, the virus continues to evolve. This ongoing evolution poses a high risk for the emergence of variants, which undermine existing immunity. While considerable knowledge exists regarding antibody responses and T cells reactivity, the contribution of innate factors in protecting us against SARS-CoV-2 remains relatively unexplored. Moreover, it is still unknown whether SARS-CoV-2 evolves to escape from such innate immunity.The proposed project addresses this knowledge gap by decoding the interplay of SARS-CoV-2 evolution with host innate immunity and the consequences thereof on infection outcomes in patients. To this end, we will delineate whether mutations in emerging variants impact on recognition by innate natural killer (NK) cells. We will monitor the co-evolution of SARS-CoV-2 with NK cells in real time by leveraging computational methods and global databases. Finally, we seek to understand how this interplay influences infection outcomes in patients, potentially paving the way for precision medicine interventions.Collectively, successful implementation of the project will provide interdisciplinary insights that deepen our understanding of viral evolution and its impact on host innate immune responses. This may have important implications for patients and provide valuable insights for future pandemics.
  • KI Foundation for Virus Research 2021-2022
  • Petrus och Augusta Hedlunds Stiftelse 2021-2022
  • Clas Groschinskys Minnesfond 2021-2022
  • Stiftelsen Lars Hiertas Minne 2021-2022
  • Stiftelsen Tornspiran 2021-2023
  • Forskar-ST 2021-2025
    Region Stockholm
  • KI Foundation for Virus Research 2022-2023
  • Petrus och Augusta Hedlunds Stiftelse 2022-2023
  • Clas Groschinskys Minnesfond 2022-2023
  • KI Foundations 2022-2024
  • Åke Wibergs Stiftelse 2022-2024
  • KI Foundation for Virus Research 2023-2024
  • Stiftelsen Lars Hiertas Minne 2023-2024
  • Felix Mindus Foundation 2023-2024
  • Stiftelsen Tornspiran 2023-2024
  • KI Foundation for Virus Research 2024-2025
  • Jeanssons Stiftelser 2024-2026
  • KI Foundations 2024-2026
  • Åke Wibergs Stiftelse 2024-2026
  • Magnus Bergvall Stiftelse 2024-2025
  • Show more

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