Petter Höglund

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Om mig

Prefekt på institutionen för medicin, Huddinge och gruppledare för Immunological tolerance and transfusion immunology vid HERM, KI.

Utnämnd till professor i basal immunologi, särskilt kliniskt tillämpad cellterapi och transplantation, vid Karolinska Institutet 2011. Läs mer på min engelska profilsida

Artiklar

Article: HLA. 2024;103(3):e15429

High-resolution HLA genotyping identifies risk alleles in both class I and II for primary autoimmune neutropenia in early childhood in a Danish cohort

Klove-Mogensen K; Haunstrup TM; Masmas TN; Glenthoj A; Hoglund P; Hasle H; Nielsen KR; Steffensen R
Article: BLOOD ADVANCES. 2024;8(3):571-580

Clinical and immunological features in ACKR1/DARC-associated neutropenia

Palmblad J; Sohlberg E; Nilsson CC; Lindqvist H; Deneberg S; Ratcliffe P; Meinke S; Mortberg A; Klimkowska M; Hoglund P
Journal article: CLINICAL IMMUNOLOGY COMMUNICATIONS. 2023;3:31-36

HNA specificity and association to HLA-DRB1 and -DQB1 in patients with autoimmune neutropenia of early childhood

Kløve-Mogensen K; Steffensen R; Nielsen HL; Masmas TN; Glenthøj A; Jensen CF; Haunstrup TM; Ratcliffe P; Höglund P; Hasle H; Nielsen KR
Article: TRANSFUSION. 2023;63(11):2040-2051

Red blood cell alloimmunization in myelodysplastic syndromes: Associations with sex, DAT-positivity, and increased transfusion needs

Ryden J; Clements M; Wikman A; Hellstrom-Lindberg E; Edgren G; Hoglund P
Article: SCIENCE SIGNALING. 2023;16(780):eabq0752

SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency

Schmied L; Luu TT; Sondergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Casoni GP; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Hoglund P
Article: HEMASPHERE. 2023;7(4):e872

The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Action

Fioredda F; Skokowa J; Tamary H; Spanoudakis M; Farruggia P; Almeida A; Guardo D; Hoglund P; Newburger PE; Palmblad J; Touw IP; Zeidler C; Warren AJ; Dale DC; Welte K; Dufour C; Papadaki HA
Article: INTERNATIONAL JOURNAL OF IMMUNOGENETICS. 2023;50(2):65-74

Genetic variations in low-to-medium-affinity Fcγ receptors and autoimmune neutropenia in early childhood in a Danish cohort

Klove-Mogensen K; Steffensen R; Masmas TN; Glenthoj A; Jensen CF; Haunstrup TM; Ratcliffe P; Hoglund P; Hasle H; Nielsen KR
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577

Adaptive single-KIR⁺NKG2C⁺ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia

Haroun-Izquierdo A; Vincenti M; Netskar H; van Ooijen H; Zhang B; Bendzick L; Kanaya M; Momayyezi P; Li S; Wiiger MT; Hoel HJ; Krokeide SZ; Kremer V; Tjonnfjord G; Berggren S; Wikstroem K; Blomberg P; Alici E; Felices M; oenfelt B; Hoeglund P; Valamehr B; Ljunggren H-G; Bjoerklund A; Hammer Q; Kveberg L; Cichocki F; Miller JS; Malmberg K-J; Sohlberg E
Article: TRANSFUSION. 2022;62(8):1636-1642

ABO, secretor, and Lewis carbohydrate histo-blood groups are associated with autoimmune neutropenia of early childhood in Danish patients

Klove-Mogensen K; Steffensen R; Masmas TN; Glenthoj A; Haunstrup TM; Ratcliffe P; Hoglund P; Hasle H; Nielsen KR
Article: BLOOD. 2022;139(5):704-716

Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia

Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Netskar H; Lorenz S; Kanaya M; Kosugi-Kanaya M; Meinke S; Mortberg A; Hoglund P; Sundin M; Carlsson G; Palmblad J; Malmberg K-J
Article: FRONTIERS IN PUBLIC HEALTH. 2022;10:1073318

Cryopreserved platelets in bleeding management in remote hospitals: A clinical feasibility study in Sweden

Wikman A; Diedrich B; Bjorling K; Forsberg P-O; Harstad A-M; Henningsson R; Hoglund P; Skold H; ostman L; Sandgren P
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312

FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development

Luu TT; Sondergaard JN; Pena-Perez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers BJ; Achour A; Kutter C; Hoglund P; Mansson R; Kadri N
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):224-233

Platelet transfusion improves clot formation and platelet function in severely thrombocytopenic haematology patients

Karlstrom C; Gryfelt G; Schmied L; Meinke S; Hoglund P
Article: MALARIA JOURNAL. 2021;20(1):441

Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

Hedberg P; Sirel M; Moll K; Kiwuwa MS; Hoglund P; Ribacke U; Wahlgren M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1):e13037

The blood protein hCAP-18 in neutropenia: An 18-month experience of a new ELISA for clinical use

Mortberg A; Putsep K; Hoglund P
Article: LIFE SCIENCE ALLIANCE. 2021;4(4):e202000723

Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch

Luu TT; Schmied L; Nguyen N-A; Wiel C; Meinke S; Mohammad DK; Bergo M; Alici E; Kadri N; Ganesan S; Hoglund P
Article: TRANSFUSION. 2021;61(4):1222-1234

HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients

Mirlashari MR; Vetlesen A; Nissen-Meyer LSH; Naper C; Tjonnfjord GE; Njerve IU; Ezligini F; Landmark BF; Meinke S; Sandgren P; Hoglund P; Hetland G
Article: TRANSFUSION. 2021;61(2):464-473

Frequent platelet donation is associated with lymphopenia and risk of infections: A nationwide cohort study

Zhao J; Gabriel E; Norda R; Hoglund P; Baden L; Diedrich BA; Marits P; Enoksson SL; Gansner JM; Kaufman R; Dickman PW; Edgren G
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(6):e12997

Covid-19, SSI 50 years and Nobel: Three immunological reasons to remember 2020.

Höglund P; Ljunggren H-G; Jonsson R
Article: TRANSFUSION MEDICINE AND HEMOTHERAPY. 2020;47(5):385-395

Multicenter Study on Differential Human Neutrophil Antigen 2 Expression and Underlying Molecular Mechanisms

Flesch BK; Reil A; Nogues N; Canals C; Bugert P; Schulze TJ; Huiskes E; Porcelijn L; Hoglund P; Ratcliffe P; Schoenbacher M; Kerchrom H; Kellershohn J; Bayat B
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504

IL-15 and CD155 expression regulate LAT expression in murine DNAM1⁺ NK cells, enhancing their effectors functions

Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Hoglund P; Kadri N
Article: TRANSFUSION. 2019;59(3):945-952

HLA-selected platelets for platelet refractory patients with HLA antibodies: a single-center experience

Karlstrom C; Linjama T; Edgren G; Lauronen J; Wikman A; Hoglund P
Article: LEUKEMIA. 2019;33(2):522-527

Male sex and the pattern of recurrent myeloid mutations are strong independent predictors of blood transfusion intensity in patients with myelodysplastic syndromes

Ryden J; Edgren G; Karimi M; Walldin G; Tobiasson M; Wikman A; Hellstrom-Lindberg E; Hoglund P
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249

The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes

Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Le Blanc K; Kadri N; Hoglund P
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;88(6):e12731

Seminal immunologic discoveries with direct clinical implications: The 2018 Nobel Prize in Physiology or Medicine honours discoveries in cancer immunotherapy.

Ljunggren H-G; Jonsson R; Höglund P
Article: TRANSFUSION. 2018;58(11):2657-2668

Cryopreservation of buffy coat-derived platelet concentrates photochemically treated with amotosalen and UVA light

Meinke S; Wikman A; Gryfelt G; Hultenby K; Uhlin M; Hoeglund P; Sandgren P
Article: VOX SANGUINIS. 2018;113(8):779-786

Anti-D quantification in relation to anti-D titre, middle cerebral artery Doppler measurement and clinical outcome in RhD-immunized pregnancies

Wikman A; Jalkesten E; Ajne G; Hoeglund P; Mortberg A; Tiblad E
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224

Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes

Palma M; Krstic A; Perez LP; Bergloef A; Meinke S; Wang Q; Blomberg KEM; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; De Paepe A; Hoeglund P; Kimby E; OEsterborg A; Mansson R; Smith CIE
Article: THROMBOSIS RESEARCH. 2018;162:69-76

Adding to the complexity of fetal and neonatal alloimmune thrombocytopenia: Reduced fibrinogen binding in the presence of anti-HPA-1a antibody and hypo-responsive neonatal platelets

Refsum E; Meinke S; Gryfelt G; Wikman A; Hoglund P
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3173

Inhibitory Receptor Crosslinking Quantitatively Dampens Calcium Flux Induced by Activating Receptor Triggering in NK Cells

Ganesan S; Hoglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142

The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education

Ganesan S; Luu TT; Chambers BJ; Meinke S; Brodin P; Vivier E; Wetzel DM; Koleske AJ; Kadri N; Hoglund P
Article: NATURE COMMUNICATIONS. 2017;8(1):224

Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

Yougbare I; Tai W-S; Zdravic D; Oswald BE; Lang S; Zhu G; Leong-Poi H; Qu D; Yu L; Dunk C; Zhang J; Sled JG; Lye SJ; Brkic J; Peng C; Hoglund P; Croy BA; Adamson SL; Wen X-Y; Stewart DJ; Freedman J; Ni H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;85(6):417-424

TLR-Stimulated Eosinophils Mediate Recruitment and Activation of NK Cells In Vivo

O'Flaherty SM; Sutummaporn K; Haggtoft WL; Worrall AP; Rizzo M; Braniste V; Hoglund P; Kadri N; Chambers BJ
Article: NATURE COMMUNICATIONS. 2017;8:15627

Expression of CD226 is associated to but not required for NK cell education

Wagner AK; Kadri N; Snall J; Brodin P; Gilfillan S; Colonna M; Bernhardt GN; Hoglund P; Karre K; Chambers BJ
Journal article: ISBT SCIENCE SERIES. 2017;12(1):148-153

HLA‐stripped platelets: preclinical developments and clinical outlooks

Meinke S; Karlström C; Gryfelt G; Wikman A; Höglund P
Article: TRANSFUSION MEDICINE. 2017;27(1):43-51

Characterisation of maternal human leukocyte antigen class I antibodies in suspected foetal and neonatal alloimmune thrombocytopenia

Refsum E; Mortberg A; Dahl J; Meinke S; Auvinen M-K; Westgren M; Reilly M; Hoglund P; Wikman A
Article: VOX SANGUINIS. 2017;112(1):33-39

Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study

Gulliksson H; Meinke S; Ravizza A; Larsson L; Hoglund P
Article: SCIENTIFIC REPORTS. 2016;6:37996

Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+dendritic cells

Thuy TL; Ganesan S; Wagner AK; Sarhan D; Meinke S; Garbi N; Haemmerling G; Alici E; Karre K; Chambers BJ; Hoglund P; Kadri N
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769

In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation

Lakshmikanth T; Heuts F; Muvva SSVJR; Wallin RPA; Persson A-K; Fauriat C; Applequist SE; Ljunggren H-G; Hoglund P; Karre K; Svensson M; Juarez JG
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2016;434:9-15

Sensitive detection of platelet-specific antibodies with a modified MAIPA using biotinylated antibodies and streptavidin-coated beads

Mortberg A; Meinke S; Berg P; Killie MK; Kjeldsen-Kragh J; Jaras K; Refsum E; Hoglund P; Wikman A
Article: IMMUNOLOGY AND CELL BIOLOGY. 2016;94(2):177-184

Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice

Brauner H; Hall HT; Flodstrom-Tullberg M; Karre K; Hoglund P; Johansson S
Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123

Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response

Wagner AK; Wickstrom SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Hoglund P; Carbone E; Johansson MH; Karre K
Article: TRANSFUSION. 2016;56(2):370-382

Platelets made HLA deficient by acid treatment aggregate normally and escape destruction by complement and phagocytes in the presence of HLA antibodies

Meinke S; Sandgren P; Mortberg A; Karlstrom C; Kadri N; Wikman A; Hoglund P
Article: TRANSFUSION. 2014;54(3):602-612

Random aggregates in newly produced platelet units are associated with platelet activation and release of the immunomodulatory factors sCD40L and RANTES

Sandgren P; Meinke S; Eckert E; Douagi I; Wikman A; Hoglund P
Article: BLOOD TRANSFUSION. 2013;11(3):456-459

A severe haemolytic transfusion reaction caused by anti-Le^a active at 37°C

Hoglund P; Rosengren-Lindquist R; Wikman AT
Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65

Natural killer cell inhibitory receptor expression in humans and mice: a closer look

Sternberg-Simon M; Brodin P; Pickman Y; Onfelt B; Karre K; Malmberg K-J; Hoglund P; Mehr R
Article: ACTA DERMATO-VENEREOLOGICA. 2012;92(6):609-614

No Association between Infections, HLA Type and Other Transplant-related Factors and Risk of Cutaneous Squamous Cell Carcinoma in Solid Organ Transplant Recipients

Ingvar A; Smedby KE; Lindelof B; Fernberg P; Bellocco R; Tufveson G; Hoglund P; Adami J
Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226

Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets

Brodin P; Lakshmikanth T; Karre K; Hoglund P
Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2011;11(11):2472-2482

Time Trends in Risk and Risk Determinants of Non-Hodgkin Lymphoma in Solid Organ Transplant Recipients

Fernberg P; Edgren G; Adami J; Ingvar A; Bellocco R; Tufveson G; Hoglund P; Kinch A; Simard JF; Baecklund E; Lindelof B; Pawitan Y; Smedby KE
Article: BIOPHYSICAL JOURNAL. 2011;101(5):1257-1269

A Modified FCCS Procedure Applied to Ly49A-MHC Class I cis-Interaction Studies in Cell Membranes

Stromqvist J; Johansson S; Xu L; Ohsugi Y; Andersson K; Muto H; Kinjo M; Hoglund P; Widengren J
Article: JOURNAL OF IMMUNOLOGY. 2011;187(2):760-773

Simulations of the NK Cell Immune Synapse Reveal that Activation Thresholds Can Be Established by Inhibitory Receptors Acting Locally

Kaplan A; Kotzer S; Almeida CR; Kohen R; Halpert G; Salmon-Divon M; Koehler K; Hoeglund P; Davis DM; Mehr R
Article: PLOS ONE. 2010;5(10):e13174

Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice

Brodin P; Lakshmikanth T; Mehr R; Johansson MH; Duru AD; Achour A; Salmon-Divon M; Karre K; Hoglund P; Johansson S
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2010;25(8):2764-2771

Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma

Ingvar A; Smedby KE; Lindelof B; Fernberg P; Bellocco R; Tufveson G; Hoglund P; Adami J
Article: JOURNAL OF IMMUNOLOGY. 2010;184(5):2272-2280

Distinct Phenotype and Function of NK Cells in the Pancreas of Nonobese Diabetic Mice

Brauner H; Elemans M; Lemos S; Broberger C; Holmberg D; Flodstrom-Tullberg M; Karre K; Hoglund P
Article: JOURNAL OF AUTOIMMUNITY. 2010;34(1):66-72

AIRE deficiency leads to impaired iNKT cell development

Lindh E; Rosmaraki E; Berg L; Brauner H; Karlsson MCI; Peltonen L; Hoglund P; Winqvist O
Article: PLOS ONE. 2009;4(6):e6046

Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice

Johansson S; Salmon-Divon M; Johansson MH; Pickman Y; Brodin P; Karre K; Mehr R; Hoglund P
Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(5):1251-1263

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

Lakshmikanth T; Burke S; Ali TH; Kimpfler S; Ursini F; Ruggeri L; Capanni M; Umansky V; Paschen A; Sucker A; Pende D; Groh V; Biassoni R; Hoglund P; Kato M; Shibuya K; Schadendorf D; Anichini A; Ferrone S; Velardi A; Karre K; Shibuya A; Carbone E; Colucci F
Article: IMMUNITY. 2009;30(3):337-347

A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHIC Class I for Natural Killer Cell Education

Chalifour A; Scarpellino L; Back J; Brodin P; Devevre E; Gros F; Levy F; Leclercq G; Hoglund P; Beermann F; Held W
Article: BLOOD. 2009;113(11):2434-2441

The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

Brodin P; Lakshmikanth T; Johansson S; Karre K; Hoglund P
Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468

Distinct and Overlapping Patterns of Cytokine Regulation of Thymic and Bone Marrow-Derived NK Cell Development

Cheng M; Charoudeh HN; Brodin P; Tang Y; Lakshmikanth T; Hoglund P; Jacobsen SEW; Sitnicka E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937

Beyond licensing and disarming: A quantitative view on NK-cell education

Brodin P; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):3191-3199

Increased diabetes development and decreased function of CD4⁺ CD25⁺ Treg in the absence of a functional DAP12 adaptor protein

Hall HTL; Sjolin H; Brauner H; Tomasello E; Dalod M; Vivier E; Hoglund P
Article: MOLECULAR IMMUNOLOGY. 2008;45(11):3059-3064

TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation

Berglund JP; Mariotti-Ferrandiz E; Rosmaraki E; Hall H; Cazenave P-A; Six A; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2007;37(2):516-527

Quantifying the reduction in accessibility of the inhibitory NK cell receptor Ly49A caused by binding MHC class I proteins in cis

Andersson KE; Williams GS; Davis DM; Hoglund P
Article: JOURNAL OF IMMUNOLOGY. 2006;177(5):2908-2916

DAP12 signalling regulates plasmacytoid ddendritic cell homeostasis and down-modulates their function during viral infection

Sjolin H; Robbins SH; Bessou G; Hidmark A; Tomasello E; Johansson M; Hall H; Charifi F; Hedestam GBK; Biron CA; Karre K; Hoglund P; Vivier E; Dalod M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2006;36(2):264-266

Induced peripheral regulatory T cells:: The family grows larger

Höglund P
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;307(1-2):73-81

Impact of plastic adhesion in vitro on analysis of Th1 and Th2 cytokines and immune cell distribution from mice with multiple low-dose streptozotocin-induced diabetes

Thorvaldson L; Johansson SE; Höglund P; Sandler S
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2005;201(7):1145-1155

Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules

Johansson S; Johansson M; Rosmaraki E; Vahlne G; Mehr R; Salmon-Divon M; Lemonnier F; Kärre K; Höglund P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(48):16873-16878

Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells

Vanherberghen B; Andersson K; Carlin LM; Hoen ENMN; Williams GS; Höglund P; Davis DM
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(11):3091-3101

Reduced antigen concentration and costimulatory blockade increase IFN-γ secretion in naive CD8⁺ T cells

Hall HTL; Petrovic J; Höglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):134-142

Inhibition of the proteasome reduces transfer-induced diabetes in nonobese diabetic mice

Petrovic J; Hall H; Mehr R; Glas R; Höglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(6):1646-1653

Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo -: role of KARAP/DAP12-dependent and -independent pathways

Öberg L; Johansson S; Michaëlsson J; Tomasello E; Vivier E; Kärre K; Höglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(1):71-78

Low number of H-2D^d-negative haematopoietic cells in mixed bone marrow chimeras convey in vivo tolerance to H-2D^d-negative cells but fail to prevent resistance to H-2D^d-negative leukaemia

Johansson MH; Höglund P
Article: INTERNATIONAL IMMUNOLOGY. 2004;16(1):1-11

Broadly impaired NK cell function in nonobese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro

Johansson SE; Hall H; Björklund J; Höglund P
Article: IMMUNOLOGY. 2003;110(3):313-321

MHC-dependent and -independent modulation of endogenous Ly49 receptors on NK1.1⁺ T lymphocytes directed by T-cell receptor type

Sköld M; Stenström M; Sidobre S; Höglund P; Kronenberg M; Cardell S
Article: CANCER IMMUNITY. 2003;3:6

The uterine cervix--a new member of the family of immunologically exceptional sites?

Höglund P; Kärre K; Klein G
Journal article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2003;10(2-4):183-192

Models for natural killer cell repertoire formation.

Salmon-Divon M; Höglund P; Mehr R
Article: BULLETIN OF MATHEMATICAL BIOLOGY. 2003;65(2):199-218

Generation of the natural killer cell repertoire:: The sequential vs. the two-step selection model

Salmon-Divon M; Höglund P; Mehr R
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2001;194(10):1519-1530

Acquisition of external major histocompatibility complex class I molecules by natural killer cells expressing inhibitory Ly49 receptors

Sjöström A; Eriksson M; Cerboni C; Johansson MH; Sentman CL; Kärre K; Höglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(2):525-533

Differential effects on T cell and NK cell development by tissue-specific expression of H-2D^d transgene

Johansson MH; Bieberich C; Kåse-Sjöström A; Yoshioka T; Höglund E; Christy BA; Scangos G; Kärre K; Jay G; Höglund P
Article: INTERNATIONAL IMMUNOLOGY. 1999;11(8):1239-1246

Natural killing of MHC class I^- lymphoblasts by NK cells from long-term bone marrow culture requires effector cell expression of Ly49 receptors

Lindberg J; Martín-Fontecha A; Höglund P
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1999;189(2):331-339

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes.

Höglund P; Mintern J; Waltzinger C; Heath W; Benoist C; Mathis D
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(12):4198-4206

α1/α2 domains of H-2D^d, but not H-2L^d, induce "missing self" reactivity in vivo -: No effect of H-2L^d on protection against NK cells expressing the inhibitory receptor Ly49G2

Johansson MH; Höglund E; Nakamura MC; Ryan JC; Höglund P
Article: JOURNAL OF IMMUNOLOGY. 1998;161(11):6133-6138

External and internal calibration of the MHC class I-specific receptor Ly49A on murine natural killer cells

Kåse A; Johansson MH; Olsson-Alheim MY; Kårre A; Höglund P
Article: DIABETES. 1998;47(8):1207-1211

Interleukin-4 deficiency does not exacerbate disease in NOD mice.

Wang B; Gonzalez A; Höglund P; Katz JD; Benoist C; Mathis D
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1998;187(3):427-432

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes.

Lühder F; Höglund P; Allison JP; Benoist C; Mathis D
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(1):370-378

β2-Microglobulin-deficient NK cells show increased sensitivity to MHC class I-mediated inhibition, but self tolerance does not depend upon target cell expression of H-2K^b and D^b heavy chains

Höglund P; Glas R; Ménard C; Kåse A; Johansson MH; Franksson L; Lemmonier F; Kärre K
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1997;186(3):353-364

Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene

Johansson MH; Bieberich C; Jay G; Karre K; Hoglund P
Article: TRANSPLANTATION. 1997;63(1):119-123

Major histocompatibility complex class I-independent killing of xenogenic targets by rat allospecific natural killer cells

Torgersen KM; Salcedo M; Vaage JT; Naper C; Rolstad B; Ljunggren HG; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(1):342-345

Lack of F-1 anti-parental resistance in H-2(b/d) F-1 hybrids devoid of beta(2)-microglobulin

Hoglund P; OlssonAlheim MY; Johansson M; Karre K; Sentman CL
Article: CARCINOGENESIS. 1995;16(10):2515-2521

CHARACTERIZATION OF HUMAN BUCCAL EPITHELIAL-CELLS TRANSFECTED WITH THE SIMIAN-VIRUS-40 T-ANTIGEN GENE

KULKARNI PS; SUNDQVIST K; BETSHOLTZ C; HOGLUND P; WIMAN KG; ZHIVOTOVSKY B; BERTOLERO F; LIU Y; GRAFSTROM RC
Article: TRANSPLANTATION. 1995;60(3):281-286

NATURAL-KILLER-CELL INTERACTION WITH MURINE ALLOGENEIC MHC CLASS-I MOLECULES

SALCEDO M; HOGLUND P; LJUNGGREN HG
Article: MOLECULAR IMMUNOLOGY. 1995;32(11):789-794

ALTERED MHC CLASS-I PRESENTED PEPTIDE REPERTOIRE IS NOT SUFFICIENT TO INDUCE NK CELL-MEDIATED F-1-HYBRID RESISTANCE

SALCEDO M; HOGLUND P; ACHOUR A; THORPE CJ; LJUNGGREN HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(5):1286-1291

INHIBITION OF NATURAL-KILLER CELL-MEDIATED BONE-MARROW GRAFT-REJECTION BY ALLOGENEIC MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I, BUT NOT CLASS-II MOLECULES

OHLEN C; HOGLUND P; SENTMAN CL; CARBONE E; LJUNGGREN HG; KOLLER B; KARRE K
Article: CANCER RESEARCH. 1995;55(9):1911-1916

REJECTION OF TUMORS IN MICE WITH SEVERE COMBINED IMMUNODEFICIENCY SYNDROME DETERMINED BY THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I EXPRESSION ON THE GRAFT

GLAS R; WALDENSTROM M; HOGLUND P; KLEIN G; KARRE K; LJUNGGREN HG
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Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13347

Chlamydia pathogenesis in mice: Male immunity and the outcome of female infection

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(6):e13340

The prize of prizes: mRNA research paving the way for COVID-19 vaccine success wins the Nobel Prize in Physiology or Medicine 2023

Buggert M; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;97(6)

SSI 2023 in Turku: The 49th annual meeting of the Scandinavian Society for Immunology coming up

Hoglund P
Review: HEMASPHERE. 2023;7(1):e814

Autoimmune Neutropenias: Update on Clinical and Biological Features in Children and Adults

Fioredda F; Dufour C; Hoglund P; Papadaki HA; Palmblad J
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(6)

Nobel 2022: An extraordinary achievement relevant to immunity

Hoglund P; Ljunggren H-G; Jonsson R
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(5)

Antigen presentation in mucosal tissues: Dendritic cells and GP2

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(3)

Gender bias in complex autoimmune disorders: Clinically characterized cohorts pave the way for new knowledge

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(2)

SJI 50 years: Immunosurveillance in the brain and our highest impact factor ever

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13199

Resource article: A new category of SJI publications

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(6)

Two immunology happenings this June: Iceland hosts SSI 2022 and follicular T cells celebrate SJI 50 years

Hoglund P
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2022;97(6):E207-E210

Mutation in the TACI gene and autoimmune neutropenia: A case report

Bergman P; Broliden P-A; Ratcliffe P; Lourda M; Flesch B; Hoglund P; Palmblad J
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(5):e13173

Immunology according to Dembic: Preserving integrity is key

Corthay A; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13165

Innate lymphoid cells-From homeostasis to disease

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(3):e13147

Clearing the mist of autoimmunity pathogenesis: Dedication and persistence is key

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(2):e13141

What's in the tissue? Immunology's new playground

Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(1):e13127

Scandinavian journal of immunology: The first 50 years

Hoglund P
Letter: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(10):2531-2534

MHC class I molecules co-stimulate NK1.1 signaling and enhance Ca²⁺ flux in murine NK cells

Ganesan S; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1)

Role models that shaped Scandinavian immunology

Hoglund P
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:640578

Platelet-Mediated Protection of Cancer Cells From Immune Surveillance - Possible Implications for Cancer Immunotherapy

Schmied L; Hoglund P; Meinke S
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(7):E163-E166

Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia

Fragiadaki I; Papadakis S; Sevastaki G; Sfyridaki K; Mavroudi I; Goulielmos GN; Kanellou P; Mortberg A; Hoglund P; Gemenetzi K; Stamatopoulos K; Chatzidimitriou A; Palmblad J; Papadaki HA
Editorial comment: HEMASPHERE. 2020;4(3):e406

Congenital and Acquired Chronic Neutropenias: Challenges, Perspectives and Implementation of the EuNet-INNOCHRON Action

Papadaki HA; Mavroudi I; Almeida A; Bux J; Cichy J; Dale DC; Donadieu J; Hoglund P; Karanfilski O; Mecucci C; Palmblad J; Skokowa J; Stamatopoulos K; Touw I; Warren AJ; Welte K; Zeidler C; Dufour C
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;91(4):e12878

Natural killer cells and solid tumours: New therapies ahead?

Hoglund P
Review: TRANSFUSION MEDICINE REVIEWS. 2019;33(4):231-235

Complement as an Immune Barrier in Platelet Transfusion Refractoriness

Meinke S; Karlstrom C; Hoglund P
Editorial comment: TRANSFUSION. 2019;59(6):1945-1952

A longer duration of red blood cell storage is associated with a lower hemoglobin increase after blood transfusion: a cohort study

Ryden J; Clements M; Hellstrom-Lindberg E; Hoglund P; Edgren G
Review: PEDIATRIC BLOOD & CANCER. 2018;65(12):e27361

Ethnic benign neutropenia: A phenomenon finds an explanation

Palmblad J; Hoglund P
Letter: TRANSPLANTATION. 2017;101(5):e190-e192

Severe Transplantation-Mediated Alloimmune Thrombocytopenia in 2 Recipients of Organs From the Same Donor

Sonnerborg IV; Hoglund P; Nordstrom J; Wikman A; Wennberg L; Nowak G
Review: EXPERT REVIEW OF HEMATOLOGY. 2016;9(5):479-487

How we diagnose and treat neutropenia in adults

Palmblad J; Nilsson CC; Hoglund P; Papadaki HA
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2016;395:95-114

Dynamic Regulation of NK Cell Responsiveness

Kadri N; Wagner AK; Ganesan S; Karre K; Wickstrom S; Johansson MH; Hoglund P
Review: IMMUNOLOGICAL REVIEWS. 2015;267(1):167-177

Selection, tuning, and adaptation in mouse NK cell education

Kadri N; Thuy LT; Hoeglund P
Other: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2012;61(4):587-591

First International Meeting of the Thematic Centre for Immune Modulatory Therapies for Autoimmunity and Cancer (IMTAC) 13-14 June 2011, Ljusterö, Sweden.

Choudhury A; Höglund P; Kiessling R; Kärre K; Lundqvist A; Malmberg K; Mellstedt H; Scheynius A; Winqvist O; Osterborg A
Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734

Current perspectives of natural killer cell education by MHC class I molecules

Hoeglund P; Brodin P
Review: CURRENT OPINION IN IMMUNOLOGY. 2009;21(6):634-640

Natural killer cells in human autoimmunity

Flodstrom-Tullberg M; Bryceson YT; Shi F-D; Hoglund P; Ljunggren H-G
Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149

NK cell education: not an on-off switch but a tunable rheostat

Brodin P; Karre K; Hoglund P
Corrigendum: MOLECULAR IMMUNOLOGY. 2008;45(14):3863

TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation (vol 45, pg 3059, 2008)

Berglund JP; Mariotti-Ferrandiz E; Rosmaraki E; Hall H; Cazenave P-A; Six A; Hoglund P
Review: SEMINARS IN CANCER BIOLOGY. 2006;16(5):393-403

The dynamics of natural killer cell tolerance

Johansson MH; Hoglund P
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2006;16(5):331-332

Natural killer cells in cancer

Hoglund P; Klein E
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2006;2006(317):pe2

DNA damage and tumor surveillance: one trigger for two pathways.

Höglund P
Review: NANOPARTICLES FOR RATIONAL VACCINE DESIGN. 2006;298:259-277

NK cells in autoimmune disease

Johansson S; Hall H; Berg L; Höglund P
Review: TRENDS IN IMMUNOLOGY. 2005;26(11):613-618

NK cells:: elusive players in autoimmunity

Johansson S; Berg L; Hall H; Höglund P
Published conference paper: MOLECULAR IMMUNOLOGY. 2005;42(4):397-403

Computational modeling of human natural killer cell development suggests a selection process regulating coexpression of KIR with CD94/NKG2A

Salmon-Divon M; Höglund P; Johansson MH; Johansson S; Mehr R
Review: SEMINARS IN IMMUNOLOGY. 2003;15(6):317-324

The protean immune cell synapse:: a supramolecular structure with many functions

Davis DM; Igakura T; McCann FE; Carlin LM; Andersson K; Vanherberghen B; Sjöström A; Bangham CRM; Höglund P
Review: IMMUNOLOGICAL REVIEWS. 1999;169:139-146

Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems.

Ji H; Korganow AS; Mangialaio S; Höglund P; André I; Lühder F; Gonzalez A; Poirot L; Benoist C; Mathis D
Review: IMMUNOLOGICAL REVIEWS. 1997;155:11-28

Host MHC class I gene control of NK-cell specificity in the mouse

Hoglund P; Sundback J; OlssonAlheim MY; Johansson M; Salcedo M; Ohlen C; Ljunggren HG; Sentman CL; Karre K
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Forskningsbidrag

Dissecting natural killer cell education: from basic studies to improved immunotherapy of cancer

Swedish Research Council

1 January 2022 - 31 December 2024
Trombocytens roll för trombosbildning och koagulationrubbning vid Covid-19

Swedish Heart-Lung Foundation

1 January 2021 - 31 December 2021
Transfusion treatment of leukemia patients: predictors of transfusion outcome and immunological consequences of chronic transfusion dependence.

Swedish Cancer Society

1 January 2018
Scandinavian society for immunology meeting 2017

Swedish Research Council

1 June 2017 - 30 June 2017
Molecular and clinical studies of the development and function of NK cells.

Swedish Cancer Society

1 January 2017
Molecular and clinical studies of the development and function of NK cells.

Swedish Cancer Society

1 January 2016
Molecular and clinical studies of the development and function of NK cells.

Swedish Cancer Society

1 January 2015
Natural killer cell education and graft-versus-leukemia effects after stem cell transplantation.

Swedish Research Council

1 January 2013 - 31 December 2015
Molecular and cellular studies of NK cell education

Swedish Research Council

1 January 2012 - 31 December 2016

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