Petter Höglund

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Prefekt på institutionen för medicin, Huddinge och gruppledare för Immunological tolerance and transfusion immunology vid HERM, KI.

Utnämnd till professor i basal immunologi, särskilt kliniskt tillämpad cellterapi och transplantation, vid Karolinska Institutet 2011. Läs mer på min engelska profilsida

Artiklar

Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;100(2):e13374
Genetic polymorphisms in IL-2, IL-10 and FOXP3 are associated with autoimmune neutropaenia in early childhood and autoantibody specificity in a Danish cohort
Klove-Mogensen K; Steffensen R; Masmas TN; Glenthoj A; Jensen CF; Ratcliffe P; Hoglund P; Hasle H; Nielsen KR; Haunstrup TM
Article: HLA. 2024;103(3):e15429
High-resolution HLA genotyping identifies risk alleles in both class I and II for primary autoimmune neutropenia in early childhood in a Danish cohort
Klove-Mogensen K; Haunstrup TM; Masmas TN; Glenthoj A; Hoglund P; Hasle H; Nielsen KR; Steffensen R
Article: BLOOD ADVANCES. 2024;8(3):571-580
Clinical and immunological features in ACKR1/DARC-associated neutropenia
Palmblad J; Sohlberg E; Nilsson CC; Lindqvist H; Deneberg S; Ratcliffe P; Meinke S; Mortberg A; Klimkowska M; Hoglund P
Journal article: CLINICAL IMMUNOLOGY COMMUNICATIONS. 2023;3:31-36
HNA specificity and association to HLA-DRB1 and -DQB1 in patients with autoimmune neutropenia of early childhood
Kløve-Mogensen K; Steffensen R; Nielsen HL; Masmas TN; Glenthøj A; Jensen CF; Haunstrup TM; Ratcliffe P; Höglund P; Hasle H; Nielsen KR
Article: TRANSFUSION. 2023;63(11):2040-2051
Red blood cell alloimmunization in myelodysplastic syndromes: Associations with sex, DAT-positivity, and increased transfusion needs
Ryden J; Clements M; Wikman A; Hellstrom-Lindberg E; Edgren G; Hoglund P
Article: SCIENCE SIGNALING. 2023;16(780):eabq0752
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency
Schmied L; Luu TT; Sondergaard JN; Hald SH; Meinke S; Mohammad DK; Singh SB; Mayer C; Casoni GP; Chrobok M; Schlums H; Rota G; Truong HM; Westerberg LS; Guarda G; Alici E; Wagner AK; Kadri N; Bryceson YT; Saeed MB; Hoglund P
Article: HEMASPHERE. 2023;7(4):e872
The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Action
Fioredda F; Skokowa J; Tamary H; Spanoudakis M; Farruggia P; Almeida A; Guardo D; Hoglund P; Newburger PE; Palmblad J; Touw IP; Zeidler C; Warren AJ; Dale DC; Welte K; Dufour C; Papadaki HA
Article: INTERNATIONAL JOURNAL OF IMMUNOGENETICS. 2023;50(2):65-74
Genetic variations in low-to-medium-affinity Fcγ receptors and autoimmune neutropenia in early childhood in a Danish cohort
Klove-Mogensen K; Steffensen R; Masmas TN; Glenthoj A; Jensen CF; Haunstrup TM; Ratcliffe P; Hoglund P; Hasle H; Nielsen KR
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577
Adaptive single-KIR⁺NKG2C⁺ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
Haroun-Izquierdo A; Vincenti M; Netskar H; van Ooijen H; Zhang B; Bendzick L; Kanaya M; Momayyezi P; Li S; Wiiger MT; Hoel HJ; Krokeide SZ; Kremer V; Tjonnfjord G; Berggren S; Wikstroem K; Blomberg P; Alici E; Felices M; oenfelt B; Hoeglund P; Valamehr B; Ljunggren H-G; Bjoerklund A; Hammer Q; Kveberg L; Cichocki F; Miller JS; Malmberg K-J; Sohlberg E
Article: TRANSFUSION. 2022;62(8):1636-1642
ABO, secretor, and Lewis carbohydrate histo-blood groups are associated with autoimmune neutropenia of early childhood in Danish patients
Klove-Mogensen K; Steffensen R; Masmas TN; Glenthoj A; Haunstrup TM; Ratcliffe P; Hoglund P; Hasle H; Nielsen KR
Article: BLOOD. 2022;139(5):704-716
Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Netskar H; Lorenz S; Kanaya M; Kosugi-Kanaya M; Meinke S; Mortberg A; Hoglund P; Sundin M; Carlsson G; Palmblad J; Malmberg K-J
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312
FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development
Luu TT; Sondergaard JN; Pena-Perez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers BJ; Achour A; Kutter C; Hoglund P; Mansson R; Kadri N
Article: FRONTIERS IN PUBLIC HEALTH. 2022;10:1073318
Cryopreserved platelets in bleeding management in remote hospitals: A clinical feasibility study in Sweden
Wikman A; Diedrich B; Bjorling K; Forsberg P-O; Harstad A-M; Henningsson R; Hoglund P; Skold H; ostman L; Sandgren P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):224-233
Platelet transfusion improves clot formation and platelet function in severely thrombocytopenic haematology patients
Karlstrom C; Gryfelt G; Schmied L; Meinke S; Hoglund P
Article: MALARIA JOURNAL. 2021;20(1):441
Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes
Hedberg P; Sirel M; Moll K; Kiwuwa MS; Hoglund P; Ribacke U; Wahlgren M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1):e13037
The blood protein hCAP-18 in neutropenia: An 18-month experience of a new ELISA for clinical use
Mortberg A; Putsep K; Hoglund P
Article: LIFE SCIENCE ALLIANCE. 2021;4(4):e202000723
Short-term IL-15 priming leaves a long-lasting signalling imprint in mouse NK cells independently of a metabolic switch
Luu TT; Schmied L; Nguyen N-A; Wiel C; Meinke S; Mohammad DK; Bergo M; Alici E; Kadri N; Ganesan S; Hoglund P
Article: TRANSFUSION. 2021;61(4):1222-1234
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients
Mirlashari MR; Vetlesen A; Nissen-Meyer LSH; Naper C; Tjonnfjord GE; Njerve IU; Ezligini F; Landmark BF; Meinke S; Sandgren P; Hoglund P; Hetland G
Article: TRANSFUSION. 2021;61(2):464-473
Frequent platelet donation is associated with lymphopenia and risk of infections: A nationwide cohort study
Zhao J; Gabriel E; Norda R; Hoglund P; Baden L; Diedrich BA; Marits P; Enoksson SL; Gansner JM; Kaufman R; Dickman PW; Edgren G
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(6):e12997
Covid-19, SSI 50 years and Nobel: Three immunological reasons to remember 2020.
Höglund P; Ljunggren H-G; Jonsson R
Article: TRANSFUSION MEDICINE AND HEMOTHERAPY. 2020;47(5):385-395
Multicenter Study on Differential Human Neutrophil Antigen 2 Expression and Underlying Molecular Mechanisms
Flesch BK; Reil A; Nogues N; Canals C; Bugert P; Schulze TJ; Huiskes E; Porcelijn L; Hoglund P; Ratcliffe P; Schoenbacher M; Kerchrom H; Kellershohn J; Bayat B
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504
IL-15 and CD155 expression regulate LAT expression in murine DNAM1⁺ NK cells, enhancing their effectors functions
Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Hoglund P; Kadri N
Article: TRANSFUSION. 2019;59(3):945-952
HLA-selected platelets for platelet refractory patients with HLA antibodies: a single-center experience
Karlstrom C; Linjama T; Edgren G; Lauronen J; Wikman A; Hoglund P
Article: LEUKEMIA. 2019;33(2):522-527
Male sex and the pattern of recurrent myeloid mutations are strong independent predictors of blood transfusion intensity in patients with myelodysplastic syndromes
Ryden J; Edgren G; Karimi M; Walldin G; Tobiasson M; Wikman A; Hellstrom-Lindberg E; Hoglund P
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249
The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Le Blanc K; Kadri N; Hoglund P
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;88(6):e12731
Seminal immunologic discoveries with direct clinical implications: The 2018 Nobel Prize in Physiology or Medicine honours discoveries in cancer immunotherapy.
Ljunggren H-G; Jonsson R; Höglund P
Article: VOX SANGUINIS. 2018;113(8):779-786
Anti-D quantification in relation to anti-D titre, middle cerebral artery Doppler measurement and clinical outcome in RhD-immunized pregnancies
Wikman A; Jalkesten E; Ajne G; Hoeglund P; Mortberg A; Tiblad E
Article: TRANSFUSION. 2018;58(11):2657-2668
Cryopreservation of buffy coat-derived platelet concentrates photochemically treated with amotosalen and UVA light
Meinke S; Wikman A; Gryfelt G; Hultenby K; Uhlin M; Hoeglund P; Sandgren P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224
Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes
Palma M; Krstic A; Perez LP; Bergloef A; Meinke S; Wang Q; Blomberg KEM; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; De Paepe A; Hoeglund P; Kimby E; OEsterborg A; Mansson R; Smith CIE
Article: THROMBOSIS RESEARCH. 2018;162:69-76
Adding to the complexity of fetal and neonatal alloimmune thrombocytopenia: Reduced fibrinogen binding in the presence of anti-HPA-1a antibody and hypo-responsive neonatal platelets
Refsum E; Meinke S; Gryfelt G; Wikman A; Hoglund P
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:3173
Inhibitory Receptor Crosslinking Quantitatively Dampens Calcium Flux Induced by Activating Receptor Triggering in NK Cells
Ganesan S; Hoglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142
The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education
Ganesan S; Luu TT; Chambers BJ; Meinke S; Brodin P; Vivier E; Wetzel DM; Koleske AJ; Kadri N; Hoglund P
Article: NATURE COMMUNICATIONS. 2017;8(1):224
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia
Yougbare I; Tai W-S; Zdravic D; Oswald BE; Lang S; Zhu G; Leong-Poi H; Qu D; Yu L; Dunk C; Zhang J; Sled JG; Lye SJ; Brkic J; Peng C; Hoglund P; Croy BA; Adamson SL; Wen X-Y; Stewart DJ; Freedman J; Ni H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;85(6):417-424
TLR-Stimulated Eosinophils Mediate Recruitment and Activation of NK Cells In Vivo
O'Flaherty SM; Sutummaporn K; Haggtoft WL; Worrall AP; Rizzo M; Braniste V; Hoglund P; Kadri N; Chambers BJ
Article: NATURE COMMUNICATIONS. 2017;8:15627
Expression of CD226 is associated to but not required for NK cell education
Wagner AK; Kadri N; Snall J; Brodin P; Gilfillan S; Colonna M; Bernhardt GN; Hoglund P; Karre K; Chambers BJ
Journal article: ISBT SCIENCE SERIES. 2017;12(1):148-153
HLA‐stripped platelets: preclinical developments and clinical outlooks
Meinke S; Karlström C; Gryfelt G; Wikman A; Höglund P
Article: TRANSFUSION MEDICINE. 2017;27(1):43-51
Characterisation of maternal human leukocyte antigen class I antibodies in suspected foetal and neonatal alloimmune thrombocytopenia
Refsum E; Mortberg A; Dahl J; Meinke S; Auvinen M-K; Westgren M; Reilly M; Hoglund P; Wikman A
Article: VOX SANGUINIS. 2017;112(1):33-39
Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study
Gulliksson H; Meinke S; Ravizza A; Larsson L; Hoglund P
Article: SCIENTIFIC REPORTS. 2016;6:37996
Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+dendritic cells
Thuy TL; Ganesan S; Wagner AK; Sarhan D; Meinke S; Garbi N; Haemmerling G; Alici E; Karre K; Chambers BJ; Hoglund P; Kadri N
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769
In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation
Lakshmikanth T; Heuts F; Muvva SSVJR; Wallin RPA; Persson A-K; Fauriat C; Applequist SE; Ljunggren H-G; Hoglund P; Karre K; Svensson M; Juarez JG
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2016;434:9-15
Sensitive detection of platelet-specific antibodies with a modified MAIPA using biotinylated antibodies and streptavidin-coated beads
Mortberg A; Meinke S; Berg P; Killie MK; Kjeldsen-Kragh J; Jaras K; Refsum E; Hoglund P; Wikman A
Article: IMMUNOLOGY AND CELL BIOLOGY. 2016;94(2):177-184
Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice
Brauner H; Hall HT; Flodstrom-Tullberg M; Karre K; Hoglund P; Johansson S
Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123
Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response
Wagner AK; Wickstrom SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Hoglund P; Carbone E; Johansson MH; Karre K
Article: TRANSFUSION. 2016;56(2):370-369
Platelets made HLA deficient by acid treatment aggregate normally and escape destruction by complement and phagocytes in the presence of HLA antibodies
Meinke S; Sandgren P; Mortberg A; Karlstrom C; Kadri N; Wikman A; Hoglund P
Article: TRANSFUSION. 2014;54(3):602-612
Random aggregates in newly produced platelet units are associated with platelet activation and release of the immunomodulatory factors sCD40L and RANTES
Sandgren P; Meinke S; Eckert E; Douagi I; Wikman A; Hoglund P
Article: BLOOD TRANSFUSION. 2013;11(3):456-459
A severe haemolytic transfusion reaction caused by anti-Le^a active at 37°C
Hoglund P; Rosengren-Lindquist R; Wikman AT
Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65
Natural killer cell inhibitory receptor expression in humans and mice: a closer look
Sternberg-Simon M; Brodin P; Pickman Y; Onfelt B; Karre K; Malmberg K-J; Hoglund P; Mehr R
Article: ACTA DERMATO-VENEREOLOGICA. 2012;92(6):609-614
No Association between Infections, HLA Type and Other Transplant-related Factors and Risk of Cutaneous Squamous Cell Carcinoma in Solid Organ Transplant Recipients
Ingvar A; Smedby KE; Lindelof B; Fernberg P; Bellocco R; Tufveson G; Hoglund P; Adami J
Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226
Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets
Brodin P; Lakshmikanth T; Karre K; Hoglund P
Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2011;11(11):2472-2482
Time Trends in Risk and Risk Determinants of Non-Hodgkin Lymphoma in Solid Organ Transplant Recipients
Fernberg P; Edgren G; Adami J; Ingvar A; Bellocco R; Tufveson G; Hoglund P; Kinch A; Simard JF; Baecklund E; Lindelof B; Pawitan Y; Smedby KE
Article: BIOPHYSICAL JOURNAL. 2011;101(5):1257-1269
A Modified FCCS Procedure Applied to Ly49A-MHC Class I cis-Interaction Studies in Cell Membranes
Stromqvist J; Johansson S; Xu L; Ohsugi Y; Andersson K; Muto H; Kinjo M; Hoglund P; Widengren J
Article: JOURNAL OF IMMUNOLOGY. 2011;187(2):760-773
Simulations of the NK Cell Immune Synapse Reveal that Activation Thresholds Can Be Established by Inhibitory Receptors Acting Locally
Kaplan A; Kotzer S; Almeida CR; Kohen R; Halpert G; Salmon-Divon M; Koehler K; Hoeglund P; Davis DM; Mehr R
Article: PLOS ONE. 2010;5(10):e13174
Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice
Brodin P; Lakshmikanth T; Mehr R; Johansson MH; Duru AD; Achour A; Salmon-Divon M; Karre K; Hoglund P; Johansson S
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2010;25(8):2764-2771
Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma
Ingvar A; Smedby KE; Lindelof B; Fernberg P; Bellocco R; Tufveson G; Hoglund P; Adami J
Article: JOURNAL OF IMMUNOLOGY. 2010;184(5):2272-2280
Distinct Phenotype and Function of NK Cells in the Pancreas of Nonobese Diabetic Mice
Brauner H; Elemans M; Lemos S; Broberger C; Holmberg D; Flodstrom-Tullberg M; Karre K; Hoglund P
Article: JOURNAL OF AUTOIMMUNITY. 2010;34(1):66-72
AIRE deficiency leads to impaired iNKT cell development
Lindh E; Rosmaraki E; Berg L; Brauner H; Karlsson MCI; Peltonen L; Hoglund P; Winqvist O
Article: PLOS ONE. 2009;4(6):e6046
Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice
Johansson S; Salmon-Divon M; Johansson MH; Pickman Y; Brodin P; Karre K; Mehr R; Hoglund P
Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(5):1251-1263
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
Lakshmikanth T; Burke S; Ali TH; Kimpfler S; Ursini F; Ruggeri L; Capanni M; Umansky V; Paschen A; Sucker A; Pende D; Groh V; Biassoni R; Hoglund P; Kato M; Shibuya K; Schadendorf D; Anichini A; Ferrone S; Velardi A; Karre K; Shibuya A; Carbone E; Colucci F
Article: IMMUNITY. 2009;30(3):337-347
A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHIC Class I for Natural Killer Cell Education
Chalifour A; Scarpellino L; Back J; Brodin P; Devevre E; Gros F; Levy F; Leclercq G; Hoglund P; Beermann F; Held W
Article: BLOOD. 2009;113(11):2434-2441
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
Brodin P; Lakshmikanth T; Johansson S; Karre K; Hoglund P
Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468
Distinct and Overlapping Patterns of Cytokine Regulation of Thymic and Bone Marrow-Derived NK Cell Development
Cheng M; Charoudeh HN; Brodin P; Tang Y; Lakshmikanth T; Hoglund P; Jacobsen SEW; Sitnicka E
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937
Beyond licensing and disarming: A quantitative view on NK-cell education
Brodin P; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):3191-3199
Increased diabetes development and decreased function of CD4⁺ CD25⁺ Treg in the absence of a functional DAP12 adaptor protein
Hall HTL; Sjolin H; Brauner H; Tomasello E; Dalod M; Vivier E; Hoglund P
Article: MOLECULAR IMMUNOLOGY. 2008;45(11):3059-3064
TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation
Berglund JP; Mariotti-Ferrandiz E; Rosmaraki E; Hall H; Cazenave P-A; Six A; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2007;37(2):516-527
Quantifying the reduction in accessibility of the inhibitory NK cell receptor Ly49A caused by binding MHC class I proteins in cis
Andersson KE; Williams GS; Davis DM; Hoglund P
Article: JOURNAL OF IMMUNOLOGY. 2006;177(5):2908-2916
DAP12 signalling regulates plasmacytoid ddendritic cell homeostasis and down-modulates their function during viral infection
Sjolin H; Robbins SH; Bessou G; Hidmark A; Tomasello E; Johansson M; Hall H; Charifi F; Hedestam GBK; Biron CA; Karre K; Hoglund P; Vivier E; Dalod M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2006;36(2):264-266
Induced peripheral regulatory T cells:: The family grows larger
Höglund P
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2005;307(1-2):73-81
Impact of plastic adhesion in vitro on analysis of Th1 and Th2 cytokines and immune cell distribution from mice with multiple low-dose streptozotocin-induced diabetes
Thorvaldson L; Johansson SE; Höglund P; Sandler S
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2005;201(7):1145-1155
Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules
Johansson S; Johansson M; Rosmaraki E; Vahlne G; Mehr R; Salmon-Divon M; Lemonnier F; Kärre K; Höglund P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(48):16873-16878
Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells
Vanherberghen B; Andersson K; Carlin LM; Hoen ENMN; Williams GS; Höglund P; Davis DM
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(11):3091-3101
Reduced antigen concentration and costimulatory blockade increase IFN-γ secretion in naive CD8⁺ T cells
Hall HTL; Petrovic J; Höglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):134-142
Inhibition of the proteasome reduces transfer-induced diabetes in nonobese diabetic mice
Petrovic J; Hall H; Mehr R; Glas R; Höglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2004;34(6):1646-1653
Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo -: role of KARAP/DAP12-dependent and -independent pathways
Öberg L; Johansson S; Michaëlsson J; Tomasello E; Vivier E; Kärre K; Höglund P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(1):71-78
Low number of H-2D^d-negative haematopoietic cells in mixed bone marrow chimeras convey in vivo tolerance to H-2D^d-negative cells but fail to prevent resistance to H-2D^d-negative leukaemia
Johansson MH; Höglund P
Article: INTERNATIONAL IMMUNOLOGY. 2004;16(1):1-11
Broadly impaired NK cell function in nonobese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro
Johansson SE; Hall H; Björklund J; Höglund P
Article: IMMUNOLOGY. 2003;110(3):313-321
MHC-dependent and -independent modulation of endogenous Ly49 receptors on NK1.1⁺ T lymphocytes directed by T-cell receptor type
Sköld M; Stenström M; Sidobre S; Höglund P; Kronenberg M; Cardell S
Article: CANCER IMMUNITY. 2003;3:6
The uterine cervix--a new member of the family of immunologically exceptional sites?
Höglund P; Kärre K; Klein G
Journal article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2003;10(2-4):183-192
Models for natural killer cell repertoire formation.
Salmon-Divon M; Höglund P; Mehr R
Article: BULLETIN OF MATHEMATICAL BIOLOGY. 2003;65(2):199-218
Generation of the natural killer cell repertoire:: The sequential vs. the two-step selection model
Salmon-Divon M; Höglund P; Mehr R
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2001;194(10):1519-1530
Acquisition of external major histocompatibility complex class I molecules by natural killer cells expressing inhibitory Ly49 receptors
Sjöström A; Eriksson M; Cerboni C; Johansson MH; Sentman CL; Kärre K; Höglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(2):525-533
Differential effects on T cell and NK cell development by tissue-specific expression of H-2D^d transgene
Johansson MH; Bieberich C; Kåse-Sjöström A; Yoshioka T; Höglund E; Christy BA; Scangos G; Kärre K; Jay G; Höglund P
Article: INTERNATIONAL IMMUNOLOGY. 1999;11(8):1239-1246
Natural killing of MHC class I^- lymphoblasts by NK cells from long-term bone marrow culture requires effector cell expression of Ly49 receptors
Lindberg J; Martín-Fontecha A; Höglund P
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1999;189(2):331-339
Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes.
Höglund P; Mintern J; Waltzinger C; Heath W; Benoist C; Mathis D
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(12):4198-4206
α1/α2 domains of H-2D^d, but not H-2L^d, induce "missing self" reactivity in vivo -: No effect of H-2L^d on protection against NK cells expressing the inhibitory receptor Ly49G2
Johansson MH; Höglund E; Nakamura MC; Ryan JC; Höglund P
Article: JOURNAL OF IMMUNOLOGY. 1998;161(11):6133-6138
External and internal calibration of the MHC class I-specific receptor Ly49A on murine natural killer cells
Kåse A; Johansson MH; Olsson-Alheim MY; Kårre A; Höglund P
Article: DIABETES. 1998;47(8):1207-1211
Interleukin-4 deficiency does not exacerbate disease in NOD mice.
Wang B; Gonzalez A; Höglund P; Katz JD; Benoist C; Mathis D
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1998;187(3):427-432
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes.
Lühder F; Höglund P; Allison JP; Benoist C; Mathis D
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(1):370-378
β2-Microglobulin-deficient NK cells show increased sensitivity to MHC class I-mediated inhibition, but self tolerance does not depend upon target cell expression of H-2K^b and D^b heavy chains
Höglund P; Glas R; Ménard C; Kåse A; Johansson MH; Franksson L; Lemmonier F; Kärre K
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 1997;186(3):353-364
Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene
Johansson MH; Bieberich C; Jay G; Karre K; Hoglund P
Article: TRANSPLANTATION. 1997;63(1):119-123
Major histocompatibility complex class I-independent killing of xenogenic targets by rat allospecific natural killer cells
Torgersen KM; Salcedo M; Vaage JT; Naper C; Rolstad B; Ljunggren HG; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(1):342-345
Lack of F-1 anti-parental resistance in H-2(b/d) F-1 hybrids devoid of beta(2)-microglobulin
Hoglund P; OlssonAlheim MY; Johansson M; Karre K; Sentman CL
Article: CARCINOGENESIS. 1995;16(10):2515-2521
CHARACTERIZATION OF HUMAN BUCCAL EPITHELIAL-CELLS TRANSFECTED WITH THE SIMIAN-VIRUS-40 T-ANTIGEN GENE
KULKARNI PS; SUNDQVIST K; BETSHOLTZ C; HOGLUND P; WIMAN KG; ZHIVOTOVSKY B; BERTOLERO F; LIU Y; GRAFSTROM RC
Article: TRANSPLANTATION. 1995;60(3):281-286
NATURAL-KILLER-CELL INTERACTION WITH MURINE ALLOGENEIC MHC CLASS-I MOLECULES
SALCEDO M; HOGLUND P; LJUNGGREN HG
Article: MOLECULAR IMMUNOLOGY. 1995;32(11):789-794
ALTERED MHC CLASS-I PRESENTED PEPTIDE REPERTOIRE IS NOT SUFFICIENT TO INDUCE NK CELL-MEDIATED F-1-HYBRID RESISTANCE
SALCEDO M; HOGLUND P; ACHOUR A; THORPE CJ; LJUNGGREN HG
Article: CANCER RESEARCH. 1995;55(9):1911-1916
REJECTION OF TUMORS IN MICE WITH SEVERE COMBINED IMMUNODEFICIENCY SYNDROME DETERMINED BY THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I EXPRESSION ON THE GRAFT
GLAS R; WALDENSTROM M; HOGLUND P; KLEIN G; KARRE K; LJUNGGREN HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(5):1286-1291
INHIBITION OF NATURAL-KILLER CELL-MEDIATED BONE-MARROW GRAFT-REJECTION BY ALLOGENEIC MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I, BUT NOT CLASS-II MOLECULES
OHLEN C; HOGLUND P; SENTMAN CL; CARBONE E; LJUNGGREN HG; KOLLER B; KARRE K
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Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13347
Chlamydia pathogenesis in mice: Male immunity and the outcome of female infection
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(6):e13340
The prize of prizes: mRNA research paving the way for COVID-19 vaccine success wins the Nobel Prize in Physiology or Medicine 2023
Buggert M; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;97(6)
SSI 2023 in Turku: The 49th annual meeting of the Scandinavian Society for Immunology coming up
Hoglund P
Review: HEMASPHERE. 2023;7(1):e814
Autoimmune Neutropenias: Update on Clinical and Biological Features in Children and Adults
Fioredda F; Dufour C; Hoglund P; Papadaki HA; Palmblad J
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(6)
Nobel 2022: An extraordinary achievement relevant to immunity
Hoglund P; Ljunggren H-G; Jonsson R
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(5)
Antigen presentation in mucosal tissues: Dendritic cells and GP2
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(3)
Gender bias in complex autoimmune disorders: Clinically characterized cohorts pave the way for new knowledge
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(2)
SJI 50 years: Immunosurveillance in the brain and our highest impact factor ever
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13199
Resource article: A new category of SJI publications
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(6)
Two immunology happenings this June: Iceland hosts SSI 2022 and follicular T cells celebrate SJI 50 years
Hoglund P
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2022;97(6):E207-E210
Mutation in the TACI gene and autoimmune neutropenia: A case report
Bergman P; Broliden P-A; Ratcliffe P; Lourda M; Flesch B; Hoglund P; Palmblad J
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(5):e13173
Immunology according to Dembic: Preserving integrity is key
Corthay A; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(4):e13165
Innate lymphoid cells-From homeostasis to disease
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(3):e13147
Clearing the mist of autoimmunity pathogenesis: Dedication and persistence is key
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(2):e13141
What's in the tissue? Immunology's new playground
Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;95(1):e13127
Scandinavian journal of immunology: The first 50 years
Hoglund P
Letter: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(10):2531-2534
MHC class I molecules co-stimulate NK1.1 signaling and enhance Ca²⁺ flux in murine NK cells
Ganesan S; Hoglund P
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(1)
Role models that shaped Scandinavian immunology
Hoglund P
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:640578
Platelet-Mediated Protection of Cancer Cells From Immune Surveillance - Possible Implications for Cancer Immunotherapy
Schmied L; Hoglund P; Meinke S
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(7):E163-E166
Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia
Fragiadaki I; Papadakis S; Sevastaki G; Sfyridaki K; Mavroudi I; Goulielmos GN; Kanellou P; Mortberg A; Hoglund P; Gemenetzi K; Stamatopoulos K; Chatzidimitriou A; Palmblad J; Papadaki HA
Editorial comment: HEMASPHERE. 2020;4(3):e406
Congenital and Acquired Chronic Neutropenias: Challenges, Perspectives and Implementation of the EuNet-INNOCHRON Action
Papadaki HA; Mavroudi I; Almeida A; Bux J; Cichy J; Dale DC; Donadieu J; Hoglund P; Karanfilski O; Mecucci C; Palmblad J; Skokowa J; Stamatopoulos K; Touw I; Warren AJ; Welte K; Zeidler C; Dufour C
Editorial comment: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;91(4):e12878
Natural killer cells and solid tumours: New therapies ahead?
Hoglund P
Review: TRANSFUSION MEDICINE REVIEWS. 2019;33(4):231-235
Complement as an Immune Barrier in Platelet Transfusion Refractoriness
Meinke S; Karlstrom C; Hoglund P
Editorial comment: TRANSFUSION. 2019;59(6):1945-1952
A longer duration of red blood cell storage is associated with a lower hemoglobin increase after blood transfusion: a cohort study
Ryden J; Clements M; Hellstrom-Lindberg E; Hoglund P; Edgren G
Review: PEDIATRIC BLOOD AND CANCER. 2018;65(12):e27361
Ethnic benign neutropenia: A phenomenon finds an explanation
Palmblad J; Hoglund P
Letter: TRANSPLANTATION. 2017;101(5):e190-e192
Severe Transplantation-Mediated Alloimmune Thrombocytopenia in 2 Recipients of Organs From the Same Donor
Sonnerborg IV; Hoglund P; Nordstrom J; Wikman A; Wennberg L; Nowak G
Review: EXPERT REVIEW OF HEMATOLOGY. 2016;9(5):479-487
How we diagnose and treat neutropenia in adults
Palmblad J; Nilsson CC; Hoglund P; Papadaki HA
Review: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY. 2016;395:95-114
Dynamic Regulation of NK Cell Responsiveness
Kadri N; Wagner AK; Ganesan S; Karre K; Wickstrom S; Johansson MH; Hoglund P
Review: IMMUNOLOGICAL REVIEWS. 2015;267(1):167-177
Selection, tuning, and adaptation in mouse NK cell education
Kadri N; Thuy LT; Hoeglund P
Other: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2012;61(4):587-591
First International Meeting of the Thematic Centre for Immune Modulatory Therapies for Autoimmunity and Cancer (IMTAC) 13-14 June 2011, Ljusterö, Sweden.
Choudhury A; Höglund P; Kiessling R; Kärre K; Lundqvist A; Malmberg K; Mellstedt H; Scheynius A; Winqvist O; Osterborg A
Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734
Current perspectives of natural killer cell education by MHC class I molecules
Hoeglund P; Brodin P
Review: CURRENT OPINION IN IMMUNOLOGY. 2009;21(6):634-640
Natural killer cells in human autoimmunity
Flodstrom-Tullberg M; Bryceson YT; Shi F-D; Hoglund P; Ljunggren H-G
Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149
NK cell education: not an on-off switch but a tunable rheostat
Brodin P; Karre K; Hoglund P
Corrigendum: MOLECULAR IMMUNOLOGY. 2008;45(14):3863
TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation (vol 45, pg 3059, 2008)
Berglund JP; Mariotti-Ferrandiz E; Rosmaraki E; Hall H; Cazenave P-A; Six A; Hoglund P
Review: SEMINARS IN CANCER BIOLOGY. 2006;16(5):393-403
The dynamics of natural killer cell tolerance
Johansson MH; Hoglund P
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2006;16(5):331-332
Natural killer cells in cancer
Hoglund P; Klein E
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2006;2006(317):pe2
DNA damage and tumor surveillance: one trigger for two pathways.
Höglund P
Review: CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY. 2006;298:259-277
NK cells in autoimmune disease
Johansson S; Hall H; Berg L; Höglund P
Review: TRENDS IN IMMUNOLOGY. 2005;26(11):613-618
NK cells:: elusive players in autoimmunity
Johansson S; Berg L; Hall H; Höglund P
Published conference paper: MOLECULAR IMMUNOLOGY. 2005;42(4):397-403
Computational modeling of human natural killer cell development suggests a selection process regulating coexpression of KIR with CD94/NKG2A
Salmon-Divon M; Höglund P; Johansson MH; Johansson S; Mehr R
Review: SEMINARS IN IMMUNOLOGY. 2003;15(6):317-324
The protean immune cell synapse:: a supramolecular structure with many functions
Davis DM; Igakura T; McCann FE; Carlin LM; Andersson K; Vanherberghen B; Sjöström A; Bangham CRM; Höglund P
Review: IMMUNOLOGICAL REVIEWS. 1999;169:139-146
Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems.
Ji H; Korganow AS; Mangialaio S; Höglund P; André I; Lühder F; Gonzalez A; Poirot L; Benoist C; Mathis D
Review: IMMUNOLOGICAL REVIEWS. 1997;155:11-28
Host MHC class I gene control of NK-cell specificity in the mouse
Hoglund P; Sundback J; OlssonAlheim MY; Johansson M; Salcedo M; Ohlen C; Ljunggren HG; Sentman CL; Karre K
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Forskningsbidrag

Dissecting natural killer cell education: from basic studies to improved immunotherapy of cancer
Swedish Research Council
1 January 2022 - 31 December 2024
Trombocytens roll för trombosbildning och koagulationrubbning vid Covid-19
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2021
Transfusion treatment of leukemia patients: predictors of transfusion outcome and immunological consequences of chronic transfusion dependence.
Swedish Cancer Society
1 January 2018
Scandinavian society for immunology meeting 2017
Swedish Research Council
1 June 2017 - 30 June 2017
Molecular and clinical studies of the development and function of NK cells.
Swedish Cancer Society
1 January 2017
Molecular and clinical studies of the development and function of NK cells.
Swedish Cancer Society
1 January 2016
Molecular and clinical studies of the development and function of NK cells.
Swedish Cancer Society
1 January 2015
Natural killer cell education and graft-versus-leukemia effects after stem cell transplantation.
Swedish Research Council
1 January 2013 - 31 December 2015
Molecular and cellular studies of NK cell education
Swedish Research Council
1 January 2012 - 31 December 2016

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