Paul Lichtenstein

Paul Lichtenstein

Professor | Viceprefekt | Docent
Telefon: +46852487424
Besöksadress: Nobels väg 12a, 17165 Solna
Postadress: C8 Medicinsk epidemiologi och biostatistik, C8 MEB Lichtenstein, 171 77 Stockholm

Om mig

  • Jag är professor i genetisk epidemiologi och studierektor för institutionens forskarutbildning. Jag är också viceprefekt och medlem i ledningsgruppen vid institutionen.

    Forskningen inom min grupp på Institutionen för medicinsk epidemiologi och biostatistik är huvudsakligen koncentrad på studier av tvillingar och familjer för att förstå hur arv och miljö påverkar både hälsa och beteende. Studierna baseras på det Svenska Tvillingregistret (som består av mer än 200 000 tvillingar) och andra svenska register såsom Flergenerations-registret. Gruppen genomför kvantitativ genetiska studier - dvs försöka värdera den relativa betydelsen av arv och miljö för olika egenskaper - och co-twin-control-studier, där betydelsen av exponeringar värderas efter kontroll av genetisk predisposition för sjukdomen. Forskningen är tvärvetenskaplig och inkluderar bland annat medicinska, genetiska, epidemiologiska, sociologiska och psykologiska frågeställningar.

Forskningsbeskrivning

  • FORSKNINGSPROJEKT
    - Twin Study of Child and Adolescent Development - TCHAD
    - Barn- och Ungdomsstudien i Sverige (CATSS)
    - Causes and consequences of psychiatric disorders – Orsaker till och konsekvenser av psykiatriska sjukdomar

    FORSKARE OCH FORSKARASSISTENTER I GRUPPEN
    Agnieszka Butwicka
    Erik Pettersson
    Zheng Chang
    Márta Radó
    Mark Taylor

    POST DOCS
    Lotfi Khemiri

Utvalda publikationer

  • Article: JAMA PSYCHIATRY. 2016;73(12):1268-1275
    Latvala A; Kuja-Halkola R; Ruck C; D'Onofrio BM; Jernberg T; Almqvist C; Mataix-Cols D; Larsson H; Lichtenstein P
  • Article: MOLECULAR PSYCHIATRY. 2016;21(5):717-721
    Pettersson E; Larsson H; Lichtenstein P
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(4):1098-1103
    Reichenberg A; Cederlof M; McMillan A; Trzaskowski M; Kapara O; Fruchter E; Ginat K; Davidson M; Weiser M; Larsson H; Plomin R; Lichtenstein P
  • Article: JAMA PSYCHIATRY. 2014;71(4):432-438
    D'Onofrio BM; Rickert ME; Frans E; Kuja-Halkola R; Almqvist C; Sjolander A; Larsson H; Lichtenstein P
  • Article: JAMA PSYCHIATRY. 2014;71(3):319-325
    Chang Z; Lichtenstein P; D'Onofrio BM; Sjolander A; Larsson H
  • Article: JAMA PSYCHIATRY. 2014;71(3):326-333
    Fazel S; Wolf A; Pillas D; Lichtenstein P; Langstrom N
  • Article: THE LANCET. 2013;382(9905):1646-1654
    Fazel S; Wolf A; Langstrom N; Newton CR; Lichtenstein P
  • Article: JAMA PSYCHIATRY. 2013;70(11):1231-1240
    D'Onofrio BM; Class QA; Rickert ME; Larsson H; Langstrom N; Lichtenstein P
  • Article: NATURE GENETICS. 2013;45(9):984-994
    Lee SH; Ripke S; Neale BM; Faraone SV; Purcell SM; Perlis RH; Mowry BJ; Thapar A; Goddard ME; Witte JS; Absher D; Agartz I; Akil H; Amin F; Andreassen OA; Anjorin A; Anney R; Anttila V; Arking DE; Asherson P; Azevedo MH; Backlund L; Badner JA; Bailey AJ; Banaschewski T; Barchas JD; Barnes MR; Barrett TB; Bass N; Battaglia A; Bauer M; Bayes M; Bellivier F; Bergen SE; Berrettini W; Betancur C; Bettecken T; Biederman J; Binder EB; Black DW; Blackwood DHR; Bloss CS; Boehnke M; Boomsma DI; Breen G; Breuer R; Bruggeman R; Cormican P; Buccola NG; Buitelaar JK; Bunney WE; Buxbaum JD; Byerley WF; Byrne EM; Caesar S; Cahn W; Cantor RM; Casas M; Chakravarti A; Chambert K; Choudhury K; Cichon S; Cloninger CR; Collier DA; Cook EH; Coon H; Cormand B; Corvin A; Coryell WH; Craig DW; Craig IW; Crosbie J; Cuccaro ML; Curtis D; Czamara D; Datta S; Dawson G; Day R; De Geus EJ; Degenhardt F; Djurovic S; Donohoe GJ; Doyle AE; Duan J; Dudbridge F; Duketis E; Ebstein RP; Edenberg HJ; Elia J; Ennis S; Etain B; Fanous A; Farmer AE; Ferrier IN; Flickinger M; Fombonne E; Foroud T; Frank J; Franke B; Fraser C; Freedman R; Freimer NB; Freitag CM; Friedl M; Frisen L; Gallagher L; Gejman PV; Georgieva L; Gershon ES; Geschwind DH; Giegling I; Gill M; Gordon SD; Gordon-Smith K; Green EK; Greenwood TA; Grice DE; Gross M; Grozeva D; Guan W; Gurling H; De Haan L; Haines JL; Hakonarson H; Hallmayer J; Hamilton SP; Hamshere ML; Hansen TF; Hartmann AM; Hautzinger M; Heath AC; Henders AK; Herms S; Hickie IB; Hipolito M; Hoefels S; Holmans PA; Holsboer F; Hoogendijk WJ; Hottenga J-J; Hultman CM; Hus V; Ingason A; Ising M; Jamain S; Jones EG; Jones I; Jones L; Tzeng J-Y; Kaehler AK; Kahn RS; Kandaswamy R; Keller MC; Kennedy JL; Kenny E; Kent L; Kim Y; Kirov GK; Klauck SM; Klei L; Knowles JA; Kohli MA; Koller DL; Konte B; Korszun A; Krabbendam L; Krasucki R; Kuntsi J; Kwan P; Landen M; Langstrom N; Lathrop M; Lawrence J; Lawson WB; Leboyer M; Ledbetter DH; Lee PH; Lencz T; Lesch K-P; Levinson DF; Lewis CM; Li J; Lichtenstein P; Lieberman JA; Lin D-Y; Linszen DH; Liu C; Lohoff FW; Loo SK; Lord C; Lowe JK; Lucae S; MacIntyre DJ; Madden PAF; Maestrini E; Magnusson PKE; Mahon PB; Maier W; Malhotra AK; Mane SM; Martin CL; Martin NG; Mattheisen M; Matthews K; Mattingsdal M; McCarroll SA; McGhee KA; McGough JJ; McGrath PJ; McGuffin P; McInnis MG; McIntosh A; McKinney R; McLean AW; McMahon FJ; McMahon WM; McQuillin A; Medeiros H; Medland SE; Meier S; Melle I; Meng F; Meyer J; Middeldorp CM; Middleton L; Milanova V; Miranda A; Monaco AP; Montgomery GW; Moran JL; Moreno-De-Luca D; Morken G; Morris DW; Morrow EM; Moskvina V; Muglia P; Muehleisen TW; Muir WJ; Mueller-Myhsok B; Murtha M; Myers RM; Myin-Germeys I; Neale MC; Nelson SF; Nievergelt CM; Nikolov I; Nimgaonkar V; Nolen WA; Noethen MM; Nurnberger JI; Nwulia EA; Nyholt DR; O'Dushlaine C; Oades RD; Olincy A; Oliveira G; Olsen L; Ophoff RA; Osby U; Owen MJ; Palotie A; Parr JR; Paterson AD; Pato CN; Pato MT; Penninx BW; Pergadia ML; Pericak-Vance MA; Pickard BS; Pimm J; Piven J; Posthuma D; Potash JB; Poustka F; Propping P; Puri V; Quested DJ; Quinn EM; Antoni Ramos-Quiroga J; Rasmussen HB; Raychaudhuri S; Rehnstroem K; Reif A; Ribases M; Rice JP; Rietschel M; Roeder K; Roeyers H; Rossin L; Rothenberger A; Rouleau G; Ruderfer D; Rujescu D; Sanders AR; Sanders SJ; Santangelo SL; Sergeant JA; Schachar R; Schalling M; Schatzberg AF; Scheftner WA; Schellenberg GD; Scherer SW; Schork NJ; Schulze TG; Schumacher J; Schwarz M; Scolnick E; Scott LJ; Shi J; Shilling PD; Shyn SI; Silverman JM; Slager SL; Smalley SL; Smit JH; Smith EN; Sonuga-Barke EJS; St Clair D; State M; Steffens M; Steinhausen H-C; Strauss JS; Strohmaier J; Stroup TS; Sutcliffe JS; Szatmari P; Szelinger S; Thirumalai S; Thompson RC; Todorov AA; Tozzi F; Treutlein J; Uhr M; van den Oord EJCG; Van Grootheest G; Van Os J; Vicente AM; Vieland VJ; Vincent JB; Visscher PM; Walsh CA; Wassink TH; Watson SJ; Weissman MM; Werge T; Wienker TF; Wijsman EM; Willemsen G; Williams N; Willsey AJ; Witt SH; Xu W; Young AH; Yu TW; Zammit S; Zandi PP; Zhang P; Zitman FG; Zoellner S; Devlin B; Kelsoe JR; Sklar P; Daly MJ; O'Donovan MC; Craddock N; Sullivan PF; Smoller JW; Kendler KS; Wray NR
  • Article: JAMA PSYCHIATRY. 2013;70(7):709-717
    Mataix-Cols D; Boman M; Monzani B; Ruck C; Serlachius E; Langstrom N; Lichtenstein P
  • Article: SCIENCE. 2013;340(6139):1467-1471
    Rietveld CA; Medland SE; Derringer J; Yang J; Esko T; Martin NW; Westra H-J; Shakhbazov K; Abdellaoui A; Agrawal A; Albrecht E; Alizadeh BZ; Amin N; Bamard J; Baumeister SE; Benke KS; Bielak LF; Boatman JA; Boyle PA; Davies G; De Leeuw C; Eklund N; Evans DS; Ferhmann R; Fischer K; Gieger C; Gjessing HK; Haegg S; Harris JR; Hayward C; Holzapfel C; Ibrahim-Verbaas CA; Ingelsson E; Jacobsson B; Joshi PK; Jugessur A; Kaakinen M; Kanoni S; Karjalainen J; Kolcic I; Kristiansson K; Kutalik Z; Lahti J; Lee SH; Lin P; Lind PA; Liu Y; Lohman K; Loitfelder M; McMahon G; Vidal PM; Meirelles O; Milani L; Myhre R; Nuotio M-L; Oldmeadow CJ; Petrovic KE; Peyrot WJ; Polasek O; Quaye L; Reinmaa E; Rice JP; Rizzi TS; Schmidt H; Schmidt R; Smith AV; Smith JA; Tanaka T; Terracciano A; van der Loos MJHM; Vitart V; Voelzke H; Wellmann J; Yu L; Zhao W; Allik J; Attia JR; Bandinelli S; Bastardot F; Beauchamp J; Bennett DA; Berger K; Bierut LJ; Boomsma DI; Bueltmann U; Campbell H; Chabris CF; Cherkas L; Chung MK; Cucca F; de Andrade M; De Jager PL; De Neve J-E; Deary IJ; Dedoussis GV; Deloukas P; Dimitriou M; Eiriksdottir G; Elderson MF; Eriksson JG; Evans DM; Faul JD; Ferrucci L; Garcia ME; Groenberg H; Guonason V; Hall P; Harris JM; Harris TB; Hastie ND; Heath AC; Hernandez DG; Hoffmann W; Hofman A; Holle R; Holliday EG; Hottenga J-J; Iacono WG; Illig T; Jaervelin M-R; Kaehoenen M; Kaprio J; Kirkpatrick RM; Kowgier M; Latvala A; Launer LJ; Lawlor DA; Lehtimaeki T; Li J; Lichtenstein P; Lichtner P; Liewald DC; Madden PA; Magnusson PKE; Maekinen TE; Masala M; McGue M; Metspalu A; Mielck A; Miller MB; Montgomery GW; Mukherjee S; Nyholt DR; Oostra BA; Palmer LJ; Palotie A; Penninx BWJH; Perola M; Peyser PA; Preisig M; Raeikkoenen K; Raitakari OT; Realo A; Ring SM; Ripatti S; Rivadeneira F; Rudan I; Rustichini A; Salomaa V; Sarin A-P; Schlessinger D; Scott RJ; Snieder H; St Pourcain B; Starr JM; Sul JH; Surakka I; Svento R; Teumer A; Tiemeier H; van Rooij FJA; Van Wagoner DR; Vartiainen E; Viikari J; Vollenweider P; Vonk JM; Waeber G; Weir DR; Wichmann H-E; Widen E; Willemsen G; Wilson JF; Wright AF; Conley D; Davey-Smith G; Franke L; Groenen PJF; Hofman A; Johannesson M; Kardia SLR; Krueger RF; Laibson D; Martin NG; Meyer MN; Posthuma D; Thurik AR; Timpson NJ; Uitterlinden AG; van Duijn CM; Visscher PM; Benjamin DJ; Cesarini D; Koellinger PD
  • Article: NEW ENGLAND JOURNAL OF MEDICINE. 2012;367(21):2006-2014
    Lichtenstein P; Halldner L; Zetterqvist J; Sjolander A; Serlachius E; Fazel S; Langstrom N; Larsson H
  • Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(11):1140-1150
    D'Onofrio BM; Rickert ME; Langstrom N; Donahue KL; Coyne CA; Larsson H; Ellingson JM; Van Hulle CA; Iliadou AN; Rathouz PJ; Lahey BB; Lichtenstein P
  • Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(11):1099-1103
    Sullivan PF; Magnusson C; Reichenberg A; Boman M; Dalman C; Davidson M; Fruchter E; Hultman CM; Lundberg M; Langstrom N; Weiser M; Svensson AC; Lichtenstein P
  • Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(1):46-52
    Lundstrom S; Chang Z; Rastam M; Gillberg C; Larsson H; Anckarsater H; Lichtenstein P
  • Article: MOLECULAR PSYCHIATRY. 2011;16(10):1039-1047
    Ronald A; Larsson H; Anckarsater H; Lichtenstein P
  • Article: NATURE GENETICS. 2011;43(10):969-976
    Ripke S; Sanders AR; Kendler KS; Levinson DF; Sklar P; Holmans PA; Lin D-Y; Duan J; Ophoff RA; Andreassen OA; Scolnick E; Cichon S; Clair DS; Corvin A; Gurling H; Werge T; Rujescu D; Blackwood DHR; Pato CN; Malhotra AK; Purcell S; Dudbridge F; Neale BM; Rossin L; Visscher PM; Posthuma D; Ruderfer DM; Fanous A; Stefansson H; Steinberg S; Mowry BJ; Golimbet V; De Hert M; Jonsson EG; Bitter I; Pietilainen OPH; Collier DA; Tosato S; Agartz I; Albus M; Alexander M; Amdur RL; Amin F; Bass N; Bergen SE; Black DW; Borglum AD; Brown MA; Bruggeman R; Buccola NG; Byerley WF; Cahn W; Cantor RM; Carr VJ; Catts SV; Choudhury K; Cloninger CR; Cormican P; Craddock N; Danoy PA; Datta S; De Haan L; Demontis D; Dikeos D; Djurovic S; Donnelly P; Donohoe G; Duong L; Dwyer S; Fink-Jensen A; Freedman R; Freimer NB; Friedl M; Georgieva L; Giegling I; Gill M; Glenthoj B; Godard S; Hamshere M; Hansen M; Hansen T; Hartmann AM; Henskens FA; Hougaard DM; Hultman CM; Ingason A; Jablensky AV; Jakobsen KD; Jay M; Juergens G; Kahn R; Keller MC; Kenis G; Kenny E; Kim Y; Kirov GK; Konnerth H; Konte B; Krabbendam L; Krasucki R; Lasseter VK; Laurent C; Lawrence J; Lencz T; Lerer FB; Liang K-Y; Lichtenstein P; Lieberman JA; Linszen DH; Lonnqvist J; Loughland CM; Maclean AW; Maher BS; Maier W; Mallet J; Malloy P; Mattheisen M; Mattingsdal M; McGhee KA; McGrath JJ; McIntosh A; McLean DE; McQuillin A; Melle I; Michie PT; Milanova V; Morris DW; Mors O; Mortensen PB; Moskvina V; Muglia P; Myin-Germeys I; Nertney DA; Nestadt G; Nielsen J; Nikolov I; Nordentoft M; Norton N; Noethen MM; O'Dushlaine CT; Olincy A; Olsen L; O'Neill FA; Orntoft TF; Owen MJ; Pantelis C; Papadimitriou G; Pato MT; Peltonen L; Petursson H; Pickard B; Pimm J; Pulver AE; Puri V; Quested D; Quinn EM; Rasmussen HB; Rethelyi JM; Ribble R; Rietschel M; Riley BP; Ruggeri M; Schall U; Schulze TG; Schwab SG; Scott RJ; Shi J; Sigurdsson E; Silverman JM; Spencer CCA; Stefansson K; Strange A; Strengman E; Stroup TS; Suvisaari J; Terenius L; Thirumalai S; Thygesen JH; Timm S; Toncheva D; van den Oord E; van Os J; van Winkel R; Veldink J; Walsh D; Wang AG; Wiersma D; Wildenauer DB; Williams HJ; Williams NM; Wormley B; Zammit S; Sullivan PF; O'Donovan MC; Daly MJ; Gejman PV
  • Article: NATURE GENETICS. 2011;43(10):977-983
    Psychiatric GWAS Consortium Bipolar Disorder Worki
  • Article: AMERICAN JOURNAL OF PSYCHIATRY. 2010;167(11):1357-1363
    Lichtenstein P; Carlstrom E; Rastam M; Gillberg C; Anckarsater H
  • Article: ARCHIVES OF GENERAL PSYCHIATRY. 2010;67(5):529-538
    D'Onofrio BM; Singh AL; Iliadou A; Lambe M; Hultman CM; Grann M; Neiderhiser JM; Langstrom N; Lichtenstein P
  • Article: NATURE. 2009;460(7256):748-752
    Purcell SM; Wray NR; Stone JL; Visscher PM; O'Donovan MC; Sullivan PF; Sklar P; Ruderfer DM; McQuillin A; Morris DW; O'Dushlaine CT; Corvin A; Holmans PA; Macgregor S; Gurling H; Blackwood DHR; Craddock NJ; Gill M; Hultman CM; Kirov GK; Lichtenstein P; Muir WJ; Owen MJ; Pato CN; Scolnick EM; St Clair D; Williams NM; Georgieva L; Nikolov I; Norton N; Williams H; Toncheva D; Milanova V; Thelander EF; Sullivan P; Kenny E; Quinn EM; Choudhury K; Datta S; Pimm J; Thirumalai S; Puri V; Krasucki R; Lawrence J; Quested D; Bass N; Crombie C; Fraser G; Kuan SL; Walker N; McGhee KA; Pickard B; Malloy P; Maclean AW; Van Beck M; Pato MT; Medeiros H; Middleton F; Carvalho C; Morley C; Fanous A; Conti D; Knowles JA; Ferreira CP; Macedo A; Azevedo MH; Kirby AN; Ferreira MAR; Daly MJ; Chambert K; Kuruvilla F; Gabriel SB; Ardlie K; Moran JL
  • Article: THE LANCET. 2009;373(9659):234-239
    Lichtenstein P; Yip BH; Bjork C; Pawitan Y; Cannon TD; Sullivan PF; Hultman CM
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Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

  • Professor, Genetisk epidemiologi, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2006-

Examina och utbildning

  • Docent, Genetisk epidemiologi, Karolinska Institutet, 1997
  • Doktor i medicinsk vetenskap i genetisk epidemiologi, Genetisk epidemiologi, Institutet för Miljömedicin, Karolinska Institutet, 1993
  • Filosofie kandidatexamen, Sociologi, Stockholms universitet, 1985

Uppdrag

  • Viceprefekt, Institutionen för medicinsk epidemiologi och biostatistik, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2022-
  • Programdirektor, Forskarutbildningen, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2019-
  • Prefekt, Institutionen för medicinsk epidemiologi och biostatistik, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2014-2017
  • President, Behavior Genetics Association, Behavior Genetics Association, 2012-2014
  • Sektionsansvarig, Svenska Tvillingregistret, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2006-2013

Priser och utmärkelser

  • James Shields Award For Lifetime Contributions To Twin Research, The International Society for Twin Studies (ISTS), 2011

Handledare

  • Jie Song, Bipolar disorder and lithium treatment: etiologies and consequences
  • Vide Ohlsson Gotby, Register-based studies of sex steroid hormones and psychiatric disorders.
  • Martin Cederlöf, Risks, correlates and consequences of the extended psychosis phenotype.
  • Amir Sariaslan, Exploring the causal nature of neighborhood influences on violent criminality, substance misuse and psychiatric morbidity.
  • Ralf Kuja-Halkola, Twin and family studies on the development of cognitive and externalizing problems.
  • Hans Walum, Genetic and hormonal influences on affiliative behavior in humans.
  • Jurgita Narusyte, Adolescent adjustment: the role of heritability and family environment.
  • Catherine Tuvblad, Genetic and environmental influences on antisocial behavior from childhood to emerging adulthood
  • Emma Nilsson, Genetic epidemiological studies of adverse pregnancy outcome and the role of schizophrenia
  • Henrik Larsson, Genetic and environmental factors in the development of externalizing symptoms from childhood to adolescence
  • Anastasia Iliadou, Genetic epidemiological approaches to the study of risk factors for cardiovascular diseases.
  • Linda Lindström, Familial studies on common cancers – a population based approach

Nyheter från KI

Kalenderhändelser från KI