Ourania Kostopoulou

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: BIOMEDICINE & PHARMACOTHERAPY. 2024;177:116993

Combined targeted therapy with PI3K and CDK4/6, or FGFR inhibitors show synergistic effects in a neuroblastoma spheroid culture model.

Lukoseviciute M; Need E; Holzhauser S; Dalianis T; Kostopoulou ON
Article: ANTICANCER RESEARCH. 2024;44(5):1863-1876

Curcumin Alone and Combined With PI3K Inhibitors Elicits Positive Effects on Oropharyngeal Cancer Cell Lines Regardless of HPV Status.

Lukoceviciute M; Zupancic M; Kostopoulou ON; Holzhauser S; Dalianis T
Article: ORAL ONCOLOGY. 2024;151:106749

Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival.

Zupancic M; Kostopoulou ON; Holzhauser S; Lukoseviciute M; Jylhä C; Marklund L; Näsman A; Sivars L; Dalianis T
Article: ONCOLOGY REPORTS. 2023;50(3):166

Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines.

Lukoseviciute M; Holzhauser S; Pappa E; Mandal T; Dalianis T; Kostopoulou ON
Article: ONCOLOGY REPORTS. 2023;49(6):125

Combination of PARP and WEE1 inhibitors in vitro: Potential for use in the treatment of SHH medulloblastoma.

Lukoseviciute M; Theodosopoulou A; Holzhauser S; Dalianis T; Kostopoulou ON
Article: CANCERS. 2023;15(7):1954

High Levels of FGF11 Correlate with Poor Survival in Patients with Human Papillomavirus (HPV)-Positive Oropharyngeal Squamous Cell Carcinoma.

Flon CHD; Haeggblom L; Holzhauser S; Kostopoulou ON; Zupancic M; Dalianis T; Munck-Wikland E; Marklund L; Näsman A
Article: CANCERS. 2022;15(1):93

Targeted Therapy with PI3K, PARP, and WEE1 Inhibitors and Radiotherapy in HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy while Effects with APR-246 Are Limited.

Byskata K; Lukoseviciute M; Tuti F; Zupancic M; Kostopoulou ON; Holzhauser S; Dalianis T
Article: VIRUSES-BASEL. 2022;14(7):1372

Targeted Therapy of HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy between CDK4/6, PI3K and Sometimes FGFR Inhibitors, but Rarely between PARP and WEE1 Inhibitors.

Kostopoulou ON; Zupancic M; Pont M; Papin E; Lukoseviciute M; Mikelarena BA; Holzhauser S; Dalianis T
Article: MICROORGANISMS. 2021;9(6):1137

Human Cytomegalovirus Reduces Endothelin-1 Expression in Both Endothelial and Vascular Smooth Muscle Cells.

Yaiw K-C; Mohammad A-A; Taher C; Cui HL; Costa H; Kostopoulou ON; Jung M; Assinger A; Wilhelmi V; Yang J; Strååt K; Rahbar A; Pernow J; Söderberg-Nauclér C
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(7):3664

Heterogeneities in Cell Cycle Checkpoint Activation Following Doxorubicin Treatment Reveal Targetable Vulnerabilities in TP53 Mutated Ultra High-Risk Neuroblastoma Cell Lines.

Ödborn Jönsson L; Sahi M; Lopez-Lorenzo X; Keller FL; Kostopoulou ON; Herold N; Ährlund-Richter L; Shirazi Fard S
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2021;58(2):211-225

Effects of PI3K and FGFR inhibitors alone and in combination, and with/without cytostatics in childhood neuroblastoma cell lines.

Holzhauser S; Lukoseviciute M; Papachristofi C; Vasilopoulou C; Herold N; Wickström M; Kostopoulou ON; Dalianis T
Article: FRONTIERS IN ONCOLOGY. 2021;11:640490

Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations.

Holzhauser S; Wild N; Zupancic M; Ursu RG; Bersani C; Näsman A; Kostopoulou ON; Dalianis T
Article: FRONTIERS IN ONCOLOGY. 2021;11:748657

Targeting PI3K, FGFR, CDK4/6 Signaling Pathways Together With Cytostatics and Radiotherapy in Two Medulloblastoma Cell Lines.

Lukoseviciute M; Maier H; Poulou-Sidiropoulou E; Rosendahl E; Holzhauser S; Dalianis T; Kostopoulou ON
Article: BIOLOGY-BASEL. 2020;9(3):E44-44

Human Cytomegalovirus Infection Induces High Expression of Prolactin and Prolactin Receptors in Ovarian Cancer.

Rahbar A; AlKharusi A; Costa H; Pantalone MR; Kostopoulou ON; Cui HL; Carlsson J; Rådestad AF; Söderberg-Naucler C; Norstedt G
Article: ANTICANCER RESEARCH. 2020;40(1):53-66

Targeting Fibroblast Growth Factor Receptor (FGFR) and Phosphoinositide 3-kinase (PI3K) Signaling Pathways in Medulloblastoma Cell Lines.

Holzhauser S; Lukoseviciute M; Andonova T; Ursu RG; Dalianis T; Wickström M; Kostopoulou ON
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2019;55(6):1372-1384

Analyses of FGFR3 and PIK3CA mutations in neuroblastomas and the effects of the corresponding inhibitors on neuroblastoma cell lines.

Kostopoulou ON; Holzhauser S; Lange BKA; Ohmayer A; Andonova T; Bersani C; Wickström M; Dalianis T
Article: ONCOLOGY LETTERS. 2019;18(6):6249-6260

In vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines.

Holzhauser S; Kostopoulou ON; Ohmayer A; Lange BKA; Ramqvist T; Andonova T; Bersani C; Wickström M; Dalianis T
Article: TRANSLATIONAL ONCOLOGY. 2018;11(6):1292-1300

Impact of Human Cytomegalovirus Infection and its Immune Response on Survival of Patients with Ovarian Cancer.

Rådestad AF; Estekizadeh A; Cui HL; Kostopoulou ON; Davoudi B; Hirschberg AL; Carlson J; Rahbar A; Söderberg-Naucler C
Article: INTERNATIONAL JOURNAL OF CANCER. 2018;142(6):1266-1276

Glucocorticoids promote a glioma stem cell-like phenotype and resistance to chemotherapy in human glioblastoma primary cells: Biological and prognostic significance.

Kostopoulou ON; Mohammad A-A; Bartek J; Winter J; Jung M; Stragliotto G; Söderberg-Nauclér C; Landázuri N
Article: ONCOTARGET. 2017;8(57):96536-96552

Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.

Kostopoulou ON; Wilhelmi V; Raiss S; Ananthaseshan S; Lindström MS; Bartek J; Söderberg-Naucler C
Article: ONCOTARGET. 2016;7(30):47221-47231

Human cytomegalovirus may promote tumour progression by upregulating arginase-2.

Costa H; Xu X; Overbeek G; Vasaikar S; Patro CPK; Kostopoulou ON; Jung M; Shafi G; Ananthaseshan S; Tsipras G; Davoudi B; Mohammad A-A; Lam H; Strååt K; Wilhelmi V; Shang M; Tegner J; Tong JC; Wong KT; Söderberg-Naucler C; Yaiw K-C
Article: JOURNAL OF GENERAL VIROLOGY. 2015;96(12):3598-3612

Direct infection of primary endothelial cells with human cytomegalovirus prevents angiogenesis and migration.

Gustafsson RKL; Jeffery HC; Yaiw K-C; Wilhelmi V; Kostopoulou ON; Davoudi B; Rahbar A; Benard M; Renné T; Söderberg-Nauclér C; Butler LM
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2015;23(13):3163-3174

Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates.

Magoulas GE; Kostopoulou ON; Garnelis T; Athanassopoulos CM; Kournoutou GG; Leotsinidis M; Dinos GP; Papaioannou D; Kalpaxis DL
Article: JOURNAL OF ENDOUROLOGY. 2015;29(5):580-589

Evaluation of the distribution of Paclitaxel by immunohistochemistry and nuclear magnetic resonance spectroscopy after the application of a drug-eluting balloon in the porcine ureter.

Liourdi D; Kallidonis P; Kyriazis I; Tsamandas A; Karnabatidis D; Kitrou P; Spyroulias GA; Kostopoulou ON; Marousis K; Kalpaxis DL; Goumenos DS; Liatsikos E
Article: PLOS ONE. 2015;10(8):e0134526

Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.

Kostopoulou ON; Magoulas GE; Papadopoulos GE; Mouzaki A; Dinos GP; Papaioannou D; Kalpaxis DL
Article: NUCLEIC ACIDS RESEARCH. 2014;42(13):8621-8634

Conjugation with polyamines enhances the antibacterial and anticancer activity of chloramphenicol.

Kostopoulou ON; Kouvela EC; Magoulas GE; Garnelis T; Panagoulias I; Rodi M; Papadopoulos G; Mouzaki A; Dinos GP; Papaioannou D; Kalpaxis DL
Article: PHARMAZIE. 2013;68(7):616-621

Clindamycin binding to ribosomes revisited: foot printing and computational detection of two binding sites within the peptidyl transferase center.

Kostopoulou ON; Papadopoulos G; Kouvela EC; Kalpaxis DL
Article: NUCLEIC ACIDS RESEARCH. 2012;40(11):5078-5087

Investigating the entire course of telithromycin binding to Escherichia coli ribosomes.

Kostopoulou ON; Petropoulos AD; Dinos GP; Choli-Papadopoulou T; Kalpaxis DL
Journal article: OPEN ENZYME INHIBITION JOURNAL. 2011;4(1):1-10

Insights into the Chloramphenicol Inhibition Effect on Peptidyl Transferase Activity, Using Two New Analogs of the Drug

Kostopoulou ON
Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2010;35(3):235-239

Dissecting the ribosomal inhibition mechanism of a new ketolide carrying an alkyl-aryl group at C-13 of its lactone ring.

Krokidis MG; Kostopoulou ON; Kalpaxis DL; Dinos GP
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Alla övriga publikationer

Review: ANTICANCER RESEARCH. 2023;43(9):3829-3839

New Approaches Towards Targeted Therapy for Childhood Neuroblastoma.

Dalianis T; Lukoseviciute M; Holzhauser S; Kostopoulou ON
Review: VIRUSES-BASEL. 2021;13(5):910

Prognostic Markers and Driver Genes and Options for Targeted Therapy in Human-Papillomavirus-Positive Tonsillar and Base-of-Tongue Squamous Cell Carcinoma.

Näsman A; Holzhauser S; Kostopoulou ON; Zupancic M; Ährlund-Richter A; Du J; Dalianis T
Review: ANTICANCER RESEARCH. 2021;41(4):1715-1726

New Approaches in Targeted Therapy for Medulloblastoma in Children.

Maier H; Dalianis T; Kostopoulou ON

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