Nicole Marquardt

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: MICROORGANISMS. 2025;13(5):1077
Dysregulated Adaptive Immune Responses to SARS-CoV-2 in Immunocompromised Individuals
Danes NM; Brownlie D; Folkman R; Nordlander A; Blom K; Varnaite R; Niessl J; Lindsjo OK; Soderholm S; Akber M; Chen P; Buggert M; Brave A; Klingstrom J; Nowak P; Marquardt N; Sonden K; Blennow O; Gredmark-Russ S
Article: GENES AND IMMUNITY. 2025;26(1):70-74
The HLA-B-21 M/T dimorphism associates with disease severity in COVID-19
Strunz B; Momayyezi P; Bilev E; Muvva JR; Chen P; Bister J; Schaffer M; Akber M; Cornillet M; Horowitz A; Malmberg K-J; Rooyackers O; Aleman S; Ljunggren H-G; Bjorkstrom NK; Stralin K; Hammer Q
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2025;55(2):e202451150
Distinct Tissue-Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells
Rodahl IE; Ivarsson MA; Loh L; Mold JE; Westgren M; Friberg D; Mjosberg J; Bjorkstrom NK; Marquardt N; Nixon DF; Michaelsson J
Article: PLOS PATHOGENS. 2024;20(12):e1012755
Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness
Bilev E; Wild N; Momayyezi P; Sala BM; Sun R; Sandalova T; Marquardt N; Ljunggren H-G; Achour A; Hammer Q
Article: SCIENCE IMMUNOLOGY. 2024;9(99):eadn2362
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
Kammann T; Cai C; Sekine T; Mouchtaridi E; Boulouis C; Nilsen V; Ballesteros OR; Mueller TR; Gao Y; Raineri EJM; Mily A; Adamo S; Constantz C; Niessl J; Weigel W; Kokkinou E; Stamper C; Marchalot A; Bassett J; Ferreira S; Rodahl I; Wild N; Brownlie D; Tibbitt C; Mak JYW; Fairlie DP; Leeansyah E; Michaelsson J; Marquardt N; Mjosberg J; Jorns C; Buggert M; Sandberg JK
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: NATURE IMMUNOLOGY. 2024;25(8):1445-1459
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Netskar H; Pfefferle A; Goodridge JP; Sohlberg E; Dufva O; Teichmann SA; Brownlie D; Michaelsson J; Marquardt N; Clancy T; Horowitz A; Malmberg K-J
Article: ONCOIMMUNOLOGY. 2023;12(1):2233402
Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8⁺ T cells towards the center of human lung tumors
Brownlie D; von Kries A; Valenzano G; Wild N; Yilmaz E; Safholm J; Al-Ameri M; Alici E; Ljunggren H-G; Schliemann I; Aricak O; de Flon FH; Michaelsson J; Marquardt N
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
The Karolinska KI/K COVID-19 immune atlas: An open resource for immunological research and educational purposes
Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
Article: CELL REPORTS MEDICINE. 2022;3(2):100508
Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma
Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellstrom K; Liwing J; Gustafsson C; Mansson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:834862
Comparison of Lung-Homing Receptor Expression and Activation Profiles on NK Cell and T Cell Subsets in COVID-19 and Influenza
Brownlie D; Rodahl I; Varnaite R; Asgeirsson H; Glans H; Falck-Jones S; Vangeti S; Buggert M; Ljunggren H-G; Michaelsson J; Gredmark-Russ S; Smed-Sorensen A; Marquardt N
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(11):e2016580118
Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood
Brownlie D; Scharenberg M; Mold JE; Hard J; Kekalainen E; Buggert M; Nguyen S; Wilson JN; Al-Ameri M; Ljunggren H-G; Marquardt N; Michaelsson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: IMMUNITY. 2021;54(2):259-275.e7
Distinct developmental pathways from blood monocytes generate human lung macrophage diversity
Evren E; Ringqvist E; Tripathi KP; Sleiers N; Rives IC; Alisjahbana A; Gao Y; Sarhan D; Halle T; Sorini C; Lepzien R; Marquardt N; Michaelsson J; Smed-Sorensen A; Botling J; Karlsson MCI; Villablanca EJ; Willinger T
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:752104
CD5 Surface Expression Marks Intravascular Human Innate Lymphoid Cells That Have a Distinct Ontogeny and Migrate to the Lung
Alisjahbana A; Gao Y; Sleiers N; Evren E; Brownlie D; von Kries A; Jorns C; Marquardt N; Michaelsson J; Willinger T
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: NATURE COMMUNICATIONS. 2019;10(1):3897
NK cells are activated and primed for skin-homing during acute dengue virus infection in humans
Zimmer CL; Cornillet M; Sola-Riera C; Cheung K-W; Ivarsson MA; Lim MQ; Marquardt N; Leo Y-S; Lye DC; Klingstrom J; MacAry PA; Ljunggren H-G; Rivino L; Bjorkstrom NK
Article: NATURE COMMUNICATIONS. 2019;10(1):3841
Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells
Marquardt N; Kekalainen E; Chen P; Lourda M; Wilson JN; Scharenberg M; Bergman P; Al-Ameri M; Hard J; Mold JE; Ljunggren H-G; Michaelsson J
Article: JOURNAL OF HEPATOLOGY. 2019;71(2):301-312
Chronic hepatitis delta virus infection leads to functional impairment and severe loss of MAIT cells
Dias J; Hengst J; Parrot T; Leeansyah E; Lunemann S; Malone DFG; Hardtke S; Strauss O; Zimmer CL; Berglin L; Schirdewahn T; Ciesek S; Marquardt N; von Hahn T; Manns MP; Cornberg M; Ljunggren H-G; Wedemeyer H; Sandberg JK; Bjorkstrom NK
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1116
Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells
Scharenberg M; Vangeti S; Kekalainen E; Bergman P; Al-Ameri M; Johansson N; Sonden K; Falck-Jones S; Farnert A; Ljunggren H-G; Michaelsson J; Smed-Sorensen A; Marquardt N
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1321-1330.e4
Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69^-CD56^dim cells
Marquardt N; Kekalainen E; Chen P; Kvedaraite E; Wilson JN; Ivarsson MA; Mjosberg J; Berglin L; Safholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Svensson M; Dahlen B; Dahlen S-E; Ljunggren H-G; Michaelsson J
Article: MUCOSAL IMMUNOLOGY. 2017;10(2):322-331
Composition and dynamics of the uterine NK cell KIR repertoire in menstrual blood
Ivarsson MA; Stiglund N; Marquardt N; Westgren M; Gidlof S; Bjorkstrom NK
Article: IMMUNITY. 2017;46(2):287-300
CD49a Expression Defines Tissue-Resident CD8⁺ T Cells Poised for Cytotoxic Function in Human Skin
Cheuk S; Schlums H; Serezal IG; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Hoog C; Tjernlund A; Michaelsson J; Folkersen L; Mjosberg J; Blomqvist L; Ehrstrom M; Stahle M; Bryceson YT; Eidsmo L
Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3069-3075
Fetal CD103⁺ IL-17-Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid
Marquardt N; Ivarsson MA; Sundstrom E; Akesson E; Martini E; Eidsmo L; Mjosberg J; Friberg D; Kublickas M; Ek S; Tegerstedt G; Seiger A; Westgren M; Michaelsson J
Article: JOURNAL OF IMMUNOLOGY. 2015;195(7):3262-3272
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education
Marquardt N; Ivarsson MA; Blom K; Gonzalez VD; Braun M; Falconer K; Gustafsson R; Fogdell-Hahn A; Sandberg JK; Michaelsson J
Article: JOURNAL OF IMMUNOLOGY. 2015;194(6):2467-2471
Cutting Edge: Identification and Characterization of Human Intrahepatic CD49a⁺ NK Cells
Marquardt N; Beziat V; Nystrom S; Hengst J; Ivarsson MA; Kekalainen E; Johansson H; Mjosberg J; Westgren M; Lankisch TO; Wedemeyer H; Ellis EC; Ljunggren H-G; Michaelsson J; Bjorkstrom NK
Article: FRONTIERS IN IMMUNOLOGY. 2014;5:662
Human umbilical cord-derived mesenchymal stem cells utilize activin-A to suppress interferon-γ production by natural killer cells
Chatterjee D; Marquardt N; Tufa DM; Hatlapatka T; Hass R; Kasper C; von Kaisenberg C; Schmidt RE; Jacobs R
Article: CELL COMMUNICATION AND SIGNALING. 2014;12:63
Role of gamma-secretase in human umbilical-cord derived mesenchymal stem cell mediated suppression of NK cell cytotoxicity
Chatterjee D; Marquardt N; Tufa DM; Beauclair G; Low HZ; Hatlapatka T; Hass R; Kasper C; von Kaisenberg C; Schmidt RE; Jacobs R
Article: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(9):3889-3901
Differentiation and functional regulation of human fetal NK cells
Ivarsson MA; Loh L; Marquardt N; Kekalainen E; Berglin L; Bjorkstrom NK; Westgren M; Nixon DF; Michaelsson J
Article: BRAIN BEHAVIOR AND IMMUNITY. 2011;25(6):1233-1241
Human CD8⁺ T cells and NK cells express and secrete S100B upon stimulation
Steiner J; Marquardt N; Pauls I; Schiltz K; Rahmoune H; Bahn S; Bogerts B; Schmidt RE; Jacobs R
Article: TISSUE ENGINEERING PART C-METHODS. 2011;17(4):485-493
Optimization of Culture Conditions for the Expansion of Umbilical Cord-Derived Mesenchymal Stem or Stromal Cell-Like Cells Using Xeno-Free Culture Conditions
Hatlapatka T; Moretti P; Lavrentieva A; Hass R; Marquardt N; Jacobs R; Kasper C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2010;40(5):1428-1439
Murine CXCR3⁺CD27^bright NK cells resemble the human CD56^bright NK-cell population
Marquardt N; Wilk E; Pokoyski C; Schmidt RE; Jacobs R
Article: JOURNAL OF STEM CELLS AND REGENERATIVE MEDICINE. 2010;6(2):101-102
Shaping the microenvironment of umbilical cord-derived mesenchymal stem cell-like cells.
Hatlapatka T; Lavrentieva A; Moretti P; Hass R; Marquardt N; Jacobs R; Kasper C
Article: ARTHRITIS & RHEUMATOLOGY. 2009;60(12):3563-3571
Depletion of Functionally Active CD20+T Cells by Rituximab Treatment
Wilk E; Witte T; Marquardt N; Horvath T; Kalippke K; Scholz K; Wilke N; Schmidt RE; Jacobs R
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Anställningar

Senior Forskningsspecialist, Medicin, Huddinge, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Immunologi, Karolinska Institutet, 2025
PhD, Immunology, Characterization of immunoregulatory NK cells, non-Treg T cells and mesenchymal stem cells, Department of Clinical Immunology and Rheumatology, Hannover Medical School, 2011

Artiklar

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI