Nanna Fyhrquist

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;156(1):24-40.e4
Endotypes of atopic dermatitis.
Fyhrquist N; Yang Y; Karisola P; Alenius H
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;:S0091-6749(25)00570-6
Dissecting key contributions of T<sub>H</sub>2 and T<sub>H</sub>17 cytokines to atopic dermatitis pathophysiology.
Meesters LD; Roubroeks JAY; Gerritsen A; Velthuijs N; Klijnhout JA; Laberthonnière C; van Vlijmen-Willems IM; Hübenthal M; Rodijk-Olthuis D; Peters RHW; Rikken G; Szymczak S; Fyhrquist N; Alenius H; Weidinger S; Smits JPH; Mhlanga M; Zhou H; Niehues H; van den Bogaard EH
Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;192(5):931-933
Taxonomic and functional profiling of skin microbiome in psoriasis
Sinkko H; Olah P; Yang Y; Maia G; Barrientos-Somarribas M; Radai Z; Maenpaa K; Soratto T; Salava A; Lauerma A; Barker J; Ranki A; Homey B; Andersson B; Fyhrquist N; Alenius H; MAARS Consortium J
Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2024;144(12):s289
352 Evaluation of allergenic properties and uptake of cobalt nanoparticles in human skin; a comprehensive transcriptomic analysis and skin permeation assessment
Werner P; Schaier M; Braun G; Julander A; Midander K; Isaksson M; Köllensperger G; Wisgrill L; Fyhrquist N
Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2024;144(12):s279
292 Data-driven modeling of cutaneous ecosystems in homeostasis and inflammation
Olah P; Radai Z; Smits J; Gomez-Casado C; Consortium E; Sinkko H; Fyhrquist N; Andersson B; Alenius H; Homey B
Article: ALLERGY. 2024;79(11):3062-3081
Network analysis reveals age- and virus-specific circuits in nasal epithelial cells of extremely premature infants
Wisgrill L; Martens A; Kasbauer R; Eigenschink M; Pummer L; Redlberger-Fritz M; Vegvari A; Warth B; Berger A; Fyhrquist N; Alenius H
Article: EBIOMEDICINE. 2024;105:105222
Exploratory multi-omics analysis reveals host-microbe interactions associated with disease severity in psoriatic skin
Yang Y; Olah P; Radai Z; Maia G; Salava A; Salo V; Barker J; Lauerma A; Andersson B; Homey B; Fyhrquist N; Alenius H
Journal article: JACS AU. 2024;4(6):2197-2210
MeXpose-A Modular Imaging Pipeline for the Quantitative Assessment of Cellular Metal Bioaccumulation
Braun G; Schaier M; Werner P; Theiner S; Zanghellini J; Wisgrill L; Fyhrquist N; Koellensperger G
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):64
Integrative network analysis suggests prioritised drugs for atopic dermatitis
Federico A; Mobus L; Al-Abdulraheem Z; Pavel A; Fortino V; del Giudice G; Alenius H; Fyhrquist N; Greco D
Journal article: OPEN RESEARCH EUROPE. 2024;:194
Unmasking metabolic disruptors: The NEMESIS project's quest for Novel Biomarkers, Evidence on Adverse Effects, and Efficient Methodologies
Hakomäki H; Pitkänen S; Levonen A-L; Honkakoski P; Greco D; Saarimäki LA; Viegas S; Godinho C; Fyhrquist N; Wincent E; Lauschke V; Hukkanen J; Hakkola J; Vallier L; Fortino V; Afantitis A; Sawatani T; Guzman T; Cnop M; Nawrot T; Harlid S; Vinnars M-T; Tardon A; Grimalt J; Küblbeck J; Rysä J
Journal article: CURRENT OPINION IN TOXICOLOGY. 2023;35:100420
Host-microbiome interactions in atopic and allergic diseases
Fyhrquist N; Werner P; Alenius H
Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(5):s178
1038 Host transcriptomes that define microbiota during cutaneous homeostasis and inflammation
Olah P; Radai Z; Smits JP; Gomez-Casado C; Consortium EM; Sinkko H; Fyhrquist N; Andersson B; Alenius H; Homey B
Article: BRITISH JOURNAL OF DERMATOLOGY. 2023;188(2):278-287
Cobalt nanoparticles cause allergic contact dermatitis in humans
Midander K; Werner P; Isaksson M; Wisgrill L; Liden C; Fyhrquist N; Julander A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2022;52(8):929-941
Bet v 1 triggers antiviral-type immune signalling in birch-pollen-allergic individuals
Wisgrill L; Fyhrquist N; Ndika J; Paalanen L; Berger A; Laatikainen T; Karisola P; Haahtela T; Alenius H
Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 2022;106(3):132-140
Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation
Olah P; Szlavicz E; Kuchner M; Nemmer J; Zeeuwen P; Lefevre-Utile A; Fyhrquist N; Prast-Nielsen S; Skoog T; Serra A; Rodriguez E; Raap U; Meller S; Gyulai R; Hupe P; Kere J; Levi-Schaffer F; Tsoka S; Alexander H; Nestle FO; Schroeder JM; Weidinger S; van den Bogaard E; Soumelis V; Greco D; Barker J; Lauerma A; Ranki A; Andersson B; Alenius H; Homey B
Article: ALLERGY. 2022;77(5):1486-1498
Transcriptome-based identification of novel endotypes in adult atopic dermatitis
Lefevre-Utile A; Saichi M; Olah P; Delord M; Homey B; Soumelis V
Article: FRONTIERS IN ALLERGY. 2022;3:878862
Epigenetic Differences in Long Non-coding RNA Expression in Finnish and Russian Karelia Teenagers With Contrasting Risk of Allergy and Asthma
Ndika J; Karisola P; Lahti V; Fyhrquist N; Laatikainen T; Haahtela T; Alenius H
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2021;9(5):1892-1901.e1
A Randomized, Open-Label Trial of Hen's Egg Oral Immunotherapy: Efficacy and Humoral Immune Responses in 50 Children
Palosuo K; Karisola P; Savinko T; Fyhrquist N; Alenius H; Makela MJ
Article: ALLERGY. 2021;76(4):1173-1187
Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites
Ottman N; Barrientos-Somarribas M; Fyhrquist N; Alexander H; Wisgrill L; Olah P; Tsoka S; Greco D; Levi-Schaffer F; Soumelis V; Schroeder JM; Kere J; Nestle FO; Barker J; Ranki A; Lauerma A; Homey B; Andersson B; Alenius H
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(3):1031-1040
Shared DNA methylation signatures in childhood allergy: The MeDALL study
Xu C-J; Gruzieva O; Qi C; Esplugues A; Gehring U; Bergstroem A; Mason D; Chatzi L; Porta D; Carlsen KCL; Baiz N; Madore A-M; Alenius H; van Rijkom B; Jankipersadsing SA; van der Vlies P; Kull I; van Hage M; Bustamante M; Lertxundi A; Torrent M; Santorelli G; Fantini MP; Hovland V; Pesce G; Fyhrquist N; Laatikainen T; Nawijn MC; Li Y; Wijmenga C; Netea MG; Bousquet J; Anto JM; Laprise C; Haahtela T; Annesi-Maesano I; Carlsen K-H; Gori D; Kogevinas M; Wright J; Soederhaell C; Vonk JM; Sunyer J; Melen E; Koppelman GH
Article: ALLERGY. 2021;76(3):804-815
Integrative transcriptome analysis deciphers mechanisms of nickel contact dermatitis
Wisgrill L; Werner P; Jalonen E; Berger A; Lauerma A; Alenius H; Fyhrquist N
Article: JOURNAL OF IMMUNOTOXICOLOGY. 2021;18(1):74-84
Impact of mono-culture vs. Co-culture of keratinocytes and monocytes on cytokine responses induced by important skin sensitizers
Karri V; Liden C; Fyhrquist N; Hogberg J; Karlsson HL
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:704633
Integrative Transcriptomics Reveals Activation of Innate Immune Responses and Inhibition of Inflammation During Oral Immunotherapy for Egg Allergy in Children
Karisola P; Palosuo K; Hinkkanen V; Wisgrill L; Savinko T; Fyhrquist N; Alenius H; Makela MJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(52):33474-33485
Machine-learning-driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
Fortino V; Wisgrill L; Werner P; Suomela S; Linder N; Jalonen E; Suomalainen A; Marwah V; Kero M; Pesonen M; Lundin J; Lauerma A; Aalto-Korte K; Greco D; Alenius H; Fyhrquist N
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2020;50(10):1148-1158
Immune-microbiota interaction in Finnish and Russian Karelia young people with high and low allergy prevalence
Ruokolainen L; Fyhrquist N; Laatikainen T; Auvinen P; Fortino V; Scala G; Jousilahti P; Karisola P; Vendelin J; Karkman A; Markelova O; Makela MJ; Lehtimaki S; Ndika J; Ottman N; Paalanen L; Paulin L; Vartiainen E; von Hertzen L; Greco D; Haahtela T; Alenius H
Article: ALLERGOLOGIE. 2020;43(4):153-163
The roadmap for the Allergology specialty and allergy care in Europe and adjacent countries. An EAACI position paper
Fyhrquist N; Werfel T; Bilo MB; Muelleneisen N; van Wijk RG
Article: SCIENTIFIC REPORTS. 2019;9(1):20069
An optimized, robust and reproducible protocol to generate well-differentiated primary nasal epithelial models from extremely premature infants
Martens A; Amann G; Schmidt K; Gaupmann R; Boehm B; Dehlink E; Szepfalusi Z; Foerster-Waldl E; Berger A; Fyhrquist N; Alenius H; Wisgrill L
Article: NATURE COMMUNICATIONS. 2019;10(1):4703
Microbe-host interplay in atopic dermatitis and psoriasis
Fyhrquist N; Muirhead G; Prast-Nielsen S; Jeanmougin M; Olah P; Skoog T; Jules-Clement G; Feld M; Barrientos-Somarribas M; Sinkko H; van den Bogaard EH; Zeeuwen PLJM; Rikken G; Schalkwijk J; Niehues H; Daeubener W; Eller SK; Alexander H; Pennino D; Suomela S; Tessas I; Lybeck E; Baran AM; Darban H; Gangwar RS; Gerstel U; Jahn K; Karisola P; Yan L; Hansmann B; Katayama S; Meller S; Bylesjo M; Hupe P; Levi-Schaffer F; Greco D; Ranki A; Schroeder JM; Barker J; Kere J; Tsoka S; Lauerma A; Soumelis V; Nestle FO; Homeyl B; Andersson B; Alenius H
Article: GASTROENTEROLOGY CLINICS OF NORTH AMERICA. 2019;48(3):377-387
The Human Microbiota and Its Relationship with Allergies
Fyhrquist N
Article: CLINICAL INFECTIOUS DISEASES. 2019;68(11):1904-1910
Cutavirus DNA in Malignant and Nonmalignant Skin of Cutaneous T-Cell Lymphoma and Organ Transplant Patients but Not of Healthy Adults
Vaisanen E; Fu Y; Koskenmies S; Fyhrquist N; Wang Y; Keinonen A; Makisalo H; Vakeva L; Pitkanen S; Ranki A; Hedman K; Soederlund-Venermo M
Article: TRANSPLANT INTERNATIONAL. 2019;32(5):516-522
Occurrence of newly discovered human polyomaviruses in skin of liver transplant recipients and their relation with squamous cell carcinoma in situ and actinic keratosis - a single-center cohort study
Wang Y; Keinonen A; Koskenmies S; Pitkanen S; Fyhrquist N; Sadeghi M; Makisalo H; Soderlund-Venermo M; Hedman K
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(3):1198-1206.e12
Soil exposure modifies the gut microbiota and supports immune tolerance in a mouse model
Ottman N; Ruokolainen L; Suomalainen A; Sinkko H; Karisola P; Lehtimaki J; Lehto M; Hanski I; Alenius H; Fyhrquist N
Article: LANCET RESPIRATORY MEDICINE. 2018;6(5):379-388
DNA methylation in childhood asthma: an epigenome-wide meta-analysis
Xu C-J; Soderhall C; Bustamante M; Baiz N; Gruzieva O; Gehring U; Mason D; Chatzi L; Basterrechea M; Llop S; Torrent M; Forastiere F; Fantini MP; Carlsen KCL; Haahtela T; Morin A; Kerkhof M; Merid SK; van Rijkom B; Jankipersadsing SA; Bonder MJ; Ballereau S; Vermeulen CJ; Aguirre-Gamboa R; de Jongste JC; Smit HA; Kumar A; Pershagen G; Guerra S; Garcia-Aymerich J; Greco D; Reinius L; McEachan RRC; Azad R; Hovland V; Mowinckel P; Alenius H; Fyhrquist N; Lemonnier N; Pellet J; Auffray C; van der Vlies P; van Diemen CC; Li Y; Wijmenga C; Netea MG; Moffatt MF; Cookson WOCM; Anto JM; Bousquet J; Laatikainen T; Laprise C; Carlsen K-H; Gori D; Porta D; Iniguez C; Bilbao JR; Kogevinas M; Wright J; Brunekreef B; Kere J; Nawijn MC; Annesi-Maesano I; Sunyer J; Melen E; Koppelman GH
Article: EXPERIMENTAL DERMATOLOGY. 2018;27(1):30-36
Isotretinoin and lymecycline treatments modify the skin microbiota in acne
Kelhala H-L; Aho VTE; Fyhrquist N; Pereira PAB; Kubin ME; Paulin L; Palatsi R; Auvinen P; Tasanen K; Lauerma A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;140(5):1288-1298
Epithelial proteome profiling suggests the essential role of interferon-inducible proteins in patients with allergic rhinitis
Ndika J; Airaksinen L; Suojalehto H; Karisola P; Fyhrquist N; Puustinen A; Alenius H
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(5):665-674
Significant disparities in allergy prevalence and microbiota between the young people in Finnish and Russian Karelia
Ruokolainen L; Paalanen L; Karkman A; Laatikainen T; von Hertzen L; Vlasoff T; Markelova O; Masyuk V; Auvinen P; Paulin L; Alenius H; Fyhrquist N; Hanski I; Makela MJ; Zilber E; Jousilahti P; Vartiainen E; Haahtela T
Article: ANNALES ZOOLOGICI FENNICI. 2017;54(1-4):39-49
Holistic view on health: two protective layers of biodiversity
Ruokolainen L; Lehtimaki J; Karkman A; Haahtela T; von Hertzen L; Fyhrquist N
Article: JOURNAL OF INNATE IMMUNITY. 2017;9(1):65-82
Hemin and Cobalt Protoporphyrin Inhibit NLRP3 Inflammasome Activation by Enhancing Autophagy: A Novel Mechanism of Inflammasome Regulation
Nurmi K; Kareinen I; Virkanen J; Rajamaki K; Kouri V-P; Vaali K; Levonen A-L; Fyhrquist N; Matikainen S; Kovanen PT; Eklund KK
Article: EXPERIMENTAL DERMATOLOGY. 2016;25(6):477-478
Isotretinoin treatment reduces acne lesions but not directly lesional acne inflammation
Kelhala H-L; Fyhrquist N; Palatsi R; Lehtimaki S; Ayrynen JPV; Kubin ME; Kallioinen M; Alenius H; Tasanen K; Lauerma A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2015;45(5):891-901
Hunt for the origin of allergy - comparing the Finnish and Russian Karelia
Haahtela T; Laatikainen T; Alenius H; Auvinen P; Fyhrquist N; Hanski I; von Hertzen L; Jousilahti P; Kosunen TU; Markelova O; Makela MJ; Pantelejev V; Uhanov M; Zilber E; Vartiainen E
Article: ALLERGY. 2015;70(2):195-202
Green areas around homes reduce atopic sensitization in children
Ruokolainen L; von Hertzen L; Fyhrquist N; Laatikainen T; Lehtomaki J; Auvinen P; Karvonen AM; Hyvarinen A; Tillmann V; Niemela O; Knip M; Haahtela T; Pekkanen J; Hanski I
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(12):2928-2937
Complex 2B4 Regulation of Mast Cells and Eosinophils in Murine Allergic Inflammation
Elishmereni M; Fyhrquist N; Gangwar RS; Lehtimaki S; Alenius H; Levi-Schaffer F
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(6):1301-1309.e11
Acinetobacter species in the skin microbiota protect against allergic sensitization and inflammation
Fyhrquist N; Ruokolainen L; Suomalainen A; Lehtimaki S; Veckman V; Vendelin J; Karisola P; Lehto M; Savinko T; Jarva H; Kosunen TU; Corander J; Auvinen P; Paulin L; von Hertzen L; Laatikainen T; Makela M; Haahtela T; Greco D; Hanski I; Alenius H
Article: IMMUNITY INFLAMMATION AND DISEASE. 2014;2(3):162-165
Advantages of Foxp3⁺ regulatory T cell depletion using DEREG mice
Mayer CT; Lahl K; Milanez-Almeida P; Watts D; Dittmer U; Fyhrquist N; Huehn J; Kopf M; Kretschmer K; Rouse B; Sparwasser T
Article: PLOS ONE. 2014;9(9):e107801
A Robust and Accurate Method for Feature Selection and Prioritization from Multi-Class OMICs Data
Fortino V; Kinaret P; Fyhrquist N; Alenius H; Greco D
Article: PLOS ONE. 2014;9(8):e105238
IL-17/Th17 Pathway Is Activated in Acne Lesions
Kelhala H-L; Palatsi R; Fyhrquist N; Lehtimaki S; Vayrynen JP; Kallioinen M; Kubin ME; Greco D; Tasanen K; Alenius H; Bertino B; Carlavan I; Mehul B; Deret S; Reiniche P; Martel P; Marty C; Blume-Peytavi U; Voegel JJ; Lauerma A
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2013;133(4):964-972
Toll-Like Receptor Activation during Cutaneous Allergen Sensitization Blocks Development of Asthma through IFN-Gamma-Dependent Mechanisms
Haapakoski R; Karisola P; Fyhrquist N; Savinko T; Lehtimaki S; Wolff H; Lauerma A; Alenius H
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(12):2744-2751
The Temporal and Spatial Dynamics of Foxp3+Treg Cell-Mediated Suppression during Contact Hypersensitivity Responses in a Murine Model
Lehtimaki S; Savinko T; Lahl K; Sparwasser T; Wolff H; Lauerma A; Alenius H; Fyhrquist N
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(6):1672-1680
Foxp3+ Cells Control Th2 Responses in a Murine Model of Atopic Dermatitis
Fyhrquist N; Lehtimaki S; Lahl K; Savinko T; Lappetelainen A-M; Sparwasser T; Wolff H; Lauerma A; Alenius H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(21):8334-8339
Environmental biodiversity, human microbiota, and allergy are interrelated
Hanski I; von Hertzen L; Fyhrquist N; Koskinen K; Torppa K; Laatikainen T; Karisola P; Auvinen P; Paulin L; Makela MJ; Vartiainen E; Kosunen TU; Alenius H; Haahtela T
Article: PLOS ONE. 2012;7(8):e41038
CD8+T Cell Migration to the Skin Requires CD4+Help in a Murine Model of Contact Hypersensitivity
Fyhrquist N; Wolff H; Lauerma A; Alenius H
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2011;44(5):639-647
Intradermal Cytosine-Phosphate-Guanosine Treatment Reduces Lung Inflammation but Induces IFN-γ-Mediated Airway Hyperreactivity in a Murine Model of Natural Rubber Latex Allergy
Haapakoski R; Karisola P; Fyhrquist N; Savinko T; Wolff H; Turjanmaa K; Palosuo T; Reunala T; Lauerma A; Alenius H
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130(12):2743-2751
Absence of CCR4 Exacerbates Skin Inflammation in an Oxazolone-Induced Contact Hypersensitivity Model
Lehtimaki S; Tillander S; Puustinen A; Matikainen S; Nyman T; Fyhrquist N; Savinko T; Majuri M-L; Wolff H; Alenius H; Lauerma A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;126(3):581-9.e1-20-U306
MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Stahle M; Pivarcsi A
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2010;151(2):155-167
Smad3 Regulates Dermal Cytokine and Chemokine Expression and Specific Antibody Production in Murine Responses to a Respiratory Chemical Sensitizer
Anthoni M; Fyhrquist N; Lehtimaki S; Alenius H; Wolff H; Lauerma A
Article: BRITISH JOURNAL OF DERMATOLOGY. 2008;159(3):546-554
Transforming growth factor-β/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity
Anthoni M; Fyhrquist-Vanni N; Wolff H; Alenius H; Lauerma A
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2008;147(1):41-51
Immunostimulatory sequence CpG elicits Th1-type immune responses in inflammatory skin lesions in an atopic dermatitis murine model
Wang G; Fyhrquist-Vanni N; Wolff H; Dieu-Nosjean M-C; Kemeny L; Homey B; Lauerma AI; Alenius H
Article: DERMATOLOGIC CLINICS. 2007;25(4):613-x
Contact dermatitis
Fyhrquist-Vanni N; Alenius H; Lauerma A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2006;173(5):512-518
Intranasal exposure to Stachybotrys chartarum enhances airway inflammation in allergic mice
Leino MS; Alenius HT; Fyhrquist-Vanni N; Wolff HJ; Reijula KE; Hintikka EL; Salkinoja-Salonen MS; Haahtela T; Mäkelä MJ
Article: JOURNAL OF IMMUNOLOGY. 2005;175(12):8320-8326
Topical superantigen exposure induces epidermal accumulation of CD8⁺ T cells, a mixed Th1/Th2-type dermatitis and vigorous production of IgE antibodies in the murine model of atopic dermatitis
Savinko T; Lauerma A; Lehtimäki S; Gombert M; Majuri ML; Fyhrquist-Vanni N; Dieu-Nosjean MC; Kemeny L; Wolff H; Homey B; Alenius H
Article: JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY. 2005;191(9):837-844
The photoactivation energy of the visual pigment in two spectrally different populations of Mysis relicta (Crustacea, Mysida)
Pahlberg J; Lindström M; Ala-Laurila P; Fyhrquist-Vanni N; Koskelainen A; Donner K
Article: JOURNAL OF EXPERIMENTAL BIOLOGY. 2003;206(15):2611-2617
Polymorphism of the rod visual pigment between allopatric populations of the sand goby (Pomatoschistus minutus):: a microspectrophotometric study
Jokela M; Vartio A; Paulin L; Fyhrquist-Vanni N; Donner K
Article: VISUAL NEUROSCIENCE. 2000;17(4):509-528
In search of the visual pigment template
Govardovskii VI; Fyhrquist N; Reuter T; Kuzmin DG; Donner K
Article: NATURE. 2000;403(6766):220-223
Measurement of thermal contribution to photoreceptor sensitivity
Koskelainen A; Ala-Laurila P; Fyhrquist N; Donner K
Article: EXPERIMENTAL EYE RESEARCH. 1998;66(3):295-305
Rhodopsins from three frog and toad species: Sequences and functional comparisons
Fyhrquist N; Donner K; Hargrave PA; McDowell JH; Popp MP; Smith WC
Article: VISION RESEARCH. 1998;38(4):483-486
Rod pigment and rod noise in the European toad Bufo bufo
Fyhrquist N; Govardovskii V; Leibrock C; Reuter T
Journal article: PERCEPTION. 1997;26(1_suppl):149
Rhodopsins with Similar Absorbance Characteristics but Different Rates of Thermal Activation: Amino Acid Sequences
Fyhrquist N; Donner K; Hargrave PA; McDowell JH; Popp MP; Smith WC
Article: VISION RESEARCH. 1996;36(20):3253-3264
The effect of background luminance on visual responses to strong flashes: Perceived brightness and the early rise of photoreceptor responses
Djupsund K; Fyhrquist N; Hariyama T; Donner K
Visa fler

Alla övriga publikationer

Preprint: MEDRXIV. 2025
Lifestyle associates with unique resistome and microbiome signatures in children
Duehr H; Paernaenen K; Kucharikova N; Werner P; Pershagen G; Lahti L; Alenius H; Bergstroem A; Ruuskanen M; Fyhrquist N
Book chapter: THE SKIN MICROBIOME MANUAL. 2025;p. 155-161
Skin Microbiome in Psoriasis
Fyhrquist N; Lauerma A
Book chapter: THE SKIN MICROBIOME MANUAL. 2025;p. 173-182
The Skin Microbiome: Potential for Novel Diagnostic and Therapeutic Strategies
Salava A; Fyhrquist N
Preprint: BIORXIV. 2023
MeXpose - A modular imaging pipeline for the quantitative assessment of cellular metal bioaccumulation
Braun G; Schaier M; Werner P; Theiner S; Zanghellini J; Wisgrill L; Fyhrquist N; Koellensperger G
Preprint: RESEARCH SQUARE. 2023
Integrative network analysis suggests prioritised drugs for atopic dermatitis
Federico A; Möbus L; Al-Abdulraheem Z; Pavel A; Fortino V; Giudice GD; Alenius H; Fyhrquist N; Greco D
Review: ALLERGY. 2023;78(5):1169-1203
Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis
Bousquet J; Melen E; Haahtela T; Koppelman GH; Togias A; Valenta R; Akdis CA; Czarlewski W; Rothenberg M; Valiulis A; Wickman M; Akdis M; Aguilar D; Bedbrook A; Bindslev-Jensen C; Bosnic-Anticevich S; Boulet LP; Brightling CE; Brussino L; Burte E; Bustamante M; Canonica GW; Cecchi L; Celedon JC; Chaves Loureiro C; Costa E; Cruz AA; Erhola M; Gemicioglu B; Fokkens WJ; Garcia-Aymerich J; Guerra S; Heinrich J; Ivancevich JC; Keil T; Klimek L; Kuna P; Kupczyk M; Kvedariene V; Larenas-Linnemann DE; Lemonnier N; Carlsen KCL; Louis R; Makela M; Makris M; Maurer M; Momas I; Morais-Almeida M; Mullol J; Naclerio RN; Nadeau K; Nadif R; Niedoszytko M; Okamoto Y; Ollert M; Papadopoulos NG; Passalacqua G; Patella V; Pawankar R; Pham-Thi N; Pfaar O; Regateiro FS; Ring J; Rouadi PW; Samolinski B; Sastre J; Savoure M; Scichilone N; Shamji MH; Sheikh A; Siroux V; Sousa-Pinto B; Standl M; Sunyer J; Taborda-Barata L; Toppila-Salmi S; Torres MJ; Tsiligianni I; Valovirta E; Vandenplas O; Ventura MT; Weiss S; Yorgancioglu A; Zhang L; Latiff AHA; Aberer W; Agache I; Al-Ahmad M; Alobid I; Ansotegui IJ; Arshad SH; Asayag E; Barbara C; Baharudin A; Battur L; Bennoor KS; Berghea EC; Bergmann KC; Bernstein D; Bewick M; Blain H; Bonini M; Braido F; Buhl R; Bumbacea RS; Bush A; Calderon M; Calvo-Gil M; Camargos P; Caraballo L; Cardona V; Carr W; Carreiro-Martins P; Casale T; Cepeda Sarabia AM; Chandrasekharan R; Charpin D; Chen YZ; Cherrez-Ojeda I; Chivato T; Chkhartishvili E; Christoff G; Chu DK; Cingi C; Correia de Sousa J; Corrigan C; Custovic A; D'Amato G; Del Giacco S; De Blay F; Devillier P; Didier A; do Ceu Teixeira M; Dokic D; Douagui H; Doulaptsi M; Durham S; Dykewicz M; Eiwegger T; El-Sayed ZA; Emuzyte R; Fiocchi A; Fyhrquist N; Gomez RM; Gotua M; Guzman MA; Hagemann J; Hamamah S; Halken S; Halpin DMG; Hofmann M; Hossny E; Hrubisko M; Irani C; Ispayeva Z; Jares E; Jartti T; Jassem E; Julge K; Just J; Jutel M; Kaidashev I; Kalayci O; Kalyoncu AF; Kardas P; Kirenga B; Kraxner H; Kull I; Kulus M; La Grutta S; Lau S; Thi LLT; Levin M; Lipworth B; Lourenco O; Mahboub B; Martinez-Infante E; Matricardi P; Miculinic N; Migueres N; Mihaltan F; Mohammad Y; Moniuszko M; Montefort S; Neffen H; Nekam K; Nunes E; Tshipukane DN; O'Hehir R; Ogulur I; Ohta K; Okubo K; Ouedraogo S; Olze H; Pali-Schoell I; Palomares O; Palosuo K; Panaitescu C; Panzner P; Park HS; Pitsios C; Plavec D; Popov TA; Puggioni F; Quirce S; Recto M; Repka-Ramirez MS; Robalo Cordeiro C; Roche N; Rodriguez-Gonzalez M; Romantowski J; Rosario Filho N; Rottem M; Sagara H; Serpa FS; Sayah Z; Scheire S; Schmid-Grendelmeier P; Sisul JC; Sole D; Soto-Martinez M; Sova M; Sperl A; Spranger O; Stelmach R; Ulrik CS; Thomas M; To T; Todo-Bom A; Tomazic PV; Urrutia-Pereira M; Valentin-Rostan M; Van Ganse E; van Hage M; Vasankari T; Vichyanond P; Viegi G; Wallace D; Wang DY; Williams S; Worm M; Yiallouros P; Yusuf O; Zaitoun F; Zernotti M; Zidarn M; Zuberbier J; Fonseca JA; Zuberbier T; Anto JM
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(5):S178
Host transcriptomes that define microbiota during cutaneous homeostasis and inflammation
Olah P; Radai Z; Smits JP; Gomez-Casado C; Consortium EM; Sinkko H; Fyhrquist N; Andersson B; Alenius H; Homey B
Conference publication: 2023
Machine-Learning-Driven Biomarker Discovery for the Discrimination between Allergic and Irritant Contact Dermatitis
Fortino V; Wisgrill L; Werner P; Suomela S; Linder N; Lauerma A; Aalto-Korte K; Greco D; Fyhrquist N
Review: FRONTIERS IN ALLERGY. 2023;4:1152927
A short history from Karelia study to biodiversity and public health interventions
Haahtela T; Alenius H; Auvinen P; Fyhrquist N; von Hertzen L; Jousilahti P; Karisola P; Laatikainen T; Lehtimaki J; Paalanen L; Ruokolainen L; Saarinen K; Valovirta E; Vasankari T; Vlasoff T; Erhola M; Bousquet J; Vartiainen E; Makela MJJ
Editorial comment: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(3 PT A):509-512
New Key Players in Irritant Contact Dermatitis: Residential Skin Cells and Neutrophils Drive Inflammation
Lauerma A; Werner P; Wisgrill L; Fyhrquist N
Book chapter: ARTIFICIAL INTELLIGENCE IN MEDICINE. 2022;p. 1411-1423
AIM in Allergy
Wisgrill L; Werner P; Fortino V; Fyhrquist N
Conference publication: ACTA DERMATO-VENEREOLOGICA. 2022;102:16
INTERACTIVITY BETWEEN COMPONENTS OF THE MICROBIOME IN PSORIASIS AND ATOPIC ECZEMA
Fyhrquist N
Review: ALLERGY. 2021;76(12):3613-3626
Immunological resilience and biodiversity for prevention of allergic diseases and asthma
Haahtela T; Alenius H; Lehtimaki J; Sinkkonen A; Fyhrquist N; Hyoty H; Ruokolainen L; Makela MJ
Review: EXPERIMENTAL DERMATOLOGY. 2021;30(10):1517-1531
The power and potential of BIOMAP to elucidate host-microbiome interplay in skin inflammatory diseases
Alenius H; Sinkko H; Moitinho-Silva L; Rodriguez E; Broderick C; Alexander H; Reiger M; Hjelmso MH; Fyhrquist N; Olah P; Bryce P; Smith C; Koning F; Eyerich K; Greco D; van den Bogaard EH; Neumann AU; Traidl-Hoffmann C; Homey B; Flohr C; Bonnelykke K; Stokholm J; Weidinger S
Letter: ALLERGY. 2021;76(4):1280-1284
Interplay between skin microbiota and immunity in atopic individuals
Riskumaki M; Tessas I; Ottman N; Suomalainen A; Werner P; Karisola P; Lauerma A; Ruokolainen L; Karkman A; Wisgrill L; Sinkko H; Lehtimaki J; Alenius H; Fyhrquist N
Letter: ALLERGY. 2021;76(4):1257-1261
Identification of novel miRNA-mRNA regulatory networks in contact dermatitis by integrated microarray analysis
Werner P; Wisgrill L; Riskumaki M; Jalonen E; Vendelin J; Suomela S; Lauerma A; Alenius H; Fyhrquist N
Preprint: AUTHOREA. 2021
Immunological resilience and biodiversity for prevention
Haahtela T; Alenius H; Lehtimäki J; Sinkkonen A; Fyhrquist N; Hyoty H; Ruokolainen L; Makela M
Book chapter: ARTIFICIAL INTELLIGENCE IN MEDICINE. 2021;p. 1-13
AIM in Allergy
Wisgrill L; Werner P; Fortino V; Fyhrquist N
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):1139-1140
The role of soil exposure in asthma prevention during neonatal period Reply
Ottman N; Fyhrquist N
Meeting abstract: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(9):S257
Influence of filaggrin loss-of-function mutations in hostemicrobe interactions during atopic skin inflammation
Olah P; Szlavicz E; Consortium E; Rodriguez E; Weidinger S; Fyhrquist N; Alenius H; Lauerma A; Andersson B; Homey B
Letter: ALLERGY. 2019;74(7):1377-1380
CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response
Karra L; Gangwar RS; Puzzovio PG; Fyhrquist N; Minai-Fleminger Y; Landolina N; Simon H-U; Alenius H; Leibovici V; Simon D; Levi-Schaffer F
Letter: ALLERGY. 2019;74(3):617-621
Tape-stripping alters the microbe-host correlations in mouse skin
Karisola P; Suomalainen A; Fortino V; Ottman N; Vendelin J; Wolff HJ; Ruokolainen L; Greco D; Fyhrquist N; Alenius H
Review: CLINICAL AND TRANSLATIONAL ALLERGY. 2019;9:3
The roadmap for the Allergology specialty and allergy care in Europe and adjacent countries. An EAACI position paper
Fyhrquist N; Werfel T; Bilo MB; Muelleneisen N; van Wijk RG
Conference publication: ALLERGY. 2018;73:834
Key genes distinguishing irritant and allergic contact dermatitis from other types of dermatitis
Fortino V; Suomela S; Suomalainen A; Marwah V; Lehto E; Vendelin J; Lauerma A; Pesonen M; Aalto-Korte K; Greco D; Alenius H; Fyhrquist N
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(2):ab238
CD300a: A New Player in Atopic Dermatitis?
Karra L; Gangwar RS; Levi T; Minai-Fleminger Y; Fyhrquist N; Leibovic V; Simon D; Levi-Schaffer F
Conference publication: ALLERGY. 2017;72:497
The living environment shapes intestinal microbial communities and immune responses in a mouse model
Ottman N; Ruokolainen L; Suomalainen A; Karisola P; Lehtimaki J; Lehto M; Hanski I; Alenius H; Fyhrquist N
Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2016;16(5):421-426
The rich and the poor: environmental biodiversity protecting from allergy
Ruokolainen L; Fyhrquist N; Haahtela T
Meeting abstract: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(9):s232
Isotretinoin and lymecycline treatments modify the skin microbiota in acne
Kelhala H; Aho V; Fyhrquist N; Pereira P; Kubin M; Paulin L; Palatsi R; Auvinen P; Tasanen K; Lauerma A
Review: CURRENT ALLERGY AND ASTHMA REPORTS. 2016;16(5):40
Skin Biomes
Fyhrquist N; Salava A; Auvinen P; Lauerma A
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2016;83(5):380-381
Microbe-host interplay in atopic dermatitis and psoriasis
Fyhrquist N; Andersson B; Kere J; Muirhead G; Prast-Nielsen S; Jeanmougin M; Barker J; Lauerma A; Homey B; Schroeder J; Soumelis V; Nestle F; Alenius H
Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2014;14(5):430-435
New findings in allergic contact dermatitis
Fyhrquist N; Lehto E; Lauerma A
Conference publication: ALLERGY. 2012;67:139-140
The temporal and spatial dynamics of Treg cell-mediated suppression during contact hypersensitivity responses in a murine model
Fyhrquist N; Lehtimaki S; Savinko T; Lahl K; Sparwasser T; Wolff H; Lauerma A; Alenius H
Editorial comment: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130(2):342-344
MK2 Signaling: Lessons on Tissue Specificity in Modulation of Inflammation
Fyhrquist N; Matikainen S; Lauerma A
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130:S3
MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4
Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Stahle M; Pivarcsi A
Conference publication: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130:S34
CD8+T cell migration to hapten exposed skin sites requires CD4+help in a murine model
Fyhrquist N; Wolff H; Lauerma A; Alenius H
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(1):s3
Cutaneous CpG administration reduces Th2-type airway inflammation but induces airway hyperreactivity
Haapakoski R; Fyhrquist-Vanni N; Savinko T; Wolff H; Turjanmaa K; Palosuo T; Reunala T; Lauerma A; Alenius H
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(1):S284
The role of STAT6 in the murine model of atopic dermatitis
Alenius H; Savinko T; Lehtimaki S; Fyhrquist-Vanni N; Wolff H; Lauerma A
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):s245
The role of T cells in a murine model of contact hypersensitivity
Fyhrquist-Vanni N; Lauerma A; Alenius H
Conference publication: PERCEPTION. 1997;26:14-15
Rhodopsins with similar absorbance characteristics but different rates of thermal activation: amino acid sequences
Fyhrquist N; Donner K; Hargrave PA; McDowell JH; Popp MP; Smith WC
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Forskningsbidrag

Interaction between living environment, human microbiome and immune system related to allergy
Swedish Research Council
1 January 2021 - 31 December 2024
Toward improved diagnostics of allergic and irritant contact dermatitis
Swedish Research Council for Health Working Life and Welfare
1 January 2019 - 31 December 2021
Impact of the living environment and the human microbiota on immune homeostasis and immune dysregulation leading to allergy: Karelia Allergy Study
Swedish Research Council
1 January 2018 - 31 December 2020
Regulatory mechanisms in a murine model of T-cell mediated skin
Academy of Finland
8 January 2005 - 31 December 2008
Regulatory mechanisms in a murine model of T-cell mediated skin
Academy of Finland
8 January 2005 - 31 December 2008

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