Milan Chromek

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Utvalda publikationer

Article: SCIENTIFIC REPORTS. 2025;15(1):2645
Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease
Lindblad YT; Tothova L; Celec P; Kublickiene K; Barany P; Chromek M
Article: PEDIATRIC NEPHROLOGY. 2023;38(4):1205-1214
Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy
Grossmann KR; Vishnevskaya L; Ruiz SD; Kublickiene K; Barany P; Blennow M; Chromek M
Article: ACTA PAEDIATRICA. 2022;111(1):86-92
Acute kidney injury in infants with hypothermia-treated hypoxic-ischaemic encephalopathy: An observational population-based study
Grossmann KR; Barany P; Blennow M; Chromek M
Article: ARCHIVES OF DISEASE IN CHILDHOOD. 2021;106(5):491-495
Hyponatraemia despite isotonic maintenance fluid therapy: a time series intervention study
Chromek M; Jungner A; Rudolfson N; Ley D; Bockenhauer D; Hagander L
Article: ACTA PAEDIATRICA. 2019;108(3):551-556
Association between vitamin D, antimicrobial peptides and urinary tract infection in infants and young children
Georgieva V; Kamolvit W; Herthelius M; Luethje P; Brauner A; Chromek M
Article: PLOS ONE. 2012;7(10):e46476
The Antimicrobial Peptide Cathelicidin Protects Mice from Escherichia coli O157:H7-Mediated Disease
Chromek M; Arvidsson I; Karpman D
Article: NATURE MEDICINE. 2006;12(6):636-641
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection
Chromek M; Slamova Z; Bergman P; Kovacs L; Podracka L; Ehren I; Hokfelt T; Gudmundsson GH; Gallo RL; Agerberth B; Brauner A

Artiklar

Journal article: KIDNEY INTERNATIONAL. 2025;107(1):116-129
Presentation and outcome in carriers of pathogenic variants in SLC34A1 and SLC34A3 encoding sodium-phosphate transporter NPT 2a and 2c
Brunkhorst M; Brunkhorst L; Martens H; Papizh S; Besouw M; Grasemann C; Turan S; Sikora P; Chromek M; Cornelissen E; Fila M; Lilien M; Allgrove J; Neuhaus TJ; Eltan M; Espinosa L; Schnabel D; Gokce I; Gonzalez-Rodriguez JD; Khandelwal P; Keijzer-Veen MG; Lechner F; Szcepanska M; Zaniew M; Bacchetta J; Emma F; Haffner D
Article: MICROORGANISMS. 2024;12(3):589
Prevalence and Characteristics of Plasmid-Encoded Serine Protease EspP in Clinical Shiga Toxin-Producing Escherichia coli Strains from Patients in Sweden
Wang L; Hua Y; Bai X; Zhang J; Mernelius S; Chromek M; Frykman A; Hansson S; Matussek A
Article: CELLS. 2023;12(24):2774
Levels of Cell-Free DNA in Kidney Failure Patients before and after Renal Transplantation
Leotta C; Hernandez L; Tothova L; Arefin S; Ciceri P; Cozzolino MG; Barany P; Chromek M; Stenvinkel P; Kublickiene K
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2023;42(6):771-779
Genome-wide association study of hemolytic uremic syndrome causing Shiga toxin-producing Escherichia coli from Sweden, 1994-2018
Matussek A; Mernelius S; Chromek M; Zhang J; Frykman A; Hansson S; Georgieva V; Xiong Y; Bai X
Article: PEDIATRIC NEPHROLOGY. 2022;37(12):3165-3175
Cardiac biomarkers in pediatric CKD-a prospective follow-up study
Lindblad YT; Vavilis G; Chromek M; Quershi AR; Lowbeer C; Barany P
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11S):964
Role of Cell-Free DNA in the Follow-Up of CKD Patients After Kidney Transplantation
Leotta C; Hernandez LN; Tothova L; Chromek M; Ciceri P; Cozzolino M; Stenvinkel P; Kublickiene K
Article: VIRULENCE. 2021;12(1):1296-1305
Whole-genome characterization of hemolytic uremic syndrome-causing Shiga toxin-producing Escherichia coli in Sweden
Hua Y; Chromek M; Frykman A; Jernberg C; Georgieva V; Hansson S; Zhang J; Marits AK; Wan C; Matussek A; Bai X
Article: TOXINS. 2021;13(1):71
Molecular Characterization of the Enterohemolysin Gene (ehxA) in Clinical Shiga Toxin-Producing Escherichia coli Isolates
Hua Y; Zhang J; Jernberg C; Chromek M; Hansson S; Frykman A; Xiong Y; Wan C; Matussek A; Bai X
Article: EMERGING MICROBES & INFECTIONS. 2020;9(1):2562-2570
Molecular characteristics of eae-positive clinical Shiga toxin-producing Escherichia coli in Sweden
Hua Y; Bai X; Zhang J; Jernberg C; Chromek M; Hansson S; Frykman A; Yang X; Xiong Y; Wan C; Matussek A
Article: SCIENTIFIC REPORTS. 2019;9(1):14362
Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism
Johansson KE; Stahl A-L; Arvidsson I; Loos S; Tontanahal A; Rebetz J; Chromek M; Kristoffersson A-C; Johannes L; Karpman D
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34(6):981-991
Treatment and long-term outcome in primary distal renal tubular acidosis
Lopez-Garcia SC; Emma F; Walsh SB; Fila M; Hooman N; Zaniew M; Bertholet-Thomas A; Colussi G; Burgmaier K; Levtchenko E; Sharma J; Singhal J; Soliman NA; Ariceta G; Basu B; Murer L; Tasic V; Tsygin A; Decramer S; Gil-Pena H; Koster-Kamphuis L; La Scola C; Gellermann J; Konrad M; Lilien M; Francisco T; Tramma D; Trnka P; Yuksel S; Caruso MR; Chromek M; Ekinci Z; Gambaro G; Kari JA; Koenig J; Taroni F; Thumfart J; Trepiccione F; Winding L; Wuehl E; Agbas A; Belkevich A; Vargas-Poussou R; Blanchard A; Conti G; Boyer O; Dursun I; Pinarbasi AS; Melek E; Miglinas M; Novo R; Mallett A; Milosevic D; Szczepanska M; Wente S; Cheong HI; Sinha R; Gucev Z; Dufek S; Iancu D; Kleta R; Schaefer F; Bockenhauer D; Peco-Antic A; Kaur A; Paglialunga A; Servais A; Lutovac B; Hoorn EJ; Shasha-Lavsky H; Harambat J; Godron-Dubrasquet A; Buder K; Allard L; Patzer L; Shumikhina M; Hansen M; Printza N; Kucuk N; Beringer O; Bhimma R; Cerkauskiene R; Klinikos S; Neuhaus TJ; Stavileci V; Ulinski T; Dincel NT; Mohebbi N
Article: MBIO. 2018;9(4):e01462-e01418
Discovery of New Genes Involved in Curli Production by a Uropathogenic Escherichia coli Strain from the Highly Virulent O45:K1:H7 Lineage
Nguyen TKN; Minh-Duy P; Peters KM; Lo AW; Forde BM; Chong TM; Yin W-F; Chan K-G; Chromek M; Brauner A; Chapman MR; Beatson SA; Schembri MA
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2018;96(6):537-545
Psoriasin, a novel anti-Candida albicans adhesin
Brauner A; Alvendal C; Chromek M; Stopsack KH; Ehrstrom S; Schroeder JM; Bohm-Starke N
Article: JOURNAL OF IMMUNOLOGY. 2016;197(4):1276-1286
Early Terminal Complement Blockade and C6 Deficiency Are Protective in Enterohemorrhagic Escherichia coli-Infected Mice
Arvidsson I; Rebetz J; Loos S; Herthelius M; Kristoffersson A-C; Englund E; Chromek M; Karpman D
Journal article: LAKARTIDNINGEN. 2015;112:DI7D
[The council for new therapies should immediately revoke their decision on eculizumab].
Karpman D; Fehrman-Ekholm I; Bárány P; Békássy Z; Brandström P; Bruchfeld A; Celsi G; Chromek M; Clyne N; Fellström B; Hansson S; Haraldsson B; Nevéus T; Rippe B; Sartz L; Segelmark M; Stegmayr B; Stenvinkel P; Westman K
Journal article: LAKARTIDNINGEN. 2015;112:DI3F
[The council for new therapies position on eculizumab is unacceptable].
Karpman D; Fehrman-Ekholm I; Bárány P; Békássy Z; Brandström P; Bruchfeld A; Celsi G; Chromek M; Clyne N; Fellström B; Hansson S; Haraldsson B; Nevéus T; Rippe B; Sartz L; Segelmark M; Stegmayr B; Stenvinkel P; Tufveson G; Westman K
Article: PLOS PATHOGENS. 2015;11(2):e1004619
A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles
Stahl A-L; Arvidsson I; Johansson KE; Chromek M; Rebetz J; Loos S; Kristoffersson A-C; Bekassy ZD; Morgelin M; Karpman D
Article: PEDIATRIC NEPHROLOGY. 2013;28(10):2003-2013
Left ventricular diastolic dysfunction by tissue Doppler echocardiography in pediatric chronic kidney disease
Lindblad YT; Axelsson J; Balzano R; Vavilis G; Chromek M; Celsi G; Barany P
Article: PLOS ONE. 2010;5(12):e15580
Vitamin D Induction of the Human Antimicrobial Peptide Cathelicidin in the Urinary Bladder
Hertting O; Holm A; Luthje P; Brauner H; Dyrdak R; Jonasson AF; Wiklund P; Chromek M; Brauner A
Article: PLOS PATHOGENS. 2010;6(7):e1001010
Uropathogenic Escherichia coli Modulates Immune Responses and Its Curli Fimbriae Interact with the Antimicrobial Peptide LL-37
Kai-Larsen Y; Luthje P; Chromek M; Peters V; Wang X; Holm A; Kadas L; Hedlund K-O; Johansson J; Chapman MR; Jacobson SH; Romling U; Agerberth B; Brauner A
Article: ENVIRONMENTAL MICROBIOLOGY. 2009;11(5):1105-1116
Characterization of cellulose production in Escherichia coli Nissle 1917 and its biological consequences
Monteiro C; Saxena I; Wang X; Kader A; Bokranz W; Simm R; Nobles D; Chromek M; Brauner A; Brown RMJ; Romling U
Article: TOXICON. 2008;51(8):1544-1547
Cytotoxic necrotizing factor 1 (CNF1) induces an inflammatory response in the urinary tract in vitro but not in vivo
Hertting O; Chromek M; Slamova Z; Kadas L; Soderkvist M; Vainumae I; Tallvik T; Jacobson SH; Brauner A
Journal article: CURRENT PEDIATRIC REVIEWS. 2007;3(1):35-44
Urinary Tract Infection. Why Do Some Children Get Complications, While Others Don't?
Chromek M; Brauner A
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2006;17(12):3270-3272
What keeps the urinary tract sterile?: The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.: Nat Med 12: 636-640, 2006
Chromek M; Slamova Z; Bergman P; Kovacs L; Podracka L; Ehren I; Hoekfelt T; Gudmundsson G; Gallo R; Agerberth B; Brauner
Article: REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY. 2005;3:39
Non-infected preterm parturition is related to increased concentrations of IL-6, IL-8 and MCP-1 in human cervix -: art. no. 39
Törnblom SA; Klimaviciute A; Byström B; Chromek M; Brauner A; Ekman-Ordeberg G
Article: NEUROCHEMISTRY INTERNATIONAL. 2005;46(7):551-557
Soluble interleukin-1 receptor type II, IL-18 and caspase-1 in mild cognitive impairment and severe Alzheimer's disease
Lindberg C; Chromek M; Ahrengart L; Brauner A; Schultzberg M; Garlind A
Article: JOURNAL OF UROLOGY. 2005;173(4):1381-1384
Interleukin-8 response in cells from the human urinary tract induced by lipopolysaccharides of proteus mirabilis O3 and O18
Chromek M; Stankowska D; Dadfar E; Kaca W; Rabbani H; Brauner A
Article: INFECTION AND IMMUNITY. 2004;72(1):82-88
Tissue inhibitor of metalloproteinase 1 activates normal human granulocytes, protects them from apoptosis, and blocks their transmigration during inflammation
Chromek M; Tullus K; Lundahl J; Brauner A
Article: PEDIATRIC RESEARCH. 2003;53(4):698-705
Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinases-1 in acute pyelonephritis and renal scarring
Chromek M; Tullus K; Hertting O; Jaremko G; Khalil A; Li YH; Brauner A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;131(2):225-233
Enhanced chemokine response in experimental acute Escherichia coli pyelonephritis in IL-1β-deficient mice
Hertting O; Khalil A; Jaremko G; Chromek M; Li YH; Bakhiet M; Bartfai T; Tullus K; Brauner A
Article: PERITONEAL DIALYSIS INTERNATIONAL. 2003;23(1):5-13
CAPD peritonitis induces the production of a novel peptide, daintain/allograft inflammatory factor-1
Brauner A; Hertting O; Alkstrand E; Sandberg E; Chromek M; Chen ZW; Östenson CG
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Alla övriga publikationer

Conference publication: PEDIATRIC NEPHROLOGY. 2024;39(1):S63
Extracellular DNA in children with chronic kidney disease
Lindblad YT; Tothova L; Celec P; Kublickiene K; Barany P; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2024;39(1):S41-S42
Atypical picture of micturating cystography in the boy with posterior urethra valve
Niwinska-Faryna B; Herthelius M; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2024;39(1):S392-S393
New onset IgA vasculitis in a kidney transplant recipient-a case report
Niwinska-Faryna B; Herthelius M; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2023;38:S244
TWO CASES OF ISOLATED PROXIMAL RENAL TUBULAR ACIDOSIS CAUSED BY SLC4A4 MUTATIONS
Csomo D; Chromek M; Podracka L
Conference publication: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2022;33(11):964
Role of Cell-Free DNA in the Follow-Up of CKD Patients After Kidney Transplantation
Leotta C; Hernandez LN; Tothova L; Chromek M; Ciceri P; Cozzolino M; Stenvinkel P; Kublickiene K
Conference publication: PEDIATRIC NEPHROLOGY. 2022;37(11):2851-2852
RENAL FUNCTION IN SURVIVORS OF HYPOTHERMIA-TREATED HYPOXIC-ISCHAEMIC ENCEPHALOPATHY AFTER 10-12 YEARS
Grossmann KR; Vishnevskaya L; Blennow M; Barany P; Chromek M
Editorial comment: ACTA PAEDIATRICA. 2021;110(4):1289-1290
Paediatricians face challenging times as COVID-19 can cloud other diagnoses and lead to treatment delays
Marits AK; Fischler B; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2021;36(10):3324
ACUTE KIDNEY INJURY AFTER ALLOGENEIC HAEMATOPOIETIC CELL TRANSPLANTATION IN CHILDREN - A SINGLE CENTRE OBSERVATIONAL STUDY
Larsson E; Sundin M; Barany P; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2018;33(10):1890-1891
ANTIMICROBIAL ACTIVITY OF PERITONEAL FLUID IN CHILDREN ON PERITONEAL DIALYSIS
Georgieva V; Kamolvit W; Luthje P; Shroff R; Brauner A; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2018;33(10):1836
AKI IN INFANTS WITH HYPOTHERMIA-TREATED HYPOXIC-ISCHAEMIC ENCEPHALOPATHY
Grossmann KR; Chromek M; Barany P; Blennow M
Conference publication: PEDIATRIC NEPHROLOGY. 2018;33(10):1817
LONG-TERM OUTCOME AND TREATMENT PRACTICES IN DISTAL RENALTUBULAR ACIDOSIS
Garcia SCL; Emma F; Walsh S; Fila M; Hooman N; Marcin Z; Bertholet-thomas A; Colussi G; Ebner K; Levtchenko E; Sharma J; Singhal J; Soliman NA; Ariceta C; Basu B; Murer L; Tasic V; Tsygin A; Demmer S; Gil-pena H; Koster-Kamphuis L; La Scola C; Gellermann J; Konrad M; Lilien M; Francisco T; Tramma D; Tmka P; Yuksel S; Caruso MR; Chromek M; Ekinci Z; Gambaro G; Kari J; Konig J; Taroni F; Thumfart J; Trepiccione F; Winding L; Wuhl E; Agbas A; Belkevich A; Vargas-poussou R; Blanchard A; Conti G; Boyer O; Dursun I; Coskun AS; Melek E; Miglinas M; Novo R; Mallen A; Milosevic D; Szczepanska M; Wente S; Consortium D; Kleta R; Schaefer F; Bockenhauer D
Conference publication: PEDIATRIC NEPHROLOGY. 2017;32(9):1708
THE ASSOCIATION BETWEEN VITAMIN D STATUS, ANTIMICROBIAL PEPTIDES AND URINARY TRACT INFECTION IN SMALL CHILDREN
Georgieva V; Kamolvit W; Herthelius M; LUthje P; Brauner A; Chromek M
Review: PEDIATRIC NEPHROLOGY. 2015;30(8):1225-1232
The role of the antimicrobial peptide cathelicidin in renal diseases
Chromek M
Conference publication: MOLECULAR IMMUNOLOGY. 2015;67(1):120
Early treatment with terminal complement blockade and C6 deficiency protect mice from enterohemorrhagic Escherichia coli infection
Arvidsson I; Rebetz J; Chromek M; Herthelius M; Loos S; Kristoffersson A-C; Karpman D
Conference publication: PEDIATRIC NEPHROLOGY. 2015;30(9):1615
ONE PILL CAN KILL - A CASE REPORT OF A PATIENT WHO SURVIVED A POTENTIALLY LETHAL DOSE OF PMMA
grossmann KR; Fischler B; Krmar R; Herthelius M; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2014;29(9):1796
Vitamin D Deficiency Is Not A Risk Factor Of Recurrent Urinary Tract Infection In Small Children
Georgieva V; Herthelius M; LUthje P; Brauner A; Chromek M
Conference publication: PEDIATRIC NEPHROLOGY. 2012;27(9):1724
EARLY DETECTION OF LEFT VENTRICULAR DYSFUNCTION BY TISSUE DOPPLER ECHOCARDIOGRAPHY IN CHILDREN WITH CHRONIC KIDNEY DISEASE
Lindblad YT; Axelsson J; Balzano R; Vavilis G; Celsi G; Chromek M; Barany P
Conference publication: PEDIATRIC NEPHROLOGY. 2010;25(9):1849
The Antimicrobial Peptide Cathelicidin Interferes with Polymerization of Curli fimbrie and Thus Inhibits the Formation of Uropathogenic E-coli Biofilm
Chromek M; Kai-Larsen Y; Luthje P; Wang X; Holm AA; Hedlund K-O; Johansson J; Chapman MR; Jacobson SH; Romling U; Agerberth B; Brauner A
Review: JOURNAL OF MOLECULAR MEDICINE-JMM. 2008;86(1):37-47
Antimicrobial mechanisms of the urinary tract
Chromek M; Brauner A
Conference publication: PEDIATRIC NEPHROLOGY. 2008;23(9):1698
Uropathogenic E. coli produce biofilms to evade innate immune responses
Chromek M; Wang X; Luthje P; Kadas L; Jacobson SH; Agerberth B; Roemling U; Brauner A
Conference publication: PEDIATRIC NEPHROLOGY. 2007;22(9):1450
Antimicrobial mechanisms of the urinary tract -: the role of cathelicidin
Chromek M; Slamova Z; Bergman P; Kovacs L; Podracka L; Ehren I; Gallo R; Gundmundsson G; Agerberth B; Brauner A
Editorial comment: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2006;17(12):3270-3272
What Keeps the Urinary Tract Sterile?: The Antimicrobial Peptide Cathelicidin Protects the Urinary Tract against Invasive Bacterial Infection. Nat Med 12: 636-640, 2006.
Chromek M; Slamova Z; Bergman P; Kovacs L; Podracka L; Ehren I; Hokfelt T; Gudmundsson G; Gallo R; Agerberth B; Brauner A
Doctoral thesis: 2006
Urinary tract infection and renal scarring
Chromek M
Meeting abstract: PEDIATRIC RESEARCH. 2004;56(3):472
The human cathelicidin:: Another antimicrobial peptide of urinary tract
Chromek M; Agerberth B; Ehrén I; Gudmundsson GH; Fehervízyová Z; Kovács L; Podracka L; Brauner A
Letter: PEDIATRIC RESEARCH. 2004;55(2):357-358
Untitled - Response
Chromek M; Brauner A
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Forskningsbidrag

Antimicrobial peptide cathelicidin in gastrointestinal infection with Enterohemorrhagic Escherichia coli
Swedish Research Council
1 January 2010 - 31 December 2010

Anställningar

Anknuten till Forskning, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2025-2028
Anknuten till Forskning, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023-2025

Examina och utbildning

Docent, pediatrik, Karolinska Institutet, 2022
MEDICINE DOKTORSEXAMEN, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2006

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