Marie Evans

Marie Evans

Anknuten till Forskning | Docent
E-postadress: marie.evans@ki.se
Besöksadress: Baxter Novum, Hälsovägen 7, plan 5, 14186 Stockholm
Postadress: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Med njursjukdomar, 141 52 Huddinge
Del av:

Om mig

  • Research group leader Clinical renal epidemiology, Renal unit, Department of
    Clinical Intervention and Technology
    Consultant nephrology, Karolinska University hospital, ME Renal medicine,
    Attending physician at Rosenlunds dialysis department
    Member of the Swedish Renal Registry steering committee, Medical director of
    the CKD registry (SRR-CKD)
    Member of Region Stockholm’s drug expert committee of chronic kidney
    disease
    Chair of the national network in clinical nephrology research
    Elected member of the ERA-EDTA Registry committee
    Invited member of the FDA/EMA/NKF Workshop on GFR and ACR as endpoints for
    clinical trials in CKD, Silver Spring, MD 2018
    2016-2017 Post-doc United Kingdom Renal Registry, affiliated with Bristol
    University, Bristol, United Kingdom
    2013 Specialist Internal Medicine
    2011 Specialist Nephrology
    2010 PhD Karolinska Institutet (Renal epidemiology) Title: Prognosis and
    progression in chronic kidney disease – decline in estimated renal function
    and mortality
    2003-2004 Research school in clinical epidemiology, Karolinska Institutet
    2001 Licence to practice (certified by the Swedish National Board of health
    and welfare)
    1998, MD Karolinska Institutet

Forskningsbeskrivning

  • The main purpose of my research projects is to better characterize the
    prognosis of chronic kidney disease and its various stages, with a focus on
    cardiovascular mortality and morbidity. We further aim to find risk factors
    and biomarkers of CKD, CKD progression and CKD-related cardiovascular
    disease. We also aim to describe changes in uremic symptoms and quality of
    life in people who experience CKD progression and kidney replacement therapy
    initiation and to explore their associations with different types of
    treatments.
    We use different sources to study our research questions, such as general
    population registries, renal registries, and clinical cohorts. Among the
    epidemiological projects, I mainly use existing registers linked to other
    health data sources (particularly the Swedish Renal Registry - chronic kidney
    disease [SRR-CKD] and Stockholm Creatinine Measurement project [
    SCREAM
    ]. Currently I am leading an initiative to start the first
    registry-randomized controlled trial (INITIATE) in the Swedish Renal
    Registry.
    My projects also include research in clinical cohorts. I am the national
    coordinator for the EQUAL study in Sweden. EQUAL is a European multicenter
    study where about 1700 patients are recruited in 6 countries. Sweden
    participates with 305 patients and 13 clinics. I have coordinated the Swedish
    part of the study which is now just completed; I am part of both the steering
    group and the publication committee. In the EQUAL study we collected data at
    study visits every 3-6 months for 4 years. In addition to routine clinical
    information, nutritional status and patient questionnaires, we have recorded
    repeated body composition, hand-grip measurements, and biobank samples
    (blood, DNA, plasma, serum, urine). Another clinical cohort is the recently
    started RENAL-QS where we will follow clinical symptoms, quality of life and
    biomarkers in patients with advanced stage CKD before and after dialysis
    initiation, and investigate their relationship with different treatment
    alternatives and dialysis modalities.
    *Research group*
    Joakim Österman, MD
    Ehab Al-Sodany, MD, PhD-student
    Ulrika Hahn-Lundström, MD, PhD-student
    Karin Windahl, Rd, PhD-student
    Helena Rydell, MD, PhD, post-doc

Undervisning

  • Teacher at Karolinska Institutet Medical Program, T4-T6
    Course leader (SK-kurs) Renal medicine 2015-ongoing
    1 week post-graduate course
    Clinical teaching assistant T4, Institution of Medicine 2007-2009

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

  • Anknuten till Forskning, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2022-2025

Examina och utbildning

  • Docent, njursjukdomar, Karolinska Institutet, 2021
  • Medicine Doktorsexamen, Institutionen för klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2010
  • Läkarexamen, Karolinska Institutet, 1998

Handledning

  • Jenny Wrackefeldt, Development and implication of a digital application for PROMs in patients with chronic kidney disease, 2023

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