Maja Jagodic

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Maja Jagodic är professor i neuroinflammation, docent i experimentell medicin och gruppledare för forskning om multipel skleros epigenetik vid institutionen för klinisk neurovetenskap och centrum för molekylär medicin.

Artiklar

Journal article: EBIOMEDICINE. 2024;110:105470
Epigenetic age acceleration as a biomarker of amyotrophic lateral sclerosis severity?
Lewandowski SA; Kular L; Jagodic M
Article: NATURE COMMUNICATIONS. 2024;15(1):6419
A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis
Kakhki MP; Giordano A; Cucuzza CS; Badam TVS; Samudyata S; Lemee MV; Stridh P; Gkogka A; Shchetynsky K; Harroud A; Gyllenberg A; Liu Y; Boddul S; James T; Sorosina M; Filippi M; Esposito F; Wermeling F; Gustafsson M; Casaccia P; Hillert J; Olsson T; Kockum I; Sellgren CM; Golzio C; Kular L; Jagodic M
Article: ACTA NEUROPATHOLOGICA. 2024;147(1):82
Physiological aging and inflammation-induced cellular senescence may contribute to oligodendroglial dysfunction in MS
Windener F; Grewing L; Thomas C; Dorion M-F; Otteken M; Kular L; Jagodic M; Antel J; Albrecht S; Kuhlmann T
Article: NATURE IMMUNOLOGY. 2024;25(3):432-447
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
Linnerbauer M; Loesslein L; Vandrey O; Peter A; Han Y; Tsaktanis T; Wogram E; Needhamsen M; Kular L; Nagel L; Zissler J; Andert M; Meszaros L; Hanspach J; Zuber F; Naumann UJ; Diebold M; Wheeler MA; Beyer T; Nirschl L; Cirac A; Laun FB; Guenther C; Winkler J; Baeuerle T; Jagodic M; Hemmer B; Prinz M; Quintana FJ; Rothhammer V
Article: NATURE COMMUNICATIONS. 2024;15(1):383
The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34
Berglund R; Cheng Y; Piket E; Adzemovic MZ; Zeitelhofer M; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;79:104991
Smoking affects epigenetic ageing of lung bronchoalveolar lavage cells in Multiple Sclerosis
Klose D; Needhamsen M; Ringh MV; Hagemann-Jensen M; Jagodic M; Kular L
Article: LEUKEMIA. 2023;37(9):1830-1841
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells
Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
Article: NEUROLOGY. 2023;101(7):e679-e689
Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis
Maltby V; Xavier A; Ewing E; Campagna M-P; Sampangi S; Scott RJ; Butzkueven H; Jokubaitis V; Kular L; Bos S; Slee M; van der Mei IA; Taylor BV; Ponsonby A-L; Jagodic M; Lea R; Lechner-Scott J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(16):12576
DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes
Xavier A; Maltby VE; Ewing E; Campagna MP; Burnard SM; Tegner JN; Slee M; Butzkueven H; Kockum I; Kular L; Jokubaitis VG; Kilpatrick T; Alfredsson L; Jagodic M; Ponsonby A-L; Taylor BV; Scott RJ; Lea RA; Lechner-Scott J
Article: NATURE. 2023;619(7969):323-331
Locus for severity implicates CNS resilience in progression of multiple sclerosis
Harroud A; Stridh PJ; McCauley JH; Saarela J; van den Bosch AMR; Engelenburg H; Beecham A; Alfredsson L; Alikhani K; Amezcua L; Andlauer TFM; Ban M; Barcellos L; Barizzone N; Berge T; Berthele A; Bittner S; Bos S; Briggs FBS; Caillier S; Calabresi P; Caputo D; Carmona-Burgos D; Cavalla P; Celius E; Cerono G; Chinea A; Chitnis T; Clarelli F; Comabella M; Comi G; Cotsapas C; Cree BCA; D'Alfonso S; Dardiotis E; De Jager P; Delgado S; Dubois B; Engel S; Esposito F; Fabis-Pedrini M; Filippi M; Fitzgerald K; Gasperi C; Gomez L; Gomez R; Hadjigeorgiou G; Hamann J; Held F; Henry R; Hillert J; Huang J; Huitinga I; Islam T; Isobe N; Jagodic M; Kermode AL; Khalil M; Kilpatrick T; Konidari I; Kreft K; Lechner-Scott J; Leone M; Luessi F; Malhotra S; Manouchehrinia A; Manrique C; Martinelli-Boneschi F; Martinez A; Martinez-Maldonado V; Mascia E; Metz L; Midaglia L; Montalban X; Oksenberg J; Olsson T; Oturai A; Paakkonen K; Parnell GP; Patsopoulos N; Pericak-Vance M; Piehl F; Rubio J; Santaniello A; Santoro S; Schaefer C; Sellebjerg F; Shams H; Shchetynsky K; Silva C; Siokas V; Sondergaard H; Sorosina M; Taylor B; Vandebergh M; Vasileiou E; Vecchio D; Voortman M; Weiner H; Wever D; Yong VW; Hafler D; Stewart G; Compston A; Zipp F; Harbo H; Hemmer B; Goris A; Smolders J; Hauser S; Kockum I; Sawcer S; Baranzini S; Jonsdottir I; Blanco Y; Llufriu S; Madireddy L; Saiz A; Villoslada P; Stefansson K; Harbo HF; Hemmer B; Goris A; Kockum I; Sawcer SJ; Baranzini SE
Article: NEUROLOGY: NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2023;10(1):e200056
Sustained Low Relapse Rate With Highly Variable B-Cell Repopulation Dynamics With Extended Rituximab Dosing Intervals in Multiple Sclerosis
Starvaggi Cucuzza C; Longinetti E; Ruffin N; Evertsson B; Kockum I; Jagodic M; Al Nimer F; Frisell T; Piehl F
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1251772
Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing
Kalomoiri M; Prakash CR; Lagstroem S; Hauschulz K; Ewing E; Shchetynsky K; Kular L; Needhamsen M; Jagodic M
Article: EPIGENETICS. 2022;17(11):1311-1330
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients
Kular L; Ewing E; Needhamsen M; Kakhki MP; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Article: EPIGENETICS. 2022;17(10):1195-1204
Comparison of EM-seq and PBAT methylome library methods for low-input DNA
Han Y; Zheleznyakova GY; Marincevic-Zuniga Y; Kakhki MP; Raine A; Needhamsen M; Jagodic M
Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2022;9:916128
RNA-sequencing and mass-spectrometry proteomic time-series analysis of T-cell differentiation identified multiple splice variants models that predicted validated protein biomarkers in inflammatory diseases
Magnusson R; Rundquist O; Kim MJ; Hellberg S; Na CH; Benson M; Gomez-Cabrero D; Kockum I; Tegner JN; Piehl F; Jagodic M; Mellergard J; Altafini C; Ernerudh J; Jenmalm MC; Nestor CE; Kim M-S; Gustafsson M
Article: FRONTIERS IN GENETICS. 2022;13:1042483
Integration of small RNAs from plasma and cerebrospinal fluid for classification of multiple sclerosis
Needhamsen M; Khoonsari PE; Zheleznyakova GY; Piket E; Hagemann-Jensen M; Han Y; Gierlich J; Ekman D; Jagodic M
Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:926468
Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients
Kular L; Klose D; Urdanoz-Casado A; Ewing E; Planell N; Gomez-Cabrero D; Needhamsen M; Jagodic M
Article: EPIGENOMICS. 2021;13(20):1607-1618
Deep characterization of paired chromatin and transcriptomes in four immune cell types from multiple sclerosis patients
Fernandes SJ; Ericsson M; Khademi M; Jagodic M; Olsson T; Gomez-Cabrero D; Kockum I; Tegner J
Article: BMC GENOMICS. 2021;22(1):631
A validated generally applicable approach using the systematic assessment of disease modules by GWAS reveals a multi-omic module strongly associated with risk factors in multiple sclerosis
Badam TVS; de Weerd HA; Martinez-Enguita D; Olsson T; Alfredsson L; Kockum I; Jagodic M; Lubovac-Pilav Z; Gustafsson M
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026
Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Jagodic M; Ekstrom TJ; Ockinger J; Kular L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(17):e2011574118
Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology
Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Han Y; James T; Khademi M; Al Nimer F; Scicluna P; Huang J; Kockum I; Faridani OR; Olsson T; Piehl F; Jagodic M
Article: FRONTIERS IN GENETICS. 2021;12:620453
STATegra: Multi-Omics Data Integration - A Conceptual Scheme With a Bioinformatics Pipeline
Planell N; Lagani V; Sebastian-Leon P; van der Kloet F; Ewing E; Karathanasis N; Urdangarin A; Arozarena I; Jagodic M; Tsamardinos I; Tarazona S; Conesa A; Tegner J; Gomez-Cabrero D
Article: SCIENCE IMMUNOLOGY. 2020;5(52):eabb5077
Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation.
Berglund R; Guerreiro-Cacais AO; Adzemovic MZ; Zeitelhofer M; Lund H; Ewing E; Ruhrmann S; Nutma E; Parsa R; Thessen-Hedreul M; Amor S; Harris RA; Olsson T; Jagodic M
Article: BMC BIOINFORMATICS. 2020;21(1):443
GeneSetCluster: a tool for summarizing and integrating gene-set analysis results
Ewing E; Planell-Picola N; Jagodic M; Gomez-Cabrero D
Article: NATURE COMMUNICATIONS. 2020;11(1):4071
Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis
Carlstrom KE; Zhu K; Ewing E; Krabbendam IE; Harris RA; Falcao AM; Jagodic M; Castelo-Branco G; Piehl F
Article: EPIGENETICS. 2020;15(6-7):646-663
Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression
Ciuculete DM; Voisin S; Kular L; Welihinda N; Jonsson J; Jagodic M; Mwinyi J; Schioth HB
Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(2):838-852
C-type lectin receptors Mcl and Mincle contro development of multiple sclerosis like neuroinflammation
N'diaye M; Brauner S; Flytzani S; Kular L; Warnecke A; Adzemovic MZ; Piket E; Min J-H; Edwards W; Mela F; Choi HY; Magg V; James T; Linden M; Reichardt HM; Daws MR; van Horssen J; Kockum I; Harris RA; Olsson T; Guerreiro-Cacais AO; Jagodic M
Article: FRONTIERS IN NEUROLOGY. 2020;11:600401
Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (Mhc2ta)
Hochmeister S; Aeinehband S; Dorris C; Berglund R; Haindl MT; Velikic V; Gustafsson SA; Olsson T; Piehl F; Jagodic M; Zeitelhofer M; Adzemovic MZ
Article: SCIENCE. 2019;365(6460):eaav7188
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Patsopoulos NA; Baranzini SE; Santaniello A; Shoostari P; Cotsapas C; Wong G; Beecham AH; James T; Replogle J; Vlachos IS; McCabe C; Pers TH; Brandes A; White C; Keenan B; Cimpean M; Winn P; Panteliadis I-P; Robbins A; Andlauer TFM; Zarzycki O; Dubois B; Goris A; Sondergaard HB; Sellebjerg F; Sorensen PS; Ullum H; Thorner LW; Saarela J; Cournu-Rebeix I; Damotte V; Fontaine B; Guillot-Noel L; Lathrop M; Vukusic S; Berthele A; Pongratz V; Pongratz V; Gasperi C; Graetz C; Grummel V; Hemmer B; Hoshi M; Knier B; Korn T; Lill CM; Luessi F; Muehlau M; Zipp F; Dardiotis E; Agliardi C; Amoroso A; Barizzone N; Benedetti MD; Bernardinelli L; Cavalla P; Clarelli F; Comi G; Cusi D; Esposito F; Ferre L; Galimberti D; Guaschino C; Leone MA; Martinelli V; Moiola L; Salvetti M; Sorosina M; Vecchio D; Zauli A; Santoro S; Mancini N; Zuccala M; Mescheriakova J; van Duijn C; Bos SD; Celius EG; Spurkland A; Comabella M; Montalban X; Alfredsson L; Bomfim IL; Gomez-Cabrero D; Hillert J; Jagodic M; Linden M; Piehl F; Jelcic I; Martin R; Sospedra M; Baker A; Ban M; Hawkins C; Hysi P; Kalra S; Karpe F; Khadake J; Lachance G; Molyneux P; Neville M; Thorpe J; Bradshaw E; Caillier SJ; Calabresi P; Cree BAC; Cross A; Davis M; de Bakker PWI; Delgado S; Dembele M; Edwards K; Fitzgerald K; Frohlich IY; Gourraud P-A; Haines JL; Hakonarson H; Kimbrough D; Isobe N; Konidari I; Lathi E; Lee MH; Li T; An D; Zimmer A; Madireddy L; Manrique CP; Mitrovic M; Olah M; Patrick E; Pericak-Vance MA; Piccio L; Schaefer C; Weiner H; Lage K; Scott RJ; Lechner-Scott J; Leal R; Moscato P; Booth DR; Stewart GJ; Vucic S; Pame G; BamettO M; Mason D; GriffithS L; Broadley S; Tajouri L; Baxter A; Slee M; Taylor BV; Charlesworth J; Kilpatrick TJ; Rubio J; Jokubaitis V; Wiley J; Butzkueven H; Leslie S; Motyer A; Stankovich J; Carroll WM; Kermode AG; Edrin M; Barclay M; Peyrin-Biroulet L; Chamaillard M; Colombe J-F; Cottone M; Croft A; D'Inca R; Halfvarson J; Hanigan K; Henderson P; Hugot J-P; Karban A; Kennedy NA; Khan MA; Lemann M; Levine A; Massey D; Milla M; Motoey GW; Ng SME; Oikonomnou J; Peeters H; Proctor DD; Rahier J-F; Roberts R; Rutgeerts P; Seibold F; Stronati L; Taylor KM; Torkvist L; Ublick K; Van Limbergen J; Van Gossum A; Vatn MH; Zhang H; Zhang W; Donnelly P; Barroso I; Blackwe JM; Bramon E; Brown MA; Casas JP; Corvin A; Deloukas P; Duncanson A; Jankowski J; Markus HS; Mathew CG; Palmer CNA; Plomin R; Rautanen A; Sawcer SJ; Trembath RC; Viswanathan AC; Wood NW; Spencer CCA; Band G; Bellenguez C; Freeman C; Hellenthal G; Giannoulatou E; Pirinen M; Pearson R; Strange A; Sul Z; Vukcevic DA; Donnelly P; Langford C; Hunt SE; Edkins S; Gwilliam R; Blackburn H; Bumpstead SJ; Dronov S; Gillman M; Gray E; Hammond N; Jayakumar A; McCann OT; Liddle J; Potter SC; Ravindrarajah R; Ricketts M; Waller M; Weston P; Widaa S; Whittaker P; Barroso I; Deloukas P; Mathew CG; Blackwe JM; Brown MA; Corvin A; Spencer CCA; Compston A; Hafler D; Harbo HF; Hauser SL; Stewart G; D'Alfonso S; Hadjigeorgiou G; Taylor B; Barcellos LF; Booth D; Hintzen R; Kockum I; Martinelli-Boneschi F; McCauley JL; Oksenberg JR; Oturai A; Sawcer S; Ivinson AJ; Olsson T; De Jager PL
Article: EPIGENOMICS. 2019;11(12):1429-1439
Different epigenetic clocks reflect distinct pathophysiological features of multiple sclerosis
Theodoropoulou E; Alfredsson L; Piehl F; Marabita F; Jagodic M
Article: SCIENTIFIC REPORTS. 2019;9(1):11996
Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients
Fernandes SJ; Morikawa H; Ewing E; Ruhrmann S; Joshi RN; Lagani V; Karathanasis N; Khademi M; Planell N; Schmidt A; Tsamardinos I; Olsson T; Piehl F; Kockum I; Jagodic M; Tegner J; Gomez-Cabrero D
Article: JOURNAL OF IMMUNOLOGY. 2019;203(4):888-898
IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
Lindahl H; Guerreiro-Cacais AO; Bedri SK; Linnerbauer M; Linden M; Abdelmagid N; Tandre K; Hollins C; Irving L; Glover C; Jones C; Alfredsson L; Ronnblom L; Kockum I; Khademi M; Jagodic M; Olsson T
Article: EBIOMEDICINE. 2019;46:290-304
Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells
Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjoholm LK; Slavec L; Kullberg S; Wahlstrom J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Ockinger J; Ekstrom TJ
Article: NATURE COMMUNICATIONS. 2019;10(1):3081
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
Carlstrom KE; Ewing E; Granqvist M; Gyllenberg A; Aeinehband S; Enoksson SL; Checa A; Badam TVS; Huang J; Gomez-Cabrero D; Gustafsson M; Al Nimer F; Wheelock CE; Kockum I; Olsson T; Jagodic M; Piehl F
Article: JOURNAL OF AUTOIMMUNITY. 2019;101:17-25
Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview
Piket E; Zheleznyakova GY; Kular L; Jagodic M
Article: CLINICAL EPIGENETICS. 2019;11(1):86
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(19):9443-9452
Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration
Li D; Kular L; Vij M; Herter EK; Li X; Wang A; Chu T; Toma M-A; Zhang L; Liapi E; Mota A; Blomqvist L; Serezal IG; Rollman O; Wikstrom JD; Bienko M; Berglund D; Stahle M; Sommar P; Jagodic M; Landen NX
Article: EBIOMEDICINE. 2019;43:411-423
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
Ewing E; Kular L; Fernandes SJ; Karathanasis N; Lagani V; Ruhrmann S; Tsamardinos I; Tegner J; Piehl F; Gomez-Cabrero D; Jagodic M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49(2):313-322
miR-31 regulates energy metabolism and is suppressed in Tcells from patients with Sjogren's syndrome
Johansson A; Nyberg WA; Sjostrand M; Moruzzi N; Bergman P; Khademi M; Andersson M; Piehl F; Berggren P-O; Covacu R; Jagodic M; Espinosa A
Article: NATURE COMMUNICATIONS. 2018;9(1):4845
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
Lund H; Pieber M; Parsa R; Han J; Grommisch D; Ewing E; Kular L; Needhamsen M; Espinosa A; Nilsson E; Overby AK; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: MULTIPLE SCLEROSIS JOURNAL. 2018;24(10):1288-1300
Hypermethylation of MIR21 in CD4+T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes
Ruhrmann S; Ewing E; Piket E; Kular L; Lorenzi JCC; Fernandes SJ; Morikawa H; Aeinehband S; Sayols-Baixeras S; Aslibekyan S; Absher DM; Arnett DK; Tegner J; Gomez-Cabrero D; Piehl F; Jagodic M
Article: NEUROLOGY: NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2018;5(5):e491
Identification of MS-specific serum miRNAs in an international multicenter study
Regev K; Healy BC; Paul A; Diaz-Cruz C; Mazzola MA; Raheja R; Glanz BI; Kivisakk P; Chitnis T; Jagodic M; Piehl F; Olsson T; Khademi M; Hauser S; Oksenberg J; Khoury SJ; Weiner HL; Gandhi R
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2018;102:44-51
Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents
Ciuculete DM; Bostrom AE; Tuunainen A-K; Sohrabi F; Kular L; Jagodic M; Voisin S; Mwinyi J; Schioth HB
Article: NATURE COMMUNICATIONS. 2018;9(1):2397
DNA methylation as a mediator of HLA-DRB1^☆15:01 and a protective variant in multiple sclerosis
Kular L; Liu Y; Ruhrmann S; Zheleznyakova G; Marabita F; Gomez-Cabrero D; James T; Ewing E; Linden M; Gornikiewicz B; Aeinehband S; Stridh P; Link J; Andlauer TFM; Gasperi C; Wiendl H; Zipp F; Gold R; Tackenberg B; Weber F; Hemmer B; Strauch K; Heilmann-Heimbach S; Rawal R; Schminke U; Schmidt CO; Kacprowski T; Franke A; Laudes M; Dilthey AT; Celius EG; Sondergaard HB; Tegner J; Harbo HF; Oturai AB; Olafsson S; Eggertsson HP; Halldorsson BV; Hjaltason H; Olafsson E; Jonsdottir I; Stefansson K; Olsson T; Piehl F; Ekstroem TJ; Kockum I; Feinberg AP; Jagodic M
Article: NATURE IMMUNOLOGY. 2018;19(5):1-7
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: MOLECULAR THERAPY. 2018;26(4):1040-1055
Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions
Jin H; Li DY; Chernogubova E; Sun C; Busch A; Eken SM; Saliba-Gustafsson P; Winter H; Winski G; Raaz U; Schellinger IN; Simon N; Hegenloh R; Matic LP; Jagodic M; Ehrenborg E; Pelisek J; Eckstein H-H; Hedin U; Backlund A; Maegdefessel L
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(4):882-892
Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis
Lohcharoenkal W; Das Mahapatra K; Pasquali L; Crudden C; Kular L; Ulum YZA; Zhang L; Landen NX; Girnita L; Jagodic M; Stahle M; Sonkoly E; Pivarcsi A
Article: HUMAN MOLECULAR GENETICS. 2018;27(5):912-928
Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients
James T; Linden M; Morikawa H; Fernandes SJ; Ruhrmann S; Huss M; Brandi M; Piehl F; Jagodic M; Tegner J; Khademi M; Olsson T; Gomez-Cabrero D; Kockum I
Article: BMC BIOINFORMATICS. 2017;18(1):486
Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies
Needhamsen M; Ewing E; Lund H; Gomez-Cabrero D; Harris RA; Kular L; Jagodic M
Article: SCIENTIFIC REPORTS. 2017;7(1):14589
Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship
Marabita F; Almgren M; Sjoholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekstrom TJ; Jagodic M
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):71
DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis
Meng W; Zhu Z; Jiang X; Too CL; Uebe S; Jagodic M; Kockum I; Murad S; Ferrucci L; Alfredsson L; Zou H; Klareskog L; Feinberg AP; Ekstrom TJ; Padyukov L; Liu Y
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(9):E1678-E1687
Functional genomics analysis of vitamin D effects on CD4+T cells in vivo in experimental autoimmune encephalomyelitis
Zeitelhofer M; Adzemovic MZ; Gomez-Cabrero D; Bergman P; Hochmeister S; N'diaye M; Paulson A; Ruhrmann S; Almgren M; Tegner JN; Ekstrom TJ; Guerreiro-Cacais AO; Jagodic M
Article: GENES AND IMMUNITY. 2017;18(1):48-56
VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis
Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2016;213(8):1537-1553
BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis
Parsa R; Lund H; Georgoudaki A-M; Zhang X-M; Guerreiro-Cacais AO; Grommisch D; Warnecke A; Croxford AL; Jagodic M; Becher B; Karlsson MCI; Harris RA
Article: NEUROLOGY: NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2016;3(3):e219
Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis
Bergman P; Piket E; Khademi M; James T; Brundin L; Olsson T; Piehl F; Jagodic M
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2016;99(3):437-446
Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics
N'diaye M; Warnecke A; Flytzani S; Abdelmagid N; Ruhrmann S; Olsson T; Jagodic M; Harris RA; Guerreiro-Cacais AO
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1304:3-24
Positional Gene Cloning in Experimental Populations.
Jagodic M; Stridh P
Article: JOURNAL OF NEUROINFLAMMATION. 2015;12:194
MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated
Flytzani S; Guerreiro-Cacais AO; N'diaye M; Lindner M; Linington C; Meinl E; Stridh P; Jagodic M; Olsson T
Article: NEUROBIOLOGY OF DISEASE. 2014;71:220-233
Acute treatment with valproic acid and L-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats
Castelo-Branco G; Stridh P; Guerreiro-Cacais AO; Adzemovic MZ; Falcao AM; Marta M; Berglund R; Gillett A; Hamza KH; Lassmann H; Hermanson O; Jagodic M
Article: GENES AND IMMUNITY. 2014;15(7):457-465
The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation
Laaksonen H; Guerreiro-Cacais AO; Adzemovic MZ; Parsa R; Zeitelhofer M; Jagodic M; Olsson T
Article: BMC GENOMICS. 2014;15(1):391
Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research
Backdahl L; Ekman D; Jagodic M; Olsson T; Holmdahl R
Article: PLOS GENETICS. 2014;10(3):e1004265
Parent-of-Origin Effects Implicate Epigenetic Regulation of Experimental Autoimmune Encephalomyelitis and Identify Imprinted Dlk1 as a Novel Risk Gene
Stridh P; Ruhrmann S; Bergman P; Hedreul MT; Flytzani S; Beyeen AD; Gillett A; Krivosija N; Ockinger J; Ferguson-Smith AC; Jagodic M
Article: PLOS GENETICS. 2014;10(2):e1004151
Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat
Tuncel J; Haag S; Yau ACY; Norin U; Baud A; Lonnblom E; Maratou K; Ytterberg AJ; Ekman D; Thordardottir S; Johannesson M; Gillett A; Stridh P; Jagodic M; Olsson T; Fernandez-Teruel A; Zubarev RA; Mott R; Aitman TJ; Flint J; Holmdahl R
Article: SCIENTIFIC DATA. 2014;1:140011
Genomes and phenomes of a population of outbred rats and its progenitors
Baud A; Guryev V; Hummel O; Johannesson M; Flint J
Article: HUMAN MOLECULAR GENETICS. 2013;22(24):4952-4966
Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity
Hedreul MT; Moeller S; Stridh P; Gupta Y; Gillett A; Beyeen AD; Oeckinger J; Flytzani S; Diez M; Olsson T; Jagodic M
Article: NATURE GENETICS. 2013;45(11):1353-1360
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Beecham AH; Patsopoulos NA; Xifara DK; Davis MF; Kemppinen A; Cotsapas C; Shah TS; Spencer C; Booth D; Goris A; Oturai A; Saarela J; Fontaine B; Hemmer B; Martin C; Zipp F; D'Alfonso S; Martinelli-Boneschi F; Taylor B; Harbo HF; Kockum I; Hillert J; Olsson T; Ban M; Oksenberg JR; Hintzen R; Barcellos LF; Agliardi C; Alfredsson L; Alizadeh M; Anderson C; Andrews R; Sondergaard HB; Baker A; Band G; Baranzini SE; Barizzone N; Barrett J; Bellenguez C; Bergamaschi L; Bernardinelli L; Berthele A; Biberacher V; Binder TMC; Blackburn H; Bomfim IL; Brambilla P; Broadley S; Brochet B; Brundin L; Buck D; Butzkueven H; Caillier SJ; Camu W; Carpentier W; Cavalla P; Celius EG; Coman I; Comi G; Corrado L; Cosemans L; Cournu-Rebeix I; Cree BAC; Cusi D; Damotte V; Defer G; Delgado SR; Deloukas P; di Sapio A; Dilthey AT; Donnelly P; Dubois B; Duddy M; Edkins S; Elovaara I; Esposito F; Evangelou N; Fiddes B; Field J; Franke A; Freeman C; Frohlich IY; Galimberti D; Gieger C; Gourraud P-A; Graetz C; Graham A; Grummel V; Guaschino C; Hadjixenofontos A; Hakonarson H; Halfpenny C; Hall G; Hall P; Hamsten A; Harley J; Harrower T; Hawkins C; Hellenthal G; Hillier C; Hobart J; Hoshi M; Hunt SE; Jagodic M; Jelcic I; Jochim A; Kendall B; Kermode A; Kilpatrick T; Koivisto K; Konidari I; Korn T; Kronsbein H; Langford C; Larsson M; Lathrop M; Lebrun-Frenay C; Lechner-Scott J; Lee MH; Leone MA; Leppa V; Liberatore G; Lie BA; Lill CM; Linden M; Link J; Luessi F; Lycke J; Macciardi F; Mannisto S; Manrique CP; Martin R; Martinelli V; Mason D; Mazibrada G; McCabe C; Mero I-L; Mescheriakova J; Moutsianas L; Myhr K-M; Nagels G; Nicholas R; Nilsson P; Piehl F; Pirinen M; Price SE; Quach H; Reunanen M; Robberecht W; Robertson NP; Rodegher M; Rog D; Salvetti M; Schnetz-Boutaud NC; Sellebjerg F; Selter RC; Schaefer C; Shaunak S; Shen L; Shields S; Siffrin V; Slee M; Sorensen PS; Sorosina M; Sospedra M; Spurkland A; Strange A; Sundqvist E; Thijs V; Thorpe J; Ticca A; Tienari P; van Duijn C; Visser EM; Vucic S; Westerlind H; Wiley JS; Wilkins A; Wilson JF; Winkelmann J; Zajicek J; Zindler E; Haines JL; Pericak-Vance MA; Ivinson AJ; Stewart G; Hafler D; Hauser SL; Compston A; McVean G; De Jager P; Sawcer SJ; McCauley JL
Article: EXPERIMENTAL NEUROLOGY. 2013;249:39-48
Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage
Adzemovic MZ; Zeitelhofer M; Hochmeister S; Gustafsson SA; Jagodic M
Article: GENES AND IMMUNITY. 2013;14(7):409-419
Anti-MOG antibodies are under polygenic regulation with the most significant control coming from the C-type lectin-like gene locus
Flytzani S; Stridh P; Guerreiro-Cacais AO; Marta M; Hedreul MT; Jagodic M; Olsson T
Article: NATURE GENETICS. 2013;45(7):767-775
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats
Baud A; Hermsen R; Guryev V; Stridh P; Graham D; McBride MW; Foroud T; Calderari S; Diez M; Ockinger J; Beyeen AD; Gillett A; Abdelmagid N; Guerreiro-Cacais AO; Jagodic M; Tuncel J; Norin U; Beattie E; Ngan H; Miller WH; Koller DL; Alam I; Falak S; Osborne-Pellegrin M; Martinez-Membrives E; Canete T; Blazquez G; Vicens-Costa E; Mont-Cardona C; Diaz-Moran S; Tobena A; Hummel O; Zelenika D; Saar K; Patone G; Bauerfeind A; Bihoreau M-T; Heinig M; Lee Y-A; Rintisch C; Schulz H; Wheeler DA; Worley KC; Muzny DM; Gibbs RA; Lathrop M; Lansu N; Toonen P; Ruzius FP; de Bruijn E; Hauser H; Adams DJ; Keane T; Atanur SS; Aitman TJ; Flicek P; Malinauskas T; Jones EY; Ekman D; Lopez-Aumatell R; Dominiczak AF; Johannesson M; Holmdahl R; Olsson T; Gauguier D; Hubner N; Fernandez-Teruel A; Cuppen E; Mott R; Flint J
Article: MULTIPLE SCLEROSIS JOURNAL. 2013;19(7):863-870
Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13
Linden M; Khademi M; Bomfim IL; Piehl F; Jagodic M; Kockum I; Olsson T
Article: JOURNAL OF IMMUNOLOGY. 2013;190(8):4066-4075
Next-Generation Sequencing Identifies MicroRNAs that Associate with Pathogenic Autoimmune Neuroinflammation in Rats
Bergman P; James T; Kular L; Ruhrmann S; Kramarova T; Kvist A; Supic G; Gillett A; Pivarcsi A; Jagodic M
Article: EPIGENETICS. 2013;8(3):333-346
An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
Marabita F; Almgren M; Lindholm ME; Ruhrmann S; Fagerstrom-Billai F; Jagodic M; Sundberg CJ; Ekstrom TJ; Teschendorff AE; Tegner J; Gomez-Cabrero D
Article: PLOS ONE. 2013;8(12):e81912
A Silent Exonic SNP in Kdm3a Affects Nucleic Acids Structure but Does Not Regulate Experimental Autoimmune Encephalomyelitis
Gillett A; Bergman P; Parsa R; Bremges A; Giegerich R; Jagodic M
Article: PLOS ONE. 2013;8(5):e63300
A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis
Mechelli R; Umeton R; Policano C; Annibali V; Coarelli G; Ricigliano VAG; Vittori D; Fornasiero A; Buscarinu MC; Romano S; Salvetti M; Ristori G
Article: EPIGENETICS. 2012;7(6):585-593
Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity
Esteki-Zadeh A; Karimi M; Straat K; Ammerpohl O; Zeitelhofer M; Jagodic M; Mehrab-Mohseni M; Sjoholm L; Rahbar A; Soderberg-Naucler C; Ekstrom TJ
Article: PLOS ONE. 2012;7(7):e39794
Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats
Adzemovic MZ; Ockinger J; Zeitelhofer M; Hochmeister S; Beyeen AD; Paulson A; Gillett A; Hedreul MT; Covacu R; Lassmann H; Olsson T; Jagodic M
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2011;208(11):2183-2191
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development
Colacios C; Casemayou A; Dejean AS; Gaits-Iacovoni F; Pedros C; Bernard I; Lagrange D; Deckert M; Lamouroux L; Jagodic M; Olsson T; Liblau RS; Fournie GJ; Saoudi A
Article: NATURE. 2011;476(7359):214-219
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Sawcer S; Hellenthal G; Pirinen M; Spencer CCA; Patsopoulos NA; Moutsianas L; Dilthey A; Su Z; Freeman C; Hunt SE; Edkins S; Gray E; Booth DR; Potter SC; Goris A; Band G; Oturai AB; Strange A; Saarela J; Bellenguez C; Fontaine B; Gillman M; Hemmer B; Gwilliam R; Zipp F; Jayakumar A; Martin R; Leslie S; Hawkins S; Giannoulatou E; D'alfonso S; Blackburn H; Boneschi FM; Liddle J; Harbo HF; Perez ML; Spurkland A; Waller MJ; Mycko MP; Ricketts M; Comabella M; Hammond N; Kockum I; McCann OT; Ban M; Whittaker P; Kemppinen A; Weston P; Hawkins C; Widaa S; Zajicek J; Dronov S; Robertson N; Bumpstead SJ; Barcellos LF; Ravindrarajah R; Abraham R; Alfredsson L; Ardlie K; Aubin C; Baker A; Baker K; Baranzini SE; Bergamaschi L; Bergamaschi R; Bernstein A; Berthele A; Boggild M; Bradfield JP; Brassat D; Broadley SA; Buck D; Butzkueven H; Capra R; Carroll WM; Cavalla P; Celius EG; Cepok S; Chiavacci R; Clerget-Darpoux F; Clysters K; Comi G; Cossburn M; Cournu-Rebeix I; Cox MB; Cozen W; Cree BAC; Cross AH; Cusi D; Daly MJ; Davis E; de Bakker PIW; Debouverie M; D'hooghe MB; Dixon K; Dobosi R; Dubois B; Ellinghaus D; Elovaara I; Esposito F; Fontenille C; Foote S; Franke A; Galimberti D; Ghezzi A; Glessner J; Gomez R; Gout O; Graham C; Grant SFA; Guerini FR; Hakonarson H; Hall P; Hamsten A; Hartung H-P; Heard RN; Heath S; Hobart J; Hoshi M; Infante-Duarte C; Ingram G; Ingram W; Islam T; Jagodic M; Kabesch M; Kermode AG; Kilpatrick TJ; Kim C; Klopp N; Koivisto K; Larsson M; Lathrop M; Lechner-Scott JS; Leone MA; Leppa V; Liljedahl U; Bomfim IL; Lincoln RR; Link J; Liu J; Lorentzen AR; Lupoli S; Macciardi F; Mack T; Marriott M; Martinelli V; Mason D; McCauley JL; Mentch F; Mero I-L; Mihalova T; Montalban X; Mottershead J; Myhr K-M; Naldi P; Ollier W; Page A; Palotie A; Pelletier J; Piccio L; Pickersgill T; Piehl F; Pobywajlo S; Quach HL; Ramsay PP; Reunanen M; Reynolds R; Rioux J; Rodegher M; Roesner S; Rubio JP; Rueckert I-M; Salvetti M; Salvi E; Santaniello A; Schaefer CA; Schreiber S; Schulze C; Scott RJ; Sellebjerg F; Selmaj KW; Sexton D; Shen L; Simms-Acuna B; Skidmore S; Sleiman PMA; Smestad C; Sorensen PS; Sondergaard HB; Stankovich J; Strange RC; Sulonen A-M; Sundqvist E; Syvaenen A-C; Taddeo F; Taylor B; Blackwell JM; Tienari P; Bramon E; Tourbah A; Brown MA; Tronczynska E; Casas JP; Tubridy N; Corvin A; Vickery J; Jankowski J; Villoslada P; Markus HS; Wang K; Mathew CG; Wason J; Palmer CNA; Wichmann H-E; Plomin R; Willoughby E; Rautanen A; Winkelmann J; Wittig M; Trembath RC; Yaouanq J; Viswanathan AC; Zhang H; Wood NW; Zuvich R; Deloukas P; Langford C; Duncanson A; Oksenberg JR; Pericak-Vance MA; Haines JL; Olsson T; Hillert J; Ivinson AJ; De Jager PL; Peltonen L; Stewart GJ; Hafler DA; Hauser SL; McVean G; Donnelly P; Compston A
Article: JOURNAL OF IMMUNOLOGY. 2010;185(11):6883-6890
IL-22RA2 Associates with Multiple Sclerosis and Macrophage Effector Mechanisms in Experimental Neuroinflammation
Beyeen AD; Adzemovic MZ; Ockinger J; Stridh P; Becanovic K; Laaksonen H; Lassmann H; Harris RA; Hillert J; Alfredsson L; Celius EG; Harbo HF; Kockum I; Jagodic M; Olsson T
Article: PLOS ONE. 2010;5(9):e12716
Fine-Mapping Resolves Eae23 into Two QTLs and Implicates ZEB1 as a Candidate Gene Regulating Experimental Neuroinflammation in Rat
Stridh P; Hedreul MT; Beyeen AD; Adzemovic MZ; Laaksonen H; Gillett A; Ockinger J; Marta M; Lassmann H; Becanovic K; Jagodic M; Olsson T
Article: JOURNAL OF IMMUNOLOGY. 2010;185(6):3574-3582
Maternal MHC Regulates Generation of Pathogenic Antibodies and Fetal MHC-Encoded Genes Determine Susceptibility in Congenital Heart Block
Strandberg LS; Ambrosi A; Jagodic M; Dzikaite V; Janson P; Khademi M; Salomonsson S; Ottosson L; Klauninger R; Aden U; Sonesson S-E; Sunnerhagen M; de Graaf KL; Kuchroo VK; Achour A; Winqvist O; Olsson T; Wahren-Herlenius M
Article: MULTIPLE SCLEROSIS JOURNAL. 2010;16(9):1056-1065
Interleukin 18 Receptor 1 expression distinguishes patients with multiple sclerosis
Gillett A; Hedreul MT; Khademi M; Espinosa A; Beyeen AD; Jagodic M; Kockum I; Harris RA; Olsson T
Article: JOURNAL OF IMMUNOLOGY. 2010;185(1):442-450
TNF Production in Macrophages Is Genetically Determined and Regulates Inflammatory Disease in Rats
Gillett A; Marta M; Jin T; Tuncel J; Leclerc P; Nohra R; Lange S; Holmdahl R; Olsson T; Harris RA; Jagodic M
Article: GENES AND IMMUNITY. 2010;11(4):279-293
RGMA and IL21R show association with experimental inflammation and multiple sclerosis
Nohra R; Beyeen AD; Guo JP; Khademi M; Sundqvist E; Hedreul M; Sellebjerg F; Smestad C; Oturai AB; Harbo HF; Wallstrom E; Hillert J; Alfredsson L; Kockum I; Jagodic M; Lorentzen J; Olsson T
Article: MOLECULAR AND CELLULAR BIOLOGY. 2010;30(5):1199-1216
Mutational Analysis of the Poly(ADP-Ribosyl)ation Sites of the Transcription Factor CTCF Provides an Insight into the Mechanism of Its Regulation by Poly(ADP-Ribosyl)ation
Farrar D; Rai S; Chernukhin I; Jagodic M; Ito Y; Yammine S; Ohlsson R; Murrell A; Klenova E
Article: GENES AND IMMUNITY. 2010;11(2):142-154
Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis
Ockinger J; Stridh P; Beyeen AD; Lundmark F; Seddighzadeh M; Oturai A; Sorensen PS; Lorentzen AR; Celius EG; Leppa V; Koivisto K; Tienari PJ; Alfredsson L; Padyukov L; Hillert J; Kockum I; Jagodic M; Olsson T
Article: GENES AND IMMUNITY. 2010;11(1):21-36
Multiple loci comprising immune-related genes regulate experimental neuroinflammation
Marta M; Stridh P; Becanovic K; Gillett A; Ockinger J; Lorentzen JC; Jagodic M; Olsson T
Article: SCIENCE TRANSLATIONAL MEDICINE. 2009;1(10):10ra21
A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
Jagodic M; Colacios C; Nohra R; Dejean AS; Beyeen AD; Khademi M; Casemayou A; Lamouroux L; Duthoit C; Papapietro O; Sjoholm L; Bernard I; Lagrange D; Dahlman I; Lundmark F; Oturai AB; Soendergaard HB; Kemppinen A; Saarela J; Tienari PJ; Harbo HF; Spurkland A; Ramagopalan SV; Sadovnick DA; Ebers GC; Seddighzadeh M; Klareskog L; Alfredsson L; Padyukov L; Hillert J; Clanet M; Edan G; Fontaine B; Fournie GJ; Kockum I; Saoudi A; Olsson T
Article: ANNALS OF THE RHEUMATIC DISEASES. 2009;68(12):1925-1932
Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data
Backdahl L; Guo JP; Jagodic M; Becanovic K; Ding B; Olsson T; Lorentzen JC
Article: PLOS ONE. 2009;4(11):e7773
Alternative Splicing and Transcriptome Profiling of Experimental Autoimmune Encephalomyelitis Using Genome-Wide Exon Arrays
Gillett A; Maratou K; Fewings C; Harris RA; Jagodic M; Aitman T; Olsson T
Article: JOURNAL OF NEUROIMMUNOLOGY. 2009;212(1-2):82-92
Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury
Diez M; Abdelmagid N; Harnesk K; Strom M; Lidman O; Swanberg M; Lindblom R; Al-Nimer F; Jagodic M; Olsson T; Piehl F
Article: JOURNAL OF NEUROIMMUNOLOGY. 2009;210(1-2):30-39
Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis
Hedreul MT; Gillett A; Olsson T; Jagodic M; Harris RA
Article: JOURNAL OF IMMUNOLOGY. 2009;182(7):4432-4438
Advanced Intercross Line Mapping Suggests That Ncf1 (Ean6) Regulates Severity in an Animal Model of Guillain-Barre Syndrome
Huberle A; Beyeen AD; Ockinger J; Ayturan M; Jagodic M; de Graaf KL; Fissolo N; Marta M; Olofsson P; Hultqvist M; Holmdahl R; Olsson T; Weissert R
Article: HUMAN MOLECULAR GENETICS. 2008;17(17):2633-2643
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
Ito Y; Koessler T; Ibrahim AEK; Rai S; Vowler SL; Abu-Amero S; Silva A-L; Maia A-T; Huddleston JE; Uribe-Lewis S; Woodfine K; Jagodic M; Nativio R; Dunning A; Moore G; Klenova E; Bingham S; Pharoah PDP; Brenton JD; Beck S; Sandhu MS; Murrell A
Article: JOURNAL OF IMMUNOLOGY. 2006;177(11):7923-7929
Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice
Johansson MH; Taylor MA; Jagodic M; Tus K; Schatzle JD; Wakeland EK; Bennett M
Article: GENOMICS. 2006;88(6):737-744
Combined-cross analysis of genome-wide linkage scans for experimental autoimmune encephalomyelitis in rat
Jagodic M; Olsson T
Article: GENETICS. 2006;173(3):1539-1545
Definition of a 1.06-Mb region linked to neuroinflammation in humans, rats and mice
Ockinger J; Serrano-Fernandez P; Moeller S; Ibrahim SM; Olsson T; Jagodic M
Article: JOURNAL OF IMMUNOLOGY. 2006;176(10):6055-6064
Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis
Becanovic K; Jagodic M; Sheng JR; Dahlman I; Aboul-Enein F; Wallstrom E; Olofsson P; Holmdahl R; Lassmann H; Olsson T
Article: JOURNAL OF NEUROINFLAMMATION. 2005;2:26
Cytokine responses during chronic denervation
Ruohonen S; Khademi M; Jagodic M; Taskinen H-S; Olsson T; Roytta M
Article: NITRIC OXIDE - BIOLOGY AND CHEMISTRY. 2005;13(3):188-195
Effects of long term NOS inhibition on disease and the immune system in MOG induced EAE
Danilov AI; Jagodic M; Wiklund NP; Olsson T; Brundin L
Article: GENETICS. 2005;170(1):283-289
Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis
Sheng JR; Jagodic M; Dahlman I; Becanovic K; Nohra R; Marta M; Iacobaeus E; Olsson T; Wallström E
Article: NATURE GENETICS. 2005;37(5):486-494
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
Swanberg M; Lidman O; Padyukov L; Eriksson P; Åkesson E; Jagodic M; Lobell A; Khademi M; Borjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: JOURNAL OF IMMUNOLOGY. 2005;174(2):918-924
Resolution of a 16.8-mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyrelitis quantitative trait loci and evidence for epistasis
Jagodic M; Marta M; Becanovic K; Sheng JR; Nohra R; Olsson T; Lorentzen JC
Article: JOURNAL OF IMMUNOLOGY. 2004;173(2):1366-1373
An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci
Jagodic M; Becanovic K; Sheng JR; Wu XC; Bäckdahl L; Lorentzen JC; Wallström E; Olsson T
Article: JOURNAL OF NEUROTRAUMA. 2004;21(7):969-975
Distinct expression of TGF-β1 mRNA in the endo- and epineurium after nerve injury
Taskinen HS; Ruohonen S; Jagodic M; Khademi M; Olsson T; Röyttä M
Article: NEUROSCIENCE LETTERS. 2003;350(3):165-168
Myelin oligodendrocyte glycoprotein is expressed in the peripheral nervous system of rodents and primates
Pagany M; Jagodic M; Schubart A; Pham-Dinh D; Bachelin C; van Evercooren AB; Lachapelle F; Olsson T; Linington C
Article: JOURNAL OF NEUROIMMUNOLOGY. 2003;139(1-2):1-8
Genetic variation in myelin oligodendrocyte glycoprotein expression and susceptibility to experimental autoimmune encephalomyelitis
Pagany M; Jagodic M; Bourquin C; Olsson T; Linington C
Article: JOURNAL OF NEUROIMMUNOLOGY. 2002;132(1-2):11-17
Contralateral non-operated nerve to transected rat sciatic nerve shows increased expression of IL-1β, TGF-β1, TNF-α, and IL-10
Ruohonen S; Jagodi M; Khademi M; Taskinen HS; Ojala P; Olsson T; Röyttä M
Article: IMMUNOGENETICS. 2001;53(5):410-415
Congenic mapping confirms a locus on rat chromosome 10 conferring strong protection against myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis
Jagodic M; Kornek B; Weissert R; Lassmann H; Olsson T; Dahlman I
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Review: JOURNAL OF INTERNAL MEDICINE. 2020;288(1):82-102
Epigenetic insights into multiple sclerosis disease progression
Kular L; Jagodic M
Corrigendum: SCIENTIFIC REPORTS. 2018;8(1):4340
Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship (vol 7, 14589, 2017)
Marabita F; Almgren M; Sjoholm LK; Kular L; Liu Y; James T; Kiss NB; Feinberg AP; Olsson T; Kockum I; Alfredsson L; Ekstrom TJ; Jagodic M
Review: PHYSIOLOGICAL GENOMICS. 2017;49(9):447-461
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
Zheleznyakova GY; Piket E; Marabita F; Kakhki MP; Ewing E; Ruhrmann S; Needhamsen M; Jagodic M; Kular L
Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(5):444-446
IL-22 binding protein regulates murine skin inflammation
Lindahl H; Martini E; Brauner S; Nikamo P; Serezal IG; Guerreiro-Cacais AO; Jagodic M; Eidsmo L; Stahle M; Olsson T
Corrigendum: GENES AND IMMUNITY. 2017;18(2):109
VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis (vol 18, pg 48, 2017)
Guerreiro-Cacais AO; Norin U; Gyllenberg A; Berglund R; Beyeen AD; Petit-Teixeira E; Cornelis F; Saoudi A; Fournie GJ; Holmdahl R; Alfredsson L; Klareskog L; Jagodic M; Olsson T; Kockum I; Padyukov L
Review: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY. 2015;67:49-57
Genomic imprinting: A missing piece of the Multiple Sclerosis puzzle?
Ruhrmann S; Stridh P; Kular L; Jagodic M
Editorial comment: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2015;356(1-2):3-4
MicroRNAs as promising novel biomarkers and potential drug targets for inflammatory neurological diseases
Piehl F; Jagodic M
Review: JOURNAL OF INFLAMMATION RESEARCH. 2015;8:211-225
Translational utility of experimental autoimmune encephalomyelitis: recent developments.
Guerreiro-Cacais AO; Laaksonen H; Flytzani S; N'diaye M; Olsson T; Jagodic M
Review: NUTRITION AND CANCER. 2013;65(6):781-792
Epigenetics: A New Link Between Nutrition and Cancer
Supic G; Jagodic M; Magic Z
Editorial comment: NATURE GENETICS. 2013;45(2):116-118
Nurture your scientific curiosity early in your research career
Jagodic M; Stridh P; Gad AKB; Paine A; Udekwu KI; Sjoholm LK; Svensson M; Pan-Hammarstrom Q
Review: CURRENT OPINION IN IMMUNOLOGY. 2006;18(6):643-649
Genetics of autoimmune neuroinflammation
Olsson T; Jagodic M; Piehl F; Wallstrom E
Thesis / dissertation: 2004
The complex genetics of experimental autoimmune neuroinflammation
Jagodic, Maja
Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;60(1-2):39-51
Current gene-mapping strategies in experimental models of multiple sclerosis
Becanovic K; Jagodic M; Wallström E; Olsson T

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Professor, Klinisk neurovetenskap, Karolinska Institutet, 2021-

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Docent, Experimentell medicin, Karolinska Institutet, 2014
MEDICINE DOKTORSEXAMEN, Institutionen för medicin, Solna, Karolinska Institutet, 2004

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