Magdalini Lourda

Om mig
Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Om mig

Jag är Team leader vid Avdelningen för Klinisk mikrobiologi (Institutionen för laboratoriemedicin)

Artiklar

Article: JOURNAL OF INFECTIOUS DISEASES. 2024;:jiae036

Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19.

Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingström J; Geanon D; Parke Å; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarström Q; Lund-Johansen F; Strålin K; Björkström NK; Karolinska KI/K COVID-19 Study Group
Article: NATURE COMMUNICATIONS. 2024;15(1):1752

Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.

Kvedaraite E; Lourda M; Mouratidou N; Düking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Flodström Tullberg M; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjö-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Ideström M; Eulitz S; Arnell H; Mjösberg J; Henter J-I; Svensson M
Article: HAEMATOLOGICA. 2023;108(9):2422-2434

Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells.

Hagey DW; Kvedaraite E; Akber M; Görgens A; Javadi J; Von Bahr Greenwood T; Björklund C; Åkefeldt SO; Hannegård-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
Article: AIDS. 2023;37(7):1023-1033

Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment.

Svensson Akusjärvi S; Krishnan S; Ambikan AT; Mikaeloff F; Munusamy Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sönnerborg A; Neogi U
Article: CELL REPORTS MEDICINE. 2023;4(5):101038

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis.

Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Ideström M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjösberg J
Article: NATURE COMMUNICATIONS. 2023;14(1):1438

An integrated single cell and spatial transcriptomic map of human white adipose tissue.

Massier L; Jalkanen J; Elmastas M; Zhong J; Wang T; Nono Nankam PA; Frendo-Cumbo S; Bäckdahl J; Subramanian N; Sekine T; Kerr AG; Tseng BTP; Laurencikiene J; Buggert M; Lourda M; Kublickiene K; Bhalla N; Andersson A; Valsesia A; Astrup A; Blaak EE; Ståhl PL; Viguerie N; Langin D; Wolfrum C; Blüher M; Rydén M; Mejhert N
Article: IMMUNOBIOLOGY. 2023;228(2):152350

Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh.

Akhtar E; Mily A; Sarker P; Chanda BC; Haque F; Kuddusi RU; Haq MA; Lourda M; Brighenti S; Raqib R
Article: RESPIRATORY RESEARCH. 2023;24(1):62

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia.

Palma Medina LM; Babačić H; Dzidic M; Parke Å; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgård J; Moll K; Karolinska K. I./K. COVID-19 Study Group; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Gredmark-Russ S; Rooyackers O; Svensson M; Chambers BJ; Eriksson LI; Pernemalm M; Björkström NK; Aleman S; Ljunggren H-G; Klingström J; Strålin K; Norrby-Teglund A
Journal article: REVISTA CHILENA DE LITERATURA. 2023;(108):2422-2434

Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells

Hagey DW; Kvedaraite E; Akber M; Gorgens A; Javadi J; Greenwood TVB; Bjorklund C; Akefeldt SO; Hannegard-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940

Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.

Jädersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzén S; Bohlin A; Arnroth C; Erkers T; Seashore-Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Östling P; Schinazi RF; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis GZ; Höglund M; Henter J-I; Herold N
Article: CELL SYSTEMS. 2022;13(8):665-681.e4

Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.

Ambikan AT; Yang H; Krishnan S; Svensson Akusjärvi S; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sönnerborg A; Treutiger CJ; O'Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;198(4):721-728

Screening for neurodegeneration in Langerhans cell histiocytosis with neurofilament light in plasma.

Sveijer M; von Bahr Greenwood T; Jädersten M; Kvedaraite E; Zetterberg H; Blennow K; Lourda M; Gavhed D; Henter J-I
Journal article: HEMASPHERE. 2022;6:442-443

P543: TARGETING SAMHD1 WITH HYDROXYUREA IN FIRST‐LINE CYTARABINE‐BASED THERAPY OF NEWLY DIAGNOSED ACUTE MYELOID LEUKAEMIA: RESULTS FROM THE HEAT‐AML TRIAL

Jädersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzén S; Bohlin A; Arnroth C; Erkers T; Seashore‐Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Östling P; Schinazi R; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis G; Höglund M; Henter J; Herold N
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195

The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes.

Ljunggren H-G; Ask EH; Cornillet M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio A; Dzidic M; Filipovic I; Flodström-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingström J; Kokkinou E; Kvedaraite E; Lourda M; Mjösberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Karolinska KI/K COVID-19 Study Group; Eriksson LI; Aleman S; Malmberg K-J; Strålin K; Björkström NK
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510

COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations.

Cornillet M; Strunz B; Rooyackers O; Ponzetta A; Chen P; Muvva JR; Akber M; Buggert M; Chambers BJ; Dzidic M; Filipovic I; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingström J; Kokkinou E; Kvedaraite E; Lourda M; Mjösberg J; Maucourant C; Norrby-Teglund A; Parrot T; Perez-Potti A; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Karolinska KI/K COVID-19 Study Group; Eriksson LI; Aleman S; Strålin K; Ljunggren H-G; Björkström NK
Article: FRONTIERS IN PEDIATRICS. 2022;10:872859

Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions.

Mitchell J; Kvedaraite E; von Bahr Greenwood T; Lourda M; Henter J-I; Berzins SP; Kannourakis G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.

Lourda M; Dzidic M; Hertwig L; Bergsten H; Palma Medina LM; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki KT; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ; Karolinska KI/K COVID-19 Study Group
Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(14):149523

Discriminatory plasma biomarkers predict specific clinical phenotypes of necrotizing soft-tissue infections.

Palma Medina LM; Rath E; Jahagirdar S; Bruun T; Madsen MB; Strålin K; Unge C; Hansen MB; Arnell P; Nekludov M; Hyldegaard O; Lourda M; Santos VAMD; Saccenti E; Skrede S; Svensson M; Norrby-Teglund A
Article: ACTA PAEDIATRICA. 2021;110(4):1315-1321

Patients with both Langerhans cell histiocytosis and Crohn's disease highlight a common role of interleukin-23.

Kvedaraite E; Lourda M; Han H; Tesi B; Mitchell J; Ideström M; Mouratidou N; Rassidakis G; von Bahr Greenwood T; Cohen-Aubart F; Jädersten M; Åkefeldt SO; Svensson M; Kannourakis G; Bryceson YT; Haroche J; Henter J-I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity.

Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Hed Myrberg I; Lourda M; Dzidic M; Akber M; Klingström J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Ginhoux F; Björkström NK; Henter J-I; Svensson M; Karolinska KI/K COVID-19 Study Group
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306

SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.

Sandberg JT; Varnaitė R; Christ W; Chen P; Muvva JR; Maleki KT; García M; Dzidic M; Folkesson E; Skagerberg M; Ahlén G; Frelin L; Sällberg M; Eriksson LI; Rooyackers O; Sönnerborg A; Buggert M; Björkström NK; Aleman S; Strålin K; Klingström J; Ljunggren H-G; Blom K; Gredmark-Russ S; Karolinska COVID‐19 Study Group
Article: CELL. 2020;183(1):158-168.e14

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.

Sekine T; Perez-Potti A; Rivera-Ballesteros O; Strålin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgård J; Parrot T; Folkesson E; Karolinska COVID-19 Study Group; Rooyackers O; Eriksson LI; Henter J-I; Sönnerborg A; Allander T; Albert J; Nielsen M; Klingström J; Gredmark-Russ S; Björkström NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670

MAIT cell activation and dynamics associated with COVID-19 disease severity.

Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgård J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Björkström NK; Aleman S; Buggert M; Klingström J; Strålin K; Sandberg JK
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(163)

Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection.

Mily A; Kalsum S; Loreti MG; Rekha RS; Muvva JR; Lourda M; Brighenti S
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832

Natural killer cell immunotypes related to COVID-19 disease severity.

Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingström J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaëlsson J; Marquardt N; Hammer Q; Strålin K; Björkström NK; Karolinska COVID-19 Study Group
Article: CYTOKINE. 2020;126:154877

High levels of plasma interleukin-17A are associated with severe neurological sequelae in Langerhans cell histiocytosis.

Ismail MB; Åkefeldt SO; Lourda M; Gavhed D; Aricò M; Henter J-I; Delprat C; Valentin H
Article: METHODSX. 2020;7:100997

Comparison of three different ELISAs for the detection of recombinant, native and plasma IL-17A.

Ismail MB; Åkefeldt SO; Lourda M; Gavhed D; Gayet R; Aricò M; Henter J-I; Delprat C; Valentin H
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2020;9(12):e1224

Innate lymphoid cell composition associates with COVID-19 disease severity.

García M; Kokkinou E; Carrasco García A; Parrot T; Palma Medina LM; Maleki KT; Christ W; Varnaitė R; Filipovic I; Ljunggren H-G; Björkström NK; Folkesson E; Rooyackers O; Eriksson LI; Sönnerborg A; Aleman S; Strålin K; Gredmark-Russ S; Klingström J; Mjösberg J; Karolinska KI/K COVID‐19 Study Group
Article: NATURE COMMUNICATIONS. 2019;10(1):3841

Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.

Marquardt N; Kekäläinen E; Chen P; Lourda M; Wilson JN; Scharenberg M; Bergman P; Al-Ameri M; Hård J; Mold JE; Ljunggren H-G; Michaëlsson J
Journal article: PEDIATRIC BLOOD & CANCER. 2019;66 Suppl 1:e27548

Abstracts from the 34th Annual Meeting of the Histiocyte Society Lisbon, Portugal October 22-23, 2018.
Journal article: JOURNAL OF CROHNS & COLITIS. 2018;12(supplement_1):s119-s120

P054 Innate lymphoid cells in paediatric inflammatory bowel disease

Van Acker A; Kvedaraite E; Lourda M; Ideström M; Henter J-I; Svensson M; Mjösberg J
Journal article: PEDIATRIC BLOOD & CANCER. 2017;64 Suppl 2

Abstracts From the 33rd Annual Meeting of the Histiocyte Society Singapore October 3-4, 2017.
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):249-350

SSI 2017 44th Annual Meeting of the Scandinavian Society of Immunology Stockholm, Sweden 17–20 October 2017
Journal article: PEDIATRIC BLOOD & CANCER. 2016;63 Suppl 2:S10-S65

Abstracts From the 32nd Annual Meeting of the Histiocyte Society Dublin, Ireland October 17-19, 2016.
Article: GUT. 2016;65(10):1632-1641

Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD.

Kvedaraite E; Lourda M; Ideström M; Chen P; Olsson-Åkefeldt S; Forkel M; Gavhed D; Lindforss U; Mjösberg J; Henter J-I; Svensson M
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46 Suppl 1:1-1238

Abstracts of ICI 2016 International Congress of Immunology, 21-26 August 2016, Melbourne, Australia.
Article: ONCOIMMUNOLOGY. 2016;5(3):e1084463

The presence of CXCR4+ CD1a+ cells at onset of Langerhans cell histiocytosis is associated with a less favorable outcome.

Quispel WT; Stegehuis-Kamp JA; Blijleven L; Santos SJ; Lourda M; van den Bos C; van Halteren AGS; Egeler RM
Journal article: PEDIATRIC BLOOD & CANCER. 2015;62(S3):s121-s141

ABSTRACTS FROM THE 31st ANNUAL MEETING OF THE HISTIOCYTE SOCIETY ATHENS, GREECE SEPTEMBER 28–30, 2015
Journal article: PEDIATRIC BLOOD & CANCER. 2015;62 Suppl 1:S1-S18

Abstracts from the 30(th) Annual Meeting of the Histiocyte Society Toronto, Ontario, Canada October 28-30, 2014.
Journal article: PEDIATRIC BLOOD & CANCER. 2014;61(11):2129-2143

Histiocyte society 29th annual meeting abstracts Washington, DC USA
Article: CLINICAL IMMUNOLOGY. 2014;153(1):112-122

Detection of IL-17A-producing peripheral blood monocytes in Langerhans cell histiocytosis patients.

Lourda M; Olsson-Åkefeldt S; Gavhed D; Björnfot S; Clausen N; Hjalmars U; Sabel M; Tazi A; Aricò M; Delprat C; Henter J-I; Svensson M
Journal article: PEDIATRIC BLOOD & CANCER. 2013;60(9):E70-E84

Abstract
Article: PLOS ONE. 2013;8(3):e58122

Human herpesvirus 6A partially suppresses functional properties of DC without viral replication.

Gustafsson RKL; Engdahl EE; Hammarfjord O; Adikari SB; Lourda M; Klingström J; Svensson M; Fogdell-Hahn A
Article: CLINICAL CANCER RESEARCH. 2009;15(1):48-59

Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex.

Trougakos IP; Lourda M; Antonelou MH; Kletsas D; Gorgoulis VG; Papassideri IS; Zou Y; Margaritis LH; Boothman DA; Gonos ES
Article: BIOINORGANIC CHEMISTRY AND APPLICATIONS. 2008;2008:420578-6

Biological monitoring of hexavalent chromium and serum levels of the senescence biomarker apolipoprotein J/Clusterin in welders.

Alexopoulos EC; Cominos X; Trougakos IP; Lourda M; Gonos ES; Makropoulos V
Article: INTERNATIONAL JOURNAL OF CANCER. 2007;120(3):611-622

Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J.

Lourda M; Trougakos IP; Gonos ES
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2005;38(4):436-449

Differential effects of clusterin/apolipoprotein J on cellular growth and survival.

Trougakos IP; Lourda M; Agiostratidou G; Kletsas D; Gonos ES
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Alla övriga publikationer

Preprint: BIORXIV. 2023

Alpha-toxin elicited CX3CL1-release via ADAM10 in Staphylococcus aureus pneumonia impairs bactericidal function of human monocytes

Shambat SM; Chen P; Barilla RM; Huemer M; Snäll J; Welin A; Cohen TS; Takahashi V; Berry SB; Gómez-Mejia A; Schweizer TA; Cunoosamy DM; Cajander S; Lourda M; Özenci V; Maggio EM; Schüpbach RA; Strålin K; Zinkernagel AS; Norrby-Teglund A; Svensson M
Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(7):1306-1309.e4

Baricitinib Blocks Cytokine-Mediated Downregulation of PAD1 in Human Keratinocytes: A Possible Molecular Link to the Effects of JAK Inhibitors in Atopic Dermatitis.

Padhi A; Rekha RS; Benrejdal L; Grundeken ME; Lourda M; Ehrström M; Eyerich K; Páez IT; Johansson EK; Bradley M; Bergman P; Lysell J
Conference publication: PEDIATRIC BLOOD & CANCER. 2023;70:S20-S21

SCREENING FOR NEURODEGENERATION IN LCH WITH NEUROFILAMENT LIGHT IN PLASMA

Henter J-I; Sveijer M; Jadersten M; Kvedaraite E; Zetterberg H; Blennow K; Lourda M; Gavhed D; Greenwood TVB
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2022;97(6):E207-E210

Mutation in the TACI gene and autoimmune neutropenia: A case report.

Bergman P; Broliden P-A; Ratcliffe P; Lourda M; Flesch B; Höglund P; Palmblad J
Preprint: RESEARCH SQUARE. 2022

Monocyte driven system-level inflammatory and immunometabolic dysregulation during prolonged successful HIV-1 treatment

Akusjärvi SS; Krishnan S; Ambikan A; Mikaeloff F; Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sönnerborg A; Neogi U
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):248-254

Response to mitogen-activated protein kinase inhibition of neurodegeneration in Langerhans cell histiocytosis monitored by cerebrospinal fluid neurofilament light as a biomarker: a pilot study.

Henter J-I; Kvedaraite E; Martín Muñoz D; Cheng Munthe-Kaas M; Zeller B; Nystad TA; Björklund C; Donnér I; Lourda M; Zetterberg H; Blennow K; Herold N; Gavhed D; von Bahr Greenwood T
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S17

Plasma Signalling Factors in patients with Langerhans Cell Histiocytosis (Lch) Correlate with Relative Frequencies of Lch cells and T cells within Lesions

Mitchell J; Kvedaraite E; Greenwood TVB; Lourda M; Henter J-I; Berzins S; Kannourakis G
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S10

Response to Mapk Inhibition of Neurodegeneration in Lch Monitored by Csf Neurofilament Light as a Biomarker

Henter J-I; Kvedaraite E; Munoz DM; Munthe-Kaas MC; Zeller B; Nystad T; Bjorklund C; Donner I; Lourda M; Zetterberg H; Blennow K; Herold N; Gavhed D; Greenwood TVB
Preprint: MEDRXIV. 2021

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19

Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LP; Kvedaraite E; Chen P; Muvva J; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki K; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg J; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson L; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström N; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers B; the Karolinska KI/K COVID-19 Study Group
Preprint: SSRN ELECTRONIC JOURNAL. 2021

Multiomics Personalized Network Analyses Highlight Progressive Immune Disruption of Central Metabolism Associated with COVID-19 Severity

Ambikan AT; Yang H; Krishnan S; Svensson-Akusjärvi S; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sönnerborg A; Treutiger CJ; O’Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Corrigendum: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(164)

Erratum: Polarization of M1 and M2 Human Monocyte-Derived Cells and Analysis with Flow Cytometry upon Mycobacterium tuberculosis Infection.
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(1):115-119

High prevalence of peripheral lymphopenia in Langerhans cell histiocytosis.

Lourda M; Widesköld S; Kvedaraite E; Gavhed D; Akber M; von Bahr Greenwood T; Svensson M; Olsson-Åkefeldt S; Henter J-I
Preprint: MEDRXIV. 2020

Perturbations in the mononuclear phagocyte landscape associated with COVID-19 disease severity

Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingström J; Folkesson E; Muvva JR; Chen P; Brighenti S; Norrby-Teglund A; Eriksson L; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Ginhoux F; Björkström N; Henter J-I; Svensson M; Karolinska COVID-19 Study Group
Conference publication: PEDIATRIC BLOOD & CANCER. 2020;67:S17-S18

PERSISTENT LYMPHOPENIA IN LCH PATIENTS LIKELY RELATED TO CONSTANTLY HIGH LEVELS OF IL-7 AND IL-21

Lourda M; Wideskold S; Kvedaraite E; Gavhed D; Greenwood TVB; Svensson M; Olsson-Akefeldt S; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2019;66:S25-S26

ACTIVATION OF THE IL-23 SIGNALING PATHWAY IN LCH LESIONS

Lourda M; Kvedaraite E; Olsson-Akefeldt S; Holmstrom SB; Greenwood TVB; Svensson M; Henter J-I
Conference publication: JOURNAL OF CROHNS & COLITIS. 2018;12:S119-S120

Innate lymphoid cells in paediatric inflammatory bowel disease

Van Acker A; Kvedaraite E; Lourda M; Idestrom M; Henter J-I; Svensson M; Mjosberg J
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):316

Increased prevalence of lymphopenia in patients with Langerhans cell histiocytosis

Lourda M; Olsson-Akefeldt S; Gavhed S; Kvedaraite E; Gavhed D; Svensson M; Henter J-I
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):253

Stromal cell - innate immune cell interactions in inflammatory bowel disease patients

Kvedaraite E; Lourda M; Van Acker A; Jess DU; Gavhed D; Mjosberg J; Idestrom M; Henter J-I; Svensson M
Conference publication: PEDIATRIC BLOOD & CANCER. 2017;64:S21-S22

High Prevalence of Lymphopenia in Langerhans Cell Histiocytosis: Correlation with Early Onset and More Severe Disease

Lourda M; Olsson-Akefeldt S; Gavhed S; Kvedaraite E; Gavhed D; Svensson M; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2017;64:S20

When Langerhans Met Crohn: A Clinical Case Report and a First Three-Dimentional Reconstruction of Human Gut

Kvedaraite E; Jess DU; Gavhed D; Idestrom M; Svensson M; Lourda M; Henter J-I
Letter: BLOOD. 2016;128(9):1302-1305

Adsorptive depletion of blood monocytes reduces the levels of circulating interleukin-17A in Langerhans cell histiocytosis.

Lourda M; Olsson-Åkefeldt S; Gavhed D; Axdorph Nygell U; Berlin G; Laurencikas E; von Bahr Greenwood T; Svensson M; Henter J-I
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:1007-1008

In vitro neutralization of IL-17A sensitizes dendritic cells to vinblastine in Langerhans cell histiocytosis

Akefeldt OS; Ismail MB; Belot A; Lourda M; Valentin H; Maisse C; Salvatore G; Bissay N; Svensson M; Arico M; Henter J-I; Delprat C
Conference publication: PEDIATRIC BLOOD & CANCER. 2016;63:S24-S25

Adsorptive Depletion of Blood Monocytes Reduces the Levels of Circulating Interleukin-17A in Langerhans Cell Histiocytosis

Lourda M; Olsson-Akefeldt S; Gavhed D; Nygell UA; Berlin G; Laurencikas E; Greenwood TVB; Svensson M; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2015;62:S131-S132

INTERLEUKIN-17A AS A BIOMARKER IN NEURODEGENERATIVE LANGERHANS CELL HISTIOCYTOSIS

Lourda M; Olsson-Akefeldt S; Gavhed D; Greenwood TVB; Svensson M; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2015;62:S10

EXPLORATION OF THE IL-23/IL-17A AXIS IN LANGERHANS CELL HISTIOCYTOSIS

Kvedaraite E; Lourda M; Chen P; Gavhed D; Svensson M; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2014;61(11):2135

PRODUCTION BY BLOOD MONOCYTES IS TIGHTLY RELATED TO THE DEGREE OF ACTIVITY OF LANGERHANS CELL HISTIOCYTOSIS

Lourda M; Akefeldt SO; Gavhed D; Clausen N; Hjalmars U; Sabel M; Tazi A; Arico M; Delprat C; Svensson M; Henter J-I
Conference publication: PEDIATRIC BLOOD & CANCER. 2013;60(9):E79-E80

CIRCULATING CYTOKINE-PRODUCING CELLS IN LANGERHANS CELL HISTIOCYTOSIS

Lourda M; Akefeldt SO; Gavhed D; Svensson M; Henter J-I
Conference publication: FEBS JOURNAL. 2008;275:346

Clusterin binds to the cytoplasmic Ku70-Bax nexus and suppresses Bax activation and relocation to mitochondria

Trougakos IP; Lourda M; Antonelou MM; Kletsas D; Gorgoulis VG; Papassideri IS; Zou Y; Margaritis LH; Boothman DA; Gonos ES
Conference publication: FEBS JOURNAL. 2006;273:313

Implication of clusterin/apolipoprotein J in resistance acquisition of cancer cells to chemotherapy

Lourda M; Trougakos IP; Gonos ES
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Phenotypic and functional characterization of granulocytes in LCH

Swedish Childhood Cancer Fund

1 January 2021 - 31 December 2021

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