Lynn Butler
Senior Forskningsspecialist
E-postadress: lynn.butler@ki.se
Besöksadress: Anna Steckens gata 47, L7:04, 17164 Solna
Postadress: K1 Molekylär medicin och kirurgi, K1 MMK Klin kemi & koagulation, 171 76 Stockholm
Forskningsbeskrivning
- The primary focus of my research group is the study of endothelial cells that
line the inside of all blood vessels. These cells have many functions, such
as providing an anti-thrombotic surface to prevent blood clotting and
controlling leukocyte recruitment to tissue during inflammation. Our research
is based around the identification of genes that are highly specifically
expressed in endothelial cells (compared to other cell types) and the role of
these genes in vascular function. Through this work, we identify potential
plasma biomarker candidates for the clinical assessment of vascular health
and risk stratification, diagnosis and prognosis of diseases of the
cardiovascular system, such as venous and arterial thrombosis and COVID-19
complications.
Artiklar
- Article: BMC BIOLOGY. 2024;22(1):36
- Article: JOURNAL OF IMMUNOLOGY. 2024;212(1):117-129
- Article: NATURE COMMUNICATIONS. 2023;14(1):3280
- Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1181761
- Article: CELL REPORTS. 2022;40(2):111046
- Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2022;6(3):e12706
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:1008410
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(12):2990-3004
- Article: NATURE COMMUNICATIONS. 2021;12(1):5596
- Article: SCIENCE ADVANCES. 2021;7(31):eabh2169
- Article: SCIENTIFIC REPORTS. 2021;11(1):14015
- Article: BLOOD. 2021;137(10):1392-1405
- Article: CELL REPORTS. 2019;29(6):1690-1706.e4
- Article: CELLULAR AND MOLECULAR BIOENGINEERING. 2019;12(1):15-32
- Article: CYTOKINE. 2018;111:563-566
- Article: SCIENTIFIC REPORTS. 2018;8(1):14668
- Article: BLOOD. 2016;128(23):e59-e66
- Article: CELL SYSTEMS. 2016;3(3):287-301.e3
- Article: NATURE COMMUNICATIONS. 2016;7:12616
- Article: THROMBOSIS RESEARCH. 2016;141:S4-S7
- Article: METHODS IN MOLECULAR BIOLOGY. 2016;1430:231-248
- Article: OPEN FORUM INFECTIOUS DISEASES. 2015;2(4):ofv155
- Article: JOURNAL OF GENERAL VIROLOGY. 2015;96(12):3598-3612
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(4):1031-1043.e6
- Article: THROMBOSIS AND HAEMOSTASIS. 2014;112(2):332-341
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2014;25(8):1669-1678
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(4):801-809
- Article: BASIC RESEARCH IN CARDIOLOGY. 2014;109(2):401
- Article: HERPESVIRIDAE. 2013;4(1):3
- Article: JOURNAL OF VIROLOGICAL METHODS. 2013;193(1):251-259
- Article: IMMUNOBIOLOGY. 2013;218(8):1034-1040
- Article: JOURNAL OF VIROLOGY. 2013;87(11):6530-6535
- Article: JOURNAL OF IMMUNOLOGY. 2013;190(2):678-688
- Article: THROMBOSIS AND HAEMOSTASIS. 2012;108(4):719-729
- Article: JOURNAL OF VIROLOGY. 2012;86(13):7158-7166
- Article: JOURNAL OF GENERAL VIROLOGY. 2011;92(Pt 10):2394-2398
- Article: JOURNAL OF VIROLOGY. 2011;85(14):7321-7332
- Article: EXPERIMENTAL CELL RESEARCH. 2011;317(3):276-292
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(48):37641-37649
- Article: EXPERIMENTAL CELL RESEARCH. 2009;315(19):3433-3441
- Article: METHODS IN MOLECULAR BIOLOGY. 2009;467:211-228
- Article: CRITICAL CARE MEDICINE. 2008;36(5):1536-1542
- Article: CELLULAR IMMUNOLOGY. 2008;251(1):56-61
- Article: THROMBOSIS AND HAEMOSTASIS. 2007;97(5):814-821
- Article: METHODS IN MOLECULAR BIOLOGY. 2007;370:37-54
- Article: BIORHEOLOGY. 2006;43(1):71-82
- Article: EXPERIMENTAL CELL RESEARCH. 2005;310(1):22-32
- Visa fler
Alla övriga publikationer
- Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):7752
- Preprint: BIORXIV. 2023
- Preprint: BIORXIV. 2023
- Preprint: BIORXIV. 2023
- Preprint: BIORXIV. 2022
- Book chapter: COMPUTATIONAL METHODS IN SYSTEMS BIOLOGY: LECTURE NOTES IN COMPUTER SCIENCE (INCLUDING SUBSERIES LECTURE NOTES IN ARTIFICIAL INTELLIGENCE AND LECTURE NOTES IN BIOINFORMATICS). 2021;p. 108-121
- Preprint: SSRN ELECTRONIC JOURNAL. 2019
- Review: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2017;43(8):814-826
- Review: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37(1):13-20
- Review: ANNALS OF TRANSLATIONAL MEDICINE. 2015;3(17):247
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:954
- Review: JOURNAL OF LEUKOCYTE BIOLOGY. 2012;91(3):385-400
- Conference publication: NEURO-ONCOLOGY. 2012;14:52