Lynn Butler
Senior Research Specialist
E-mail: lynn.butler@ki.se
Visiting address: Anna Steckens gata 47, L7:04, 17164 Solna
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Klin kemi & koagulation, 171 76 Stockholm
Research
- The primary focus of my research group is the study of endothelial cells that
line the inside of all blood vessels. These cells have many functions, such
as providing an anti-thrombotic surface to prevent blood clotting and
controlling leukocyte recruitment to tissue during inflammation. Our research
is based around the identification of genes that are highly specifically
expressed in endothelial cells (compared to other cell types) and the role of
these genes in vascular function. Through this work, we identify potential
plasma biomarker candidates for the clinical assessment of vascular health
and risk stratification, diagnosis and prognosis of diseases of the
cardiovascular system, such as venous and arterial thrombosis and COVID-19
complications.
Articles
- Article: BLOOD. 2025;146(5):628-637Mohapatra AK; Vlieg AVH; Kleber ME; Martinez-Perez A; Le N-Q; Hindberg KD; Dusart P; Germain M; Thibord F; Deleuze J-F; Delgado GE; Goumidi L; Suchon P; Saut N; Souto J-C; Butler LM; Soria J-M; Hansen J-B; Maerz W; Rosendaal FR; Castoldi E; Peiretti F; Sabater-Lleal M; Tregouet D-A; Morange P-E
- Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2025;222(7):e20250049Nickel KF; Jamsa A; Konrath S; Papareddy P; Butler LM; Stavrou EX; Frye M; Gelderblom M; Nieswandt B; Hammerschmidt S; Herwald H; Renne T
- Journal article: GENOME BIOLOGY. 2025;26(1):152Shi M; Mear L; Karlsson M; Alvez MB; Digre A; Schutten R; Katona B; Vuu J; Lindstrom E; Hikmet F; Jin H; Yuan M; Li X; Yang H; Song X; Sjostedt E; Edfors F; Oksvold P; von Feilitzen K; Zwahlen M; Forsberg M; Johansson F; Mulder J; Hokfelt T; Luo Y; Butler L; Zhong W; Mardinoglu A; Sivertsson A; Ponten F; Fagerberg L; Lindskog C; Uhlen M; Zhang C
- Article: BMC BIOLOGY. 2024;22(1):36Oling S; Struck E; Noreen-Thorsen M; Zwahlen M; von Feilitzen K; Odeberg J; Ponten F; Lindskog C; Uhlen M; Dusart P; Butler LM
- Article: JOURNAL OF IMMUNOLOGY. 2024;212(1):117-129Struck EC; Belova T; Hsieh P-H; Odeberg JO; Kuijjer ML; Dusart PJ; Butler LM
- Article: NATURE COMMUNICATIONS. 2023;14(1):3280Iglesias MJ; Sanchez-Rivera L; Ibrahim-Kosta M; Naudin C; Munsch G; Goumidi L; Farm M; Smith PM; Thibord F; Kral-Pointner JB; Hong M-G; Suchon P; Germain M; Schrottmaier W; Dusart P; Boland A; Kotol D; Edfors F; Koprulu M; Pietzner M; Langenberg C; Damrauer SM; Johnson AD; Klarin DM; Smith NL; Smadja DM; Holmstrom M; Magnusson M; Silveira A; Uhlen M; Renne T; Martinez-Perez A; Emmerich J; Deleuze J-F; Antovic J; Soria Fernandez JM; Assinger A; Schwenk JM; Souto Andres JC; Morange P-E; Butler LM; Tregouet D-A; Odeberg J
- Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1181761Englert H; Goebel J; Khong D; Omidi M; Wolska N; Konrath S; Frye M; Mailer RK; Beerens M; Gerwers JC; Preston RJS; Odeberg J; Butler LM; Maas C; Stavrou EX; Fuchs TA; Renne T
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:1008410Konrath S; Mailer RK; Beerens M; Englert H; Frye M; Kuta P; Preston RJS; Maas C; Butler LM; Roest M; de Laat B; Renne T
- Article: CELL REPORTS. 2022;40(2):111046Norreen-Thorsen M; Struck EC; Oling S; Zwahlen M; Von Feilitzen K; Odeberg J; Lindskog C; Ponten F; Uhlen M; Dusart PJ; Butler LM
- Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2022;6(3):e12706Edfors F; Iglesias MJ; Butler LM; Odeberg J
- Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(12):2990-3004Iglesias MJ; Kruse LD; Sanchez-Rivera L; Enge L; Dusart P; Hong M-G; Uhlen M; Renne T; Schwenk JM; Bergstrom G; Odeberg J; Butler LM
- Article: NATURE COMMUNICATIONS. 2021;12(1):5596Heestermans M; Naudin C; Mailer RK; Konrath S; Klaetschke K; Jamsa A; Frye M; Deppermann C; Pula G; Kuta P; Friese MA; Gelderblom M; Sickmann A; Preston RJS; Nofer J-R; Rose-John S; Butler LM; Salomon O; Stavrou EX; Renne T
- Article: SCIENCE ADVANCES. 2021;7(31):eabh2169Karlsson M; Zhang C; Mear L; Zhong W; Digre A; Katona B; Sjoestedt E; Butler L; Odeberg J; Dusart P; Edfors F; Oksvold P; von Feilitzen K; Zwahlen M; Arif M; Altay O; Li X; Ozcan M; Mardonoglu A; Fagerberg L; Mulder J; Luo Y; Ponten F; Uhlen M; Lindskog C
- Article: SCIENTIFIC REPORTS. 2021;11(1):14015Razzaq M; Iglesias MJ; Ibrahim-Kosta M; Goumidi L; Soukarieh O; Proust C; Roux M; Suchon P; Boland A; Daiain D; Olaso R; Havervall S; Thalin C; Butler L; Deleuze J-F; Odeberg J; Morange P-E; Tregouet D-A
- Article: BLOOD. 2021;137(10):1392-1405Mailer RK; Allende M; Heestermans M; Schweizer M; Deppermann C; Frye M; Pula G; Odeberg J; Gelderblom M; Rose-John S; Sickmann A; Blankenberg S; Huber TB; Kubisch C; Maas C; Gambaryan S; Firsov D; Stavrou EX; Butler LM; Renne T
- Article: CELL REPORTS. 2019;29(6):1690-1706.e4Dusart P; Hallstrom BM; Renne T; Odeberg J; Uhlen M; Butler LM
- Article: CELLULAR AND MOLECULAR BIOENGINEERING. 2019;12(1):15-32Ahmed M; Gustafsson B; Aldi S; Dusart P; Egri G; Butler LM; Bone D; Dahne L; Hedin U; Caidahl K
- Article: CYTOKINE. 2018;111:563-566Gustafsson KLR; Renne T; Soderberg-Naucler C; Butler LM
- Article: SCIENTIFIC REPORTS. 2018;8(1):14668Dusart P; Fagerberg L; Perisic L; Civelek M; Struck E; Hedin U; Uhlen M; Tregouet D-A; Renne T; Odeberg J; Butler LM
- Article: BLOOD. 2016;128(23):e59-e66Bruzelius M; Iglesias MJ; Hong M-G; Sanchez-Rivera L; Gyorgy B; Carlos Souto J; Franberg M; Fredolini C; Strawbridge RJ; Holmstrom M; Hamsten A; Uhlen M; Silveira A; Manuel Soria J; Smadja DM; Butler LM; Schwenk JM; Morange P-E; Tregouet D-A; Odeberg J
- Article: CELL SYSTEMS. 2016;3(3):287-301.e3Butler LM; Hallstrom BM; Fagerberg L; Ponten F; Uhlen M; Renne T; Odeberg J
- Article: NATURE COMMUNICATIONS. 2016;7:12616Labberton L; Kenne E; Long AT; Nickel KF; Di Gennaro A; Rigg RA; Hernandez JS; Butler L; Maas C; Stavrou EX; Renne T
- Article: THROMBOSIS RESEARCH. 2016;141:S4-S7Nickel KF; Labberton L; Long AT; Langer F; Fuchs TA; Stavrou EX; Butler LM; Renne T
- Article: METHODS IN MOLECULAR BIOLOGY. 2016;1430:231-248Butler LM; McGettrick HM; Nash GB
- Article: OPEN FORUM INFECTIOUS DISEASES. 2015;2(4):ofv155Yaiw K-C; Mohammad A-A; Costa H; Taher C; Badrnya S; Assinger A; Wilhelmi V; Ananthaseshan S; Estekizadeh A; Davoudi B; Ovchinnikova O; Shlyakhto E; Rafnsson A; Khan Z; Butler L; Rahbar A; Pernow J; Söderberg-Nauclér C
- Article: JOURNAL OF GENERAL VIROLOGY. 2015;96(12):3598-3612Gustafsson RKL; Jeffery HC; Yaiw K-C; Wilhelmi V; Kostopoulou ON; Davoudi B; Rahbar A; Benard M; Renne T; Soderberg-Naucler C; Butler LM
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(4):1031-1043.e6Sala-Cunill A; Bjoerkqvist J; Senter R; Guilarte M; Cardona V; Labrador M; Nickel KF; Butler L; Luengo O; Kumar P; Labberton L; Long A; Di Gennaro A; Kenne E; Jaemsae A; Krieger T; Schlueter H; Fuchs T; Flohr S; Hassiepen U; Cumin F; McCrae K; Maas C; Stavrou E; Renne T
- Article: THROMBOSIS AND HAEMOSTASIS. 2014;112(2):332-341Assinger A; Wang Y; Butler LM; Hansson GK; Yan Z-Q; Soderberg-Naucler C; Ketelhuth DFJ
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2014;25(8):1669-1678Butler LM; Dzabic M; Bakker F; Davoudi B; Jeffery H; Religa P; Bojakowski K; Yaiw K-C; Rahbar A; Soederberg-Naucler C
- Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014;34(4):801-809Assinger A; Kral JB; Yaiw KC; Schrottmaier WC; Kurzejamska E; Wang Y; Mohammad A-A; Religa P; Rahbar A; Schabbauer G; Butler LM; Soderberg-Naucler C
- Article: BASIC RESEARCH IN CARDIOLOGY. 2014;109(2):401Yaiw K-C; Mohammad A-A; Taher C; Wilhelmi V; Davoudi B; Straat K; Assinger A; Ovchinnikova O; Shlyakhto E; Rahbar A; Koutonguk O; Religa P; Butler L; Khan Z; Streblow D; Pernow J; Soderberg-Naucler C
- Article: HERPESVIRIDAE. 2013;4(1):3Yaiw K-C; Ovchinnikova O; Taher C; Mohammad A-A; Davoudi B; Shlyakhto E; Rotar O; Konradi A; Wilhelmi V; Rahbar A; Butler L; Assinger A; Söderberg-Nauclér C
- Article: JOURNAL OF VIROLOGICAL METHODS. 2013;193(1):251-259Jeffery HC; Wheat RL; Blackbourn DJ; Nash GB; Butler LM
- Article: IMMUNOBIOLOGY. 2013;218(8):1034-1040Fornara O; Odeberg J; Khan Z; Stragliotto G; Peredo I; Butler L; Soderberg-Naucler C
- Article: JOURNAL OF VIROLOGY. 2013;87(11):6530-6535Jeffery HC; Soderberg-Naucler C; Butler LM
- Article: JOURNAL OF IMMUNOLOGY. 2013;190(2):678-688Xu N; Meisgen F; Butler LM; Han G; Wang X-J; Soderberg-Naucler C; Stahle M; Pivarcsi A; Sonkoly E
- Article: THROMBOSIS AND HAEMOSTASIS. 2012;108(4):719-729Platelets directly enhance neutrophil transmigration in response to oxidised low-density lipoproteinBadrnya S; Butler LM; Soderberg-Naucler C; Volf I; Assinger A
- Article: JOURNAL OF VIROLOGY. 2012;86(13):7158-7166Butler LM; Jeffery HC; Wheat RL; Long HM; Rae PC; Nash GB; Blackbourn DJ
- Article: JOURNAL OF GENERAL VIROLOGY. 2011;92(Pt 10):2394-2398Mutocheluh M; Hindle L; Aresté C; Chanas SA; Butler LM; Lowry K; Shah K; Evans DJ; Blackbourn DJ
- Article: JOURNAL OF VIROLOGY. 2011;85(14):7321-7332Butler LM; Jeffery HC; Wheat RL; Rae PC; Townsend K; Alkharsah KR; Schulz TF; Nash GB; Blackbourn DJ
- Article: EXPERIMENTAL CELL RESEARCH. 2011;317(3):276-292Burton VJ; Butler LM; McGettrick HM; Stone PC; Jeffery HC; Savage CO; Rainger GE; Nash GB
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(48):37641-37649Durrington HJ; Upton PD; Hoer S; Boname J; Dunmore BJ; Yang J; Crilley TK; Butler LM; Blackbourn DJ; Nash GB; Lehner PJ; Morrell NW
- Article: EXPERIMENTAL CELL RESEARCH. 2009;315(19):3433-3441Butler LM; Rainger GE; Nash GB
- Article: METHODS IN MOLECULAR BIOLOGY. 2009;467:211-228Butler LM; McGettrick HM; Nash GB
- Article: CRITICAL CARE MEDICINE. 2008;36(5):1536-1542Matharu NM; Butler LM; Rainger GE; Gosling P; Vohra RK; Nash GB
- Article: CELLULAR IMMUNOLOGY. 2008;251(1):56-61Butler LM; Khan S; Ed Rainger G; Nash GB
- Article: THROMBOSIS AND HAEMOSTASIS. 2007;97(5):814-821Butler LM; Metson-Scott T; Felix J; Abhyankar A; Rainger GE; Farndale RW; Watson SP; Nash GB
- Article: METHODS IN MOLECULAR BIOLOGY. 2007;370:37-54McGettrick HM; Butler LM; Nash GB
- Article: BIORHEOLOGY. 2006;43(1):71-82Chakravorty SJ; McGettrick HM; Butler LM; Buckley CD; Rainger GE; Nash GB
- Article: EXPERIMENTAL CELL RESEARCH. 2005;310(1):22-32Butler LM; Rainger GE; Rahman M; Nash GB
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All other publications
- Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):7752Iglesias MJ; Sanchez-Rivera L; Ibrahim-Kosta M; Naudin C; Munsch G; Goumidi L; Farm M; Smith PM; Thibord F; Kral-Pointner JB; Hong M-G; Suchon P; Germain M; Schrottmaier W; Dusart P; Boland A; Kotol D; Edfors F; Koprulu M; Pietzner M; Langenberg C; Damrauer SM; Johnson AD; Klarin DM; Smith NL; Smadja DM; Holmström M; Magnusson M; Silveira A; Uhlén M; Renné T; Martinez-Perez A; Emmerich J; Deleuze J-F; Antovic J; Soria Fernandez JM; Assinger A; Schwenk JM; Souto Andres JC; Morange P-E; Butler LM; Trégouët D-A; Odeberg J
- Preprint: BIORXIV. 2023Struck EC; Belova T; Hsieh P; Odeberg J; Kuijjer ML; Dusart P; Butler LM
- Preprint: BIORXIV. 2023Öling S; Struck E; Thorsen MN; Zwahlen M; Feilitzen V; Odeberg J; Pontén F; Lindskog C; Uhlén M; Dusart P; Butler LM
- Preprint: BIORXIV. 2023Dusart P; Öling S; Struck E; Norreen-Thorsen M; Zwahlen M; von Feilitzen K; Oksvold P; Bosic M; Iglesias MJ; Renne T; Odeberg J; Pontén F; Lindskog C; Uhlén M; Butler LM
- Preprint: BIORXIV. 2022Karlsson M; Álvez MB; Shi M; Méar L; Schutten R; Hikmet F; Digre A; Katona B; Vuu J; Bosic M; Sjöstedt E; Edfors F; Oksvold P; von Feilitzen K; Zwahlen M; Forsberg M; Johansson F; Mulder J; Hökfelt T; Luo Y; Butler L; Zhong W; Mardinoglu A; Sivertsson Å; Ponten F; Zhang C; Lindskog C; Fagerberg L; Uhlén M
- Preprint: MEDRXIV. 2022Sanchez-Rivera L; Iglesias MJ; Ibrahim-Kosta M; Kral-Pointner JB; Havervall S; Goumidi L; Farm M; Munsch G; Germain M; Smith P; Hong M-G; Suchon P; Naudin C; Boland A; Smadja D; Holmström M; Magnusson M; Silveira A; Uhlén M; Renné T; Martinez-Perez A; Emmerich J; Deleuze J-F; Antovic J; Assinger A; Fernandez JMS; Thålin C; Schwenk J; Andres JCS; Morange P-E; Butler LM; Trégouët D-A; Odeberg J
- Preprint: MEDRXIV. 2021Identification of endothelial-derived proteins in plasma associated with cardiovascular risk factorsIglesias MJ; Kruse LD; Sanchez-Rivera L; Enge L; Dusart P; Hong MG; Uhlén M; Renné T; Schwenk JM; Bergstrom G; Odeberg J; Butler LM
- Book chapter: LECTURE NOTES IN COMPUTER SCIENCE. 2021;p. 108-121Razzaq M; Goumidi L; Iglesias M-J; Muns G; Bruzelius M; Ibrahim-Kosta M; Butler L; Odeberg J; Morange P-E; Tregouet DA
- Preprint: MEDRXIV. 2020Razzaq M; Iglesias MJ; Ibrahim-Kosta M; Goumidi L; Soukarieh O; Proust C; Roux M; Suchon P; Boland A; Daiain D; Olaso R; Butler L; Deleuze J-F; Odeberg J; Morange P-E; Trégouët D-A
- Preprint: BIORXIV. 2019Dusart P; Hallström B; Renne T; Odeberg J; Uhlén M; Butler L
- Preprint: SSRN ELECTRONIC JOURNAL. 2019Dusart P; Hallström BM; Renne T; Odeberg J; Uhlen M; Butler L
- Review: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2017;43(8):814-826Naudin C; Burillo E; Blankenberg S; Butler L; Renne T
- Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2017;37(1):13-20Nickel KF; Long AT; Fuchs TA; Butler LM; Renne T
- Review: ANNALS OF TRANSLATIONAL MEDICINE. 2015;3(17):247Worm M; Koehler EC; Panda R; Long A; Butler LM; Stavrou EX; Nickel KF; Fuchs TA; Renne T
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:954Bruzelius M; Iglesias MJ; Hong M-G; Tregouet DA; Souto JC; Holmstrom M; Franberg M; Strawbridge RJ; Sabater-Lleal M; Sennblad B; Silveira A; Soria JM; Morange PE; Butler L; Schwenk JM; Hamsten A; Odeberg J
- Conference publication: NEURO-ONCOLOGY. 2012;14:52Fornara O; Mirza S; Khan Z; Odeberg J; Stragliotto G; Butler L; Soderberg-Naucler C
- Review: JOURNAL OF LEUKOCYTE BIOLOGY. 2012;91(3):385-400McGettrick HM; Butler LM; Buckley CD; Rainger GE; Nash GB