Ljubica Matic
Om mig
Ljubica Matic är docent i molekylär medicin och senior forskare vid Kärlkirurgi vid Karolinska Institutet. Hon tog sin MSc-examen i molekylärbiologi från Belgrads universitet, Serbien och en doktorsexamen i medicinsk biokemi från Karolinska Institutet 2012. Sedan 2019 är hon gruppledare för Translationell Vaskulär Medicin vid Center for Molecular Medicine, KI dedikerad till translationell forskning om nya terapeutiska och diagnostiska mål för hantering av kardiovaskulär sjukdom, speciellt ateroskleros och restenoskomplikationer. Hennes arbete har genom åren utmärkts med anslag och utmärkelser från Vetenskapsrådet, Hjärt-Lungfonden, Svenska Sällskapet för Medicinsk Forskning, KI Faculty anslag, American Heart Association (Daniel Steinberg Early Career Investigator Award 2023) och Kungliga Vetenskapsakademien (Sven och Ebba Hagbergs pris 2019). Hon är PI för flera pågående EU Horizon-projekt och expertgranskare för Danish Cardiovascular Academy, French National Research Agency (ANR), Rumanian National Research Council, Polish National Research Council, Austrian National Science Fund, Swiss National Science Foundation, Dutch Innovative Research Incentives Scheme (VIDI), Dutch Heart Foundation, UK National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs). Ljubica Matic har cirka 100 publikationer med över 4 500 citeringar och h-index 34.
Forskningsbeskrivning
Matic group (https://linktr.ee/ljubicamatic) använder innovativa, integrerade multi-omics in silico-pipelines för utforskning av Biobank of Karolinska Endarterectomy (BiKE, est 2002, över 1800 patienter) för att identifiera glatta muskelceller relaterade mål som står i direkt orsakssamband till mänsklig kärlsjukdom. Målupptäckt följs av fenotypning, utmaning och proof-of-concept interventionsstudier i möss vaskulära skador och sjukdomsmodeller, såväl som in vitro-studier med primära mänskliga glatta muskelceller. Med detta multidisciplinära tillvägagångssätt är Ljubica Matics uppdrag att skapa en kraftfull plattform för extrapolering av grundforskningsresultat till de olika områdena av klinisk hjärt-kärlsjukdom, vilket kan leda till accelererad utveckling från målupptäckt till patientbehandling.
Undervisning
Sedan 2004 har Ljubica Matic kontinuerligt ägnat 20 % av sin tid åt pedagogiskt arbete som föreläsare, handledare och kursledare för doktorander på hjärt- och kärlprogrammet och studenter på medicin- och biomedicinprogrammen vid KI. Sedan 2013 är hon föreståndare för doktorandkursen i Vaskulär Cellbiologi, inom Kardiovaskulära Programmet, KI. Sedan 2021 är hon även co-direktor för elektiv spår i Cirkulation, Metabolism och Endokrinologi inom KI's MSc Global Biomedicine-programmet. Hon har också organiserat internationella doktorandkurser inom ramen för EU Horizon Marie Sklodowska Curie ITN-projekt.
Artiklar
- Article: EUROPEAN HEART JOURNAL. 2024;:ehae768
- Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2024;81(1):331
- Article: ANGIOGENESIS. 2024;27(3):461-474
- Journal article: ATHEROSCLEROSIS. 2023;379:s53
- Journal article: ATHEROSCLEROSIS. 2023;379:s23
- Journal article: ATHEROSCLEROSIS. 2023;379:s162
- Journal article: ATHEROSCLEROSIS. 2023;379:s180
- Article: CARDIOVASCULAR RESEARCH (CVR). 2023;119(7):1524-1536
- Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
- Article: VASCULAR PHARMACOLOGY. 2023;150:107167
- Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2023;65(6):778-786
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2023;43
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2023;43
- Article: CIRCULATION RESEARCH. 2023;132(9):1144-1161
- Article: ATHEROSCLEROSIS. 2023;371:41-53
- Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2023;152:106364
- Journal article: JVS - VASCULAR SCIENCE. 2023;4:100142
- Article: JVS - VASCULAR SCIENCE. 2023;4:100111
- Article: CELLS. 2022;11(20):3279
- Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2022;134:105403
- Journal article: ATHEROSCLEROSIS. 2022;355:24
- Article: ISCIENCE. 2022;25(5):104219
- Article: ATHEROSCLEROSIS. 2022;348:8-15
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42(5):659-676
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42:a217
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42:a105
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42:a420
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42:a419
- Article: CARDIOVASCULAR RESEARCH (CVR). 2022;118(5):1232-1246
- Article: STROKE. 2022;53(3):e79-e84
- Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2022;12(2):e682
- Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561
- Journal article: JVS - VASCULAR SCIENCE. 2022;3:413
- Article: CARDIOVASCULAR RESEARCH (CVR). 2021;117(14):2767-2780
- Journal article: CIRCULATION. 2021;144(Suppl_1):a14023
- Article: CIRCULATION. 2021;144(19):1567-1583
- Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2021;62(5):716-726
- Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.3405
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41
- Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2021;11(6):e458
- Article: CELLS. 2021;10(6):1276
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(5):1738-1750
- Article: VASCULAR MEDICINE. 2021;26(1):3-10
- Journal article: CIRCULATION. 2021;144(19):1567-1583
- Article: JVS - VASCULAR SCIENCE. 2021;2:260-273
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2021;8:655869
- Article: JOURNAL OF INTERNAL MEDICINE. 2021;289(1):53-68
- Journal article: ATHEROSCLEROSIS. 2020;315:e22-e23
- Article: JOURNAL OF INFECTIOUS DISEASES. 2020;222(12):2041-2051
- Article: NATURE METABOLISM. 2020;2(10):1135-1148
- Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2020;235(10):7370-7382
- Article: CELLS. 2020;9(10):E2164-2164
- Article: CIRCULATION RESEARCH. 2020;127(7):911-927
- Article: CELLS. 2020;9(4):E1009-1009
- Journal article: INVESTIGATIVE UROLOGY. 2020;203:e422-e423
- Article: CELLS. 2020;9(3):E684-684
- Article: CIRCULATION RESEARCH. 2020;126(5):571-585
- Journal article: EJVES SHORT REPORTS. 2020;48:52
- Journal article: EJVES SHORT REPORTS. 2020;48:47-48
- Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:619079
- Article: JVS - VASCULAR SCIENCE. 2020;1:166-167
- Article: JVS - VASCULAR SCIENCE. 2020;1:13-27
- Article: ATHEROSCLEROSIS. 2020;292:215-223
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2020;40:250-251
- Article: PLOS GENETICS. 2020;16(1):e1008538
- Journal article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2019;58(6):e469-e470
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2019;317(6):C1128-C1142
- Article: ATHEROSCLEROSIS. 2019;288:175-185
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(33):16410-16419
- Article: CIRCULATION. 2019;139(21):2466-2482
- Article: ATHEROSCLEROSIS. 2019;283:127-136
- Article: CIRCULATION. 2019;139(10):1320-1334
- Article: EUROPEAN HEART JOURNAL. 2019;40(4):372-382
- Article: NATURE METABOLISM. 2019;1(1):98-110
- Article: DIABETOLOGY AND METABOLIC SYNDROME. 2019;11:32
- Article: PLOS ONE. 2019;14(8):e0221477
- Article: CARDIOVASCULAR RESEARCH (CVR). 2019;115(1):230-242
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2018;315(6):C873-C884
- Article: PLOS GENETICS. 2018;14(11):e1007755
- Article: SCIENTIFIC REPORTS. 2018;8(1):14668
- Article: MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28
- Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2018;11(9):e002115
- Article: SCIENTIFIC REPORTS. 2018;8(1):13025
- Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy563.p3200
- Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy565.p2625
- Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):464-480
- Article: EUROPEAN HEART JOURNAL. 2018;39(24):2301-2310
- Article: MOLECULAR THERAPY. 2018;26(4):1040-1055
- Journal article: THE FASEB JOURNAL. 2018;32(S1):lb283
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2018;38(1):49-63
- Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444
- Journal article: EUROPEAN HEART JOURNAL. 2017;38(suppl_1):ehx493.p4918
- Article: PLOS GENETICS. 2017;13(5):e1006750
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37(suppl_1)
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(4):1546-1560
- Article: CIRCULATION RESEARCH. 2017;120(4):633-644
- Article: CARDIOVASCULAR RESEARCH (CVR). 2017;113(1):30-39
- Article: NATURE MEDICINE. 2016;22(10):1140-1150
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(9):1947-1961
- Article: NATURE. 2016;536(7614):86-90
- Article: NATURE COMMUNICATIONS. 2016;7:12092
- Article: SCIENCE ADVANCES. 2016;2(7):e1600224
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(suppl_1)
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(5):972-983
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(5):942-951
- Article: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):293-308
- Article: CIRCULATION RESEARCH. 2016;118(2):230-240
- Article: GENOMICS DATA. 2015;5:36-37
- Article: CIRCULATION RESEARCH. 2015;117(3):266-278
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2015;35(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2015;35(suppl_1)
- Article: PLOS GENETICS. 2015;11(5):e1005155
- Article: PLOS ONE. 2015;10(3):e0122067
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(suppl_1)
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(3):1083-1097
- Article: PLOS GENETICS. 2014;10(3):e1004263
- Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(10):2432-2443
- Journal article: EUROPEAN HEART JOURNAL. 2013;34(suppl_1):p394
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(suppl_1)
- Journal article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(suppl_1)
- Article: KIDNEY INTERNATIONAL. 2012;82(10):1071-1083
- Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2007;18(3):689-697
- Article: ACTA HAEMATOLOGICA. 2005;113(3):175-180
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Alla övriga publikationer
- Editorial comment: CARDIOVASCULAR RESEARCH (CVR). 2024;120(8):811-813
- Editorial comment: ATHEROSCLEROSIS. 2023;387:117365
- Conference publication: ATHEROSCLEROSIS. 2023;379:s5
- Conference publication: ATHEROSCLEROSIS. 2023;379:s18
- Editorial comment: CARDIOVASCULAR RESEARCH (CVR). 2023;119(5):1100-1102
- Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S129-S130
- Preprint: RESEARCH SQUARE. 2022
- Conference publication: ATHEROSCLEROSIS. 2022;355:10
- Preprint: BIORXIV. 2022
- Conference publication: JOURNAL OF VASCULAR SURGERY. 2022;75(6):E70-E71
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42:a218
- Conference publication: ATHEROSCLEROSIS. 2022;355:E93
- Conference publication: ATHEROSCLEROSIS. 2022;355:E54-E55
- Preprint: SSRN ELECTRONIC JOURNAL. 2022
- Conference publication: ATHEROSCLEROSIS. 2021;331:E61
- Conference publication: ATHEROSCLEROSIS. 2021;331:E64-E65
- Conference publication: ATHEROSCLEROSIS. 2021;331:E12-E13
- Conference publication: ATHEROSCLEROSIS. 2021;331:E92
- Conference publication: ATHEROSCLEROSIS. 2021;331:E31
- Conference publication: ATHEROSCLEROSIS. 2021;331:E93
- Conference publication: ATHEROSCLEROSIS. 2021;331:E4
- Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3405
- Conference publication: ATHEROSCLEROSIS. 2020;315:E14
- Conference publication: JOURNAL OF VASCULAR SURGERY. 2020;72(1):E265
- Meeting abstract: THE FASEB JOURNAL. 2020;34:1
- Conference publication: ATHEROSCLEROSIS. 2020;315:E22-E23
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;37:e190
- Conference publication: ATHEROSCLEROSIS. 2019;287:E27
- Corrigendum: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(5):2164
- Review: JOURNAL OF VASCULAR SURGERY. 2019;69(3):944-951
- Conference publication: JOURNAL OF VASCULAR RESEARCH. 2019;56:28
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;39
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;39
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;39
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2019;39
- Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2018;32:11-12
- Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2018;32:9
- Meeting abstract: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2018;38
- Meeting abstract: CARDIOVASCULAR RESEARCH (CVR). 2018;114:S138
- Conference publication: EUROPEAN HEART JOURNAL. 2018;39:660
- Conference publication: EUROPEAN HEART JOURNAL. 2018;39:524-525
- Conference publication: ATHEROSCLEROSIS. 2017;263:E8
- Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2017;65(6):23S-24S
- Conference publication: HEART. 2017;103:A137
- Conference publication: THE FASEB JOURNAL. 2017;31
- Conference publication: INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 2017;98(3):A5
- Conference publication: EUROPEAN HEART JOURNAL. 2017;38:1034
- Conference publication: JOURNAL OF VASCULAR RESEARCH. 2017;54:48
- Conference publication: JOURNAL OF VASCULAR RESEARCH. 2017;54:22
- Conference publication: JOURNAL OF VASCULAR RESEARCH. 2017;54:6
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):282
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):271-272
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2017;37
- Conference publication: THE FASEB JOURNAL. 2016;30
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36
- Conference publication: CARDIOVASCULAR RESEARCH (CVR). 2016;111:S106
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:956
- Corrigendum: PLOS ONE. 2015;10(5):e0126079
- Conference publication: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34
- Conference publication: EUROPEAN HEART JOURNAL. 2013;34:63-64
- Conference publication: CIRCULATION. 2013;128(22)
- Thesis / dissertation: 2012
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Forskningsbidrag
- Swedish Research Council1 January 2024 - 31 December 2026
- Swedish Research Council1 January 2022 - 31 December 2025
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2023
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2023
- Swedish Heart-Lung Foundation1 January 2021 - 31 December 2021
- Swedish Research Council1 January 2020 - 31 December 2023
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2020
- Swedish Heart-Lung Foundation1 January 2019 - 31 December 2020
- Swedish Research Council1 January 2018 - 31 December 2021
- Swedish Heart-Lung Foundation1 January 2018 - 31 December 2020
Anställningar
- Senior Forskare, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-
Examina och utbildning
- Docent, Molekylär medicin, Karolinska Institutet, 2021
- Medicine Doktorsexamen, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 2012