Lennart Hammarström

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Jag påbörjade min läkarutbildning vid Karolinska Institutet 1969 och efter kursen i immunologi 1971 så började jag forska (på deltid) hos Erna och Göran Möller. Efter avslutat grundutbildning så fortsatte jag med forskarutbildning på heltid och disputerade (och fick min docentur) 1979. Därefter fortsatte jag med min AT utbildning på kliniken och specialiserade mig så småningom inom klinisk immunologi (1984). Sedan dess har mitt arbete bestått av en blandning av klinik ock forskning.

Från början blev jag utnämnd till klinikchef för det kliniskt immunologiska laboratoriet (1977) men senare så koncentrerade jag mig mer på forskning och blev chef för avdelningen för Klinisk Immunologi (1999), samma år som jag utnämndes till professor (sedemera Distinguished professor, 2009) vid Karolinska Institutet. Jag innehar fortfarande denna post och avdelningen innefattar numera också transfusionsmedicin.

Forskningsbeskrivning

Jag har två huvudsakliga forskningsområden – immungenetik och immunterapi. Inom det första området så försöker vi finna den genetiska orsaken hos patienter med olika former av primär immunbrist. Detta görs genom homozygotimappning, exomsekvensiering och, på senare tid, helgenomsekvensiering. Patienterna kommer från olika infektionskliniker i Sverige men vi har också ett mycket omfattande internationellt samarbete. De senaste åren har vi dessutom påbörjat ett pilotprojekt med screening av nyfödda i Stockholmsregionen tillsammans med Centrum för Metabola sjukdomar och de barn som uppvisar tecken på immunbrist (brist på olika typer av vita blodkroppar – en metod som utformats av oss) utreds med avseende på genetiska defekter.

Inom immunterapiområdet så försöker vi utveckla nya former av behandling för våra patienter med immunbrist. Detta sker huvudsakligen med hjälp av antikroppar eller antikroppsfragment som produceras i mjölksyrebakterier (laktobaciller) och som kan bidra till passiv immunitet lokalt i mag-tarm kanalen under en begränsad period. Genom att välja laktobaciller som kan växa på olika ställen i magen/tarmen (tropism) så kan vi förebygga/behandla ett flertal olika infektioner och även en del andra sjukdomstillstånd.

Utvalda publikationer

Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(5):1380-1384.e5
RAC2 loss-of-function mutation in 2 siblings with characteristics of common variable immunodeficiency
Alkhairy OK; Rezaei N; Graham RR; Abolhassani H; Borte S; Hultenby K; Wu C; Aghamohammadi A; Williams DA; Behrens TW; Hammarstrom L; Pan-Hammarstrom Q
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(6):1375-1380
A hypomorphic recombination-activating gene 1 (RAG1) mutation resulting in a phenotype resembling common variable immunodeficiency
Abolhassani H; Wang N; Aghamohammadi A; Rezaei N; Lee YN; Frugoni F; Notarangelo LD; Pan-Hammarstrom Q; Hammarstrom L
Article: JOURNAL OF CLINICAL INVESTIGATION. 2013;123(9):3829-3838
Rice-based oral antibody fragment prophylaxis and therapy against rotavirus infection
Tokuhara D; Alvarez B; Mejima M; Hiroiwa T; Takahashi Y; Kurokawa S; Kuroda M; Oyama M; Kozuka-Hata H; Nochi T; Sagara H; Aladin F; Marcotte H; Frenken LGJ; Iturriza-Gomara M; Kiyono H; Hammarstrom L; Yuki Y
Article: SCIENCE. 2013;340(6135):976-978
Ribosomal Protein SA Haploinsufficiency in Humans with Isolated Congenital Asplenia
Bolze A; Mahlaoui N; Byun M; Turner B; Trede N; Ellis SR; Abhyankar A; Itan Y; Patin E; Brebner S; Sackstein P; Puel A; Picard C; Abel L; Quintana-Murci L; Faust SN; Williams AP; Baretto R; Duddridge M; Kini U; Pollard AJ; Gaud C; Frange P; Orbach D; Emile L-F; Stephan J-L; Sorensen R; Plebani A; Hammarstrom L; Conley ME; Selleri L; Casanova J-L
Article: BLOOD. 2012;119(11):2552-2555
Neonatal screening for severe primary immunodeficiency diseases using high-throughput triplex real-time PCR
Borte S; von Dobeln U; Fasth A; Wang N; Janzi M; Winiarski J; Sack U; Pan-Hammarstrom Q; Borte M; Hammarstrom L
Article: FRONTIERS IN IMMUNOLOGY. 2011;2:54
Primary immunodefciency diseases: an update on the classification from the International Union of Immunological Societies Expert Committee for Priary Immunodeficiency
Al-Herz W; Bousfiha A; Casanova J-L; Chapel H; Conley ME; Cunningham-Rundles C; Etzioni A; Fischer A; Luis Franco J; Geha RS; Hammarstrom L; Nonoyama S; Notarangelo LD; Ochs HD; Puck JM; Roifman CM; Seger R; Tang MLK
Article: NATURE GENETICS. 2010;42(9):777-U69
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Ferreira RC; Pan-Hammarstrom Q; Graham RR; Gateva V; Fontan G; Lee AT; Ortmann W; Urcelay E; Fernandez-Arquero M; Nunez C; Jorgensen G; Ludviksson BR; Koskinen S; Haimila K; Clark HF; Klareskog L; Gregersen PK; Behrens TW; Hammarstrom L

Artiklar

Article: ANNALS OF ALLERGY, ASTHMA AND IMMUNOLOGY. 2024;132(6):752-758.e2
Predominantly antibody deficiency and the association with celiac disease in Sweden A nationwide case-control study
DiGiacomo DV; Roelstraete B; Lebwohl B; Green PHR; Hammarstrom L; Farmer JR; Khalili H; Ludvigsson JF
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;44(4):86
COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report
McDonnell J; Cousins K; Younger MEM; Lane A; Abolhassani H; Abraham RS; Al-Tamemi S; Aldave-Becerra JC; Al-Faris EH; Alfaro-Murillo A; Alkhater SA; Alsaati N; Doss AMA; Anderson M; Angarola E; Ariue B; Arnold DE; Assa'ad AH; Aytekin C; Bank M; Bergerson JRE; Bleesing J; Boesing J; Bouso C; Brodszki N; Cabanillas D; Cady C; Callahan MA; Caorsi R; Carbone J; Carrabba M; Castagnoli R; Catanzaro JR; Chan S; Chandra S; Chapdelaine H; Chavoshzadeh Z; Chong HJ; Connors L; Consonni F; Correa-Jimenez O; Cunningham-Rundles C; D'Astous-Gauthier K; Delmonte OM; Demirdag YY; Deshpande DR; Diaz-Cabrera NM; Dimitriades VR; El-Owaidy R; Elghazali G; Al-Hammadi S; Fabio G; Faure AS; Feng J; Fernandez JM; Fill L; Franco GR; Frenck RW; Fuleihan RL; Giardino G; Galant-Swafford J; Gambineri E; Garabedian EK; Geerlinks AV; Goudouris E; Grecco O; Pan-Hammarstrom Q; Khani HHK; Hammarstrom L; Hartog NL; Heimall J; Hernandez-Molina G; Horner CC; Hostoffer RW; Hristova N; Hsiao K-C; Ivankovich-Escoto G; Jaber F; Jalil M; Jamee M; Jean T; Jeong S; Jhaveri D; Jordan MB; Joshi AY; Kalkat A; Kanarek HJ; Kellner ES; Khojah A; Khoury R; Kokron CM; Kumar A; Lecerf K; Lehman HK; Leiding JW; Lesmana H; Lim XR; Lopes JP; Lopez AL; Tarquini L; Lundgren IS; Magnusson J; Marinho AKBB; Marseglia GL; Martone GM; Mechtler AG; Mendonca L; Milner JD; Mustillo PJ; Naderi AG; Naviglio S; Nell J; Niebur HB; Notarangelo L; Oleastro M; Ortega-Lopez MC; Patel NR; Petrovic G; Pignata C; Porras O; Prince BT; Puck JM; Qamar N; Rabusin M; Raje N; Regairaz L; Risma KA; Ristagno EH; Routes J; Roxo-Junior P; Salemi N; Scalchunes C; Schuval SJ; Seneviratne SL; Shankar A; Sherkat R; Shin JJ; Siddiqi A; Signa S; Sobh A; Lima FMS; Stenehjem KK; Tam JS; Tang M; Barros MT; Verbsky J; Vergadi E; Voelker DH; Volpi S; Wall LA; Wang C; Williams KW; Wu EY; Wu SS; Zhou JJ; Cook A; Sullivan KE; Marsh R
Journal article: INTERNATIONAL JOURNAL OF NEONATAL SCREENING. 2024;10(2):30
Newborn Screening Today and Tomorrow: A Brief Report from the International Primary Immunodeficiencies Congress
Solis L; Van Coillie S; Bonham JR; Hauck F; Hammarstrom L; Staal FJT; Lim B; Pergent M; Prevot J
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2024;221(2):e20231353
Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children
Bastard P; Gervais A; Taniguchi M; Saare L; Sarekannu K; Le Voyer T; Philippot Q; Rosain J; Bizien L; Asano T; Garcia-Prat M; Parra-Martinez A; Migaud M; Tsumura M; Conti F; Belot A; Riviere JG; Morio T; Tanaka J; Javouhey E; Haerynck F; Duvlis S; Ozcelik T; Keles S; Tandjaoui-Lambiotte Y; Escoda S; Husain M; Pan-Hammarstrom Q; Hammarstrom L; Ahlijah G; Haidar AA; Soudee C; Arseguel V; Abolhassani H; Sahanic S; Tancevski I; Nukui Y; Hayakawa S; Chrousos GP; Michos A; Tatsi E-B; Filippatos F; Rodriguez-Palmero A; Troya J; Tipu I; Meyts I; Roussel L; Ostrowski SR; Schidlowski L; Prando C; Condino-Neto A; Cheikh N; Bousfiha AA; El Bakkouri J; Peterson P; Pujol A; Levy R; Quartier P; Vinh DC; Boisson B; Beziat V; Zhang S-Y; Borghesi A; Pession A; Andreakos E; Marr N; Mentis A-FA; Mogensen TH; Rodriguez-Gallego C; Soler-Palacin P; Colobran R; Tillmann V; Neven B; Trouillet-Assant S; Brodin P; Abel L; Jouanguy E; Zhang Q; Martinon-Torres F; Salas A; Gomez-Carballa A; Gonzalez-Granado LI; Kisand K; Okada S; Puel A; Cobat A; Casanova J-L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(3):e2315354120
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents Infection of Omicron lineages
Marcotte H; Cao Y; Zuo F; Simonelli L; Sammartino JC; Pedotti M; Sun R; Cassaniti I; Hagbom M; Piralla A; Yang J; Du L; Percivalle E; Bertoglio F; Schubert M; Abolhassani H; Sherina N; Guerra C; Borte S; Rezaei N; Kumagai-Braesch M; Xue Y; Su C; Yan Q; He P; Groenwall C; Klareskog L; Calzolai L; Cavalli A; Wang Q; Robbiani DF; Hust M; Shi Z; Feng L; Svensson L; Chen L; Bao L; Baldanti F; Xiao J; Qin C; Hammarstrom L; Yang X; Varani L; Xie XS; Pan-Hammarstrom Q
Article: NATURE COMMUNICATIONS. 2023;14(1):8124
IgG and IgM cooperate in coating of intestinal bacteria in IgA deficiency
Eriksen C; Moll JM; Myers PN; Pinto ARA; Danneskiold-Samsoe NB; Dehli RI; Rosholm LB; Dalgaard MD; Penders J; Jonkers DMAE; Pan-Hammarstrom Q; Hammarstrom L; Kristiansen K; Brix S
Article: NATURE. 2023;623(7988):803-813
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
Le Voyer T; Parent AV; Liu X; Cederholm A; Gervais A; Rosain J; Nguyen T; Lorenzo MP; Rackaityte E; Rinchai D; Zhang P; Bizien L; Hancioglu G; Ghillani-Dalbin P; Charuel J-L; Philippot Q; Gueye MS; Renkilaraj MRLM; Ogishi M; Soudee C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte OM; Mueller G; Keller B; Orrego J; Gallego WAF; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Raedler J; Bohlen J; Celik JB; Astudillo C; Winter S; McLean C; Guffroy A; DeRisi JL; Yu D; Miller C; Feng Y; Guichard A; Beziat V; Bustamante J; Pan-Hammarstrom Q; Zhang Y; Rosen LB; Holland SM; Bosticardo M; Kenney H; Castagnoli R; Slade CA; Boztug K; Mahlaoui N; Latour S; Abraham RS; Lougaris V; Hauck F; Sediva A; Atschekzei F; Sogkas G; Poli MC; Slatter MA; Palterer B; Keller MD; Pinzon-Charry A; Sullivan A; Droney L; Suan D; Wong M; Kane A; Hu H; Ma C; Grombirikova H; Ciznar P; Dalal I; Aladjidi N; Hie M; Lazaro E; Franco J; Keles S; Malphettes M; Pasquet M; Maccari ME; Meinhardt A; Ikinciogullari A; Shahrooei M; Celmeli F; Frosk P; Goodnow CC; Gray PE; Belot A; Kuehn HS; Rosenzweig SD; Miyara M; Licciardi F; Servettaz A; Barlogis V; Le Guenno G; Herrmann V-M; Kuijpers T; Ducoux G; Sarrot-Reynauld F; Schuetz C; Cunningham-Rundles C; Rieux-Laucat F; Tangye SG; Sobacchi C; Doffinger R; Warnatz K; Grimbacher B; Fieschi C; Berteloot L; Bryant VL; Assant ST; Su H; Neven B; Abel L; Zhang Q; Boisson B; Cobat A; Jouanguy E; Kampe O; Bastard P; Roifman CM; Landegren N; Notarangelo LD; Anderson MS; Casanova J-L; Puel A
Article: NATURE COMMUNICATIONS. 2023;14(1):6527
Design, structure and plasma binding of ancestral β-CoV scaffold antigens
Hueting D; Schriever K; Sun R; Vlachiotis S; Zuo F; Du L; Persson H; Hofstrom C; Ohlin M; Wallden K; Buggert M; Hammarstrom L; Marcotte H; Pan-Hammarstroem Q; Andrell J; Syren P-O
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;152(4):984-996.e10
Activated phosphoinositide 3-kinase d syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
Maccari ME; Wolkewitz M; Schwab C; Lorenzini T; Leiding JW; Aladjdi N; Abolhassani H; Abou-Chahla W; Aiuti A; Azarnoush S; Baris S; Barlogis V; Barzaghi F; Baumann U; Bloomfield M; Bohynikova N; Bodet D; Boutboul D; Bucciol G; Buckland MS; Burns SO; Cancrini C; Cath P; Cavazzana M; Cheminant M; Chinello M; Ciznar P; Coulter TI; D'Aveni M; Ekwall O; Eric Z; Eren E; Fasth A; Frange P; Fournier B; Garcia-Prat M; Gardembas M; Geier C; Ghosh S; Goda V; Hammarstrom L; Hauck F; Heeg M; Heropolitanska-Pliszka E; Hilfanova A; Jolles S; Karakoc-Aydiner E; Kindle GR; Kiykim A; Klemann C; Koletsi P; Koltan S; Kondratenko I; Korholz J; Kruger R; Jeziorski E; Levy R; Le Guenno G; Lefevre G; Lougaris V; Marzollo A; Mahlaoui N; Malphettes M; Meinhardt A; Merlin E; Meyts I; Milota T; Moreira F; Moshous D; Mukhina A; Neth O; Neubert J; Neven B; Nieters A; Nove-Josserand R; Oksenhendler E; Ozen A; Olbrich P; Perlat A; Pac M; Schmid JP; Pacillo L; Parra-Martinez A; Paschenko O; Pellier I; Sefer AP; Plebani A; Plantaz D; Prader S; Raffray L; Ritterbusch H; Riviere JG; Rivalta B; Rusch S; Sakovich I; Savic S; Scheible R; Schleinitz N; Schuetz C; Schulz A; Sediva A; Semeraro M; Sharapova SO; Shcherbina A; Slatter MA; Sogkas G; Soler-Palacin P; Speckmann C; Stephan J-L; Suarez F; Tommasini A; Truck J; Uhlmann A; van Aerde KJ; van Montfrans J; von Bernuth H; Warnatz K; Williams T; Worth AJJ; Ip W; Picard C; Catherinot E; Nademi Z; Grimbacher B; Satter LRF; Kracker S; Chandra A; Condliffe AM; Ehl S
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(6):1426-1435
Predominant Antibody Deficiency and Risk of Microscopic Colitis: a Nationwide Case-Control Study in Sweden
DiGiacomo DV; Roelstraete B; Hammarstrom L; Farmer JR; Khalili H; Ludvigsson JF
Article: INTERNATIONAL JOURNAL OF NEONATAL SCREENING. 2023;9(2):22
Genomic-Based Newborn Screening for Inborn Errors of Immunity: Practical and Ethical Considerations
King JR; Grill K; Hammarstrom L
Article: GENOME MEDICINE. 2023;15(1):22
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Abou Tayoun A; Aiuti A; Alavi Darazam I; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; El Zein L; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Metin Akcan O; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Effort COVIDHG; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(2):391-405
CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding, and Signaling Responses
Block V; Sevdali E; Recher M; Abolhassani H; Hammarstrom L; Smulski CR; Baronio M; Plebani A; Proietti M; Speletas M; Warnatz K; Voll RE; Lougaris V; Schneider P; Eibel H
Article: PHARMACEUTICS. 2022;15(1):63
Lactobacilli as a Vector for Delivery of Nanobodies against Norovirus Infection
Yuki Y; Zuo F; Kurokawa S; Uchida Y; Sato S; Sakon N; Hammarstroem L; Kiyono H; Marcotte H
Article: NATURE COMMUNICATIONS. 2022;13(1):6859
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits
Liu L; Khan A; Sanchez-Rodriguez E; Zanoni F; Li Y; Steers N; Balderes O; Zhang J; Krithivasan P; LeDesma RA; Fischman C; Hebbring SJ; Harley JB; Moncrieffe H; Kottyan LC; Namjou-Khales B; Walunas TL; Knevel R; Raychaudhuri S; Karlson EW; Denny JC; Stanaway IB; Crosslin D; Rauen T; Floege J; Eitner F; Moldoveanu Z; Reily C; Knoppova B; Hall S; Sheff JT; Julian BA; Wyatt RJ; Suzuki H; Xie J; Chen N; Zhou X; Zhang H; Hammarstrom L; Viktorin A; Magnusson PKE; Shang N; Hripcsak G; Weng C; Rundek T; Elkind MSV; Oelsner EC; Barr RG; Ionita-Laza I; Novak J; Gharavi AG; Kiryluk K
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;150(5):1059-1073
Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Abolhassani H; Delavari S; Landegren N; Shokri S; Bastard P; Du L; Zuo F; Hajebi R; Abolnezhadian F; Iranparast S; Modaresi M; Vosughimotlagh A; Salami F; Aranda-Guillen M; Cobat A; Marcotte H; Zhang S-Y; Zhang Q; Rezaei N; Casanova J-L; Kampe O; Hammarstrom L; Pan-Hammarstrom Q
Article: JOURNAL OF NEUROIMMUNOLOGY. 2022;371:577952
Meningoencephalitis in primary antibody deficiency: Our experience from northwest India
Jindal AK; Chaudhary H; Tyagi R; Rawat A; Suri D; Patra PK; Arora K; Chawla S; Vyas S; Arora M; Aggarwal R; Basu S; Bansal R; Sachdeva MUS; Gupta A; Pandiarajan V; Sankhyan N; Suthar R; Sahu JK; Singh M; Mani R; Sharma R; Saka R; Imai K; Ohara O; Nonoyama S; Hammarstrom L; Chan KW; Lau YL; Singh S
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(10):e20220094
Impaired IL-23-dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency
Ogishi M; Augusto Arias A; Yang R; Han JE; Zhang P; Rinchai D; Halpern J; Mulwa J; Keating N; Chrabieh M; Laine C; Seeleuthner Y; Ramirez-Alejo N; Nekooie-Marnany N; Guennoun A; Muller-Fleckenstein I; Fleckenstein B; Kilic SS; Minegishi Y; Ehl S; Kaiser-Labusch P; Kendir-Demirkol Y; Rozenberg F; Errami A; Zhang S-Y; Zhang Q; Bohlen J; Puel A; Jouanguy E; Pourmoghaddas Z; Bakhtiar S; Willasch AM; Horneff G; Llanora G; Shek LP; Chai LYA; Tay SH; Rahimi HH; Mahdaviani SA; Nepesov S; Bousfiha AA; Erdeniz EH; Karbuz A; Marr N; Navarrete C; Adeli M; Hammarstrom L; Abolhassani H; Parvaneh N; Al Muhsen S; Alosaimi MF; Alsohime F; Nourizadeh M; Moin M; Arnaout R; Alshareef S; El-Baghdadi J; Genel F; Sherkat R; Kiykim A; Yucel E; Keles S; Bustamante J; Abel L; Casanova J-L; Boisson-Dupuis S
Article: BLOOD ADVANCES. 2022;6(18):5403-5414
Genomic characterization of lymphomas in patients with inborn errors of immunity
Ye X; Maglione PJ; Wehr C; Li X; Wang Y; Abolhassani H; Deripapa E; Liu D; Borte S; Du L; Wan H; Ploetner A; Giannoula Y; Ko H-B; Hou Y; Zhu S; Grossman JK; Sander B; Grimbacher B; Hammarstrom L; Fedorova A; Rosenzweig SD; Shcherbina A; Wu K; Warnatz K; Cunningham-Rundles C; Pan-Hammarstrom Q
Article: BRIEFINGS IN BIOINFORMATICS. 2022;23(5):bbac176
VIPPID: a gene-specific single nucleotide variant pathogenicity prediction tool for primary immunodeficiency diseases
Fang M; Su Z; Abolhassani H; Itan Y; Jin X; Hammarstrom L
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(8):e20220131
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Zhang Q; Matuozzo D; Le Pen J; Lee D; Moens L; Asano T; Bohlen J; Liu Z; Moncada-Velez M; Kendir-Demirkol Y; Jing H; Bizien L; Marchal A; Abolhassani H; Delafontaine S; Bucciol G; Bayhan GI; Keles S; Kiykim A; Hancerli S; Haerynck F; Florkin B; Hatipoglu N; Ozcelik T; Morelle G; Zatz M; Ng LFP; Lye DC; Young BE; Leo Y-S; Dalgard CL; Lifton RP; Renia L; Meyts I; Jouanguy E; Hammarstrom L; Pan-Hammarstrom Q; Boisson B; Bastard P; Su HC; Boisson-Dupuis S; Abel L; Rice CM; Zhang S-Y; Cobat A; Casanova J-L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(21):e2200413119
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Manry J; Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly S; Bourkeh NM; Halwan R; Sharif-Askar FS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Erikstrup C; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Burdet C; Bouadma L; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; D Notarangelo L; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Casanova J-L; Abel L; Cobat A
Article: NATURE COMMUNICATIONS. 2022;13(1):2670
Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant
Zuo F; Abolhassani H; Du L; Piralla A; Bertoglio F; de Campos-Mata L; Wan H; Schubert M; Cassaniti I; Wang Y; Sammartino JC; Sun R; Vlachiotis S; Bergami F; Kumagai-Braesch M; Andrell J; Zhang Z; Xue Y; Wenzel EV; Calzolai L; Varani L; Rezaei N; Chavoshzadeh Z; Baldanti F; Hust M; Hammarstrom L; Marcotte H; Pan-Hammarstrom Q
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL. 2022;1(2):37-42
Lung function before and after COVID-19 in young adults: A population-based study.
Mogensen I; Hallberg J; Björkander S; Du L; Zuo F; Hammarström L; Pan-Hammarström Q; Ekström S; Georgelis A; Palmberg L; Janson C; Bergström A; Melén E; Kull I; BAMSE COVID-19 Study Group
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(3):618-633
Long-Term Follow-Up of Newborns with 22q11 Deletion Syndrome and Low TRECs
Framme JL; Lundqvist C; Lundell A-C; van Schouwenburg PA; Lemarquis AL; Thorn K; Lindgren S; Gudmundsdottir J; Lundberg V; Degerman S; Zetterstrom RH; Borte S; Hammarstrom L; Telemo E; Hultdin M; van der Burg M; Fasth A; Oskarsdottir S; Ekwall O
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(3):471-483
Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome
Abolhassani H; Landegren N; Bastard P; Materna M; Modaresi M; Du L; Aranda-Guillen M; Sardh F; Zuo F; Zhang P; Marcotte H; Marr N; Khan T; Ata M; Al-Ali F; Pescarmona R; Belot A; Beziat V; Zhang Q; Casanova J-L; Kampe O; Zhang S-Y; Hammarstrom L; Pan-Hammarstrom Q
Article: BMC MEDICINE. 2022;20(1):102
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
Schubert M; Bertoglio F; Steinke S; Heine PA; Ynga-Durand MA; Maass H; Sammartino JC; Cassaniti I; Zuo F; Du L; Korn J; Milosevic M; Wenzel EV; Krstanovic F; Polten S; Pribanic-Matesic M; Brizic I; Baldanti F; Hammarstrom L; Duebel S; Sustic A; Marcotte H; Strengert M; Protic A; Piralla A; Pan-Hammarstroem Q; Cicin-Sain L; Hust M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(3):1069-1084
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
He M; Saeed MB; Record J; Keszei M; Pinho LG; Vasconcelos-Fontes L; D'Aulerio R; Vieira R; Oliveira MMS; Geyer C; Bohaumilitzky L; Thiemann M; Deordieva E; Buedts L; Lopes JPM; Pershin D; Hammarstrom L; Xia Y; Zhao X; Cunningham-Rundles C; Thrasher AJ; Burns SO; Cotta-de-Almeida V; Liu C; Shcherbina A; Vandenberghe P; Westerberg LS
Article: ISCIENCE. 2022;25(2):103743
Immunity to SARS-CoV-2 up to 15 months after infection
Marcotte H; Piralla A; Zuo F; Du L; Cassaniti I; Wan H; Kumagai-Braesh M; Andrell J; Percivalle E; Sammartino JC; Wang Y; Vlachiotis S; Attevall J; Bergami F; Ferrari A; Colaneri M; Vecchia M; Sambo M; Zuccaro V; Asperges E; Bruno R; Oggionni T; Meloni F; Abolhassani H; Bertoglio F; Schubert M; Calzolai L; Varani L; Hust M; Xue Y; Hammarstrom L; Baldanti F; Pan-Hammarstrom Q
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(2):375-393
T Cell Repertoire Abnormality in Immunodeficiency Patients with DNA Repair and Methylation Defects
Fang M; Su Z; Abolhassani H; Zhang W; Jiang C; Cheng B; Luo L; Wu J; Wang S; Lin L; Wang X; Wang L; Aghamohammadi A; Li T; Zhang X; Hammarstrom L; Liu X
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:965326
Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50
Fliegauf M; Kinnunen M; Posadas-Cantera S; Camacho-Ordonez N; Abolhassani H; Alsina L; Atschekzei F; Bogaert DJ; Burns SO; Church JA; Dueckers G; Freeman AF; Hammarstroem L; Hanitsch LG; Kerre T; Kobbe R; Sharapova SO; Siepermann K; Speckmann C; Steiner S; Verma N; Walter JE; Westermann-Clark E; Goldacker S; Warnatz K; Varjosalo M; Grimbacher B
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(1):1-9
X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia
Abolhassani H; Vosughimotlagh A; Asano T; Landegren N; Boisson B; Delavari S; Bastard P; Aranda-Guillen M; Wang Y; Zuo F; Sardh F; Marcotte H; Du L; Zhang S-Y; Zhang Q; Rezaei N; Kampe O; Casanova J-L; Hammarstrom L; Pan-Hammarstrom Q
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):65-75.e8
SARS-CoV-2-specific B- and T-cell immunity in a population-based study of young Swedish adults
Bjorkander S; Du L; Zuo F; Ekstrom S; Wang Y; Wan H; Sherina N; Schoutens L; Andrell J; Andersson N; Georgelis A; Bergstrom A; Marcotte H; Kull I; Hammarstrom L; Melen E; Pan-Hammarstrom Q
Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4348
X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19
Asano T; Boisson B; Onodi F; Matuozzo D; Moncada-Velez M; Renkilaraj MRLM; Zhang P; Meertens L; Bolze A; Materna M; Korniotis S; Gervais A; Talouarn E; Bigio B; Seeleuthner Y; Bilguvar K; Zhang Y; Neehus A-L; Ogishi M; Pelham SJ; Le Voyer T; Rosain J; Philippot Q; Soler-Palacin P; Colobran R; Martin-Nalda A; Riviere JG; Tandjaoui-Lambiotte Y; Chaibi K; Shahrooei M; Darazam IA; Olyaei NA; Mansouri D; Palabiyik F; Ozcelik T; Novelli G; Novelli A; Casari G; Aiuti A; Carrera P; Bondesan S; Barzaghi F; Rovere-Querini P; Tresoldi C; Franco JL; Rojas J; Reyes LF; Bustos IG; Arias AA; Morelle G; Kyheng C; Troya J; Planas-Serra L; Schluter A; Gut M; Pujol A; Allende LM; Rodriguez-Gallego C; Flores C; Cabrera-Marante O; Pleguezuelo DE; de Diego RP; Keles S; Aytekin G; Akcan OM; Bryceson YT; Bergman P; Brodin P; Smole D; Smith CIE; Norlin A-C; Campbell TM; Covill LE; Hammarstrom L; Pan-Hammarstrom Q; Abolhassani H; Mane S; Marr N; Ata M; Al Ali F; Khan T; Spaan AN; Dalgard CL; Bonfanti P; Biondi A; Tubiana S; Burdet C; Nussbaum R; Kahn-Kirby A; Snow AL; Bustamante J; Puel A; Boisson-Dupuis S; Zhang S-Y; Beziat V; Lifton RP; Bastard P; Notarangelo LD; Abel L; Su HC; Jouanguy E; Amara A; Soumelis V; Cobat A; Zhang Q; Casanova J-L
Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4340
Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths
Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Manry J; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Coulibaly B; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Nussbaum RL; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly SP; Bourke NM; Halwani R; Sharif-Askari NS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Ostrowski SR; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Duval X; Mentre F; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; Notarangelo LD; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Cobat A; Abel L; Casanova J-L
Article: IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY. 2021;20(4):402-412
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies
Shakerian L; Nourizadeh M; Badalzadeh M; Fazlollahi MR; Shoormasti RS; Saghafi S; Esmaeili B; Alizadeh Z; Borte S; Houshmand M; Hammarstrom L; Pourpak Z
Article: GASTROENTEROLOGY. 2021;160(7):2423-2434.e5
Gut Microbiota Perturbation in IgA Deficiency Is Influenced by IgA-Autoantibody Status
Moll JM; Myers PN; Zhang C; Eriksen C; Wolf J; Appelberg KS; Lindberg G; Bahl MI; Zhao H; Pan-Hammarstroem Q; Cai K; Jia H; Borte S; Nielsen HB; Kristiansen K; Brix S; Hammarstrom L
Article: NUCLEIC ACIDS RESEARCH (NAR). 2021;49(9):5057-5073
Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction
Catala-Moll F; Ferrete-Bonastre AG; Li T; Weichenhan D; Lutsik P; Ciudad L; Alvarez-Prado AF; Rodriguez-Ubreva J; Klemann C; Speckmann C; Vilas-Zornoza A; Abolhassani H; Martinez-Gallo M; Dieli-Crimi R; Riviere JG; Martin-Nalda A; Colobran R; Soler-Palacin P; Kracker S; Hammarstrom L; Prosper F; Durandy A; Grimbacher B; Plass C; Ballestar E
Article: MED. 2021;2(3):281-295.e4
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6-8 months after the infection
Sherina N; Piralla A; Du L; Wan H; Kumagai-Braesch M; Andrell J; Braesch-Andersen S; Cassaniti I; Percivalle E; Sarasini A; Bergami F; Di Martino R; Colaneri M; Vecchia M; Sambo M; Zuccaro V; Bruno R; Sachs M; Oggionni T; Meloni F; Abolhassani H; Bertoglio F; Schubert M; Byrne-Steele M; Han J; Hust M; Xue Y; Hammarstrom L; Baldanti F; Marcotte H; Pan-Hammarstrom Q
Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(3):142434
Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency
Pillay BA; Fusaro M; Gray PE; Statham AL; Burnett L; Bezrodnik L; Kane A; Tong W; Abdo C; Winter S; Chevalier S; Levy R; Masson C; Schmitt Y; Bole C; Malphettes M; Macintyre E; Villartay J-PD; Ziegler JB; Smart JM; Peake J; Aghamohammadi A; Hammarstrom L; Abolhassani H; Picard C; Fischer A; Latour S; Neven B; Tangye SG; Ma CS
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2021;41(2):345-355
Impact of SARS-CoV-2 Pandemic on Patients with Primary Immunodeficiency
Delavari S; Abolhassani H; Abolnezhadian F; Babaha F; Iranparast S; Ahanchian H; Moazzen N; Nabavi M; Arshi S; Fallahpour M; Bemanian MH; Shokri S; Momen T; Sadeghi-Shabestari M; Molatefi R; Shirkani A; Vosughimotlagh A; Safarirad M; Sharifzadeh M; Pashangzadeh S; Salami F; Shirmast P; Rezaei A; Shad TM; Mohraz M; Rezaei N; Hammarstrom L; Yazdani R; Aghamohamamdi A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(2):428-438
An appraisal of the Wilson & Jungner criteria in the context of genomic-based newborn screening for inborn errors of immunity
King JR; Notarangelo LD; Hammarstrom L
Article: FRONTIERS IN GENETICS. 2021;12:736235
STXBP6 and B3GNT6 Genes are Associated With Selective IgA Deficiency
Lim CK; Bronson PG; Varade J; Behrens TW; Hammarstroem L
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:667336
Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations
Creary LE; Gangavarapu S; Caillier SJ; Cavalcante P; Frangiamore R; Lie BA; Bengtsson M; Harbo HF; Brauner S; Hollenbach JA; Oksenberg JR; Bernasconi P; Maniaol AH; Hammarstrom L; Mantegazza R; Fernandez-Vina MA
Article: BLOOD. 2020;136(23):2638-2655
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency
Ghosh S; Bal SK; Edwards ESJ; Pillay B; Heredia RJ; Cipe FE; Rao G; Salzer E; Zoghi S; Abolhassani H; Momen T; Gostick E; Price DA; Zhang Y; Oler AJ; Gonzaga-Jauregui C; Erman B; Metin A; Ilhan I; Haskologlu S; Islamoglu C; Baskin K; Ceylaner S; Yilmaz E; Unal E; Karakukcu M; Berghuis D; Cole T; Gupta AK; Hauck F; Kogler H; Hoepelman AIM; Baris S; Karakoc-Aydiner E; Ozen A; Kager L; Holzinger D; Paulussen M; Krueger R; Meisel R; Oommen PT; Morris E; Neven B; Worth A; van Montfrans J; Fraaij PLA; Choo S; Dogu F; Davies EG; Burns S; Duckers G; Becker RP; von Bernuth H; Latour S; Faraci M; Gattorno M; Su HC; Pan-Hammarstroem Q; Hammarstroem L; Lenardo MJ; Ma CS; Niehues T; Aghamohammadi A; Rezaei N; Ikinciogullari A; Tangye SG; Lankester AC; Boztug K
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;146(4):901-911
Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations
Lorenzini T; Fliegauf M; Klammer N; Frede N; Proietti M; Bulashevska A; Camacho-Ordonez N; Varjosalo M; Kinnunen M; de Vries E; van der Meer JWM; Ameratunga R; Roifman CM; Schejter YD; Kobbe R; Hautala T; Atschekzei F; Schmidt RE; Schroeder C; Stepensky P; Shadur B; Pedroza LA; van der Flier M; Martinez-Gallo M; Gonzalez-Granado LI; Allende LM; Shcherbina A; Kuzmenko N; Zakharova V; Neves JF; Svec P; Fischer U; Ip W; Bartsch O; Baris S; Klein C; Geha R; Chou J; Alosaimi M; Weintraub L; Boztug K; Hirschmugl T; Dos Santos Vilela MM; Holzinger D; Seidl M; Lougaris V; Plebani A; Alsina L; Piquer-Gibert M; Deya-Martinez A; Slade CA; Aghamohammadi A; Abolhassani H; Hammarstrom L; Kuismin O; Helminen M; Allen HL; Thaventhiran JE; Freeman AF; Cook M; Bakhtiar S; Christiansen M; Cunningham-Rundles C; Patel NC; Rae W; Niehues T; Brauer N; Syrjanen J; Seppanen MRJ; Burns SO; Tuijnenburg P; Kuijpers TW; Warnatz K; Grimbacher B
Article: JOURNAL OF INFECTIOUS DISEASES. 2020;222(3):470-478
A Heterodimeric Antibody Fragment for Passive Immunotherapy Against Norovirus Infection
Yuki Y; Kurokawa S; Sato S; Sasou A; Matsumoto N; Suzuki A; Sakon N; Goda Y; Takeyama N; Miyoshi T; Marcotte H; Tanaka T; Hammarstrom L; Kiyono H
Article: CLINICAL GENETICS. 2020;97(6):844-856
Clinical implications of experimental analyses of AID function on predictive computational tools: Challenge of missense variants
Abolhassani H; Marcotte H; Fang M; Hammarstrom L
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2020;9(5):e1130
Defective formation of IgA memory B cells, Th1 and Th17 cells in symptomatic patients with selective IgA deficiency
Grosserichter-Wagener C; Franco-Gallego A; Ahmadi F; Moncada-Velez M; Dalm VASH; Lineth Rojas J; Cesar Orrego J; Vargas NC; Hammarstrom L; Schreurs MWJ; Dik WA; van Hagen PM; Boon L; van Dongen JJM; van der Burg M; Pan-Hammarstrom Q; Franco JL; van Zelm MC
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(5):1452-1463
Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score
Tesch VK; Abolhassani H; Shadur B; Zobel J; Mareika Y; Sharapova S; Karakoc-Aydiner E; Riviere JG; Garcia-Prat M; Moes N; Haerynck F; Gonzales-Granado LI; Santos Perez JL; Mukhina A; Shcherbina A; Aghamohammadi A; Hammarstrom L; Dogu F; Haskologlu S; Ikinciogullari AI; Bal SK; Baris S; Kilic SS; Karaca NE; Kutukculer N; Girschick H; Kolios A; Keles S; Uygun V; Stepensky P; Worth A; van Montfrans JM; Peters AMJ; Meyts I; Adeli M; Marzollo A; Padem N; Khojah AM; Chavoshzadeh Z; Stefanija MA; Bakhtiar S; Florkin B; Meeths M; Gamez L; Grimbacher B; Seppanen MRJ; Lankester A; Gennery AR; Seidel MG
Article: ANNUAL REVIEW OF ANIMAL BIOSCIENCES. 2020;8:145-169
The Immunoglobulins: New Insights, Implications, and Applications
Sun Y; Huang T; Hammarstrom L; Zhao Y
Article: SCIENCE IMMUNOLOGY. 2020;5(44):eaay5864
Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination
Rothschild G; Zhang W; Lim J; Giri PK; Laffleur B; Chen Y; Fang M; Chen Y; Nair L; Liu Z-P; Deng H; Hammarstrom L; Wang J; Basu U
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2020;40(2):277-288
Expanding Clinical Phenotype and Novel Insights into the Pathogenesis of ICOS Deficiency
Abolhassani H; El-Sherbiny YM; Arumugakani G; Carter C; Richards S; Lawless D; Wood P; Buckland M; Heydarzadeh M; Aghamohammadi A; Hambleton S; Hammarstrom L; Burns SO; Doffinger R; Savic S
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:14
Histocompatibility Complex Status and Mendelian Randomization Analysis in Unsolved Antibody Deficiency
Abolhassani H; Lim CK; Aghamohammadi A; Hammarstrom L
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:455
Newborn Screening for Presymptomatic Diagnosis of Complement and Phagocyte Deficiencies
Dezfouli M; Bergstrom S; Skattum L; Abolhassani H; Neiman M; Torabi-Rahvar M; Franco Jarava C; Martin-Nalda A; Ferrer Balaguer JM; Slade CA; Roos A; Fernandez Pereira LM; Lopez-Trascasa M; Gonzalez-Granado LI; Allende-Martinez LM; Mizuno Y; Yoshida Y; Friman V; Lundgren A; Aghamohammadi A; Rezaei N; Hernandez-Gonzalez M; von Dobeln U; Truedsson L; Hara T; Nonoyama S; Schwenk JM; Nilsson P; Hammarstrom L
Article: JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY. 2019;8(6):507-518
Fucosyltransferase Gene Polymorphisms and Lewis^b-Negative Status Are Frequent in Swedish Newborns, With Implications for Infectious Disease Susceptibility and Personalized Medicine
King JR; Varade J; Hammarstrom L
Article: STEM CELL RESEARCH. 2019;41:101613
Generation of human induced pluripotent stem cell lines from patients with selective IgA deficiency
Arias-Fuenzalida J; Yu J; Du L; Custodio J; Notarangelo LD; Hammarstrom L; Pan-Hammarstrom Q
Article: ACS SYNTHETIC BIOLOGY. 2019;8(8):1723-1729
Inducible Plasmid Self-Destruction (IPSD) Assisted Genome Engineering in Lactobacilli and Bifidobacteria
Zuo F; Zeng Z; Hammarstrom L; Marcotte H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(6):e12763
Challenges in investigating patients with isolated decreased serum IgM: The SIMcal study
Janssen LMA; van Hout RWNM; de Vries E; Pignata C; Cirillo E; Arkwright PD; Lougaris V; Buckland M; Garcia-Prat M; Soler-Palacin P; Ouederni M; Kralickova P; Abolhassani H; Hammerstroem L; Aghamohammadi A; Santos-Perez JL; Sobh A; ten Bosch JVDW; Henriet S; Kilic SS; Karali Y; Ignacio Gonzalez-Granado L; Sediva A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2019;7(3):864-878.e9
Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort
Yazdani R; Abolhassani H; Kiaee F; Habibi S; Azizi G; Tavakol M; Chavoshzadeh Z; Mahdaviani SA; Momen T; Gharagozlou M; Movahedi M; Hamidieh AA; Behniafard N; Nabavi M; Bemanian MH; Arshi S; Molatefi R; Sherkat R; Shirkani A; Amin R; Aleyasin S; Faridhosseini R; Jabbari-Azad F; Mohammadzadeh I; Ghaffari J; Shafiei A; Kalantari A; Mansouri M; Mesdaghi M; Babaie D; Ahanchian H; Khoshkhui M; Soheili H; Eslamian MH; Cheraghi T; Dabbaghzadeh A; Tavassoli M; Kalmarzi RN; Mortazavi SH; Kashef S; Esmaeilzadeh H; Tafaroji J; Khalili A; Zandieh F; Sadeghi-Shabestari M; Darougar S; Behmanesh F; Akbari H; Zandkarimi M; Abolnezhadian F; Fayezi A; Moghtaderi M; Ahmadiafshar A; Shakerian B; Sajedi V; Taghvaei B; Safari M; Heidarzadeh M; Ghalebaghi B; Fathi SM; Darabi B; Bazregari S; Bazargan N; Fallahpour M; Khayatzadeh A; Javahertrash N; Bashardoust B; Zamani M; Mohsenzadeh A; Ebrahimi S; Sharafian S; Vosughimotlagh A; Tafakoridelbari M; Rahim M; Ashournia P; Razaghian A; Rezaei A; Samavat A; Mamishi S; Khazaei HA; Mohammadi J; Negahdari B; Parvaneh N; Rezaei N; Lougaris V; Giliani S; Plebani A; Ochs HD; Hammarstrom L; Aghamohammadi A
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2503
Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden
Silva SL; Fonseca M; Pereira MLM; Silva SP; Barbosa RR; Serra-Caetano A; Blanco E; Rosmaninho P; Perez-Andres M; Sousa AB; Raposo AASF; Gama-Carvalho M; Victorino RM; Hammarstrom L; de Sousa AE
Article: GENETICS IN MEDICINE. 2019;21(1):243-251
Clinical implications of systematic phenotyping and exome sequencing in patients with primary antibody deficiency
Abolhassani H; Aghamohammadi A; Fang M; Rezaei N; Jiang C; Liu X; Pan-Hammarstrom Q; Hammarstrom L
Article: SCIENCE IMMUNOLOGY. 2018;3(30):eaau8714
Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
Boisson-Dupuis S; Ramirez-Alejo N; Li Z; Patin E; Rao G; Kerner G; Lim CK; Krementsov DN; Hernandez N; Ma CS; Zhang Q; Markle J; Martinez-Barricarte R; Payne K; Fisch R; Deswarte C; Halpern J; Bouaziz M; Mulwa J; Sivanesan D; Lazarov T; Naves R; Garcia P; Itan Y; Boisson B; Checchi A; Jabot-Hanin F; Cobat A; Guennoun A; Jackson CC; Pekcan S; Caliskaner Z; Inostroza J; Costa-Carvalho BT; Tavares de Albuquerque JA; Garcia-Ortiz H; Orozco L; Ozcelik T; Abid A; Rhorfi IA; Souhi H; Amrani HN; Zegmout A; Geissmann F; Michnick SW; Muller-Fleckenstein I; Fleckenstein B; Puel A; Ciancanelli MJ; Marr N; Abolhassani H; Elvira Balcells M; Condino-Neto A; Strickler A; Abarca K; Teuscher C; Ochs HD; Reisli I; Sayar EH; El-Baghdadi J; Bustamante J; Hammarstrom L; Tangye SG; Pellegrini S; Quintana-Murci L; Abel L; Casanova J-L
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(6):1922-1931.e2
Predictive markers for humoral influenza vaccine response in patients with common variable immunodeficiency
Gardulf A; Abolhassani H; Gustafson R; Eriksson LE; Hammarstrom L
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2018;29(8):863-872
Targeted next-generation sequencing for genetic diagnosis of 160 patients with primary immunodeficiency in south China
Xia Y; He T; Luo Y; Li C; Lim CK; Abolhassani H; Yang J; Hammarstrom L
Article: CLINICAL IMMUNOLOGY. 2018;197:40-44
Defective TLR9-driven STAT3 activation in B cells of patients with CVID
Borzutzky A; Rauter I; Fried A; Rachid R; McDonald DR; Hammarstrom L; Grimbacher B; Abraham RS; Geha RS
Article: PLOS MEDICINE. 2018;15(12):e1002717
Small for gestational age and risk of childhood mortality: A Swedish population study
Ludvigsson JF; Lu D; Hammarstrom L; Cnattingius S; Fang F
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2018;38(7):816-832
Fourth Update on the Iranian National Registry of Primary Immunodeficiencies: Integration of Molecular Diagnosis
Abolhassani H; Kiaee F; Tavakol M; Chavoshzadeh Z; Mahdaviani SA; Momen T; Yazdani R; Azizi G; Habibi S; Gharagozlou M; Movahedi M; Hamidieh AA; Behniafard N; Nabavi M; Bemanian MH; Arshi S; Molatefi R; Sherkat R; Shirkani A; Amin R; Aleyasin S; Faridhosseini R; Jabbari-Azad F; Mohammadzadeh I; Ghaffari J; Shafiei A; Kalantari A; Mansouri M; Mesdaghi M; Babaie D; Ahanchian H; Khoshkhui M; Soheili H; Eslamian MH; Cheraghi T; Dabbaghzadeh A; Tavassoli M; Kalmarzi RN; Mortazavi SH; Kashef S; Esmaeilzadeh H; Tafaroji J; Khalili A; Zandieh F; Sadeghi-Shabestari M; Darougar S; Behmanesh F; Akbari H; Zandkarimi M; Abolnezhadian F; Fayezi A; Moghtaderi M; Ahmadiafshar A; Shakerian B; Sajedi V; Taghvaei B; Safari M; Heidarzadeh M; Ghalebaghi B; Fathi SM; Darabi B; Bazregari S; Bazargan N; Fallahpour M; Khayatzadeh A; Javahertrash N; Bashardoust B; Zamani M; Mohsenzadeh A; Ebrahimi S; Sharafian S; Vosughimotlagh A; Tafakoridelbari M; Rahimi M; Ashournia P; Razaghian A; Rezaei A; Mamishi S; Parvaneh N; Rezaei N; Hammarstrom L; Aghamohammadi A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;88(2):e12699
Newborn screening using TREC/KREC assay for severe T and B cell lymphopenia in Iran
Nourizadeh M; Shakerian L; Borte S; Fazlollahi M; Badalzadeh M; Houshmand M; Alizadeh Z; Dalili H; Rashidi-Nezhad A; Kazemnejad A; Moin M; Hammarstrom L; Pourpak Z
Article: IMMUNOLOGICAL INVESTIGATIONS. 2018;47(5):457-467
Polyautoimmunity in Patients with LPS-Responsive Beige-Like Anchor (LRBA) Deficiency
Azizi G; Abolhassani H; Zaki-Dizaji M; Habibi S; Mohammadi H; Shaghaghi M; Yazdani R; Anaya J-M; Rezaei N; Hammarstrom L; Aghamohammadi A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(4):1450-1458
Clinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency
Abolhassani H; Chou J; Bainter W; Platt CD; Tavassoli M; Momen T; Tavakol M; Eslamian MH; Gharagozlou M; Movahedi M; Ghadami M; Hamidieh AA; Azizi G; Yazdani R; Afarideh M; Ghajar A; Havaei A; Chavoshzadeh Z; Mahdaviani SA; Cheraghi T; Behniafard N; Amin R; Aleyasin S; Faridhosseini R; Jabbari-Azad F; Nabavi M; Bemanian MH; Arshi S; Molatefi R; Sherkat R; Mansouri M; Mesdaghi M; Babaie D; Mohammadzadeh I; Ghaffari J; Shafiei A; Kalantari N; Ahanchian H; Khoshkhui M; Soheili H; Dabbaghzadeh A; Shirkani A; Kalmarzi RN; Mortazavi SH; Tafaroji J; Khalili A; Mohammadi J; Negahdari B; Joghataei M-T; al-Ramadi BK; Picard C; Parvaneh N; Rezaei N; Chatila TA; Massaad MJ; Keles S; Hammarstrom L; Geha RS; Aghamohammadi A
Article: GIGASCIENCE. 2018;7(3):1-8
Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing.
Fang C; Zhong H; Lin Y; Chen B; Han M; Ren H; Lu H; Luber JM; Xia M; Li W; Stein S; Xu X; Zhang W; Drmanac R; Wang J; Yang H; Hammarström L; Kostic AD; Kristiansen K; Li J
Article: CLINICAL IMMUNOLOGY. 2018;188:94-102
Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity
Hou TZ; Olbrich P; Lucena Soto JM; Sanchez B; Sanchez Moreno P; Borte S; Stauss HJ; Burns SO; Walker LSK; Pan-Hammarstrom Q; Hammarstrom L; Sansom DM; Neth O
Article: JOURNAL OF AUTOIMMUNITY. 2018;88:43-49
Novel genetic loci associated HLA-B*08:01 positive myasthenia gravis
Varade J; Wang N; Lim CK; Zhang T; Zhang Y; Liu X; Piehl F; Matell R; Cao H; Xu X; Hammarstrom L
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(2):770-775.e1
Treatment of severe forms of LPS-responsive beige-like anchor protein deficiency with allogeneic hematopoietic stem cell transplantation
Seidel MG; Boehm K; Dogu F; Worth A; Thrasher A; Florkin B; Ikinciogullari A; Peters A; Bakhtiar S; Meeths M; Stepensky P; Meyts I; Sharapova SO; Gamez-Diaz L; Hammarstroem L; Ehl S; Grimbacher B; Gennery AR
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(1):408-411.e8
Reduced immunoglobulin gene diversity in patients with Cornelia de Lange syndrome
Bjorkman A; Du L; van der Burg M; Cormier-Daire V; Borck G; Pie J; Anderlid B-M; Hammarstrom L; Strom L; de Villartay J-P; Kipling D; Walters DD; Pan-Hammarstrom Q
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2018;38(1):56-66
Newborn Screening for Primary Immunodeficiency Diseases: History, Current and Future Practice
King JR; Hammarstrom L
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:543
Disease evolution and response to rapamycin in Activated Phosphoinositide 3-Kinase δ syndrome: the european society for immunodeficiencies-Activated Phosphoinositide 3-Kinase d syndrome registry
Maccari ME; Abolhassani H; Aghamohammadi A; Aiuti A; Aleinikova O; Bangs C; Baris S; Barzaghi F; Baxendale H; Buckland M; Burns SO; Cancrini C; Cant A; Cathebras P; Cavazzana M; Chandra A; Conti F; Coulter T; Devlin LA; Edgar JDM; Faust S; Fischer A; Prat MG; Hammarstrom L; Heeg M; Jolles S; Karakoc-Aydiner E; Kindle G; Kiykim A; Kumararatne D; Grimbacher B; Longhurst H; Mahlaoui N; Milota T; Moreira F; Moshous D; Mukhina A; Neth O; Neven B; Nieters A; Olbrich P; Ozen A; Schmid JP; Picard C; Prader S; Rae W; Reichenbach J; Rusch S; Savic S; Scarselli A; Scheible R; Sediva A; Sharapova SO; Shcherbina A; Slatter M; Soler-Palacin P; Stanislas A; Suarez F; Tucci F; Uhlmann A; van Montfrans J; Warnatz K; Williams AP; Wood P; Kracker S; Condliffe AM; Ehl S
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:908
Impact of a 3-Months Vegetarian Diet on the Gut Microbiota and Immune Repertoire
Zhang C; Bjorkman A; Cai K; Liu G; Wang C; Li Y; Xia H; Sun L; Kristiansen K; Wang J; Han J; Hammarstrom L; Pan-Hammarstrom Q
Article: MICROBIOLOGICAL RESEARCH. 2017;205:88-98
Characterization and complete genome sequences of L. rhamnosus DSM 14870 and L-gasseri DSM 14869 contained in the EcoVag® probiotic vaginal capsules
Marcotte H; Andersen KK; Lin Y; Zuo F; Zeng Z; Larsson PG; Brandsborg E; Bronstad G; Hammarstrom L
Article: MICROBIAL CELL FACTORIES. 2017;16(1):148
Lactobacillus delivery of bioactive interleukin-22
Lin Y; Krogh-Andersen K; Hammarstrom L; Marcotte H
Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2017;28(5):478-484
Clinical, immunologic, molecular analyses and outcomes of iranian patients with LRBA deficiency: A longitudinal study
Azizi G; Abolhassani H; Mahdaviani SA; Chavoshzadeh Z; Eshghi P; Yazdani R; Kiaee F; Shaghaghi M; Mohammadi J; Rezaei N; Hammarstrom L; Aghamohammadi A
Article: JOURNAL OF VIROLOGY. 2017;91(14):e00567-e00517
Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades
Sharma S; Carlsson B; Czako R; Vene S; Haglund M; Ludvigsson J; Larson G; Hammarstrom L; Sosnovtsev SV; Atmar RL; Green KY; Estes MK; Svensson L
Article: BMC IMMUNOLOGY. 2017;18(1):34
Autoantibodies against BAFF, APRIL or IL21-an alternative pathogenesis for antibody-deficiencies?
Pott M-C; Frede N; Wanders J; Hammarstrom L; Glocker E-O; Glocker C; Tahami F; Grimbacher B
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1293-1301.e4
Heterozygosity for transmembrane activator and calcium modulator ligand interactor A144E causes haploinsufficiency and pneumococcal susceptibility in mice
Jabara HH; Lee JJ; Janssen E; Ullas S; Liadaki K; Garibyan L; Benson H; Sannikova T; Bram R; Hammarstrom L; Cruz AC; Siegel R; Manis J; Malley R; Geha RS
Article: CLINICAL IMMUNOLOGY. 2017;176:71-76
NEIL1 is a candidate gene associated with common variable immunodeficiency in a patient with a chromosome 15q24 deletion
Romano R; Zaravinos A; Liadaki K; Caridha R; Lundin J; Carlsson G; Winiarski J; Pan-Hammarstrom Q; Hammarstrom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2017;37(1):51-60
Newborn Screening for Severe Primary Immunodeficiency Diseases in Sweden-a 2-Year Pilot TREC and KREC Screening Study
Barbaro M; Ohlsson A; Borte S; Jonsson S; Zetterstrom RH; King J; Winiarski J; von Dobeln U; Hammarstrom L
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2017;214(1):91-106
Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency
Abolhassani H; Edwards ESJ; Ikinciogullari A; Jing H; Borte S; Buggert M; Du L; Matsuda-Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson AC; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Su HC; Pan-Hammarstrom Q
Article: PLOS ONE. 2017;12(9):e0184748
Surge of immune cell formation at birth differs by mode of delivery and infant characteristics-A population-based cohort study
Schlinzig T; Johansson S; Stephansson O; Hammarstrom L; Zetterstrom RH; von Dobeln U; Cnattingius S; Norman M
Article: NATURE GENETICS. 2016;48(11):1425-1429
Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency
Bronson PG; Chang D; Bhangale T; Seldin MF; Ortmannl W; Ferreira RC; Urcelay E; Fernandez Pereira L; Martin J; Plebani A; Lougaris V; Friman V; Freiberger T; Litzman J; Thon V; Pan-Hammarstrom Q; Hammarstrom L; Graham RR; Behrens TW
Article: ZHONGGUO SHI YAN XUE YE XUE ZA ZHI / ZHONGGUO BING LI SHENG LI XUE HUI = JOURNAL OF EXPERIMENTAL HEMATOLOGY / CHINESE ASSOCIATION OF PATHOPHYSIOLOGY. 2016;24(4):1216-1220
[Study on immunoglobulin A Deficiency(IgAD) in Chinese Shanghai Blood Donors].
Lu P; Ling B; Wang N; Hammarstrom L
Article: SCIENTIFIC REPORTS. 2016;6:30171
Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus
Gunaydin G; Yu S; Graslund T; Hammarstrom L; Marcotte H
Article: NATURE GENETICS. 2016;48(7):740-746
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease
Zhou F; Cao H; Zuo X; Zhang T; Zhang X; Liu X; Xu R; Chen G; Zhang Y; Zheng X; Jin X; Gao J; Mei J; Sheng Y; Li Q; Liang B; Shen J; Shen C; Jiang H; Zhu C; Fan X; Xu F; Yue M; Yin X; Ye C; Zhang C; Liu X; Yu L; Wu J; Chen M; Zhuang X; Tang L; Shao H; Wu L; Li J; Xu Y; Zhang Y; Zhao S; Wang Y; Li G; Xu H; Zeng L; Wang J; Bai M; Chen Y; Chen W; Kang T; Wu Y; Xu X; Zhu Z; Cui Y; Wang Z; Yang C; Wang P; Xiang L; Chen X; Zhang A; Gao X; Zhang F; Xu J; Zheng M; Zheng J; Zhang J; Yu X; Li Y; Yang S; Yang H; Wang J; Liu J; Hammarstrom L; Sun L; Wang J; Zhang X
Article: JOURNAL OF IMMUNOLOGY. 2016;196(12):5138-5147
Multiple IgH Isotypes Including IgD, Subclasses of IgM, and IgY Are Expressed in the Common Ancestors of Modern Birds
Han B; Yuan H; Wang T; Li B; Ma L; Yu S; Huang T; Li Y; Fang D; Chen X; Wang Y; Qiu S; Guo Y; Fei J; Ren L; Pan-Hammarstrom Q; Hammarstrom L; Wang J; Wang J; Hou Y; Pan Q; Xu X; Zhao Y
Article: JOURNAL OF IMMUNOLOGY. 2016;196(10):4358-4366
Internal Duplications of DH, JH, and C Region Genes Create an Unusual IgH Gene Locus in Cattle
Ma L; Qin T; Chu D; Cheng X; Wang J; Wang X; Wang P; Han H; Ren L; Aitken R; Hammarstrom L; Li N; Zhao Y
Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2016;12(4):479-486
Cohort of Iranian Patients with Congenital Agammaglobulinemia: Mutation Analysis and Novel Gene Defects
Abolhassani H; Vitali M; Lougaris V; Giliani S; Parvaneh N; Parvaneh L; Mirminachi B; Cheraghi T; Khazaei H; Mahdaviani SA; Kiaei F; Tavakolinia N; Mohammadi J; Negahdari B; Rezaei N; Hammarstrom L; Plebani A; Aghamohammadi A
Article: MOLECULAR MEDICINE. 2016;21(1):769-781
Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations
Seldin MF; Alkhairy OK; Lee AT; Lamb JA; Sussman J; Pirskanen-Matell R; Piehl F; Verschuuren JJGM; Kostera-Pruszczyk A; Szczudlik P; Mckee D; Maniaol AH; Harbo HF; Lie BA; Melms A; Garchon H-J; Willcox N; Gregersen PK; Hammarstrom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2016;36(2):134-140
Risk of Infections Among 2100 Individuals with IgA Deficiency: a Nationwide Cohort Study
Ludvigsson JF; Neovius M; Hammarstrom L
Article: INFECTION AND IMMUNITY. 2016;84(2):395-406
Neutralization of Clostridium difficile Toxin B Mediated by Engineered Lactobacilli That Produce Single-Domain Antibodies
Andersen KK; Strokappe NM; Hultberg A; Truusalu K; Smidt I; Mikelsaar R-H; Mikelsaar M; Verrips T; Hammarstrom L; Marcotte H
Article: CELL HOST AND MICROBE. 2016;19(1):55-66
Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori
Moonens K; Gideonsson P; Subedi S; Bugaytsova J; Romao E; Mendez M; Norden J; Fallah M; Rakhimova L; Shevtsova A; Lahmann M; Castaldo G; Brannstrom K; Coppens F; Lo AW; Ny T; Solnick JV; Vandenbussche G; Oscarson S; Hammarstrom L; Arnqvist A; Berg DE; Muyldermans S; Boren T; Remaut H
Article: VIRUS RESEARCH. 2016;211:64-68
Association of elevated rotavirus-specific antibody titers with HBGA secretor status in Swedish individuals: The FUT2 gene as a putative susceptibility determinant for infection
Gunaydin G; Nordgren J; Sharm S; Hammarstrom L
Article: PLOS ONE. 2016;11(9):e0162733
Oral Delivery of Pentameric Glucagon-Like Peptide-1 by Recombinant Lactobacillus in Diabetic Rats
Lin Y; Krogh-Andersen K; Pelletier J; Marcotte H; Ostenson C-G; Hammarstrom L
Article: HUMAN MOLECULAR GENETICS. 2015;24(25):7361-7372
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency
Volk T; Pannicke U; Reisli I; Bulashevska A; Ritter J; Bjorkman A; Schaeffer AA; Fliegauf M; Sayar EH; Salzer U; Fisch P; Pfeifer D; Di Virgilio M; Cao H; Yang F; Zimmermann K; Keles S; Caliskaner Z; Guner S; Schindler D; Hammarstroem L; Rizzi M; Hummel M; Pan-Hammarstrom Q; Schwarz K; Grimbacher B
Article: JOURNAL OF IMMUNOLOGY. 2015;195(12):5608-5615
DNA-PKcs Is Involved in Ig Class Switch Recombination in Human B Cells
Bjorkman A; Du L; Felgentreff K; Rosner C; Kamdar RP; Kokaraki G; Matsumoto Y; Davies EG; van der Burg M; Notarangelo LD; Hammarstrom L; Pan-Hammarstrom Q
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2015;212(10):1641-1662
Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome
Kreins AY; Ciancanelli MJ; Okada S; Kong X-F; Ramirez-Alejo N; Kilic SS; El Baghdadi J; Nonoyama S; Mahdaviani SA; Ailal F; Bousfiha A; Mansouri D; Nievas E; Ma CS; Rao G; Bernasconi A; Kuehn HS; Niemela J; Stoddard J; Deveau P; Cobat A; El Azbaoui S; Sabri A; Lim CK; Sundin M; Avery DT; Halwani R; Grant AV; Boisson B; Bogunovic D; Itan Y; Moncada-Velez M; Martinez-Barricarte R; Migaud M; Deswarte C; Alsina L; Kotlarz D; Klein C; Muller-Fleckenstein I; Fleckenstein B; Cormier-Daire V; Rose-John S; Picard C; Hammarstrom L; Puel A; Al-Muhsen S; Abel L; Chaussabel D; Rosenzweig SD; Minegishi Y; Tangye SG; Bustamante J; Casanova J-L; Boisson-Dupuis S
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;136(3):703-712.e10
Novel mutations in TNFRSF7/CD27: Clinical, immunologic, and genetic characterization of human CD27 deficiency
Alkhairy OK; Perez-Becker R; Driessen GJ; Abolhassani H; van Montfrans J; Borte S; Choo S; Wang N; Tesselaar K; Fang M; Bienemann K; Boztug K; Daneva A; Mechinaud F; Wiesel T; Becker C; Duckers G; Siepermann K; van Zelm MC; Rezaei N; van der Burg M; Aghamohammadi A; Seidel MG; Niehues T; Hammarstrom L
Article: APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2015;81(17):5784-5793
An Exopolysaccharide-Deficient Mutant of Lactobacillus rhamnosus GG Efficiently Displays a Protective Llama Antibody Fragment against Rotavirus on Its Surface
Alvarez B; Krogh-Andersen K; Tellgren-Roth C; Martinez N; Guenaydin G; Lin Y; Cruz Martin M; Alvarez MA; Hammarstroem L; Marcotte H
Article: JOURNAL OF PROTEOMICS. 2015;126:155-162
Heat differentiated complement factor profiling
Hamsten C; Skattum L; Truedsson L; von Dobeln U; Uhlen M; Schwenk JM; Hammarstrom L; Nilsson P; Neiman M
Article: IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY. 2015;14(4):457-461
A New IL-2RG Gene Mutation in an X-linked SCID Identified through TREC/KREC Screening: a Case Report
Nourizadeh M; Borte S; Fazlollahi MR; Hammarstrom L; Pourpak Z
Article: BMC INFECTIOUS DISEASES. 2015;15:255
Vaginal colonisation by probiotic lactobacilli and clinical outcome in women conventionally treated for bacterial vaginosis and yeast infection
Pendharkar S; Brandsborg E; Hammarstrom L; Marcotte H; Larsson P-G
Article: JOURNAL OF INTERNAL MEDICINE. 2015;277(5):594-604
The autoimmune spectrum of myasthenia gravis: a Swedish population-based study
Fang F; Sveinsson O; Thormar G; Granqvist M; Askling J; Lundberg IE; Ye W; Hammarstrom L; Pirskanen R; Piehl F
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2015;50(1):26-28
IgA deficiency in wolves from Canada and Scandinavia
Frankowiack M; Olsson M; Cluff HD; Evans AL; Hellman L; Mansson J; Arnemo JM; Hammarstrom L
Article: NATURE COMMUNICATIONS. 2015;6:6804
Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
Li J; Jorgensen SF; Maggadottir SM; Bakay M; Warnatz K; Glessner J; Pandey R; Salzer U; Schmidt RE; Perez E; Resnick E; Goldacker S; Buchta M; Witte T; Padyukov L; Videm V; Folseraas T; Atschekzei F; Elder JT; Nair RP; Winkelmann J; Gieger C; Noethen MM; Buening C; Brand S; Sullivan KE; Orange JS; Fevang B; Schreiber S; Lieb W; Aukrust P; Chapel H; Cunningham-Rundles C; Franke A; Karlsen TH; Grimbacher B; Hakonarson H; Hammarstroem L; Ellinghaus E
Article: GENES AND IMMUNITY. 2015;16(3):199-205
The higher frequency of IgA deficiency among Swedish twins is not explained by HLA haplotypes
Frankowiack M; Kovanen R-M; Repasky GA; Lim CK; Song C; Pedersen NL; Hammarstom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2015;35(2):182-188
IgA Deficiency and Risk of Cancer: A Population-Based Matched Cohort Study
Ludvigsson JF; Neovius M; Ye W; Hammarstrom L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins
Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarstrom L; Malmstrom V; Askling J; Klareskog L; Catrina AI
Article: PLOS ONE. 2015;10(7):e0133844
Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency
Olsson M; Tengvall K; Frankowiack M; Kierczak M; Bergvall K; Axelsson E; Tintle L; Marti E; Roosje P; Leeb T; Hedhammar A; Hammarstrom L; Lindblad-Toh K
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2015;35(1):87-91
Reversal of Immunoglobulin A Deficiency in Children
Lim CK; Dahle C; Elvin K; Andersson BA; Ronnelid J; Melen E; Bergstrom A; Truedsson L; Hammarstrom L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;178(Suppl 1):14-15
Primary immunodeficiencies screening: neonatal screening for T/B cell disorders - a triplex PCR method for quantitation of TRECs and KRECs in newborns
Hammarstrom L
Article: CLINICAL INFECTIOUS DISEASES. 2014;59(11):1567-1573
Both Lewis and Secretor Status Mediate Susceptibility to Rotavirus Infections in a Rotavirus Genotype-Dependent Manner
Nordgren J; Sharma S; Bucardo F; Nasir W; Gunaydin G; Ouermi D; Nitiema LW; Becker-Dreps S; Simpore J; Hammarstrom L; Larson G; Svensson L
Article: CLINICAL IMMUNOLOGY. 2014;155(1):74-78
Newborn screening for severe T and B cell lymphopenia identifies a fraction of patients with Wiskott-Aldrich syndrome
Borte S; Fasth A; von Dobeln U; Winiarski J; Hammarstrom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(7):853-863
IgA Deficiency, Autoimmunity & Pregnancy: A Population-Based Matched Cohort Study
Ludvigsson JF; Neovius M; Stephansson O; Hammarstrom L
Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2014;10(10):1405-1417
Long-term evaluation of a historical cohort of Iranian common variable immunodeficiency patients
Aghamohammadi A; Abolhassani H; Latif A; Tabassomi F; Shokuhfar T; Sagvand BT; Shahinpour S; Mirminachi B; Parvaneh N; Movahedi M; Gharagozlou M; Sherkat R; Amin R; Aleyasin S; Faridhosseini R; Jabbari-Azad F; Cheraghi T; Eslamian MH; Khalili A; Kalantari N; Shafiei A; Dabbaghzade A; Khayatzadeh A; Ebrahimi M; Razavinejad D; Bazregari S; Ebrahimi M; Ghaffari J; Bemanian MH; Behniafard N; Kashef S; Mohammadzadeh I; Hammarstrom L; Rezaei N
Article: CLINICAL IMMUNOLOGY. 2014;154(2):105-111
Novel NLRP12 mutations associated with intestinal amyloidosis in a patient diagnosed with common variable immunodeficiency
Borte S; Celiksoy MH; Menzel V; Ozkaya O; Ozen FZ; Hammarstroem L; Yildiran A
Article: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 2014;160(3-4):255-259
The dog as a genetic model for immunoglobulin A (IgA) deficiency: Identification of several breeds with low serum IgA concentrations
Olsson M; Frankowiack M; Tengvall K; Roosje P; Fall T; Ivansson E; Bergvall K; Hansson-Hamlin H; Sundberg K; Hedhammar A; Lindblad-Toh K; Hammarstrom L
Article: HUMAN MOLECULAR GENETICS. 2014;23(15):4177-4184
IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L
Viktorin A; Frankowiack M; Padyukov L; Chang Z; Melen E; Saaf A; Kull I; Klareskog L; Hammarstrom L; Magnusson PKE
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(5):573-583
Reduced BAFF-R and Increased TACI Expression in Common Variable Immunodeficiency
Barbosa RR; Silva SL; Silva SP; Melo AC; Conceicao Pereira-Santos M; Barata JT; Hammarstrom L; Cascalho M; Sousa AE
Article: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. 2014;78(7):1153-1157
Normalized immunoglobulin patterns in adults with recurrent acute otitis media and low IgG2 levels during early childhood
Krakau M; Dagoo BR; Hammarstrom L; Granath A
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(4):514-519
Retrospective Analysis of TREC Based Newborn Screening Results and Clinical Phenotypes in Infants with the 22q11 Deletion Syndrome
Framme JL; Borte S; von Doebeln U; Hammarstrm L; Oskarsdttir S
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(4):444-451
Association Between IgA Deficiency & Other Autoimmune Conditions: A Population-Based Matched Cohort Study
Ludvigsson JF; Neovius M; Hammarstrom L
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2014;21(3):298-301
Mutations in Toll-Like Receptor 3 Are Associated with Elevated Levels of Rotavirus-Specific IgG Antibodies in IgA-Deficient but Not IgA-Sufficient Individuals
Gunaydin G; Nordgren J; Svensson L; Hammarstrom L
Article: QUALITY OF LIFE RESEARCH. 2014;23(2):645-658
Health-related quality of life (HRQL) in immunodeficient adults with selective IgA deficiency compared with age- and gender-matched controls and identification of risk factors for poor HRQL
Jorgensen GH; Gardulf A; Sigurdsson MI; Arnlaugsson S; Hammarstrom L; Ludviksson BR
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(2):157-162
Caucasian Origin of Disease Associated HLA Haplotypes in Chinese Blood Donors with IgA Deficiency
Wang N; Lu P; Ling B; Zhu Z; Hammarstrom L
Article: VACCINE. 2014;32(4):470-477
Engineered Lactobacillus rhamnosus GG expressing IgG-binding domains of protein G: Capture of hyperimmune bovine colostrum antibodies and protection against diarrhea in a mouse pup rotavirus infection model
Gunaydin G; Zhang R; Hammarstroem L; Marcotte H
Article: PLOS ONE. 2014;9(4):e96409
Co-Expression of Anti-Rotavirus Proteins (Llama VHH Antibody Fragments) in Lactobacillus: Development and Functionality of Vectors Containing Two Expression Cassettes in Tandem
Gunaydin G; Alvarez B; Lin Y; Hammarstroem L; Marcotte H
Article: PLOS ONE. 2014;9(4):e93180
Serological Assessment for Celiac Disease in IgA Deficient Adults
Wang N; Truedsson L; Elvin K; Andersson BA; Ronnelid J; Mincheva-Nilsson L; Lindkvist A; Ludvigsson JF; Hammarstrom L; Dahle C
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2013;210(12):2503-2513
A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination
Enervald E; Du L; Visnes T; Bojrkman A; Lindgren E; Wincent J; Borck G; Colleaux L; Cormier-Daire V; van Gent DC; Pie J; Puisac B; de Miranda NFCC; Kracker S; Hammarstrom L; de Villartay J-P; Durandy A; Schoumans J; Strom L; Pan-Hammarstrom Q
Article: MABS. 2013;5(6):860-871
NFκB induces overexpression of bovine FcRn A novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn
Cervenak J; Doleschall M; Bender B; Mayer B; Schneider Z; Doleschall Z; Zhao Y; Bosze Z; Hammarstrom L; Oster W; Kacskovics I
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2013;33(8):1317-1324
IgA Deficiency & Mortality: A Population-Based Cohort Study
Ludvigsson JF; Neovius M; Hammarstrom L
Article: GASTROENTEROLOGY. 2013;145(4):740-748.e8
Anti-Rotavirus Protein Reduces Stool Output in Infants With Diarrhea: A Randomized Placebo-Controlled Trial
Sarker SA; Jakel M; Sultana S; Alam NH; Bardhan PK; Chisti MJ; Salam MA; Theis W; Hammarstrom L; Frenken LGJ
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2013;33(6):1078-1087
A Phenotypic Approach for IUIS PID Classification and Diagnosis: Guidelines for Clinicians at the Bedside
Aziz Bousfiha A; Jeddane L; Ailal F; Al Herz W; Conley ME; Cunningham-Rundles C; Etzioni A; Fischer A; Luis Franco J; Geha RS; Hammarstrom L; Nonoyama S; Ochs HD; Roifman CM; Seger R; Tang MLK; Puck JM; Chapel H; Notarangelo LD; Casanova J-L
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2013;40(2):180-184
IgA deficiency in wolves
Frankowiack M; Hellman L; Zhao Y; Arnemo JM; Lin M; Tengvall K; Moller T; Lindblad-Toh K; Hammarstrom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2013;33(4):742-747
Clinical Symptoms in Adults with Selective IgA Deficiency: A Case-Control Study
Jorgensen GH; Gardulf A; Sigurdsson MI; Sigurdardottir ST; Thorsteinsdottir I; Gudmundsson S; Hammarstrom L; Ludviksson BR
Article: PLOS GENETICS. 2013;9(5):e1003475
Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
Tengvall K; Kierczak M; Bergvall K; Olsson M; Frankowiack M; Farias FHG; Pielberg G; Carlborg O; Leeb T; Andersson G; Hammarstrom L; Hedhammar A; Lindblad-Toh K
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;172(1):63-72
Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients
Wong GK; Goldacker S; Winterhalter C; Grimbacher B; Chapel H; Lucas M; Alecsandru D; McEwen D; Quinti I; Martini H; Milito C; Schmidt RE; Ernst D; Espanol T; Vidaller A; Carbone J; Fernandez-Cruz E; Lougaris V; Plebani A; Kutukculer N; Gonzalez-Granado LI; Contreras R; Kiani-Alikhan S; Ibrahim MAA; Litzman J; Jones A; Gaspar HB; Hammarstrom L; Baumann U; Warnatz K; Huissoon AP
Article: BMC INFECTIOUS DISEASES. 2013;13:43
Identification and characterisation of vaginal lactobacilli from South African women
Pendharkar S; Magopane T; Larsson P-G; de Bruyn G; Gray GE; Hammarstrom L; Marcotte H
Article: NATURE COMMUNICATIONS. 2013;4:1337
Extensive diversification of IgH subclass-encoding genes and IgM subclass switching in crocodilians
Cheng G; Gao Y; Wang T; Sun Y; Wei Z; Li L; Ren L; Guo Y; Hu X; Lu Y; Wang X; Liu G; Zhang C; Yu J; Pan-Hammarstrom Q; Hammarstrom L; Wu X; Li N; Zhao Y
Article: ANNALS OF NEUROLOGY. 2012;72(6):927-935
Risk for Myasthenia Gravis Maps to a ¹⁵¹Pro→Ala Change in TNIP1 and to Human Leukocyte Antigen-B*08
Gregersen PK; Kosoy R; Lee AT; Lamb J; Sussman J; McKee D; Simpfendorfer KR; Pirskanen-Matell R; Piehl F; Pan-Hammarstrom Q; Verschuuren JJGM; Titulaer MJ; Niks EH; Marx A; Stroebel P; Tackenberg B; Puetz M; Maniaol A; Elsais A; Tallaksen C; Harbo HF; Lie BA; Raychaudhuri S; de Bakker PIW; Melms A; Garchon H-J; Willcox N; Hammarstrom L; Seldin MF
Article: JOURNAL OF IMMUNOLOGY. 2012;189(8):3995-4004
Extensive Diversification of IgD-, IgY-, and Truncated IgY(ΔFc)-Encoding Genes in the Red-Eared Turtle (Trachemys scripta elegans)
Li L; Wang T; Sun Y; Cheng G; Yang H; Wei Z; Wang P; Hu X; Ren L; Meng Q; Zhang R; Guo Y; Hammarstrom L; Li N; Zhao Y
Article: JOURNAL OF IMMUNOLOGY. 2012;189(7):3557-3565
Evidence of IgY Subclass Diversification in Snakes: Evolutionary Implications
Wang T; Sun Y; Shao W; Cheng G; Li L; Cao Z; Yang Z; Zou H; Zhang W; Han B; Hu Y; Ren L; Hu X; Guo Y; Fei J; Hammarstrom L; Li N; Zhao Y
Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2012;8(6):539-546
Novel mutation of the activation-induced cytidine deaminase gene in a Tajik family: special review on hyper-immunoglobulin M syndrome
Mahdaviani SA; Hirbod-Mobarakeh A; Wang N; Aghamohammadi A; Hammarstrom L; Masjedi MR; Pan-Hammarstrom Q; Rezaei N
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;90(6):986-1001
Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity
Lopez-Herrera G; Tampella G; Pan-Hammarstrom Q; Herholz P; Trujillo-Vargas CM; Phadwal K; Simon AK; Moutschen M; Etzioni A; Mory A; Srugo I; Melamed D; Hultenby K; Liu C; Baronio M; Vitali M; Philippet P; Dideberg V; Aghamohammadi A; Rezaei N; Enright V; Du L; Salzer U; Eibel H; Pfeifer D; Veelken H; Stauss H; Lougaris V; Plebani A; Gertz EM; Schaeffer AA; Hammarstrom L; Grimbacher B
Article: GENES AND IMMUNITY. 2012;13(1):59-65
Rare mutations in TNFRSF13B increase the risk of asthma symptoms in Swedish children
Janzi M; Melen E; Kull I; Wickman M; Hammarstrom L
Article: PLOS GENETICS. 2012;8(1):e1002476
High-Density SNP Mapping of the HLA Region Identifies Multiple Independent Susceptibility Loci Associated with Selective IgA Deficiency
Ferreira RC; Pan-Hammarstrom Q; Graham RR; Fontan G; Lee AT; Ortmann W; Wang N; Urcelay E; Fernandez-Arquero M; Nunez C; Jorgensen G; Ludviksson BR; Koskinen S; Haimila K; Padyukov L; Gregersen PK; Hammarstrom L; Behrens TW
Article: PLOS ONE. 2012;7(8):e43419
Placental Transfer of Maternally-Derived IgA Precludes the Use of Guthrie Card Eluates as a Screening Tool for Primary Immunodeficiency Diseases
Borte S; Janzi M; Pan-Hammarstrom Q; von Dobeln U; Nordvall L; Winiarski J; Fasth A; Hammarstrom L
Article: PLOS ONE. 2012;7(3):e34346
Analysis of Immunoglobulin Transcripts in the Ostrich Struthio camelus, a Primitive Avian Species
Huang T; Zhang M; Wei Z; Wang P; Sun Y; Hu X; Ren L; Meng Q; Zhang R; Guo Y; Hammarstrom L; Li N; Zhao Y
Article: BMC BIOTECHNOLOGY. 2011;11:126
In situ gastrointestinal protection against anthrax edema toxin by single-chain antibody fragment producing lactobacilli
Andersen KK; Marcotte H; Alvarez B; Boyaka PN; Hammarstrom L
Article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2011;1246:118-130
Newborn screening for primary immunodeficiencies: beyond SCID and XLA
Borte S; Wang N; Oskarsdottir S; von Dobeln U; Hammarstrom L
Article: THE FEBS JOURNAL. 2011;278(19):3769-3781
Alteration of the N-glycome of bovine milk glycoproteins during early lactation
Takimori S; Shimaoka H; Furukawa J-I; Yamashita T; Amano M; Fujitani N; Takegawa Y; Hammarstrom L; Kacskovics I; Shinohara Y; Nishimura S-I
Article: BMC INFECTIOUS DISEASES. 2011;11:223
Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses
Larsson P-G; Brandsborg E; Forsum U; Pendharkar S; Andersen KK; Nasic S; Hammarstrom L; Marcotte H
Article: JOURNAL OF NEUROIMMUNOLOGY. 2011;236(1-2):118-122
Concomitant autoimmunity in myasthenia gravis - Lack of association with IgA deficiency
Ramanujam R; Piehl F; Pirskanen R; Gregersen PK; Hammarstrom L
Article: FUTURE MICROBIOLOGY. 2011;6(5):583-593
Lactobacilli producing bispecific llama-derived anti-rotavirus proteins in vivo for rotavirus-induced diarrhea
Pant N; Marcotte H; Hermans P; Bezemer S; Frenken L; Johansen K; Hammarstrom L
Article: TWIN RESEARCH AND HUMAN GENETICS. 2011;14(2):129-136
Utilizing Twins Concordance Rates to Infer the Predisposition to Myasthenia Gravis
Ramanujam R; Pirskanen R; Ramanujam S; Hammarstrom L
Article: APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2011;77(6):2174-2179
Integrative Expression System for Delivery of Antibody Fragments by Lactobacilli
Cruz Martin M; Pant N; Ladero V; Gunaydin G; Andersen KK; Alvarez B; Martinez N; Alvarez MA; Hammarstrom L; Marcotte H
Article: HUMAN IMMUNOLOGY. 2011;72(2):166-172
Association of immunoglobulin A deficiency and elevated thyrotropin-receptor autoantibodies in two Nordic countries
Jorgensen GH; Ornolfsson AE; Johannesson A; Gudmundsson S; Janzi M; Wang N; Hammarstrom L; Ludviksson BR
Article: CURRENT MICROBIOLOGY. 2010;61(6):560-566
Screening and Evaluation of Human Intestinal Lactobacilli for the Development of Novel Gastrointestinal Probiotics
Koll P; Maendar R; Smidt I; Huett P; Truusalu K; Mikelsaar R-H; Shchepetova J; Krogh-Andersen K; Marcotte H; Hammarstrom L; Mikelsaar M
Article: BMC RESEARCH NOTES. 2010;3:292
The CD45 77C/G allele is not associated with myasthenia gravis - a reassessment of the potential role of CD45 in autoimmunity.
Ramanujam R; Pirskanen R; Hammarström L
Article: BMC MEDICAL GENETICS. 2010;11:147
Lack of association of the CIITA-168A→G promoter SNP with myasthenia gravis and its role in autoimmunity
Ramanujam R; Zhao Y; Pirskanen R; Hammarstrom L
Article: PLOS ONE. 2010;5(8):e12260
Unique DNA Repair Gene Variations and Potential Associations with the Primary Antibody Deficiency Syndromes IgAD and CVID
Offer SM; Pan-Hammarstrom Q; Hammarstrom L; Harris RS
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2010;34(5):579-589
Phylogeny, genomic organization and expression of λ and κ immunoglobulin light chain genes in a reptile, Anolis carolinensis
Wu Q; Wei Z; Yang Z; Wang T; Ren L; Hu X; Meng Q; Guo Y; Zhu Q; Robert J; Hammarstrom L; Li N; Zhao Y
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;125(2):424-432.e8
Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome
Woellner C; Gertz EM; Schaeffer AA; Lagos M; Perro M; Glocker E-O; Pietrogrande MC; Cossu F; Franco JL; Matamoros N; Pietrucha B; Heropolitanska-Pliszka E; Yeganeh M; Moin M; Espanol T; Ehl S; Gennery AR; Abinun M; Breborowicz A; Niehues T; Kilic SS; Junker A; Turvey SE; Plebani A; Sanchez B; Garty B-Z; Pignata C; Cancrini C; Litzman J; Sanal O; Baumann U; Bacchetta R; Hsu AP; Davis JN; Hammarstroem L; Davies EG; Eren E; Arkwright PD; Moilanen JS; Viemann D; Khan S; Laszlo M; Cant AJ; Freeman AF; Puck JM; Holland SM; Grimbacher B
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2010;30(1):138-143
IgA Deficiency and the MHC: Assessment of Relative Risk and Microheterogeneity Within the HLA A1 B8, DR3 (8.1) Haplotype
Mohammadi J; Ramanujam R; Jarefors S; Rezaei N; Aghamohammadi A; Gregersen PK; Hammarstrom L
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2009;124(6):1161-1178
Primary immunodeficiencies: 2009 update
Notarangelo LD; Fischer A; Geha RS; Casanova J-L; Chapel H; Conley ME; Cunningham-Rundles C; Etzioni A; Hammartrom L; Nonoyama S; Ochs HD; Puck J; Roifman C; Seger R; Wedgwood J
Article: BLOOD. 2009;114(19):4089-4098
Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency
Borte S; Pan-Hammarstrom Q; Liu C; Sack U; Borte M; Wagner U; Graf D; Hammarstrom L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18680-18685
Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
Rioux JD; Goyette P; Vyse TJ; Hammarstroem L; Fernando MMA; Green T; De Jager PL; Foisy S; Wang J; de Bakker PIW; Leslie S; McVean G; Padyukov L; Alfredsson L; Annese V; Hafler DA; Pan-Hammarstroem Q; Matell R; Sawcer SJ; Compston AD; Cree BAC; Mirel DB; Daly MJ; Behrens TW; Klareskog L; Gregersen PK; Oksenberg JR; Hauser SL
Article: MOLECULAR MEDICINE. 2009;15(11-12):371-383
European Population Genetic Substructure: Further Definition of Ancestry Informative Markers for Distinguishing among Diverse European Ethnic Groups
Tian C; Kosoy R; Nassir R; Lee A; Villoslada P; Klareskog L; Hammarstrom L; Garchon H-J; Pulver AE; Ransom M; Gregersen PK; Seldin MF
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2009;29(6):777-785
Novel Mutations in TACI (TNFRSF13B) Causing Common Variable Immunodeficiency
Mohammadi J; Liu C; Aghamohammadi A; Bergbreiter A; Du L; Lu J; Rezaei N; Amirzargar AA; Moin M; Salzer U; Pan-Hammarstrom Q; Hammarstrom L
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2009;29(6):769-776
Clinical and Laboratory Findings in Hyper-IgM Syndrome with Novel CD40L and AICDA Mutations
Aghamohammadi A; Parvaneh N; Rezaei N; Moazzami K; Kashef S; Abolhassani H; Imanzadeh A; Mohammadi J; Hammarstrom L
Article: JOURNAL OF NEUROIMMUNOLOGY. 2009;215(1-2):122-124
Does IgG therapy prevent Alzheimer's disease?
Hammarstrom L; Hansen S; Gardulf A
Article: ANIMAL BIOTECHNOLOGY. 2009;20(4):242-246
ASSOCIATION OF FcRn HEAVY CHAIN ENCODING GENE (FCGRT) POLYMORPHISMS WITH IgG CONTENT IN BOVINE COLOSTRUM
Zhang R; Zhao Z; Zhao Y; Kacskovics I; van der Eijk M; de Groot N; Li N; Hammarstrom L
Article: CLINICAL IMMUNOLOGY. 2009;133(1):78-85
Selective IgA deficiency in early life: Association to infections and allergic diseases during childhood
Janzi M; Kull I; Sjoberg R; Wan J; Melen E; Bayat N; Ostblom E; Pan-Hammarstrom Q; Nilsson P; Hammarstrom L
Article: JOURNAL OF IMMUNOLOGY. 2009;183(6):3858-3864
Expression of IgM, IgD, and IgY in a Reptile, Anolis carolinensis
Wei Z; Wu Q; Ren L; Hu X; Guo Y; Warr GW; Hammarstrom L; Li N; Zhao Y
Article: JOURNAL OF IMMUNOLOGY. 2009;183(5):3285-3293
Ornithorhynchus anatinus (Platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Nonmammalian Tetrapods
Zhao Y; Cui H; Whittington CM; Wei Z; Zhang X; Zhang Z; Yu L; Ren L; Hu X; Zhang Y; Hellman L; Belov K; Li N; Hammarstrom L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(33):13945-13950
B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans
Warnatz K; Salzer U; Rizzi M; Fischer B; Gutenberger S; Boehm J; Kienzler A-K; Pan-Hammarstroem Q; Hammarstroem L; Rakhmanov M; Schlesier M; Grimbacher B; Peter H-H; Eibel H
Article: CLINICAL IMMUNOLOGY. 2009;131(2):233-239
Familial aggregation of IgAD and autoimmunity
Jorgensen GH; Thorsteinsdottir I; Gudmundsson S; Hammarstrom L; Ludviksson BR
Article: AVICENNA JOURNAL OF MEDICAL BIOTECHNOLOGY. 2009;1(1):37-39
Construction of a High Efficiency PCR Products Cloning T Vector Using pGEM-5zf (+).
Zhao Y; Liu Z; Yu S; Wen S; Hammarstrom L; Rabbani H
Article: GENES AND IMMUNITY. 2009;10(2):151-161
The shared CTLA4-ICOS risk locus in celiac disease, IgA deficiency and common variable immunodeficiency
Haimila K; Einarsdottir E; de Kauwe A; Koskinen LLE; Pan-Hammarstrom Q; Kaartinen T; Kurppa K; Ziberna F; Not T; Vatta S; Ventura A; Korponay-Szabo IR; Adany R; Poscai Z; Szeles G; Dukes E; Kaukinen K; Maki M; Koskinen S; Partanen J; Hammarstrom L; Saavalainen P
Article: BLOOD. 2009;113(9):1967-1976
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes
Salzer U; Bacchelli C; Buckridge S; Pan-Hammarstrom Q; Jennings S; Lougaris V; Bergbreiter A; Hagena T; Birmelin J; Plebani A; Webster ADB; Peter H-H; Suez D; Chapel H; McLean-Tooke A; Spickett GP; Anover-Sombke S; Ochs HD; Urschel S; Belohradsky BH; Ugrinovic S; Kumararatne DS; Lawrence TC; Holm AM; Franco JL; Schulze I; Schneider P; Gertz EM; Schaffer AA; Hammarstrom L; Thrasher AJ; Gaspar HB; Grimbacher B
Article: GLYCOBIOLOGY. 2009;19(2):182-191
Novel Le^b-like Helicobacter pylori-binding glycosphingolipid created by the expression of human α-1,3/4-fucosyltransferase in FVB/N mouse stomach
Fagerberg D; Angstrom J; Halim A; Hultberg A; Rakhimova L; Hammarstrom L; Boren T; Teneberg S
Article: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2009;19(3):233-236
Isolated Growth Hormone Deficiency in a Patient with Immunoglobulin Class Switch Recombination Deficiency
Kashef S; Ghaedian MM; Rezaei N; Karamizadeh Z; Aghamohammadi A; Durandy A; Pan-Hammarstrom Q; Hammarstrom L
Article: PLOS ONE. 2009;4(4):e5321
Screening for C3 Deficiency in Newborns Using Microarrays
Janzi M; Sjoberg R; Wan J; Fischler B; von Dobeln U; Isaac L; Nilsson P; Hammarstrom L
Article: IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY. 2008;7(4):209-214
Human Leukocyte Antigens (HLA) Associated with Selective IgA Deficiency in Iran and Sweden
Mohammadi J; Pourpak Z; Jarefors S; Saghafi S; Zendehdel K; Pourfathollah AA; Amirzargar AA; Aghamohammadi A; Moin M; Hammarstrom L
Article: MOLECULAR IMMUNOLOGY. 2008;46(1):202-206
Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients from different ethnic groups
Jiao H; Toth B; Erdos M; Fransson I; Rakoczi E; Balogh I; Magyarics Z; Derfalvi B; Csorba G; Szaflarska A; Megarbane A; Akatcherian C; Dbaibo G; Rajnavoelgyi E; Hammarstrom L; Kere J; Lefranc G; Marodi L
Article: CLINICAL IMMUNOLOGY. 2008;128(2):190-198
Restricted immunoglobulin constant heavy G chain genes in primary immunodeficiencies.
Oxelius V-A; Ochs HD; Hammarström L
Article: JOURNAL OF NEUROIMMUNOLOGY. 2008;197(2):110-113
PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis
Lefvert AK; Zhao Y; Ramanujam R; Yu S; Pirskanen R; Hammarstrom L
Article: BLOOD. 2008;112(2):277-286
Common variable immunodeficiency disorders: division into distinct clinical phenotypes
Chapel H; Lucas M; Lee M; Bjorkander J; Webster D; Grimbacher B; Fieschi C; Thon V; Abedi MR; Hammarstrom L
Article: FUTURE VIROLOGY. 2008;3(4):327-341
Engineered lactobody-producing lactobacilli:: a novel form of therapy against rotavirus infection
Marcotte H; Pant N; Hammarstrom L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;99(2):211-215
Linkage of IgA deficiency to Gm allotypes; the influence of Gm allotypes on IgA-IgG subclass deficiency.
Oxelius VA; Carlsson AM; Hammarström L; Björkander J; Hanson LA
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;152(2):274-279
Rapid subcutaneous immunoglobulin administration every second week results in high and stable serum immunoglobulin G levels in patients with primary antibody deficiencies
Gustafson R; Gardulf A; Hansen S; Leibl H; Engl W; Linden M; Mueller A; Hammarstrom L
Article: JOURNAL OF MEDICAL VIROLOGY. 2008;80(3):531-535
Individuals with selective IgA deficiency resolve rotavirus disease and develop higher antibody titers (IgG, IgG1) than IgA competent individuals
Istrate C; Hinkula J; Hammarstroem L; Svensson L
Article: IRANIAN JOURNAL OF ALLERGY, ASTHMA AND IMMUNOLOGY. 2008;7(1):41-44
Onychomadesis in a patient with immunoglobulin class switch recombination deficiency
Safari M; Rezaei N; Hajilooi M; Aghamohammadi A; Pan-Hammarstrom Q; Hammarstrom L
Article: SCANDINAVIAN JOURNAL OF LABORATORY ANIMAL SCIENCE. 2008;35(1):13-24
Helicobacter ganmani infection associated with a spontaneous outbreak of inflammatory bowel-like disease in an IL-10-deficient mouse colony
Nilsson I; Sturegard E; Barup B; Willen R; Abu Al-Soud W; Hultberg A; Hammarstrom L; Nilsson H-O; Wadstrom T
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2008;32(2):156-165
Genomic organization of the immunoglobulin light chain gene loci in Xenopus tropicalis:: Evolutionary implications
Qin T; Ren L; Hu X; Guo Y; Fei J; Zhu Q; Butler JE; Wu C; Li N; Hammarstrom L; Zhao Y
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2008;147(3):255-259
Severe Congenital Neutropenia or Hyper-IgM Syndrome? A Novel Mutation of CD40 Ligand in a Patient with Severe Neutropenia
Rezaei N; Aghamohammadi A; Ramyar A; Pan-Hammarstrom Q; Hammarstrom L
Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2008;606:321-343
Targeted antibodies in dairy-based products
Hammarstroem L; Weiner CK
Article: JOURNAL OF HEALTH, POPULATION AND NUTRITION. 2007;25(4):465-468
Successful treatment of rotavirus-induced diarrhoea in suckling mice with egg yolk immunoglobulin
Sarker SA; Pant N; Juneja LR; Hammarstrom L
Article: IMMUNOLOGY. 2007;122(3):401-408
Over-expression of the bovine FcRn in the mammary gland results in increased IgG levels in both milk and serum of transgenic mice
Lu W; Zhao Z; Zhao Y; Yu S; Zhao Y; Fan B; Kacskovics I; Hammarstroem L; Li N
Article: BMC MICROBIOLOGY. 2007;7:86
Effective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodies
Pant N; Marcotte H; Bruessow H; Svensson L; Hammarstrom L
Article: BMC BIOTECHNOLOGY. 2007;7:58
Lactobacillli expressing llama VHH fragments neutralise Lactococcus phages
Hultberg A; Tremblay DM; de Haard H; Verrips T; Moineau S; Hammarstoem L; Marcotte H
Article: TRANSGENIC RESEARCH. 2007;16(5):613-627
Position independent and copy-number-related expression of the bovine neonatal Fc receptor α-chain in transgenic mice carrying a 102 kb BAC genomic fragment
Bender B; Bodrogi L; Mayer B; Schneider Z; Zhao Y; Hammarstroem L; Eggen A; Kacskovics I; Bosze Z
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(17):7193-7198
Role for Msh5 in the regulation of Ig class switch recombination
Sekine H; Ferreira RC; Pan-Hammarstrom Q; Graham RR; Ziemba B; de Vries SS; Liu J; Hippen K; Koeuth T; Ortmann W; Iwahori A; Elliott MK; Offer S; Skon C; Du L; Novitzke J; Lee AT; Zhao N; Tompkins JD; Altshuler D; Gregersen PK; Cunningham-Rundles C; Harris RS; Her C; Nelson DL; Hammarstrom L; Gilkeson GS; Behrens TW
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2007;31(10):1034-1049
Physical mapping of the giant panda immunoglobulin heavy chain constant region genes
Zhao Z; Zhao Y; Pan-Hammarstroem Q; Liu W; Liu Z; Zhao Y; Li N; Hammarstroem L
Article: JOURNAL OF INFECTIOUS DISEASES. 2006;194(11):1580-1588
Lactobacilli expressing variable domain of llama heavy-chain antibody fragments (lactobodies) confer protection against rotavirus-induced diarrhea
Pant N; Hultberg A; Zhao Y; Svensson L; Pan-Hammarstrom Q; Johansen K; Pouwels PH; Ruggeri FM; Hermans P; Frenken L; Boren T; Marcotte H; Hammarstrom L
Article: INFECTION AND IMMUNITY. 2006;74(11):6293-6299
Host-derived pentapeptide affecting adhesion, proliferation, and local pH in biofilm communities composed of Streptococcus and Actinomyces species
Drobni M; Li T; Kruger C; Loimaranta V; Kilian M; Hammarstrom L; Jornvall H; Bergman T; Stromberg N
Article: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2006;72(4):732-737
Therapeutic effect of llama derived VHH fragments against Streptococcus mutans on the development of dental caries
Kruger C; Hultberg A; Marcotte H; Hermans P; Bezemer S; Frenken LGJ; Hammarstrom L
Article: JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. 2006;26(9):628-636
Cytokine gene expression profiles in human lymphocytes induced by a formula of traditional Chinese medicine, Vigconic VI-28
Pan-Hammarstrom Q; Wen S; Hammarstrom L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(32):12087-12092
Identification of IgF, a hinge-region-containing Ig class, and IgD in Xenopus tropicalis
Zhao Y; Pan-Hammarstrom Q; Yu S; Wertz N; Zhang X; Li N; Butler JE; Hammarstrom L
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2006;14(7):867-875
Linkage of autosomal-dominant common variable immunodeficiency to chromosome 4q
Finck A; Van der Meer JWM; Schaffer AA; Pfannstiel J; Fieschi C; Plebani A; Webster ADB; Hammarstrom L; Grimbacher B
Article: VACCINE. 2006;24(19):4130-4137
Reduction in morbidity of rotavirus induced diarrhoea in mice by yeast produced monovalent llama-derived antibody fragments.
van der Vaart JM; Pant N; Wolvers D; Bezemer S; Hermans PW; Bellamy K; Sarker SA; van der Logt CPE; Svensson L; Verrips CT; Hammarstrom L; van Klinken BJW
Article: INTERNATIONAL IMMUNOLOGY. 2006;18(4):525-536
FcRn mediates elongated serum half-life of human IgG in cattle
Kacskovics I; Kis Z; Mayer B; West AP; Tiangco NE; Tilahun M; Cervenak L; Bjorkman PJ; Goldsby RA; Szenci O; Hammarström L
Article: JOURNAL OF APPLIED MICROBIOLOGY. 2006;100(2):256-263
Expression of single-chain antibody against RgpA protease of Porphyromonas gingivalis in Lactobacillus
Marcotte H; Koll-Klais P; Hultberg A; Zhao Y; Gmür R; Mändar R; Mikelsaar M; Hammarström L
Article: HUMAN GENETICS. 2006;118(6):725-729
Analysis of families with common variable immunodeficiency (CVID) and IgA deficiency suggests linkage of CVID to chromosome 16q
Schaffer AA; Pfannstiel J; Webster ADB; Plebani A; Hammarström L; Grimbacher B
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2006;203(1):99-110
Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation
Pan-Hammarström Q; Lähdesmäki A; Zhao YF; Du LK; Zhao ZH; Wen SC; Ruiz-Perez VL; Dunn-Walters DK; Goodship JA; Hammartström L
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2006;30(12):1203-1215
Cloning and characterization of the dromedary (Camelus dromedarius) neonatal Fc receptor (drFcRn)
Kacskovics I; Mayer B; Kis Z; Frenyo LV; Zhao Y; Muyldermans S; Hammarstrom L
Article: GLYCOBIOLOGY. 2006;16(1):1-10
Carbohydrate-dependent inhibition of Helicobacter pylori colonization using porcine milk
Gustafsson A; Hultberg A; Sjöström R; Kacskovics I; Breimer ME; Borén T; Hammarström L; Holgersson J
Article: MOLECULAR ORAL MICROBIOLOGY. 2005;20(6):354-361
Oral lactobacilli in chronic periodontitis and periodontal health:: species composition and antimicrobial activity
Koll-Klais P; Mändar R; Leibur E; Marcotte H; Hammarström L; Mikelsaar M
Article: MOLECULAR & CELLULAR PROTEOMICS. 2005;4(12):1942-1947
Serum microarrays for large scale screening of protein levels
Janzi M; Ödling J; Pan-Hammarström Q; Sundberg M; Lundeberg J; Uhlén M; Hammarström L; Nilsson P
Article: MOLECULAR BIOTECHNOLOGY. 2005;31(3):221-231
Passive immunization by lactobacilli expressing single-chain antibodies against Streptococcus mutans
Krüger C; Hultberg A; van Dollenweerd C; Marcotte H; Hammarström L
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2005;202(6):733-738
AID from bony fish catalyzes class switch recombination
Barreto VM; Pan-Hammarstrom Q; Zhao YF; Hammarstrom L; Misulovin Z; Nussenzweig MC
Article: NATURE GENETICS. 2005;37(8):820-828
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
Salzer U; Chapel HM; Webster ADB; Pan-Hammarström Q; Schmitt-Graeff A; Schlesier M; Peter HH; Rockstroh JK; Schneider P; Schäffer AA; Hammarström L; Grimbacher B
Article: PEDIATRICS. 2005;116(2):e221-e228
Lactobacillus paracasei strain ST11 has no effect on rotavirus but ameliorates the outcome of nonrotavirus diarrhea in children from Bangladesh
Sarker SA; Sultana S; Fuchs GJ; Alam NH; Azim T; Brüssow H; Hammarström L
Article: BRITISH JOURNAL OF CANCER. 2005;93(2):260-265
Breast and other cancers in 1445 blood relatives of 75 Nordic patients with ataxia telangiectasia
Olsen JH; Hahnemann JMD; Borresen-Dale AL; Tretli S; Kleinerman R; Sankila R; Hammarström L; Robsahm T; Kääriäinen H; Bregård A; Brondum-Nielsen K; Yuen J; Tucker M
Article: GLYCOCONJUGATE JOURNAL. 2005;22(3):109-118
Carbohydrate phenotyping of human and animal milk glycoproteins
Gustafsson A; Kacskovics I; Breimer ME; Hammarström L; Holgersson J
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2005;201(2):189-194
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
Pan-Hammarström Q; Jones AM; Lähdesmäki A; Zhou W; Gatti RA; Hammarström L; Gennery AR; Ehrenstein MR
Article: INTERNATIONAL IMMUNOLOGY. 2005;17(1):95-101
Selective IgG2 deficiency due to a point mutation causing abnormal splicing of the Cγ2 gene
Zhao YF; Pan-Hammarström Q; Zhao ZH; Wen SC; Hammarström L
Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2005;29(1):61-71
Identification of the activation-induced cytidine deaminase gene from zebrafish:: an evolutionary analysis
Zhao YF; Pan-Hammarström Q; Zhao ZH; Hammarström L
Article: CLINICAL IMMUNOLOGY. 2004;113(3):234-240
ICOS deficiency in patients with common variable immunodeficiency
Salzer U; Maul-Pavicic A; Cunningham-Rundles C; Urschel S; Belohradsky BH; Litzman J; Holm A; Franco JL; Plebani A; Hammarstrom L; Skrabl A; Schwinger W; Grimbacher B
Article: CARCINOGENESIS. 2004;25(11):2067-2073
Identification of a functional variant of estrogen receptor beta in an African population
Zhao CY; Xu L; Otsuki M; Toresson G; Koehler K; Pan-Hammarström Q; Hammarström L; Nilsson S; Gustafsson J; Dahlman-Wright K
Article: WORLD JOURNAL OF GASTROENTEROLOGY. 2004;10(14):2063-2066
Effects of fucosylated milk of goat and mouse on Helicobacter pylori binding to Lewis b antigen
Xu H-T; Zhao Y-F; Lian Z-X; Fan B-L; Zhao Z-H; Yu S-Y; Dai Y-P; Wang L-L; Niu H-L; Li N; Hammarstrom L; Boren T; Sjostrom R
Article: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 2004;98(1-2):85-89
The neonatal Fc receptor (FcRn) is expressed in the bovine lung
Mayer B; Kis Z; Kaján G; Frenyó LV; Hammarström L; Kacskovics I
Article: CARIES RESEARCH. 2004;38(1):9-14
The effects of egg-derived antibodies to glucosyltransferases on dental caries in rats
Krüger C; Pearson SK; Kodama Y; Smith AV; Bowen WH; Hammarström L
Article: JOURNAL OF APPLIED MICROBIOLOGY. 2004;97(4):749-756
The aggregation-promoting factor of Lactobacillus crispatus M247 and its genetic locus
Marcotte H; Ferrari S; Cesena C; Hammarström L; Morelli L; Pozzi G; Oggioni MR
Article: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 2003;96(3-4):229-233
Presence of the di-leucine motif in the cytoplasmic tail of the pig FcRn α chain
Zhao YF; Kacskovics I; Zhao ZH; Hammarström L
Article: JOURNAL OF NEUROIMMUNOLOGY. 2003;144(1-2):100-104
Lack of correlation between the reduction of serum immunoglobulin concentration and the CTG repeat expansion in patients with type I Dystrofia Myotonica
Pan-Hammarström Q; Wen SC; Ghanaat-Pour H; Solders G; Forsberg H; Hammarström L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;108(3):451-455
Oral administration of antibodies as prophylaxis and therapy in Campylobacter jejuni-infected chickens.
Tsubokura K; Berndtson E; Bogstedt A; Kaijser B; Kim M; Ozeki M; Hammarström L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;105(2):266-273
Reduction in serum levels of antimitochondrial (M2) antibodies following immunoglobulin therapy in severe combined immunodeficient (SCID) mice reconstituted with lymphocytes from patients with primary biliary cirrhosis (PBC)
Abedi MR; Hammarstrom L; Broome U; Angelin B; Smith CIE; Christensson B
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;105(2):202-204
Helicobacter pylori infections in IgA deficiency: Lack of role for the secretory immune system
Bogstedt AK; Nava S; Wadstrom T; Hammarstrom L
Article: BMC BIOTECHNOLOGY. 2003;3:15
In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii -: art. no. 15
Ricci S; Macchia G; Ruggiero P; Maggi T; Bossù P; Xu L; Medaglini D; Tagliabue A; Hammarström L; Pozzi G; Boraschi D
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(37):35024-35032
Physical mapping of the bovine immunoglobulin heavy chain constant region gene locus
Zhao YF; Kacskovics I; Rabbani H; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2003;171(3):1312-1318
The porcine Ig δ gene:: Unique constant region domain in its chimeric splicing of the first heavy chain transcripts^1,2
Zhao YF; Pan-Hammarström Q; Kacskovics I; Hammarström L
Article: ENDOCRINOLOGY. 2003;144(8):3541-3546
Human estrogen receptor β 548 is not a common variant in three distinct populations
Xu L; Pan-Hammarström Q; Försti A; Hemminki K; Hammarström L; Labuda D; Gustafsson J; Dahlman-Wright K
Article: JOURNAL OF IMMUNOLOGY. 2003;170(7):3707-3716
ATM is not required in somatic hypermutation of V_H, but is involved in the introduction of mutations in the switch μ region
Pan-Hammarström Q; Dai SJ; Zhao YF; van Dijk-Härd IF; Gatti RA; Borresen-Dale AL; Hammarström L
Article: IMMUNOLOGY. 2003;108(3):288-295
Cloning of the complete rat immunoglobulin δ gene:: evolutionary implications
Zhao YF; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2003;170(5):2765-2775
Fine-scale mapping at IGAD1 and genome-wide genetic linkage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency
Kralovicova J; Hammarström L; Plebani A; Webster ADB; Vorechovsky I
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2002;37(12):1380-1385
Bovine anti-Helicobacter pylori antibodies for oral immunotherapy
Casswall TH; Nilsson HO; Björck L; Sjöstedt S; Xu L; Nord CE; Borén T; Wadström T; Hammarström L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;130(3):495-500
Cancer risk among patients with IgA deficiency or common variable immunodeficiency and their relatives:: a combined Danish and Swedish study
Mellemkjær L; Hammarström L; Andersen V; Yuen J; Heilmann C; Barington T; Björkander J; Olsen JH
Article: IMMUNOLOGY. 2002;107(3):288-296
Redistribution of the sheep neonatal Fc receptor in the mammary gland around the time of parturition in ewes and its localization in the small intestine of neonatal lambs
Mayer B; Zolnai A; Frenyó LV; Jancsik V; Szentirmay Z; Hammarström L; Kacskovics I
Article: JOURNAL OF IMMUNOLOGY. 2002;169(8):4408-4416
Artiodactyl IgD: The missing link
Zhao YF; Kacskovics I; Pan Q; Liberles DA; Geli J; Davis SK; Rabbani H; Hammarstrom L
Article: JOURNAL OF CLINICAL INVESTIGATION. 2002;110(7):1029-1035
Clinical and molecular analysis of patients with defects in μ heavy chain gene
Granados EL; Porpiglia AS; Hogan MB; Matamoros N; Krasovec S; Pignata C; Smith CIE; Hammarstrom L; Bjorkander J; Belohradsky BH; Casariego GF; Rodriguez MCG; Conley ME
Article: HLA. 2002;60(3):266-267
The HLA-DRA*0102 allele: Correct nucleotide sequence and associated HLA haplotypes
Kralovicova J; Marsh SGE; Waller MJ; Hammarstrom L; Vorechovsky I
Article: SCIENCE. 2002;297(5581):573-578
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation
Mahdavi J; Sondén B; Hurtig M; Olfat FO; Forsberg L; Roche N; Ångström J; Larsson T; Teneberg S; Karlsson KA; Altraia S; Wadström T; Kersulyte D; Berg DE; Dubois A; Petersson C; Magnusson KE; Norberg T; Lindh F; Lundskog BB; Arnqvist A; Hammarström L; Borén T
Article: NATURE BIOTECHNOLOGY. 2002;20(7):702-706
In situ delivery of passive immunity by lactobacilli producing single-chain antibodies
Krüger C; Hu YZ; Pan Q; Marcotte H; Hultberg A; Delwar D; van Dalen PJ; Pouwels PH; Leer RJ; Kelly CG; van Dollenweerd C; Ma JK; Hammarström L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2002;32(5):1300-1308
Alternative end joining during switch recombination in patients with Ataxia-Telangiectasia
Pan Q; Petit-Frére C; Lädesmäki A; Gregorek H; Chrzanowska KH; Hammarström L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;112(2):341-346
Induction of unresponsiveness against IgA in IgA-deficient patients on subcutaneous immunoglobulin infusion therapy
Sundin U; Nava S; Hammarström L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(12):3622-3630
Regulation of switching and production of IgA in human B cells in donors with duplicated α1 genes
Pan Q; Petit-Frére C; Dai SJ; Huang P; Morton HC; Brandtzaeg P; Hammarström L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(12):3469-3474
Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene
Liippo J; Nera KP; Veistinen E; Lähdesmäki A; Postila V; Kimby E; Riikonen P; Hammarström L; Pelkonen J; Lassila O
Article: NATURE GENETICS. 2001;29(1):22-23
Does 77C→G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?
Vorechovsky I; Kralovicova J; Tchilian E; Masterman T; Zhang ZP; Ferry B; Misbah S; Chapel H; Webster D; Hellgren D; Anvret M; Hillert J; Hammarstrom L; Beverley PC
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2001;9(8):590-598
Short tandem repeat (STR) haplotypes in HLA:: an integrated 50-kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region
Vorechovsky I; Kralovicova J; Laycock MD; Webster ADB; Marsh SGE; Madrigal A; Hammarström L
Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2001;93(2):121-127
Cancer in patients with ataxia-telangiectasia and in their relatives in the Nordic countries
Olsen JH; Hahnemann JM; Borresen-Dale AL; Brondum-Nielsen K; Hammarström L; Kleinerman R; Käätriäinen H; Lönnqvist T; Sankila R; Seersholm N; Tretli S; Yuen J; Boice JD; Tucker M
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2001;32(1):19-25
Randomized, placebo-controlled, clinical trial of hyperimmunized chicken egg yolk immunoglobulin in children with rotavirus diarrhea
Sarker SA; Casswall TH; Juneja YR; Hoq E; Hossain I; Fuchs GJ; Hammarström L
Article: CLINICAL INFECTIOUS DISEASES. 2000;31(5):1175-1182
Relative neutralizing activity in polyspecific IgM, IgA, and IgG preparations against group A streptococcal superantigens
Norrby-Teglund A; Ihendyane N; Kansal R; Basma H; Kotb M; Andersson J; Hammarström L
Article: IMMUNOLOGY. 2000;101(3):348-353
Mapping of the chicken immunoglobulin heavy-chain constant region gene locus reveals an inverted α gene upstream of a condensed υ gene
Zhao Y; Rabbani H; Shimizu A; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2000;165(8):4725-4730
Impaired antibody affinity maturation process characterizes a subset of patients with common variable immunodeficiency
Bonhomme D; Hammarström L; Webster D; Chapel H; Hermine O; Le Deist F; Lepage E; Romeo PH; Levy Y
Article: LAKARTIDNINGEN. 2000;97(40):4461-4467
[Ataxia-telangiectasia surveyed in Sweden].
Lähdesmäki A; Arinbjarnarson K; Arvidsson J; el Segaier M; Fasth A; Fernell E; Gustafsson D; Oxelius VA; Risberg K; Yuen J; Zetterlund P; von Zweigbergk M; Ahsgren I; Hammarström L
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2000;111(1):230-238
Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia
Rezvany MR; Jeddi-Tehrani M; Rabbani H; Rudén U; Hammarström L; Österborg A; Wigzell H; Mellstedt H
Article: HUMAN MUTATION. 2000;16(3):232-246
Characterization of ATM mutations in 41 Nordic families with ataxia telangiectasia
Laake K; Jansen L; Hahnemann JM; Brondum-Nielsen K; Lönnqvist T; Kääriäinen H; Sankila R; Lähdesmäki A; Hammarström L; Yuen J; Tretli S; Heiberg A; Olsen JH; Tucker M; Kleinerman R; Borresen-Dale AL
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(8):2388-2393
An allotype-associated polymorphism in the γ3 promoter determines the germ-line γ3 transcriptional rate but does not influence switching and subsequent IgG3 production
Pan Q; Petit-Frére C; Hammarström L
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2000;35(7):711-718
Treatment of enterotoxigenic and enteropathogenic Escherichia coli-induced diarrhoea in children with bovine immunoglobulin milk concentrate from hyperimmunized cows:: A double-blind, placebo-controlled, clinical trial
Casswall TH; Sarker SA; Faruque SM; Weintraub A; Albert MJ; Fuchs GJ; Alam NH; Dahlström AK; Link H; Brüssow H; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2000;164(12):6380-6386
Regulation of germline promoters by the two human Ig heavy chain 3′ α enhancers
Hu YZ; Pan Q; Pardali E; Mills FC; Bernstein RM; Max EE; Sideras P; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2000;164(8):4408-4416
Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency:: Identification and characterization of haplotypes shared by affected members of 101 multiple-case families
Vorechovsky I; Cullen M; Carrington M; Hammarström L; Webster ADB
Article: CLINICAL OTOLARYNGOLOGY. 2000;25(2):161-168
Children with recurrent episodes of acute otitis media:: the effect of local administration of immunoglobulin G on acute otitis media, colonization and turnover of non-encapsulated Haemophilus influenzae in the nasopharynx
Lindberg K; Hammarström L; Samuelson A; Rynnel-Dagöö B
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(4):1019-1029
Regulation of the promoter for human immunoglobulin γ3 germ-line transcription and its interaction with the 3′α enhancer
Pan Q; Petit-Frére C; Stavnezer J; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 2000;164(4):1889-1897
Cloning and characterization of the bovine MHC class I-like Fc receptor
Kacskovics I; Wu Z; Simister NE; Frenyó LV; Hammarström L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1999;29(9):2779-2787
Targeting of human switch recombination breakpoints:: implications for the mechanism of μ-γ isotype switching
Pan Q; Hammarström L
Article: JOURNAL OF IMMUNOLOGY. 1999;163(4):2236-2242
A putative susceptibility locus on chromosome 18 is not a major contributor to human selective IgA deficiency:: Evidence from meiotic mapping of 83 multiple-case families
Vorechovsky I; Blennow E; Nordenskjöld M; Webster ADB; Hammarström L
Article: LAKARTIDNINGEN. 1999;96(18):2191-2192
[Gamma-globulin shortage threatens a patient group].
Palmblad J; Hammarström L
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1999;64(4):1096-1109
Genetic linkage of IgA deficiency to the major histocompatibility complex:: Evidence for allele segregation distortion, parent-of-origin penetrance differences, and the role of anti-IgA antibodies in disease predisposition
Vorechovsky I; Webster ADB; Plebani A; Hammarström L
Article: BONE MARROW TRANSPLANTATION. 1999;23(3):283-290
Fungal prophylaxis by reduction of fungal colonization by oral administration of bovine anti-Candida antibodies in bone marrow transplant recipients
Tollemar J; Gross N; Dolgiras N; Jarstrand C; Ringdén O; Hammarström L
Article: SWEDISH DENTAL JOURNAL. SUPPLEMENT. 1999;23(1):11-15
Activation of human B-lymphocytes by Prevotella intermedia
Homayounfar A; Bergström J; Hammarström L
Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 1998;17(12):1149-1154
Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum.
Sarker SA; Casswall TH; Mahalanabis D; Alam NH; Albert MJ; Brüssow H; Fuchs GJ; Hammerström L
Article: JOURNAL OF IMMUNOLOGY. 1998;161(7):3520-3526
Characterization of human γ4 switch region polymorphisms suggests a meiotic recombinational hot spot within the Ig locus:: Influence of S region length on IgG4 production
Pan Q; Rabbani H; Hammarström L
Article: CANCER RESEARCH. 1998;58(11):2293-2297
Ataxia-telangiectasia and T-cell leukemias:: No evidence for somatic ATM mutation in sporadic T-ALL or for hypermethylation of the ATM-NPAT/E14 bidirectional promoter in T-PLL
Luo LP; Lu FM; Hart S; Foroni L; Rabbani H; Hammarström L; Webster ADB; Vorechovsky I
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 1998;12(6):563-568
Treatment of Helicobacter pylori infection in infants in rural Bangladesh with oral immunoglobulins from hyperimmune bovine colostrum
Casswall TH; Sarker SA; Albert MJ; Fuchs GJ; Bergstrom M; Bjorck L; Hammarstrom L
Article: IMMUNOLOGY. 1998;93(4):581-588
Characterization of the gene for the membrane and secretory form of the IgM heavy-chain constant region gene (Cμ) of the cow (Bos taurus)
Mousavi M; Rabbani H; Pilström L; Hammarström L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(11):2920-2926
Structural analysis of human gamma 3 intervening regions and switch regions: implication for the low frequency of switching in IgG3-deficient patients
Pan Q; Lindersson Y; Sideras P; Hammarstrom L
Article: IMMUNOLOGY. 1997;92(3):369-373
Characterization of the bovine epsilon gene
Mousavi M; Rabbani H; Hammarstrom L
Article: THE LANCET. 1997;350(9081):865
Prophylactic therapy for selective IgA deficiency
Gustafson R; Gardulf A; Granert C; Hansen S; Hammarstrom L
Article: IMMUNOGENETICS. 1997;46(4):326-331
Polymorphism of the IGHG3 gene in cattle
Rabbani H; Brown WR; Butler JE; Hammarstrom L
Article: JOURNAL OF PEDIATRICS. 1997;131(1):47-54
Clinical spectrum of X-linked hyper-IgM syndrome
Levy J; EspanolBoren T; Thomas C; Fischer A; Tovo P; Bordigoni P; Resnick I; Fasth A; Baer M; Gomez L; Sanders EAM; Tabone MD; Plantaz D; Etzioni A; Monafo V; Abinun M; Hammarstrom L; Abrahamsen T; Jones A; Finn A; Klemola T; DeVries E; Sanal O; Peitsch MC; Notarangelo LD
Article: JOURNAL OF IMMUNOLOGY. 1997;158(12):5849-5859
Allotype-associated variation in the human gamma 3 switch region as a basis for differences in IgG3 production
Pan Q; Rabbani H; Mills FC; Severinson E; Hammarstrom L
Article: INTERNATIONAL JOURNAL OF CANCER. 1997;71(4):624-629
Preventive effect of IgG from EBV-seropositive donors on the development of human lympho-proliferative disease in SCID mice
Abedi MR; Linde A; Christensson B; Mackett M; Hammarstrom L; Smith CE
Article: IMMUNOLOGY. 1997;91(1):1-6
Characterization of the bovine C alpha gene
Brown WR; Rabbani H; Butler JE; Hammarstrom L
Article: TRANSFUSION. 1997;37(3):313-320
At least three hepatitis C virus strains implicated in Swedish and Danish patients with intravenous immunoglobulin-associated hepatitis C.
Widell A; Zhang YY; Andersson-Gäre B; Hammarström L
Article: HUMAN MUTATION. 1997;9(5):418-425
Mutation pattern in Bruton's tyrosine kinase gene in 26 unrelated patients with X-linked agammaglobulinemia
Vorechovsky I; Luo LP; Hertz JM; Froland SS; Klemola T; Fiorini M; Quinti I; Paganelli R; Ozsahin H; Hammarstrom L; Webster ADB; Smith CIE
Article: IMMUNOGENETICS. 1996;45(2):136-141
Duplications and deletions of the human IGHC locus: Evolutionary implications
Rabbani H; Pan Q; Kondo N; Smith CIE; Hammarstrom L
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 1996;85(12):1511-1513
Fatal outcome of disseminated Mycobacterium avium infection in childhood. A case of primary incompetent monocyte/macrophage function?
Heurlin N; Dahlqvist G; Elinder G; Hammarstrom L; Petrini B
Article: CANCER RESEARCH. 1996;56(18):4130-4133
ATM mutations in cancer families
Vorechovsky I; Luo LP; Lindblom A; Negrini M; Webster ADB; Croce CM; Hammarstrom L
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 1996;85(9):1126-1128
Oral IgA-IgG treatment of chronic non-specific diarrhoea in infants and children
Casswall TH; Hammarstrom L; Veress B; Nord CE; Bogstedt A; Brockstedt U; Dahlstrom KA
Article: BIODRUGS. 1996;6(2):108-116
Subcutaneous administration of immunoglobulins - What are the advantages?
Gardulf A; Hammarstrom L
Article: APMIS. 1996;104(7-8):563-574
Semiquantitative estimation of Shigella antigen-specific antibodies: Correlation with disease severity during shigellosis
Islam D; Wretlind B; Hammarstrom L; Christensson B; Lindberg AA
Article: CANCER RESEARCH. 1996;56(12):2726-2732
The ATM gene and susceptibility to breast cancer: Analysis of 38 breast tumors reveals no evidence for mutation
Vorechovsky I; Rasio D; Luo LP; Monaco C; Hammarstrom L; Webster ADB; Zaloudik J; BarbantiBrodano G; James M; Russo G; Croce CM; Negrini M
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 1996;85(2):125-128
Passive immunity against diarrhoea.
Bogstedt AK; Johansen K; Hatta H; Kim M; Casswall T; Svensson L; Hammarström L
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 1996;4(6):352-355
Exon-scanning mutation analysis of the ATM gene in patients with ataxia-telangiectasia
Vorechovsky I; Luo LP; Prudente S; Chessa L; Russo G; Kanariou M; James M; Negrini M; Webster ADB; Hammarstrom L
Article: HUMAN MOLECULAR GENETICS. 1995;4(12):2403-2405
IMPROVED OLIGONUCLEOTIDE PRIMER SET FOR MOLECULAR DIAGNOSIS OF X-LINKED AGAMMAGLOBULINEMIA - PREDOMINANCE OF AMINO-ACID SUBSTITUTIONS IN THE CATALYTIC DOMAIN OF BRUTONS TYROSINE KINASE
VORECHOVSKY I; LUO LP; DESAINTBASILE G; HAMMARSTROM L; WEBSTER ADB; SMITH CIE
Article: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1995;77(2):185-192
FAMILY AND LINKAGE STUDY OF SELECTIVE IGA DEFICIENCY AND COMMON VARIABLE IMMUNODEFICIENCY
VORECHOVSKY I; ZETTERQUIST H; PAGANELLI R; KOSKINEN S; WEBSTER ADB; BJORKANDER J; SMITH CIE; HAMMARSTROM L
Article: JOURNAL OF ADVANCED NURSING. 1995;21(5):917-927
LIFELONG TREATMENT WITH GAMMA-GLOBULIN FOR PRIMARY ANTIBODY DEFICIENCIES - THE PATIENTS EXPERIENCES OF SUBCUTANEOUS SELF-INFUSIONS AND HOME THERAPY
GARDULF A; BJORVELL H; ANDERSEN V; BJORKANDER J; ERICSON D; FROLAND SS; GUSTAFSON R; HAMMARSTROM L; NYSTROM T; SOEBERG B; SMITH CIE
Article: HUMAN MOLECULAR GENETICS. 1995;4(4):693-700
IDENTIFICATION OF BTK MUTATIONS IN 20 UNRELATED PATIENTS WITH X-LINKED AGAMMAGLOBULINEMIA (XLA)
JIN H; WEBSTER ADB; VIHINEN M; SIDERAS P; VORECHOVSKY I; HAMMARSTROM L; BERNATOWSKAMATUSZKIEWICZ E; SMITH CIE; BOBROW M; VETRIE D
Article: THE LANCET. 1995;345(8946):365-369
SUBCUTANEOUS IMMUNOGLOBULIN REPLACEMENT IN PATIENTS WITH PRIMARY ANTIBODY DEFICIENCIES - SAFETY AND COSTS
GARDULF A; ANDERSEN V; BJORKANDER J; ERICSON D; FROLAND SS; GUSTAFSON R; HAMMARSTROM L; JACOBSEN MB; JONSSON E; MOLLER G; NYSTROM T; SOEBERG B; SMITH CIE
Article: HUMAN MOLECULAR GENETICS. 1995;4(1):51-58
DNA-BASED MUTATION ANALYSIS OF BRUTONS TYROSINE KINASE GENE IN PATIENTS WITH X-LINKED AGAMMAGLOBULINEMIA
VORECHOVSKY I; VIHINEN M; DESAINTBASILE G; HONSOVA S; HAMMARSTROM L; MULLER S; NILSSON L; FISCHER A; SMITH CIE
Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1995;371A:685-690
Biological properties of yolk immunoglobulins.
Janson AK; Smith CI; Hammarström L
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Corrigendum: GENOME MEDICINE. 2024;16(1):6
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (vol 15, 22, 2023)
Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Tayoun AA; Aiuti A; Darazam IA; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; Zein LE; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Akcan OM; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
Editorial comment: THE LANCET INFECTIOUS DISEASES. 2024;24(1):e7-e9
Neutralisation activity of mucosal IgA against XBB sublineages and BA.2.86
Zuo F; Cao Y; Sun R; Yisimayi A; Du L; Bertoglio F; Schubert M; Guerra C; Cavalli A; Hust M; Robbiani DF; Abolhassani H; Xie XS; Hammarstroem L; Marcotte H; Pan-Hammarstroem Q
Preprint: BIORXIV. 2023;BIORXIV
Vaccination with Helicobacter pylori attachment proteins protects against gastric cancer.
Bugaytsova JA; Piddubnyi A; Tkachenko I; Rakhimova L; Edlund JO; Thorell K; Marcotte H; Lundquist A; Schön K; Lycke N; Suerbaum S; Schulz C; Malfertheiner P; Hansen LM; Solnick JV; Moskalenko R; Hammarström L; Borén T
Preprint: BIORXIV. 2023;BIORXIV
Helicobacter pylori attachment-blocking antibodies protect against duodenal ulcer disease.
Bugaytsova JA; Moonens K; Piddubnyi A; Schmidt A; Edlund JO; Lisiutin G; Brännström K; Chernov YA; Thorel K; Tkachenko I; Sharova O; Vikhrova I; Butsyk A; Shubin P; Chyzhma R; Johansson DX; Marcotte H; Sjöström R; Shevtsova A; Bylund G; Rakhimova L; Lundquist A; Berhilevych O; Kasianchuk V; Loboda A; Ivanytsia V; Hultenby K; Persson MAA; Gomes J; Matos R; Gartner F; Reis CA; Whitmire JM; Merrell DS; Pan-Hammarström Q; Landström M; Oscarson S; D'Elios MM; Agreus L; Ronkainen J; Aro P; Engstrand L; Graham DY; Kachkovska V; Mukhopadhyay A; Chaudhuri S; Karmakar BC; Paul S; Kravets O; Camorlinga M; Torres J; Berg DE; Moskalenko R; Haas R; Remaut H; Hammarström L; Borén T
Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(4):671-674
Foreword to the English Translation of Kostmann's Memoirs
Casanova J-L; Hammarstrom L
Letter: THE LANCET REGIONAL HEALTH. WESTERN PACIFIC. 2023;33:100762
Heterologous inactivated virus/mRNA vaccination response to BF.7, BQ.1.1, and XBB.1
Zuo F; Sun R; Abolhassani H; Du L; Wang Y; Vlachiotis S; Bertoglio F; Schubert M; Rezaei N; Chavoshzadeh Z; Guerra C; Cavalli A; Andrell J; Kumagai-Braesch M; Xue Y; Cao Y; Hust M; Robbiani DF; Xie XS; Hammarstrom L; Marcotte H; Pan-Hammarstrom Q
Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):655
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits (vol 13, 6859, 2022)
Liu L; Khan A; Sanchez-Rodriguez E; Zanoni F; Li Y; Steers N; Balderes O; Zhang J; Krithivasan P; LeDesma RA; Fischman C; Hebbring SJ; Harley JB; Moncrieffe H; Kottyan LC; Namjou-Khales B; Walunas TL; Knevel R; Raychaudhuri S; Karlson EW; Denny JC; Stanaway IB; Crosslin D; Rauen T; Floege J; Eitner F; Moldoveanu Z; Reily C; Knoppova B; Hall S; Sheff JT; Julian BA; Wyatt RJ; Suzuki H; Xie J; Chen N; Zhou X; Zhang H; Hammarstroem L; Viktorin A; Magnusson PKE; Shang N; Hripcsak G; Weng C; Rundek T; Elkind MSV; Oelsner EC; Barr RG; Ionita-Laza I; Novak J; Gharavi AG; Kiryluk K
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2022;387(21):e55
Mucosal IgA against SARS-CoV-2 Omicron Infection
Zuo F; Marcotte H; Hammarstrom L; Pan-Hammarstrom Q
Editorial comment: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2022;7(1):294
Limited cross-variant neutralization after primary Omicron infection: consideration for a variant-containing booster
Marcotte H; Hammarstrom L; Pan-Hammarstrom Q
Review: ACTA BIOCHIMICA ET BIOPHYSICA SINICA. 2022;54(6):836-846
SARS-CoV-2 infection in patients with inborn errors of immunity due to DNA repair defects
Wang Y; Abolhassani H; Hammarstrom L; Pan-Hammarstrom Q
Preprint: RES SQ. 2022;RES SQ
The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.
Manry J; Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martínez A; Yang R; Haljasmägi L; Migaud M; Särekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garçon P; Rivière JG; Lagier J-C; Gentile S; Rosen L; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Mégarbane B; Triantafyllia V; Fekkar A; Heath J; Franco J; Anaya J-M; Solé-Violán J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte O; Zhang Y; Snow A; Holland S; Biggs C; Moncada-Vélez M; Arias A; Lorenzo L; Boucherit S; Anglicheau D; Planas A; Haerynck F; Duvlis S; Nussbaum R; Ozcelik T; Keles S; Bousfiha A; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz C; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros L; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye S; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann N; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes L; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig M; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer A; Kennelly S; Bourke N; Halwani R; Sharif-Askari F; Dorgham K; Sallette J; Mehlal-Sedkaoui S; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh D; Erikstrup C; Condino-Neto A; Prando C; Bondarenko A; Spaan A; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton R; Mane S; Anderson M; Boisson B; Béziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; deLamballerie X; Burdet C; Bouadma L; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen P; Rodríguez-Gallego C; Piemonti L; Notarangelo L; Su H; Kisand K; Okada S; Puel A; Jouanguy E; Rice C; Tiberghien P; Zhang Q; Casanova J-L; Abel L; Cobat A
Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2021;21(6):553-558
Antibody therapy for COVID-19
Hammarstrom L; Marcotte H; Piralla A; Baldanti F; Pan-Hammarstrom Q
Review: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2021;32(8):1601-1615
Known and potential molecules associated with altered B cell development leading to predominantly antibody deficiencies
Amirifar P; Yazdani R; Azizi G; Ranjouri MR; Durandy A; Plebani A; Lougaris V; Hammarstrom L; Aghamohammadi A; Abolhassani H
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:720025
Hallmarks of Cancers: Primary Antibody Deficiency Versus Other Inborn Errors of Immunity
Abolhassani H; Wang Y; Hammarstroem L; Pan-Hammarstroem Q
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2020;16(7):717-732
Global systematic review of primary immunodeficiency registries
Abolhassani H; Azizi G; Sharifi L; Yazdani R; Mohsenzadegan M; Delavari S; Sohani M; Shirmast P; Chavoshzadeh Z; Mahdaviani SA; Kalantari A; Tavakol M; Jabbari-Azad F; Ahanchian H; Momen T; Sherkat R; Sadeghi-Shabestari M; Aleyasin S; Esmaeilzadeh H; Al-Herz W; Bousfiha AA; Condino-Neto A; Seppanen M; Sullivan KE; Hammarstrom L; Modell V; Modell F; Quinn J; Orange JS; Aghamohammadi A
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;146(1):58-60
Development of passive immunity against SARS-CoV-2 for management of immunodeficient patients-a perspective
Hammarstrom L; Abolhassani H; Baldanti F; Marcotte H; Pan-Hammarstrom Q
Review: BLOOD. 2020;135(9):656-667
Current genetic landscape in common variable immune deficiency
Abolhassani H; Hammarstrom L; Cunningham-Rundles C
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2020;11:633266
Editorial: Screening for Primary Immunodeficiency Disorders (PIDDs) in Neonates
Hossny E; Condino-Neto A; Hammarstrom L; Walter JE
Letter: JOURNAL OF CLINICAL IMMUNOLOGY. 2019;39(2):131-134
Compound Heterozygous Mutations of IL2-Inducible T cell Kinase in a Swedish Patient: the Importance of Early Genetic Diagnosis
Fang M; Abolhassani H; Pan-Hammarstroem Q; Sandholm E; Liu X; Hammarstrom L
Review: ALLERGY, ASTHMA & CLINICAL IMMUNOLOGY. 2019;15:2
IL2RG hypomorphic mutation: identification of a novel pathogenic mutation in exon 8 and a review of the literature
Lim CK; Abolhassani H; Appelberg SK; Sundin M; Hammarstrom L
Letter: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2018;29(4):453-456
Kappa-deleting recombination excision circle levels remain low or undetectable throughout life in patients with X-linked agammaglobulinemia
King J; Borte S; Brodszki N; von Dobeln U; Smith CIE; Hammarstrom L
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;141(4):1217-1219
Defects in plasma cell differentiation are associated with primary immunodeficiency in human subjects
Pan-Hammarstrom Q; Abolhassani H; Hammarstrom L
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(5):1713-1716.e6
Costs associated with treatment of severe combined immunodeficiency-rationale for newborn screening in Sweden
Gardulf A; Winiarski J; Thorin M; Arnlind MH; von Dobeln U; Hammarstrom L
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2016;12(12):1321-1335
Monogenic mutations associated with IgA deficiency
Abolhassani H; Aghamohammadi A; Hammarstrom L
Published conference paper: JOURNAL OF CLINICAL IMMUNOLOGY. 2016;36:68-75
Next Generation Sequencing Data Analysis in Primary Immunodeficiency Disorders - Future Directions
Fang M; Abolhassani H; Lim CK; Zhang J; Hammarstrom L
Review: INTERNATIONAL REVIEWS OF IMMUNOLOGY. 2016;35(1):7-24
Evaluation of Known Defective Signaling-Associated Molecules in Patients Who Primarily Diagnosed as Common Variable Immunodeficiency
Yazdani R; Abolhassani H; Rezaei N; Azizi G; Hammarstroem L; Aghamohammadi A
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2016;4(1):38-59
International Consensus Document (ICON): Common Variable Immunodeficiency Disorders
Bonilla FA; Barlan I; Chapel H; Costa-Carvalho BT; Cunningham-Rundles C; de la Morena MT; Espinosa-Rosales FJ; Hammarstrom L; Nonoyama S; Quinti I; Routes JM; Tang MLK; Warnatz K
Review: JOURNAL OF CLINICAL IMMUNOLOGY. 2016;36(1):33-45
Spectrum of Phenotypes Associated with Mutations in LRBA
Alkhairy OK; Abolhassani H; Rezaei N; Fang M; Andersen KK; Chavoshzadeh Z; Mohammadzadeh I; El-Rajab MA; Massaad M; Chou J; Aghamohammadi A; Geha RS; Hammarstrom L
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2015;11(11):1229-1243
Different brands of intravenous immunoglobulin for primary immunodeficiencies: how to choose the best option for the patient?
Abolhassani H; Asgardoon MH; Rezaei N; Hammarstrom L; Aghamohammadi A
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2015;11(2):289-302
Important differences in the diagnostic spectrum of primary immunodeficiency in adults versus children
Abolhassani H; Rezaei N; Mohammadinejad P; Mirminachi B; Hammarstrom L; Aghamohammadi A
Editorial comment: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2015;25(3):218-220
Common Variable Immunodeficiency or Late-Onset Combined Immunodeficiency: A New Hypomorphic JAK3 Patient and Review of the Literature
Abolhassani H; Cheraghi T; Rezaei N; Aghamohammadi A; Hammarstrom L
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(1):226-228
Combined newborn screening for familial hemophagocytic lymphohistiocytosis and severe T- and B-cell immunodeficiencies
Borte S; Meeths M; Liebscher I; Krist K; Nordenskjold M; Hammarstrom L; von Dobeln U; Henter J-I; Bryceson YT
Review: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(4):393-397
The Case for Mandatory Newborn Screening for Severe Combined Immunodeficiency (SCID)
Gaspar HB; Hammarstrom L; Mahlaoui N; Borte M; Borte S
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;133(4):1222-1225
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency
Pieper K; Rizzi M; Speletas M; Smulski CR; Sic H; Kraus H; Salzer U; Fiala GJ; Schamel WW; Lougaris V; Plebani A; Hammarstrom L; Recher M; Germenis AE; Grimbacher B; Warnatz K; Rolink AG; Schneider P; Notarangelo LD; Eibel H
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;133(4):1208-1211
Impact of Down syndrome on the performance of neonatal screening assays for severe primary immunodeficiency diseases
Verstegen RHJ; Borte S; Bok LA; van Zwieten PHT; von Dobeln U; Hammarstrom L; de Vries E
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2014;10(3):385-396
Molecular diagnosis of primary immunodeficiency diseases in a developing country: Iran as an example
Latif AH; Tabassomi F; Abolhassani H; Hammarstrom L
Review: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2014;24(1):6-22
Genetic Defects in B-Cell Development and Their Clinical Consequences
Abolhassani H; Parvaneh N; Rezaei N; Hammarstrom L; Aghamohammadi A
Review: CURRENT OPINION IN IMMUNOLOGY. 2013;25(5):629-638
New facets of antibody deficiencies
Liadaki K; Sun J; Hammarstrom L; Pan-Hammarstrom Q
Corrigendum: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;173(1):161
Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients (vol 172, pg 63, 2013)
Wong GK; Goldacker S; Winterhalter C; Grimbacher B; Chapel H; Lucas M; Alecsandru D; McEwen D; Quinti I; Martini H; Milito C; Schmidt RE; Ernst D; Espanol T; Vidaller A; Carbone J; Fernandez-Cruz E; Lougaris V; Plebani A; Kutukculer N; Gonzalez-Granado LI; Contreras R; Kiani-Alikhan S; Ibrahim MAA; Litzman J; Jones A; Gaspar HB; Hammarstrom L; Baumann U; Warnatz K; Huissoon AP
Editorial comment: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2013;23(1):50-51
A Novel CD40 Ligand Mutation in a Patient With Pneumonia, Neutropenia, and Hyperimmunoglobulin M Phenotype
Mohammadzadeh I; Shahbaznejad L; Wang N; Farhadi E; Aghamohammadi A; Hammarstrom L; Rezaei N
Review: CURRENT OPINION IN HEMATOLOGY. 2013;20(1):48-54
Guidelines for newborn screening of primary immunodeficiency diseases
Borte S; von Dobelin U; Hammarstrom L
Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2012;12(6):602-608
IgA deficiency: what is new?
Wang N; Hammarstrom L
Other: JOURNAL OF IMMUNOLOGY. 2012;188(7):2948-2955
The gene involved in X-linked agammaglobulinaemia is member of the src family of protein-tyrosine kinases (Reprinted from Nature, vol 391, pg 226, 1993)
Vetrie D; Vorechovsky I; Sideras P; Holland J; Davies A; Flinter F; Hammarstrom L; Kinnon C; Levinsky R; Bobrow M; Smith CIE; Bentley DR
Review: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2011;35(9):975-981
The immunoglobulin δ gene in jawed vertebrates: A comparative overview
Sun Y; Wei Z; Hammarstrom L; Zhao Y
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;128(1):223-U352
Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects
Nakagawa N; Imai K; Kanegane H; Sato H; Yamada M; Kondoh K; Okada S; Kobayashi M; Agematsu K; Takada H; Mitsuiki N; Oshima K; Ohara O; Suri D; Rawat A; Singh S; Pan-Hammarstroem Q; Hammarstroem L; Reichenbach J; Seger R; Ariga T; Hara T; Miyawaki T; Nonoyama S
Published conference paper: BENEFICIAL MICROBES. 2011;2(1):79-90
Safety and persistence of orally administered human Lactobacillus sp strains in healthy adults
Huett P; Koll P; Stsepetova J; Alvarez B; Maendar R; Krogh-Andersen K; Marcotte H; Hammarstroem L; Mikelsaar M
Review: MOLECULAR MEDICINE. 2011;17(11-12):1383-1396
Selective IgA Deficiency in Autoimmune Diseases
Wang N; Shen N; Vyse TJ; Anand V; Gunnarson I; Sturfelt G; Rantapaa-Dahlqvist S; Elvin K; Truedsson L; Andersson BA; Dahle C; Ortqvist E; Gregersen PK; Behrens TW; Hammarstrom L
Letter: JOURNAL OF IMMUNOLOGY. 2009;182(8):4495-4496
Comment on "Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching"
Sekine H; Ferreira RC; Pan-Hammarstrom Q; Hammarstrom L; Gilkeson GS; Behrens TW
Corrigendum: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY. 2009;19(5):422
Isolated Growth Hormone Deficiency in a Patient with Immunoglobulin Class Switch Recombination Deficiency (vol 19, pg 233, 2009)
Kashef S; Ghaedian MM; Rezaei N; Karamizadeh Z; Aghamohammadi A; Durandy A; Pan-Hammarstrom Q; Hammarstrom L
Meeting abstract: CLINICAL IMMUNOLOGY. 2009;131:S123
Human BAFF-R Deficiency is Associated with Primary Antibody Deficiency Syndrome
Kienzler A-K; Salzer U; Warnatz K; Grimbacher B; Rolink A; Pan-Hammarstrom Q; Hammarstrom L; Peter HH; Eibel H
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(2):327-333
Antibody deficiency diseases
Pan-Hammarstrom Q; Hammarstrom L
Review: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2008;147(2):87-92
Progression of selective IgA deficiency to common variable immunodeficiency
Aghamohammadi A; Mohammadi J; Parvaneh N; Rezaei N; Moin M; Espanol T; Hammarstrom L
Other: IMMUNOLOGICAL REVIEWS. 2008;224:5-6
Goran!Moller, MD, PhD, 1936-2008 -: Obituary
Smith CIE; Hammarstrom L
Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;120(4):776-794
Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee.
Geha RS; Notarangelo LD; Casanova J-L; Chapel H; Conley ME; Fischer A; Hammarström L; Nonoyama S; Ochs HD; Puck JM; Roifman C; Seger R; Wedgwood J; International Union of Immunological Societies Pri
Letter: NATURE GENETICS. 2007;39(4):429-430
Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency
Pan-Hammarstrom Q; Salzer U; Du L; Bjorkander J; Cunningham-Rundles C; Nelson DL; Bacchelli C; Gaspar HB; Offer S; Behrens TW; Grimbacher B; Hammarstrom L
Review: ADVANCES IN IMMUNOLOGY. 2007;93:1-61
Class switch recombination:: A comparison between mouse and human
Pan-Hammarstrom Q; Zhao Y; Hammarstrom L
Review: JOURNAL OF INTERNAL MEDICINE. 2006;260(6):509-516
Intravenous polyclonal IgM-enriched immunoglobulin therapy in sepsis:: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis
Norrby-Teglund A; Haque KN; Hammarstrom L
Published conference paper: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 2005;108(1-2):145-150
Isolation of the gene encoding the bovine neonatal Fc receptor
Doleschall M; Zhao YF; Mayer B; Hammarström L; Kacskovics I
Letter: JOURNAL OF IMMUNOLOGY. 2004;172(5):2727
Lack of association between human switch recombination breakpoints and the secondary structure of targeted DNA regions
Pan-Hammarström Q; Zhao YF; Hammarström L
Published conference paper: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. 2002;87(3-4):327-330
Localization of the sheep FcRn in the mammary gland
Mayer B; Zolnai A; Frenyó LV; Jancsik V; Szentirmay Z; Hammarström L; Kacskovics I
Letter: NATURE IMMUNOLOGY. 2002;3(7):595
Lack of IgA in Cμ-deficient patients
Pan Q; Matamoros N; Björkander J; Conley ME; Hammarström L
Letter: VOX SANGUINIS. 2002;82(2):84-85
Regarding 'Rapid detection of antibodies to immunoglobulin A molecules by using the particle gel immunoassay' by Salama et al.
Pan Q; Hammarström L
Review: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;120(2):225-231
Selective IgA deficiency (SIgAD) and common variable immunodeficiency (CVID).
Hammarström L; Vorechovsky I; Webster D
Review: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;116(2):193-205
Passive immunity against human pathogens using bovine antibodies
Weiner C; Pan Q; Hurtig M; Borén T; Bostwick E; Hammarström L
Review: ADVANCES IN GENETICS. 2001;43:103-188
Primary immunodeficiency mutation databases
Vihinen M; Arredondo-Vega FX; Casanova JL; Etzioni A; Giliani S; Hammarström L; Hershfield MS; Heyworth PG; Hsu AP; Lähdesmäki A; Lappalainen I; Notarangelo LD; Puck JM; Reith W; Roos D; Schumacher RF; Schwarz K; Vezzoni P; Villa A; Väliaho J; Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2000;178:99-110
Molecular basis of IgG subclass deficiency
Pan Q; Hammarström L
Meeting abstract: EUROPEAN JOURNAL OF CANCER. 1999;35:s302
The role of ATM gene in cancer predisposition
Borresen-Dale AL; Hahnemann J; Hammerström L; Kleinerman R; Kääriänen H; Laake K; Olsen JH; Sankila R; Tretli S; Tucker M
Published conference paper: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS, SUPPLEMENT. 1999;88(430):127-132
Passive immunity against rotavirus in infants.
Hammarström L
Meeting abstract: TRANSPLANTATION. 1999;67(7):S144
Fungal prophylaxis by oral administration of bovine anti-Candida antibodies in allogeneic BMT
Tollemar J; Gross N; Torner P; Jarstrand C; Hammarstrom L; Ringdén O
Letter: THE LANCET. 1998;352(9142):1786
Ischaemic heart disease in primary immunodeficiency
Hammar N; Linnersjö A; Hansson GK; Björkander J; Hammarström L
Meeting abstract: MOLECULAR IMMUNOLOGY. 1998;35(11-12):722
Role of the 3' immunoglobulin gene enhancer in immunodeficiency patients
Pan Q; Huang P; Mills FC; Hammarström L
Meeting abstract: MOLECULAR IMMUNOLOGY. 1998;35(11-12):675
Genetic linkage of IgA deficiency to the MHC:: Evidence for allele segregation distortion at IGAD1 and parent-of-origin penetrance differences
Vorechovsky I; Plebani A; Webster ADB; Hammarstrom L
Meeting abstract: MOLECULAR IMMUNOLOGY. 1998;35(11-12):645-647
Report from the ESID registry of primary immunodeficiencies -: July 1998
Abedi MR; Morgan G; Goii H; Paganelli R; Matamoros N; Hammarström L
Published conference paper: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 1998;17(5):367-372
Intranasally administered immunoglobulin for the prevention of rhinitis in children.
Heikkinen T; Ruohola A; Ruuskanen O; Waris M; Uhari M; Hammarström L
Letter: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 1997;41(10):2320
Survival of immunoglobulins from different species through the gastrointestinal tract in healthy adult volunteers: Implications for human therapy
Bogstedt AK; Hammarstrom L; Robertson AK
Letter: NATURE GENETICS. 1997;17(1):96-99
Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia
Vorechovsky I; Luo LP; Dyer MJS; Catovsky D; Amlot PL; Yaxley JC; Foroni L; Hammarstrom L; Webster ADB; Yuille MAR
Review: APMIS. 1995;103(12):833-842
Genetics of IgA deficiency
Truedsson L; Baskin B; Pan Q; Rabbani H; Vorechovsky I; Smith CIE; Hammarstrom L
Published conference paper: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. 1995;76(3):S214-S218
THE INFLUENCE OF GENE DELETIONS AND DUPLICATIONS WITHIN THE IGHC LOCUS ON SERUM IMMUNOGLOBULIN SUBCLASS LEVELS
RABBANI H; KONDO N; SMITH CIE; HAMMARSTROM L
Editorial comment: ANNALS OF MEDICINE. 1995;27(4):477-479
POSITIONAL CLONING AND THE MOLECULAR-BASIS OF IMMUNODEFICIENCY
SMITH CIE; HAMMARSTROM L
Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 1995;84(4):463-464
Prophylaxis of Candida infections in transplanted patients.
Hammarström L
Meeting abstract: GASTROENTEROLOGY. 1995;108(4):A792
ORAL IGA TREATMENT OF CHRONIC NONSPECIFIC DIARRHEA IN INFANTS AND CHILDREN
CASSWALL TH; HAMMARSTROM L; BOGSTEDT A; NORD CE; VERESS B; BROCKSTEDT U; DAHLSTROM KA
Letter: THE LANCET. 1995;345(8946):382-383
SUBCUTANEOUS GAMMA-GLOBULIN FOR PATIENTS WITH SECONDARY HYPOGAMMAGLOBULINEMIA
HAMMARSTROM L; SAMUELSSON J; GRIMFORS G
Other: IMMUNOGENETICS. 1995;42(2):149-152
THE PAX5 GENE - A LINKAGE AND MUTATION ANALYSIS IN CANDIDATE HUMAN PRIMARY IMMUNODEFICIENCIES
VORECHOVSKY I; KOSKINEN S; PAGANELLI R; SMITH CIE; BUSSLINGER M; HAMMARSTROM L
Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 1995;27(4):303-313
CHARACTERIZATION OF HAEMOPHILUS-INFLUENZAE ISOLATES FROM THE RESPIRATORY-TRACT OF PATIENTS WITH PRIMARY ANTIBODY DEFICIENCIES - EVIDENCE FOR PERSISTENT COLONIZATIONS
SAMUELSON A; BORRELLI S; GUSTAFSON R; HAMMARSTROM L; SMITH CIE; JONASSON J; LINDBERG AA
Review: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1995;371A:9-13
In vivo switching: identification of germline transcripts for human IgA.
Smith CI; Baskin B; Pattersson E; Hammarstrom L; Islam KB
Other: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES. 1995;14(1):61-64
LACK OF EFFECT OF ORALLY-ADMINISTERED HUMAN SERUM IMMUNOGLOBULIN ON THE NORMAL HUMAN ORAL AND INTESTINAL MICROFLORA
BOGSTEDT AK; NORD CE; HAMMARSTROM L
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Professor, Senior, Medicinsk biokemi och biofysik, Karolinska Institutet, 2024-2025
Professor, Medicinsk biokemi och biofysik, Karolinska Institutet, 2023-2024

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