Lena Karlsson

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Docent och universitetslektor i Cariologi. Undervisar på grundutbildningen
tandhygienist- och tandläkarprogrammet samt forskar inom ämnesområdet
Cariologi.
Disputerade 2009 med en avhandling om optiska metoder i kariesdiagnostiken
”Optical based technologies for detection of dental caries”. Olika
optiska instrument i kariesdiagnostiken innebär att man med olika
våglängdsområden kan belysa tand och kariesangrepp och kvantifiera
skillnader mellan frisk-sjuk vävnad. Oftast finner man ett kariesangrepp på
ett mycket tidigt stadium, innan ögat eller några av våra vanligt
förekommande undersökningsmetoder finner karies. Eftersom man lyser på
tanden med icke-hälsovådliga strålar kan man upprepa undersökningen om
och om igen och med korta intervaller.
Optiska metoder i kariesdiagnostiken innebär att vi bl. a har undersökt
olika våglängdsområden och vilka som lämpar sig bäst att använda om vi
vill finna karies i tandens olika vävnader. Optiska metoder kan också
användas för att utvärdera olika förebyggande åtgärder i
kariessjukdomen, t ex om vi vill testa en ny tandkräm, probiotika
eller ozon. Metoderna går också att använda om man vill utvärdera
olika behandlingsstrategier som är mest effektiva att förebygga sjukdom.
Övrig forskning och samarbete med andra forskargrupper vid
Karolinska Institutet och Danderyds sjukhus syftar till att undersöka
om en fetmaoperation kan påverka munhälsa.
Ett annat samarbete är med Umeå universitet där forskning pågår om
huruvida genetiska defekter i immunsystemet kan kopplas till varför vissa
barn får mer svårbehandlad karies.

Artiklar

Article: ORAL DISEASES. 2024;30(3):1643-1651
Metabolic surgery and oral health: A register-based study
Marsk R; Freedman F; Yan J; Karlsson L; Sandborgh-Englund G
Article: PHYSIOLOGICAL REPORTS. 2023;11(22):e15886
Effect of controlled hypotensive hemorrhage on plasma sodium levels in anesthetized pigs: An exploratory study
Krmar RT; Franzen S; Karlsson L; Strandberg H; Tornroth-Horsefield S; Andresen JK; Jensen BL; Carlstrom M; Frithiof R
Journal article: 2023
Adrenals
Lajic S; Paltoglou G; Karlsson L; Charmandari E
Article: CORTEX. 2023;159:1-15
Brain activity during visuospatial working memory in congenital adrenal hyperplasia
van't Westeinde A; Zimmermann M; Messina V; Karlsson L; Padilla N; Lajic S
Journal article: 2022
Adrenals
Lajic S; Paltoglou G; Karlsson L; Charmandari E
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2022;107(6):E2481-E2487
Ambulatory Blood Pressure Monitoring in Children and Adults Prenatally Exposed to Dexamethasone Treatment
Karlsson L; Wallensteen L; Nordenstrom A; Krmar RT; Lajic S
Journal article: 2021
Adrenals
Lajic S; Karlsson L; Paltoglou G; Charmandari E
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(11):e4074-e4082
First Trimester DEX Treatment Is Not Associated with Altered Brain Activity During Working Memory Performance in Adults
van't Westeinde A; Zimmermann M; Messina V; Karlsson L; Padilla N; Lajic S
Journal article: 2020
Adrenals
Lajic S; Karlsson L; Paltoglou G; Charmandari E
Article: INTERNATIONAL JOURNAL OF NEONATAL SCREENING. 2020;6(3):E71-71
Update on the Swedish Newborn Screening for Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
Zetterstrom RH; Karlsson L; Falhammar H; Lajic S; Nordenstrom A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(8):2575-2586
First-Trimester Prenatal Dexamethasone Treatment Is Associated With Alterations in Brain Structure at Adult Age
van't Westeinde A; Karlsson L; Nordenstrom A; Padilla N; Lajic S
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020;201:105699
Genome-wide investigation of DNA methylation in congenital adrenal hyperplasia
Karlsson L; Barbaro M; Ewing E; Gomez-Cabrero D; Lajic S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(7):e2439-e2448
Perturbed Beta-Cell Function and Lipid Profile After Early Prenatal Dexamethasone Exposure in Individuals Without CAH
Wallensteen L; Karlsson L; Messina V; Nordenstrom A; Lajic S
Article: CEREBRAL CORTEX. 2020;30(5):2777-2788
Altered Gray Matter Structure and White Matter Microstructure in Patients with Congenital Adrenal Hyperplasia: Relevance for Working Memory Performance
van't Westeinde A; Karlsson L; Sandberg MT; Nordenstrom A; Padilla N; Lajic S
Article: ENDOCRINE. 2020;68(2):427-437
Good overall behavioural adjustment in children and adolescents with classic congenital adrenal hyperplasia
Messina V; Hirvikoski T; Karlsson L; Vissani S; Wallensteen L; Ortolano R; Balsamo A; Nordenstrom A; Lajic S
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(3):E683-E691
Cognitive Function of Children and Adolescents With Congenital Adrenal Hyperplasia: Importance of Early Diagnosis
Messina V; Karlsson L; Hirvikoski T; Nordenstrom A; Lajic S
Article: CLINICAL BIOCHEMISTRY. 2019;73:50-56
Novel non-classic CYP21A2 variants, including combined alleles, identified in patients with congenital adrenal hyperplasia
Karlsson L; Michelatto DDP; Gori Lusa AL; Mgnani Silva CD; Ostberg LJ; Persson B; Guerra-Junior G; Valente de Lemos-Marini SH; Baldazzi L; Menabo S; Balsamo A; Greggio NA; de Mello MP; Barbaro M; Lajic S
Journal article: 2019
Adrenals
Lajic S; Karlsson L; Charmandari E
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2019;3(1):250-263
Epigenetic Alterations Associated With Early Prenatal Dexamethasone Treatment
Karlsson L; Barbaro M; Ewing E; Gomez-Cabrero D; Lajic S
Article: CLINICAL AND EXPERIMENTAL DENTAL RESEARCH. 2018;4(6):230-240
Perceived oral health in patients after bariatric surgery using oral health-related quality of life measures
Karlsson L; Carlsson J; Jenneborg K; Kjaeldgaard M
Article: PSYCHONEUROENDOCRINOLOGY. 2018;91:68-74
Prenatal dexamethasone treatment in the context of at risk CAH pregnancies: Long-term behavioral and cognitive outcome
Karlsson L; Nordenstrom A; Hirvikoski T; Lajic S
Article: HORMONES AND BEHAVIOR. 2018;98:219-224
Evaluation of behavioral problems after prenatal dexamethasone treatment in Swedish children and adolescents at risk of congenital adrenal hyperplasia
Wallensteen L; Karlsson L; Messina V; Gezelius A; Sandberg MT; Nordenstrom A; Hirvikoski T; Lajic S
Article: STEM CELLS INTERNATIONAL. 2018;2018:7127042-9
Laminin 521 Stabilizes the Pluripotency Expression Pattern of Human Embryonic Stem Cells Initially Derived on Feeder Cells
Albalushi H; Kurek M; Karlsson L; Landreh L; Kjartansdottir KR; Soder O; Hovatta O; Stukenborg J-B
Article: CLINICAL ENDOCRINOLOGY. 2017;87(6):651-659
Cognitive impairment in adolescents and adults with congenital adrenal hyperplasia
Karlsson L; Gezelius A; Nordenstrom A; Hirvikoski T; Lajic S
Article: JOURNAL OF BIOPHOTONICS. 2016;9(6):596-602
Evaluation of dental enamel caries assessment using Quantitative Light Induced Fluorescence and Optical Coherence Tomography
Araujo Maia AM; de Freitas AZ; Campello SDL; Leonidas Gomes AS; Karlsson L
Article: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY. 2016;2016:4209670-10
Functional and Structural Consequences of Nine CYP21A2 Mutations Ranging from Very Mild to Severe Effects
Michelatto DDP; Karlsson L; Gori Lusa AL; Mgnani Silva CD; Ostberg LJ; Persson B; Guerra-Junior G; Valente de Lemos-Marini SH; Barbaro M; de Mello MP; Lajic S
Article: BENEFICIAL MICROBES. 2014;5(4):403-407
Effect of tablets containing probiotic bacteria (Lactobacillus reuteri) on early caries lesions in adolescents: a pilot study
Keller MK; Larsen IN; Karlsson L; Twetman S
Article: CLINICAL ORAL INVESTIGATIONS. 2014;18(7):1785-1792
Treatment effect of ozone and fluoride varnish application on occlusal caries in primary molars: a 12-month study
Johansson E; van Dijken JWV; Karlsson L; Andersson-Wenckert I
Article: SEXUAL DEVELOPMENT. 2014;8(4):146-150
No Mutations in the PSMC3IP Gene Identified in a Swedish Cohort of Women with Primary Ovarian Insufficiency
Norling A; Hirschberg AL; Karlsson L; Rodriguez-Wallberg KA; Iwarsson E; Wedell A; Barbaro M
Article: ACTA ODONTOLOGICA SCANDINAVICA. 2013;71(3-4):464-468
Effect of fluoridated milk on enamel demineralization adjacent to fixed orthodontic appliances
Skold-Larsson K; Sollenius O; Karlsson L; Petersson LG; Twetman S
Article: ACTA ODONTOLOGICA SCANDINAVICA. 2013;71(3-4):676-682
Approximal caries increment in adolescents after a visual aid in combination with a comprehensive open discussion
Haggblom A; Naimi-Akbar A; Lith A; Karlsson L
Article: MICROSCOPY RESEARCH AND TECHNIQUE. 2012;75(5):605-608
Comparison among gold standard techniques used for the validation of methods for occlusal caries detection
Rodrigues JA; Neuhaus KW; Diniz MB; Hug I; Stich H; Karlsson L; Lussi A
Article: DENTOMAXILLOFACIAL RADIOLOGY. 2011;40(7):429-433
Evaluation of two imaging techniques: near-infrared transillumination and dental radiographs for the detection of early approximal enamel caries
Maia AMA; Karlsson L; Margulis W; Gomes ASL
Article: CLINICAL ORAL INVESTIGATIONS. 2011;15(3):369-373
Treatment of post-orthodontic white spot lesions with casein phosphopeptide-stabilised amorphous calcium phosphate
Broechner A; Christensen C; Kristensen B; Tranaeus S; Karlsson L; Sonnesen L; Twetman S
Article: ACTA ODONTOLOGICA SCANDINAVICA. 2010;68(6):323-328
Combination of high-fluoride toothpaste and no post-brushing water rinsing on enamel demineralization using an in-situ caries model with orthodontic bands
Al-Mulla A; Karlsson L; Kharsa S; Kjellberg H; Birkhed D
Article: JOURNAL OF BIOMEDICAL OPTICS. 2010;15(3):036001
Near-infrared transillumination of teeth: measurement of a system performance
Karlsson L; Maia AMA; Kyotoku BBC; Tranaeus S; Gomes ASL; Margulis W
Article: ACTA ODONTOLOGICA SCANDINAVICA. 2010;68(3):148-153
DIAGNOdent measurements of cultures of selected oral bacteria and demineralized enamel
Astvaldsdottir A; Tranaeus S; Karlsson L; Holbrook WP
Article: INTERNATIONAL JOURNAL OF DENTISTRY. 2010;2010:270729-9
Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue.
Karlsson L
Article: CARIES RESEARCH. 2009;43(5):397-404
Validity and Reliability of Laser-Induced Fluorescence Measurements on Carious Root Surfaces in vitro
Karlsson L; Johansson E; Tranaeus S
Article: ACTA ODONTOLOGICA SCANDINAVICA. 2007;65(5):284-291
Effect of supplementary amine fluoride gel in caries-active adolescents.: A clinical QLF study
Karlsson L; Lindgren L-E; Trollsas K; Angmar-Mansson B; Tranaeus S
Article: SWEDISH DENTAL JOURNAL. SUPPLEMENT. 2004;28(4):173-182
In vivo validity and reliability of IR fluorescence measurements for caries detection and quantification
Tranæus S; Lindgren LE; Karlsson L; Angmar-Månsson B
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Alla övriga publikationer

Review: ENDOCRINE CONNECTIONS. 2023;12(4):e220400
An update on the long-term outcomes of prenatal dexamethasone treatment in congenital adrenal hyperplasia
Van't Westeinde A; Karlsson L; Messina V; Wallensteen L; Brosamle M; Dal Maso G; Lazzerini A; Kristensen J; Kwast D; Tschaidse L; Auer MK; Nowotny HF; Persani L; Reisch N; Lajic S
Review: INTERNATIONAL JOURNAL OF NEONATAL SCREENING. 2020;6(3):68
The Success of a Screening Program Is Largely Dependent on Close Collaboration between the Laboratory and the Clinical Follow-Up of the Patients
Lajic S; Karlsson L; Zetterstrom RH; Falhammar H; Nordenstrom A
Preprint: MEDRXIV. 2019
Genome-wide investigation of DNA methylation in congenital adrenal hyperplasia
Karlsson L; Barbaro M; Ewing E; Gomez-Cabrero D; Lajic S
Review: HORMONE RESEARCH IN PAEDIATRICS. 2018;89(5):362-371
Prenatal Treatment of Congenital Adrenal Hyperplasia: Long-Term Effects of Excess Glucocorticoid Exposure
Lajic S; Karlsson L; Nordenstrom A
Editorial comment: OPEN DENTISTRY JOURNAL. 2017;11:65-70
Ozone Treatment on Dentin Hypersensitivity Surfaces - A Pilot Study.
Lena K; Marianne K
Thesis / dissertation: 2009
Optical based technologies for detection of dental caries
Karlsson, Lena

Anställningar

Lektor, Odontologi, Karolinska Institutet, 2011-

Examina och utbildning

Docent, Odontologi, Karolinska Institutet, 2021
Medicine Doktorsexamen, Institutionen för odontologi, Karolinska Institutet, 2009
Medicine Kandidatexamen, Karolinska Institutet, 2004
Tandhygienistexamen, Karolinska Institutet, 2003

Om mig

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI