Lena Hjelte

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: JOURNAL OF CYSTIC FIBROSIS. 2025;24(4):691-697
Cannabinoid receptor 2 agonist, lenabasum, for the treatment of pulmonary exacerbations in cystic fibrosis
West NE; Konstan MW; Flume PA; VanDevanter DR; Magaret A; Mazurek H; Amelina EL; Laki I; Chiron R; Sutharsan S; Columbo C; Dorkin HL; Downey DG; Sole A; Hjelte L; Tullis E; Dgetluck N; Dinh Q; Constantine S; White B; Elborn JS; Chmiel JF
Article: THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE. 2024;18:17534666241254090
Impact of lumacaftor/ivacaftor on the bacterial and fungal respiratory pathogens in cystic fibrosis: a prospective multicenter cohort study in Sweden
Al Shakirchi M; Sorjonen K; Hjelte L; Klingspor L; Bergman P; Ericson P; Svedberg M; Lindberg U; Hansen C; de Monestrol I
Article: ISCIENCE. 2022;25(10):105070
Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination
Stone VM; Utorova R; Butrym M; Sioofy-Khojine A-B; Hankaniemi MM; Ringqvist EE; Blanter M; Parajuli A; Pincikova T; Fischler B; Karpati F; Hytonen VP; Hyoty H; Hjelte L; Flodstrom-Tullberg M
Article: RESPIRATORY RESEARCH. 2022;23(1):127
MAIT cell counts are associated with the risk of hospitalization in COPD
Pincikova T; Parrot T; Hjelte L; Hogman M; Lisspers K; Stallberg B; Janson C; Malinovschi A; Sandberg JK
Article: JOURNAL OF FUNGI. 2021;7(11):944
The Effects of Aspergillus fumigatus Colonization on Lung Function in Patients with Cystic Fibrosis
Al Shakirchi M; Sorjonen K; Klingspor L; Bergman P; Hjelte L; de Monestrol I
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2020;96:663-670
A 16-year retrospective study on fungal prevalence and diversity in patients with cystic fibrosis: Candida dubliniensis was associated with a decline in lung function
Al Shakirchi M; Klingspor L; Bergman P; Hjelte L; de Monestrol I
Article: CHEST. 2018;153(5):e93-e96
Severely Impaired Control of Bacterial Infections in a Patient With Cystic Fibrosis Defective in Mucosal-Associated Invariant T Cells.
Pincikova T; Paquin-Proulx D; Moll M; Flodström-Tullberg M; Hjelte L; Sandberg JK
Article: JOURNAL OF INFECTIOUS DISEASES. 2017;216(10):1308-1317
A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense
Svedin E; Utorova R; Huhn MH; Larsson PG; Stone VM; Garimella M; Lind K; Hagglof T; Pincikova T; Laitinen OH; McInerney GM; Scholte B; Hjelte L; Karlsson MCI; Flodstrom-Tullberg M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2017;189(3):359-371
Vitamin D treatment modulates immune activation in cystic fibrosis
Pincikova T; Paquin-Proulx D; Sandberg JK; Flodstrom-Tullberg M; Hjelte L
Article: PHYSIOTHERAPY RESEARCH INTERNATIONAL. 2017;22(3):e1667
Non-invasive Ventilation as Airway Clearance Technique in Cystic Fibrosis
Hortal MCR; Nygren-Bonnier M; Hjelte L
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2017;71(2):203-205
Clinical impact of vitamin D treatment in cystic fibrosis: a pilot randomized, controlled trial
Pincikova T; Paquin-Proulx D; Sandberg JK; Flodstrom-Tullberg M; Hjelte L
Article: UPSALA JOURNAL OF MEDICAL SCIENCES. 2017;122(1):61-66
Psychometric evaluation of the Swedish translation of the revised Cystic Fibrosis Questionnaire in adults
Hochwalder J; Brucefors AB; Hjelte L
Article: ACTA PAEDIATRICA. 2016;105(7):851-853
Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D
Pincikova T; Svedin E; Domsgen E; Flodstrom-Tullberg M; Hjelte L
Article: BMJ OPEN RESPIRATORY RESEARCH. 2016;3(1):e000141
Associations between genetics, medical status, physical exercise and psychological well-being in adults with cystic fibrosis
Backstrom-Eriksson L; Bergsten-Brucefors A; Hjelte L; Melin B; Sorjonen K
Article: BMC PULMONARY MEDICINE. 2015;15:121
Anxiety and depression in adults with cystic fibrosis: a comparison between patients and the general population in Sweden and three other European countries
Backstrom-Eriksson L; Sorjonen K; Bergsten-Brucefors A; Hjelte L; Melin B
Article: RESPIRATORY CARE. 2014;59(10):1537-1541
Time Point to Perform Lung Function Tests Evaluating the Effects of an Airway Clearance Therapy Session in Cystic Fibrosis
Hortal MCR; Hjelte L
Article: JOURNAL OF CYSTIC FIBROSIS. 2014;13(1):24-28
Nasal potential difference measurements in diagnosis of cystic fibrosis: An international survey
Naehrlich L; Ballmann M; Davies J; Derichs N; Gonska T; Hjelte L; van Konigsbruggen-Rietschel S; Leal T; Melotti P; Middleton P; Tuemmler B; Vermeulen F; Wilschanski M
Article: DIABETOLOGIA. 2011;54(12):3007-3015
Vitamin D deficiency as a risk factor for cystic fibrosis-related diabetes in the Scandinavian Cystic Fibrosis Nutritional Study
Pincikova T; Nilsson K; Moen IE; Fluge G; Hollsing A; Knudsen PK; Lindblad A; Mared L; Pressler T; Hjelte L
Article: SCANDINAVIAN JOURNAL OF CARING SCIENCES. 2011;25(2):365-372
Mental health and sense of coherence among Swedish adults with cystic fibrosis
Brucefors AB; Hjelte L; Hochwalder J
Article: JOURNAL OF CYSTIC FIBROSIS. 2011;10 Suppl 2:S79-S81
Pulmonary exacerbation: towards a definition for use in clinical trials. Report from the EuroCareCF Working Group on outcome parameters in clinical trials.
Bilton D; Canny G; Conway S; Dumcius S; Hjelte L; Proesmans M; Tümmler B; Vavrova V; De Boeck K
Article: JOURNAL OF CYSTIC FIBROSIS. 2011;10:S75-S78
Chronic Pseudomonas aeruginosa infection definition: EuroCareCF Working Group report
Pressler T; Bohmova C; Conway S; Dumcius S; Hjelte L; Hoiby N; Kollberg H; Tuemmler B; Vavrova V
Article: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. 2011;25(3):298-305
Age at diagnosis and disease progression of cystic fibrosis in an area without newborn screening
de Monestrol I; Klint A; Sparen P; Hjelte L
Article: EXPERIMENTAL AND MOLECULAR PATHOLOGY. 2011;90(1):79-83
The effect of S-nitrosoglutathione and L-cysteine on chloride efflux from cystic fibrosis airway epithelial cells
Servetnyk Z; Jiang S; Hjelte L; Gaston B; Roomans GM; Dragomir A
Article: ACTA PAEDIATRICA. 2011;100(2):209-215
Parental support for newborn screening for cystic fibrosis
de Monestrol I; Brucefors AB; Sjoberg B; Hjelte L
Article: FOOD & NUTRITION RESEARCH. 2011;55:7561
Dietary intake and nutritional status in a Scandinavian adult cystic fibrosis-population compared with recommendations
Moen IE; Nilsson K; Andersson A; Fagerland MW; Fluge G; Hollsing A; Gilljam M; Mared L; Pressler T; Santi H; Storrosten O-T; Hjelte L
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2011;65(1):102-109
Inverse relation between vitamin D and serum total immunoglobulin G in the Scandinavian Cystic Fibrosis Nutritional Study
Pincikova T; Nilsson K; Moen IE; Karpati F; Fluge G; Hollsing A; Knudsen PK; Lindblad A; Mared L; Pressler T; Hjelte L
Article: PEDIATRIC PULMONOLOGY. 2010;45(10):959-965
Gender Differences in the Scandinavian Cystic Fibrosis Population
Olesen HV; Pressler T; Hjelte L; Mared L; Lindblad A; Knudsen PK; Laerum BN; Johannesson M
Article: HUMAN MUTATION. 2009;30(7):1093-1103
Mutations in the Amiloride-Sensitive Epithelial Sodium Channel in Patients With Cystic Fibrosis-Like Disease
Azad AK; Rauh R; Vermeulen F; Jaspers M; Korbmacher J; Boissier B; Bassinet L; Fichou Y; des Georges M; Stanke F; De Boeck K; Dupont L; Balascakova M; Hjelte L; Lebecque P; Radojkovic D; Castellani C; Schwartz M; Stuhrmann M; Schwarz M; Skalicka V; de Monestrol I; Girodon E; Ferec C; Claustres M; Tuemmler B; Cassiman J-J; Korbmacher C; Cuppens H
Article: JOURNAL OF CYSTIC FIBROSIS. 2009;8(3):198-202
Co-morbidity of cystic fibrosis and celiac disease in Scandinavian cystic fibrosis patients
Fluge G; Olesen HV; Gilljam M; Meyer P; Pressler T; Storrosten OT; Karpati F; Hjelte L
Article: JOURNAL OF CYSTIC FIBROSIS. 2009;8(1):37-42
Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods
Pressler T; Karpati F; Granstrom M; Knudsen PK; Lindblad A; Hjelte L; Olesen HV; Meyer P; Hoiby N
Article: BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. 2008;51(Pt 4):153-157
Chitosan as a carrier for non-viral gene transfer in a cystic-fibrosis cell line
Nydert P; Dragomir A; Hjelte L
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2008;47(5):547-554
Expression of Intestinal and Lung Alkaline Sphingomyelinase and Neutral Ceramidase in Cystic Fibrosis F508del Transgenic Mice
Ohlsson L; Hjelte L; Huhn M; Scholte BJ; Wilke M; Flodstrom-Tullberg M; Nilsson A
Article: EPILEPSY RESEARCH. 2007;73(2):199-207
Plasma phospholipid fatty acids are influenced by a ketogenic diet enriched with n-3 fatty acids in children with epilepsy
Dahlin M; Hjelte L; Nilsson S; Amark P
Article: RESPIRATORY RESEARCH. 2006;7(1):124
Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione
Servetnyk Z; Krjukova J; Gaston B; Zaman K; Hjelte L; Roomans GM; Dragomir A
Article: RESPIRATORY RESEARCH. 2006;7(1):79
Long-term clearance from small airways in subjects with ciliary dysfunction
Lindstroem M; Falk R; Hjelte L; Philipson K; Svartengren M
Article: EUROPEAN RESPIRATORY JOURNAL. 2005;25(2):317-323
Long-term clearance from small airways in patients with cystic fibrosis
Lindström M; Camner P; Falk R; Hjelte L; Philipson K; Svartengren M
Article: LIFE SCIENCES. 2004;75(18):2203-2216
Heparin can improve the viability of transfected cystic fibrosis cell lines in vitro
Dragomir A; Hjelte L; Hagenfeldt L; Roomans GM
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004;322(2):447-451
Curcumin does not stimulate cAMP-mediated chloride transport in cystic fibrosis airway epithelial cells
Dragomir A; Björstad J; Hjelte L; Roomans GM
Article: ACTA PAEDIATRICA. 2003;92(8):910-915
Early chemotherapy for non-tuberculous mycobacterial infections in patients with cystic fibrosis
Forslöw U; Geborek A; Hjelte L; Petrini B; Heurlin N
Article: CLINICAL SCIENCE. 2002;103(4):417-424
Cystic fibrosis transmembrane conductance regulator (CFTR) activity in nasal epithelial cells from cystic fibrosis patients with severe genotypes.
Andersson C; Dragomir A; Hjelte L; Roomans GM
Article: PEDIATRIC PULMONOLOGY. 2002;33(6):483-491
Predictors of deterioration of lung function in cystic fibrosis
Schaedel C; de Monestrol I; Hjelte L; Johannesson M; Kornfält R; Lindblad A; Strandvik B; Wahlgren L; Holmberg L
Article: CHEST. 2002;121(1):40-47
Nasal polyps in cystic fibrosis - Clinical endoscopic study with nasal lavage fluid analysis
Henriksson G; Westrin KM; Karpati F; Wikström AC; Stierna P; Hjelte L
Article: JOURNAL OF MICROSCOPY. 2001;203(Pt 3):277-284
Assessment of chloride secretion in human nasal epithelial cells by X-ray microanalysis
Dragomir A; Andersson C; Åslund M; Hjelte L; Roomans GM
Article: APMIS. 2001;109(5):389-400
Arbitrarily primed PCR and sequencing of 16S rDNA for epidemiological typing and species identification of Burkholderia cepacia isolates from Swedish patients with cystic fibrosis reveal genetic heterogeneity
Karpati F; Giedraitis V; Thore M; Lindman R; Monstein HJ; Hjelte L; Jonasson J
Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2000;32(1):75-79
TNF-α and IL-8 in consecutive sputum samples from cystic fibrosis patients during antibiotic treatment
Karpati F; Hjelte L; Wretlind B
Article: JOURNAL OF HOSPITAL INFECTION. 2000;44(1):37-41
Low level of bacterial contamination of mist tents used in home treatment of cystic fibrosis patients
Jakobsson BM; Hjelte L; Nyström B
Article: CLINICAL GENETICS. 1999;56(4):318-322
Three common CFTR mutations should be included in a neonatal screening programme for cystic fibrosis in Sweden
Schaedel C; Hjelte L; de Monestrol I; Johannesson M; Kollberg H; Kornfält R; Holmberg L
Article: EUROPEAN RESPIRATORY JOURNAL. 1999;14(3):686-692
Pulmonary gas exchange in cystic fibrosis:: basal status and the effect of iv antibiotics and inhaled amiloride
Lagerstrand L; Hjelte L; Jorulf H
Article: HUMAN REPRODUCTION. 1998;13(8):2092-2097
Female patients with cystic fibrosis suffer from reproductive endocrinological disorders despite good clinical status
Johannesson M; Landgren BM; Csemiczky G; Hjelte L; Gottlieb C
Article: PATIENT EDUCATION AND COUNSELING. 1998;34(2):115-123
Cystic fibrosis through a female perspective: Psychosocial issues and information concerning puberty and motherhood
Johannesson M; Carlson M; Brucefors AB; Hjelte L
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1997;239(2):606-611
Polymorphic expression of multidrug resistance mRNA in lung parenchyma of nonpregnant and pregnant rats: A comparison to cystic fibrosis mRNA expression
Johannesson M; Nordqvist ACS; Bogdanovic N; Hjelte L; Schalling M
Article: JOURNAL OF HOSPITAL INFECTION. 1997;36(3):201-207
Low bacterial contamination of nebulizers in home treatment of cystic fibrosis patients
Jakobsson BM; Onnered AB; Hjelte L; Nystrom B
Article: NEUROREPORT. 1997;8(2):535-539
Cystic fibrosis mRNA expression in rat brain: Cerebral cortex and medial preoptic area
Johannesson M; Bogdanovic N; Nordqvist ACS; Hjelte L; Schalling M
Article: PEDIATRICS. 1997;99(1):29-34
Delayed puberty in girls with cystic fibrosis despite good clinical status
Johannesson M; Gottlieb C; Hjelte L
Article: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. 1996;56(3):219-227
Metabolism of orally fed [H-3]-eicosapentaenoic and [C-14]-arachidonic acid in essential fatty acid-deficient rats
Nilsson A; Hjelte L; Strandvik B
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Editorial comment: JOURNAL OF CYSTIC FIBROSIS. 2024;23(5):1027-1030
Clinical outcomes of two infants with cystic fibrosis, including presence of the vas deferens, born to a woman with cystic fibrosis taking CFTR modulators during both pregnancies
Kowalik A; Roberts E; Harris AH; Sund M; Wird S; Kvist O; Hjelte L
Published conference paper: JOURNAL OF CYSTIC FIBROSIS. 2011;10(3):187-192
Association between genotype and pulmonary phenotype in cystic fibrosis patients with severe mutations
Geborek A; Hjelte L
Published conference paper: THORAX. 2009;64(8):683-691
Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis
Goubau C; Wilschanski M; Skalicka V; Lebecque P; Southern KW; Sermet I; Munck A; Derichs N; Middleton PG; Hjelte L; Padoan R; Vasar M; De Boeck K
Letter: EPILEPSY RESEARCH. 2007;76(2-3):150-151
Response to Commentary on the effects of a ketogenic diet enriched with omega-3 polyunsaturated fatty acids on plasma phospholipid fatty acid profile in children with drug-resistant epilepsy
Dahlin M; Hjelte L; Nilsson A; Amarka P
Letter: ACTA PAEDIATRICA. 1995;84(10):1124
MORAXELLA-CATARRHALIS IN THE COLONIZATION OF PSEUDOMONAS-AERUGINOSA
HJELTE L; MALMBORG AS
Letter: JOURNAL OF PEDIATRICS. 1995;126(1):155-156
INCIDENCE OF LIVER-DISEASE IN PATIENTS WITH CYSTIC-FIBROSIS AND MECONIUM ILEUS
LINDBLAD A; STRANDVIK B; HJELTE L

Anställningar

Professor Emeritus/Emerita, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023-2026
Adjungerad Professor, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2011-2016

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