Lars Sävendahl

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

- Professor och Avdelningschef, Barnendokrinologi, Institutionen för Kvinnors och Barns Hälsa, Karolinska Institutet
- FoU-chef, Tema Barn-Astrid Lindgrens Barnsjukhus, Karolinska Universitetssjukhuset
- Överläkare, PF Barnendokrin och metabola sjukdomar, ME Högspecialiserad Barnmedicin, Karolinska Universitetssjukhuset

Utbildning
Läkarexamen (1986), Medicine doktor (1989), Leg läkare (1991), Barnläkare (1997), Professor i barnendokrinologi (2005)

Forskningsbeskrivning

Längdtillväxt sker i den så kallade tillväxtplattan som består av ett lager brosk i båda ändarna av de flesta benen i kroppen. Lars Sävendahls forskningsgrupp har utvecklat nya försöksmodeller och har därigenom lyckats visa hur längdtillväxten regleras på cellnivå. Forskningsresultaten omsättas till olika metoder att behandla barn och ungdomar med avvikande längdtillväxt.

Artiklar

Journal article: ENDOCRINE ABSTRACTS. 2024

Minimum data set for global monitoring of the safety and efficacy of growth hormone replacement in adults - an expert group recommendation

Ching CS; Ahmed F; Andrews D; M.K. BB; Luiz BC; Bryce J; Chen M; Clayton P; Fleseriu M; Gebauer J; Ho K; Otto JJ; Luo X; Miller B; Neggers S; Savendahl L; Schilbach K; J. SC; Takahashi Y; Vitali D; Yuen K; Hoffman A; Johannsson G
Article: PEDIATRIC RESEARCH. 2024;:1-12

Lithium rescues cultured rat metatarsals from dexamethasone-induced growth failure

Soucek O; Cinek O; Velentza L; Semjonov V; Bezdicka M; Zaman F; Savendahl L
Journal article: INDIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM. 2024;28(2):160-166

Standardization of Weightage Assigned to Different Segments of the Hand X-ray for Assessment of Bone Age by the Greulich-Pyle Method.

Oza C; Khadilkar AV; Goel P; Aeppli T; Mondkar S; Shah N; Lohiya N; Prasad HK; Patil P; More C; Kajale N; Khadilkar V; Sävendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2024;:1-8

Safety and Efficacy of Bilateral Epiphysiodesis Surgery to Reduce Final Height in Extremely Tall Adolescents: A Follow-Up Study

Aeppli TRJ; Benyi E; Wehtje H; Chrysis D; Saevendahl L
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2024;8(3):bvae009

Humanin Treatment Protects Against Venetoclax-Induced Bone Growth Retardation in Ex Vivo Cultured Rat Bones

Velentza L; Wickstrom M; Kogner P; Ohlsson C; Zaman F; Saevendahl L
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2024;8(3):bvae009

Humanin Treatment Protects Against Venetoclax-Induced Bone Growth Retardation in Ex Vivo Cultured Rat Bones.

Velentza L; Wickström M; Kogner P; Ohlsson C; Zaman F; Sävendahl L
Article: FRONTIERS IN ARTIFICIAL INTELLIGENCE. 2024;7:1326488

The automated Greulich and Pyle: a coming-of-age for segmental methods?

Chapke R; Mondkar S; Oza C; Khadilkar V; Aeppli TRJ; Saevendahl L; Kajale N; Ladkat D; Khadilkar A; Goel P
Article: FRONTIERS IN ENDOCRINOLOGY. 2024;15:1360139

Long-term risk of neoplastic events after childhood growth hormone treatment: a population-based cohort study in Sweden

Tidblad A; Bottai M; Smedby KE; Albertsson-Wikland K; Saevendahl L
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2023;7(Supplement_1):bvad114.1417

THU166 A Minimum Data Set For The Monitoring Of Recombinant Human Growth Hormone (rhGH) Therapy In Children With Growth Hormone Deficiency (GHD)—A GloBE-Reg Initiative

Chen SC; Charmandari E; Choi J-H; Dou X; Gong C; Hamza R; Harvey J; Hoffman AR; Horikawa R; Johannsson G; Jorge AAL; Miller BS; Roehrich S; Savendahl LS; Tserotopolou X; Wajnrajch MP; Ahmed SF
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2023;7(Supplement_1):bvad114.487

SAT190 The Effect Of Mechanical Loading On Bone Growth Ex Vivo

Aeppli T; Zhang Z; Zaman F; Savendahl LS
Article: ANNALS OF BIOMEDICAL ENGINEERING. 2023;51(10):2229-2236

Micromechanical Loading Studies in Ex Vivo Cultured Embryonic Rat Bones Enabled by a Newly Developed Portable Loading Device

Zhang Z; Zaman F; Nava TS; Aeppli TRJ; Gutierrez-Farewik EM; Kulachenko A; Savendahl L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2023;108(10):2569-2578

Weekly Somapacitan in GH Deficiency: 4-Year Efficacy, Safety, and Treatment/Disease Burden Results From REAL 3

Savendahl L; Battelino T; Hojby Rasmussen M; Brod M; Rohrich S; Saenger P; Horikawa R
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2023;108(10):2653-2665

Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program

Backeljauw P; Blair JC; Ferran J-M; Kelepouris N; Miller BS; Pietropoli A; Polak M; Savendahl L; Verlinde F; Rohrer TR
Article: HORMONE RESEARCH IN PAEDIATRICS. 2023;97(4):365-373

Development of A Minimum Dataset for the Monitoring of Recombinant Human Growth Hormone (rhGH) Therapy Use in Children with Growth Hormone Deficiency (GHD) - A GloBE-Reg Initiative

Chen SC; Bryce J; Chen M; Charmandari E; Choi J-H; Dou X; Gong C; Hamza R; Harvey J; Hoffman AR; Horikawa R; Johannson G; Jorge AADL; Miller BS; Roehrich S; Saevendahl L; Tseretopoulou X; Vitali D; Wajnrajch M; Ahmed SF
Article: SCIENTIFIC REPORTS. 2023;13(1):8054

Pharmacological inhibition of BCL-2 with the FDA-approved drug venetoclax impairs longitudinal bone growth

Velentza L; Wickstrom M; Kogner P; Ohlsson C; Zaman F; Savendahl L
Article: BMJ OPEN DIABETES RESEARCH & CARE. 2023;11(2):e003303

Maternal depression or anxiety during pregnancy and offspring type 1 diabetes: a population-based family-design cohort study

Smew AI; Lundholm C; Gong T; Saevendahl L; Lichtenstein P; Brew BK; Almqvist C
Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1105602

The crosstalk between FGF21 and GH leads to weakened GH receptor signaling and IGF1 expression and is associated with growth failure in very preterm infants

Mistry JN; Silvennoinen S; Zaman F; Savendahl L; Mariniello K; Hall C; Howard SR; Dunkel L; Sankilampi U; Guasti L
Article: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1142310

A novel link between chronic inflammation and humanin regulation in children

Zhao Y; Makitie O; Laakso S; Fedosova V; Savendahl L; Zaman F
Article: SCIENTIFIC REPORTS. 2022;12(1):18189

TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner

Zhao Y; Celvin B; Denis MC; Karagianni N; Aulin C; Zaman F; Savendahl L
Journal article: BONE REPORTS. 2022;16:101360

Recovery from radiation-induced damage to growth plates involves functional compensation

Azar YM; Sävendahl L; Blomgren K; Newton PT
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2022;186(6):P35-P52

Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement

Boguszewski MCS; Boguszewski CL; Chemaitilly W; Cohen LE; Gebauer J; Higham C; Hoffman AR; Polak M; Yuen KCJ; Alos N; Antal Z; Bidlingmaier M; Biller BMK; Brabant G; Choong CSY; Cianfarani S; Clayton PE; Coutant R; Cardoso-Demartini AA; Fernandez A; Grimberg A; Gudmundsson K; Guevara-Aguirre J; Ho KKY; Horikawa R; Isidori AM; Jorgensen JOL; Kamenicky P; Karavitaki N; Kopchick JJ; Lodish M; Luo X; McCormack AI; Meacham L; Melmed S; Moab SM; Muller HL; Neggers SJCMM; Aguiar Oliveira MH; Ozono K; Pennisi PA; Popovic V; Radovick S; Savendahl L; Touraine P; van Santen HM; Johannsson G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2022;107(5):1357-1367

Effective GH Replacement With Once-weekly Somapacitan vs Daily GH in Children with GHD: 3-year Results From REAL 3

Savendahl L; Battelino T; Rasmussen MH; Brod M; Saenger P; Horikawa R
Article: BONE. 2022;154:116186

Radial shockwave treatment promotes chondrogenesis in human growth plate and longitudinal bone growth in rabbits

Ramesh S; Zaman F; Savendahl L; Madhuri V
Journal article: ANNALES D ENDOCRINOLOGIE. 2021;82(5):279-280

Somapacitan une injection par semaine versus une injection quotidienne en hormone de croissance dans le déficit en hormone de croissance : résultats d’efficacité sur 2 ans de REAL 3, un essai randomisé de phase 2

Sävendahl LS; Battelino T; Rasmussen MH; Horikawa R; Saenger P; Bovet J
Journal article: 2021

Association of childhood growth hormone treatment with long-term cardiovascular morbidity

A T; M B; H K; K A-W; L S
Journal article: 2021

Long-term safety of growth hormone treatment in childhood: two Large observational studies: nordiNet IOS and ANSWER

L S; M P; P B; JC B; BS M; TR R; A H-K; A P; N K; J R
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;106(6):1728-1741

Long-Term Safety of Growth Hormone Treatment in Childhood: Two Large Observational Studies: NordiNet IOS and ANSWER

Savendahl L; Polak M; Backeljauw P; Blair JC; Miller BS; Rohrer TR; Hokken-Koelega A; Pietropoli A; Kelepouris N; Ross J
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2021;5(Supplement_1):a680

Once-Weekly Somapacitan Versus Daily Growth Hormone in Growth Hormone Deficiency: 2-Year Efficacy Results From REAL 3, a Randomized Phase 2 Trial

Sävendahl LS; Battelino T; Rasmussen MH; Horikawa R; Saenger P
Article: JAMA PEDIATRICS. 2021;175(2):e205199

Association of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity

Tidblad A; Bottai M; Kieler H; Albertsson-Wikland K; Savendahl L
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:752756

Case Report: Bilateral Epiphysiodesis Due to Extreme Tall Stature in a Girl With a De Novo DNMT3A Variant Associated With Tatton-Brown-Rahman Syndrome

Lennartsson O; Lodefalk M; Wehtje H; Stattin E-L; Saevendahl L; Nilsson O
Article: SCIENTIFIC REPORTS. 2020;10(1):13400

Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bones

Ramesh S; Savendahl L; Madhuri V; Zaman F
Article: LANCET DIABETES & ENDOCRINOLOGY. 2020;8(8):683-692

Long-term mortality after childhood growth hormone treatment: the SAGhE cohort study

Savendahl L; Cooke R; Tidblad A; Beckers D; Butler G; Cianfarani S; Clayton P; Coste J; Hokken-Koelega ACS; Kiess W; Kuehni CE; Albertsson-Wikland K; Deodati A; Ecosse E; Gausche R; Giacomozzi C; Konrad D; Landier F; Pfaeffle R; Sommer G; Thomas M; Tollerfield S; Zandwijken GRJ; Carel J-C; Swerdlow AJ
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;70(6):853-857

Growth and Pubertal Timing in Boys With Adult-diagnosed Celiac Disease: A Population-based Longitudinal Cohort Study

Marild K; Ohlsson C; Bygdell M; Martikainen J; Savendahl L; Stordal K; Kindblom JM
Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2020;38(15_suppl):e13593

Can body size explain the excess cancer risk in men?

Radkiewicz C; Sjölander A; Benyi E; Lambe M; Dickman P; Sävendahl L; Edgren G
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2020;4(Supplement_1):sat-lb12

SAT-LB12 Once-Weekly Somapacitan vs Daily Growth Hormone in Growth Hormone Deficiency: 2-Year Safety Results From Real 3, a Randomized Phase 2 Trial

Savendahl LS; Rasmussen MH
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(4):dgz310-e1861

Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial

Savendahl L; Battelino T; Brod M; Rasmussen MH; Horikawa R; Juul RV; Saenger P
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2020;51(8):789-800

Adult height in patients with childhood-onset inflammatory bowel disease: a nationwide population-based cohort study

Mouratidou N; Malmborg P; Sachs MC; Askling J; Ekbom A; Neovius M; Smedby KE; Savendahl L; Ludvigsson JF; Olen O
Article: JAMA NETWORK OPEN. 2020;3(3):e200834

Familial Coaggregation of Asthma and Type 1 Diabetes in Children

Smew AI; Lundholm C; Savendahl L; Lichtenstein P; Almqvist C
Article: CLINICAL ORTHOPAEDICS AND RELATED RESEARCH. 2020;478(3):668-678

Radial Extracorporeal Shock Wave Treatment Promotes Bone Growth and Chondrogenesis in Cultured Fetal Rat Metatarsal Bones

Ramesh S; Zaman F; Madhuri V; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(6):380-395

Long-Term Effectiveness and Safety of Childhood Growth Hormone Treatment in Noonan Syndrome

Rohrer TR; Abuzzahab J; Backeljauw P; Birkegard AC; Blair J; Dahlgren J; Juliusson PB; Ostrow V; Pietropoli A; Polak M; Romano A; Ross J; Savendahl L; Miller BS
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(1):129-135

Humanin prevents undesired apoptosis of chondrocytes without interfering with the anti-inflammatory effect of dexamethasone in collagen-induced arthritis

Celvin B; Zaman F; Aulin C; Savendahl L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2019;104(10):4730-4742

Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet® IOS and ANSWER Program

Savendahl L; Polak M; Backeljauw P; Blair J; Miller BS; Rohrer TR; Pietropoli A; Ostrow V; Ross J
Journal article: 2019

Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment

F Z; Y Z; B C; HH M; J W; D C; C O; B F; P C; L S
Journal article: 2019

Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia

D H; F E; DM E; MB D; J B; D S; P W; D B; F S; E L; P H; M K; F DR; C C; ML B; L S; K B; P K; L R; A L
Article: ACTA PAEDIATRICA. 2019;108(9):1677-1685

High prevalence of pituitary hormone deficiency in both unilateral and bilateral optic nerve hypoplasia

Dahl S; Wiberg MK; Fahnehjelm KT; Savendahl L; Wickstrom R
Article: JAMA PEDIATRICS. 2019;173(9):860-865

Secular Trends in Pubertal Growth Acceleration in Swedish Boys Born From 1947 to 1996

Ohlsson C; Bygdell M; Celind J; Sonden A; Tidblad A; Savendahl L; Kindblom JM
Article: ENDOCRINE CONNECTIONS. 2019;8(9):1302-1309

Effects of the selective GPER1 agonist G1 on bone growth

Iravani M; Lagerquist MK; Karimian E; Chagin AS; OhIsson C; Savendahl L
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2019;73(8):730-736

Adult height is associated with risk of cancer and mortality in 5.5 million Swedish women and men

Benyi E; Linder M; Adami J; Kieler H; Palme M; Savendahl L
Article: JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY. 2019;60(7):803-812

Bidirectional relationship between eating disorders and autoimmune diseases

Hedman A; Breithaupt L; Hubel C; Thornton LM; Tillander A; Norring C; Birgegard A; Larsson H; Ludvigsson JF; Savendahl L; Almqvist C; Bulik CM
Article: NATURE REVIEWS NEPHROLOGY. 2019;15(7):435-455

Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia

Haffner D; Emma F; Eastwood DM; Duplan MB; Bacchetta J; Schnabel D; Wicart P; Bockenhauer D; Santos F; Levtchenko E; Harvengt P; Kirchhoff M; Di Rocco F; Chaussain C; Brandi ML; Savendahl L; Briot K; Kamenicky P; Rejnmark L; Linglart A
Journal article: JOURNAL OF THE ENDOCRINE SOCIETY. 2019;3(Supplement_1):sun-247

SUN-247 Once-Weekly Somapacitan in Childhood Growth Hormone Deficiency: Efficacy and Safety Results of a Randomized, Open-Label, Controlled Phase 2 Trial (REAL 3)

Savendahl L; Rasmussen MH; Horikawa R; Khadilkar V; Battelino T; Saenger P
Article: FASEB JOURNAL. 2019;33(4):4962-4974

Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment

Zaman F; Zhao Y; Celvin B; Mehta HH; Wan J; Chrysis D; Ohlsson C; Fadeel B; Cohen P; Savendahl L
Article: NATURE. 2019;567(7747):234-238

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

Newton PT; Li L; Zhou B; Schweingruber C; Hovorakova M; Xie M; Sun X; Sandhow L; Artemov AV; Ivashkin E; Suter S; Dyachuk V; El Shahawy M; Gritli-Linde A; Bouderlique T; Petersen J; Mollbrink A; Lundeberg J; Enikolopov G; Qian H; Fried K; Kasper M; Hedlund E; Adameyko I; Savendahl L; Chagin AS
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2019;104(3):658-664

Risk of Meningioma in European Patients Treated With Growth Hormone in Childhood: Results From the SAGhE Cohort

Swerdlow AJ; Cooke R; Beckers D; Butler G; Carel J-C; Cianfarani S; Clayton P; Coste J; Deodati A; Ecosse E; Hokken-Koelega ACS; Khan AJ; Kiess W; Kuehni CE; Flueck CE; Pfaffle R; Savendahl L; Sommer G; Thomas M; Tidblad A; Tollerfield S; Zandwijken GRJ
Article: BONE REPORTS. 2018;8:64-71

Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.

Newton PT; Xie M; Medvedeva EV; Sävendahl L; Chagin AS
Journal article: ENDOCRINE ABSTRACTS. 2018

Final results of NordiNet® international outcome study: key outcomes

Savendahl L; Puras G; Pedersen BT; Weber M
Journal article: CLINICAL ENDOCRINOLOGY. 2017;87(4):i

Cover Image, Volume 87, Issue 4

Battelino T; Rasmussen MH; De Schepper J; Zuckerman‐Levin N; Gucev Z; Sävendahl L; Group TNS
Article: CLINICAL ENDOCRINOLOGY. 2017;87(4):350-358

Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial

Battelino T; Rasmussen MH; De Schepper J; Zuckerman-Levin N; Gucev Z; Saevendahl L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2017;102(5):1661-1672

Cancer Risks in Patients Treated With Growth Hormone in Childhood: The SAGhE European Cohort Study

Swerdlow AJ; Cooke RG; Beckers DD; Borgstrom BE; Butler GB; Carel J-CC; Cianfarani SE; Clayton PG; Coste JA; Deodati AC; Ecosse EK; Gausche RB; Giacomozzi CE; Hokken-Koelega AC; Khan AJ; Kiess WB; Kuehni CE; Mullis P-EC; Pfaffle RL; Savendahl L; Sommer GL; Thomas MK; Tidblad AM; Tollerfield SL; Van Eycken LD; Zandwijken GR
Article: JOURNAL OF ENDOCRINOLOGY. 2017;232(3):403-410

Regulation of bone growth via ligand-specific activation of estrogen receptor alpha

Iravani M; Lagerquist M; Ohlsson C; Savendahl L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(5):2149-2159

Mortality Is Not Increased in Recombinant Human Growth Hormone-treated Patients When Adjusting for Birth Characteristics

Albertsson-Wikland K; Martensson A; Savendahl L; Niklasson A; Bang P; Dahlgren J; Gustafsson J; Kristrom B; Norgren S; Pehrsson N-G; Oden A
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2016;174(5):681-691

Is safety of childhood growth hormone therapy related to dose? Data from a large observational study

Savendahl L; Pournara E; Pedersen BT; Blankenstein O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(2):394-415

Global Consensus Recommendations on Prevention and Management of Nutritional Rickets

Munns CF; Shaw N; Kiely M; Specker BL; Thacher TD; Ozono K; Michigami T; Tiosano D; Mughal MZ; Makitie O; Ramos-Abad L; Ward L; DiMeglio LA; Atapattu N; Cassinelli H; Braegger C; Pettifor JM; Seth A; Idris HW; Bhatia V; Fu J; Goldberg G; Savendahl L; Khadgawat R; Pludowski P; Maddock J; Hypponen E; Oduwole A; Frew E; Aguiar M; Tulchinsky T; Butler G; Hogler W
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2016;174(2):P1-P9

GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults

Allen DB; Backeljauw P; Bidlingmaier M; Biller BMK; Boguszewski M; Burman P; Butler G; Chihara K; Christiansen J; Cianfarani S; Clayton P; Clemmons D; Cohen P; Darendeliler F; Deal C; Dunger D; Erfurth EM; Fuqua JS; Grimberg A; Haymond M; Higham C; Ho K; Hoffman AR; Hokken-Koelega A; Johannsson G; Juul A; Kopchick J; Lee P; Pollak M; Radovick S; Robison L; Rosenfeld R; Ross RJ; Savendahl L; Saenger P; Sorensen HT; Stochholm K; Strasburger C; Swerdlow A; Thorner M
Article: HORMONE RESEARCH IN PAEDIATRICS. 2016;85(5):347-352

The Evaluation and Management of Tall Stature

Hannema SE; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2016;85(2):83-106

Global Consensus Recommendations on Prevention and Management of Nutritional Rickets

Munns CF; Shaw N; Kiely M; Specker BL; Thacher TD; Ozono K; Michigami T; Tiosano D; Mughal MZ; Maekitie O; Ramos-Abad L; Ward L; DiMeglio LA; Atapattu N; Cassinelli H; Braegger C; Pettifor JM; Seth A; Idris HW; Bhatia V; Fu J; Goldberg G; Saevendahl L; Khadgawat R; Pludowski P; Maddock J; Hyppoenen E; Oduwole A; Frew E; Aguiar M; Tulchinsky T; Butler G; Hoegler W; Aguiar M; Atapattu N; Bhatia V; Braegger C; Butler G; Cassinelli H; DiMeglio LA; Frew E; Fu J; Goldberg G; Hypponen E; Idris HW; Khadgawat R; Kiely M; Maddock J; Makitie O; Michigami T; Mughal MZ; Munns CF; Oduwole A; Ozono K; Pettifor JM; Pludowski P; Ramos-Abad L; Savendahl L; Seth A; Shaw N; Specker BL; Thacher TD; Tiosano D; Tulchinsky T; Ward L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2015;16(4):8059-8069

Expression of the Aryl Hydrocarbon Receptor in Growth Plate Cartilage and the Impact of Its Local Modulation on Longitudinal Bone Growth

Cedervall T; Lind PM; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2015;84(3):172-183

Description of the SAGhE Cohort: A Large European Study of Mortality and Cancer Incidence Risks after Childhood Treatment with Recombinant Growth Hormone

Swerdlow AJ; Cooke R; Albertsson-Wikland K; Borgstrom B; Butler G; Cianfarani S; Clayton P; Coste J; Deodati A; Ecosse E; Gausche R; Giacomozzi C; Kiess W; Hokken-Koelega ACS; Kuehni CE; Landier F; Maes M; Mullis P-E; Pfaffle R; Savendahl L; Sommer G; Thomas M; Tollerfield S; Zandwijken GRJ; Carel J-C
Article: HORMONE RESEARCH IN PAEDIATRICS. 2015;83(5):361-364

Short Stature in KBG Syndrome: First Responses to Growth Hormone Treatment

Reynaert N; Ockeloen CW; Savendahl L; Beckers D; Devriendt K; Kleefstra T; Carels CEL; Grigelioniene G; Nordgren A; Francois I; de Zegher F; Casteels K
Article: ENDOCRINOLOGY. 2014;155(12):4798-4807

Combined Treatment With GH and IGF-I: Additive Effect on Cortical Bone Mass But Not on Linear Bone Growth in Female Rats

Sundstrom K; Cedervall T; Ohlsson C; Camacho-Hubner C; Savendahl L
Article: NATURE MEDICINE. 2014;20(11):1279-1288

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

Moverare-Skrtic S; Henning P; Liu X; Nagano K; Saito H; Borjesson AE; Sjogren K; Windahl SH; Farman H; Kindlund B; Engdahl C; Koskela A; Zhang F-P; Eriksson EE; Zaman F; Hammarstedt A; Isaksson H; Bally M; Kassem A; Lindholm C; Sandberg O; Aspenberg P; Savendahl L; Feng JQ; Tuckermann J; Tuukkanen J; Poutanen M; Baron R; Lerner UH; Gori F; Ohlsson C
Journal article: GROWTH HORMONE & IGF RESEARCH. 2014;24:s45

PO2-20: Safety evaluation of long-term recombinant growth hormone (rGH) treatment in paediatric patients: interim analysis of NordiNet® International Outcome Study (IOS)

Sävendahl L; Pournara E; Pedersen BT; Blankenstein O
Article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2014;25(10):2366-2375

Mutations in SLC34A3/NPT2c Are Associated with Kidney Stones and Nephrocalcinosis

Dasgupta D; Wee MJ; Reyes M; Li Y; Simm PJ; Sharma A; Schlingmann K-P; Janner M; Biggin A; Lazier J; Gessner M; Chrysis D; Tuchman S; Baluarte HJ; Levine MA; Tiosano D; Insogna K; Hanley DA; Carpenter TO; Ichikawa S; Hoppe B; Konrad M; Saevendahl L; Munns CF; Lee H; Jueppner H; Bergwitz C
Article: MOLECULAR CANCER. 2014;13:155

Bortezomib treatment causes long-term testicular dysfunction in young male mice

Hou M; Eriksson E; Svechnikov K; Jahnukainen K; Soder O; Meinhardt A; Savendahl L
Article: HUMAN GENETICS. 2014;133(5):587-597

Common DNA variants predict tall stature in Europeans

Liu F; Hendriks AEJ; Ralf A; Boot AM; Benyi E; Savendahl L; Oostra BA; van Duijn C; Hofman A; Rivadeneira F; Uitterlinden AG; Drop SLS; Kayser M
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2014;106(3):djt459

Protective Role of Humanin on Bortezomib-Induced Bone Growth Impairment in Anticancer Treatment

Eriksson E; Wickstrom M; Perup LS; Johnsen JI; Eksborg S; Kogner P; Savendahl L
Article: TOXICOLOGY LETTERS. 2014;224(2):196-200

Dexamethasone differentially regulates Bcl-2 family proteins in human proliferative chondrocytes: Role of pro-apoptotic Bid

Zaman F; Chrysis D; Huntjens K; Chagin A; Takigawa M; Fadeel B; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2014;82(2):89-96

Risks of Malignant and Non-Malignant Tumours in Tall Women Treated with High-Dose Oestrogen during Adolescence

Benyi E; Kieler H; Linder M; Ritzen M; Carlstedt-Duke J; Tuvemo T; Westphal O; Savendahl L
Article: EMBO JOURNAL. 2013;32(2):219-230

Identification of a clonally expanding haematopoietic compartment in bone marrow

Wang L; Benedito R; Bixel MG; Zeuschner D; Stehling M; Savendahl L; Haigh JJ; Snippert H; Clevers H; Breier G; Kiefer F; Adams RH
Article: CLINICAL EPIDEMIOLOGY. 2013;5:119-127

The NordiNet® International Outcome Study and NovoNet® ANSWER Program®: rationale, design, and methodology of two international pharmacoepidemiological registry-based studies monitoring long-term clinical and safety outcomes of growth hormone therapy (Norditropin®).

Höybye C; Sävendahl L; Christesen HT; Lee P; Pedersen BT; Schlumpf M; Germak J; Ross J
Article: PLOS ONE. 2013;8(6):e67859

Resveratrol Treatment Delays Growth Plate Fusion and Improves Bone Growth in Female Rabbits

Karimian E; Tamm C; Chagin AS; Samuelsson K; Kjartansdottir KR; Ohlsson C; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2013;80(1):6-10

Vitamin D Levels in Children Born to Vitamin D-Deficient Mothers

Bergstrom I; Blanck A; Savendahl L
Article: SCIENCE SIGNALING. 2012;5(247):pt9

ENDOCRINOLOGY The Effect of Acute and Chronic Stress on Growth

Savendahl L
Journal article: GROWTH HORMONE & IGF RESEARCH. 2012;22:s30-s31

OR11-6 Long-term mortality in patients with isolated GHD, ISS, and SGA treated with recombinant GH during childhood in Sweden: Application of a mortality model developed from the general population

Wikland KA; Sävendahl L; Märtensson A; Borgström B; Niklasson A; Pehrson NG; Bang P; Dahlgren J; Gustafson J; Hagenäs L; Kriström B; Norgren S; Odén A
Article: INTERNATIONAL JOURNAL OF PEDIATRIC ENDOCRINOLOGY. 2012;2012(1):22

Comparison of response to 2-years' growth hormone treatment in children with isolated growth hormone deficiency, born small for gestational age, idiopathic short stature, or multiple pituitary hormone deficiency: combined results from two large observational studies.

Lee PA; Sävendahl L; Oliver I; Tauber M; Blankenstein O; Ross J; Snajderova M; Rakov V; Pedersen BT; Christesen HT
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;302(11):E1381-E1389

The role of estrogen receptor-α and its activation function-1 for growth plate closure in female mice

Boerjesson AE; Windahl SH; Karimian E; Eriksson EE; Lagerquist MK; Engdahl C; Antal MC; Krust A; Chambon P; Saevendahl L; Ohlsson C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2012;97(2):E213-E217

Long-Term Mortality and Causes of Death in Isolated GHD, ISS, and SGA Patients Treated with Recombinant Growth Hormone during Childhood in Belgium, The Netherlands, and Sweden: Preliminary Report of 3 Countries Participating in the EU SAGhE Study

Savendahl L; Maes M; Albertsson-Wikland K; Borgstrom B; Carel J-C; Henrard S; Speybroeck N; Thomas M; Zandwijken G; Hokken-Koelega A
Article: PLOS ONE. 2012;7(3):e33168

Ablation of the Pro-Apoptotic Protein Bax Protects Mice from Glucocorticoid-Induced Bone Growth Impairment

Zaman F; Chrysis D; Huntjens K; Fadeel B; Savendahl L
Article: PLOS ONE. 2012;7(11):e50523

Bortezomib Is Cytotoxic to the Human Growth Plate and Permanently Impairs Bone Growth in Young Mice

Eriksson E; Zaman F; Chrysis D; Wehtje H; Heino TJ; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2012;77(3):188-194

Gender Influences Short-Term Growth Hormone Treatment Response in Children

Savendahl L; Blankenstein O; Oliver I; Christesen HT; Lee P; Pedersen BT; Rakov V; Ross J
Article: HORMONE RESEARCH IN PAEDIATRICS. 2012;77(3):180-187

Pro-Inflammatory Cytokines Produced by Growth Plate Chondrocytes May Act Locally to Modulate Longitudinal Bone Growth

Fernandez-Vojvodich P; Palmblad K; Karimian E; Andersson U; Savendahl L
Journal article: CURRENT PEDIATRIC REVIEWS. 2011;7(4):301-309

Double-Edged Sword of Novel Anti-Cancer Treatment: Proteasome Inhibition in the Growth Plate Causes Impairment of Longitudinal Bone Growth

Zaman F; Fadeel B; Savendahl L
Article: HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM. 2011;10(1):46-56

Insulin-like growth factor-1 restores dexamethasone-induced heart growth arrest in rats: the role of the ubiquitin pathway

Chrysis D; Chagin AS; Savendahl L
Article: FRONTIERS IN ENDOCRINOLOGY. 2011;2:113

Genetic regulation of the growth plate.

Karimian E; Chagin AS; Sävendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2011;75(5):354-361

Intravenous Pamidronate Treatment Improves Growth in Prepubertal Osteogenesis Imperfecta Patients

Heino TJ; Astrom E; Laurencikas E; Savendahl L; Soderhall S
Article: HORMONE RESEARCH IN PAEDIATRICS. 2011;76(4):278-285

The Biologics Anakinra and Etanercept Prevent Cytokine-Induced Growth Retardation in Cultured Fetal Rat Metatarsal Bones

Fernandez-Vojvodich P; Karimian E; Savendahl L
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2010;25(12):2414-2424

The Role of Estrogen Receptor α in Growth Plate Cartilage for Longitudinal Bone Growth

Borjesson AE; Lagerquist MK; Liu C; Shao R; Windahl SH; Karlsson C; Sjogren K; Moverare-Skrtic S; Antal MC; Krust A; Mohan S; Chambon P; Savendahl L; Ohlsson C
Article: ACADEMIC RADIOLOGY. 2010;17(11):1425-1432

Validation and Reference Values of Automated Bone Age Determination for Four Ethnicities

Thodberg HH; Savendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2010;205(1):61-68

Expression of vascular endothelial growth factor in the growth plate is stimulated by estradiol and increases during pubertal development

Emons J; Chagin AS; Malmlof T; Lekman M; Tivesten A; Ohlsson C; Wit JM; Karperien M; Savendahl L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(5):3462-3469

Proinsulin C-peptide Regulates Ribosomal RNA Expression

Lindahl E; Nyman U; Zaman F; Palmberg C; Cascante A; Shafqat J; Takigawa M; Savendahl L; Jorvall H; Joseph B
Article: INTERNATIONAL JOURNAL OF PEDIATRIC ENDOCRINOLOGY. 2010;2010:740629-7

Efficacy and Safety of Percutaneous Epiphysiodesis Operation around the Knee to Reduce Adult Height in Extremely Tall Adolescent Girls and Boys.

Benyi E; Berner M; Bjernekull I; Boman A; Chrysis D; Nilsson O; Waehre A; Wehtje H; Sävendahl L
Journal article: INTERNATIONAL JOURNAL OF PEDIATRIC ENDOCRINOLOGY. 2010;2010(1):740629

Efficacy and Safety of Percutaneous Epiphysiodesis Operation around the Knee to Reduce Adult Height in Extremely Tall Adolescent Girls and Boys

Benyi E; Berner M; Bjernekull I; Boman A; Chrysis D; Nilsson O; Waehre A; Wehtje H; Sävendahl L
Journal article: GROWTH HORMONE & IGF RESEARCH. 2010;20:s51

P31 Earlier start of puberty in GH treated children born SGA than in GH treated for GHD. Data from the NordiNet® IOS

Rakov V; Blankenstein O; Oliver I; Pedersen BT; Sävendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2010;204(1):21-29

Catch-up growth after dexamethasone withdrawal occurs in cultured postnatal rat metatarsal bones

Chagin AS; Karimian E; Sundstrom K; Eriksson E; Savendahl L
Article: PEDIATRIC RESEARCH. 2009;66(6):654-659

Epiphyseal Fusion in the Human Growth Plate Does not Involve Classical Apoptosis

Emons J; Chagin AS; Hultenby K; Zhivotovsky B; Wit JM; Karperien M; Savendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:42-47

Promoting Growth in Chronic Inflammatory Disease: Lessons from Studies of the Growth Plate

Ahmed SF; Savendahl L
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2009;296(3):E490-E496

The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice

Windahl SH; Andersson N; Chagin AS; Martensson UEA; Carlsten H; Olde B; Swanson C; Moverare-Skrtic S; Savendahl L; Lagerquist MK; Leeb-Lundberg LMF; Ohlsson C
Article: HORMONE RESEARCH IN PAEDIATRICS. 2009;71(4):219-227

Androgen Receptor Modulation Does Not Affect Longitudinal Growth of Cultured Fetal Rat Metatarsal Bones

Chagin AS; Vannesjo J; Savendahl L
Journal article: GROWTH HORMONE & IGF RESEARCH. 2008;18:s40

P-44 Gender related IGF-I changes after two years of growth hormone (GH) treatment in GH deficient (GHD) children and adults. Data from the NordiNet® International Outcome Study (IOS)

Sävendahl L; Pedersen BT; Rakov V; Christiansen JS
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2008;23(8):1267-1277

Tamoxifen impairs both longitudinal and cortical bone growth in young male rats

Karimian E; Chagin AS; Gjerde J; Heino T; Lien EA; Ohllsson C; Savendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2008;197(2):R1-R6

The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone

Heino TJ; Chagin AS; Savendahl L
Article: BONE. 2008;42(4):702-709

Effects of alendronate and pamidronate on cultured rat metatarsal bones:: Failure to prevent dexamethasone-induced growth retardation

Heino TJ; Chagin AS; Takigawa M; Savendahl L
Article: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM. 2008;21(3):287-294

The 7th ESPE Growth Plate Working Group symposium--EUROGROP, June 27th 2007, Helsinki, Finland.

Miclea RL; Phillip M; Sävendahl L; Wit JM
Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2008;8(2):458-462

Intramuscular autotransplantation of pancreatic islets in a 7-year-old child:: A 2-year follow-up

Rafael E; Tibell A; Ryden M; Lundgren T; Savendhal L; Borgstrom B; Arnelo U; Isaksson B; Nilsson B; Korsgren O; Permert J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2007;92(12):4873-4877

GPR30 estrogen receptor expression in the growth plate declines as puberty progresses

Chagin AS; Savendahl L
Article: JOURNAL OF RHEUMATOLOGY. 2007;34(12):2481-2485

Etanercept treatment improves longitudinal growth in prepubertal children with juvenile idiopathic arthritis

Vojvodich PF; Hansen JB; Andersson U; Savendahl L; Hagelberg S
Article: CANCER RESEARCH. 2007;67(20):10078-10086

Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice

Zaman F; Menendez-Benito V; Eriksson E; Chagin AS; Takigawa M; Fadeel B; Dantuma NP; Chrysis D; Saevendahl L
Article: BONE. 2007;40(5):1415-1424

Tamoxifen induces permanent growth arrest through selective induction of apoptosis in growth plate chondrocytes in cultured rat metatarsal bones

Chagin AS; Karimian E; Zaman F; Takigawa M; Chrysis D; Savendahl L
Journal article: GROWTH HORMONE & IGF RESEARCH. 2006;16:s40

P-93 NordiNet®: FROM PATIENT MANAGEMENT TO OUTCOME RESEARCH TOOL

Rakov V; Faerch J; Christiansen JS; Savendahl L
Journal article: GROWTH HORMONE & IGF RESEARCH. 2006;16:s20

OR10-3 BASELINE CHARACTERISTICS AND TREATMENT RESPONSE TO GH IN GH-DEFICIENT CHILDREN REPORTED TO THE NordiNet® OUTCOME DATABASE

Rakov V; Savendahl L; Faerch J
Article: ACTA RADIOLOGICA. 2006;47(5):518-524

Metacarpophalangeal pattern profile analysis:: Useful diagnostic tool for differentiating between dyschondrosteosis, Turner syndrome, and hypochondroplasia

Laurencikas E; Sävendahl L; Jorulf H
Article: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM. 2006;19(2):183-190

The Fifth European Growth Plate Working Group Symposium. 21st September 2005, Lyon, France.

Kalirai H; Phillip M; Savendahl L; Wit J-M
Article: JOURNAL OF ENDOCRINOLOGY. 2006;188(2):193-203

Locally produced estrogen promotes fetal rat metatarsal bone growth;: an effect mediated through increased chondrocyte proliferation and decreased apoptosis

Chagin AS; Chrysis D; Takigawa M; Ritzen EM; Sävendahl L
Article: ACTA PAEDIATRICA. 2005;94(8):1096-1101

Glucocorticoid eye drops inhibit growth in the newborn rabbit

Kugelberg M; Shafiei K; Ohlsson C; Sävendahl L; Zetterström C
Article: ACTA RADIOLOGICA. 2005;46(4):424-430

Metacarpophalangeal pattern profile analysis as a tool for early diagnosis of Turner syndrome

Laurencikas E; Söderman E; Davenport M; Jorulf H; Sävendahl L
Article: ENDOCRINOLOGY. 2005;146(3):1391-1397

Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3′-kinase signaling pathway

Chrysis D; Zaman F; Chagin AS; Takigawa M; Sävendahl L
Article: HORMONE RESEARCH IN PAEDIATRICS. 2005;63(4):165-170

Reduced bone mineral density and radial bone growth in young rabbits treated with dexamethasone eye drops

Kugelberg M; Ohlsson C; Sävendahl L
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2004;19(11):1833-1839

Additive protective effects of estrogen and androgen treatment on trabecular bone in ovariectomized rats

Tivesten A; Movérare-Skrtic S; Chagin A; Venken K; Salmon P; Vanderschueren D; Sävendahl L; Holmäng A; Ohlsson C
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2004;19(11):1805-1812

Interleukin-1β and TNF-α act in synergy to inhibit longitudinal growth in fetal rat metatarsal bones

Mårtensson K; Chrysis D; Sävendahl L
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2004;19(1):72-77

Estrogen receptor-β inhibits skeletal growth and has the capacity to mediate growth plate fusion in female mice

Chagin AS; Lindberg MK; Andersson N; Moverare S; Gustafsson J; Sävendahl L; Ohlsson C
Article: JOURNAL OF ENDOCRINOLOGY. 2003;177(2):319-326

Localization of estrogen receptors-α and -β and androgen receptor in the human growth plate at different pubertal stages

Nilsson O; Chrysis D; Pajulo I; Boman A; Holst M; Rubinstein J; Ritzén EM; Sävendahl L
Article: ENDOCRINOLOGY. 2003;144(4):1481-1485

Raloxifene acts as an estrogen agonist on the rabbit growth plate

Nilsson O; Falk J; Ritzén EM; Baron J; Sävendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2003;176(3):331-337

Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes

Chrysis D; Ritzen EM; Sävendahl L
Article: ENDOCRINE. 2002;18(3):271-278

Apoptosis is developmentally regulated in rat growth plate

Chrysis D; Nilsson O; Ritzen EM; Sävendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2002;174(2):r1-r6

Expression and localization of Indian hedgehog (Ihh) and parathyroid hormone related protein (PTHrP) in the human growth plate during pubertal development

Kindblom JM; Nilsson O; Hurme T; Ohlsson C; Sävendahl L
Article: JOURNAL OF ENDOCRINOLOGY. 2002;173(3):407-414

Estrogen receptor-α and -β are expressed throughout postnatal development in the rat and rabbit growth plate

Nilsson O; Abad V; Chrysis D; Ritzén EM; Sävendahl L; Baron J
Article: HORMONE RESEARCH IN PAEDIATRICS. 2002;57(5-6):157-164

Growth failure in early life:: An important manifestation of Turner syndrome

Davenport ML; Punyasavatsut N; Stewart PW; Gunther DF; Sävendahl L; Sybert VP
Journal article: JOURNAL OF PEDIATRICS. 2002;140(1):140

Screening for Turner's syndrome by chromosome analysis of all girls with short stature

Partsch CJ; Raffenberg U; Sippell WG
Article: JOURNAL OF NUTRITION. 2001;131(11):2963-2966

Body fat content can be predicted in vivo in mice using a modified dual-energy X-ray absorptiometry technique

Sjögren K; Hellberg N; Bohlooly-Y M; Savendahl L; Johansson MS; Berglindh T; Bosaeus I; Ohlsson C
Article: JOURNAL OF PEDIATRICS. 2000;137(4):455-459

Delayed diagnoses of Turner's syndrome:: Proposed guidelines for change

Sävendahl L; Davenport ML
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;265(2):569-571

Disproportional body growth in female estrogen receptor-α-inactivated mice

Vidal O; Lindberg M; Sävendahl L; Lubahn DB; Ritzen EM; Gustafsson J; Ohlsson C
Article: JOURNAL OF NUTRITION. 1999;129(11):2005-2008

Fasting increases serum total cholesterol, LDL cholesterol and apolipoprotein B in healthy, nonobese humans

Sävendahl L; Underwood LE
Journal article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1999;84(1):370-373

Demonstration of Estrogen Receptor- Immunoreactivity in Human Growth Plate Cartilage

Nilsson LO
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1999;84(1):370-373

Demonstration of estrogen receptor-β immunoreactivity in human growth plate cartilage

Nilsson LO; Boman A; Sävendahl L; Grigelioniene G; Ohlsson C; Ritzen EM; Wroblewski J
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 1997;66(3):622-625

Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction

Savendahl L; Mar MH; Underwood LE; Zeisel SH
Journal article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1997;82(4):1177-1180

Decreased Interleukin-2 Production from Cultured Peripheral Blood Mononuclear Cells in Human Acute Starvation

Savendahl L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1997;82(4):1177-1180

Decreased interleukin-2 production from cultured peripheral blood mononuclear cells in human acute starvation

Savendahl L; Underwood LE
Article: ENDOCRINOLOGY. 1997;138(2):734-740

Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid

Savendahl L; Underwood LE; Haldeman KM; Ulshen MH; Lund PK
Article: ENDOCRINOLOGY. 1996;137(10):4174-4180

Enrichment of type I and type II rat somatotrophs: Characterization of growth hormone secretion in vitro

Lindstrom P; Savendahl L
Article: CYTOMETRY. 1995;20(1):7-13

CELL-VOLUME AND SHAPE OSCILLATIONS IN RAT TYPE-II SOMATOTROPHS AT HYPOTONIC CONDITIONS

ENGSTROM KG; SAVENDAHL L
Article: THROMBOSIS AND HAEMOSTASIS. 1995;73(4):626-629

GROWTH-HORMONE DEFICIENCY IMPAIRS BLOOD-CLOTTING AND REDUCES FACTOR-VII COAGULANT ACTIVITY IN RAT

SAVENDAHL LSG; GRANKVIST K; ENGSTROM KG
Journal article: HORMONE RESEARCH IN PAEDIATRICS. 1994;41(1):21-26

LACK OF EVIDENCE FOR ACUTE EFFECTS OF GROWTH HORMONE-RELEASING HORMONE ON SERUM-INSULIN AND GLUCOSE-LEVELS IN NORMAL AND HYPOPHYSECTOMIZED RATS

ENGSTROM G; LINDSTROM P; SAVENDAHL L
Journal article: ACTA ENDOCRINOLOGICA. 1993;129(3):268-272

EFFECTS OF GALANIN ON GROWTH-HORMONE RELEASE IN ISOLATED CULTURED RAT SOMATOTROPHS

LINDSTROM P; SAVENDAHL L
Journal article: PEDIATRIC RESEARCH. 1993;33(Suppl 5):s63

LOW PROCONVERTIN (FACTOR VII) AND IMPAIRED BLOOD CLOTTING DUE TO GROWTH HORMONE DEFICIENCY IN THE RAT

Sävendahl LS; Engström KG; Grankvist K
Visa fler

Alla övriga publikationer

Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2023;62:pa5030

Comorbidity of allergic diseases and type 1 diabetes - using genetically informative methods

Smew AI; Gong T; Kuja-Halkola R; Savendahl L; Lichtenstein P; Brew BK; Almqvist C
Preprint: MEDRXIV. 2023

Standardization of weightage assigned to different segments of the hand X-ray for assessment of bone age by the Greulich Pyle method

Oza C; Khadilkar AV; Goel P; Aeppli T; Mondkar S; Shah N; Lohiya N; Prasad HK; Patil P; Kajale N; Khadilkar V; Sävendahl L
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2023;38:132

Growth Hormone targets epiphyseal stem cells to direct skeletal growth

Zhou B; Chu T; Artemov A; Kryukov E; Newton P; Bendre A; Savendahl L; Ohlsson C; Nilsson O; Adameyko I; Chagin A
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2023;96(SUPPL 3):200-201

Development of A Minimum Data Set for A Growth Hormone Module For Pediatric Growth Hormone Deficiency In The Global Registry For Novel Therapies In Rare Bone & Endocrine Conditions - The GloBE-Reg GH Study

Miller BS; Chen SC; Charmandari E; Choi JH; Dou X; Gong C; Hamza R; Harvey J; Hoffman AR; Horikawa R; Johannsson G; Jorge A; Miller RS; Roehrich S; Savendahl L; Tseretopoulou X; Vitali D; Wajnrajch MP; Ahmed SF
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2023;96(SUPPL 2):101

Development of a minimum data set for the monitoring of recombinant human growth hormone (rhGH) therapy in children with growth hormone deficiency (GHD)- a globe-reg initiative

Chen SC; Charmandari E; Choi J-H; Dou X; Gong C; Hamza R; Harvey J; Hoffman AR; Horikawa R; Johannson G; Jorje A; Miller B; Savendahl L; Tseretopoulou X; Vitali D; Ahmed SF
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2023;96:12

Safety of GH treatment in cancer survivors

Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2023;96:323

A systematic review of core outcomes reported in clinical trials of growth hormone therapy in children with growth hormone deficiency

Tseretopoulou X; Lucas-Herald A; Chen J; Bachega T; Charmandari E; Choi J-H; Dou X; Gong C; Hamza R; Harvey J; Hoffman AR; Horikawa R; Johannsson G; Jorge A; Miller BS; Roehrich S; Savendahl L; Vitali D; Wajnrajch M; Chen SC; Ahmed SF
Book chapter: OXFORD TEXTBOOK OF ENDOCRINOLOGY AND DIABETES 3E. 2022;p. 1148-1158

Tall Stature

Sävendahl L; Benyi E
Letter: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2022;107(2):e888-e889

Letter to the Editor From Savendahl et al.: "Weekly Lonapegsomatropin in Treatment-Naive Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial"

Savendahl L; Battelino T; Brod M; Rasmussen MH; Kildemoes RJ; Saenger P
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2022;37:179-180

Regulation of the Epiphyseal Stem Cells in the Growth Plate by Growth Hormone

Zhou B; Bendre A; Savendahl L; Nilsson O; Chagin A
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2022;95(SUPPL 2):272-273

A Long-Acting Growth Hormone Module For Paediatric Growth Hormone Deficiency In The Global Registry For Novel Therapies In Rare Bone & Endocrine Conditions - The GloBE-Reg LAGH Study

Miller B; Savendahl L; Hickman K; Smythe C; Chen C; Choi J-H; Dou X; Gong C; Hamza R; Horikawa R; Jorge A; Ahmed SF
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2022;95(SUPPL 2):145

Effects of pharmacological inhibition of BCL-2 on linear bone growth

Velentza L; Wickstrom M; Kogner P; Zaman F; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2022;95(SUPPL 2):85

Efficacy, Observer-Reported Outcomes, and Safety of Once-Weekly Somapacitan in Children with Growth Hormone Deficiency (GHD): 4-Year Results from the REAL 3 Trial

Savendahl L; Battelino T; Rasmussen MH; Brod M; Lee KW; Saenger P; Horikawa R
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2022;95(SUPPL 2):86

Efficacy and safety of bilateral epiphysiodesis in extremely tall adolescents

Aeppli T; Benyi E; Wehtje H; Savendahl L
Review: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. 2021;168:103492

Bone health in glucocorticoid-treated childhood acute lymphoblastic leukemia

Velentza L; Zaman F; Savendahl L
Letter: JAMA PEDIATRICS. 2021;175(6):646-647

untitled reply

Tidblad A; Savendahl L
Other: BONE REPORTS. 2021;14:101089

Primary chronic osteomyelitis of the jaw: Rapid improvement after hormonal suppression in a girl with precocious puberty

Robertsson C; Savendahl L; Cardemil C
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2021;94(SUPPL 1):57-58

Once-weekly somapacitan versus daily growth hormone in growth hormone deficiency: 3-year efficacy and safety results from REAL 3, a randomised controlled phase 2 trial

Savendahl L; Battelino T; Rasmussen MH; Saenger P; Horikawa R
Corrigendum: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(12):dgaa614-e4982

Corrigendum to: "Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial".
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:1214

Familial co-aggregation of asthma and type 1 diabetes mellitus in children- a Swedish population-based cohort study

Smew A; Lundholm C; Savendahl L; Lichtenstein P; Almqvist C
Corrigendum: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(6):dgaa139-e2319

Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet® IOS and ANSWER Program (vol 104, pg 4730, 2019)

Savendahl L; Polak M; Backeljauw P; Blair J; Miller B; Rohrer T; Pietropoli A; Ostrow V; Ross J
Preprint: SSRN ELECTRONIC JOURNAL. 2020

Childhood Growth Hormone Treatment and Long-Term Cardiovascular Morbidity

Tidblad A; Bottai M; Kieler H; Albertsson-Wikland K; Sävendahl L
Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2020;38(15)

Can body size explain the excess cancer risk in men?

Radkiewicz C; Sjolander A; Benyi E; Lambe M; Dickman P; Savendahl L; Edgren G
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2019;91:64-65

Once-weekly somapacitan vs daily growth hormone (Norditropin®) in childhood growth hormone deficiency: One-year results from a randomised phase 2 trial

Savendahl L; Battelino T; Horikawa R; Juul RV; Rasmussen MH; Saenger P
Book chapter: ENCYCLOPEDIA OF ENDOCRINE DISEASES. 2019;p. 94-101

Tall Stature

Hannema SE; Sävendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2018;90:44

Final Results of NordiNet® International Outcome Study: Key Outcomes in Pediatric Patients

Polak M; Blair J; Rohrer T; Pietropoli A; Berger M; Pedersen B; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2018;90:32

Radial ESWT Stimulates Longitudinal Bone Growth in Cultured Rat Fetal Metatarsal Bones

Ramesh S; Zaman F; Madhuri V; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2018;90:440

Final Results of Nordinet® International Outcome Study: Key Outcomes in Paediatric Patients

Polak M; Blair J; Rohrer TR; Pietropoli A; Pedersen BT; Savendahl L
Review: JOURNAL OF ENDOCRINOLOGY. 2018;236(1):R69-R91

Animal models to explore the effects of glucocorticoids on skeletal growth and structure

Wood CL; Soucek O; Wang SC; Zaman F; Farquharson C; Savendahl L; Ahmed SF
Corrigendum: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(10):4382

Proinsulin C-peptide regulates ribosomal RNA expression (vol 292, pg 3467, 2017)

Lindahl E; Nyman U; Zaman F; Palmberg C; Cascante A; Shafqat J; Takigawa M; Saevendahl L; Joernvall H; Joseph B
Corrigendum: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2017;176(3):X1-XI

Is safety of childhood growth hormone therapy related to dose? Data from a large observational study (vol 174, pg 681, 2016)

Savendahl L; Pournara E; Pedersen BT; Blankenstein O
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2017;88:483

SAFETY OUTCOMES IN PEDIATRIC PATIENTS WITH TURNER SYNDROME TREATED WITH GROWTH HORMONE

Blankenstein O; Backeljauw P; Chudecka AI; Roehrich S; Pedersen BT; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2017;88:4

MECHANISMS OF FIBROBLAST GROWTH FACTOR 21 (FGF21) MEDIATED GROWTH HORMONE RESISTANCE IN HUMAN GROWTH PLATE IN CHRONIC CHILDHOOD CONDITIONS

Mistry JN; Ruiz-Babot G; Zaman F; Savendahl L; Guasti L; Dunkel L
Review: HORMONE RESEARCH IN PAEDIATRICS. 2017;88(1):6-14

The Physiology of Childhood Growth: Hormonal Regulation

Benyi E; Savendahl L
Review: ENDOCRINE CONNECTIONS. 2016;5(6):R44-R54

Bridging the gap: metabolic and endocrine care of patients during transition

Hokken-Koelega A; van der Lely A-J; Hauffa B; Haeusler G; Johannsson G; Maghnie M; Argente J; DeSchepper J; Gleeson H; Gregory JW; Hoybye C; Kelestimur F; Luger A; Mueller HL; Neggers S; Popovic-Brkic V; Porcu E; Savendahl L; Shalet S; Spiliotis B; Tauber M
Letter: LANCET ONCOLOGY. 2016;17(8):e319-e320

Venetoclax in cancer therapy and potential effects on bone

Zaman F; Kogner P; Savendahl L
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2016;374(22):2185

New Agents to Treat Chronic Lymphocytic Leukemia

Zaman F; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2016;86:49

Birth Characteristics Explain One Third of Expected Deaths in rhGH-treated Patients Diagnosed with IGHD, ISS & SGA

Albertsson-Wikland K; Martensson A; Savendahl L; Niklasson A; Bang P; Dahlgren J; Gustafsson J; Kristrom B; Norgren S; Pehrsson N-G; Oden A
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2016;86:114-115

Contribution of GHR and IGFALS Mutations to Growth Hormone Resistance - Identification of New Variants and Impact on the Inheritance Pattern

Legendre M; Dastot F; Collot N; Duquesnoy P; Cohen E; Sobrier M-L; Adiceam P; Anderson D; Baron S; Cabrol S; Callewaert B; Cartigny M; Craen M; Crock P; Ladjouze A; Lazea C; Polak M; Savendahl L; Touzani A; Amselem S
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2016;86:165

Effects of Selective GPER-1 Agonist G1 on Bone Growth

Iravani M; Karimian E; Chagin A; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2016;86:382-383

An Analysis of the Safety of Childhood Growth Hormone (GH) Therapy: Data from the NordiNet® International Outcome Study (IOS)

Savendahl L; Rohrer TR; Pedersen BT; Blankenstein O
Review: NATURE REVIEWS ENDOCRINOLOGY. 2015;11(12):735-746

Short and tall stature: a new paradigm emerges

Baron J; Saevendahl L; De Luca F; Dauber A; Phillip M; Wit JM; Nilsson O
Review: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2014;53(1):T35-T44

RECENT RESEARCH ON THE GROWTH PLATE Impact of inflammatory cytokines on longitudinal bone growth

Sederquist B; Fernandez-Vojvodich P; Zaman F; Savendahl L
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2014;29:S351

Targeted Deletion of Atg5 or Atg7 in Chondrocytes Impairs Cell Viability and Bone Growth.

Vuppalapati K; Bouderlique T; Kaminskyy V; Newton P; Savendahl L; Zhivotovsky B; Chagin A
Editorial comment: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(10):e24-E25

Interleukin-6 acts locally on the growth plate to impair bone growth

Fernandez-Vojvodich P; Zaman F; Savendahl L
Letter: EUROPEAN JOURNAL OF HAEMATOLOGY. 2013;90(6):533-534

Bortezomib and bone health in adults: can we extend these findings to children?

Eriksson E; Savendahl L; Zaman F
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2013;28

WNT16 is a Novel Osteoblast-Derived Paracrine Regulator of Osteoclastogenesis, Cortical Bone Mass and Fracture Susceptibility

Skrtic SM; Henning P; Borjesson A; Sjogren K; Windahl S; Isaksson H; Eriksson E; Zaman F; Savendahl L; Lerner U; Ohlsson C
Conference publication: BONE. 2012;50:S48

Inhibition of autophagy promotes chondrocyte differentiation and stimulates longitudinal bone growth

Vuppalapati KK; Kaminsky V; Savendahl L; Zhivotovsky B; Chagin AS
Meeting abstract: BONE. 2012;50:S59

The role of estrogen receptor-alpha and its activation function 1 (af-1) for growth plate closure in female mice

Borjesson AE; Windahl SH; Karimian E; Eriksson EE; Lagerquist MK; Engdahl C; Antal MC; Krust A; Chambon P; Savendahl L; Ohlsson C
Conference publication: OSTEOPOROSIS INTERNATIONAL. 2012;23:S359

VITAMIN D LEVELS IN CHILDREN OF VITAMIN D DEFICIENT IMMIGRANT MOTHERS

Bergstrom I; Blanck A; Savendahl L
Review: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2011;9(2):554-565

Growth hormone and treatment outcomes: expert review of current clinical practice.

Cassorla F; Cianfarani S; Haverkamp F; Labarta JI; Loche S; Luo X; Maghnie M; Mericq V; Muzsnai A; Norgren S; Ojaniemi M; Pribilincova Z; Quinteiro S; Savendahl L; Spinola e Castro A; Gasteyger C
Book: ENDOCRINE DEVELOPMENT. 2011

Cartilage and Bone Development and Its Disorders
Book chapter: CARTILAGE AND BONE DEVELOPMENT AND ITS DISORDERS: ENDOCRINE DEVELOPMENT. 2011;p. I-XI

Title Page / Table of Contents / Acknowledgments / Preface / List of Abbreviations
Editorial comment: ACTA PAEDIATRICA. 2011;100(4):484-485

Vitamin D deficiency during pregnancy-potential threat to the child

Savendahl L
Review: ENDOCRINE DEVELOPMENT. 2011;21:42-51

Estrogen signaling in growth plate cartilage.

Karimian E; Sävendahl L
Review: HORMONE RESEARCH IN PAEDIATRICS. 2011;76(1):1-9

The Use of Bone Age in Clinical Practice - Part 1

Martin DD; Wit JM; Hochberg Z; Savendahl L; van Rijn RR; Fricke O; Cameron N; Caliebe J; Hertel T; Kiepe D; Albertsson-Wikland K; Thodberg HH; Binder G; Ranke MB
Review: HORMONE RESEARCH IN PAEDIATRICS. 2011;75(6):383-391

Mechanisms of Growth Plate Maturation and Epiphyseal Fusion

Emons J; Chagin AS; Savendahl L; Karperien M; Wit JM
Other: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2010;8(2):123-125

Highlights from the Second European Workshop on Growth Plate Research 2010.

Späth S-S; Sävendahl L; Camacho-Hübner C; Nilsson O
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2010: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2010;p. 65-81

Bone, Growth Plate and Mineral Metabolism

Heino T; Tiosano D; Gawlik A; Sävendahl L
Conference publication: ENDOCRINE REVIEWS. 2010;31(3)

Age and Severity of Growth Retardation at Treatment Start, but Not Degree of Prematurity or IUGR Are Related to One and Two Year GH Treatment Response in Short Children Born SGA: Data from the Nordinet® IOS and ANSWER® Program.

Lee PA; Blankenstein O; Pienkowski C; Oliver I; Snajderova M; Rakov V; Pedersen BT; Germak J; Savendahl L
Review: HORMONE RESEARCH IN PAEDIATRICS. 2010;73(3):161-165

Hormones and Genes of Importance in Bone Physiology and Their Influence on Bone Mineralization and Growth in Turner Syndrome

Andrade AC; Baron J; Manolagas SC; Shaw NJ; Rappold GA; Donaldson MDC; Gault EJ; Saevendahl L
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2009: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2009;p. 61-78

Growth Plate, Bone and Calcium

Heino T; Tiosano D; Sävendahl L
Published conference paper: HORMONE RESEARCH IN PAEDIATRICS. 2009;71:41-47

Genes of Importance in the Hormonal Regulation of Growth Plate Cartilage

Chagin AS; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:223

Improved growth during the first year of monthly intravenous pamidronate therapy in prepubertal patients with osteogenesis imperfecta

Heino TJ; Astrom E; Savendahl L; Soderhall S
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:275-276

Genome wide screening and morphological analysis of the human growth plate during pubertal development

Emons JAM; Leijten J; van Zwet E; Goeman J; Decker E; Chagin A; Sticht C; Yu X; van Gool SA; Pirzer H; Rappold GA; Gretz N; Wit JM; Savendahl L; Karperien M
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:373

Gender disproportion in children treated with growth hormone depends on country/region, diagnosis and severity of growth retardation

Savendahl L; Ross J; Fujieda K; Tajima T; Grueters A; Blankenstein O; Oliver I; Pienkowski C; Snajderova M; Peterkova V; Pedersen BT; Germak J; Rakov V
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:277-278

Resveratrol modulates longitudinal bone growth of cultured fetal rat metatarsal bones in a biphasic manner

Karimian E; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:372

Predictors of growth response after one year of Norditropin treatment in growth hormone deficient (GHD) patients from the ANSWER program® and NordiNet®

Ross J; Savendahl L; Karwe V; Rakov V; Germak J
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:372

Gender differences in growth hormone (GH) responsiveness in growth hormone deficient (GHD) children and short children born small for gestational age (SGA)

Ross J; Savendahl L; Grueters A; Oliver I; Peterkova V; Snajderova M; Germak J; Pedersen BT; Rakov V
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2009;72:372-373

Predictors of growth response after one year of Norditropin® treatment in Turner syndrome patients from the ANSWER program® and the NordiNet®

Ross J; Savendahl L; Karwe V; Germak J; Rakov V
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2008: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2008;p. 63-80

Growth Plate, Bone and Calcium

Chrysis D; Heino T; Sävendahl L
Letter: LEUKEMIA. 2008;22(4):883-884

Proteasome inhibition therapies in childhood cancer

Zaman F; Fadeel B; Savendahl L
Review: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2008;5(3):778-784

Hypercalcemia in children.

Benjamin RW; Moats-Staats BM; Calikoglu's A; Savendahl L; Chrysis D
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2008;23:S284

The Role of the G Protein-coupled Receptor GPR30 in Effects of Estrogen in Ovariectomized Mice.

Windahl SH; Andersson N; Chagin A; Martensson UE; Carlsten H; Olde B; Leeb-Lundberg LMF; Swanson C; Savendahl L; Lagerquist MK; Ohlsson C
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:37

Epiphyseal fusion in the human growth plate does not involve classical apoptosis

Emons J; Chagin AS; Hultenby K; Zhivotovsky B; Wit JM; Karperien M; Savendahl L
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2008;23:S53

Dexamethasone Triggers Mitochondrial Apoptosis Through Bax in Proliferative Growth Plate Chondrocytes Causing Growth Retardation

Zaman F; Chrysis D; Huntjens K; Takigawa M; Fadeel B; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:37-38

Proteasome inhibition causes permanent growth retardation in young mice

Eriksson E; Zaman F; Chrysis D; Savendahl L
Conference publication: CALCIFIED TISSUE INTERNATIONAL. 2008;82:S155

GPR30 estrogen receptor expression in bone cells during pubertal development

Heino TJ; Chagin AS; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:19

Time-dependent growth responsiveness to rhIGF-I in cultured rat metatarsal bones

Sundstrom K; Chagin AS; Camacho-Hubner C; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:9

Molecular regulation of the growth plate: Genome-wide expression analysis of human growth plate chondrocytes. An ESPE-RU update

Karperien M; Emons J; van Gool S; Chagin A; Savendahl L; Rappold G; Wit J-M
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:113

Efficacy and safety of bilateral epiphysiodesis performed in extremely tall girls and boys

Berner M; Wehtje H; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2008;70:88

Validation of authomated bone age determination in healthy American children of four ethnicities

Thodberg HH; Savendahl L
Other: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2007;5(2):680-685

Meeting Report:The 7th ESPE Growth Plate Working Group Symposium - EUROGROP June 27th 2007, Helsinki, Finland.

Miclea RL; Phillip M; Sävendahl L; Wit JM
Review: ACTA PAEDIATRICA. 2007;96(9):1275-1279

Oestrogen receptors and linear bone growth

Chagin AS; Savendahl L
Review: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2007;4(4):329-334

Estrogens and growth: review.

Chagin AS; Sävendahl L
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2007: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2007;p. 53-70

Growth Plate, Bone and Calcium

Chrysis D; Heino T; Sävendahl L
Conference publication: CALCIFIED TISSUE INTERNATIONAL. 2007;80:S130

Bisphosphonates stimulate linear growth of fetal rat metatarsal bones and protect chondrocytes from dexamethasone-induced apoptosis

Heino TJ; Chagin AS; Savendahl L
Other: PEDIATRIC ENDOCRINOLOGY REVIEWS PER. 2006;4(2):153-159

The Sixth ESPE Growth Plate Working Group Symposium (EUROGROP), June 30th, Rotterdam, the Netherlands, "a multidisciplinary approach to growth plate biology".

Emons J; Phillip M; Wit JM; Sävendahl L
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2006: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2006;p. 47-62

Growth Plate and Cellular Growth

Chagin A; Hagenäs L; Sävendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2006;65:28

Remaining estrogenic activity in the man with mutated estrogen receptor alpha [ERα)

Chagin A; Nilsson M; Wright KD; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2006;65:27-28

Estrogen induced VEGF-expression in the rat growth plate

Malmlof T; Chagin A; Tivesten A; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2006;65:28

Biologic response modifiers completely rescue cytokine-induced growth retardation in fetal rat metatarsal bones

Karimian E; Vojvodich PF; Savendahl L
Conference publication: HORMONE RESEARCH IN PAEDIATRICS. 2006;65:7-8

Cytokines and their effect on growth plate chondrocytes

Savendahl L
Book chapter: YEARBOOK OF PEDIATRIC ENDOCRINOLOGY 2005: YEARBOOK OF PAEDIATRIC ENDOCRINOLOGY. 2005;p. 47-62

Growth Plate and Cellular Growth

Chagin A; Dahlgren J; Sävendahl L
Other: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM. 2005;18(8):823-827

The 4th European Growth Plate Working Group Symposium (EUROGROP). 10th September 2004, Basel, Switzerland.

Chagin A; Phillip M; Wit J-M; Sävendahl L
Published conference paper: HORMONE RESEARCH IN PAEDIATRICS. 2005;64:94-97

Hormonal regulation of growth plate cartilage

Sävendahl L
Other: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM. 2004;17(4):685-694

The Third European Growth Plate Working Group Symposium. 17th September 2003, Ljubljana, Slovenia.

Robson H; Savendahl L; Phillip M; Wit J-M
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2004;19:S170

Additive stimulatory effects of estrogen and androgen receptor activation on trabecular bone in ovariectomized rats.

Moverare S; Tivesten Å; Chagin A; Venken K; Salmon P; Vanderschueren D; Sävendahl L; Holmäng A; Ohlsson C
Conference publication: PEDIATRIC RESEARCH. 2003;53(4):151A-152A

Raloxifene acts as an estrogen agonist on the rabbit growth plate

Nilsson O; Falk J; Ritzen ME; Baron J; Savendahl L
Letter: JOURNAL OF PEDIATRICS. 2002;140(1):140-141

Screening for Turner's syndrome by chromosome analysis of all girls with short stature -: Reply

Davenport ML; Sävendahl L
Published conference paper: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2000;74(5):383-386

Estrogens and human growth

Ritzén EM; Nilsson O; Grigelioniene G; Holst M; Sävendahl L; Wroblewski J
Published conference paper: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS, SUPPLEMENT. 1999;88(433):118-121

Turner syndrome: a pattern of early growth failure

Davenport ML; Punyasavatsut N; Gunther D; Savendahl L; Stewart PW
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Assessment of Bone Age using Artificial Intelligence in children and adolescents across different ethnicities

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1 January 2021 - 31 December 2023
Novel therapeutics for bone growth disorders targeting the growth plate

Swedish Research Council

1 January 2021 - 31 December 2024
Estrogen actions in growth plate cartilage

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1 January 2014 - 31 December 2015
Estrogen actions in growth plate cartilage

Swedish Research Council

1 January 2010 - 31 December 2012

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