Kun Qian

Publikationer
Populärvetenskap och samverkan

Artiklar

Journal article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2025;392(3):100664
Targeting the SFRP1 Interaction with ADAM10 for Therapeutic Discovery in Alzheimer's Disease
Lee H; Qian K; Li Q; Cary G; Carter G; Wiley J; Nwkamma R; Zoeller E; Betarbet R; Wen Z; Levey A; Du Y; Fu H
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(12):105382
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease
Du Y; Bradshaw WJ; Leisner TM; Annor-Gyamfi JK; Qian K; Bashore FM; Sikdar A; Nwogbo FO; Ivanov AA; Frye SV; Gileadi O; Brennan PE; Levey AI; Axtman AD; Pearce KH; Fu H; Katis VL
Journal article: JOURNAL OF MOLECULAR CELL BIOLOGY. 2023;15(3):mjad017
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
Cicka D; Niu Q; Qui M; Qian K; Miller E; Fan D; Mo X; Ivanov AA; Sarafianos SG; Du Y; Fu H
Journal article: ACTA PHARMACOLOGICA SINICA. 2022;43(9):2419-2428
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells.
Shu C; Zheng X; Wuhafu A; Cicka D; Doyle S; Niu Q; Fan D; Qian K; Ivanov AA; Du Y; Mo X; Fu H
Journal article: CELL. 2022;185(11):1974-1985.e12
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Mo X; Niu Q; Ivanov AA; Tsang YH; Tang C; Shu C; Li Q; Qian K; Wahafu A; Doyle SP; Cicka D; Yang X; Fan D; Reyna MA; Cooper LAD; Moreno CS; Zhou W; Owonikoko TK; Lonial S; Khuri FR; Du Y; Ramalingam SS; Mills GB; Fu H
Journal article: BIOORGANIC & MEDICINAL CHEMISTRY. 2021;45:116324
Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.
Yang X; Fan D; Troha AH; Ahn HM; Qian K; Liang B; Du Y; Fu H; Ivanov AA
Journal article: RSC MEDICINAL CHEMISTRY. 2021;12(1):95-102
Pharmacophore-based screening of diamidine small molecule inhibitors for protein arginine methyltransferases.
Qian K; Yan C; Su H; Dang T; Zhou B; Wang Z; Zhao X; Ivanov I; Ho M-C; Zheng YG
Journal article: ELIFE. 2019;8:e45403
The dynamic conformational landscape of the protein methyltransferase SETD8.
Chen S; Wiewiora RP; Meng F; Babault N; Ma A; Yu W; Qian K; Hu H; Zou H; Wang J; Fan S; Blum G; Pittella-Silva F; Beauchamp KA; Tempel W; Jiang H; Chen K; Skene RJ; Zheng YG; Brown PJ; Jin J; Luo C; Chodera JD; Luo M
Journal article: SCIENTIFIC REPORTS. 2019;9(1):1771
Downregulation of PRMT1 promotes the senescence and migration of a non-MYCN amplified neuroblastoma SK-N-SH cells.
Lee Y-J; Chang W-W; Chang C-P; Liu T-Y; Chuang C-Y; Qian K; Zheng YG; Li C
Journal article: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2018;3:6
Detection of PRMT1 inhibitors with stopped flow fluorescence.
Qian K; Hu H; Xu H; Zheng YG
Journal article: RSC MEDICINAL CHEMISTRY. 2017;8(2):440-444
Discovery of Decamidine as a New and Potent PRMT1 Inhibitor.
Zhang J; Qian K; Yan C; He M; Jassim BA; Ivanov I; Zheng YG
Journal article: ONCOTARGET. 2016;7(39):63629-63639
Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma.
Eberhardt A; Hansen JN; Koster J; Lotta LT; Wang S; Livingstone E; Qian K; Valentijn LJ; Zheng YG; Schor NF; Li X
Journal article: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2016;25(3):335-358
Small Molecule Inhibitors of Protein Arginine Methyltransferases.
Hu H; Qian K; Ho M-C; Zheng YG
Journal article: ELIFE. 2015;4:e07938
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Zhang L; Tran N-T; Su H; Wang R; Lu Y; Tang H; Aoyagi S; Guo A; Khodadadi-Jamayran A; Zhou D; Qian K; Hricik T; Côté J; Han X; Zhou W; Laha S; Abdel-Wahab O; Levine RL; Raffel G; Liu Y; Chen D; Li H; Townes T; Wang H; Deng H; Zheng YG; Leslie C; Luo M; Zhao X
Journal article: NATURE CHEMICAL BIOLOGY. 2014;10(5):328-330
Labeling: palladium brings proteins to life.
Qian K; Zheng YG
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2014;57(6):2611-2622
Diamidine compounds for selective inhibition of protein arginine methyltransferase 1.
Yan L; Yan C; Qian K; Su H; Kofsky-Wofford SA; Lee W-C; Zhao X; Ho M-C; Ivanov I; Zheng YG

Alla övriga publikationer

Book chapter: HIGH CONTENT IMAGING IN DRUG DISCOVERY. 2025;p. 168-208
High Content Imaging Applications of Advanced and Translational Disease Models in Drug Discovery and Development
Cui W; Haffa M; Massai F; Qian K; Vallin M; Axelsson H; Seashore-Ludlow B
Preprint: BIORXIV. 2023;BIORXIV
Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
Du Y; Bradshaw WJ; Leisner TM; Annor-Gyamfi JK; Qian K; Bashore FM; Sikdar A; Nwogbo FO; Ivanov AA; Frye SV; Gileadi O; Brennan PE; Levey AI; Emory-Sage-SGC TREAT-AD Center; Axtman AD; Pearce KH; Fu H; Katis VL
Book chapter: EPI-INFORMATICS. 2016;p. 231-256
Current Development of Protein Arginine Methyltransferase Inhibitors
Qian K; George Zheng Y

Artiklar

Alla övriga publikationer

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