Karin Dahlman-Wright

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Jag är professor i molekylär endokrinologi och utsågs till prorektor vid Karolinska Institutet fr.o.m. den 1 januari 2016. Den 18 februari 2016 utsågs jag av regeringen till Karolinska Institutets vikarierande rektor, för att den 1 augusti 2017 återgå till min befattning som prorektor. Tjänsten som prorektor avslutades 9 september 2019. 2009 tom augusti 2015 var jag prefekt vid institutionen för biovetenskaper och näringslära och 2015 var jag vicedekan med ansvar för infrastrukturfrågor.

Mellan september 2013 och juni 2015 var jag KI Scientific Director, SciLifeLab, med speciellt ansvar för de nationella plattformarna och ingick i SciLifeLabs operationella ledning. 2001 grundade jag BEA, en core facilitet som tillhandahåller avancerade tjänster inom området genomik och bioinformatik. 1994-2000 innehade jag linjechefs- och projektledar- befattningar vid Pharmacia och Upjohn. Jag deltar i det strategiska forskningsområdet inom Diabetes vid KI.

Utbildning
Doktor Medicinsk Vetenskap, Karolinska Institutet, 1991

Docent i Molekylär Endokrinologi, Karolinska Institutet, 1996

Forskningsbeskrivning

Min forskning fokuserar på studier av östrogen signalering med specifikt fokus på typ 2 diabetes och bröstcancer. Vi studerar fenotyper hos musmodeller med vävnadsselektiv knock-out av östrogen receptorer och relaterar detta till molekylära förändringar av exempelvis globalt genuttryck. Vi använder olika cellmodeller för bröstcancer och teknologier inom funktionsgenomik, ChIP SEQ, global genuttrycksanalys och proteomik för att identifiera signalvägar som kan fungera som möjliga mål för behandling av bröstcancer.

Artiklar

Article: ONCOGENE. 2018;37(19):2586-2600
c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer
He H; Sinha I; Fan R; Haldosen L-A; Yan F; Zhao C; Dahlman-Wright K
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2018;103(2):710-721
Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance
Petrus P; Bialesova L; Checa A; Kerr A; Naz S; Backdahl J; Gracia A; Toft S; Dahlman-Wright K; Heden P; Dahlman I; Wheelock CE; Arner P; Mejhert N; Gao H; Ryden M
Article: ONCOTARGET. 2017;8(44):76622-76633
Estrogen receptor β2 induces proliferation and invasiveness of triple negative breast cancer cells; association with regulation of PHD3 and HIF-1α
Bialesova L; Xu L; Gustafsson J-A; Haldosen L-A; Zhao C; Dahlman-Wright K
Article: SCIENTIFIC REPORTS. 2017;7(1):10152
Epigenetic Regulation of PLIN1 in Obese Women and its Relation to Lipolysis
Bialesova L; Kulyte A; Petrus P; Sinha I; Laurencikiene J; Zhao C; Wright KD; Arner P; Dahlman I
Article: ACTA PHYSIOLOGICA. 2017;219(2):486-493
Expression of sex steroid hormone receptors in human skeletal muscle during the menstrual cycle
Ekenros L; Papoutsi Z; Friden C; Wright KD; Hirschberg AL
Article: ONCOTARGET. 2016;7(44):71580-71593
Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells
Diao Y; Azatyan A; Rahman MF-U; Zhao C; Zhu J; Dahlman-Wright K; Zaphiropoulos PG
Article: CANCER RESEARCH. 2016;76(19):5634-5646
Estrogen Receptor a Promotes Breast Cancer by Reprogramming Choline Metabolism
Jia M; Andreassen T; Jensen L; Bathen TF; Sinha I; Gao H; Zhao C; Haldosen L-A; Cao Y; Girnita L; Moestue SA; Dahlman-Wright K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(29):15169-15184
Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes
Martinez-Redondo V; Jannig PR; Correia JC; Ferreira DMS; Cervenka I; Lindvall JM; Sinha I; Izadi M; Pettersson-Klein AT; Agudelo LZ; Gimenez-Cassina A; Brum PC; Dahlman-Wright K; Ruas JL
Article: ONCOGENE. 2016;35(15):1955-1964
RING finger protein 31 promotes p53 degradation in breast cancer cells
Zhu J; Zhao C; Zhuang T; Jonsson P; Sinha I; Williams C; Stromblad S; Dahlman-Wright K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(10):5068-5079
AP-1 Is a Key Regulator of Proinflammatory Cytokine TNF α-mediated Triple-negative Breast Cancer Progression
Qiao Y; He H; Jonsson P; Sinha I; Zhao C; Dahlman-Wright K
Article: MOLECULAR METABOLISM. 2016;5(3):171-183
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients
Kirchner H; Sinha I; Gao H; Ruby MA; Schonke M; Lindvall JM; Barres R; Krook A; Naslund E; Dahlman-Wright K; Zierath JR
Article: MOLECULAR BIOLOGY REPORTS. 2016;43(3):141-150
The transcriptional coregulator MAML1 affects DNA methylation and gene expression patterns in human embryonic kidney cells
Putnik M; Brodin D; Wojdacz TK; Fagerstrom-Billai F; Dahlman-Wright K; Wallberg AE
Article: PLOS ONE. 2016;11(10):e0164241
Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERa in Breast Cancer Cells
Gonzalez-Bengtsson A; Asadi A; Gao H; Dahlman-Wright K; Jacobsson A
Article: OBESITY. 2016;24(1):250-261
Differential methylation in inflammation and type 2 diabetes genes in siblings born before and after maternal bariatric surgery
Berglind D; Muller P; Willmer M; Sinha I; Tynelius P; Naslund E; Dahlman-Wright K; Rasmussen F
Article: ONCOTARGET. 2015;6(41):43853-43868
p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells
Zhuang T; Zhu J; Li Z; Lorent J; Zhao C; Dahlman-Wright K; Stromblad S
Article: MOLECULAR METABOLISM. 2015;4(12):891-902
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism
Correia JC; Massart J; de Boer JF; Porsmyr-Palmertz M; Martinez-Redondo V; Agudelo LZ; Sinha I; Meierhofer D; Ribeiro V; Bjornholm M; Sauer S; Dahlman-Wright K; Zierath JR; Groen AK; Ruas JL
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;466(4):650-655
Identification of proteins highly expressed in uterine fluid from mice with hydrometra
Antonson P; Nalvarte I; Varshney M; Xu L; Windahl SH; Humire P; Ohlsson C; Gustafsson J-A; Dahlman-Wright K
Article: ONCOTARGET. 2015;6(32):33623-33635
Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells
Borbely G; Haldosen L-A; Dahlman-Wright K; Zhao C
Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2015;29(4):557-568
Estrogen receptor alpha and beta in health and disease
Jia M; Dahlman-Wright K; Gustafsson J-A
Article: INTERNATIONAL JOURNAL OF OBESITY. 2015;39(6):910-919
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
Dahlman I; Sinha I; Gao H; Brodin D; Thorell A; Ryden M; Andersson DP; Henriksson J; Perfilyev A; Ling C; Dahlman-Wright K; Arner P
Article: ONCOTARGET. 2015;6(10):7804-7814
AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial-mesenchymal transition in triple-negative breast cancer
Qiao Y; Shiue C-N; Zhu J; Zhuang T; Jonsson P; Wright APH; Zhao C; Dahlman-Wright K
Article: CLINICAL EPIGENETICS. 2015;7(1):93
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women
Arner P; Sinha I; Thorell A; Ryden M; Dahlman-Wright K; Dahlman I
Article: ONCOGENE. 2014;33(34):4340-4351
The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation
Zhu J; Zhao C; Kharman-Biz A; Zhuang T; Jonsson P; Liang N; Williams C; Lin C-Y; Qiao Y; Zendehdel K; Stroemblad S; Treuter E; Dahlman-Wright K
Article: CANCER RESEARCH. 2014;74(14):3983-3994
Genome-wide Profiling of AP-1-Regulated Transcription Provides Insights into the Invasiveness of Triple-Negative Breast Cancer
Zhao C; Qiao Y; Jonsson P; Wang J; Xu L; Rouhi P; Sinha I; Cao Y; Williams C; Dahlman-Wright K
Article: CELL METABOLISM. 2014;19(6):981-992
Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue
Gao H; Mejhert N; Fretz JA; Arner E; Lorente-Cebrian S; Ehrlund A; Dahlman-Wright K; Gong X; Stromblad S; Douagi I; Laurencikiene J; Dahlman I; Daub CO; Ryden M; Horowitz MC; Arner P
Article: BREAST CANCER RESEARCH. 2014;16(1):R21
Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines
Rizza P; Barone I; Zito D; Giordano F; Lanzino M; De Amicis F; Mauro L; Sisci D; Catalano S; Wright KD; Gustafsson J-A; Ando S
Article: PLOS ONE. 2014;9(1):e85581
aP2-Cre-Mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra
Antonson P; Matic M; Portwood N; Kuiper RV; Bryzgalova G; Gao H; Windahl SH; Humire P; Ohlsson C; Berggren P-O; Gustafsson J-A; Dahlman-Wright K
Article: BMC CANCER. 2013;13:441
Expression of activator protein-1 (AP-1) family members in breast cancer
Kharman-Biz A; Gao H; Ghiasvand R; Zhao C; Zendehdel K; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(6):2294-2299
Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice
Windahl SH; Borjesson AE; Farman HH; Engdahl C; Moverare-Skrtic S; Sjogren K; Lagerquist MK; Kindblom JM; Koskela A; Tuukkanen J; Pajevic PD; Feng JQ; Dahlman-Wright K; Antonson P; Gustafsson J-A; Ohlsson C
Article: PLOS ONE. 2013;8(2):e57458
Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action
Matic M; Bryzgalova G; Gao H; Antonson P; Humire P; Omoto Y; Portwood N; Pramfalk C; Efendic S; Berggren P-O; Gustafsson J-A; Dahlman-Wright K
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2012;49(3):277-287
Estrogen receptor-α, RBCK1, and protein kinase C β 1 cooperate to regulate estrogen receptor-α gene expression
Sheppard NG; Heldring N; Dahlman-Wright K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;426(1):26-32
Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells
Putnik M; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: CARCINOGENESIS. 2012;33(9):1684-1691
Interplay between AP-1 and estrogen receptor in regulating gene expression and proliferation networks in breast cancer cells
Dahlman-Wright K; Qiao Y; Jonsson P; Gustafsson J-A; Williams C; Zhao C
Article: DIABETES. 2012;61(8):1986-1993
Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity
Arner E; Mejhert N; Kulyte A; Balwierz PJ; Pachkov M; Cormont M; Lorente-Cebrian S; Ehrlund A; Laurencikiene J; Heden P; Dahlman-Wright K; Tanti J-F; Hayashizaki Y; Ryden M; Dahlman I; van Nimwegen E; Daub CO; Arner P
Article: SHOCK. 2012;37(4):355-359
GENE EXPRESSION OF ESTROGEN RECEPTORS IN PBMC FROM PATIENTS WITH PUUMALA VIRUS INFECTION
Brundin P; Zhao C; Dahlman-Wright K; Ahlm C; Evengard B
Article: GENOME BIOLOGY. 2012;13(3):R24
The Transcription Factor Encyclopedia
Yusuf D; Butland SL; Swanson MI; Bolotin E; Ticoll A; Cheung WA; Zhang XYC; Dickman CTD; Fulton DL; Lim JS; Schnabl JM; Ramos OHP; Vasseur-Cognet M; de Leeuw CN; Simpson EM; Ryffel GU; Lam EW-F; Kist R; Wilson MSC; Marco-Ferreres R; Brosens JJ; Beccari LL; Bovolenta P; Benayoun BA; Monteiro LJ; Schwenen HDC; Grontved L; Wederell E; Mandrup S; Veitia RA; Chakravarthy H; Hoodless PA; Mancarelli MM; Torbett BE; Banham AH; Reddy SP; Cullum RL; Liedtke M; Tschan MP; Vaz M; Rizzino A; Zannini M; Frietze S; Farnham PJ; Eijkelenboom A; Brown PJ; Laperriere D; Leprince D; de Cristofaro T; Prince KL; Putker M; del Peso L; Camenisch G; Wenger RH; Mikula M; Rozendaal M; Mader S; Ostrowski J; Rhodes SJ; Van Rechem C; Boulay G; Olechnowicz SWZ; Breslin MB; Lan MS; Nanan KK; Wegner M; Hou J; Mullen RD; Colvin SC; Noy PJ; Webb CF; Witek ME; Ferrell S; Daniel JM; Park J; Waldman SA; Peet DJ; Taggart M; Jayaraman P-S; Karrich JJ; Blom B; Vesuna F; O'Geen H; Sun Y; Gronostajski RM; Woodcroft MW; Hough MR; Chen E; Europe-Finner GN; Karolczak-Bayatti M; Bailey J; Hankinson O; Raman V; LeBrun DP; Biswal S; Harvey CJ; DeBruyne JP; Hogenesch JB; Hevner RF; Heligon C; Luo XM; Blank MC; Millen KJ; Sharlin DS; Forrest D; Dahlman-Wright K; Zhao C; Mishima Y; Sinha S; Chakrabarti R; Portales-Casamar E; Sladek FM; Bradley PH; Wasserman WW
Article: NEUROTOXICOLOGY AND TERATOLOGY. 2011;33(6):752-764
Developmental toxicity of the environmental pollutant 4-nonylphenol in zebrafish
Chandrasekar G; Arner A; Kitambi SS; Dahlman-Wright K; Lendahl MA
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2011;26(3):431-439
Study of Estrogen Receptor-α and Receptor-β Gene Polymorphisms on Alzheimer's Disease
Goumidi L; Dahlman-Wright K; Tapia-Paez I; Matsson H; Pasquier F; Amouyel P; Kere J; Lambert J-C; Meirhaeghe A
Article: BMC MEDICAL GENOMICS. 2011;4:51
Genome wide association study identifies KCNMA1 contributing to human obesity
Jiao H; Arner P; Hoffstedt J; Brodin D; Dubern B; Czernichow S; van't Hooft F; Axelsson T; Pedersen O; Hansen T; Sorensen TIA; Hebebrand J; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(6):E962-E966
Genetic Association and Gene Expression Analysis Identify FGFR1 as a New Susceptibility Gene for Human Obesity
Jiao H; Arner P; Dickson SL; Vidal H; Mejhert N; Henegar C; Taube M; Hansson C; Hinney A; Galan P; Simon C; Silveira A; Benrick A; Jansson J-O; Bouloumie A; Langin D; Laville M; Debard C; Axelsson T; Ryden M; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: PLOS ONE. 2010;5(12):e15594
Fatty Acids Derived from Royal Jelly Are Modulators of Estrogen Receptor Functions
Moutsatsou P; Papoutsi Z; Kassi E; Heldring N; Zhao C; Tsiapara A; Melliou E; Chrousos GP; Chinou I; Karshikoff A; Nilsson L; Dahlman-Wright K
Article: CURRENT OPINION IN PHARMACOLOGY. 2010;10(6):692-697
Molecular biology and functional genomics of liver X receptors (LXR) in relationship to metabolic diseases
Faulds MH; Zhao C; Dahlman-Wright K
Article: PLOS ONE. 2010;5(11):e14085
Gene Expression Profiling and Chromatin Immunoprecipitation Identify DBN1, SETMAR and HIG2 as Direct Targets of SOX11 in Mantle Cell Lymphoma
Wang X; Bjoerklund S; Wasik AM; Grandien A; Andersson P; Kimby E; Dahlman-Wright K; Zhao C; Christensson B; Sander B
Article: CANCER RESEARCH. 2010;70(12):5174-5183
Genome-Wide Mapping of Estrogen Receptor-β-Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
Zhao C; Gao H; Liu Y; Papoutsi Z; Jaffrey S; Gustafsson J-A; Dahlman-Wright K
Article: BRITISH JOURNAL OF CANCER. 2010;102(10):1541-1548
Adipose tissue pathways involved in weight loss of cancer cachexia
Dahlman I; Mejhert N; Linder K; Agustsson T; Mutch DM; Kulyte A; Isaksson B; Permert J; Petrovic N; Nedergaard J; Sjoelin E; Brodin D; Clement K; Dahlman-Wright K; Ryden M; Arner P
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(4):471-478
Genomic landscape of positive natural selection in Northern European populations
Lappalainen T; Salmela E; Andersen PM; Dahlman-Wright K; Sistonen P; Savontaus M-L; Schreiber S; Lahermo P; Kere J
Article: CANCER RESEARCH. 2010;70(3):1265-1274
RBCK1 Drives Breast Cancer Cell Proliferation by Promoting Transcription of Estrogen Receptor α and Cyclin B1
Gustafsson N; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: ENDOCRINE. 2009;36(2):224-232
Microarray analysis of altered gene expression in ERβ-overexpressing HEK293 cells
Zhao C; Putnik M; Gustafsson J-A; Dahlman-Wright K
Article: BMC GENETICS. 2009;10:55
Effects of two common polymorphisms in the 3′ untranslated regions of estrogen receptor β on mRNA stability and translatability
Putnik M; Zhao C; Gustafsson J-A; Dahlman-Wright K
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2009;43(1-2):65-72
Binding of estrogen receptor α/β heterodimers to chromatin in MCF-7 cells
Papoutsi Z; Zhao C; Putnik M; Gustafsson J-A; Dahlman-Wright K
Article: PLOS ONE. 2009;4(6):e5805
Gene expression in peripheral blood leukocytes in monozygotic twins discordant for chronic fatigue: no evidence of a biomarker.
Byrnes A; Jacks A; Dahlman-Wright K; Evengard B; Wright FA; Pedersen NL; Sullivan PF
Article: BMC MEDICAL GENETICS. 2009;10:27
Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles - a cohort study
Dahlman I; Nilsson M; Gu HF; Lecoeur C; Efendic S; Ostenson CG; Brismar K; Gustafsson J-A; Froguel P; Vaxillaire M; Dahlman-Wright K; Steffensen KR
Article: JOURNAL OF ENDOCRINOLOGY. 2008;199(2):275-286
The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms
Lundholm L; Bryzgalova G; Gao H; Portwood N; Falt S; Berndt KD; Dicker A; Galuska D; Zierath IR; Gustafsson JA; Efendic S; Dahlman-Wright K; Khan A
Article: PHARMACOGENETICS AND GENOMICS. 2008;18(11):967-975
Estrogen receptor alpha gene variants associate with type 2 diabetes and fasting plasma glucose
Dahlman I; Vaxillaire M; Nilsson M; Lecoeur C; Gu HF; Cavalcanti-Proenca C; Efendic S; Ostenson CG; Brismar K; Charpentler G; Gustafsson J-A; Froguel P; Dahlman-Wright K; Steffensen KR
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2008;295(4):E904-E912
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice
Bryzgalova G; Lundholm L; Portwood N; Gustafsson J-A; Khan A; Efendic S; Dahlman-Wright K
Article: FERTILITY AND STERILITY. 2008;90(1):44-48
Key lipogenic gene expression can be decreased by estrogen in human adipose tissue
Lundholm L; Zang H; Hirschberg AL; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: JOURNAL OF ENDOCRINOLOGY. 2008;196(3):547-557
Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue:: target genes include glutathione peroxidase 3 and cell death-inducing, DNA fragmentation factor, α-subunit-like effector A
Lundholm L; Putnik M; Otsukil M; Andersson S; Ohisson C; Gustafsson J-A; Dahlman-Wright K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(7):2604-2609
The genome landscape of ERα- and ERβ-binding DNA regions
Liu Y; Gao H; Marstrand TT; Strom A; Valen E; Sandelin A; Gustafsson J-A; Dahlman-Wright K
Article: MOLECULAR ENDOCRINOLOGY. 2008;22(1):10-22
Genome-wide identification of estrogen receptor α-binding sites in mouse liver
Gao H; Falt S; Sandelin A; Gustafsson J-A; Dahlman-Wright K
Article: PLOS ONE. 2008;3(10):e3519
Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe
Salmela E; Lappalainen T; Fransson I; Andersen PM; Dahlman-Wright K; Fiebig A; Sistonen P; Savontaus M-L; Schreiber S; Kere J; Lahermo P
Article: BMC MEDICAL GENETICS. 2007;8:73
Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis - a cohort study
Nilsson M; Dahlman I; Jiao H; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: FERTILITY AND STERILITY. 2007;88(1):100-106
Effects of testosterone and estrogen treatment on lipolysis signaling pathways in subcutaneous adipose tissue of postmenopausal women
Zang H; Ryden M; Wahlen K; Dahlman-Wright K; Arner P; Hirschberg AL
Article: INTERNATIONAL JOURNAL OF OBESITY. 2007;31(6):900-907
Oestrogen receptor α gene expression levels are reduced in obese compared to normal weight females
Nilsson M; Dahlman I; Ryden M; Nordstrom EA; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: CANCER RESEARCH. 2007;67(8):3955-3962
Estrogen receptor β2 negatively regulates the transactivation of estrogen receptor α in human breast cancer cells
Zhao C; Matthews J; Tujague M; Wan J; Strom A; Toresson G; Lam EW-F; Cheng G; Gustafsson J-A; Dahlman-Wright K
Article: JOURNAL OF CLINICAL PATHOLOGY. 2007;60(2):195-198
Reduced levels of oestrogen receptor β mRNA in Swedish patients with chronic fatigue syndrome
Grans H; Nilsson M; Dahlman-Wright K; Evengard B
Article: NUCLEIC ACIDS RESEARCH (NAR). 2007;35(14):4858-4868
Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter
Nilsson M; Dahlman-Wright K; Karelmo C; Gustafsson J-A; Steffensen KR
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(12):881-889
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity
Dahlman I; Nilsson M; Jiao H; Hoffstedt J; Lindgren CM; Humphreys K; Kere J; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: INFLAMMATION RESEARCH. 2006;55(8):349-353
Estrogen attenuates vascular expression of inflammation associated genes and adhesion of monocytes to endothelial cells
Gao H; Liang M; Bergdahl A; Hamren A; Lindholm MW; Dahlman-Wright K; Nilsson B-O
Article: CLIMACTERIC. 2006;9(3):215-223
Evidence for associations between common polymorphisms of estrogen receptor β gene with homocysteine and nitric oxide
Reimann M; Vafeiadou K; Hall WL; Dierkes J; Nilsson M; Dahlman-Wright K; Ferrari M; Huebner U; Hallund J; Bugel S; Branca F; Wilhams CM; Koebnick C
Article: MOLECULAR ENDOCRINOLOGY. 2006;20(6):1287-1299
Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: A possible mechanism is through direct regulation of signal transducer and activator of transcription 3
Gao H; Bryzgalova G; Hedman E; Khan A; Efendic S; Gustafsson JA; Dahlman-Wright K
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(5):379-383
Functional characterization of a novel variant of estrogen receptor beta identified in screening of DNA derived from African Americans
Zhao C; Gustafsson J; Dahlman-Wright K
Article: CLINICAL CANCER RESEARCH. 2006;12(6):1936-1941
Estrogen receptor β polymorphism is associated with prostate cancer risk
Thellenberg-Karlsson C; Lindström S; Malmer B; Wiklund F; Augustsson-Bälter K; Adami HO; Stattin P; Nilsson M; Dahlman-Wright K; Gustafsson J; Grönberg H
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2006;83(3):592-600
Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women:: interactions with genotype and equol production
Hall WL; Vafeiadou K; Hallund J; Bugel S; Reimann M; Koebnick C; Zunft HJF; Ferrari M; Branca F; Dadd T; Talbot D; Powell J; Minihane AM; Cassidy A; Nilsson M; Dahlman-Wright K; Gustafsson J; Williams CM
Article: DIABETOLOGIA. 2006;49(3):588-597
Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice:: insulin sensitivity in the liver
Bryzgalova G; Gao H; Ahren B; Zierath JR; Galuska D; Steiler TL; Dahlman-Wright K; Nilsson S; Gustafsson J; Efendic S; Khan A
Article: DISEASES OF THE ESOPHAGUS. 2006;19(1):20-23
Genes associated with telomerase activity levels in esophageal carcinoma cell lines.
Bergqvist M; Brattström D; Brodin D; Lindkvist A; Dahlman-Wright K; Dreilich M; Wagenius G; Paulsson-Karlsson Y
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2005;82(6):1260-1268
Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women:: interactions with genotype and equol production
Hall WL; Vafeiadou K; Hallund J; Bügel S; Koebnick C; Reimann M; Ferrari M; Branca F; Talbot D; Dadd T; Nilsson M; Dahlman-Wright K; Gustafsson J; Minihane AM; Williams CM
Article: JOURNAL OF MEDICAL GENETICS. 2005;42(11):847-851
Global analysis of uniparental disomy using high density genotyping arrays
Bruce S; Leinonen R; Lindgren CM; Kivinen K; Dahlman-Wright K; Lipsanen-Nyman M; Hannula-Jouppi K; Kere J
Article: JOURNAL OF PATHOLOGY. 2005;207(1):91-101
Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling
Sun XJ; Wei L; Lidén J; Hui G; Dahlman-Wright K; Hjerpe A; Dobra K
Article: BIOCHEMISTRY. 2005;44(22):7936-7944
Mouse estrogen receptor β isoforms exhibit differences in ligand selectivity and coactivator recruitment
Zhao CY; Toresson G; Xu L; Koehler KF; Gustafsson J; Dahlman-Wright K
Article: EXPERIMENTAL ONCOLOGY. 2005;27(2):102-107
Radiation-induced DNA-damage and gene expression profiles in human lung cancer cells with different radiosensitivity
Hellman B; Brodin D; Andersson M; Dahlman-Wright K; Isacsson U; Brattström D; Bergqvist M
Article: MOLECULAR PHARMACOLOGY. 2005;67(3):815-826
Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-κB and activator protein-1 repression
Bladh LG; Lidén J; Dahlman-Wright K; Reimers M; Nilsson S; Okret S
Article: MOLECULAR ENDOCRINOLOGY. 2005;19(3):632-643
Identification of target genes involved in the antiproliferative effect of glucocorticoids reveals a role for nuclear factor-κB repression
Bladh LG; Lidén J; Pazirandeh A; Rafter I; Dahlman-Wright K; Nilsson S; Okret S
Article: ENDOCRINOLOGY. 2004;145(12):5525-5531
Estrogen up-regulates hepatic expression of suppressors of cytokine signaling-2 and -3 in vivo and in vitro
Leong GM; Moverare S; Brce J; Doyle N; Sjögren K; Dahlman-Wright K; Gustafsson J; Ho KKY; Ohlsson C; Leung KC
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;287(6):E1125-E1131
Difference in skeletal muscle function in males vs. females:: role of estrogen receptor-β
Glenmark B; Nilsson M; Gao H; Gustafsson J; Dahlman-Wright K; Westerblad H
Article: CARCINOGENESIS. 2004;25(11):2067-2073
Identification of a functional variant of estrogen receptor beta in an African population
Zhao CY; Xu L; Otsuki M; Toresson G; Koehler K; Pan-Hammarström Q; Hammarström L; Nilsson S; Gustafsson J; Dahlman-Wright K
Article: HUMAN MOLECULAR GENETICS. 2004;13(15):1551-1561
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus
Elomaa O; Majuri I; Suomela S; Asumalahti K; Jiao H; Mirzaei Z; Rozell B; Dahlman-Wright K; Pispa J; Kere J; Saarialho-Kere U
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2004;151(2):259-263
Estrogen increases coagulation factor V mRNA levels via both estrogen receptor-α and -β in murine bone marrow/bone
Movérare S; Skrtic S; Lindberg MK; Dahlman-Wright K; Ohlsson C
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2004;32(3):879-892
Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue
Lundholm L; Movérare S; Steffensen KR; Nilsson M; Otsuki M; Ohlsson C; Gustafsson J; Dahlman-Wright K
Article: PROTEIN EXPRESSION AND PURIFICATION. 2004;35(2):190-198
Purification of functional full-length liver X receptor β produced in Escherichia coli
Toresson G; Schuster GU; Steffensen KR; Bengtsson M; Ljunggren J; Dahlman-Wright K; Gustafsson J
Article: MOLECULAR PSYCHIATRY. 2004;9(1):28-34
Association of estrogen receptor β gene polymorphisms with bulimic disease in women
Nilsson M; Naessén S; Dahlman I; Hirschberg AL; Gustafsson JA; Dahlman-Wright K
Article: ONCOGENE. 2003;22(48):7600-7606
Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer:: regulation by methylation
Zhao CY; Lam EWF; Sunters A; Enmark E; De Bella MT; Coombes RC; Gustafsson J; Dahlman-Wright K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;310(2):589-593
Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors α and β, respectively
Steffensen KR; Nilsson M; Schuster GU; Stulnig TM; Dahlman-Wright K; Gustafsson J
Article: MOLECULAR ENDOCRINOLOGY. 2003;17(9):1844-1855
Specific regulation of lipocalin-type prostaglandin D synthase in mouse heart by estrogen receptor β
Otsuki M; Gao H; Dahlman-Wright K; Ohlsson C; Eguchi N; Urade Y; Gustafsson J
Article: ENDOCRINOLOGY. 2003;144(8):3541-3546
Human estrogen receptor β 548 is not a common variant in three distinct populations
Xu L; Pan-Hammarström Q; Försti A; Hemminki K; Hammarström L; Labuda D; Gustafsson J; Dahlman-Wright K
Article: BREAST CANCER RESEARCH AND TREATMENT. 2003;79(3):409-413
Polymorphisms in the estrogen receptor beta gene and risk of breast cancer:: no association
Försti A; Zhao CY; Israelsson E; Dahlman-Wright K; Gustafsson J; Hemminki K
Article: MOLECULAR ENDOCRINOLOGY. 2003;17(2):203-208
Estrogen receptor (ER)-β reduces ERα-regulated gene transcription, supporting a "Ying Yang" relationship between ERα and ERβ in mice
Lindberg MK; Movérare S; Skrtic S; Gao H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: NUCLEAR RECEPTOR SIGNALING. 2003;1:e003-nrs.01003
Cardiovascular roles of estrogen receptors: insights gained from knockout models.
Otsuki M; Dahlman-Wright K; Gustafsson J-A
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2002;17(12):2183-2195
Identification of estrogen-regulated genes of potential importance for the regulation of trabecular bone mineral density
Lindberg MK; Movérare S; Eriksson AL; Skrtic S; Gao H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: MOLECULAR PHARMACOLOGY. 2002;62(6):1299-1305
Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue
Stulnig TM; Steffensen KR; Gao H; Reimers M; Dahlman-Wright K; Schuster GU; Gustafsson J
Article: JOURNAL OF ENDOCRINOLOGY. 2002;174(2):167-178
Estrogen receptor specificity for the effects of estrogen in ovariectomized mice
Lindberg MK; Weihua Z; Andersson N; Movérare S; Gao H; Vidal O; Erlandsson M; Windahl S; Andersson G; Lubahn DB; Carlsten H; Dahlman-Wright K; Gustafsson J; Ohlsson C
Article: BIOCHEMISTRY. 2001;40(20):5861-5869
Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4).
Weigelt J; Climent I; Dahlman-Wright K; Wikström M
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 1999;22(3):313-325
Selective activation of the probasin androgen-responsive region by steroid hormones
Kasper S; Rennie PS; Bruchovsky N; Lin L; Cheng H; Snoek R; Dahlman-Wright K; Gustafsson J; Shiu RPC; Sheppard PC; Matusik RJ
Article: MOLECULAR PHARMACOLOGY. 1995;48(5):938-945
Zinc ions antagonize the inhibitory effect of aurothiomalate on glucocorticoid receptor function at physiological concentrations.
Tanaka H; Makino Y; Dahlman-Wright K; Gustafsson JA; Okamoto K; Makino I; Wright KD [corrected to Dahlman-Wright K
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Corrigendum: ONCOGENE. 2019;38(2):299-300
The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation (vol 33, pg 4340, 2018)
Zhu J; Zhao C; Kharman-Biz A; Zhuang T; Jonsson P; Liang N; Williams C; Lin C-Y; Qiao Y; Zendehdel K; Stromblad S; Treuter E; Dahlman-Wright K
Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2014;382(1):665-672
Estrogen receptor beta in breast cancer
Haldosen L-A; Zhao C; Dahlman-Wright K
Review: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION. 2013;15(3):81-90
Implications of estrogen receptor alpha and estrogen receptor beta for adipose tissue functions and cardiometabolic complications.
Gao H; Dahlman-Wright K
Review: JOURNAL OF ENDOCRINOLOGY. 2012;212(1):3-12
The diversity of sex steroid action: regulation of metabolism by estrogen signaling
Faulds MH; Zhao C; Dahlman-Wright K; Gustafsson J-A
Review: CURRENT OPINION IN ONCOLOGY. 2012;24(1):58-61
Metabolic diseases and cancer risk
Faulds MH; Dahlman-Wright K
Published conference paper: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2011;27(7):697-704
Early transcriptional regulation by C-peptide in freshly isolated rat proximal tubular cells
Lindahl E; Nordquist L; Muller P; El Agha E; Friederich M; Dahlman-Wright K; Palm F; Jornvall H
Editorial comment: EMBO JOURNAL. 2011;30(13):2516-2517
From DNA binding to metabolic control: integration of -omics data reveals drug targets for prostate cancer
Gao H; Dahlman-Wright K
Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2011;334(1-2):83-90
The gene regulatory networks controlled by estrogens
Gao H; Dahlman-Wright K
Review: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(51):39575-39579
Estrogen Signaling via Estrogen Receptor β
Zhao C; Dahlman-Wright K; Gustafsson J-A
Review: JOURNAL OF ENDOCRINOLOGY. 2010;204(3):233-240
Liver X receptor in cholesterol metabolism
Zhao C; Dahlman-Wright K
Review: NUCLEAR RECEPTOR SIGNALING. 2008;6:e003
Estrogen receptor beta: an overview and update.
Zhao C; Dahlman-Wright K; Gustafsson J-A
Review: PHARMACOLOGICAL REVIEWS. 2006;58(4):773-781
International Union of Pharmacology.: LXIV.: Estrogen receptors
Dahlman-Wright K; Cavailles V; Fuqua SA; Jordan VC; Katzenellenbogen JA; Korach KS; Maggi A; Muramatsu M; Parker MG; Gustafsson J-A
Review: ESSAYS IN BIOCHEMISTRY. 2004;40:157-167
Nuclear receptors in disease:: the oestrogen receptors
Nilsson M; Dahlman-Wright K; Gustafsson J
Letter: JOURNAL OF BIOMOLECULAR NMR. 2000;17(2):181-182
1H, 13C and 15N resonance assignments of the DNA binding domain of the human forkhead transcription factor AFX.
Weigelt J; Climent I; Dahlman-Wright K; Wikström M

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