Karin Dahlman-Wright
Specialist | Docent
E-mail: karin.dahlman-wright@ki.se
Telephone: +46852481089
Visiting address: Nobels väg 6, 17165 Solna
Postal address: GVS Gemensamt verksamhetsstöd, GVS Fakultetskansliet och internationella relationer, 171 77 Stockholm
Part of:
About me
- I am professor of molecular endocrinology and was made Vice-President of Karolinska Institutet on 1 January 2016. On 18 February that same year, the government appointed me Karolinska Institutet’s acting President, a position I relinquished on 1 August 2017 to resume my previous title. I left my position as Vice President 9 September 2019. From 2009 until August 2015 I was head of the Department of Biosciences and Nutrition, and in 2015 I was vice-dean of infrastructure.
Between September 2013 and June 2015 I was KI Scientific Director at SciLifeLab with special responsibility for the national platforms, and was a member of SciLifeLab’s operational management. In 2001 I founded BEA, a core facility that provides advanced services in genomics and bioinformatics. From 1994 to 2000 I held the positions of line manager and project manager at Pharmacia and Upjohn. I am also active in the Strategic Research Area in Diabetes at KI.
Commission of trust
I am a member of the SciLifeLab Stockholm steering board and the joint steering committee for AstraZeneca/KI/ SciLifeLab collaboration. I am also a member of the reference group for the European spallation resource ESS I have acted as Chairman, vice Chairman and member of evaluation panels at the Swedish Research Council. I have evaluated research in Norway on request of the Norwegian Research Council. 2007-2008 and 2015-, I was a member of the KI-SLL infrastructure council. I have taken part in a committee on behalf of the Swedish department of justice with regard to patents in the area of biotechnology and I am appointed expert in patent cases.
Education
Ph.D Medical Sciences, Karolinska Institutet, 1991
Docent Molecular Endocrinology, Karolinska Institutet, 1996
Research
- My research is focused on studies of estrogen signaling with specific focus on type 2 diabetes and breast cancer. We study phenotypes of mouse models with tissue selective knock-out of estrogen receptors and relate this to molecular changes such as changes in global gene expression. We use different breast cancer cell models and functional genomics technologies, such as ChIP SEQ, global gene expression analysis and proteomics, to identify signaling pathways that can include possible targets for treatment of breast cancer.
Articles
- Article: ONCOGENE. 2018;37(19):2586-2600
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2018;103(2):710-721
- Article: ONCOTARGET. 2017;8(44):76622-76633
- Article: SCIENTIFIC REPORTS. 2017;7(1):10152
- Article: ACTA PHYSIOLOGICA. 2017;219(2):486-493
- Article: ONCOTARGET. 2016;7(44):71580-71593
- Article: CANCER RESEARCH. 2016;76(19):5634-5646
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(29):15169-15184
- Article: ONCOGENE. 2016;35(15):1955-1964
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(10):5068-5079
- Article: MOLECULAR BIOLOGY REPORTS. 2016;43(3):141-150
- Article: MOLECULAR METABOLISM. 2016;5(3):171-183
- Article: PLOS ONE. 2016;11(10):e0164241
- Article: OBESITY. 2016;24(1):250-261
- Article: ONCOTARGET. 2015;6(41):43853-43868
- Article: MOLECULAR METABOLISM. 2015;4(12):891-902
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;466(4):650-655
- Article: ONCOTARGET. 2015;6(32):33623-33635
- Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2015;29(4):557-568
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2015;39(6):910-919
- Article: ONCOTARGET. 2015;6(10):7804-7814
- Article: CLINICAL EPIGENETICS. 2015;7(1):93
- Article: ONCOGENE. 2014;33(34):4340-4351
- Article: CANCER RESEARCH. 2014;74(14):3983-3994
- Article: CELL METABOLISM. 2014;19(6):981-992
- Article: BREAST CANCER RESEARCH. 2014;16(1):R21
- Article: PLOS ONE. 2014;9(1):e85581
- Article: BMC CANCER. 2013;13:441
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(6):2294-2299
- Article: PLOS ONE. 2013;8(2):e57458
- Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2012;49(3):277-287
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;426(1):26-32
- Article: CARCINOGENESIS. 2012;33(9):1684-1691
- Article: DIABETES. 2012;61(8):1986-1993
- Article: SHOCK. 2012;37(4):355-359
- Article: GENOME BIOLOGY. 2012;13(3):R24
- Article: NEUROTOXICOLOGY AND TERATOLOGY. 2011;33(6):752-764
- Article: JOURNAL OF ALZHEIMER'S DISEASE. 2011;26(3):431-439
- Article: BMC MEDICAL GENOMICS. 2011;4:51
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(6):E962-E966
- Article: PLOS ONE. 2010;5(12):e15594
- Article: CURRENT OPINION IN PHARMACOLOGY. 2010;10(6):692-697
- Article: PLOS ONE. 2010;5(11):e14085
- Article: CANCER RESEARCH. 2010;70(12):5174-5183
- Article: BRITISH JOURNAL OF CANCER. 2010;102(10):1541-1548
- Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(4):471-478
- Article: CANCER RESEARCH. 2010;70(3):1265-1274
- Article: ENDOCRINE. 2009;36(2):224-232
- Article: BMC GENETICS. 2009;10:55
- Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2009;43(1-2):65-72
- Article: PLOS ONE. 2009;4(6):e5805
- Article: BMC MEDICAL GENETICS. 2009;10:27
- Article: JOURNAL OF ENDOCRINOLOGY. 2008;199(2):275-286
- Article: PHARMACOGENETICS AND GENOMICS. 2008;18(11):967-975
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2008;295(4):E904-E912
- Article: FERTILITY AND STERILITY. 2008;90(1):44-48
- Article: JOURNAL OF ENDOCRINOLOGY. 2008;196(3):547-557
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(7):2604-2609
- Article: MOLECULAR ENDOCRINOLOGY. 2008;22(1):10-22
- Article: PLOS ONE. 2008;3(10):e3519
- Article: BMC MEDICAL GENETICS. 2007;8:73
- Article: FERTILITY AND STERILITY. 2007;88(1):100-106
- Article: INTERNATIONAL JOURNAL OF OBESITY. 2007;31(6):900-907
- Article: CANCER RESEARCH. 2007;67(8):3955-3962
- Article: JOURNAL OF CLINICAL PATHOLOGY. 2007;60(2):195-198
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2007;35(14):4858-4868
- Article: PHARMACOGENETICS AND GENOMICS. 2006;16(12):881-889
- Article: INFLAMMATION RESEARCH. 2006;55(8):349-353
- Article: CLIMACTERIC. 2006;9(3):215-223
- Article: PHARMACOGENETICS AND GENOMICS. 2006;16(5):379-383
- Article: CLINICAL CANCER RESEARCH. 2006;12(6):1936-1941
- Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2006;83(3):592-600
- Article: DIABETOLOGIA. 2006;49(3):588-597
- Article: DISEASES OF THE ESOPHAGUS. 2006;19(1):20-23
- Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2005;82(6):1260-1268
- Article: JOURNAL OF MEDICAL GENETICS. 2005;42(11):847-851
- Article: JOURNAL OF PATHOLOGY. 2005;207(1):91-101
- Article: BIOCHEMISTRY. 2005;44(22):7936-7944
- Article: EXPERIMENTAL ONCOLOGY. 2005;27(2):102-107
- Article: MOLECULAR PHARMACOLOGY. 2005;67(3):815-826
- Article: MOLECULAR ENDOCRINOLOGY. 2005;19(3):632-643
- Article: ENDOCRINOLOGY. 2004;145(12):5525-5531
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;287(6):E1125-E1131
- Article: CARCINOGENESIS. 2004;25(11):2067-2073
- Article: HUMAN MOLECULAR GENETICS. 2004;13(15):1551-1561
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2004;151(2):259-263
- Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2004;32(3):879-892
- Article: PROTEIN EXPRESSION AND PURIFICATION. 2004;35(2):190-198
- Article: MOLECULAR PSYCHIATRY. 2004;9(1):28-34
- Article: ONCOGENE. 2003;22(48):7600-7606
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;310(2):589-593
- Article: MOLECULAR ENDOCRINOLOGY. 2003;17(9):1844-1855
- Article: ENDOCRINOLOGY. 2003;144(8):3541-3546
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2003;79(3):409-413
- Article: MOLECULAR ENDOCRINOLOGY. 2003;17(2):203-208
- Article: NUCLEAR RECEPTOR SIGNALING. 2003;1:e003-nrs.01003
- Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2002;17(12):2183-2195
- Article: MOLECULAR PHARMACOLOGY. 2002;62(6):1299-1305
- Article: JOURNAL OF ENDOCRINOLOGY. 2002;174(2):167-178
- Article: BIOCHEMISTRY. 2001;40(20):5861-5869
- Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 1999;22(3):313-325
- Article: MOLECULAR PHARMACOLOGY. 1995;48(5):938-945
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All other publications
- Corrigendum: ONCOGENE. 2019;38(2):299-300
- Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2014;382(1):665-672
- Review: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION. 2013;15(3):81-90
- Review: JOURNAL OF ENDOCRINOLOGY. 2012;212(1):3-12
- Review: CURRENT OPINION IN ONCOLOGY. 2012;24(1):58-61
- Published conference paper: DIABETES/METABOLISM RESEARCH AND REVIEWS. 2011;27(7):697-704
- Editorial comment: EMBO JOURNAL. 2011;30(13):2516-2517
- Review: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2011;334(1-2):83-90
- Review: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(51):39575-39579
- Review: JOURNAL OF ENDOCRINOLOGY. 2010;204(3):233-240
- Review: NUCLEAR RECEPTOR SIGNALING. 2008;6:e003
- Review: PHARMACOLOGICAL REVIEWS. 2006;58(4):773-781
- Review: ESSAYS IN BIOCHEMISTRY. 2004;40:157-167
- Letter: JOURNAL OF BIOMOLECULAR NMR. 2000;17(2):181-182
Employments
- Specialist, Central Administration, Karolinska Institutet, 2024-
Degrees and Education
- Docent, Karolinska Institutet, 1996