Kaarina Kowalec

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2024;11(6):1393-1404

Polygenic liability for anxiety in association with comorbid anxiety in multiple sclerosis.

Kowalec K; Harder A; Dolovich C; Fitzgerald KC; Salter A; Lu Y; Bernstein CN; Bolton JM; Cutter G; Fisk JD; Gelernter J; Graff LA; Hägg S; Hitchon CA; Levey DF; Lublin FD; McKay KA; Patten S; Patki A; Stein MB; Tiwari HK; Wolinsky JS; Marrie RA
Article: NEUROLOGY. 2024;102(5):e209135

Investigating the Prevalence of Comorbidity in Multiple Sclerosis Clinical Trial Populations.

Salter A; Lancia S; Kowalec K; Fitzgerald KC; Marrie RA
Article: PHARMACOGENOMICS. 2024;25(4):175-186

Knowledge and perceptions of pharmacogenomics among pharmacists in Manitoba, Canada.

Maruf AA; Shields M; Fryza A; Wondrasek A; Leong C; Kowalec K; Bousman C
Article: HEALTH SCIENCE REPORTS. 2024;7(1):e1844

Knowledge, perceptions, and attitudes toward pharmacogenomics among pharmacists and pharmacy students: A systematic review.

Wondrasek A; Fryza A; Aziz MA; Leong C; Kowalec K; Maruf AA
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722

Genetic Contribution to the Heterogeneity of Major Depressive Disorder: Evidence From a Sibling-Based Design Using Swedish National Registers.

Nguyen T-D; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):301

Polygenic risk scores of lithium response and treatment resistance in major depressive disorder.

Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigström R; Jonsson L; Clements CC; Andersson E; Boberg J; Lewis CM; Sullivan PF; Landén M; Lu Y
Article: JOURNAL OF PSYCHOSOMATIC RESEARCH. 2023;172:111415

Assessment of differential item functioning of the PHQ-9, HADS-D and PROMIS-depression scales in persons with and without multiple sclerosis.

Marrie RA; Lix LM; Bolton JM; Fisk JD; Fitzgerald KC; Graff LA; Hitchon CA; Kowalec K; Marriott JJ; Patten SB; Salter A; Bernstein CN; CIHR Team in Defining the Burden and Managing the
Article: NEUROLOGY. 2023;101(5):e522-e532

Polygenicity of Comorbid Depression in Multiple Sclerosis.

Kowalec K; Fitzgerald KC; Salter A; Dolovich C; Harder A; Bernstein CN; Bolton J; Cutter GR; Graff LA; Hägg S; Hitchon CA; Lu Y; Lublin F; McKay KA; Patten SB; Patki A; Tiwari HK; Wolinsky JS; Marrie RA
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2023;43(4):313-319

Adherence to Psychotropic Medication Before and During COVID-19: A Population-Wide Retrospective Observational Study.

Froese B; Aquino G; Valencia E; Tan Q; Yogendran M; Katz C; Bolton JM; Falk J; Kowalec K; Chateau D; Delaney JC; Logsetty S; Spiwak R; Enns MW; Sareen J; Alessi-Severini S; Olafson K; Eltonsy S; Leong C
Journal article: BMJ OPEN. 2023;13(6):e073782

Well-being and flourishing mental health in adults with inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis in Manitoba, Canada: a cross-sectional study.

Almweisheer S; Bernstein CN; Graff LA; Patten SB; Bolton J; Fisk JD; Hitchon CA; Marriott JJ; Marrie RA; CIHR Team in Defining the Burden and Managing the
Article: THE LANCET REGIONAL HEALTH - EUROPE. 2023;29:100621

Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers.

Pasman JA; Meijsen JJ; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lu Y
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2023;45(1):233-239

Sex differences among users of NSAIDs and opioids during COVID-19 Pandemic.

Offiah R; Aboulatta L; Peymani P; Aloud B; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
Article: BMJ PAEDIATRICS OPEN. 2023;7(1):e001686

Preterm birth and stillbirth rates associated with socioeconomic disparities during COVID-19 pandemic: a population-based cross-sectional study.

Aboulatta L; Kowalec K; Leong C; Delaney JA; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Vaccaro C; Lavu A; Haidar L; Peymani P; Eltonsy S
Article: NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2023;10(1):e200062

Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple Sclerosis.

Vasileiou ES; Hu C; Bernstein CN; Lublin F; Wolinsky JS; Cutter GR; Sotirchos ES; Kowalec K; Salter A; Saidha S; Mowry EM; Calabresi PA; Marrie RA; Fitzgerald KC
Article: FRONTIERS IN PSYCHIATRY. 2023;14:1260420

Sex differences evident in elevated anxiety symptoms in multiple sclerosis, inflammatory bowel disease, and rheumatoid arthritis.

Joyees J; Marrie RA; Bernstein CN; Bolton JM; Fisk JD; Graff LA; Hitchon C; Patten SB; Kowalec K; CIHR team in defining the burden and managing the
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(11):844-852

Association Between Polygenic Risk Scores and Outcome of ECT.

Sigström R; Kowalec K; Jonsson L; Clements CC; Karlsson R; Nordenskjöld A; Pålsson E; Sullivan PF; Landén M
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e31-e32

TRYGGVE2: SECURE & PRECISE GENETIC ANALYSES IN THE NORDIC COUNTRIES AND BEYOND

Lu Y; Kowalec K; Werge T; Andreassen O; Sullivan P
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e270

INVESTIGATING GENETIC OVERLAP BETWEEN ANTIDEPRESSANTS AND LITHIUM RESPONSE AND TREATMENT RESISTANCE IN MAJOR DEPRESSIVE DISORDER

Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M; Lu Y
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e198

T55. POLYGENICITY OF COMORBID DEPRESSION IN MULTIPLE SCLEROSIS

Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hägg S; Hitchon C; Bernstein CN; Cutter G; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e32-e33

NEXT GENERATION GENOME-WIDE ASSOCIATION STUDY OF SCHIZOPHRENIA FROM SWEDEN

Kowalec K; Karlsson R; Lu Y; Song J; Yao S; Szatkiewicz J; Kähler A; Schalling M; Österholm A-M; Hultman C; Lavebratt C; Landen M; Karlsson H; Dalman C; Sullivan P
Article: GENERAL HOSPITAL PSYCHIATRY. 2022;77:21-28

Depressive symptom trajectories and polygenic risk scores in individuals with an immune-mediated inflammatory disease.

Kowalec K; Salter A; Fitzgerald KC; Patel M; Han J; Lu Y; Bolton JM; Hitchon C; Bernstein CN; Patten S; Graff LA; Marriott JJ; Marrie RA; CIHR Team in Defining the Burden and Managing the
Article: BMC RESEARCH NOTES. 2022;15(1):162

Trends of COVID-19 incidence in Manitoba and public health measures: March 2020 to February 2022.

Aboulatta L; Kowalec K; Delaney J; Alessi-Severini S; Leong C; Falk J; Eltonsy S
Article: MOLECULAR PSYCHIATRY. 2022;27(5):2439-2447

The impact of educational attainment, intelligence and intellectual disability on schizophrenia: a Swedish population-based register and genetic study.

Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz JP; Larsson H; Lichtenstein P; Hultman CM; Sullivan PF
Article: MOLECULAR PSYCHIATRY. 2022;27(3):1667-1675

Genetic heterogeneity and subtypes of major depression.

Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan PF; Lu Y
Article: JAMA PSYCHIATRY. 2022;79(3):260-269

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.

Pardiñas AF; Smart SE; Willcocks IR; Holmans PA; Dennison CA; Lynham AJ; Legge SE; Baune BT; Bigdeli TB; Cairns MJ; Corvin A; Fanous AH; Frank J; Kelly B; McQuillin A; Melle I; Mortensen PB; Mowry BJ; Pato CN; Periyasamy S; Rietschel M; Rujescu D; Simonsen C; St Clair D; Tooney P; Wu JQ; Andreassen OA; Kowalec K; Sullivan PF; Murray RM; Owen MJ; MacCabe JH; O'Donovan MC; Walters JTR; Genetics Workstream of the Schizophrenia Treatment; Ajnakina O; Alameda L; Barnes TRE; Berardi D; Bonora E; Camporesi S; Cleusix M; Conus P; Crespo-Facorro B; D'Andrea G; Demjaha A; Do KQ; Doody GA; Eap CB; Ferchiou A; Di Forti M; Guidi L; Homman L; Jenni R; Joyce EM; Kassoumeri L; Khadimallah I; Lastrina O; Muratori R; Noyan H; O'Neill FA; Pignon B; Restellini R; Richard J-R; Schürhoff F; Španiel F; Szöke A; Tarricone I; Tortelli A; Üçok A; Vázquez-Bourgon J
Article: PLOS ONE. 2022;17(11):e0278072

Drug utilization patterns before and during COVID-19 pandemic in Manitoba, Canada: A population-based study.

Aboulatta L; Peymani P; Vaccaro C; Leong C; Kowalec K; Delaney J; Falk J; Alessi-Severini S; Aloud B; Eltonsy S
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:886652

Psychotropic Medication Use Before and During COVID-19: A Population-Wide Study.

Leong C; Kowalec K; Eltonsy S; Bolton JM; Enns MW; Tan Q; Yogendran M; Chateau D; Delaney JA; Sareen J; Falk J; Spiwak R; Logsetty S; Alessi-Severini S
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:871136

Trends of Utilization of Antiseizure Medications Among Pregnant Women in Manitoba, Canada: A 20-Year Population-Based Study.

Shouman W; Delaney JA; Kowalec K; Ng M; Ruth C; Falk J; Leong C; Alessi-Severini S; Lavu A; Peymani P; Eltonsy S
Article: ACR OPEN RHEUMATOLOGY. 2021;3(12):889-896

Prevalence and Risk Factors of Substance Use Disorder in Rheumatoid Arthritis.

Kowalec K; Carney H; Patel M; Hitchon C; Bolton JM; Patten SB; Graff LA; Bernstein CN; Peschken C; Marrie RA; Canadian Institutes of Health Research Team in Def
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(13):2077-2084

Mendelian randomization provides no evidence for a causal role in the bidirectional relationship between depression and multiple sclerosis.

Harroud A; Marrie RA; Fitzgerald KC; Salter A; Lu Y; Patel M; Kowalec K
Article: MOLECULAR PSYCHIATRY. 2021;26(8):4487-4495

Increased schizophrenia family history burden and reduced premorbid IQ in treatment-resistant schizophrenia: a Swedish National Register and Genomic Study.

Kowalec K; Lu Y; Sariaslan A; Song J; Ploner A; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):163

The association between family history and genomic burden with schizophrenia mortality: a Swedish population-based register and genetic sample study.

Kowalec K; Lu Y; Song J; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
Article: ELIFE. 2021;10:e58430

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia.

Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forti M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard CJ; Nenadic I; O'Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Wellcome Trust Case Control Consortium (WTCCC); CRESTAR consortium; Sullivan P; Vassos E; Breen G; Collier DA; Murray RM; Schalkwyk LS; Mill J
Article: INFLAMMATORY BOWEL DISEASES. 2021;27(1):58-64

Prevalence and Risk Factors of Substance Use Disorder in Inflammatory Bowel Disease.

Carney H; Marrie RA; Bolton JM; Patten SB; Graff LA; Bernstein CN; Kowalec K
Article: NEUROLOGY. 2020;95(5):e446-e456

Comorbidity is associated with disease activity in MS: Findings from the CombiRx trial.

Salter A; Kowalec K; Fitzgerald KC; Cutter G; Marrie RA
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s236

T36UNDERSTANDING PSYCHIATRIC COMORBIDITY IN CHRONIC IMMUNOINFLAMMATORY DISEASES USING GENOMICS

Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):157

Methylation age acceleration does not predict mortality in schizophrenia.

Kowalec K; Hannon E; Mansell G; Burrage J; Ori APS; Ophoff RA; Mill J; Sullivan PF
Article: NATURE GENETICS. 2018;50(8):1081-1085

Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis.

Kowalec K; Wright GEB; Drögemöller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager PL; Denny JC; Davis MF; Ross CJD; Tremlett H; Carleton BC
Article: NEUROLOGY. 2018;90(4):e332-e341

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.

McCormack M; Gui H; Ingason A; Speed D; Wright GEB; Zhang EJ; Secolin R; Yasuda C; Kwok M; Wolking S; Becker F; Rau S; Avbersek A; Heggeli K; Leu C; Depondt C; Sills GJ; Marson AG; Auce P; Brodie MJ; Francis B; Johnson MR; Koeleman BPC; Striano P; Coppola A; Zara F; Kunz WS; Sander JW; Lerche H; Klein KM; Weckhuysen S; Krenn M; Gudmundsson LJ; Stefánsson K; Krause R; Shear N; Ross CJD; Delanty N; EPIGEN Consortium; ; Pirmohamed M; Carleton BC; Canadian Pharmacogenomics Network for Drug Safety; ; Cendes F; Lopes-Cendes I; Liao W-P; O'Brien TJ; Sisodiya SM; EpiPGX Consortium; ; Cherny S; Kwan P; Baum L; International League Against Epilepsy Consortium o; Cavalleri GL
Article: NEUROLOGY. 2017;89(24):2455-2461

Comorbidity increases the risk of relapse in multiple sclerosis: A prospective study.

Kowalec K; McKay KA; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA; CIHR Team in Epidemiology and Impact of Comorbidit
Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:173

Genome-wide Scan Identifies Association Between an Interferon Regulatory Factor Variant and Interferon-beta Induced Liver Injury in Multiple Sclerosis Patients

Kowalec K; Wright GEB; Drögemöller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager P; Ross C; Tremlett H; Carleton B
Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:167

Pharmacogenomic Prediction of Ribavirin-Induced Hemolytic Anemia in Patients Treated for Hepatitis C Infection

Abel S; Aminkeng F; Kowalec K; Drogemoller B; Wright G; Bader R; Stortz J; Yoshida E; Lee S; Al-Judaibi B; Kim R; Tam E; Ramji A; Ross C; Carleton B
Article: BMJ OPEN. 2017;7(5):e016276

Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case-control study protocol for dimethyl fumarate-induced lymphopenia.

Kowalec K; Kingwell E; Carruthers R; Marrie RA; Bernatsky S; Traboulsee A; Ross CJD; Carleton B; Tremlett H
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2016;85(3):328-333

Discordant diagnostic results due to a hepatitis B virus T123A HBsAg mutant.

Osiowy C; Kowalec K; Giles E
Article: NATURE GENETICS. 2015;47(9):1079-1084

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer.

Aminkeng F; Bhavsar AP; Visscher H; Rassekh SR; Li Y; Lee JW; Brunham LR; Caron HN; van Dalen EC; Kremer LC; van der Pal HJ; Amstutz U; Rieder MJ; Bernstein D; Carleton BC; Hayden MR; Ross CJD; Canadian Pharmacogenomics Network for Drug Safety
Article: JOURNAL OF VIRAL HEPATITIS. 2013;20(2):122-130

Genetic diversity of hepatitis B virus genotypes B6, D and F among circumpolar indigenous individuals.

Kowalec K; Minuk GY; Børresen ML; Koch A; McMahon BJ; Simons B; Osiowy C
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(1):57-59

Suspected autoimmune hepatitis and primary biliary cirrhosis unmasked by interferon-beta in a multiple sclerosis patient.

Kowalec K; Yoshida EM; Traboulsee A; Carleton B; Tremlett H
Article: JOURNAL OF MEDICAL VIROLOGY. 2012;84(9):1369-1375

The prevalence and long term outcome of occult hepatitis B virus infections in community based populations.

Minuk GY; Kowalec K; Caouette S; Larke B; Osiowy C
Article: JOURNAL OF MEDICAL VIROLOGY. 2010;82(6):942-948

Molecular characterization of hepatitis B virus and a 9-year clinical profile in a patient infected with genotype I.

Osiowy C; Kaita K; Solar K; Mendoza K
Visa fler

Alla övriga publikationer

Preprint: MEDRXIV. 2023

Subtyping Schizophrenia Using Psychiatric Polygenic Scores

Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Giusti-Rodríguez P; Sullivan PF; Yao S
Preprint: RES SQ. 2023;RES SQ

Investigating genetic overlap between antidepressant and lithium response and treatment resistance in major depressive disorder.

Lu Y; Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigstrom R; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M
Review: FRONTIERS IN IMMUNOLOGY. 2023;14:1197195

Etiology, effects and management of comorbidities in multiple sclerosis: recent advances.

Marrie RA; Fisk JD; Fitzgerald K; Kowalec K; Maxwell C; Rotstein D; Salter A; Tremlett H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E159

POLYGENIC RISK AND BODY MASS INDEX IN THE SWE-DEN SCHIZOPHRENIA STUDY

Kowalec K; Song J; Yao S; Karlsson R; Lu Y; Bergen S; Harder A; Kahler A; Osterholm A-M; Hultman C; Sullivan P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50

GENETIC EPIDEMIOLOGY AND POLYGENICITY OF PSYCHOTIC MAJOR DEPRESSIVE DISORDER

Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y
Preprint: MEDRXIV. 2022

COVID-19 pandemic impact on preterm birth and stillbirth rates associated with socioeconomic disparities: A quasi-experimental study

Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Lavu A; Haidar L; Vaccaro C; Eltonsy S
Review: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;111(4):919-930

A Systematic Review and Analysis of the Use of Polygenic Scores in Pharmacogenomics.

Johnson D; Wilke MAP; Lyle SM; Kowalec K; Jorgensen A; Wright GEB; Drögemöller BI
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(1_SUPPL):52

Biostatistical Methods

Hu C; Marrie RA; Salter A; Kowalec K; Fitzgerald K
Conference publication: BIRTH DEFECTS RESEARCH. 2022;114(9):395

Impact of COVID-19 Pandemic on Preterm Birth and Stillbirth Rates in Manitoba, Canada: A Quasi-Experimental Study

Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):212

Polygenicity of comorbid depression in multiple sclerosis

Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hagg S; Hitchon C; Bernstein CN; Cutter G; Marriott JJ; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
Review: PSYCHOLOGICAL MEDICINE. 2021;51(13):2168-2177

Genetic architecture of schizophrenia: a review of major advancements.

Legge SE; Santoro ML; Periyasamy S; Okewole A; Arsalan A; Kowalec K
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E137-E138

THE IMPACT OF EDUCATIONAL ATTAINMENT, IN-TELLIGENCE AND INTELLECTUAL DISABILITY ON SCHIZOPHRENIA: A SWEDISH POPULATION-BASED REGISTER AND GENETIC STUDY

Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz J; Larsson H; Lichtenstein P; Hultman C; Sullivan P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E237

CLUSTERING OF SCHIZOPHRENIA CASES BASED ON COMMON GENETIC VARIANTS

Yao S; Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Sullivan P
Preprint: MEDRXIV. 2021

Genetic heterogeneity and subtypes of major depression

Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan P; Lu Y
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(1_SUPPL):58-59

Mendelian Randomization Provides No Evidence for a Causal Role in the Bidirectional Relationship Between Depression and Multiple Sclerosis

Harroud A; Marrie R; Richards B; Fitzgerald K; Salter A; Lu Y; Patel M; Kowalec K
Preprint: BIORXIV. 2020

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia

Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forta M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard C; Nenadic I; O’Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Consortium WTCC; consortium CA; Sullivan P; Vassos E; Breen G; Collier DA; Murray R; Schalkwyk LS; Mill J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S85-S86

TRYGGVE2: PREDICTING POOR OUTCOMES IN SCHIZOPHRENIA USING REGISTER GENOMICS IN SWEDEN

Kowalec K; Yi L; Drange OK; Weinsheimer S; Tesli M; Folkersen L; Werge T; Andreassen OA; Reichborn-Kjennerud T; Sullivan P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S215

INCREASED SCHIZOPHRENIA FAMILY HISTORY BURDEN AND REDUCED PREMORBID IQ IN TREATMENT-RESISTANT SCHIZOPHRENIA: A SWEDISH NATIONAL REGISTER AND GENOMIC STUDY

Kowalec K; Yi L; Sariaslan A; Song J; Ploner A; Dalman C; Hultman C; Larsson H; Lichtenstein P; Sullivan P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s183-s184

TRYGGVE2: PREDICTING POOR OUTCOMES IN MAJOR DEPRESSION USING REGISTER GENOMICS IN SWEDEN

Lu Y; Kowalec K; Drange OK; Tesli M; Weinsheimer S; Folkersen L; Werge T; Andreassen O; Reichborn-Kjennerud T; Sullivan P
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:648

Understanding psychiatric comorbidity in multiple sclerosis using genomics

Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1099-1100

METHYLOMIC BIOMARKERS OF SCHIZOPHRENIA AND ANTIPSYCHOTIC MEDICATION EXPOSURE

Hannon E; Dempster E; Mansell G; Schalkwyk L; Murray R; McQuillin A; Kowalec K; St Clair D; Morris D; Sullivan P; O'Donovan M; MacCabe J; Collier D; Mill J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1332-1333

PREDICTION OF MORTALITY USING DNA METHYLATION AGE IN SCHIZOPHRENIA

Kowalec K; Hannon E; Mansell G; Burrage J; Mill J; Sullivan P
Editorial comment: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2017;12:1-3

From bugs to brains: The microbiome in neurological health.

McKay KA; Kowalec K; Brinkman F; Finlay BB; Horwitz M; Manges AR; Osborne L; Tremlett H
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2017;23:991

Comorbidity increases the risk of relapse in multiple sclerosis: a prospective study

Kowalec K; McKay K; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA
Review: EXPERT OPINION ON DRUG SAFETY. 2014;13(10):1305-1317

Characteristics associated with drug-induced liver injury from interferon beta in multiple sclerosis patients.

Kowalec K; Kingwell E; Yoshida EM; Marrie RA; Kremenchutzky M; Campbell TL; Wadelius M; Carleton B; Tremlett H
Review: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(3):183-192

The potential role of pharmacogenomics in the prevention of serious adverse drug reactions in multiple sclerosis.

Kowalec K; Carleton B; Tremlett H
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Forskningsbidrag

Capitalising on our differences: A gathering to better understand and advocate for Early Career Health Researchers in Canada

Canadian Institutes of Health Research

1 January 2023 - 31 December 2023
Precision Genomics Suite

Canada Foundation for Innovation

22 November 2022
Psychiatric Disorder Genomic Risk Scores as a Correlate of Disease Activity and Progression in Multiple Sclerosis

Congressionally Directed Medical Research Programs

15 July 2020 - 14 July 2024
Enhancing CAN-AIM capacity to respond to drug safety and effectiveness queries

Canadian Institutes of Health Research

1 September 2019 - 31 August 2022
Identifying Clinical, Demographic, & Genomic Risk Factors for Treatment-Resistant Psychiatric Disorders

Canadian Institutes of Health Research

1 April 2018 - 3 January 2019
The Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT) Program

Canadian Institutes of Health Research

1 November 2015 - 28 February 2022
Genotype specific approaches to beta-interferon therapy in Multiple Sclerosis

Canadian Institutes of Health Research

1 May 2011 - 31 October 2014

Anställningar

Assistant Professor, Genetics, University of Manitoba, 2019-
Anknuten till Forskning, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2022-2025

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PhD, Genetics and epidemiology, University of British Columbia, 2016
MSc, Viral genetics, University of Manitoba, 2011
BSc, Microbiology, University of Manitoba, 2008

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