Kaarina Kowalec
About me
I am a tenured Associate Professor at the Rady Faculty of Health Sciences at University of Manitoba and hold an Affiliated Research
position at the Karolinska Institutet. My research aims to identify precision medicine approaches to neurological diseases and psychiatric disorders by combining genomics, biostatistics, and epidemiology, to advance the outcomes of those affected by neurological and psychiatric disorders. Our work regularly involves an extensive network of Canadian, American, Swedish, and other International collaborators. I am funded by the US Department of Defense, US NIMH and the Consortium of Multiple Sclerosis Centres. We are a "dry-lab" focussed on computation and analysis, but collaborate with "wet-lab" groups internationally.
During my postdoctoral and PhD studies, I held fellowships from the European Commission (Horizon-2020), and the Canadian Institutes of Health Research (CIHR), including the Marie Skłodowska-Curie Actions-Horizon 2020 European Fellowship (€180K) and the Government of Canada Banting Fellowship, with over 20 awards during my PhD alone, totalling over $960K in personal salary awards, and $1.8M in peer-reviewed operating and team grants. From 2017-19, I was a Postdoctoral researcher at the Karolinska Institute with Professor Patrick Sullivan and the KI-Psychiatric Genomics Institute to harness my collaborative, problem-solving abilities that I have developed during my doctoral training and apply them to the intricate issues faced today by the psychiatric community. My projects involved utilizing the Swedish National Register data, the Sweden Schizophrenia Study, and other psychiatric cohort studies.
Research
- Theme 1: Epidemiology and genomics of poor outcomes in schizophrenia
Schizophrenia (SCZ) is one of the top 15 leading causes of disability worldwide, with the average number of life years lost ~30 years. Those with SCZ are at 15-25 times higher risk for suicide, compared to the general population. It is currently estimated that ~200, 000 Canadians have SCZ. In 2004, the direct healthcare and non-healthcare costs related to SCZ in Canada were estimated at >$2B, and when considering additional losses, resulted in a total cost estimate of $6.85B. Features associated with poor outcomes in SCZ include childhood adversities (e.g. neglect), family history of psychiatric disorders, and SCZ genomic burden (the weighted sum of the number of SCZ genetic risk variants within each individual). There are currently no means of predicting, at first clinical presentation, who will experience a poor outcome in SCZ. Our overall goal is early detection of those at high risk for poor outcomes in SCZ, thereby triggering logical and effective interventions to mitigate the personal, social, and societal costs associated with severe SCZ. Our overarching translational goal is to develop valid and clinically useful models that predict crucial clinical outcomes for psychiatry and to implement the predictive models on a provincial and national scale.
Projects:- Investigating the association between accelerated DNA methylation age and mortality in SCZ. This work is published in Translational Psychiatry.
- Using population-based Swedish National register data and extensive genomic data to examine treatment resistance in schizophrenia (published in Molecular Psychiatry).
- Investigating the role of genetic variation in association with specific and all cause mortality in schizophrenia. This work is published in Translation Psychiatry.
Theme 2: Epidemiology and genomics of poor outcomes in multiple sclerosis (MS) and other chronic immunoinflammatory diseases
The prevention of poor outcomes, such as serious adverse drug reactions associated with MS therapies or the development of psychiatric disorders, is essential for those with MS and other chronic immunoinflammatory diseases. Currently, there are few clinically useful predictors of poor outcomes in MS. Variability in the genes that underscore drug biotransformation may be the key to identifying and predicting who is at greatest risk of serious adverse drug reactions and likewise, investigating the genes that underlie polygenic traits like psychiatric disorders, may also be important in investigating those at greatest risk for a psychiatric disorder. Findings from our cutting-edge work (published in Nature Genetics, Neurology, BMJ Open, Expert Opinion in Drug Safety, and MS and Related Disorders) could improve outcomes in MS and contribute to the future development of precision medicine approaches to MS and other autoimmune diseases.
Projects:- Understanding psychiatric comorbidity in chronic immunoinflammatory diseases using genomics: We published work modelling longitudinal depressive symptoms in IMID to understand their evolution and identify any associated factors (including polygenic risk scores), with the overall goal of identifying those at highest risk of higher depressive symptom burden. This work is published in General Hospital Psychiatry. We then followed this with an assessment of depression polygenicity in multiple sclerosis and this work is published in Neurology and an assessment of anxiety polygenicity in MS, published in ACTN. We also aimed to better understand the bidirectional relationship between multiple sclerosis and depression using Mendelian randomization and found no evidence for a causal role for this relationship. This was published in MSJ.
- Understanding factors associated with substance use disorder in those with inflammatory bowel disease and rheumatoid arthritis in Manitoba. These projects are now published in Inflammatory Bowel Diseases and ACR Open.
- Genomic variants associated with DMF induced lymphopenia in MS [GenDMF-MS]: Seeking to predict and ultimately prevent adverse drug reactions in people with MS. An international pharmacogenomic investigation of lymphopenia due to dimethyl fumarate in multiple sclerosis, funded by the National MS Society. The protocol for this work can be found here and the project is in the analysis stage.
Teaching
2025
- Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed 60 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
2024
- Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed ~50 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
- Lecturer, College of Pharmacy, University of Manitoba PHMD2004: Instructed ~50 students in Critical Appraisal Pharmacotherapy Literature 1 (One 3-hour lecture)
- Mentor, College of Pharmacy, University of Manitoba PHMD4000: Instructed 6 fourth year PharmD students in a research project (12 weeks each).
2023
- Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed 35 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
- Lecturer, College of Pharmacy, University of Manitoba PHRM7102: Instructed 8 graduate students in Pharmacoepidemiology (One 3-hour lecture).
2022
- Course Coordinator, College of Pharmacy, University of Manitoba PHMD2012: Instructed 55 PharmD students in Pharmacogenetics (26 lectures of 60-minutes each).
- Mentor, College of Pharmacy, University of Manitoba PHMD4000: Instructed two fourth year PharmD students in a research project (12 weeks each).
2021
- Lecturer, College of Pharmacy, University of Manitoba PHMD2012: Planned the course syllabus and pre-recorded 10 lectures to be given as part of the Pharmacogenetics course (60-minutes each).
2020
- Lecturer, College of Pharmacy, University of Manitoba PHRM3640: Instructed 55 undergraduate Pharmacy students in Principles of Biotechnology (8 lectures of 75-minutes each).
2019
- Lecturer, College of Pharmacy, University of Manitoba PHRM4470: Current Topics in Pharmacy (1 hour)
- Lecturer, College of Pharmacy, University of Manitoba PHRM7260: Instructed 1 lecture of Pharmacy Graduate Student Seminar (1 hour)
- Lecturer, College of Pharmacy, University of Manitoba PHRM3520: Instructed 55 undergraduate Pharmacy students in Scientific Literature Evaluation (5 lectures of 90-minutes each).
- Lecturer, University of North Carolina-Chapel Hill and Karolinska Institutet: Instructed 20 researchers in R-Statistical Software tutoria
- Teaching and Learning Certificate, University of Manitoba: Two-year program designed to develop the knowledge, skills, and reflective practice.
2012-2016
- Teaching Assistant, Department of Biochemistry & Molecular Biology, Faculty of Science, UBC: Instructed undergraduate weekly laboratory session; monitored and assisted student biochemical and molecular biology experiments; evaluated student assignments, examinations, and progress; consistently rated highly amongst third-year undergraduate students.
2011-2012
- Laboratory Instructor, Biology Program, Faculty of Science, UBC: BIOL 140 Laboratory Investigations in Life Science: Instructed weekly laboratory sessions and preparatory sessions to enable students to participate in the scientific process; facilitated discussions with students and recorded student progress; assessed student work (assignments, written work, exams) and kept accurate records of student attendance, participation, and marks.
2008-2009
- Problem-Based Learning Facilitator, Rady College of Medicine, Department of Medical Microbiology, University of Manitoba
Articles
- Article: EBIOMEDICINE. 2025;112:105576Nguyen T-D; Meijsen JJ; Sigstroem R; Kuja-Halkola R; Xiong Y; Harder A; Kowalec K; Pasman JA; Scarpa C; Horbeck E; Jonsson L; Hagg S; Mullins N; O'Connell KS; Dalman C; Helenius D; Zetterberg R; Larsson H; Lichtenstein P; Andreassen OA; Werge T; Buil A; Landen M; Sullivan PF; Lu Y
- Article: JAMA PSYCHIATRY. 2024;81(12):1246-1252Song J; Pasman JA; Johansson V; Kuja-Halkola R; Harder A; Karlsson R; Lu Y; Kowalec K; Pedersen NL; Cannon TD; Hultman CM; Sullivan PF
- Article: FRONTIERS IN PHARMACOLOGY. 2024;15:1469552Peymani P; Berard A; Winquist B; Kaul P; Sheehy O; Lavu A; Leong C; Falk J; Delaney JA; Kowalec K; Ng M; Ruth C; Aboulatta L; Alessi-Severini S; Dragan R; Derksen S; Barrett O; Shams G; Eltonsy S
- Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2024;91:105866Hu C; Vasileiou ES; Salter A; Marrie RA; Kowalec K; Fitzgerald KC
- Article: SCHIZOPHRENIA RESEARCH. 2024;272:69-76Shirinbakhshmasoleh M; Aboulatta L; Leong C; Riel H; Liu K; Delaney JC; Bolton JM; Falk J; Alessi-Severini S; Eltonsy S; Kowalec K
- Article: JAMA NEUROLOGY. 2024;81(11):1170-1177Salter A; Lancia S; Kowalec K; Fitzgerald KC; Marrie RA
- Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2024;11(6):1393-1404Kowalec K; Harder A; Dolovich C; Fitzgerald KC; Salter A; Lu Y; Bernstein CN; Bolton JM; Cutter G; Fisk JD; Gelernter J; Graff LA; Haegg S; Hitchon CA; Levey DF; Lublin FD; Mckay KA; Patten S; Patki A; Stein MB; Tiwari HK; Wolinsky JS; Marrie RA
- Article: BMJ GLOBAL HEALTH. 2024;9(5):e015098Schindell BG; Fredborg B; Kowalec K; Shaw S; Kangbai JB; Kindrachuk J
- Journal article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2024;44(3):211Froese B; Aquino G; Valencia E; Tan Q; Yogendran M; Katz C; Bolton JM; Falk J; Kowalec K; Chateau D; Delaney JC; Logsetty S; Spiwak R; Enns MW; Sareen J; Alessi-Severini S; Olafson K; Eltonsy S; Leong C
- Article: NEUROLOGY. 2024;102(5):e209135Salter A; Lancia S; Kowalec K; Fitzgerald KC; Marrie RA
- Article: PHARMACOGENOMICS. 2024;25(4):175-186Al Maruf A; Shields M; Fryza A; Wondrasek A; Leong C; Kowalec K; Bousman C
- Article: HEALTH SCIENCE REPORTS. 2024;7(1):e1844Wondrasek A; Fryza A; Aziz MA; Leong C; Kowalec K; Al Maruf A
- Article: FRONTIERS IN PSYCHIATRY. 2023;14:1260420Joyees J; Marrie RA; Bernstein CN; Bolton JM; Fisk JD; Graff LA; Hitchon C; Patten SB; Kowalec K
- Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722Thuy-Dung N; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
- Article: TRANSLATIONAL PSYCHIATRY. 2023;13(1):301Xiong Y; Karlsson R; Song J; Kowalec K; Rueck C; Sigstroem R; Jonsson L; Clements CC; Andersson E; Boberg J; Lewis CM; Sullivan PF; Landen M; Lu Y
- Article: JOURNAL OF PSYCHOSOMATIC RESEARCH. 2023;172:111415Marrie RA; Lix LM; Bolton JM; Fisk JD; Fitzgerald KC; Graff LA; Hitchon CA; Kowalec K; Marriott JJ; Patten SB; Salter A; Bernstein CN
- Article: NEUROLOGY. 2023;101(5):e522-e532Kowalec K; Fitzgerald KC; Salter A; Dolovich C; Harder A; Bernstein CN; Bolton J; Cutter GR; Graff LA; Hagg S; Hitchon CA; Lu Y; Lublin F; McKay KA; Patten SB; Patki A; Tiwari HK; Wolinsky JS; Marrie RA
- Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2023;43(4):313-319Froese B; Aquino G; Valencia E; Tan Q; Yogendran M; Katz C; Bolton JM; Falk J; Kowalec K; Chateau D; Delaney JC; Logsetty S; Spiwak R; Enns MW; Sareen J; Alessi-Severini S; Olafson K; Eltonsy S; Leong C
- Journal article: BMJ OPEN. 2023;13(6):e073782Almweisheer S; Bernstein CN; Graff LA; Patten SB; Bolton J; Fisk JD; Hitchon CA; Marriott JJ; Marrie RA; CIHR Team in Defining the Burden and Managing the
- Article: LANCET REGIONAL HEALTH-EUROPE. 2023;29:100621Pasman JA; Meijsen J; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lua Y
- Article: BMJ PAEDIATRICS OPEN. 2023;7(1):e001686Aboulatta L; Kowalec K; Leong C; Delaney JA; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Vaccaro C; Lavu A; Haidar L; Peymani P; Eltonsy S
- Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2023;45(1):233-239Offiah R; Aboulatta L; Peymani P; Aloud B; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
- Article: NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2023;10(1):e200062Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple SclerosisVasileiou ES; Hu C; Bernstein CN; Lublin F; Wolinsky JS; Cutter GR; Sotirchos ES; Kowalec K; Salter A; Saidha S; Mowry EM; Calabresi PA; Marrie RA; Fitzgerald KC
- Article: PLOS ONE. 2022;17(11):e0278072Aboulatta L; Peymani P; Vaccaro C; Leong C; Kowalec K; Delaney J; Falk J; Alessi-Severini S; Aloud B; Eltonsy S
- Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(11):844-852Sigstrom R; Kowalec K; Jonsson L; Clements CC; Karlsson R; Nordenskjold A; Palsson E; Sullivan PF; Landen M
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e198Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hägg S; Hitchon C; Bernstein CN; Cutter G; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e31-e32Lu Y; Kowalec K; Werge T; Andreassen O; Sullivan P
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e270Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M; Lu Y
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e32-e33Kowalec K; Karlsson R; Lu Y; Song J; Yao S; Szatkiewicz J; Kähler A; Schalling M; Österholm A-M; Hultman C; Lavebratt C; Landen M; Karlsson H; Dalman C; Sullivan P
- Article: GENERAL HOSPITAL PSYCHIATRY. 2022;77:21-28Kowalec K; Salter A; Fitzgerald KC; Patel M; Han J; Lu Y; Bolton JM; Hitchon C; Bernstein CN; Patten S; Graff LA; Marriott JJ; Marrie RA
- Article: BMC RESEARCH NOTES. 2022;15(1):162Aboulatta L; Kowalec K; Delaney J; Alessi-Severini S; Leong C; Falk J; Eltonsy S
- Article: MOLECULAR PSYCHIATRY. 2022;27(5):2439-2447Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz JP; Larsson H; Lichtenstein P; Hultman CM; Sullivan PF
- Article: FRONTIERS IN PHARMACOLOGY. 2022;13:886652Leong C; Kowalec K; Eltonsy S; Bolton JM; Enns MW; Tan Q; Yogendran M; Chateau D; Delaney JA; Sareen J; Falk J; Spiwak R; Logsetty S; Alessi-Severini S
- Article: FRONTIERS IN PHARMACOLOGY. 2022;13:871136Shouman W; Delaney JA; Kowalec K; Ng M; Ruth C; Falk J; Leong C; Alessi-Severini S; Lavu A; Peymani P; Eltonsy S
- Article: MOLECULAR PSYCHIATRY. 2022;27(3):1667-1675Thuy-Dung N; Harder A; Xiong Y; Kowalec K; Hagg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan PF; Lu Y
- Article: JAMA PSYCHIATRY. 2022;79(3):260-269Pardinas AF; Smart SE; Willcocks IR; Holmans PA; Dennison CA; Lynham AJ; Legge SE; Baune BT; Bigdeli TB; Cairns MJ; Corvin A; Fanous AH; Frank J; Kelly B; McQuillin A; Melle I; Mortensen PB; Mowry BJ; Pato CN; Periyasamy S; Rietschel M; Rujescu D; Simonsen C; St Clair D; Tooney P; Wu JQ; Andreassen OA; Kowalec K; Sullivan PF; Murray RM; Owen MJ; MacCabe JH; O'Donovan MC; Walters JTR
- Article: ACR OPEN RHEUMATOLOGY. 2021;3(12):889-896Kowalec K; Carney H; Patel M; Hitchon C; Bolton JM; Patten SB; Graff LA; Bernstein CN; Peschken C; Marrie RA
- Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(13):2077-2084Harroud A; Marrie RA; Fitzgerald KC; Salter A; Lu Y; Patel M; Kowalec K
- Article: MOLECULAR PSYCHIATRY. 2021;26(8):4487-4495Kowalec K; Lu Y; Sariaslan A; Song J; Ploner A; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
- Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):163Kowalec K; Lu Y; Song J; Dalman C; Hultman CM; Larsson H; Lichtenstein P; Sullivan PF
- Article: ELIFE. 2021;10:e58430Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forti M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard CJ; Nenadic I; O'Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Sullivan P; Vassos E; Breen G; Collier DA; Murray RM; Schalkwyk LS; Mill J
- Article: INFLAMMATORY BOWEL DISEASES. 2021;27(1):58-64Carney H; Marrie RA; Bolton JM; Patten SB; Graff LA; Bernstein CN; Kowalec K
- Article: NEUROLOGY. 2020;95(5):e446-e456Salter A; Kowalec K; Fitzgerald KC; Cutter G; Marrie RA
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s236Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
- Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):157Kowalec K; Hannon H; Mansell G; Burrage J; Ori APS; Ophoff RA; Mill J; Sullivan PF
- Article: NATURE GENETICS. 2018;50(8):1081-1085Kowalec K; Wright GEB; Drogemoller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager PL; Denny JC; Davis MF; Ross CJD; Tremlett H; Carleton BC
- Article: NEUROLOGY. 2018;90(4):e332-e341McCormack M; Gui H; Ingason A; Speed D; Wright GEB; Zhang EJ; Secolin R; Yasuda C; Kwok M; Wolking S; Becker F; Rau S; Avbersek A; Heggeli K; Leu C; Depondt C; Sills GJ; Marson AG; Auce P; Brodie MJ; Francis B; Johnson MR; Koeleman BPC; Striano P; Coppola A; Zara F; Kunz WS; Sander JW; Lerche H; Klein KM; Weckhuysen S; Krenn M; Gudmundsson LJ; Stefansson K; Krause R; Shear N; Ross CJD; Delanty N; Pirmohamed M; Carleton BC; Cendes F; Lopes-Cendes I; Liao W-P; O'Brien TJ; Sisodiya SM; Cherny S; Kwan P; Baum L; Cavalleri GL
- Article: NEUROLOGY. 2017;89(24):2455-2461Kowalec K; McKay KA; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA
- Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:173Kowalec K; Wright GEB; Drögemöller BI; Aminkeng F; Bhavsar AP; Kingwell E; Yoshida EM; Traboulsee A; Marrie RA; Kremenchutzky M; Campbell TL; Duquette P; Chalasani N; Wadelius M; Hallberg P; Xia Z; De Jager P; Ross C; Tremlett H; Carleton B
- Journal article: JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. 2017;88:167Abel S; Aminkeng F; Kowalec K; Drogemoller B; Wright G; Bader R; Stortz J; Yoshida E; Lee S; Al-Judaibi B; Kim R; Tam E; Ramji A; Ross C; Carleton B
- Article: BMJ OPEN. 2017;7(5):e016276Kowalec K; Kingwell E; Carruthers R; Marrie RA; Bernatsky S; Traboulsee A; Ross CJD; Carleton B; Tremlett H
- Journal article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2017;12:1-3Mckay KA; Kowalec K; Brinkman F; Finlay BB; Horwitz M; Manges AR; Osborne L; Tremlett H
- Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2016;85(3):328-333Osiowy C; Kowalec K; Giles E
- Article: NATURE GENETICS. 2015;47(9):1079-1084Aminkeng F; Bhavsar AP; Visscher H; Rassekh SR; Li Y; Lee JW; Brunham LR; Caron HN; van Dalen EC; Kremer LC; van der Pal HJ; Amstutz U; Rieder MJ; Bernstein D; Carleton BC; Hayden MR; Ross CJD
- Article: JOURNAL OF VIRAL HEPATITIS. 2013;20(2):122-130Kowalec K; Minuk GY; Borresen ML; Koch A; McMahon BJ; Simons B; Osiowy C
- Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(1):57-59Kowalec K; Yoshida EM; Traboulsee A; Carleton B; Tremlett H
- Article: JOURNAL OF MEDICAL VIROLOGY. 2012;84(9):1369-1375Minuk GY; Kowalec K; Caouette S; Larke B; Osiowy C
- Article: JOURNAL OF MEDICAL VIROLOGY. 2010;82(6):942-948Osiowy C; Kaita K; Solar K; Mendoza K
- Show more
All other publications
- Preprint: MEDRXIV. 2023Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Giusti-Rodríguez P; Sullivan PF; Yao S
- Review: FRONTIERS IN IMMUNOLOGY. 2023;14:1197195Marrie RA; Fisk JD; Fitzgerald K; Kowalec K; Maxwell C; Rotstein D; Salter A; Tremlett H
- Preprint: RES SQ. 2023;RES SQLu Y; Xiong Y; Karlsson R; Song J; Kowalec K; Rück C; Sigstrom R; Jonsson L; Clements C; Andersson E; Boberg J; Lewis C; Sullivan P; Landén M
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E159Kowalec K; Song J; Yao S; Karlsson R; Lu Y; Bergen S; Harder A; Kahler A; Osterholm A-M; Hultman C; Sullivan P
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):212Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hagg S; Hitchon C; Bernstein CN; Cutter G; Marriott JJ; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
- Preprint: MEDRXIV. 2022Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Chateau D; Tan Q; Kearns K; Raimondi C; Lavu A; Haidar L; Vaccaro C; Eltonsy S
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(1_SUPPL):52Hu C; Marrie RA; Salter A; Kowalec K; Fitzgerald K
- Conference publication: BIRTH DEFECTS RESEARCH. 2022;114(9):395Aboulatta L; Kowalec K; Leong C; Delaney J; Falk J; Alessi-Severini S; Eltonsy S
- Review: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2022;111(4):919-930Johnson D; Wilke MAP; Lyle SM; Kowalec K; Jorgensen A; Wright GEB; Drogemoller BI
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E137-E138Song J; Yao S; Kowalec K; Lu Y; Sariaslan A; Szatkiewicz J; Larsson H; Lichtenstein P; Hultman C; Sullivan P
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E237Yao S; Lu Y; Kowalec K; Song J; Karlsson R; Harder A; Sullivan P
- Review: PSYCHOLOGICAL MEDICINE. 2021;51(13):2168-2177Legge SE; Santoro ML; Periyasamy S; Okewole A; Arsalan A; Kowalec K
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(1_SUPPL):58-59Harroud A; Marrie R; Richards B; Fitzgerald K; Salter A; Lu Y; Patel M; Kowalec K
- Preprint: MEDRXIV. 2021Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan P; Lu Y
- Preprint: BIORXIV. 2020Hannon E; Dempster EL; Mansell G; Burrage J; Bass N; Bohlken MM; Corvin A; Curtis CJ; Dempster D; Di Forta M; Dinan TG; Donohoe G; Gaughran F; Gill M; Gillespie A; Gunasinghe C; Hulshoff HE; Hultman CM; Johansson V; Kahn RS; Kaprio J; Kenis G; Kowalec K; MacCabe J; McDonald C; McQuillin A; Morris DW; Murphy KC; Mustard C; Nenadic I; O’Donovan MC; Quattrone D; Richards AL; Rutten BP; St Clair D; Therman S; Toulopoulou T; Van Os J; Waddington JL; Consortium WTCC; consortium CA; Sullivan P; Vassos E; Breen G; Collier DA; Murray R; Schalkwyk LS; Mill J
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S184Lu Y; Kowalec K; Drange OK; Tesli M; Weinsheimer S; Folkersen L; Werge T; Andreassen O; Reichborn-Kjennerud T; Sullivan P
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S85-S86Kowalec K; Yi L; Drange OK; Weinsheimer S; Tesli M; Folkersen L; Werge T; Andreassen OA; Reichborn-Kjennerud T; Sullivan P
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S215Kowalec K; Yi L; Sariaslan A; Song J; Ploner A; Dalman C; Hultman C; Larsson H; Lichtenstein P; Sullivan P
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:648Kowalec K; Bernstein CN; Hitchon C; Bolton J; Marrie RA
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1099-1100Hannon E; Dempster E; Mansell G; Schalkwyk L; Murray R; McQuillin A; Kowalec K; St Clair D; Morris D; Sullivan P; O'Donovan M; MacCabe J; Collier D; Mill J
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1332-1333Kowalec K; Hannon E; Mansell G; Burrage J; Mill J; Sullivan P
- Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2017;23:991Kowalec K; McKay K; Patten SB; Fisk JD; Evans C; Tremlett H; Marrie RA
- Review: EXPERT OPINION ON DRUG SAFETY. 2014;13(10):1305-1317Kowalec K; Kingwell E; Yoshida EM; Marrie RA; Kremenchutzky M; Campbell TL; Wadelius M; Carleton B; Tremlett H
- Review: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2013;2(3):183-192Kowalec K; Carleton B; Tremlett H
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Grants
- Capitalising on our differences: A gathering to better understand and advocate for Early Career Health Researchers in CanadaCanadian Institutes of Health Research1 January 2023 - 31 December 2023
- Precision Genomics SuiteCanada Foundation for Innovation22 November 2022Neurogenomics, Pharmacogenomics, Precision Medicine Automated preparation of samples for precise genomic analyses
- Psychiatric Disorder Genomic Risk Scores as a Correlate of Disease Activity and Progression in Multiple SclerosisCongressionally Directed Medical Research Programs15 July 2020 - 14 July 2024
- Enhancing CAN-AIM capacity to respond to drug safety and effectiveness queriesCanadian Institutes of Health Research1 September 2019 - 31 August 2022
- Identifying Clinical, Demographic, & Genomic Risk Factors for Treatment-Resistant Psychiatric DisordersCanadian Institutes of Health Research1 April 2018 - 3 January 2019
- The Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT) ProgramCanadian Institutes of Health Research1 November 2015 - 28 February 2022
- Genotype specific approaches to beta-interferon therapy in Multiple SclerosisCanadian Institutes of Health Research1 May 2011 - 31 October 2014
Employments
- Assistant Professor, Genetics, University of Manitoba, 2019-
- Affiliated to Research, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2025-2027
Degrees and Education
- PhD, Genetics and epidemiology, University of British Columbia, 2016
- MSc, Viral genetics, University of Manitoba, 2011
- BSc, Microbiology, University of Manitoba, 2008