Johan Frostegård

Om mig
Publikationer
Populärvetenskap och samverkan

Forskningsbeskrivning

Professor i medicin vid Institutet för miljömedicin och chef för enheten för immunologi och kronisk sjukdom. Forskar i huvudsak om hur olika sorters fetter, främst fosfolipider, kan aktivera immunreaktioner, samt hur dessa påverkar ateroskleros, hjärt-kärlsjukdom och inflammation i övrigt. Forskningen är såväl experimentell som kliniskt orienterad.

Artiklar

Article: SCIENTIFIC REPORTS. 2023;13(1):15011

Antibodies against malondialdehyde among 60-year-olds: prediction of cardiovascular disease

Samal SK; Leander K; Vikstroem M; Griesbaum L; de Faire U; Frostegard J
Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:809007

Antibodies Against Phosphorylcholine Among 60-Year-Olds: Clinical Role and Simulated Interactions

Samal SK; Panda PK; Vikstrom M; Leander K; de Faire U; Ahuja R; Frostegard J
Article: SCIENTIFIC REPORTS. 2021;11(1):20246

Antibodies against phosphorylcholine in hospitalized versus non-hospitalized obese subjects

Jujic A; Korduner J; Holm H; Engstrom G; Bachus E; Bhattacharya P; Nilsson PM; Frostegard J; Magnusson M
Article: ACR OPEN RHEUMATOLOGY. 2021;3(9):642-653

Effects of Atorvastatin on T-Cell Activation and Apoptosis in Systemic Lupus Erythematosus and Novel Simulated Interactions With C-Reactive Protein and Interleukin 6

Sun J; Panda PK; Samal SK; Ahuja R; Ajeganova S; Hafstrom I; Liu A; Frostegard J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):201

Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events

Ajeganova S; Andersson MLE; Frostegard J; Hafstrom I
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(1):141-156

Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases

Vries MR; Ewing MM; Jong RCM; MacArthur MR; Karper JC; Peters EAB; Nordzell M; Karabina SAP; Sexton D; Dahlbom I; Bergman A; Mitchell JR; Frostegard J; Kuiper J; Ninio E; Jukema JW; Pettersson K; Quax PHA
Article: SCIENTIFIC REPORTS. 2021;11(1):12120

Potential natural immunization against atherosclerosis in hibernating bears

Samal SK; Frobert O; Kindberg J; Stenvinkel P; Frostegard J
Article: ARTHRITIS & RHEUMATOLOGY. 2021;73(6):1073-1085

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases

Barturen G; Babaei S; Catala-Moll F; Martinez-Bueno M; Makowska Z; Martorell-Marugan J; Carmona-Saez P; Toro-Dominguez D; Carnero-Montoro E; Teruel M; Kerick M; Acosta-Herrera M; Le Lann L; Jamin C; Rodriguez-Ubreva J; Garcia-Gomez A; Kageyama J; Buttgereit A; Hayat S; Mueller J; Lesche R; Hernandez-Fuentes M; Juarez M; Rowley T; White I; Maranon C; Gomes Anjos T; Varela N; Aguilar-Quesada R; Garrancho FJ; Lopez-Berrio A; Rodriguez Maresca M; Navarro-Linares H; Almeida I; Azevedo N; Brandao M; Campar A; Faria R; Farinha F; Marinho A; Neves E; Tavares A; Vasconcelos C; Trombetta E; Montanelli G; Vigone B; Alvarez-Errico D; Li T; Thiagaran D; Blanco Alonso R; Corrales Martinez A; Genre F; Lopez Mejias R; Gonzalez-Gay MA; Remuzgo S; Ubilla Garcia B; Cervera R; Espinosa G; Rodriguez-Pinto I; De Langhe E; Cremer J; Lories R; Belz D; Hunzelmann N; Baerlecken N; Kniesch K; Witte T; Lehner M; Stummvoll G; Zauner M; Aguirre-Zamorano MA; Barbarroja N; Castro-Villegas MC; Collantes-Estevez E; de Ramon E; Diaz Quintero I; Escudero-Contreras A; Fernandez Roldan MC; Jimenez Gomez Y; Jimenez Moleon I; Lopez-Pedrera R; Ortega-Castro R; Ortego N; Raya E; Artusi C; Gerosa M; Meroni PL; Schioppo T; De Groof A; Ducreux J; Lauwerys B; Maudoux A-L; Cornec D; Devauchelle-Pensec V; Jousse-Joulin S; Jouve P-E; Rouviere B; Saraux A; Simon Q; Alvarez M; Chizzolini C; Dufour A; Wynar D; Balog A; Bocskai M; Deak M; Dulic S; Kadar G; Kovacs L; Cheng Q; Gerl V; Hiepe F; Khodadadi L; Thiel S; de Rinaldis E; Rao S; Benschop RJ; Chamberlain C; Dow ER; Ioannou Y; Laigle L; Marovac J; Wojcik J; Renaudineau Y; Borghi MO; Frostegard J; Martin J; Beretta L; Ballestar E; McDonald F; Pers J-O; Alarcon-Riquelme ME
Article: LUPUS SCIENCE & MEDICINE. 2021;8(1):e000454

Patients with SLE have higher risk of cardiovascular events and mortality in comparison with controls with the same levels of traditional risk factors and intima-media measures, which is related to accumulated disease damage and antiphospholipid syndrome: a case-control study over 10 years

Ajeganova S; Hafstrom I; Frostegard J
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):32

Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-α: potential underlying mechanisms

Frostegard J; Ahmed S; Hafstrom I; Ajeganova S; Rahman M
Article: JOURNAL OF TRANSLATIONAL AUTOIMMUNITY. 2021;4:100090

An elevated polyclonal free light chain level reflects a strong interferon signature in patients with systemic autoimmune diseases

Bettacchioli E; Le Gaffric C; Mazeas M; Borghi MO; Frostegard J; Barturen G; Makowska Z; Babei S; Lesche R; Meroni PL; Alarcon-Riquelme ME; Renaudineau Y
Article: BMC CARDIOVASCULAR DISORDERS. 2020;20(1):524

C-reactive protein in traditional melanesians on Kitava

Carrera-Bastos P; Fontes-Villalba M; Gurven M; Muskiet FAJ; Akerfeldt T; Lindblad U; Rastam L; Frostegard J; Shapira Y; Shoenfeld Y; Granfeldt Y; Sundquist K; Jonsson T
Article: JOURNAL OF AUTOIMMUNITY. 2020;115:102524

Antiphospholipid autoantibody detection is important in all patients with systemic autoimmune diseases

Marziale A; Bettacchioli E; Picart G; Nafai S; Galinat H; Meroni PL; Frostegard J; Alarcon-Riquelme ME; Renaudineau Y
Article: JOURNAL OF IMMUNOLOGY. 2020;205(8):2109-2116

Antibodies against Phosphorylcholine and Malondialdehyde during the First Two Years of Life

Thiagarajan D; Lundstrom SL; Pershagen G; Malmros CA; Andolf E; Hedman A; Berg O; Oparina N; Frostegard J
Article: SCIENTIFIC REPORTS. 2020;10(1):11010

IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

Thiagarajan D; Oparina N; Lundstrom S; Zubarev R; Sun J; Alarcon-Riquelme M; Frostegard J
Article: LUPUS. 2020;29(8):825-835

Proprotein convertase subtilisin kexin 9 is associated with disease activity and is implicated in immune activation in systemic lupus erythematosus

Liu A; Rahman M; Hafstrom I; Ajeganova S; Frostegard J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2020;201(1):94-104

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

Samal SK; Qureshi AR; Rahman M; Stenvinkel P; Frostegard J
Article: ACR OPEN RHEUMATOLOGY. 2020;2(6):344-356

Immunoglobulin G1 Antibodies Against Phosphorylcholine Are Associated With Protection in Systemic Lupus Erythematosus and Atherosclerosis: Potential Underlying Mechanisms

Thiagarajan D; Fiskesund R; Frostegard A; Steen J; Rahman M; Vikstroem M; Lundstroem S; Frostegard J
Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(4):422-434

Phenotypic features of vascular calcification in chronic kidney disease

Dai L; Debowska M; Lukaszuk T; Bobrowski L; Barany P; Soderberg M; Thiagarajan D; Frostegard J; Wennberg L; Lindholm B; Qureshi AR; Waniewski J; Stenvinkel P
Article: JOURNAL OF CLINICAL MEDICINE. 2020;9(3):E753-753

Antibodies against Malondialdehyde in Haemodialysis Patients and Its Association with Clinical Outcomes: Differences between Subclasses and Isotypes

Samal SK; Qureshi AR; Rahman M; Stenvinkel P; Frostegard J
Article: LUPUS SCIENCE & MEDICINE. 2020;7(1):e000362

Similar progression of carotid intima-media thickness in 7-year surveillance of patients with mild SLE and controls, but this progression is still promoted by dyslipidaemia, lower HDL levels, hypertension, history of lupus nephritis and a higher prednisolone usage in patients

Ajeganova S; Gustafsson T; Lindberg L; Hafstrom I; Frostegard J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2019;4(4):480-494

Malondialdehyde Conjugated With Albumin Induces Pro-Inflammatory Activation of T Cells Isolated From Human Atherosclerotic Plaques Both Directly and Via Dendritic Cell-Mediated Mechanism

Rahman M; Steuer J; Gillgren P; Vegvari A; Liu A; Frostegard J
Article: LUPUS. 2018;27(10):1670-1678

Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus

Frostegard J; Hellstrom C; Nilsson P; Frostegard AG; Ajeganova S
Article: CLINICAL RHEUMATOLOGY. 2018;37(7):1825-1834

Variation in pain related to systemic lupus erythematosus (SLE): a 7-year follow-up study

Waldheim E; Ajeganova S; Bergman S; Frostegard J; Welin E
Article: HUMAN MOLECULAR GENETICS. 2018;27(10):1809-1818

A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Chen X; Gustafsson S; Whitington T; Borne Y; Lorentzen E; Sun J; Almgren P; Su J; Karlsson R; Song J; Lu Y; Zhan Y; Hagg S; Svensson P; Smedby KE; Slager SL; Ingelsson E; Lindgren CM; Morris AP; Melander O; Karlsson T; de Faire U; Caidahl K; Engstrom G; Lind L; Karlsson MCI; Pedersen NL; Frostegard J; Magnusson PKE
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2018;36(3):428-433

Association between dietary and metabolic factors and IgM antibodies to phosphorylcholine and malondialdehyde in patients with systemic lupus erythematosus and population-based matched controls

Lourdudoss C; Ajeganova S; Frostegard J
Article: JOURNAL OF INTERNAL MEDICINE. 2018;284(2):193-210

PCSK9 plays a novel immunological role in oxidized LDL-induced dendritic cell maturation and activation of T cells from human blood and atherosclerotic plaque

Liu A; Frostegard J
Article: ATHEROSCLEROSIS. 2018;268:36-48

IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors

Sun J; Lundstrom SL; Zhang B; Zubarev RA; Steuer J; Gillgren P; Rahman M; Ajeganova S; Liu A; Frostegard J
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2017;6(11):e006778

Induction of Dendritic Cell-Mediated Activation of T Cells From Atherosclerotic Plaques by Human Heat Shock Protein 60

Rahman M; Steuer J; Gillgren P; Hayderi A; Liu A; Frostegard J
Article: NATURE COMMUNICATIONS. 2017;8:16021

Transancestral mapping and genetic load in systemic lupus erythematosus

Langefeld CD; Ainsworth HC; Graham DSC; Kelly JA; Comeau ME; Marion MC; Howard TD; Ramos PS; Croker JA; Morris DL; Sandling JK; Almlof JC; Acevedo-Vasquez EM; Alarcon GS; Babini AM; Baca V; Bengtsson AA; Berbotto GA; Bijl M; Brown EE; Brunner HI; Cardiel MH; Catoggio L; Cervera R; Cucho-Venegas JM; Dahlqvist SR; D'Alfonso S; Da Silva BM; de la Rua Figueroa I; Doria A; Edberg JC; Endreffy E; Esquivel-Valerio JA; Fortin PR; Freedman BI; Frostegard J; Garcia MA; Garcia de la Torre I; Gilkeson GS; Gladman DD; Gunnarsson I; Guthridge JM; Huggins JL; James JA; Kallenberg CGM; Kamen DL; Karp DR; Kaufman KM; Kottyan LC; Kovacs L; Laustrup H; Lauwerys BR; Li Q-Z; Maradiaga-Cecena MA; Martin J; McCune JM; McWilliams DR; Merrill JT; Miranda P; Moctezuma JF; Nath SK; Niewold TB; Orozco L; Ortego-Centeno N; Petri M; Pineau CA; Pons-Estel BA; Pope J; Raj P; Ramsey-Goldman R; Reveille JD; Russell LP; Sabio JM; Aguilar-Salinas CA; Scherbarth HR; Scorza R; Seldin MF; Sjowall C; Svenungsson E; Thompson SD; Toloza SMA; Truedsson L; Tusie-Luna T; Vasconcelos C; Vila LM; Wallace DJ; Weisman MH; Wither JE; Bhangale T; Oksenberg JR; Rioux JD; Gregersen PK; Syvanen A-C; Ronnblom L; Criswell LA; Jacob CO; Sivils KL; Tsao BP; Schanberg LE; Behrens TW; Silverman ED; Alarcon-Riquelme ME; Kimberly RP; Harley JB; Wakeland EK; Graham RR; Gaffney PM; Vyse TJ
Article: LAKARTIDNINGEN. 2017;114:EH7W

[Small fatty substances may be of great importance in the development of atherosclerosis].

Frostegård J
Article: IMMUNOLOGICAL INVESTIGATIONS. 2017;46(1):59-69

Antibodies against Phosphorylcholine among New Guineans Compared to Swedes: An Aspect of the Hygiene/Missing Old Friends Hypothesis

Frostegard J; Tao W; Rastam L; Lindblad U; Lindeberg S
Article: ARTHRITIS & RHEUMATOLOGY. 2017;69(1):131-142

Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus

An J; Briggs TA; Dumax-Vorzet A; Alarcon-Riquelme ME; Belot A; Beresford M; Bruce IN; Carvalho C; Chaperot L; Frostegard J; Plumas J; Rice GI; Vyse TJ; Wiedeman A; Crow YJ; Elkon KB
Article: PLOS ONE. 2017;12(4):e0171195

IgM antibodies to oxidized phosphatidylserine as protection markers in cardiovascular disease among 60-year olds

Frostegard J; Su J; Sing S; Hua X; Vikstrom M; Leander K; Gigante B; de Faire U; Frostegard AG
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(12):e004415

Human IgM Antibodies to Malondialdehyde Conjugated With Albumin Are Negatively Associated With Cardiovascular Disease Among 60-Year-Olds

Thiagarajan D; Frostegard AG; Singh S; Rahman M; Liu A; Vikstrom M; Leander K; Gigante B; Hellenius M-L; Zhang B; Zubarev RA; de Faire U; Lundstrom SL; Frostegard J
Article: LUPUS. 2016;25(14):1602-1609

Dietary micronutrient intake and atherosclerosis in systemic lupus erythematosus

Lourdudoss C; Elkan A-C; Hafstrom I; Jogestrand T; Gustafsson T; van Vollenhoven R; Frostegard J
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(9):e003976

Oxidized Low-Density Lipoprotein (OxLDL)-Treated Dendritic Cells Promote Activation of T Cells in Human Atherosclerotic Plaque and Blood, Which Is Repressed by Statins: microRNA let-7c Is Integral to the Effect

Frostegard J; Zhang Y; Sun J; Yan K; Liu A
Article: CLINICAL IMMUNOLOGY. 2016;166:27-37

IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms

Rahman M; Sing S; Golabkesh Z; Fiskesund R; Gustafsson T; Jogestrand T; Frostegard AG; Hafstrom I; Liu A; Frostegard J
Article: LUPUS SCIENCE & MEDICINE. 2016;3(1):e000135

The association between diet and glucocorticoid treatment in patients with SLE.

Lourdudoss C; Hafström I; Frostegård J; van Vollenhoven R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(1):242-252

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Zhao J; Giles BM; Taylor RL; Yette GA; Lough KM; Ng HL; Abraham LJ; Wu H; Kelly JA; Glenn SB; Adler AJ; Williams AH; Comeau ME; Ziegler JT; Marion M; Alarcon-Riquelme ME; Alarcon GS; Anaya J-M; Bae S-C; Kim D; Lee H-S; Criswell LA; Freedman BI; Gilkeson GS; Guthridge JM; Jacob CO; James JA; Kamen DL; Merrill JT; Sivils KM; Niewold TB; Petri MA; Ramsey-Goldman R; Reveille JD; Scofield RH; Stevens AM; Vila LM; Vyse TJ; Kaufman KM; Harley JB; Langefeld CD; Gaffney PM; Brown EE; Edberg JC; Kimberly RP; Ulgiati D; Tsao BP; Boackle SA
Article: CLINICAL IMMUNOLOGY. 2015;161(2):157-162

Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

Zhao J; Wu H; Langefeld CD; Kaufman KM; Kelly JA; Bae S-C; Alarcon-Riquelme ME; Alarcon GS; Anaya J-M; Criswell LA; Freedman BI; Kamen DL; Gilkeson GS; Jacob CO; James JA; Merrill JT; Gaffney PM; Sivils KM; Niewold TB; Petri MA; Song ST; Jeong H-J; Ramsey-Goldman R; Reveille JD; Scofield RH; Stevens AM; Boackle SA; Vila LM; Chang D-M; Song YW; Vyse TJ; Harley JB; Brown EE; Edberg JC; Kimberly RP; Hahn BH; Grossman JM; Tsao BP; La Cava A
Article: JOURNAL OF DIABETES AND ITS COMPLICATIONS. 2015;29(8):1152-1158

Coenzyme Q10 and oxidative stress, the association with peripheral sensory neuropathy and cardiovascular disease in type 2 diabetes mellitus

Forsberg E; Xu C; Grunler J; Frostegard J; Tekle M; Brismar K; Karvestedt L
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):84

Bone mineral density and carotid atherosclerosis in systemic lupus erythematosus: a controlled cross-sectional study

Ajeganova S; Gustafsson T; Jogestrand T; Frostegard J; Hafstrom I
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(3):e14

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6

Oparina NY; Delgado-Vega AM; Martinez-Bueno M; Magro-Checa C; Fernandez C; Ortega Castro R; Pons-Estel BA; D'Alfonso S; Sebastiani GD; Witte T; Lauwerys BR; Endreffy E; Kovacs L; Escudero A; Lopez-Pedrera C; Vasconcelos C; da Silva BM; Frostegard J; Truedsson L; Martin J; Raya E; Ortego-Centeno N; de los Angeles Aguirre M; de Ramon Garrido E; Castillo Palma M-J; Alarcon-Riquelme ME; Kozyrev SV
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(1):197-205

Induction of Dendritic Cell-Mediated T-Cell Activation by Modified but Not Native Low-Density Lipoprotein in Humans and Inhibition by Annexin A5 Involvement of Heat Shock Proteins

Liu A; Ming JY; Fiskesund R; Ninio E; Karabina S-A; Bergmark C; Frostegard AG; Frostegard J
Article: ATHEROSCLEROSIS. 2014;236(2):394-399

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men

Gigante B; Leander K; Vikstrom M; Baldassarre D; Veglia F; Strawbridge RJ; McLeod O; Gertow K; Sennblad B; Shah S; Zabaneh D; Humphries SE; Kauhanen JP; Rauramaa R; Smit AJ; Mannarino E; Giral P; Tremoli E; Hamsten A; Frostegard J; De Faire U
Article: ATHEROSCLEROSIS. 2014;235(2):592-598

Oxidized but not native cardiolipin has pro-inflammatory effects, which are inhibited by Annexin A5

Wan M; Hua X; Su J; Thiagarajan D; Frostegard AG; Haeggstrom JZ; Frostegard J
Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4551-4559

Naturally Occurring Human Phosphorylcholine Antibodies Are Predominantly Products of Affinity-Matured B Cells in the Adult

Fiskesund R; Steen J; Amara K; Murray F; Szwajda A; Liu A; Douagi I; Malmstrom V; Frostegard J
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;94(4):586-598

Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription

Guthridge JM; Lu R; Sun H; Sun C; Wiley GB; Dominguez N; Macwana SR; Lessard CJ; Kim-Howard X; Cobb BL; Kaufman KM; Kelly JA; Langefeld CD; Adler AJ; Harley ITW; Merrill JT; Gilkeson GS; Kamen DL; Niewold TB; Brown EE; Edberg JC; Petri MA; Ramsey-Goldman R; Reveille JD; Vila LM; Kimberly RP; Freedman BI; Stevens AM; Boackle SA; Criswell LA; Vyse TJ; Behrens TW; Jacob CO; Alarcon-Riquelme ME; Sivils KL; Choi J; Joo YB; Bang S-Y; Lee H-S; Bae S-C; Shen N; Qian X; Tsao BP; Scofield RH; Harley JB; Webb CF; Wakeland EK; James JA; Nath SK; Graham RR; Gaffney PM
Article: PLOS ONE. 2014;9(9):e106584

IgM-Antibodies against Phosphorylcholine in Mothers and Normal or Low Birth Weight Term Newborn Infants

Frostegard AG; Sjoberg BG; Frostegard J; Norman M
Article: PLOS ONE. 2014;9(12):e111764

Antibodies against Native and Oxidized Cardiolipin and Phosphatidylserine and Phosphorylcholine in Atherosclerosis Development

Frostegard AG; Su J; Hua X; Vikstrom M; de Faire U; Frostegard J
Article: JOURNAL OF RHEUMATOLOGY. 2013;40(12):1958-1966

Disease Factors in Early Rheumatoid Arthritis Are Associated with Differential Risks for Cardiovascular Events and Mortality Depending on Age at Onset: A 10-year Observational Cohort Study

Ajeganova S; Andersson MLE; Frostegard J; Hafstrom I
Article: JOURNAL OF RHEUMATOLOGY. 2013;40(11):1856-1864

Low Levels of Antibodies Against Oxidized but not Nonoxidized Cardiolipin and Phosphatidylserine Are Associated with Atherosclerotic Plaques in Systemic Lupus Erythematosus

Su J; Frostegard AG; Hua X; Gustafsson T; Jogestrand T; Hafstrom I; Frostegard J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;174(3):441-448

Immunoglobulin (Ig)M antibodies against oxidized cardiolipin but not native cardiolipin are novel biomarkers in haemodialysis patients, associated negatively with mortality

Frostegard AG; Hua X; Su J; Carrero JJ; Heimburger O; Barany P; Stenvinkel P; Frostegard J
Article: LUPUS. 2013;22(11):1118-1127

Health-related quality of life, fatigue and mood in patients with SLE and high levels of pain compared to controls and patients with low levels of pain

Waldheim E; Elkan A-C; Pettersson S; van Vollenhoven R; Bergman S; Frostegard J; Henriksson EW
Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2013;106:72-78

Annexin A5 inhibits atherogenic and pro-inflammatory effects of lysophosphatidylcholine

Domeij H; Hua X; Su J; Backlund A; Yan Z; Frostegard AG; Haeggstrom JZ; Modeer T; Frostegard J
Article: HUMAN MOLECULAR GENETICS. 2013;22(19):4021-4029

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci

Martin J-E; Assassi S; Diaz-Gallo L-M; Broen JC; Simeon CP; Castellvi I; Vicente-Rabaneda E; Fonollosa V; Ortego-Centeno N; Gonzalez-Gay MA; Espinosa G; Carreira P; Camps M; Sabio JM; D'alfonso S; Vonk MC; Voskuyl AE; Schuerwegh AJ; Kreuter A; Witte T; Riemekasten G; Hunzelmann N; Airo P; Beretta L; Scorza R; Lunardi C; Van Laar J; Chee MM; Worthington J; Herrick A; Denton C; Fonseca C; Tan FK; Arnett F; Zhou X; Reveille JD; Gorlova O; Koeleman BPC; Radstake TRDJ; Vyse T; Mayes MD; Alarcon-Riquelme ME; Martin J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;167(2):464-469

IgM-phosphorylcholine autoantibodies and outcome in acute coronary syndromes

Caidahl K; Hartford M; Karlsson T; Herlitz J; Pettersson K; de Faire U; Frostegard J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2013;72(3):437-444

Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups

Kaufman KM; Zhao J; Kelly JA; Hughes T; Adler A; Sanchez E; Ojwang JO; Langefeld CD; Ziegler JT; Williams AH; Comeau ME; Marion MC; Glenn SB; Cantor RM; Grossman JM; Hahn BH; Song YW; Yu C-Y; James JA; Guthridge JM; Brown EE; Alarcon GS; Kimberly RP; Edberg JC; Ramsey-Goldman R; Petri MA; Reveille JD; Vila LM; Anaya J-M; Boackle SA; Stevens AM; Freedman BI; Criswell LA; Pons-Estel BA; Lee J-H; Lee J-S; Chang D-M; Scofield RHA; Gilkeson GS; Merrill JT; Niewold TB; Vyse TJ; Bae S-C; Alarcon-Riquelme ME; Jacob CO; Sivils KM; Gaffney PM; Harley JB; Sawalha AH; Tsao BP
Article: LUPUS. 2013;22(2):136-143

Extent and characteristics of self-reported pain in patients with systemic lupus erythematosus

Waldheim E; Elkan A-C; Bergman S; Frostegard J; van Vollenhoven R; Henriksson EW
Article: BMC CARDIOVASCULAR DISORDERS. 2013;13:1

Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study

Su J; Hua X; Vikstrom M; Leander K; Gigante B; Hellenius M-L; de Faire U; Frostegard J
Article: PLOS GENETICS. 2013;9(10):e1003870

Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression

Sakurai D; Zhao J; Deng Y; Kelly JA; Brown EE; Harley JB; Bae S-C; Alarcon-Riqueime ME; Edberg JC; Kimberly RP; Ramsey-Goldman R; Petri MA; Reveille JD; Vila LM; Alarcon GS; Kaufman KM; Vyse TJ; Jacob CO; Gaffney PM; Sivils KM; James JA; Kamen DL; Gilkeson GS; Niewold TB; Merrill JT; Scofield RH; Criswell LA; Stevens AM; Boackle SA; Kim J-H; Choi J; Pons-Estel BA; Freedman BI; Anaya J-M; Martin J; Yu CY; Chang D-M; Song YW; Langefeld CD; Chen W; Grossman JM; Cantor RM; Hahn BH; Tsao BP
Article: PLOS ONE. 2013;8(8):e69404

PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Namjou B; Kim-Howard X; Sun C; Adler A; Chung SA; Kaufman KM; Kelly JA; Glenn SB; Guthridge JM; Scofield RH; Kimberly RP; Brown EE; Alarcon GS; Edberg JC; Kim J-H; Choi J; Ramsey-Goldman R; Petri MA; Reveille JD; Vila LM; Boackle SA; Freedman BI; Tsao BP; Langefeld CD; Vyse TJ; Jacob CO; Pons-Estel B; Niewold TB; Sivils KLM; Merrill JT; Anaya J-M; Gilkeson GS; Gaffney PM; Bae S-C; Alarcon-Riquelme ME; Harley JB; Criswell LA; James JA; Nath SK
Article: PLOS GENETICS. 2013;9(2):e1003336

MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus

Deng Y; Zhao J; Sakurai D; Kaufman KM; Edberg JC; Kimberly RP; Kamen DL; Gilkeson GS; Jacob CO; Scofield H; Langefeld CD; Kelly JA; Ramsey-Goldman R; Petri MA; Reveille JD; Vila LM; Alarcon GS; Vyse TJ; Pons-Estel BA; Freedman BI; Gaffney PM; Sivils KM; James JA; Gregersen PK; Anaya J-M; Niewold TB; Merrill JT; Criswell LA; Stevens AM; Boackle SA; Cantor RM; Chen W; Grossman JM; Hahn BH; Harley JB; Alarcon-Riquelme ME; Brown EE; Tsao BP
Article: PLOS GENETICS. 2013;9(2):e1003222

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

Molineros JE; Maiti AK; Sun C; Looger LL; Han S; Kim-Howard X; Glenn S; Adler A; Kelly JA; Niewold TB; Gilkeson GS; Brown EE; Alarcon GS; Edberg JC; Petri M; Ramsey-Goldman R; Reveille JD; Vila LM; Freedman BI; Tsao BP; Criswell LA; Jacob CO; Moore JH; Vyse TJ; Langefeld CL; Guthridge JM; Gaffney PM; Moser KL; Scofield RH; Alarcon-Riquelme ME; Williams SM; Merrill JT; James JA; Kaufman KM; Kimberly RP; Harley JB; Nath SK
Article: LUPUS. 2012;21(13):1405-1411

Diet and fatty acid pattern among patients with SLE: associations with disease activity, blood lipids and atherosclerosis

Elkan A-C; Anania C; Gustafsson T; Jogestrand T; Hafstrom I; Frostegard J
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(11):3695-3705

Association of Two Independent Functional Risk Haplotypes in TNIP1 With Systemic Lupus Erythematosus

Adrianto I; Wang S; Wiley GB; Lessard CJ; Kelly JA; Adler AJ; Glenn SB; Williams AH; Ziegler JT; Comeau ME; Marion MC; Wakeland BE; Liang C; Kaufman KM; Guthridge JM; Alarcon-Riquelme ME; Alarcon GS; Anaya J-M; Bae S-C; Kim J-H; Joo YB; Boackle SA; Brown EE; Petri MA; Ramsey-Goldman R; Reveille JD; Vila LM; Criswell LA; Edberg JC; Freedman BI; Gilkeson GS; Jacob CO; James JA; Kamen DL; Kimberly RP; Martin J; Merrill JT; Niewold TB; Pons-Estel BA; Scofield RH; Stevens AM; Tsao BP; Vyse TJ; Langefeld CD; Harley JB; Wakeland EK; Moser KL; Montgomery CG; Gaffney PM
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(11):1809-1814

Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

Kim K; Brown EE; Choi C-B; Alarc ME; Kelly JA; Glenn SB; Ojwang JO; Adler A; Lee H-S; Boackle SA; Criswell LA; Alarc GS; Edberg JC; Stevens AM; Jacob CO; Gilkeson GS; Kamen DL; Tsao BP; Anaya J-M; Guthridge JM; Nath SK; Richardson B; Sawalha AH; Kang YM; Shim SC; Suh C-H; Lee S-K; Kim C-S; Merrill JT; Petri M; Ramsey-Goldman R; Vil LM; Niewold TB; Martin J; Pons-Estel BA; Vyse TJ; Freedman BI; Moser KL; Gaffney PM; Williams A; Comeau M; Reveille JD; James JA; Eld RHS; Langefeld CD; Kaufman KM; Harley JB; Kang C; Kimberly RP; Bae S-C
Article: GENES AND IMMUNITY. 2012;13(5):380-387

A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus

Wang S; Adrianto I; Wiley GB; Lessard CJ; Kelly JA; Adler AJ; Glenn SB; Williams AH; Ziegler JT; Comeau ME; Marion MC; Wakeland BE; Liang C; Kaufman KM; Guthridge JM; Alarcon-Riquelme ME; Alarcon GS; Anaya J-M; Bae S-C; Kim J-H; Joo YB; Boackle SA; Brown EE; Petri MA; Ramsey-Goldman R; Reveille JD; Vila LM; Criswell LA; Edberg JC; Freedman BI; Gilkeson GS; Jacob CO; James JA; Kamen DL; Kimberly RP; Martin J; Merrill JT; Niewold TB; Pons-Estel BA; Scofield RH; Stevens AM; Tsao BP; Vyse TJ; Langefeld CD; Harley JB; Wakeland EK; Moser KL; Montgomery CG; Gaffney PM
Article: LUPUS. 2012;21(8):815-820

Microcirculation as determined by iontophoresis in SLE-patients and controls

Anania C; Norman M; Heimburger M; Gustafsson T; Jogestrand T; Hafstrom I; Frostegard J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(7):1219-1226

Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein

Delgado-Vega AM; Dozmorov MG; Bernal Quiros M; Wu Y-Y; Martinez-Garcia B; Kozyrev SV; Frostegard J; Truedsson L; de Ramon E; Gonzalez-Escribano MF; Ortego-Centeno N; Pons-Estel BA; D'Alfonso S; Sebastiani GD; Witte T; Lauwerys BR; Endreffy E; Kovacs L; Vasconcelos C; da Silva BM; Wren JD; Martin J; Castillejo-Lopez C; Alarcon-Riquelme ME
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(6):1960-1969

Evaluation of TRAF6 in a large multiancestral lupus cohort

Namjou B; Choi C-B; Harley ITW; Alarcon-Riquelme ME; Kelly JA; Glenn SB; Ojwang JO; Adler A; Kim K; Gallant CJ; Boackle SA; Criswell LA; Kimberly RP; Brown EE; Edberg J; Alarcon GS; Stevens AM; Jacob CO; Gilkeson GS; Kamen DL; Tsao BP; Anaya J-M; Kim E-M; Park S-Y; Sung Y-K; Guthridge JM; Merrill JT; Petri M; Ramsey-Goldman R; Vila LM; Niewold TB; Martin J; Pons-Estel BA; Vyse TJ; Freedman BI; Moser KL; Gaffney PM; Williams AH; Comeau ME; Reveille JD; Kang C; James JA; Scofield RH; Langefeld CD; Kaufman KM; Harley JB; Bae S-C
Article: JOURNAL OF RHEUMATOLOGY. 2012;39(6):1146-1154

Carotid Atherosclerosis, Disease Measures, Oxidized Low-density Lipoproteins, and Atheroprotective Natural Antibodies for Cardiovascular Disease in Early Rheumatoid Arthritis - An Inception Cohort Study

Ajeganova S; de Faire U; Jogestrand T; Frostegard J; Hafstroem I
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(5):694-699

Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus

Hughes T; Adler A; Merrill JT; Kelly JA; Kaufman KM; Williams A; Langefeld CD; Gilkeson GS; Sanchez E; Martin J; Boackle SA; Stevens AM; Alarcon GS; Niewold TB; Brown EE; Kimberly RP; Edberg JC; Ramsey-Goldman R; Petri M; Reveille JD; Criswell LA; Vila LM; Jacob CO; Gaffney PM; Moser KL; Vyse TJ; Alarcon-Riquelme ME; James JA; Tsao BP; Scofield RH; Harley JB; Richardson BC; Sawalha AH
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;90(4):648-660

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study

Lessard CJ; Adrianto I; Ice JA; Wiley GB; Kelly JA; Glenn SB; Adler AJ; Li H; Rasmussen A; Williams AH; Ziegler J; Comeau ME; Marion M; Wakeland BE; Liang C; Ramos PS; Grundahl KM; Gallant CJ; Alarcon-Riquelme ME; Alarcon GS; Anaya J-M; Bae S-C; Boackle SA; Brown EE; Chang D-M; Cho S-K; Criswell LA; Edberg JC; Freedman BI; Gilkeson GS; Jacob CO; James JA; Kamen DL; Kimberly RP; Kim J-H; Martin J; Merrill JT; Niewold TB; Park S-Y; Petri MA; Pons-Estel BA; Ramsey-Goldman R; Reveille JD; Scofield RH; Song YW; Stevens AM; Tsao BP; Vila LM; Vyse TJ; Yu C-Y; Guthridge JM; Kaufman KM; Harley JB; Wakeland EK; Langefeld CD; Gaffney PM; Montgomery CG; Moser KL
Article: GENES AND IMMUNITY. 2012;13(3):232-238

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis

Lin CP; Adrianto I; Lessard CJ; Kelly JA; Kaufman KM; Guthridge JM; Freedman BI; Anaya J-M; Alarcon-Riquelme ME; Pons-Estel BA; Martin J; Glenn S; Adler A; Bae S-C; Park S-Y; Bang S-Y; Song Y-W; Boackle SA; Brown EE; Edberg JC; Alarcon GS; Petri MA; Criswell LA; Ramsey-Goldman R; Reveille JD; Vila LM; Gilkeson GS; Kamen DL; Ziegler J; Jacob CO; Rasmussen A; James JA; Kimberly RP; Merrill JT; Niewold TB; Scofield RH; Stevens AM; Tsao BP; Vyse TJ; Langefeld CD; Moser KL; Harley JB; Gaffney PM; Montgomery CG
Article: GENES AND IMMUNITY. 2012;13(3):268-274

Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene

Lofgren SE; Frostegard J; Truedsson L; Pons-Estel BA; D'Alfonso S; Witte T; Lauwerys BR; Endreffy E; Kovacs L; Vasconcelos C; Martins da Silva B; Kozyrev SV; Alarcon-Riquelme ME
Article: ARTHRITIS & RHEUMATOLOGY. 2012;64(2):485-492

Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus

Hughes T; Adler A; Kelly JA; Kaufman KM; Williams AH; Langefeld CD; Brown EE; Alarcon GS; Kimberly RP; Edberg JC; Ramsey-Goldman R; Petri M; Boackle SA; Stevens AM; Reveille JD; Sanchez E; Martin J; Niewold TB; Vila LM; Scofield RH; Gilkeson GS; Gaffney PM; Criswell LA; Moser KL; Merrill JT; Jacob CO; Tsao BP; James JA; Vyse TJ; Alarcon-Riquelme ME; Harley JB; Richardson BC; Sawalha AH
Article: RESULTS IN IMMUNOLOGY. 2012;2:13-18

IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with other auto-antibodies against modified LDL.

Fiskesund R; Su J; Bulatovic I; Vikström M; de Faire U; Frostegård J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(1):136-142

Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK

Castillejo-Lopez C; Delgado-Vega AM; Wojcik J; Kozyrev SV; Thavathiru E; Wu Y-Y; Sanchez E; Pollmann D; Lopez-Egido JR; Fineschi S; Dominguez N; Lu R; James JA; Merrill JT; Kelly JA; Kaufman KM; Moser KL; Gilkeson G; Frostegard J; Pons-Estel BA; D'Alfonso S; Witte T; Luis Callejas J; Harley JB; Gaffney PM; Martin J; Guthridge JM; Alarcon-Riquelme ME
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2011;29(6):942-950

Effect of biological therapy on levels of atheroprotective antibodies against phosphorylcholine and apolipoproteins in rheumatoid arthritis: a one-year study

Ajeganova S; Fiskesund R; de Faire U; Hafstrom I; Frostegard J
Article: RHEUMATOLOGY. 2011;50(10):1785-1793

Longitudinal levels of apolipoproteins and antibodies against phosphorylcholine are independently associated with carotid artery atherosclerosis 5 years after rheumatoid arthritis onset-a prospective cohort study

Ajeganova S; Ehrnfelt C; Alizadeh R; Rohani M; Jogestrand T; Hafstrom I; Frostegard J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(10):1752-1757

Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus

Sanchez E; Nadig A; Richardson BC; Freedman BI; Kaufman KM; Kelly JA; Niewold TB; Kamen DL; Gilkeson GS; Ziegler JT; Langefeld CD; Alarcon GS; Edberg JC; Ramsey-Goldman R; Petri M; Brown EE; Kimberly RP; Reveille JD; Vila LM; Merrill JT; Anaya J-M; James JA; Pons-Estel BA; Martin J; Park S-Y; Bang S-Y; Bae S-C; Moser KL; Vyse TJ; Criswell LA; Gaffney PM; Tsao BP; Jacob CO; Harley JB; Alarcon-Riquelme ME; Sawalha AH
Article: ATHEROSCLEROSIS. 2011;218(1):117-122

Genetic and environmental regulation of inflammatory CVD biomarkers Lp-PLA₂ and IgM anti-PC

Rahman I; Atout R; Pedersen NL; de Faire U; Frostegard J; Ninio E; Bennet AM; Magnusson PKE
Article: ARTHRITIS & RHEUMATOLOGY. 2011;63(9):2755-2763

Association of PPP2CA Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Multiple Ethnic Groups

Tan W; Sunahori K; Zhao J; Deng Y; Kaufman KM; Kelly JA; Langefeld CD; Williams AH; Comeau ME; Ziegler JT; Marion MC; Bae S-C; Lee JH; Lee J-S; Chang D-M; Song YW; Yu C-Y; Kimberly RP; Edberg JC; Brown EE; Petri MA; Ramsey-Goldman R; Vila LM; Reveille JD; Alarcon-Riquelme ME; Harley JB; Boackle SA; Stevens AM; Scofield RH; Merrill JT; Freedman BI; Anaya J-M; Criswell LA; Jacob CO; Vyse TJ; Niewold TB; Gaffney PM; Moser KL; Gilkeson GS; Kamen DL; James JA; Grossman JM; Hahn BH; Tsokos GC; Tsao BP
Article: ARTHRITIS & RHEUMATOLOGY. 2011;63(6):1689-1697

Fine-Mapping and Transethnic Genotyping Establish IL2/IL21 Genetic Association With Lupus and Localize This Genetic Effect to IL21

Hughes T; Kim-Howard X; Kelly JA; Kaufman KM; Langefeld CD; Ziegler J; Sanchez E; Kimberly RP; Edberg JC; Ramsey-Goldman R; Petri M; Reveille JD; Martin J; Brown EE; Vila LM; Alarcon GS; James JA; Gilkeson GS; Moser KL; Gaffney PM; Merrill JT; Vyse TJ; Alarcon-Riquelme ME; Nath SK; Harley JB; Sawalha AH
Article: GENES AND IMMUNITY. 2011;12(4):270-279

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

Namjou B; Kothari PH; Kelly JA; Glenn SB; Ojwang JO; Adler A; Alarcon-Riquelme ME; Gallant CJ; Boackle SA; Criswell LA; Kimberly RP; Brown E; Edberg J; Stevens AM; Jacob CO; Tsao BP; Gilkeson GS; Kamen DL; Merrill JT; Petri M; Goldman RR; Vila LM; Anaya J-M; Niewold TB; Martin J; Pons-Estel BA; Sabio JM; Callejas JL; Vyse TJ; Bae S-C; Perrino FW; Freedman BI; Scofield RH; Moser KL; Gaffney PM; James JA; Langefeld CD; Kaufman KM; Harley JB; Atkinson JP
Article: PLOS GENETICS. 2011;7(5):e1002079

Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

Zhao J; Wu H; Khosravi M; Cui H; Qian X; Kelly JA; Kaufman KM; Langefeld CD; Williams AH; Comeau ME; Ziegler JT; Marion MC; Adler A; Glenn SB; Alarcon-Riquelme ME; Pons-Estel BA; Harley JB; Bae S-C; Bang S-Y; Cho S-K; Jacob CO; Vyse TJ; Niewold TB; Gaffney PM; Moser KL; Kimberly RP; Edberg JC; Brown EE; Alarcon GS; Petri MA; Ramsey-Goldman R; Vila LM; Reveille JD; James JA; Gilkeson GS; Kamen DL; Freedman BI; Anaya J-M; Merrill JT; Criswell LA; Scofield RH; Stevens AM; Guthridge JM; Chang D-M; Song YW; Park JA; Lee EY; Boackle SA; Grossman JM; Hahn BH; Goodship THJ; Cantor RM; Yu C-Y; Shen N; Tsao BP
Article: NATURE GENETICS. 2011;43(3):253-258

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Adrianto I; Wen F; Templeton A; Wiley G; King JB; Lessard CJ; Bates JS; Hu Y; Kelly JA; Kaufman KM; Guthridge JM; Alarcon-Riquelme ME; Anaya J-M; Bae S-C; Bang S-Y; Boackle SA; Brown EE; Petri MA; Gallant C; Ramsey-Goldman R; Reveille JD; Vila LM; Criswell LA; Edberg JC; Freedman BI; Gregersen PK; Gilkeson GS; Jacob CO; James JA; Kamen DL; Kimberly RP; Martin J; Merrill JT; Niewold TB; Park S-Y; Pons-Estel BA; Scofield RH; Stevens AM; Tsao BP; Vyse TJ; Langefeld CD; Harley JB; Moser KL; Webb CF; Humphrey MB; Montgomery CG; Gaffney PM
Article: BMC MUSCULOSKELETAL DISORDERS. 2011;12:13

Low level of physical activity in women with rheumatoid arthritis is associated with cardiovascular risk factors but not with body fat mass - a cross sectional study

Elkan A-C; Hakansson N; Frostegard J; Hafstrom I
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2011;88(1):83-91

Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study

Lessard CJ; Adrianto I; Kelly JA; Kaufman KM; Grundahl KM; Adler A; Williams AH; Gallant CJ; Alarcon-Riquelme ME; Anaya J-M; Bae S-C; Boackle SA; Brown EE; Chang D-M; Criswell LA; Edberg JC; Freedman BI; Gregersen PK; Gilkeson GS; Jacob CO; James JA; Kamen DL; Kimberly RP; Martin J; Merrill JT; Niewold TB; Park S-Y; Petri MA; Pons-Estel BA; Ramsey-Goldman R; Reveille JD; Song YW; Stevens AM; Tsao BP; Vila LM; Vyse TJ; Yu C-Y; Guthridge JM; Bruner GR; Langefeld CD; Montgomery C; Harley JB; Scofield RH; Gaffney PM; Moser KL
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2011;31(1):95-101

Annexin A5 Therapy Attenuates Vascular Inflammation and Remodeling and Improves Endothelial Function in Mice

Ewing MM; de Vries MR; Nordzell M; Pettersson K; de Boer HC; van Zonneveld AJ; Frostegard J; Jukema JW; Quax PHA
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(11):3404-3414

A 3′-Untranslated Region Variant Is Associated With Impaired Expression of CD226 in T and Natural Killer T Cells and Is Associated With Susceptibility to Systemic Lupus Erythematosus

Lofgren SE; Delgado-Vega AM; Gallant CJ; Sanchez E; Frostegard J; Truedsson L; de Ramon Garrido E; Sabio JM; Gonzalez-Escribano MF; Pons-Estel BA; D'Alfonso S; Witte T; Lauwerys BR; Endreffy E; Kovacs L; Vasconcelos C; da Silva BM; Martin J; Alarcon-Riquelme ME; Kozyrev SV
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2010;39(6):447-453

Anti-apoA-1 IgG and oxidized LDL are raised in rheumatoid arthritis (RA): potential associations with cardiovascular disease and RA disease activity

Vuilleumier N; Bratt J; Alizadeh R; Jogestrand T; Hafstrom I; Frostegard J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2010;21(2):577-584

Low Levels of Antibodies Against Phosphorylcholine in Alzheimer's Disease

Eriksson UK; Sjoberg BG; Bennet AM; de Faire U; Pedersen NL; Frostegard J
Article: STROKE. 2010;41(4):607-612

Low Levels of Antibodies Against Phosphorylcholine Predict Development of Stroke in a Population-Based Study From Northern Sweden

Fiskesund R; Stegmayr B; Hallmans G; Vikstrom M; Weinehall L; de Faire U; Frostegard J
Article: JOURNAL OF AUTOIMMUNITY. 2010;34(2):73-79

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: Effects on uptake of oxidized LDL in macrophages as a potential mechanism

de Faire U; Su J; Hua X; Frostegard A; Halldin M; Hellenius M-L; Wikstrom M; Dahlbom I; Gronlund H; Frostegard J
Article: ARTHRITIS RESEARCH & THERAPY. 2010;12(6):R214

Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus erythematosus

Anania C; Gustafsson T; Hua X; Su J; Vikstrom M; de Faire U; Heimburger M; Jogestrand T; Frostegard J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2010;39(1):77-83

Effects of anti-cardiolipin antibodies and IVIg on annexin A5 binding to endothelial cells: implications for cardiovascular disease

Frostegard AG; Su J; von Landenberg P; Frostegard J
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2009;24(11):3454-3460

Low levels of IgM antibodies against phosphorylcholine-A increase mortality risk in patients undergoing haemodialysis

Carrero JJ; Hua X; Stenvinkel P; Qureshi AR; Heimburger O; Barany P; Lindholm B; Frostegard J
Article: GENES AND IMMUNITY. 2009;10(5):397-403

Genetic associations of LYN with systemic lupus erythematosus

Lu R; Vidal GS; Kelly JA; Delgado-Vega AM; Howard XK; Macwana SR; Dominguez N; Klein W; Burrell C; Harley IT; Kaufman KM; Bruner GR; Moser KL; Gaffney PM; Gilkeson GS; Wakeland EK; Li Q-Z; Langefeld CD; Marion MC; Divers J; Alarcon GS; Brown EE; Kimberly RP; Edberg JC; Ramsey-Goldman R; Reveille JD; McGwin GJ; Vila LM; Petri MA; Bae S-C; Cho S-K; Bang S-Y; Kim I; Choi C-B; Martin J; Vyse TJ; Merrill JT; Harley JB; Alarcon-Riquelme ME; Nath SK; James JA; Guthridge JM
Article: JOURNAL OF CARDIOVASCULAR RISK. 2009;16(3):382-386

Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden

Gronlund H; Hallmans G; Jansson JH; Boman K; Wikstrom M; de Faire U; Frostegard J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2009;38(3):184-189

Dyslipidaemia and lipoprotein pattern in systemic lupus erythematosus (SLE) and SLE-related cardiovascular disease

Hua X; Su J; Svenungsson E; Hurt-Camejo E; Jensen-Urstad K; Angelin B; Bvenholm P; Frostegrd J
Article: ATHEROSCLEROSIS. 2009;203(2):528-532

Low levels of IgM antibodies against phosphorylcholine-A potential risk marker for ischemic stroke in men

Sjoberg BG; Su J; Dahlbom I; Gronlund H; Wikstrom M; Hedblad B; Berglund G; de Faire U; Frostegard J
Article: ARTHRITIS RESEARCH & THERAPY. 2009;11(2):R37

Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study

Elkan A-C; Hakansson N; Frostegard J; Cederholm T; Hafstrom I
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2008;37(5):352-359

Endothelial function and markers of endothelial activation in relation to cardiovascular disease in systemic lupus erythematosus

Svenungsson E; Cederholm A; Jensen-Urstad K; Fei G-Z; de Faire U; Frostegard J
Article: RHEUMATOLOGY. 2008;47(8):1144-1150

Natural antibodies against phosphorylcholine as potential protective factors in SLE

Su J; Hua X; Concha H; Svenungsson E; Cederholm A; Frostegard J
Article: CLINICAL SCIENCE. 2008;115(1-2):25-33

Anti-(apolipoprotein A-1) IgGs are associated with high levels of oxidized low-density lipoprotein in acute coronary syndrome

Vuilleumier N; Charbonney E; Fontao L; Alvarez M; Turck N; Sanchez J-C; Burkhard PR; Mensi N; Righini M; Reber G; James R; Mach F; Chevrolet J-C; Dayer J-M; Frostegard J; Roux-Lombard P
Article: ARTHRITIS RESEARCH & THERAPY. 2008;10(2):R34

Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis:: a randomized study

Elkan A-C; Sjoberg B; Kolsrud B; Ringertz B; Hafstrom I; Frostegard J
Article: JOURNAL OF RHEUMATOLOGY. 2007;34(9):1810-1816

Effects of low-dose prednisolone on endothelial function, atherosclerosis, and traditional risk factors for atherosclerosis in patients with rheumatoid arthritis -: A randomized study

Hafstrom I; Rohani M; Deneberg S; Wornert M; Jogestrand T; Frostegard J
Article: DRUG NEWS AND PERSPECTIVES. 2007;20(5):321-326

Annexin a5 multitasking: A potentially novel antiatherothrombotic agent?

Cederhohn A; Frostegard J
Article: NUTRITION & METABOLISM. 2007;4:7

Atheroprotective natural anti-phosphorylcholine antibodies of IgM subclass are decreased in Swedish controls as compared to non-westernized individuals from New Guinea

Frostegard J; Tao W; Georgiades A; Rastam L; Lindblad U; Lindeberg S
Article: NUTRITION & METABOLISM. 2006;3:39

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs

Jonsson T; Ahren B; Pacini G; Sundler F; Wierup N; Steen S; Sjoberg T; Ugander M; Frostegard J; Goransson L; Lindeberg S
Article: ATHEROSCLEROSIS. 2006;188(1):160-166

Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension

Su J; Georgiades A; Wu R; Thulin T; de Faire U; Frostegard J
Article: ATHEROSCLEROSIS. 2006;187(2):408-414

Association of TNF-α serum levels and TNFA promoter polymorphisms with risk of myocardial infarction

Bennet AM; van Maarle MC; Hallqvist J; Morgenstern R; Frostegard J; Wiman B; Prince JA; de Faire U
Article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 2006;38(3):297-306

Systemic lupus-erythematosus:: Deoxyribonuclease 1 in necrotic chromatin disposal

Napirei M; Gültekin A; Kloeckl T; Möröy T; Frostegård J; Mannherz HG
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2006;4(1):77-82

Treatment with combined oral contraceptives induces a rise in serum C-reactive protein in the absence of a general inflammatory response

van Rooijen M; Hansson LO; Frostegård J; Silveira A; Hamsten A; Bremme K
Article: LAKARTIDNINGEN. 2005;102(22):1752-1753

[Non-therapeutic ventilation , organ transplantation and medical ethics].

Frostegård J
Article: ARTHRITIS & RHEUMATOLOGY. 2005;52(1):192-200

Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations

Frostegård J; Svenungsson E; Wu RH; Gunnarsson I; Lundberg IE; Klareskog L; Hörkko S; Witztum JL
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(1):198-203

Decreased binding of annexin V to endothelial cells -: A potential mechanism in atherothrombosis of patients with systemic lupus erythematosus

Cederholm A; Svenungsson E; Jensen-Urstad K; Trollmo C; Ulfgren AK; Swedenborg J; Fei GZ; Frostegård J
Article: ATHEROSCLEROSIS. 2004;177(2):409-414

The A-1087IL-10 allele is associated with cardiovascular disease in SLE

Fei GZ; Svenungsson E; Frostegård J; Padyukov L
Article: ARTHRITIS & RHEUMATOLOGY. 2004;50(9):2869-2876

Platelet-activating factor-acetylhydrolase and other novel risk and protective factors for cardiovascular disease in systemic lupus erythematosus

Cederholm A; Svenungsson E; Stengel D; Fei GZ; Pockley AG; Ninio E; Frostegård J
Article: EUROPEAN HEART JOURNAL. 2004;25(16):1447-1453

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction

Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan ZQ
Article: LAKARTIDNINGEN. 2004;101(25):2190-2193

[The new biology. Truth, social construction or something in between?].

Frostegård J
Article: LAKARTIDNINGEN. 2004;101(19):1678-1679

[Immunization--future cure against atherosclerosis?].

Frostegård J
Article: LAKARTIDNINGEN. 2004;101(3):229

[Organ donation and utilitarianism: medical ethics more important than medical efficiency].

Frostegård J
Article: ATHEROSCLEROSIS. 2003;171(2):359-367

Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction

Bennet AM; Prince JA; Fei GZ; Lyrenäs L; Huang YH; Wiman B; Frostegård J; de Faire U
Article: EUROPEAN HEART JOURNAL. 2003;24(23):2099-2107

Risk factors for cardiovascular disease in patients with periodontitis

Buhlin K; Gustafsson A; Pockley AG; Frostegård J; Klinge B
Article: CLINICAL SCIENCE. 2003;105(5):615-620

Circulating oxidized low-density lipoprotein is increased in hypertension

Frostegård J; Wu RH; Lemne C; Thulin T; Witztum JL; De Faire U
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;106(1):143-148

Induction of IL-4 by platelet-activating factor

Huang YH; SchaferElinder L; Owman H; Lorentzen JC; Ronnelid J; Frostegard J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;103(1):61-66

Effects of in vitro hyperthermia on proliferative responses and lymphocyte activity

Huang YH; Haegerstrand A; Frostegard J
Article: HYPERTENSION. 2003;42(3):235-238

Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension

Pockley AG; Georgiades A; Thulin T; de Faire U; Frostegård J
Article: ARTHRITIS & RHEUMATOLOGY. 2003;48(9):2533-2540

Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor α/tumor necrosis factor receptor system in systemic lupus erythematosus

Svenungsson E; Gunnarsson I; Fei GZ; Lundberg IE; Klareskog L; Frostegård J
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2003;189(2):568-573

Antibodies against platelet-activating factor and platelet-activating factor-like lipids are raised in women with primary recurrent abortion

Frostegård J; Wramsby ML; Wu R; Bremme K
Article: ATHEROSCLEROSIS. 2003;169(1):77-85

Oxidised LDL modulates immune-activation by an IL-12 dependent mechanism

Fei GZ; Huang YH; Swedenborg J; Frostegård J
Article: LUPUS. 2003;12(6):454-461

TNF-α:: a link between hypertriglyceridaemia and inflammation in SLE patients with cardiovascular disease

Svenungsson E; Fei GZ; Jensen-Urstad K; de Faire U; Hamsten A; Frostegård J
Article: JOURNAL OF HYPERTENSION. 2002;20(9):1815-1820

Circulating heat shock protein and heat shock protein antibody levels in established hypertension

Pockley AG; de Faire U; Kiessling R; Lemne C; Thulin T; Frostegård J
Article: LAKARTIDNINGEN. 2002;99(34):3306-3308

[A case report: Myocardial infarction in a 26-year-old man with SLE. Acute coronary syndrome can occur in patients with SLE independently of gender and age].

Lehtihet M; Frostegård J
Article: LUPUS. 2002;11(11):744-752

Cardiac valvular abnormalities are frequent in systemic lupus erythematosus patients with manifest arterial disease

Jensen-Urstad K; Svenungsson E; de Faire U; Silveira A; Witztum JL; Hamsten A; Frostegård J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;116(2):326-331

Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism

Huang YH; Schäfer-Elinder L; Wu R; Claesson HE; Frostegård J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;115(3):561-566

Antibodies to adult human endothelial cells cross-react with oxidized low-density lipoprotein and β₂- glycoprotein I (β₂-GPI) in systemic lupus erythematosus

Wu R; Svenungsson E; Gunnarsson I; Haegerstrand-Gillis C; Andersson B; Lundberg I; Elinder LS; Frostegård J
Article: LAKARTIDNINGEN. 2001;98(42):4616-4619

[The debate on euthanasia with absurd conclusions].

Frostegård J
Article: CIRCULATION. 2001;104(16):1887-1893

Risk factors for cardiovascular disease in systemic lupus erythematosus

Svenungsson E; Jensen-Urstad K; Heimbürger M; Silveira A; Hamsten A; de Faire U; Witztum JL; Frostegård J
Article: LAKARTIDNINGEN. 2001;98(26-27):3135

[Immunological changes in hypertension and atherosclerosis].

Frostegård J
Article: HYPERTENSION. 2001;37(1):154-159

Antibodies to lysophosphatidylcholine are decreased in borderline hypertension

Wu RH; Lemne C; de Faire U; Frostegård J
Article: ATHEROSCLEROSIS. 2000;153(2):273-282

Induction of early atherosclerosis in CBA/J mice by combination of Trypanosoma cruzi infection and a high cholesterol diet

Sunnemark D; Harris RA; Frostegård J; Örn A
Article: HYPERTENSION. 2000;36(2):303-307

Circulating heat shock protein 60 is associated with early cardiovascular disease

Pockley AG; Wu R; Lemne C; Kiessling R; de Faire U; Frostegård J
Article: GENES AND IMMUNITY. 2000;1(6):380-385

Association analysis with microsatellite and SNP markers does not support the involvement of BCL-2 in systemic lupus erythematosus in Mexican and Swedish patients and their families

Johansson C; Castillejo-López C; Johanneson B; Svenungsson E; Gunnarsson I; Frostegård J; Sturfelt G; Truedsson L; Löfström B; Alcocer-Varela J; Lundberg I; Gyllensten UB; Alarcón-Segovia D; Alarcón-Riquelme ME
Article: JOURNAL OF INTERNAL MEDICINE. 1999;246(4):389-397

Antibodies to platelet-activating factor are associated with borderline hypertension, early atherosclerosis and the metabolic syndrome

Wu R; Lemne C; de Faire U; Frostegård J
Article: ATHEROSCLEROSIS. 1999;145(1):33-43

Cytokine expression in advanced human atherosclerotic plaques:: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

Frostegård J; Ulfgren AK; Nyberg P; Hedin U; Swedenborg J; Andersson U; Hansson GK
Article: HYPERTENSION. 1999;33(1):53-59

Autoantibodies to OxLDL are decreased in individuals with borderline hypertension

Wu RH; de Faire U; Lemne C; Witztum JL; Frostegård J
Article: LUPUS. 1999;8(2):142-150

Antibodies against lysophosphatidylcholine and oxidized LDL in patients with SLE

Wu R; Svenungsson E; Gunnarsson I; Andersson B; Lundberg I; Elinder LS; Frostegård J
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;48(5):480-484

Cellular and cytokine characterization of vascular inflammation in CBA/J mice chronically infected with Trypanosoma cruzi

Sunnemark D; Frostegård J; Örn A; Harris RA
Article: CIRCULATION. 1998;98(11):1092-1098

Antibodies to endothelial cells in borderline hypertension

Frostegård J; Wu RH; Gillis-Haegerstrand C; Lemne C; de Faire U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(4):626-630

Lysophosphatidylcholine is involved in the antigenicity of oxidized LDL

Wu RH; Huang YH; Elinder LS; Frostegård J
Article: JOURNAL OF INTERNAL MEDICINE. 1997;242(4):329-337

The influence of age on low density lipoprotein metabolism: effects of cholestyramine treatment in young and old healthy male subjects

Ericsson S; Berglund L; Frostegard J; Einarsson K; Angelin B
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):2257-2263

Expression of phospholipase A(2) isoforms in human normal and atherosclerotic arterial wall

Elinder LS; Dumitrescu A; Larsson P; Hedin U; Frostegard J; Claesson HE
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(5):963-968

Platelet-activating factor and oxidized LDL induce immune activation by a common mechanism

Frostegard J; Huang YH; Ronnelid J; SchaferElinder L
Article: HYPERTENSION. 1997;29(1):40-44

Association of serum antibodies to heat-shock protein 65 with borderline hypertension

Frostegard J; Lemne C; Andersson B; vanderZee R; Kiessling R; deFaire U
Article: LAKARTIDNINGEN. 1996;93(17):1603-1604

[Historical perspective of euthanasia. From Hippokrates to Nazi physicians].

Frostegård J
Article: ATHEROSCLEROSIS. 1996;121(1):93-103

Induction of heat shock protein in monocytic cells by oxidized low density lipoprotein

Frostegard J; Kjellman B; Gidlund M; Andersson B; Jindal S; Kiessling R
Article: FREE RADICAL RESEARCH. 1995;23(6):581-592

THE SUSCEPTIBILITY OF LOW-DENSITY-LIPOPROTEIN TO CHEMICAL OXIDATION IS CLOSELY-RELATED TO PRONENESS TO BIOLOGICAL MODIFICATION

FROSTEGARD J; REGNSTROM J; TORNVALL P; HAMSTEN A; NILSSON J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1995;15(10):1577-1583

OXIDIZED LDL INDUCES ENHANCED ANTIBODY-FORMATION AND MHC CLASS II-DEPENDENT IFN-GAMMA PRODUCTION IN LYMPHOCYTES FROM HEALTHY-INDIVIDUALS

HUANG YH; RONNELID J; FROSTEGARD J
Visa fler

Alla övriga publikationer

Editorial comment: JOURNAL OF LIPID RESEARCH. 2023;64(8):100412

Antibodies against oxidation-specific epitopes and risk of acute myocardial infarction

Frostegard J
Review: METABOLITES. 2023;13(6):720

Antibodies against Phosphorylcholine-Implications for Chronic Inflammatory Diseases

Frostegard J
Review: JOURNAL OF INTERNAL MEDICINE. 2023;293(1):48-62

Systemic lupus erythematosus and cardiovascular disease

Frostegard J
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2022;18(5):525-532

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

Frostegard J
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2022;18(1):67-74

The role of PCSK9 in inflammation, immunity, and autoimmune diseases

Frostegard J
Review: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2015;11(2):247-253

Prediction and management of cardiovascular outcomes in systemic lupus erythematosus

Frostegard J
Review: FRONTIERS IN ENDOCRINOLOGY. 2013;4:162

Immune mechanisms in atherosclerosis, especially in diabetes type 2.

Frostegård J
Review: LAKARTIDNINGEN. 2013;110(43-44):1931-1934

[The immune system in atherosclerosis. Immunomodulatory or anti-inflammatory treatment that is effective against atherosclerosis and its complications are needed to ensure the hypothesis].

Frostegård J
Review: BMC MEDICINE. 2013;11:117

Immunity, atherosclerosis and cardiovascular disease.

Frostegård J
Editorial comment: JOURNAL OF RHEUMATOLOGY. 2012;39(12):2233-2234

Atherosclerosis and Cardiovascular Disease in Rheumatoid Arthritis

Frostegard J
Review: CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY. 2012;42(2):154-163

Geographical Differences in Autoantibodies and Anti-infectious Agents Antibodies Among Healthy Adults

Shapira Y; Katz B-SP; Gilburd B; Barzilai O; Ram M; Blank M; Lindeberg S; Frostegard J; Anaya J-M; Bizzaro N; Jara LJ; Damoiseaux J; Shoenfeld Y; Levin NA
Review: ARTHRITIS RESEARCH & THERAPY. 2011;13(3):225

Cardiovascular co-morbidity in patients with rheumatic diseases

Frostegard J
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2010;30(5):892-893

Rheumatic Diseases Insights Into Inflammation and Atherosclerosis

Frostegard J
Corrigendum: GENES AND IMMUNITY. 2010;11(1):98

Genetic associations of LYN with systemic lupus erythematosus (vol 10, pg 397, 2009)

Lu R; Vidal GS; Kelly JA; Delgado-Vega AM; Howard XK; Macwana SR; Dominguez N; Klein W; Burrell C; Harley IT; Kaufman KM; Bruner GR; Moser KL; Gaffney PM; Gilkeson GS; Wakeland EK; Li Q-Z; Langefeld CD; Marion MC; Divers J; Alarcon GS; Brown EE; Kimberly RP; Edberg JC; Ramsey-Goldman R; Reveille JD; McGwin GJ; Vila LM; Petri MA; Bae S-C; Cho S-K; Bang S-Y; Kim I; Choi CB; Martin J; Vyse TJ; Merrill JT; Harley JB; Alarcon-Riquelme ME; Nath SK; James JA; Guthridge JM
Review: CLINICAL IMMUNOLOGY. 2010;134(1):47-54

Low level natural antibodies against phosphorylcholine: A novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

Frostegard J
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2009;1173:675-682

Antitreponemal Antibodies Leading to Autoantibody Production and Protection from Atherosclerosis in Kitavans from Papua New Guinea

Agmon-Levin N; Bat-sheva PK; Barzilai O; Ram M; Lindeberg S; Frostegard J; Shoenfeld Y
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2009;1173:292-300

Natural Antibodies against Phosphorylcholine in Cardiovascular Disease

de Faire U; Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):62

ANNEXIN A5 INHIBITS LYSOPHOSPHATIDYLCHOLINE INDUCED MMP-9 PRODUCTION; IMPLICATIONS FOR SLE AND CARDIOVASCULAR DISEASE

Domeij H; Modeer T; Gilburd B; Svenungsson E; Shoenfeld Y; Frostegard J
Published conference paper: LUPUS. 2008;17(5):364-367

Systemic lupus erythematosus and cardiovascular disease

Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):78

LOW LEVELS OF ANTIBODIES AGAINST PHOSPHORYLCHOLINE PREDICT DEVELOPMENT OF ATHEROSCLEROSIS

Frostegard J; Sjoberg B; Su J; Gronlund H; Dahlbom I; Hedblad B; Berglund G; de Faire U
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):78

IGM ANTIBODIES AGAINST PHOSPHOCHOLINE PROTECTION FACTORS FOR ATHEROSCLEROSIS IN PATIENTS WITH HYPERTENSION AND INHIBIT UPTAKE OF OXIDIZED LDL IN MACROPHAGES

Su J; Gronlund H; Cederholm A; Hua X; Georgiades A; Dahlbom I; de Faire U; Frostegard J
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2007;1108:96-103

Annexin A5 as a novel player in prevention of atherothrombosis in SLE and in the general population

Cederholm A; Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):29

Decreased annexin A5 binding to endothelium is associated with cardiovascular disease in systemic lupus erythematosus and inhibited by IVIG

Cederholm A; Von Landenberg P; Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):299

Dyslipidemia in SLE-related cardiovascular disease:: Paradoxical lipid pattern and antibodies against apo A1 and lipoprotein lipase

Hua X; Su J; Svenungsson E; Cederholm A; Frostegård J
Letter: JOURNAL OF INTERNAL MEDICINE. 2005;258(6):585-586

High iron stores and cardiovascular disease in systemic lupus erythematosus -: reply

Frostegård J
Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(9):1776-1785

Atherosclerosis in patients with autoimmune disorders

Frostegård J
Editorial comment: HEART. 2005;91(9):1124-1126

Heat shock proteins in cardiovascular disease and the prognostic value of heat shock protein related measurements

Pockley AG; Frostegård J
Review: JOURNAL OF INTERNAL MEDICINE. 2005;257(6):485-495

SLE, atherosclerosis and cardiovascular disease

Frostegård J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):90

Anti-HDL antibodies and lipoprotein characteristics in SLE-related cardiovascular disease

Su J; Cederholm A; Hurt-Camejo E; Svenungsson E; Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):65-66

Lipid-peroxidation is enhanced in sle patients and associated with arterial and renal disease manifestations

Frostegard J; Svenungsson E; Wu R; Gunnarsson I; Lundberg I; Klareskog L; Hörkkö S; Witztum J
Published conference paper: IMMUNOBIOLOGY. 2005;210(10):761-768

Annexin A5 in cardiovascular disease and systemic lupus erythematosus

Cederholm A; Frostegård J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:p148-S53

Endothelial function and activation in women with systemic lupus erythematosus

Svenungsson E; Cederholm A; Jensen-Urstad K; Fei G-Z; Frostegard J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:p143-S52

Decreased binding of annexin V to endothelial cells:: a novel mechanism of atherothrombosis in patients with systemic lupus erythematosus

Cederholm A; Svenungsson E; Jensen-Urstad K; Trollmo C; Ulfgren A-K; Swedenborg J; Fei G-Z; Frostegard J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:p122-S45

Non-traditional risk and protective factors for cardiovascular disease in systemic lupus erythematosus

Cederholm A; Svenungsson E; Stengel D; Fei G-Z; Pockley AG; Ninio E; Frostegard J
Meeting abstract: ARTHRITIS RESEARCH & THERAPY. 2005;7:S40

Anti-high-density lipoprotein antibodies and lipoprotein characteristics in systemic lupus erythematosus-related cardiovascular disease

Su J; Cederholm A; Hurt-Camejo E; Svenungsson E; Frostegard J
Letter: EUROPEAN HEART JOURNAL. 2004;25(15):1366

Cardiovascular disease, periodontitis and the monocyte relationship:: Reply

Buhlin K; Gustafsson A; Frostegård J; Klinge B; Pockley AG
Letter: HYPERTENSION. 2004;43(4):E18-E19

Response:: Is low-heat shock protein 70 a primary or a secondary event in the development of atherosclerosis?

Pockley AG; Georgiades A; Thulin T; de Faire U; Frostegård J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):317

TNF-alpha, dyslipoproteinemia and LDL oxidation are risk factors for CVD in SLE

Svenungsson E; Fei GZ; Gunnarsson I; Lundberg IE; Wu R; Witztum JL; Frostegard J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):315-316

Novel immunological risk factors for atherosclerosis

Frostegard J; Pockley AG; Georgiades A; Thulin T; Wu R; De Faire U
Review: AUTOIMMUNITY REVIEWS. 2002;1(4):233-237

Autoimmunity, oxidized LDL and cardiovascular disease.

Frostegård J
Review: LAKARTIDNINGEN. 1998;95(19):2203-2206

[Atherosclerosis not caused by overindulgence only. Infection may be a risk factor for cardiovascular disease].

Schäfer Elinder L; Frostegård J
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):283

Cytokine-stimulatory properties of phospholipids and oxidized LDL are mediated by the PAF receptor

Elinder LS; Huang YH; Frostegard J
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):284

Oxidised LDL induced T cell proliferation; LDL from patients with coronary artery disease inhibited the effect of oxidised LDL

Wu RH; Frostegard J; Giscombe R; Hamsten A; Holm G; Nilsson J; Lefvert AK
Visa fler

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Nyheter från KI

Kalenderhändelser från KI