Jennifer Lees

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Journal article: CIRCULATION. 2025;151(5):277-287
A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia
Ho FK; Mark PB; Lees JS; Pell JP; Strawbridge RJ; Kimenai DM; Mills NL; Woodward M; Mcmurray JJV; Sattar N; Welsh P
Journal article: CLINICAL KIDNEY JOURNAL. 2025;:sfaf003
Discordance between Cystatin C-based and Creatinine-based estimated glomerular filtration rate and health outcomes in adults: a systematic review and meta-analysis
Liu Q; Welsh P; Celis-Morales C; Ho FK; Lees JS; Mark PB
Journal article: BMJ OPEN. 2025;15(1):e093017
Effect of exercise on kidney-relevant biomarkers in the general population: a systematic review and meta-analysis.
Liu Q; Celis-Morales C; Lees J; Mark P; Welsh P
Journal article: AMERICAN JOURNAL OF KIDNEY DISEASES. 2024;84(6):731-741.e1
Sex and the Relationship Between Cardiometabolic Risk Factors and Estimated GFR Decline: A Population-Based Cohort Study.
Sullivan MK; Lees JS; Rosales BM; Cutting R; Wyld ML; Woodward M; Webster AC; Mark PB; De La Mata N
Journal article: CLINICAL KIDNEY JOURNAL. 2024;17(11):sfae313
Sodium zirconium cyclosilicate treatment and rates of emergency interventions for hyperkalaemia: a propensity-score weighted case-control study
Marshall WR; Curran GA; Traynor JP; Gillis KA; Mark PB; Lees JS
Journal article: DIABETES OBESITY & METABOLISM. 2024;26:43-54
Detecting and managing the patient with chronic kidney disease in primary care: A review of the latest guidelines
Mayne KJ; Hanlon P; Lees JS
Journal article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2024;:zwae352
Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20 656 patients with cardiovascular disease
Rochmawati ID; Deo S; Lees JS; Mark PB; Sattar N; Celis-Morales C; Pell JP; Welsh P; Ho FK
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(11):1799-1808
Sex differences in cancer outcomes across the range of eGFR
Shemilt R; Sullivan MK; Hanlon P; Jani BD; de la Mata N; Rosales B; Elyan BMP; Hedley JA; Cutting RB; Wyld M; Mcallister DA; Webster AC; Mark PB; Lees JS
Journal article: JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE. 2024;15(5):2046-2055
Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study
Liu Q; Celis-Morales C; Lees JS; Sattar N; Ho FK; Pell JP; Mark PB; Welsh P
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(10S):10.1681/asn.20244tz3pfym
Cancer Incidence and Outcomes in the Dialysis Population: Nationwide Registry Analysis of Time Trends and Outcomes
Elyan BMP; Nimmo A; Mark PB; Lees JS; Bell S
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(10S):10.1681/asn.2024tj99qmh6
Incidence of Cancer in People with CKD: A Systematic Review
Elyan BMP; Tan B; Lambourg E; Jones RJ; Mcallister DA; Lang NN; Mark PB; Lees JS; Bell S
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(10S):10.1681/asn.2024w8sh7fhq
Accuracy of Glomerular Filtration Rate Estimates among Patients with Cancer
Lees JS; Fu E; Faucon A-L; Elyan BMP; Inker LA; Levey AS; Mark PB; Carrero JJ
Journal article: TRANSPLANTATION. 2024;108(9S)
V-110.3: Understanding sex differences in relative cancer survival in kidney transplant recipients: A bi-national study, 1980-2019
Rosales B; Oliveras-Pages L; De La Mata N; Wyld M; Mark P; Sullivan M; Lees J; Webster A
Journal article: BJC REP. 2024;2(1):57
The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis.
Elyan BMP; Sullivan MK; Hedley J; De La Mata N; Webster AC; Venugopal B; Jones RJ; Lang NN; Mark PB; Lees JS
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(Supplement_1):gfae069-0148-841
#841 Healthcare workload amongst people with chronic kidney disease: what impact do mental disorders have?
Sullivan M; Langan-Martin J; Gallacher K; Elyan B; Webster A; Lees J; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(Supplement_1):gfae069-0566-970
#970 The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time
Elyan B; Hedley J; Sullivan M; De La Mata N; Webster A; Venugopal B; Jones R; Lang N; Mark P; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(Supplement_1):gfae069-0660-2246
#2246 Cardiovascular changes and outcomes across the early CKD spectrum: a UK Biobank cardiovascular MRI substudy
Stoumpos S; Gillon J; Lang N; Patel R; Mark P; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2024;39(Supplement_1):gfae069-0614-840
#840 Kidney cancer, treatment with nephrectomy and survival in chronic kidney disease (CKD)
Shemilt R; Elyan B; Sullivan M; Mark P; Lees J
Journal article: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION. 2024;33(3):337-343
Cystatin C should be routinely available for estimating kidney function.
Lees JS; Fabian J; Shlipak MG
Journal article: JACC: CARDIOONCOLOGY. 2024;6(2):267-279
Cardiovascular Eligibility Criteria and Adverse Event Reporting in Combined Immune Checkpoint and VEGF Inhibitor Trials.
Rankin S; Elyan B; Jones R; Venugopal B; Mark PB; Lees JS; Petrie MC; Lang NN
Journal article: KIDNEY MEDICINE. 2024;6(4):100796
Cystatin C- and Creatinine-based Estimated GFR Differences: Prevalence and Predictors in the UK Biobank.
Chen DC; Lu K; Scherzer R; Lees JS; Rutherford E; Mark PB; Potok OA; Rifkin DE; Ix JH; Shlipak MG; Estrella MM
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(3):335-346
The Improved Kidney Risk Score in ANCA-Associated Vasculitis for Clinical Practice and Trials
Bate S; McGovern D; Costigliolo F; Tan PG; Kratky V; Scott J; Chapman GB; Brown N; Floyd L; Brilland B; Martin-Nares E; Aydin MF; Ilyas D; Butt A; Riogh ENA; Kollar M; Lees JS; Yildiz A; Hinojosa-Azaola A; Dhaygude A; Roberts SA; Rosenberg A; Wiech T; Pusey CD; Jones RB; Jayne DRW; Bajema I; Jennette JC; Stevens KI; Augusto JF; Mejia-Vilet JM; Dhaun N; McAdoo SP; Tesar V; Little MA; Geetha D; Brix SR
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024;35(2):202-215
Effects of Empagliflozin on Fluid Overload, Weight, and Blood Pressure in CKD.
Mayne KJ; Staplin N; Keane DF; Wanner C; Brenner S; Cejka V; Stegbauer J; Judge PK; Preiss D; Emberson J; Trinca D; Dayanandan R; Lee R; Nolan J; Omata A; Green JB; Cherney DZI; Hooi LS; Pontremoli R; Tuttle KR; Lees JS; Mark PB; Davies SJ; Hauske SJ; Steubl D; Brückmann M; Landray MJ; Baigent C; Haynes R; Herrington WG; EMPA-KIDNEY Collaborative Group
Journal article: BMJ MEDICINE. 2024;3(1):e000732
Participant characteristics and exclusion from phase 3/4 industry funded trials of chronic medical conditions: meta-analysis of individual participant level data
Lees J; Crowther J; Hanlon P; Butterly EW; Wild SH; Mair F; Guthrie B; Gillies K; Dias S; Welton NJ; Katikireddi SV; Mcallister DA
Journal article: BRITISH JOURNAL OF CANCER. 2023;129(12):1968-1977
Personalised lung cancer risk stratification and lung cancer screening: do general practice electronic medical records have a role?
Jani BD; Sullivan MK; Hanlon P; Nicholl BI; Lees JS; Brown L; MacDonald S; Mark PB; Mair FS; Sullivan FM
Journal article: CLINICAL KIDNEY JOURNAL. 2023;16(12):2304-2308
Cardiovascular disease in older women with CKD
Radley A; Lees JS; Stevens KI
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2023;34(11S):1002
ANCA Renal Risk Score (ARRS) 2023: The Updated and Revised ARRS
Bate SG; Tan PG; Scott J; Chapman G; Brown N; Floyd L; Ilyas D; Martin-Nares E; Lees JS; Stevens KI; Brilland B; Augusto JF; Aydin MF; Hinojosa-Azaola A; Dhaygude AP; Wiech T; Bajema IM; Jayne DR; Jennette JC; Pusey CD; Dhaun N; Little MA; Tesar V; Geetha D; Brix SR
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2023;34(11S):373
Predictors of Differences in Cystatin C- and Creatinine-Based eGFR
Chen D; Lu K; Scherzer R; Potok OA; Lees JS; Mark P; Ix JH; Shlipak M; Estrella MM
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2023;34(11S):192-193
Rates of Emergency Temporary Central Venous Access and Emergency Haemodialysis in the Advent of Lokelma: A Retrospective Case Series in a Tertiary Renal Unit
Marshall W; Curran GA; Traynor JP; Mark PB; Lees JS
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2023;34(11S):321
eGFRcr, eGFRcys, Muscle Mass, and All-Cause Mortality in Kidney Transplant Recipients: Post-Hoc Analyses from a Randomized Controlled Trial
Curran GA; Mcneilly JD; Rankin AJ; Mayne KJ; Edy E; Mark PB; Lees JS
Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2023;330(13):1266-1277
Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes An Individual-Participant Data Meta-Analysis
Grams ME; Coresh J; Matsushita K; Ballew SH; Sang Y; Surapaneni A; de Pinho NA; Anderson A; Appel LJ; Arnlov J; Azizi F; Bansal N; Bell S; Bilo HJG; Brunskill NJ; Carrero JJ; Chadban S; Chalmers J; Chen J; Ciemins E; Cirillo M; Ebert N; Evans M; Ferreiro A; Fu EL; Fukagawa M; Green JA; Gutierrez OM; Herrington WG; Hwang S-J; Inker LA; Iseki K; Jafar T; Jassal SK; Jha V; Kadota A; Katz R; Koettgen A; Konta T; Kronenberg F; Lee BJ; Lees J; Levin A; Looker HC; Major R; Cohen CM; Mieno M; Miyazaki M; Moranne O; Muraki I; Naimark D; Nitsch D; Oh W; Pena M; Purnell TS; Sabanayagam C; Satoh M; Sawhney S; Schaeffner E; Schoettker B; Shen JI; Shlipak MG; Sinha S; Stengel B; Sumida K; Tonelli M; Valdivielso JM; van Zuilen AD; Visseren FLJ; Wang AY-M; Wen C-P; Wheeler DC; Yatsuya H; Yamagata K; Yang JW; Young A; Zhang H; Zhang L; Levey AS; Gansevoort RT
Journal article: NATURE REVIEWS NEPHROLOGY. 2023;19(10):625-626
GFR slope as a surrogate marker for future kidney failure
Lees JS; Mark PB
Journal article: EUROPEAN STROKE JOURNAL. 2023;8(3):756-768
Sex differences in associations between creatinine and cystatin C-based kidney function measures with stroke and major bleeding
Lees JS; De La Mata NL; Sullivan MK; Wyld ML; Rosales BM; Cutting R; Hedley JA; Rutherford E; Mark PB; Webster AC
Journal article: JOURNAL OF HUMAN HYPERTENSION. 2023;37(8):649-653
Sex and gender differences in the management of chronic kidney disease and hypertension
Mayne KJ; Sullivan MK; Lees JS
Journal article: KIDNEY INTERNATIONAL REPORTS. 2023;8(8):1648-1656
Outcomes in ANCA-Associated Vasculitis in Scotland: Validation of the Renal Risk Score in a Complete National Cohort.
McGovern DP; Lees JS; Traynor JP; Mackinnon B; Bell S; Hunter RW; Dhaun N; Metcalfe W; Kidder D; Lim M; Joss N; Kelly M; Taylor A; Cousland Z; Dey V; Buck K; Brix S; Geddes CC; McQuarrie EP; Stevens KI
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(8):1785-1788
Measure and risk: cystatin C, creatinine and controversy in CKD
Stevens KI; Lees JS
Journal article: KIDNEY MEDICINE. 2023;5(7):100672
Kidney Disease Patient Representation in Trials of Combination Therapy With VEGF-Signaling Pathway Inhibitors and Immune Checkpoint Inhibitors: A Systematic Review.
Elyan BMP; Rankin S; Jones R; Lang NN; Mark PB; Lees JS
Journal article: CLINICAL KIDNEY JOURNAL. 2023;16(7):1081-1091
Deprivation and chronic kidney disease-a review of the evidence
Grant CH; Salim E; Lees JS; Stevens KI
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(7):1666-1681
A systematic review and meta-analysis of the effect of intravitreal VEGF inhibitors on cardiorenal outcomes
Lees JS; Dobbin SJH; Elyan BMP; Gilmour DF; Tomlinson LP; Lang NN; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(Supplement_1):gfad063d_3880
#3880 REDUCED EGFR IS ASSOCIATED WITH IMPROVED SURVIVAL IN PATIENTS WITH RENAL CANCER WHO RECEIVED TARGETED SYSTEMIC ANTI-CANCER THERAPY
Elyan B; Jones R; Lang N; Mark P; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(Supplement_1):gfad063c_5476
#5476 SEX DIFFERENCES IN INCIDENT KIDNEY FAILURE AND THE IMPACT OF RISK FACTORS IN A POPULATION STUDY
Sullivan M; De La Mata N; Rosales B; Wyld M; Mark P; Webster A; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(Supplement_1):gfad063c_4727
#4727 FLOZINATION: A ROLLING QUALITY IMPROVEMENT PROGRAMME
Gillis K; Birch-Machin S; Russell C; Fairweather J; Spalding E; Lees J; Mcquarrie E; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(Supplement_1):gfad063c_3143
#3143 MEASURING CLINICAL JUDGEMENT IN PROSPECTIVE KIDNEY TRANSPLANT RECIPIENTS: A FEASIBILITY STUDY
Lees J; Jackson D; Sullivan M; Stevenson K; Stevens K; Hunter J; Park J; Norton W; Lever J; Mair F; Mcallister D
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(Supplement_1):gfad063c_5996
#5996 SEX DIFFERENCES IN THE DIAGNOSIS OF ADVANCED CANCER AND SUBSEQUENT OUTCOME IN PEOPLE WITH CKD
Shemilt R; Sullivan M; De La Mata N; Rosales B; Wyld M; Mark P; Webster A; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(6):1405-1407
Let's get physical: considering and overcoming the barriers to physical activity in CKD
Stevens KI; Graham-Brown M; Lees JS
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(5):1071-1079
The 'other' big complication: how chronic kidney disease impacts on cancer risks and outcomes
Lees JS; Elyan BMP; Herrmann SM; Lang NN; Jones RJ; Mark PB
Journal article: MEDICINE. 2023;51(3):190-195
Cardiovascular complications of chronic kidney disease
Mayne KJ; Lees JS; Mark PB
Journal article: CLINICAL KIDNEY JOURNAL. 2023;16(3):512-520
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios: associations with mortality in a haemodialysis cohort
Mayne KJ; Lees JS; Rutherford E; Thomson PC; Traynor JP; Dey V; Lang NN; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023;38(3):583-585
Bioimpedance in CKD: an untapped resource?
Mayne KJ; Lees JS; Herrington WG
Journal article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2023;12(3):e027079
Differential Associations of Cystatin C Versus Creatinine-Based Kidney Function With Risks of Cardiovascular Event and Mortality Among South Asian Individuals in the UK Biobank
Chen DC; Lees JS; Lu K; Scherzer R; Rutherford E; Mark PB; Kanaya AM; Shlipak MG; Estrella MM
Journal article: BRITISH JOURNAL OF GENERAL PRACTICE. 2023;73(727):E141-E147
Potential impact of NICE guidelines on referrals from primary care to nephrology: a primary care database and prospective research study
Sullivan MK; Jani BD; Rutherford E; Welsh P; McConnachie A; Major RW; McAllister D; Nitsch D; Mair FS; Mark PB; Lees JS
Journal article: TRIALS. 2022;23(1):1026
Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults-the TAKEOVER study.
Lithgow H; Johnston L; Ho FK; Celis-Morales C; Cobley J; Raastad T; Hunter AM; Lees JS; Mark PB; Quinn TJ; Gray SR
Journal article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2022;70(12):3660-3664
Age-adapted eGFR thresholds underestimate the risks beyond kidney failure associated with CKD in older populations
Lees JS; Shlipak MG
Journal article: JOURNAL OF CARDIAC FAILURE. 2022;28(11):1628-1641
Bioimpedance Indices of Fluid Overload and Cardiorenal Outcomes in Heart Failure and Chronic Kidney Disease: a Systematic Review
Mayne KJ; Shemilt R; Keane DF; Lees JS; Mark PB; Herrington WG
Journal article: JAMA NETWORK OPEN. 2022;5(10):e2238300
Assessment of Cystatin C Level for Risk Stratification in Adults With Chronic Kidney Disease
Lees JS; Rutherford E; Stevens KI; Chen DC; Scherzer R; Estrella MM; Sullivan MK; Ebert N; Mark PB; Shlipak MG
Journal article: AGE AND AGEING. 2022;51(Supplement_2):afac126.021
963 THE IMPACT OF AGE, SEX AND MORBIDITY COUNT ON EARLY TERMINATION: A META-ANALYSIS OF INDIVIDUAL PATIENT DATA FROM CLINICAL TRIALS
Lees JS; Hanlon P; Butterly E; Wild SH; Mair FS; Taylor RS; Guthrie B; Gillies K; Dias S; Welton N; McAllister DA
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(Supplement_3)
FC079: The Race-Free EGFR Equation, The Kidney Failure Risk Equation and Referrals to Specialist Renal Clinics
Sullivan M; Mark P; Mair F; Jani B; Nitsch D; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(Supplement_3)
FC077: Cystatin C Testing Improves Risk Stratification Associated with Chronic Kidney Disease Without Adopting Age-Adapted Diagnostic Thresholds: A UK Biobank Study
Lees J; Rutherford E; Stevens K; Chen D; Scherzer R; Estrella M; Sullivan M; Ebert N; Mark P; Shlipak M
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(Supplement_3):gfac114.003
FC079: The Race-Free EGFR Equation, The Kidney Failure Risk Equation and Referrals to Specialist Renal Clinics
Sullivan M; Mark P; Mair F; Jani B; Nitsch D; Lees J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(Supplement_3):gfac114.001
FC077: Cystatin C Testing Improves Risk Stratification Associated with Chronic Kidney Disease Without Adopting Age-Adapted Diagnostic Thresholds: A UK Biobank Study
Lees J; Rutherford E; Stevens K; Chen D; Scherzer R; Estrella M; Sullivan M; Ebert N; Mark P; Shlipak M
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(Supplement_3):gfac070.082
MO468: Moving More Associates With Reduced Risk of Cardiovascular Disease and Death Across All Stages of Chronic Kidney Disease: A UK Biobank Study
Stevens K; Delles C; Mark P; Thomson P; Gill J; Gray S; Ho F; Rutherford E; Lees J
Journal article: KIDNEY INTERNATIONAL. 2022;101(2):216-219
Insights into vitamin K metabolism in chronic kidney disease: more complicated than kale deficiency
Lees JS; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(2):271-284
Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: a prospective, multicentre cohort study
Sullivan MK; Lees JS; Drake TM; Docherty AB; Oates G; Hardwick HE; Russell CD; Merson L; Dunning J; Nguyen-Van-Tam JS; Openshaw P; Harrison EM; Baillie JK; Semple MG; Ho A; Mark PB
Journal article: BMJ MEDICINE. 2022;1(1):e000217
Effect of age, sex, and morbidity count on trial attrition: meta-analysis of individual participant level data from phase 3/4 industry funded clinical trials
Lees JS; Hanlon P; Butterly EW; Wild SH; Mair FS; Taylor RS; Guthrie B; Gillies K; Dias S; Welton NJ; McAllister DA
Journal article: AMERICAN JOURNAL OF TRANSPLANTATION. 2022;22(1):320-321
Vitamin K supplementation and vascular health after kidney transplantation: Authors' response
Lees JS; Mark PB
Journal article: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE. 2021;23(1):125
Myocardial changes on 3T cardiovascular magnetic resonance imaging in response to haemodialysis with fluid removal
Rankin AJ; Mangion K; Lees JS; Rutherford E; Gillis KA; Edy E; Dymock L; Treibel TA; Radjenovic A; Patel RK; Berry C; Roditi G; Mark PB
Article: CLINICAL KIDNEY JOURNAL. 2021;14(11):2409-2419
Multimorbidity and the risk of major adverse kidney events: findings from the UK Biobank cohort
Sullivan MK; Jani BD; Lees JS; Welsh CE; McConnachie A; Stanley B; Welsh P; Nicholl BI; Lyall DM; Carrero J-J; Nitsch D; Sattar N; Mair FS; Mark PB
Journal article: AMERICAN JOURNAL OF TRANSPLANTATION. 2021;21(10):3356-3368
The ViKTORIES trial: A randomized, double-blind, placebo-controlled trial of vitamin K supplementation to improve vascular health in kidney transplant recipients
Lees JS; Rankin AJ; Gillis KA; Zhu LY; Mangion K; Rutherford E; Roditi GH; Witham MD; Chantler D; Panarelli M; Jardine AG; Mark PB
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2021;32(10S):503
Predicting Outcomes in ANCA-Associated Vasculitis Using a Complete National Cohort
Mcgovern DP; Lees JS; Geddes CC; Mcquarrie E; Stevens KI
Journal article: CLINICAL KIDNEY JOURNAL. 2021;14(10):2187-2196
Global longitudinal strain by feature-tracking cardiovascular magnetic resonance imaging predicts mortality in patients with end-stage kidney disease
Rankin AJ; Zhu L; Mangion K; Rutherford E; Gillis KA; Lees JS; Woodward R; Patel RK; Berry C; Roditi G; Mark PB
Journal article: ECLINICALMEDICINE. 2021;38:101030
Kidney function and cancer risk: An analysis using creatinine and cystatin C in a cohort study
Lees JS; Ho F; Parra-Soto S; Celis-Morales C; Welsh P; Sullivan MK; Jani BD; Sattar N; Lang NN; Pell JP; Webster AC; Mark PB
Journal article: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION. 2021;30(4):430-436
Vitamin K and vascular calcification
Lees JS; Mark PB; Witham MD
Journal article: JOURNAL OF INFECTION. 2021;83(1):96-103
Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - A high risk community-hospital interface
Li KK; Woo YM; Stirrup O; Hughes J; Ho A; Filipe ADS; Johnson N; Smollett K; Mair D; Carmichael S; Tong L; Nichols J; Aranday-Cortes E; Brunker K; Parr YA; Nomikou K; McDonald SE; Niebel M; Asamaphan P; Sreenu VB; Robertson DL; Taggart A; Jesudason N; Shah R; Shepherd J; Singer J; Taylor AHM; Cousland Z; Price J; Lees JS; Jones TPW; Lopez CV; MacLean A; Starinskij I; Gunson R; Morris STW; Thomson PC; Geddes CC; Traynor JP; Breuer J; Thomson EC; Mark PB
Journal article: JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE. 2021;23(1):85
Cardiovascular magnetic resonance for the detection of descending thoracic aorta calcification in patients with end-stage renal disease
Edy E; Rankin AJ; Lees JS; Barrientos PH; Woodward R; Stoumpos S; Koktzoglou I; Edelman RR; Radjenovic A; Mark PB; Roditi GH
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(Supplement_1):gfab136.004
FC 065PREDICTING OUTCOMES IN ANCA ASSOCIATED VASCULITIS: THE COMPLETE SCOTTISH EXPERIENCE
McGovern D; Lees J; Kidder D; Smith J; Traynor J; Dhaun N; Hunter R; Joss N; Kelly M; MacKinnon M; Cousland Z; Shiell K; Lim M; Geddes CC; McQuarrie E; Stevens K
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(Supplement_1):gfab087.001
MO481KIDNEY FUNCTION MEASURES AND THE RISK OF CANCER INCIDENCE, CANCER DEATH AND ALL-CAUSE MORTALITY*
Lees J; Ho F; Parra-Soto S; Celis-Morales C; Welsh P; Sullivan M; Jani B; Sattar N; Pell J; Webster A; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(6):963-965
Fruit for thought: lifestyle interventions to reduce the risk of future chronic kidney disease
Lees JS; Mark PB
Journal article: NEPHROLOGY. 2021;26(4):328-332
Prolonged SARS-CoV-2 viral shedding in patients with chronic kidney disease
O'Sullivan ED; Lees JS; Howie KL; Pugh D; Gillis KA; Traynor JP; Macintyre I; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(1):39-41
Cystatin C to predict renal disease and cardiovascular risk
Lees JS; Mark PB
Journal article: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2020;31(10):2434-2445
Vitamin K Supplementation to Improve Vascular Stiffness in CKD: The K4Kidneys Randomized Controlled Trial
Witham MD; Lees JS; White M; Band M; Bell S; Chantler DJ; Ford I; Fulton RL; Kennedy G; Littleford RC; McCrea IV; McGlynn D; Panarelli M; Ralston MR; Rutherford E; Severn A; Thomson N; Traynor JP; Struthers AD; Wetherall K; Mark PB
Journal article: NATURE MEDICINE. 2020;26(8):1308
Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease (vol 25, pg 1753, 2019)
Lees JS; Welsh CE; Celis-Morales CA; Mackay D; Lewsey J; Gray SR; Lyall DM; Cleland JG; Gill JMR; Jhund PS; Pell J; Sattar N; Welsh P; Mark PB
Journal article: OPEN HEART. 2020;7(2):e001070
Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial
Lees JS; Mangion K; Rutherford E; Witham MD; Woodward R; Roditi G; Hopkins T; Brooksbank K; Jardine AG; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35(Supplement_3):gfaa142.p1852
P1852REGISTRATION WITH PATIENT-FACING ONLINE HEALTH RECORDS IN CHRONIC KIDNEY DISEASE IS ASSOCIATED WITH A LOWER INCIDENCE OF HYPERKALAEMIA
Mayne K; Rankin A; Lees J; Traynor J; Mark P; Gillis K
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2020;35(Supplement_3):gfaa140.mo011
MO011A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF VITAMIN K SUPPLEMENTATION TO IMPROVE VASCULAR HEALTH IN KIDNEY TRANSPLANT RECIPIENTS
Lees J; Rankin A; Gillis K; Zhu L; Rutherford E; Roditi G; Witham M; Jardine AG; Mark P
Journal article: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE. 2019;112(11):835-840
Proton pump inhibitor use and progression to major adverse renal events: a competing risk analysis
Grant CH; Gillis KA; Lees JS; Traynor JP; Mark PB; Stevens KI
Journal article: NATURE MEDICINE. 2019;25(11):1753-1760
Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease
Lees JS; Welsh CE; Celis-Morales CA; Mackay D; Lewsey J; Gray SR; Lyall DM; Cleland JG; Gill JMR; Jhund PS; Pell J; Sattar N; Welsh P; Mark PB
Journal article: BMC NEPHROLOGY. 2019;20(1):237
Obesity is not associated with progression to end stage renal disease in patients with biopsy-proven glomerular diseases
Elyan BMP; Lees JS; Gillis KA; Mackinnon B; Fox JG; Geddes CC; McQuarrie EP
Journal article: HEART. 2019;105(12):938-945
Vitamin K status, supplementation and vascular disease: a systematic review and meta-analysis
Lees JS; Chapman FA; Witham MD; Jardine AG; Mark PB
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34(Supplement_1):gfz106.fp778
FP778CORRELATION OF ARTERIAL STIFFNESS, CALCIFICATION AND LEFT VENTRICULAR MASS INDEX IN RENAL TRANSPLANT RECIPIENTS: BASELINE ASSESSMENTS FROM A CLINICAL TRIAL
Lees JS; Rankin AJ; Gillis K; Rutherford E; Roditi GH; Jardine A; Mark P
Journal article: TRANSPLANT INTERNATIONAL. 2019;32(2):153-162
Interaction between socioeconomic deprivation and likelihood of pre-emptive transplantation: influence of competing risks and referral characteristics - a retrospective study
Gillis KA; Lees JS; Ralston MR; Glen JA; Stevenson KS; McManus SK; Geddes CC; Clancy M; Traynor JP; Mark PB
Journal article: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE. 2019;112(1):23-27
The impact of coronary angiography on renal transplant function
Lees JS; Findlay MD; Mark PB; Geddes CC
Journal article: CLINICAL KIDNEY JOURNAL. 2018;11(5):605-609
Renal biopsy: it is time for pragmatism and consensus
Lees JS; McQuarrie EP; Mackinnon B
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2018;33(suppl_1):i440-i441
SP289FACTORS ASSOCIATED WITH VASCULAR CALCIFICATION IN CKD: BASELINE ASSESSMENTS FROM A CLINICAL TRIAL
Lees J; Ralston M; Traynor J; Witham M; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2018;33(suppl_1):i255
FP629THE ROLE OF SOCIOECONOMIC FACTORS IN THE CHOICE OF FIRST MODALITY OF RENAL REPLACEMENT THERAPY IN END STAGE KIDNEY DISEASE
Gillis K; Lees J; Ralston M; McManus S; Clancy M; Traynor J; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2018;33(suppl_1):i135
FP308OBESITY IS NOT ASSOCIATED WITH PROGRESSION TO END STAGE RENAL DISEASE IN PATIENTS WITH BIOPSY-PROVEN GLOMERULAR DISEASES
Elyan B; Lees J; McQuarrie E; Geddes C; MacKinnon B; Fox J
Journal article: REPRODUCTIVE BIOMEDICINE ONLINE. 2018;36(2):219-226
The utility of anti-Mullerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation
Stoumpos S; Lees J; Welsh P; Hund M; Geddes CC; Nelson SM; Mark PB
Journal article: CLINICAL KIDNEY JOURNAL. 2017;10(4):573-577
Risk factors for bleeding complications after nephrologist-performed native renal biopsy
Lees JS; McQuarrie EP; Mordi N; Geddes CC; Fox JG; Mackinnon B
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32(suppl_3):iii552-iii553
MP345PREDICTING MORTALITY BEFORE RENAL REPLACEMENT THERAPY IN CHRONIC KIDNEY DISEASE PATIENTS
Lees J; Gillis K; Jardine A; Mark P; Traynor J
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32(suppl_3):iii468-iii469
MP111MINERALOCORTICOID RECEPTOR ANTAGONISM IN CHRONIC KIDNEY DISEASE
Gillis K; Lees J; Jardine A; Traynor J; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32(suppl_3):iii130
SP077INVESTIGATING THE UTILITY OF ANTI-MULLERIAN HORMONE IN YOUNG WOMEN WITH CHRONIC KIDNEY DISEASE
Stoumpos S; Lees J; Welsh P; Geddes C; Nelson S; Mark P
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(suppl_1):i425-i426
MP257RISK FACTORS ASSOCIATED WITH BLEEDING COMPLICATIONS AFTER NATIVE RENAL BIOPSY
Lees JS; McQuarrie E; Mordi N; Fox J; Geddes C; MacKinnon B
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(suppl_1):i131-i132
SP138GLOMERULAR DISEASE IN OBESE PATIENTS: NOT ALWAYS FSGS
Lees J; Mackinnon B; Fox JG; Geddes CC; McQuarrie EP
Journal article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(suppl_1):i310
SP644THE IMPACT OF CORONARY ANGIOGRAPHY ON RENAL TRANSPLANT FUNCTION
Lees JS; Findlay M; Clouston J; Geddes C
Journal article: MEDICINE. 2015;43(8):469-473
Cardiovascular complications of chronic kidney disease
Lees JS; Mark PB; Jardine AG
Journal article: PLOS BIOLOGY. 2013;11(12):e1001738
Stem Cell Transplantation in Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis of Animal Studies
Antonic A; Sena ES; Lees JS; Wills TE; Skeers P; Batchelor PE; Macleod MR; Howells DW
Journal article: THE JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH. 2013;43(2):126-133
IgG4-related disease: a novel, important but easily missed condition
Lees JS; Church N; Langdale-Brown B; Bellamy C; Gibson P; Watson S
Journal article: INTERNATIONAL JOURNAL OF STROKE. 2012;7(7):582-588
Stem cell-based therapy for experimental stroke: A systematic review and meta-analysis
Lees JS; Sena ES; Egan KJ; Antonic A; Koblar SA; Howells DW; Macleod MR
Journal article: STROKE. 2011;42(9):2618-2621
Low Body Temperature Does Not Compromise the Treatment Effect of Alteplase
Lees JS; Mishra NK; Saini M; Lyden PD; Shuaib A
Journal article: STROKE. 2008;39(1):231-233
Time spent at home poststroke - "Home-Time" a meaningful and robust outcome measure for stroke trials
Quinn TJ; Dawson J; Lees JS; Chang T-P; Walters MR; Lees KR
Journal article: STROKE. 2007;38(6):1893-1898
Association between disability measures and healthcare costs after initial treatment for acute stroke
Dawson J; Lees JS; Chang T-P; Walters MR; Ali M; Davis SM; Diener H-C; Lees KR
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Preprint: MEDRXIV. 2023
Sex differences in the diagnosis of advanced cancer and subsequent outcome in people with chronic kidney disease: an analysis of a national population cohort
Shemilt R; Sullivan MK; Hanlon P; Jani B; De La Mata N; Rosales B; Elyan BMP; Wyld M; Hedley JA; Cutting R; McAllister DA; Webster AC; Mark PB; Lees JS
Preprint: MEDRXIV. 2023
Cardiovascular Eligibility Criteria and Adverse Event Reporting in Cancer Therapy Trials of Combined Immune Checkpoint and VEGF Inhibitors: A Systematic Review
Rankin S; Elyan B; Jones R; Venugopal B; Mark P; Lees J; Petrie M; Lang N
Preprint: MEDRXIV. 2023
Participant characteristics and exclusion from trials: a meta-analysis of individual participant-level data from phase 3/4 industry-funded trials in chronic medical conditions
Lees J; Crowther J; Hanlon P; Butterly E; Wild S; Mair F; Guthrie B; Gillies K; Dias S; Welton N; Katikireddi SV; McAllister D
Preprint: RESEARCH SQUARE. 2022
Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER study
Lithgow H; Johnston L; Ho F; Celis-Morales C; Cobley J; Raastad T; Hunter A; Lees J; Mark P; Quinn T; Gray S
Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37:I337
MOVING MORE ASSOCIATES WITH REDUCED RISK OF CARDIOVASCULAR DISEASE AND DEATH ACROSS ALL STAGES OF CHRONIC KIDNEY DISEASE: A UK BIOBANK STUDY
Stevens K; Delles C; Mark P; Thomson P; Gill J; Gray S; Ho F; Rutherford E; Lees J
Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37:I844-I845
THE RACE-FREE EGFR EQUATION, THE KIDNEY FAILURE RISK EQUATION AND REFERRALS TO SPECIALIST RENAL CLINICS
Sullivan M; Mark P; Mair F; Jani B; Nitsch D; Lees J
Conference publication: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37:I842-I843
CYSTATIN C TESTING IMPROVES RISK STRATIFICATION ASSOCIATED WITH CHRONIC KIDNEY DISEASE WITHOUT ADOPTING AGE-ADAPTED DIAGNOSTIC THRESHOLDS: A UK BIOBANK STUDY
Lees J; Rutherford E; Stevens K; Chen D; Scherzer R; Estrella M; Sullivan M; Ebert N; Mark P; Shlipak M
Preprint: MEDRXIV. 2021
Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - a high risk community-hospital interface
Li K; Woo M; Stirrup O; Hughes J; Ho A; Da Silva Filipe A; Johnson N; Smollett K; Mair D; Carmichael S; Tong L; Nichols J; Aranday-Cortes E; Brunker K; Parr Y; Nomikou K; McDonald S; Niebel M; Asamaphan P; Sreenu V; Robertson D; Taggart A; Jesudason N; Shah R; Shepherd J; Singer J; Taylor AHM; Cousland Z; Price J; Lees J; Jones TPW; Lopez CV; MacLean A; Starinskij I; Gunson R; Morris STW; Thomson P; Geddes C; Traynor J; Breuer J; The COVID-19 Genomics UK (COG-UK) consortium; Thomson E; Mark P

Forskningsbidrag

Kidney function as a complicator of cancer treatment
Wellcome Trust
29 July 2024 - 28 July 2029
Defining the bi-directional relationship between cancer and kidney disease
Chief Scientist Office
1 January 2020
Vitamin K in Transplanted kidney Organ Recipients: Investigating vEssel Stiffness (ViKTORIES)
Kidney Research UK
19 June 2017 - 18 August 2019

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