Jan-Inge Henter

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Läkarexamen vid Uppsala Universitet 1980 och AT i Uppsala län (1980-1981). Därefter specialistutbildning i pediatrik i Stockholm (1982-1987). Avhandling vid Karolinska Institutet 1990, med fokus på hemofagocyterande lymfohistiocytos (HLH).

Kliniskt subspecialiserad i barnhematologi/barnonkologi. Professor vid Karolinska Institutet 2004.

Forsknings- och utbildningsdirektör vid Karolinska Universitetssjukhuset 2012-2017.

UTBILDNING
1973-1980 Läkarutbildning, Uppsala Universitet
1976-1979 Ekonomlinjen (3-år, motsv civilekonom), Uppsala Universitet
1980-1981 Legitimerad läkare
1982-1987 Specialist i pediatrik
1986-1990 Dr Med Sci (Ph.D.), Dept of Pediatrics, Karolinska Institutet

AKADEMISKA PRISER OCH UTMÄRKELSER
2002: Barncancerfondens Jubileumspris
2003: Alvarengas pris (utdelat av Svenska Läkaresällskapet)
2011: Lennanders pris (utdelat av Svenska Läkaresällskapet)
2011: Svenska Läkaresällskapets Jubileumspris
2016: Cancer- och Allergifondens Miljömedicinska pris

Forskningsbeskrivning

Det huvudsakliga forskningsintresset är de histiocytära sjukdomarna, särskilt hemofagocyterande lymfohistiocytos (HLH) och Langerhans cellhistiocytos (LCH).

Har utvecklat de diagnostiska kriterierna för HLH och var principal investigator (PI) för de internationella kliniska studierna HLH-94 och HLH-2004. Har även studerat biologiska och genetiska defekter vid HLH. Ett annat intresse är olika sekundära former av HLH.

Beträffande LCH så driver vi kliniska och biologiska studier med det övergripande målet att reducera komplikationer och mortalitet.

Bland övriga forskningsområden kan nämnas andra blodsjukdomar, samt vård i livets slutskede.

President i Histiocyte Society 2004-2007, samt grundare och första president i föreningen the International Conference for Rare Diseases and Orphan Drugs (ICORD).

Artiklar

Article: BLOOD. 2024;143(10):872-881
Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation.
Böhm S; Wustrau K; Pachlopnik Schmid J; Prader S; Ahlmann M; Yacobovich J; Beier R; Speckmann C; Behnisch W; Ifversen M; Jordan M; Marsh R; Naumann-Bartsch N; Mauz-Körholz C; Hönig M; Schulz A; Malinowska I; Hines M; Nichols KE; Gil-Herrera J; Talano J-A; Crooks B; Formankova R; Jorch N; Bakhtiar S; Kühnle I; Streiter M; Nathrath M; Russo A; Dürken M; Lang P; Lindemans C; Henter J-I; Lehmberg K; Ehl S
Article: NATURE COMMUNICATIONS. 2024;15(1):1752
Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF
Kvedaraite E; Lourda M; Mouratidou N; Duking T; Padhi A; Moll K; Czarnewski P; Sinha I; Xagoraris I; Kokkinou E; Damdimopoulos A; Weigel W; Hartwig O; Santos TE; Soini T; Van Acker A; Rahkonen N; Tullberg MF; Ringqvist E; Buggert M; Jorns C; Lindforss U; Nordenvall C; Stamper CT; Unnersjoe-Jess D; Akber M; Nadisauskaite R; Jansson J; Vandamme N; Sorini C; Grundeken ME; Rolandsdotter H; Rassidakis G; Villablanca EJ; Idestroem M; Eulitz S; Arnell H; Mjoesberg J; Henter J-I; Svensson M
Article: BLOOD. 2024;143(3):233-242
Malignancy-associated hemophagocytic lymphohistiocytosis in Sweden: incidence, clinical characteristics, and survival
Lofstedt A; Jadersten M; Meeths M; Henter J-I
Journal article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2024;1448:525-551
Etoposide Therapy of Cytokine Storm Syndromes.
Henter J-I; von Bahr Greenwood T
Article: CANCER REPORTS. 2023;6(9):e1852
Longitudinal strain analysis for assessment of early cardiotoxicity during anthracycline treatment in childhood sarcoma: A single center experience
Alpman MS; Jarting A; Magnusson K; Manouras A; Henter J-I; Broberg AM; Herold N
Article: HAEMATOLOGICA. 2023;108(9):2422-2434
Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells
Hagey DW; Kvedaraite E; Akber M; Goergens A; Javadi J; Greenwood TVB; Bjorklund C; Akefeldt SO; Hannegard-Hamrin T; Arnell H; Dobra K; Herold N; Svensson M; El Andaloussi S; Henter J-I; Lourda M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2023;29(7):438.e1-438.e16
Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-Like Syndrome
Hines MR; Knight TE; McNerney KO; Leick MB; Jain T; Ahmed S; Frigault MJ; Hill JA; Jain MD; Johnson WT; Lin Y; Mahadeo KM; Maron GM; Marsh RA; Neelapu SS; Nikiforow S; Ombrello AK; Shah NN; Talleur AC; Turicek D; Vatsayan A; Wong SW; Maus MV; Komanduri KV; Berliner N; Henter J-I; Perales M-A; Frey NV; Teachey DT; Frank MJ; Shah NN
Article: CELL REPORTS MEDICINE. 2023;4(5):101038
The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis
Kokkinou E; Soini T; Pandey RV; van Acker A; Theorell J; Czarnewski P; Kvedaraite E; Vandamme N; Lourda M; Sorini C; Weigel W; Carrasco A; Tibbitt CA; Schlums H; Lindforss U; Nordenvall C; Ljunggren M; Idestrom M; Svensson M; Henter J-I; Villablanca EJ; Bryceson YT; Rolandsdotter H; Mjosberg J
Article: PLOS ONE. 2023;18(12):e0295838
Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial
Sunden-Cullberg J; Chen P; Habel H; Skorup P; Janols H; Rasmuson J; Niward K; Balkhed AO; Chatzidionysiou K; Asgeirsson H; Blennow O; Parke A; Svensson A-K; Muvva JR; Ljunggren H-G; Horne A-C; Aden U; Henter J-I; Sonnerborg A; Vesterbacka J; Nowak P; Lampa J
Article: SCIENCE IMMUNOLOGY. 2022;7(78):eadd3330
Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology
Kvedaraite E; Milne P; Khalilnezhad A; Chevrier M; Sethi R; Lee HK; Hagey DW; Greenwood TVB; Mouratidou N; Jadersten M; Lee NYS; Minnerup L; Tan Y; Dutertre C-A; Benac N; Hwang YY; Lum J; Loh AHP; Jansson J; Teng KWW; Khalilnezhad S; Xu W; Resteu A; Tey HL; Guan NL; Larbi A; Howland SW; Arnell H; Andaloussi SEL; Braier J; Rassidakis G; Galluzzo L; Dzionek A; Henter J-I; Chen J; Collin M; Ginhoux F
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(6):925-940
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial
Jadersten M; Lilienthal I; Tsesmetzis N; Lourda M; Bengtzen S; Bohlin A; Arnroth C; Erkers T; Seashore-Ludlow B; Giraud G; Barkhordar GS; Tao S; Fogelstrand L; Saft L; Ostling P; Schinazi RF; Kim B; Schaller T; Juliusson G; Deneberg S; Lehmann S; Rassidakis GZ; Hoglund M; Henter J-I; Herold N
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;198(4):721-728
Screening for neurodegeneration in Langerhans cell histiocytosis with neurofilament light in plasma
Sveijer M; Greenwood TVB; Jadersten M; Kvedaraite E; Zetterberg H; Blennow K; Lourda M; Gavhed D; Henter J-I
Article: FRONTIERS IN PEDIATRICS. 2022;10:872859
Plasma Signaling Factors in Patients With Langerhans Cell Histiocytosis (LCH) Correlate With Relative Frequencies of LCH Cells and T Cells Within Lesions
Mitchell J; Kvedaraite E; Greenwood TVB; Lourda M; Henter J-I; Berzins SP; Kannourakis G
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:850443
Simple Evaluation of Clinical Situation and Subtypes of Pediatric Hemophagocytic Lymphohistiocytosis by Cytokine Patterns
Xu X-J; Luo Z-B; Song H; Xu W-Q; Henter J-I; Zhao N; Wu M-H; Tang Y-M
Article: ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS. 2021;69(1):31
Molecular Genetics Diversity of Primary Hemophagocytic Lymphohistiocytosis among Polish Pediatric Patients
Babol-Pokora K; Wolowiec M; Popko K; Jaworowska A; Bryceson YT; Tesi B; Henter J-I; Mlynarski W; Badowska W; Balwierz W; Drabko K; Kalwak K; Maciejka-Kemblowska L; Pieczonka A; Sobol-Milejska G; Koltan S; Malinowska I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of in COVID-19
Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
Article: JOURNAL OF PEDIATRICS. 2021;237:65-70.e3
Additive Prognostic Impact of Gastrointestinal Involvement in Severe Multisystem Langerhans Cell Histiocytosis
Minkov M; Poetschger U; Thacker N; Astigarraga I; Braier J; Donadieu J; Henter J-I; Lehrnbecher T; Rodriguez-Galindo C; Sieni E; Nanduri V; van den Bos C; Abla O
Article: JOURNAL OF RHEUMATOLOGY. 2021;48(10):1596-1602
Efficacy of Moderately Dosed Etoposide in Macrophage Activation Syndrome-Hemophagocytic Lymphohistiocytosis
Horne A; Greenwood TVB; Chiang SCC; Meeths M; Bjorklund C; Ekelund M; Erensjo P; Berg S; Hagelberg S; Bryceson YT; Andersson U; Henter J-I
Article: EUROPEAN JOURNAL OF ANAESTHESIOLOGY. 2021;38(7):692-701
Clinical and laboratory signs of haemophagocytic lymphohistiocytosis associated with pandemic influenza A (H1N1) infection in patients needing extracorporeal membrane oxygenation A retrospective observational study
Greenwood TVB; Holzgraefe B; Chiang SCC; Wang Y; Tesi B; Bryceson YT; Henter J-I
Article: MOLECULAR MEDICINE. 2021;27(1):48
Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome
Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Andersson U
Article: ACTA PAEDIATRICA. 2021;110(4):1315-1321
Patients with both Langerhans cell histiocytosis and Crohn's disease highlight a common role of interleukin-23
Kvedaraite E; Lourda M; Han H; Tesi B; Mitchell J; Idestrom M; Mouratidou N; Rassidakis G; Greenwood TVB; Cohen-Aubart F; Jadersten M; Akefeldt SO; Svensson M; Kannourakis G; Bryceson YT; Haroche J; Henter J-I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2021;185(2):517-527
Chondrodysplasia and growth failure in children after early hematopoietic stem cell transplantation for non-oncologic disorders
Botto LD; Meeths M; Campos-Xavier B; Bergamaschi R; Mazzanti L; Scarano E; Finocchi A; Cancrini C; Zirn B; Kuehnle I; Kramm CM; Alanay Y; Jones WD; Irving M; Sabir A; Henter J-I; Borgstrom B; Nordgren A; Hammarsjo A; Putti C; Mozzato C; Zuccarello D; Nishimura G; Bonafe L; Grigelioniene G; Unger S; Superti-Furga A
Article: FRONTIERS IN ONCOLOGY. 2021;11:780191
Neutralizing Anti-IL-17A Antibody Demonstrates Preclinical Activity Enhanced by Vinblastine in Langerhans Cell Histiocytosis
Akefeldt SO; Ismail MB; Belot A; Salvatore G; Bissay N; Gavhed D; Arico M; Henter J-I; Valentin H; Delprat C
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2021;192(1):200-211
Severe congenital neutropenia-associated JAGN1 mutations unleash a calpain-dependent cell death programme in myeloid cells
Khandagale A; Holmlund T; Entesarian M; Nilsson D; Kalwak K; Klaudel-Dreszler M; Carlsson G; Henter J-I; Nordenskjold M; Fadeel B
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: BLOOD ADVANCES. 2020;4(15):3754-3766
Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study
Bergsten E; Horne A; Myrberg IH; Arico M; Astigarraga I; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Nanduri V; Rosso DA; Sieni E; Winiarski J; Henter J-I
Article: CLINICAL IMMUNOLOGY. 2020;215:108418
Foxp3⁺ Tregs from Langerhans cell histiocytosis lesions co-express CD56 and have a definitively regulatory capacity
Mitchell J; Kelly J; Kvedaraite E; Greenwood TVB; Henter J-I; Pellicci DG; Berzins SP; Kannourakis G
Article: CLINICAL INFECTIOUS DISEASES. 2020;70(11):2247-2255
Dengue Infection Complicated by Hemophagocytic Lymphohistiocytosis: Experiences From 180 Patients With Severe Dengue
Kan FK; Tan CC; Greenwood TVB; Khalid KE; Supramaniam P; Myrberg IH; Tan LH; Henter J-I
Article: PEDIATRIC BLOOD & CANCER. 2020;67(4):e28184
Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease
Torralba-Raga L; Tesi B; Chiang SCC; Schlums H; Nordenskjoeld M; Horne A; Henter J-I; Meeths M; Abdelhaleem M; Weitzman S; Bryceson Y
Article: EMBO MOLECULAR MEDICINE. 2020;12(3):e10419
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy
Rudd SG; Tsesmetzis N; Sanjiv K; Paulin CBJ; Sandhow L; Kutzner J; Myrberg IH; Bunten SS; Axelsson H; Zhang SM; Rasti A; Makela P; Coggins SA; Tao S; Suman S; Branca RM; Mermelekas G; Wiita E; Lee S; Walfridsson J; Schinazi RF; Kim B; Lehtio J; Rassidakis GZ; Tamm KP; Warpman-Berglund U; Heyman M; Grander D; Lehmann S; Lundback T; Qian H; Henter J-I; Schaller T; Helleday T; Herold N
Article: CYTOKINE. 2020;126:154877
High levels of plasma interleukin-17A are associated with severe neurological sequelae in Langerhans cell histiocytosis
Ismail MB; Akefeldt SO; Lourda M; Gavhed D; Arico M; Henter J-I; Delprat C; Valentin H
Article: METHODSX. 2020;7:100997
Comparison of three different ELISAs for the detection of recombinant, native and plasma IL-17A
Ismail MB; Akefeldt SO; Lourda M; Gavhed D; Gayet R; Arico M; Henter J-I; Delprat C; Valentin H
Article: MINERVA ANESTESIOLOGICA. 2019;85(12):1289-1298
Elevated ferritin and soluble CD25 in critically ill patients are associated with parameters of (hyper) inflammation and lymphocyte cytotoxicity
von Bahr Greenwood T; Palmkvist-Kaijser K; Chiang SC; Tesi B; Bryceson YT; Hjelmqvist H; Henter J-I
Article: BLOOD. 2019;133(23):2465-2477
Recommendations for the management of hemophagocytic lymphohistiocytosis in adults
La Rosee P; Horne A; Hines M; Greenwood TVB; Machowicz R; Berliner N; Birndt S; Gil-Herrera J; Girschikofsky M; Jordan MB; Kumar A; van Laar JAM; Lachmann G; Nichols KE; Ramanan AV; Wang Y; Wang Z; Janka G; Henter J-I
Article: CANCER. 2019;125(11):1848-1854
Haploinsufficiency of UNC13D increases the risk of lymphoma
Lofstedt A; Ahlm C; Tesi B; Bergdahl IA; Nordenskjold M; Bryceson YT; Henter J-I; Meeths M
Article: SCIENTIFIC REPORTS. 2018;8(1):16506
Altered Populations of Unconventional T Cell Lineages in Patients with Langerhans Cell Histiocytosis
Mitchell J; Kvedaraite E; Greenwood TVB; Henter J-I; Pellicci DG; Berzins SP; Kannourakis G
Article: BLOOD CANCER JOURNAL. 2018;8(11):98
Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens
Rassidakis GZ; Herold N; Myrberg IH; Tsesmetzis N; Rudd SG; Henter J-I; Schaller T; Ng S-B; Chng WJ; Yan B; Ng CH; Ravandi F; Andreeff M; Kantarjian HM; Medeiros LJ; Xagoraris I; Khoury JD
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2018;6(5):1508-1517
Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society
Ehl S; Astigarraga I; Greenwood TVB; Hines M; Horne A; Ishii E; Janka G; Jordan MB; La Rosee P; Lehmberg K; Machowicz R; Nichols KE; Sieni E; Wang Z; Henter J-I
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2018;142(1):317-321.e8
A RAB27A 5′ untranslated region structural variant associated with late-onset hemophagocytic lympho-histiocytosis and normal pigmentation
Tesi B; Rascon J; Chiang SCC; Burnyte B; Lofstedt A; Fasth A; Heizmann M; Juozapaite S; Kiudeliene R; Kvedaraite E; Miseviciene V; Muleviciene A; Mueller M-L; Nordenskjold M; Matuzeviciene R; Samaitiene R; Speckmann C; Stankeviciene S; Zekas V; Voss M; Ehl S; Vaiciene-Magistris N; Henter J-I; Meeths M; Bryceson YT
Article: BLOOD. 2017;130(25):2728-2738
Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study
Bergsten E; Horne A; Arico M; Astigarraga I; Egeler RM; Filipovich AH; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Montgomery S; Nanduri V; Rosso D; Henter J-I
Article: EXPERIMENTAL HEMATOLOGY. 2017;52:32-39
With me or against me: Tumor suppressor and drug resistance activities of SAMHD 1
Herold N; Rudd SG; Sanjiv K; Kutzner J; Myrberg IH; Paulin CBJ; Olsen TK; Helleday T; Henter J-I; Schaller T
Article: CELL CYCLE. 2017;16(11):1029-1038
SAMHD1 protects cancer cells from various nucleoside-based antimetabolites
Herold N; Rudd SG; Sanjiv K; Kutzner J; Bladh J; Paulin CBJ; Helleday T; Henter J-I; Schaller T
Article: BLOOD. 2017;129(16):2266-2279
Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms
Tesi B; Davidsson J; Voss M; Rahikkala E; Holmes TD; Chiang SCC; Komulainen-Ebrahim J; Gorcenco S; Nilsson AR; Ripperger T; Kokkonen H; Bryder D; Fioretos T; Henter J-I; Mottonen M; Niinimaki R; Nilsson L; Pronk CJ; Puschmann A; Qian H; Uusimaa J; Moilanen J; Tedgard U; Cammenga J; Bryceson YT
Article: NATURE MEDICINE. 2017;23(2):256-263
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Herold N; Rudd SG; Ljungblad L; Sanjiv K; Myrberg IH; Paulin CBJ; Heshmati Y; Hagenkort A; Kutzner J; Paget BDG; Calderon-Montano JM; Loseva O; Jemth A-S; Bulli L; Axelsson H; Tesi B; Valerie NCK; Hoglund A; Bladh J; Wiita E; Sundin M; Uhlin M; Rassidakis G; Heyman M; Tamm KP; Warpman-Berglund U; Walfridsson J; Lehmann S; Grander D; Lundback T; Kogner P; Henter J-I; Helleday T; Schaller T
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:426
Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak-Higashi Syndrome Patients
Chiang SCC; Wood SM; Tesi B; Akar HH; Al-Herz W; Ammann S; Belen FB; Caliskan U; Kaya Z; Lehmberg K; Patiroglu T; Tokgoz H; Unuvar A; Introne WJ; Henter J-I; Nordenskjold M; Ljunggren H-G; Meeths M; Ehl S; Krzewski K; Bryceson YT
Article: GUT. 2016;65(10):1632-1641
Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD
Kvedaraite E; Lourda M; Idestrom M; Chen P; Olsson-Akefeldt S; Forkel M; Gavhed D; Lindforss U; Mjosberg J; Henter J-I; Svensson M
Article: ACTA PAEDIATRICA. 2016;105(9):1094-1099
Children with cancer share their views: tell the truth but leave room for hope
Jalmsell L; Lovgren M; Kreicbergs U; Henter J-I; Frost B-M
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2016;36(5):480-489
Successful Hematopoietic Stem Cell Transplantation in a Patient with LPS-Responsive Beige-Like Anchor (LRBA) Gene Mutation
Tesi B; Priftakis P; Lindgren F; Chiang SCC; Kartalis N; Lofstedt A; Lorinc E; Henter J-I; Winiarski J; Bryceson YT; Meeths M
Article: BLOOD. 2016;127(25):3281-3290
The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis
Hartz B; Marsh R; Rao K; Henter J-I; Jordan M; Filipovich L; Bader P; Beier R; Burkhardt B; Meisel R; Schulz A; Winkler B; Albert MH; Greil J; Karasu G; Woessmann W; Corbacioglu S; Gruhn B; Holter W; Kuehl J-S; Lang P; Seidel MG; Veys P; Lofstedt A; Ammann S; Ehl S; Janka G; Mueller I; Lehmberg K
Article: CLINICS. 2016;71(4):205-209
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
Zhang Z; Wang J; Ji B; Greenwood TVB; Zhang Y; Wang Y; Kong D; Li A; Jiang Y; Guo Y; Liu X; Wang Y; Dou A; Li N; Henter J-I; Sun G; Zheng C
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(3):481-489
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative
Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(3):566-576
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative
Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
Article: RMD OPEN. 2016;2(1):e000161
Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic A; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
Article: GENOME MEDICINE. 2015;7:130
Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis
Tesi B; Lagerstedt-Robinson K; Chiang SCC; Ben Bdira E; Abboud M; Belen B; Devecioglu O; Fadoo Z; Yeoh AEJ; Erichsen HC; Mottonen M; Akar HH; Hastbacka J; Kaya Z; Nunes S; Patiroglu T; Sabel M; Saribeyoglu ET; Tvedt TH; Unal E; Unal S; Unuvar A; Meeths M; Henter J-I; Nordenskjold M; Bryceson YT
Article: LANCET HAEMATOLOGY. 2015;2(12):e536-e542
Cancer risk in relatives of patients with a primary disorder of lymphocyte cytotoxicity: a retrospective cohort study
Lofstedt A; Chiang SCC; Oneloev E; Bryceson YT; Meeths M; Henter J-I
Article: PEDIATRIC BLOOD & CANCER. 2015;62(12):2094-2100
Spectrum of Atypical Clinical Presentations in Patients With Biallelic PRF1 Missense Mutations
Tesi B; Chiang SCC; El-Ghoneimy D; Hussein AA; Langenskiold C; Wali R; Fadoo Z; Silva JP; Lecumberri R; Unal S; Nordenskjold M; Bryceson YT; Henter J-I; Meeths M
Article: BLOOD. 2015;126(12):1415-1423
Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 study
Donadieu J; Bernard F; van Noesel M; Barkaoui M; Bardet O; Mura R; Arico M; Piguet C; Gandemer V; Alla CA; Clausen N; Jeziorski E; Lambilliote A; Weitzman S; Henter JI; Van Den Bos C
Article: HAEMATOLOGICA. 2015;100(8):997-1004
Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies
Lehmberg K; Nichols KE; Henter J-I; Girschikofsky M; Greenwood T; Jordan M; Kumar A; Minkov M; La Rosee P; Weitzman S
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2015;169(2):241-248
Lack of bone lesions at diagnosis is associated with inferior outcome in multisystem langerhans cell histiocytosis of childhood
Arico M; Astigarraga I; Braier J; Donadieu J; Gadner H; Glogova E; Grois N; Henter J-I; Janka G; McClain KL; Ladisch S; Poetschger U; Rosso D; Thiem E; Weitzman S; Windebank K; Minkov M
Article: DEATH STUDIES. 2015;39(2):111-117
On the Child's Own Initiative: Parents Communicate with Their Dying Child About Death
Jalmsell L; Kontio T; Stein M; Henter J-I; Kreicbergs U
Article: PEDIATRIC BLOOD & CANCER. 2015;62(2):346-352
Incidence and Clinical Presentation of Primary Hemophagocytic Lymphohistiocytosis in Sweden
Meeths M; Horne A; Sabel M; Bryceson YT; Henter J-I
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2014;49(8):950-957
Pediatric Crohn's disease from onset to adulthood: granulomas are associated with an early need for immunomodulation
Idestrom M; Rubio CA; Onelov E; Henter J-I; Fagerberg UL; Finkel Y
Article: CLINICAL IMMUNOLOGY. 2014;153(1):112-122
Detection of IL-17A-producing peripheral blood monocytes in Langerhans cell histiocytosis patients
Lourda M; Olsson-Akefeldt S; Gavhed D; Bjornfot S; Clausen N; Hjalmars U; Sabel M; Tazi A; Arico M; Delprat C; Henter J-I; Svensson M
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 2014;31(3):285-292
Hemophagocytic Lymphohistiocytosis in Infants: A Single Center Experience from India
Ramzan M; Yadav SP; Kharya G; Chinnabhandar V; Enteserian M; Henter JI; Sachdeva A
Article: ANTI-CANCER DRUGS. 2014;25(3):282-288
Bortezomib and IL-12 produce synergetic anti-multiple myeloma effects with reduced toxicity to natural killer cells
Wang X; Feng X; Wang J; Shao N; Ji C; Ma D; Henter J-I; Fadeel B; Zheng C
Article: FRONTIERS IN IMMUNOLOGY. 2014;4:515
An N-terminal missense mutation in STX11 causative of FHLA abrogates syntaxin-11 binding to Munc18-2
Muller M-L; Chiang SCC; Meeths M; Tesi B; Entesarian M; Nilsson D; Wood SM; Nordenskjold M; Henter J-I; Naqvi A; Bryceson YT
Article: PLOS ONE. 2014;9(10):e109586
Polyclonal T-Cells Express CD1a in Langerhans Cell Histiocytosis (LCH) Lesions
West JA; Olsen SL; Mitchell JM; Priddle RE; Luke JM; Akefeldt SO; Henter J-I; Turville C; Kannourakis G
Article: ACTA PAEDIATRICA. 2013;102(7):744-748
Transition to noncurative end-of-life care in paediatric oncology - a nationwide follow-up in Sweden
Jalmsell L; Forslund M; Hansson MG; Henter J-I; Kreicbergs U; Frost B-M
Article: BLOOD. 2013;121(25):5006-5014
Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis
Gadner H; Minkov M; Grois N; Poetschger U; Thiem E; Arico M; Astigarraga I; Braier J; Donadieu J; Henter J-I; Janka-Schaub G; McClain KL; Weitzman S; Windebank K; Ladisch S
Article: HAEMATOLOGICA. 2013;98(5):760-764
Development of classical Hodgkin's lymphoma in an adult with biallelic STXBP2 mutations.
Machaczka M; Klimkowska M; Chiang SCC; Meeths M; Müller M-L; Gustafsson B; Henter J-I; Bryceson YT
Article: BLOOD. 2013;121(8):1345-1356
Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production
Chiang SCC; Theorell J; Entesarian M; Meeths M; Mastafa M; Al-Herz W; Frisk P; Gilmour KC; Ifversen M; Langenskiold C; Machaczka M; Naqvi A; Payne J; Perez-Martinez A; Sabel M; Unal E; Unal S; Winiarski J; Nordenskjold M; Ljunggren H-G; Henter J-I; Bryceson YT
Article: PLOS ONE. 2013;8(2):e56865
Chemoresistance of Human Monocyte-Derived Dendritic Cells Is Regulated by IL-17A
Akefeldt SO; Maisse C; Belot A; Mazzorana M; Salvatore G; Bissay N; Jurdic P; Arico M; Rabourdin-Combe C; Henter J-I; Delprat C
Article: ACTA PAEDIATRICA. 2013;102(1):78-82
Ovarian failure in HAX1-deficient patients: is there a gender-specific difference in pubertal development in severe congenital neutropenia or Kostmann disease?
Carlsson G; Kristrom B; Nordenskjold M; Henter J-I; Fadeel B
Article: STEM CELLS AND DEVELOPMENT. 2012;21(17):3147-3151
Treatment of Familial Hemophagocytic Lymphohistiocytosis with Third-Party Mesenchymal Stromal Cells
Mougiakakos D; Machaczka M; Jitschin R; Klimkowska M; Entesarian M; Bryceson YT; Henter J-I; Sander B; Le Blanc K
Article: ACTA PAEDIATRICA. 2012;101(11):1151-1155
Langerhans cell histiocytosis in children born 1982-2005 after in vitro fertilization
Akefeldt SO; Finnstrom O; Gavhed D; Henter J-I
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2012;158(3):363-369
Incidence of severe congenital neutropenia in Sweden and risk of evolution to myelodysplastic syndrome/leukaemia
Carlsson G; Fasth A; Berglof E; Lagerstedt-Robinson K; Nordenskjold M; Palmblad J; Henter J-I; Fadeel B
Article: ACTA PAEDIATRICA. 2012;101(8):805-807
The need for worldwide policy and action plans for rare diseases
Forman J; Taruscio D; Llera VA; Barrera LA; Cote TR; Edfjaell C; Gavhed D; Haffner ME; Nishimura Y; Posada M; Tambuyzer E; Groft SC; Henter J-I
Article: ACTA PAEDIATRICA. 2012;101(7):761-766
Duration and morbidity of chronic immune thrombocytopenic purpura in children: five-year follow-up of a Nordic cohort
Rosthoj S; Rajantie J; Treutiger I; Zeller B; Tedgard U; Henter J-I
Article: MICROBIOLOGY AND IMMUNOLOGY. 2012;56(6):378-384
Killer cell immunoglobulin-like receptor gene polymorphisms predispose susceptibility to Epstein-Barr virus associated hemophagocytic lymphohistiocytosis in Chinese children
Qiang Q; Xie Z; Liu C; Huang Z; Xu J; Ai J; Zheng C; Henter J-I; Shen K
Article: BLOOD. 2012;119(12):2754-2763
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Bryceson YT; Pende D; Maul-Pavicic A; Gilmour KC; Ufheil H; Vraetz T; Chiang SC; Marcenaro S; Meazza R; Bondzio I; Walshe D; Janka G; Lehmberg K; Beutel K; zur Stadt U; Binder N; Arico M; Moretta L; Henter J-I; Ehl S
Article: ACTA PAEDIATRICA. 2012;101(3):313-318
Risk factors for early death in children with haemophagocytic lymphohistiocytosis
Trottestam H; Berglof E; Horne A; Onelov E; Beutel K; Lehmberg K; Sieni E; Silfverberg T; Arico M; Janka G; Henter J-I
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(1):129-141
Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules
Dabrazhynetskaya A; Ma J; Guerreiro-Cacais AO; Arany Z; Rudd E; Henter J-I; Karre K; Levitskaya J; Levitsky V
Article: BLOOD. 2011;118(22):5783-5793
Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D
Meeths M; Chiang SCC; Wood SM; Entesarian M; Schlums H; Bang B; Nordenskjold E; Bjorklund C; Jakovljevic G; Jazbec J; Hasle H; Holmqvist B-M; Rajic L; Pfeifer S; Rosthoj S; Sabel M; Salmi TT; Stokland T; Winiarski J; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I; Bryceson YT
Article: BLOOD. 2011;118(17):4577-4584
Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol
Trottestam H; Horne A; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
Article: BONE MARROW TRANSPLANTATION. 2011;46(8):1063-1070
Hematopoietic stem cell transplantation in children with cancer and the risk of long-term psychological morbidity in the bereaved parents
Jalmsell L; Onelov E; Steineck G; Henter J-I; Kreicbergs U
Article: JOURNAL OF MEDICAL GENETICS. 2011;48(5):343-352
Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3
Sieni E; Cetica V; Santoro A; Beutel K; Mastrodicasa E; Meeths M; Ciambotti B; Brugnolo F; zur Stadt U; Pende D; Moretta L; Griffiths GM; Henter J-I; Janka G; Arico M
Article: PEDIATRIC BLOOD & CANCER. 2011;56(3):444-451
Hematopoietic Stem Cell Transplantation in Severe Congenital Neutropenia
Carlsson G; Winiarski J; Ljungman P; Ringden O; Mattsson J; Nordenskjold M; Touw I; Henter J-I; Palmblad J; Fadeel B; Hagglund H
Article: PEDIATRIC BLOOD & CANCER. 2011;56(2):250-257
Incidence and Pattern of Radiological Central Nervous System Langerhans Cell Histiocytosis in Children: A Population Based Study
Laurencikas E; Gavhed D; Stalemark H; van't Hooft I; Prayer D; Grois N; Henter J-I
Article: BLOOD. 2010;116(15):2635-2643
Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2
Meeths M; Entesarian M; Al-Herz W; Chiang SCC; Wood SM; Al-Ateeqi W; Almazan F; Boelens JJ; Hasle H; Ifversen M; Lund B; van den Berg JM; Gustafsson B; Hjelmqvist H; Nordenskjold M; Bryceson YT; Henter J-I
Article: MOLECULAR IMMUNOLOGY. 2010;47(14):2388-2396
The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells
Feng X; Yan J; Wang Y; Zierath JR; Nordenskjold M; Henter J-I; Fadeel B; Zheng C
Article: JOURNAL OF PEDIATRICS. 2010;156(6):873-881.e1
Central Nervous System Disease in Langerhans Cell Histiocytosis
Grois N; Fahrner B; Arceci RJ; Henter J-I; McClain K; Lassmann H; Nanduri V; Prosch H; Prayer D
Article: PEDIATRIC BLOOD & CANCER. 2010;54(5):751-757
Anxiety is Contagious-Symptoms of Anxiety in the Terminally Ill Child Affect Long-Term Psychological Well-Being in Bereaved Parents
Jalmsell L; Kreicbergs U; Onelov E; Steineck G; Henter J-I
Article: PEDIATRIC BLOOD & CANCER. 2010;54(4):563-572
Clinical Presentation of Griscelli Syndrome Type 2 and Spectrum of RAB27A Mutations
Meeths M; Bryceson YT; Rudd E; Zheng C; Wood SM; Ramme K; Beutel K; Hasle H; Heilmann C; Hultenby K; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: PEDIATRIC BLOOD & CANCER. 2010;54(3):408-415
Frequency and Development of CNS Involvement in Chinese Children With Hemophagocytic Lymphohistiocytosis
Yang S; Zhang L; Jia C; Ma H; Henter J-I; Shen K
Article: PEDIATRIC BLOOD & CANCER. 2009;53(7):1264-1270
Biomarkers in the Cerebrospinal Fluid and Neurodegeneration in Langerhans Cell Histiocytosis
Gavhed D; Akefeldt SO; Osterlundh G; Laurencikas E; Hjorth L; Blennow K; Rosengren L; Henter J-I
Article: BLOOD. 2009;114(19):4117-4127
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
Wood SM; Meeths M; Chiang SCC; Bechensteen AG; Boelens JJ; Heilmann C; Horiuchi H; Rosthoj S; Rutynowska O; Winiarski J; Stow JL; Nordenskjold M; Henter J-I; Ljunggren H-G; Bryceson YT
Article: HAEMATOLOGICA. 2009;94(4):470-478
Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxicity
Wang X; Ottosson A; Ji C; Feng X; Nordenskjoeld M; Henter J-I; Fadeel B; Zheng C
Article: PEDIATRIC BLOOD & CANCER. 2009;52(4):527-529
Fatal Hemophagocytic Lymphohistiocytosis in X-Linked Chronic Granulomatous Disease Associated With a Perforin Gene Variant
van Montfrans JA; Rudd E; van de Corput L; Henter J-I; Nikkels P; Wulffraat N; Boelens JJ
Article: PEDIATRIC BLOOD & CANCER. 2009;52(2):268-272
Treatment of the X-Linked Lymphoproliferative, Griscelli and Chediak-Higashi Syndromes by HLH Directed Therapy
Trottestam H; Beutel K; Meeths M; Carlsen N; Heilmann C; Pasic S; Webb D; Hasle H; Henter J-I
Article: LAKARTIDNINGEN. 2008;105(51-52):3737-3742
[Langerhans cell histiocytosis: new light over pathogenesis. 75 years since Sture Siwe's classic work on "systemic reticuloendotheliosis"].
Fadeel B; Olsson S; Jakobson A; Hjorth L; Osterlundh G; Henter J-I
Article: JOURNAL OF PEDIATRICS. 2008;153(5):700-705.e2
Reactivations in Multisystem Langerhans Cell Histiocytosis: Data of the International LCH Registry
Minkov M; Steiner M; Poetschger U; Arico M; Braier J; Donadieu J; Grois N; Henter J-I; Janka G; McClain K; Weitzman S; Windebank K; Ladisch S; Gadner H
Article: PEDIATRIC BLOOD & CANCER. 2008;51(5):669-674
Neuropsychological sequelae in patients with neurodegenerative Langerhans cell histiocytosis
van't Hooft I; Gavhed D; Laurencilkas E; Henter J-I
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;143(1):75-83
Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis
Horne A; Ramme KG; Rudd E; Zheng C; Wali Y; al-Lamki Z; Guergey A; Yalman N; Nordenskjold M; Henter J-I
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(4):388-400
Central nervous system involvement in severe congenital neutropenia:: neurological and neuropsychological abnormalities associated with specific HAX1 mutations
Carlsson G; van't Hooft I; Melin M; Entesarian M; Laurencikas E; Nennesmo I; Trebinska A; Grzybowska E; Palmblad J; Dahl N; Nordenskjold M; Fadeel B; Henter J-I
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;142(3):469-479
Syntaxin-11 is expressed in primary human monocytes/macrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG-opsonized target cells
Zhang S; Ma D; Wang X; Celkan T; Nordenskjoeld M; Henter J-I; Fadeel B; Zheng C
Article: PEDIATRIC BLOOD & CANCER. 2008;51(1):76-81
Incidence of Langerhans cell histiocytosis in children:: A population-based study
Stalemark H; Laurencikas E; Karis J; Gavhed D; Fadeel B; Henter J-I
Article: LANCET. 2008;371(9629):2039-2041
Why rare diseases are an important medical and social issue
Schieppati A; Henter J-I; Daina E; Aperia A
Article: PEDIATRIC BLOOD & CANCER. 2008;50(5):1067-1069
Sequence analysis of the SRGN, AP3B1, ARF6, and SH2D1A genes in familial hemophagocytic lymphohistiocytosis
Ma D; Rudd E; Edner J; Gavhed S; Ramme KG; Fadeel B; Nordenskjoeld M; Henter J-I; Zheng C
Article: BLOOD. 2008;111(5):2556-2562
Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification
Gadner H; Grois N; Poetschger U; Minkov M; Arico M; Braier J; Broadbent V; Donadieu J; Henter J-I; McCarter R; Ladisch S
Article: JOURNAL OF MEDICAL GENETICS. 2008;45(3):134-141
Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis
Rudd E; Bryceson YT; Zheng C; Edner J; Wood SM; Ramme K; Gavhed S; Gurgey A; Hellebostad M; Bechensteen AG; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: CLINICAL INFECTIOUS DISEASES. 2008;46(4):528-536
Parvovirus B19 infection in children with acute lymphoblastic leukemia is associated with cytopenia resulting in prolonged interruptions of chemotherapy
Lindblom A; Heyman M; Gustafsson I; Norbeck O; Kaldensjo T; Vernby A; Henter J-I; Tolfvenstam T; Broliden K
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(3):327-335
Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis
Horne A; Trottestam H; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
Article: JOURNAL OF MEDICAL GENETICS. 2008;45(1):15-21
Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis due to perforin mutations
Trizzino A; Stadt UZ; Ueda I; Risma K; Janka G; Ishii E; Beutel K; Sumegi J; Cannella S; Pende D; Mian A; Henter J-I; Griffiths G; Santoro A; Filipovich A; Arico M
Article: NATURE MEDICINE. 2008;14(1):81-87
Langerhans cell histiocytosis reveals a new IL-17A dependent pathway of dendritic cell fusion
Coury F; Annels N; Rivollier A; Olsson S; Santoro A; Speziani C; Azocar O; Flacher M; Djebali S; Tebib J; Brytting M; Egeler RM; Rabourdin-Combe C; Henter J-I; Arico M; Delprat C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;363(4):989-993
VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice
Zheng C; Skold MK; Li J; Nennesmo I; Fadeel B; Henter J-I
Article: ACTA PAEDIATRICA. 2007;96(11):1703-1706
Severe bacteria-associated hemophagocytic lymphohistiocytosis in an extremely premature infant
Edner J; Rudd E; Zheng C; Dahlander A; Eksborg S; Schneider EM; Edner A; Henter J-I
Article: BLOOD. 2007;110(6):1906-1915
Defective cytotoxic lymphocyte degranulation in syntaxin-11-deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
Bryceson YT; Rudd E; Zheng C; Edner J; Ma D; Wood SM; Bechensteen AG; Boelens JJ; Celkan T; Farah RA; Hultenby K; Winiarski J; Roche PA; Nordenskjold M; Henter J-I; Long EO; Ljunggren H-G
Article: PEDIATRIC BLOOD & CANCER. 2007;49(3):323-328
Brief reports - Pulmonary function testing and pulmonary Langerhans cell histiocytosis
Bernstrand C; Cederlund K; Henter J-I
Article: ARCHIVES OF DISEASE IN CHILDHOOD. 2007;92(8):704-707
Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity?
Treutiger I; Rajantie J; Zeller B; Henter J-I; Elinder G; Rosthoj S
Article: LANCET ONCOLOGY. 2007;8(8):706-714
Parents' intellectual and emotional awareness of their child's impending death to cancer:: a population-based long-term follow-up study
Vaidimarsdottir U; Kreicbergs U; Hauksdottir A; Hunt H; Oneloev E; Henter J-L; Steineck G
Article: BLOOD. 2007;109(12):5157-5159
Fatal agranulocytosis after deferiprone therapy in a child with Diamond-Blackfan anemia
Henter J-I; Karlen J
Article: EUROPEAN JOURNAL OF PEDIATRICS. 2007;166(6):589-593
Simultaneous manifestation of fulminant infectious mononucleosis with haemophagocytic syndrome and B-cell lymphoma in X-linked lymphoproliferative disease
Huegle B; Astigarraga I; Henter J-I; Porwit-MacDonald A; Meindl A; Schuster V
Article: TRANSFUSION. 2007;47(5):911-917
Fetal hemolytic anemia and intrauterine death caused by anti-M immunization
Wikman A; Edner A; Gryfelt G; Jonsson B; Henter J-I
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;137(2):166-169
Low plasma levels of the protein pro-LL-37 as an early indication of severe disease in patients with chronic neutropenia
Karlsson J; Carlsson G; Ramme KG; Hagglund H; Nordenskjold M; Henter J-I; Palmblad J; Putsep K; Andersson M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;353(3):571-575
Assignment of the gene locus for severe congenital neutropenia to chromosome 1q22 in the original Kostmann family from Northern Sweden
Melin M; Entesarian M; Carlsson G; Garwicz D; Klein C; Fadeel B; Nordenskjold M; Palmblad J; Henter JI; Dahl N
Article: NATURE GENETICS. 2007;39(1):86-92
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
Klein C; Grudzien M; Appaswamy G; Germeshausen M; Sandrock I; Schaffer AA; Rathinam C; Boztug K; Schwinzer B; Rezaei N; Bohn G; Melin M; Carlsson G; Fadeel B; Dahl N; Palmblad J; Henter J-I; Zeidler C; Grimbacher B; Welte K
Article: LAKARTIDNINGEN. 2006;103(50-52):4022-4027
[Kostmann's syndrome largely elucidated--by Swedish research. 50 years since Rolf Kostmann's pioneering work on severe congenital neutropenia].
Carlsson G; Garwicz D; Nordenskjöld M; Fadeel B; Palmblad J; Henter J-I
Article: LAKARTIDNINGEN. 2006;103(15-16):1180-1181
[Can cytostatics be effective in severe avian influenza? The disease picture has similarities with hemophagocytic lymphohistiocytosis].
Henter J-I
Article: PEDIATRICS. 2006;117(4):1314-1320
Symptoms affecting children with malignancies during the last month of life:: A nationwide follow-up
Jalmsell L; Kreicbergs U; Onelöv E; Steineck G; Henter JI
Article: JOURNAL OF PERIODONTOLOGY. 2006;77(4):744-751
Periodontal disease in patients from the original Kostmann family with severe congenital neutropenia
Carlsson G; Wahlin Y-B; Johansson A; Olsson A; Eriksson T; Claesson R; Hanstrom L; Henter J-I
Article: JOURNAL OF MEDICAL GENETICS. 2006;43(4):e14
Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis:: association with disease-free remissions and haematopoietic malignancies -: art. no. e14
Rudd E; Ericson KG; Zheng C; Uysal Z; Özkan A; Gürgey A; Fadeel B; Nordenskjöld M; Henter JI
Article: LANCET. 2006;367(9513):870-873
Cytotoxic therapy for severe avian influenza A (H5N1) infection
Henter JI; Chow CB; Leung CW; Lau YL
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2006;28(3):605-617
Combined spectral karyotyping, comparative genomic hybridization, and in vitro apoptyping of a panel of Burkitt's lymphoma-derived B cell lines reveals an unexpected complexity of chromosomal aberrations and a recurrence of specific abnormalities in chemoresistant cell lines
Karpova MB; Schoumans J; Blennow E; Ernberg I; Henter JI; Smirnov AF; Nordenskjöld M; Fadeel B
Article: PEDIATRIC RESEARCH. 2006;59(2):281-286
Elevated serum levels of the decoy receptor osteoprotegerin in children with langerhans cell histiocytosis
Rosso DA; Karis J; Braier JL; Henter JI; Fadeel B
Article: PEDIATRIC BLOOD & CANCER. 2006;46(2):228-233
Risk factors for diabetes insipidus in langerhans cell histiocytosis
Grois N; Pötschger U; Prosch H; Minkov M; Arico M; Braier J; Henter JI; Janka-Schaub G; Ladisch S; Ritter J; Steiner M; Unger E; Gadner H
Article: INTERNATIONAL JOURNAL OF CANCER. 2006;118(1):246-252
Betulinic acid, a natural cytotoxic agent, fails to trigger apoptosis in human Burkitt's lymphoma-derived B-cell lines
Karpova MB; Sanmun D; Henter JI; Smirnov AF; Fadeel B
Article: ACTA PAEDIATRICA. 2005;94(8):1073-1084
Long-term follow-up of Langerhans cell histiocytosis:: 39 years' experience at a single centre
Bernstrand C; Sandstedt B; Åhström L; Henter JI
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):658-666
Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance
Horne A; Zheng CY; Lorenz I; Löfstedt M; Montgomery SM; Janka G; Henter JI; Schneider EM
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):622-630
Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis
Horne A; Janka G; Egeler RM; Gadner H; Imashuku S; Ladisch S; Locatelli F; Montgomery SM; Webb D; Winiarski J; Filipovich AH; Henter JI
Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2005;27(6):301-306
Immunohistochemical detection of the apoptosis-related proteins FADD, FLICE, and FLIP in langerhans cell histiocytosis
Bank MI; Gudbrand C; Rengtved P; Carstensen H; Fadeel B; Henter JI; Petersen BL
Article: LAKARTIDNINGEN. 2005;102(18-19):1444-1446
[Enigmatic diseases in children. Still a lot of questions left in spite of great research progress on LCH and HLH].
Fadeel B; Trottestam H; Löfstedt M; Gavhed D; Henter J-I
Article: HUMAN MOLECULAR GENETICS. 2005;14(6):827-834
Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
zur Stadt U; Schmidt S; Diler AS; Henter JI; Kabisch H; Schneppenheim R; Nürnberg P; Janka G; Hennies HC
Article: ACTA PAEDIATRICA. 2005;94(2):178-184
Childhood idiopathic thrombocytopenic purpura in the Nordic countries:: Epidemiology and predictors of chronic disease
Zeller B; Rajantie J; Hedlund-Treutiger I; Tedgård U; Wesenberg F; Jonsson AG; Henter JI; Rosthoj S
Article: PSYCHOLOGICAL MEDICINE. 2004;34(8):1431-1441
Anxiety and depression in parents 4-9 years after the loss of a child owing to a malignancy:: a population-based follow-up
Kreicbergs U; Valdimarsdóttir U; Onelöv E; Henter JI; Steineck G
Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2004;26(11):706-711
Tumor necrosis factor, interleukin 11, and leukemia inhibitory factor produced by Langerhans cells in Langerhans cell histiocytosis
By UA; Tani E; Andersson U; Henter JI
Article: ANNALS OF NEUROLOGY. 2004;56(4):564-567
Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS
Zheng CY; Nennesmo I; Fadeel B; Henter JI
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2004;351(12):1175-1186
Talking about death with children who have severe malignant disease
Kreicbergs U; Valdimarsdóttir U; Onelöv E; Henter JI; Steineck G
Article: LANCET. 2004;364(9436):787-789
A population-based nationwide study of parents' perceptions of a questionnaire on their child's death due to cancer
Kreicbergs U; Valdimarsdóttir U; Steineck G; Henter JI
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2004;126(1):127-132
Efficacy and safety of two different rG-CSF preparations in the treatment of patients with severe congenital neutropenia
Carlsson G; Åhlin A; Dahllöf G; Elinder G; Henter JI; Palmblad J
Article: BLOOD. 2004;103(9):3355-3361
Kostmann syndrome:: severe congenital neutropenia associated with defective expression of Bcl-2, constitutive mitochondrial release of cytochrome c, and excessive apoptosis of myeloid progenitor cells
Carlsson G; Aprikyan AAG; Tehranchi R; Dale DC; Porwit A; Hellström-Lindberg E; Palmblad J; Henter JI; Fadeel B
Article: HAEMATOLOGICA. 2004;89(2):183-188
Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
Imashuku S; Teramura T; Tauchi H; Ishida Y; Otoh Y; Sawada M; Tanaka H; Watanabe A; Tabata Y; Morimoto A; Hibi S; Henter JI
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 2003;20(8):603-609
Clinical and genetic studies of familial hemophagocytic lymphohistiocytosis in Oman: Need for early treatment
Al-Lamki Z; Wali YA; Pathare A; Ericson KG; Henter JI
Article: JOURNAL OF PEDIATRICS. 2003;143(3):302-307
Duration and morbidity of newly diagnosed idiopathic thrombocytopenic purpura in children: A prospective Nordic study of an unselected cohort
Rosthoj S; Hedlund-Treutiger R; Rajantie J; Zeller B; Jonsson OG; Elinder G; Wesenberg F; Henter JI
Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2003;25(2):139-144
Randomized study of IVIg and high-dose dexamethasone therapy for children with chronic idiopathic thrombocytopenic purpura
Hedlund-Treutiger I; Henter JI; Elinder G
Article: HUMAN GENETICS. 2003;112(1):98-99
Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis
Ericson KG; Fadeel B; Andersson M; Gudmundsson GH; Gürgey A; Yalman N; Janka G; Nordenskjöld M; Henter JI
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2002;119(1):261-264
Familial transient erythroblastopenia of childhood is associated with the chromosome 19q13.2 region but not caused by mutations in coding sequences of the ribosomal protein S19 (RPS19) gene
Gustavsson P; Klar J; Matsson H; Forestier E; Henter JI; Rao S; Seip M; Skeppner G; Dahl N
Article: BLOOD. 2002;100(7):2367-2373
Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
Henter JI; Samuelsson-Horne A; Aricò M; Egeler RM; Elinder G; Filipovich AH; Gadner H; Imashuku S; Komp D; Ladisch S; Webb D; Janka G
Article: JOURNAL OF PEDIATRICS. 2002;141(3):435-440
Brain 18-FDG PET scan in central nervous system Langerhans cell histiocytosis
Calming U; Bemstrand C; Mosskin M; Elander SS; Ingvar M; Henter JI
Article: PEDIATRIC BLOOD & CANCER. 2002;38(5):305-309
Biology and treatment of familial hemophagocytic lymphohistiocytosis: Importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis
Henter JI
Article: ACTA PAEDIATRICA. 2002;91(8):974-977
Findings in familial haemophagocytic lymphohistiocytosis prior to symptomatic presentation
Hafsteinsdóttir S; Jónmundsson GK; Kristinsson JR; Winiarski J; Henter JI; Haraldsson A
Article: PEDIATRIC BLOOD & CANCER. 2001;36(4):459-468
Pulmonary abnormalities at long-term follow-up of patients with Langerhans cell histiocytosis
Bernstrand C; Cederlund K; Sandstedt B; Åhström L; Lundell M; Dahlquist G; Henter JI
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597
Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis
Ericson KG; Fadeel B; Nilsson-Ardnor S; Söderhäll C; Samuelsson A; Janka G; Schneider M; Gürgey A; Yalman N; Révész T; Egeler RM; Jahnukainen K; Storm-Mathiesen I; Haraldsson A; Poole J; de Saint Basile G; Nordenskjöld M; Henter JI
Article: ACTA PAEDIATRICA. 2000;89(11):1389-1392
Smoking preceded pulmonary involvement in adults with Langerhans cell histiocytosis diagnosed in childhood
Bernstrand C; Cederlund K; Åhstrom L; Henter JI
Article: TIDSSKRIFT FOR DEN NORSKE LAEGEFORENING. 2000;120(4):455-458
[Parvovirus B19 infection--an incidious chameleon].
Broliden K; Tolfvenstam T; Papadogiannakis N; Westgren M; Matt P; Lundqvist A; Skjöldebrand-Sparre L; Nyman M; Henter JI
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;266(2):504-511
Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
Fadeel B; Gleiss B; Högstrand K; Chandra J; Wiedmer T; Sims PJ; Henter JI; Orrenius S; Samali A
Article: SCIENCE. 1999;286(5446):1957-1959
Perforin gene defects in familiar hemophagocytic lymphohistiocytosis
Stepp SE; Dufourcq-Lagelouse R; Le Deist F; Bhawan S; Certain S; Mathew PA; Henter JI; Bennett M; Fischer A; Saint Basile GD; Kumar V
Article: LAKARTIDNINGEN. 1999;96(46):5066-5069
[Parvovirus B19 infection--an insidious chameleon].
Broliden K; Tolfvenstam T; Papadogiannakis N; Westgren M; Matt P; Lundqvist A; Skjöldebrand-Sparre L; Nyman M; Henter JI
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1999;106(2):406-415
Induction of apoptosis and caspase activation in cells obtained from familial haemophagocytic lymphohistiocytosis patients
Fadeel B; Orrenius S; Henter JI
Article: LEUKEMIA. 1999;13(5):719-728
Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells
Fadeel B; Hassan Z; Hellström-Lindberg E; Henter JI; Orrenius S; Zhivotovsky B
Article: BLOOD. 1999;93(6):1869-1874
Effective control of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis with immunochemotherapy
Imashuku S; Hibi S; Ohara T; Iwai A; Sako M; Kato M; Arakawa H; Sotomatsu M; Kataoka S; Asami K; Hasegawa D; Kosaka Y; Sano K; Igarashi N; Maruhashi K; Ichimi R; Kawasaki H; Maeda N; Tanizawa A; Arai K; Abe T; Hisakawa H; Miyashita H; Henter JI
Article: PEDIATRIC BLOOD & CANCER. 1999;32(1):25-31
Successful extracorporeal membrane oxygenation in four children with malignant disease and severe Pneumocystis carinii pneumonia
Lindén V; Karlén J; Olsson M; Palmér K; Ehrén H; Henter JI; Kalin M
Article: BLOOD. 1998;92(12):4808-4818
Involvement of caspases in neutrophil apoptosis:: Regulation by reactive oxygen species
Fadeel B; Åhlin A; Henter JI; Orrenius S; Hampton MB
Article: ACTA PAEDIATRICA. 1998;87(10):1085-1087
Elevated erythrocyte sedimentation rate and thrombocytosis as possible indicators of active disease in Langerhans' cell histiocytosis
Calming U; Henter JI
Article: PEDIATRIC BLOOD & CANCER. 1998;31(2):66-72
Persistent B19 parvovirus infection in pediatric malignancies
Broliden K; Tolfvenstam T; Ohlsson S; Henter JI
Article: HISTOPATHOLOGY. 1998;32(4):310-316
Autopsy findings in 27 children with haemophagocytic lymphohistiocytosis
Öst A; Nilsson-Ardnor S; Henter JI
Article: HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA. 1998;12(2):435-444
Infection- and malignancy-associated hemophagocytic syndromes - Secondary hemophagocytic lymphohistiocytosis
Janka G; Imashuku S; Elinder G; Schneider M; Henter JI
Article: HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA. 1998;12(2):417-433
Familial hemophagocytic lymphohistiocytosis -: Primary hemophagocytic lymphohistiocytosis
Henter JI; Aricò M; Elinder G; Imashuku S; Janka G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1998;47(3):229-235
Down-regulation of lymphokine synthesis by intravenous gammaglobulin is dependent upon accessory cells
Skansén-Saphir U; Andersson J; Björk L; Ekberg C; Fehniger TE; Henter JI; Andersson U
Article: ACTA PAEDIATRICA. 1998;87(1):43-47
Transient red cell aplasia in siblings: a common environmental or a common hereditary factor?
Skeppner G; Forestier E; Henter JI; Wranne L
Article: PEDIATRIC BLOOD & CANCER. 1997;29(3):157-166
Contemporary classification of histiocytic disorders
Favara BE; Feller AC; Pauli M; Jaffe ES; Weiss LM; Arico M; Bucsky P; Egeler RM; Elinder G; Gadner H; Gresik M; Henter JI; Imashuku S; JankaSchaub G; Jaffe R; Ladisch S; Nezelof C; Pritchard J
Article: NATURE GENETICS. 1997;16(4):368-371
Diamond-Blackfan anaemia: Genetic homogeneity for a gene on chromosome 19q13 restricted to 1.8 Mb
Gustavsson P; Willig TN; vanHaeringen A; Tchernia G; Dianzani I; Donner M; Elinder G; Henter JI; Nilsson PG; Gordon L; Skeppner G; vantVeerKorthof L; Kreuger A; Dahl N
Article: PEDIATRIC BLOOD & CANCER. 1997;28(5):342-347
HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis
Henter JI; Arico M; Egeler RM; Elinder G; Favara BE; Filipovich AH; Gadner H; Imashuku S; JankaSchaub G; Komp D; Ladisch S; Webb D
Article: JOURNAL OF PEDIATRICS. 1997;130(3):358-365
Neuropathologic findings and neurologic symptoms in twenty-three children with hemophagocytic lymphohistiocytosis
Henter JI; Nennesmo I
Article: ACTA PAEDIATRICA. 1997;86(2):226-227
Prevalence and treatment of chronic idiopathic thrombocytopenic purpura of childhood in Sweden
Hedman A; Henter JI; Hedlund I; Elinder G
Article: ACTA PAEDIATRICA. 1996;85(12):1508-1510
Transient hypertriglyceridemia of infancy
Nilsson A; Ortqvist E; Lagercrantz H; NilssonEhle P; Henter JI
Article: PEDIATRIC BLOOD & CANCER. 1996;27(1):21-25
Elevated circulating levels of interleukin-1 receptor antagonist but not IL-1 agonists in hemophagocytic lymphohistiocytosis
Henter JI; Andersson B; Elinder G; Jakobson A; Lubeck PO; Soder O
Article: ACTA PAEDIATRICA. 1996;85(4):502-504
Intralesional steroids in Langerhans cell histiocytosis of bone
Bernstrand C; Bjork O; Ahstrom L; Henter JI
Article: LAKARTIDNINGEN. 1996;93(1-2):26-30
[Thalassemia, heading for Sweden. A new patient group at Swedish pediatric clinics].
Sandström L; Ljung R; Henter JI; Elinder G
Article: BONE MARROW TRANSPLANTATION. 1995;15(3):331-335
ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN SWEDEN
BOLME P; HENTER JI; WINIARSKI J; ELINDER G; LJUNGMAN P; LONNERHOLM G; RINGDEN O
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Letter: PEDIATRIC BLOOD & CANCER. 2024;71(3):e30850
The ECHO recommendations for dealing with vinblastine shortage affecting standard treatment of systemic Langerhans cell histiocytosis
Papadakis V; Astigarraga I; van den Bos C; Donadieu J; Henter J-I; Jacobs S; Lehrnbecher T; Munthe-Kaas MC; Naeije L; Nanduri V; Nguyen T; Nysom K; Pears J; Raciborska A; Sieni E; Svojgr K; Tzotzola V; Minkov M
Letter: PEDIATRIC RESEARCH. 2022;92(4):912-914
Seasonality of birth month in patients diagnosed with Langerhans cell histiocytosis (LCH)
Close IR; Lee N; Henter J-I
Review: CRITICAL CARE MEDICINE. 2022;50(5):860-872
Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults
Hines MR; Greenwood TVB; Beutel G; Beutel K; Hays JA; Horne A; Janka G; Jordan MB; van Laar JAM; Lachmann G; Lehmberg K; Machowicz R; Miettunen P; La Rosee P; Shakoory B; Zinter MS; Henter J-I
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2022;196(1):248-254
Response to mitogen-activated protein kinase inhibition of neurodegeneration in Langerhans cell histiocytosis monitored by cerebrospinal fluid neurofilament light as a biomarker: a pilot study
Henter J-I; Kvedaraite E; Martin Munoz D; Cheng Munthe-Kaas M; Zeller B; Nystad TA; Bjorklund C; Donner I; Lourda M; Zetterberg H; Blennow K; Herold N; Gavhed D; von Bahr Greenwood T
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2020;191(1):115-119
High prevalence of peripheral lymphopenia in Langerhans cell histiocytosis
Lourda M; Wideskold S; Kvedaraite E; Gavhed D; Akber M; von Bahr Greenwood T; Svensson M; Olsson-Akefeldt S; Henter J-I
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2020;383(6):596-598
Emapalumab in Primary Hemophagocytic Lymphohistiocytosis
Henter J-I; Greenwood TVB; Bergsten E
Other: MOLECULAR MEDICINE. 2020;26(1):17
High systematic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome (Expression of Concern of Vol 20, Pg 538, 2014)
Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Antoine DJ; Andersson U
Review: CURRENT TREATMENT OPTIONS IN NEUROLOGY. 2017;19(1):3
How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?
Horne A; Wickstrom R; Jordan MB; Yeh EA; Naqvi A; Henter J-I; Janka G
Letter: BLOOD. 2016;128(9):1302-1305
Adsorptive depletion of blood monocytes reduces the levels of circulating interleukin-17A in Langerhans cell histiocytosis
Lourda M; Olsson-Akefeldt S; Gavhed D; Nygell UA; Berlin G; Laurencikas E; Greenwood TVB; Svensson M; Henter J-I
Review: BLOOD. 2016;127(22):2672-2681
Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages
Emile J-F; Abla O; Fraitag S; Horne A; Haroche J; Donadieu J; Requena-Caballero L; Jordan MB; Abdel-Wahab O; Allen CE; Charlotte F; Diamond EL; Egeler RM; Fischer A; Gil Herrera J; Henter J-I; Janku F; Merad M; Picarsic J; Rodriguez-Galindo C; Rollins BJ; Tazi A; Vassallo R; Weiss LM
Other: CLINICAL CASE REPORTS. 2016;4(2):165-170
Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok
Fleischmann R; Boehmerle W; von Laffert M; Joehrens K; Mengel A; Hotter B; Lindenberg R; Scheibe F; Koehnlein M; Greenwood TVB; Henter JI; Meisel A
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(6):1638-1641
Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency
Tesi B; Sieni E; Neves C; Romano F; Cetica V; Cordeiro AI; Chiang S; Schlums H; Galli L; Avenali S; Tondo A; Canessa C; Henter J-I; Nordenskjold M; Hsu AP; Holland SM; Neves JE; Azzari C; Bryceson YT
Review: EXPERIMENTAL CELL RESEARCH. 2014;325(1):10-17
Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity
Meeths M; Chiang SCC; Lofstedt A; Muller M-L; Tesi B; Henter J-I; Bryceson YT
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(1):226-228
Combined newborn screening for familial hemophagocytic lymphohistiocytosis and severe T- and B-cell immunodeficiencies
Borte S; Meeths M; Liebscher I; Krist K; Nordenskjold M; Hammarstrom L; von Dobeln U; Henter J-I; Bryceson YT
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2013;162(3):415-418
Novel deep intronic and missense UNC13D mutations in familial haemophagocytic lymphohistiocytosis type 3
Entesarian M; Chiang SCC; Schlums H; Meeths M; Chan M-Y; Mya S-N; Soh S-Y; Nordenskjold M; Henter J-I; Bryceson YT
Review: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2013;2013:701305-11
Targeting BCL2 Family in Human Myeloid Dendritic Cells: A Challenge to Cure Diseases with Chronic Inflammations Associated with Bone Loss
Akefeldt SO; Ismail MB; Valentin H; Arico M; Henter J-I; Delprat C
Editorial comment: ACTA PAEDIATRICA. 2011;100(7):e36-e39
Fifteen years of treatment with intravenous immunoglobulin in central nervous system Langerhans cell histiocytosis
Gavhed D; Laurencikas E; Akefeldt SO; Henter J-I
Editorial comment: LANCET. 2010;376(9758):2116
Cytotoxic therapy for severe swine flu A/H1N1
Henter J-I; Palmkvist-Kaijser K; Holzgraefe B; Bryceson YT; Palmer K
Letter: CLINICAL INFECTIOUS DISEASES. 2010;50(10):1426-1427
Evaluation of Parvovirus B19 Infection in Children with Malignant or Hematological Disorders
Gustafsson I; Kaldensjo T; Lindblom A; Norbeck O; Henter J-I; Tolfvenstam T; Broliden K
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2009;146(2):218-220
Multiple inherited sequence variations in two disease-causing genes in familial haemophagocytic lymphohistiocytosis
Rudd E; Meeths M; Uysal Z; Nordenskjoeld M; Henter J-I; Fadeel B
Letter: NATURE MEDICINE. 2009;15(5):484-485
Interleukin-17A is not expressed by CD207⁺ cells in Langerhans cell histiocytosis lesions reply
Arico M; Henter J-I; Egeler RM; Delprat C
Letter: LEUKEMIA. 2009;23(3):622-625
Survivin expression in the bone marrow of patients with severe congenital neutropenia
Carlsson G; Boxhammer S; Garwicz D; Henter JI; Palmblad J; Nordenskjold M; Porwit A; Fadeel B
Corrigendum: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(14):6023
Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome (vol 106, pg 468, 2008)
Chan C-B; Abe M; Hashimoto N; Hao C; Williams IR; Liu X; Nakao S; Yamamoto A; Zheng C; Henter J-I; Meeths M; Nordenskjold M; Li S-Y; Hara-Nishimura I; Asano M; Ye K
Editorial comment: PEDIATRIC BLOOD & CANCER. 2008;50(6):1127-1129
Pronounced hyperritinemia: Expanding the field of hemophagocytic lymphohistiocytosis
Henter J-I
Review: ACTA PAEDIATRICA. 2007;96(6):813-819
Kostmann syndrome or infantile genetic agranulocytosis, part two:: understanding the underlying genetic defects in severe congenital neutropenia
Carlsson G; Melin M; Dahl N; Ramme KG; Nordenskjold M; Palmblad J; Henter J-I; Fadeel B
Review: PEDIATRIC BLOOD & CANCER. 2007;48(2):124-131
HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis
Henter J-I; Horne A; Arico M; Egeler RM; Filipovich AH; Imashuku S; Ladisch S; McClain K; Webb D; Winiarski J; Janka G
Review: ACTA PAEDIATRICA. 2006;95(12):1526-1532
Kostmann syndrome or infantile genetic agranulocytosis, part one:: Celebrating 50 years of clinical and basic research on severe congenital neutropenia
Carlsson G; Andersson M; Putsep K; Garwicz D; Nordenskjold M; Henter J-I; Palmblad J; Fadeel B
Review: JOURNAL OF INTERNAL MEDICINE. 2006;260(1):1-10
A journey of hope:: lessons learned from studies on rare diseases and orphan drugs
Wästfelt M; Fadeel B; Henter J-I
Published conference paper: JOURNAL OF CLINICAL ONCOLOGY. 2005;23(36):9162-9171
Care-related distress:: A nationwide study of parents who lost their child to cancer
Kreicbergs U; Valdimarsdóttir U; Onelöv E; Björk O; Steineck G; Henter JI
Editorial comment: CLINICAL IMMUNOLOGY. 2005;117(2):121-124
Healing hemophagocytosis
Filipovich AH; Imashuku S; Henter JI; Sullivan KE
Letter: JOURNAL OF PEDIATRICS. 2005;146(1):151-152
Age-dependent differences in Nordic children with ITP
Rosthoj S; Hedlund-Treutiger I; Rajantie J; Zeller B; Jonsson OG; Henter JI
Letter: LEUKEMIA. 2005;19(1):159-161
Raji revisited:: cytogenetics of the original Burkitt's lymphoma cell line
Karpova MB; Schoumans J; Ernberg I; Henter JI; Nordenskjöld M; Fadeel B
Review: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. 2004;50(2):157-174
Histiocyte disorders
Henter JI; Tondini C; Pritchard J
Letter: TRENDS IN IMMUNOLOGY. 2003;24(8):409-410
Langerhans-cell histiocytosis: neoplasia or unbridled inflammation?
Fadeel B; Henter JI
Published conference paper: PEDIATRIC RESEARCH. 2003;54(1):30-36
Immunogenetic heterogeneity in single-system and multisystem Langerhans cell histiocytosis
Bernstrand C; Carstensen H; Jakobsen B; Svejgaard A; Henter JI; Olerup O
Letter: PRENATAL DIAGNOSIS. 2002;22(1):80-81
Prenatal diagnosis of perforin gene mutations in familial hemophagocytic lymphohistiocytosis (FHLH)
zur Stadt U; Pruggmayer M; Jung H; Henter JI; Schneider M; Kabisch H; Janka G
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2001;345(21):1577-1578
Successful treatment of Langerhans'-cell histiocytosis with etanercept
Henter JI; Karlén J; Calming U; Bernstrand C; Andersson U; Fadeel B
Review: LEUKEMIA & LYMPHOMA. 2001;42(1-2):13-20
Familial hemophagocytic lymphohistiocytosis: Too little cell death can seriously damage your health
Fadeel B; Orrenius S; Henter JI
Published conference paper: PEDIATRIC BLOOD & CANCER. 2000;35(5):462-467
Detection of langerhans cell histiocytosis lesions with somatostatin analogue scintigraphy - A preliminary report
Calming U; Jacobsson H; Henter JI
Review: LAKARTIDNINGEN. 2000;97(12):1405-1408
[Familial hemophagocytic lymphohistiocytosis: diagnosis, treatment and pathophysiological mechanisms].
Henter JI; Samuelsson A; Ericson K; Nilsson-Ardnor S; Elinder G; Fadeel B
Review: LAKARTIDNINGEN. 2000;97(12):1395-1402
[Apoptosis required for maintenance of homeostasis: familial hemophagocytic lymphohistiocytosis caused by too little cell death].
Fadeel B; Henter JI; Orrenius S
Editorial comment: EUROPEAN JOURNAL OF CANCER. 1999;35(5):767-769
The histiocytoses: The fall of the Tower of Babel - Commentary
Henter JI
Review: LEUKEMIA. 1996;10(2):197-203
Hemophagocytic lymphohistiocytosis. Report of 122 children from the international Registry
Arico M; Janka G; Fischer A; Henter JI; Blanche S; Elinder G; Martinetti M; Rusca MP
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 1995;91(3):774-775
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS - AN INHERITED PRIMARY FORM AND A REACTIVE SECONDARY FORM
HENTER JI; ELINDER G
Other: BONE MARROW TRANSPLANTATION. 1995;15(5):799-801
BONE-MARROW TRANSPLANTATION IN 2 CHILDREN WITH CONGENITAL AMEGAKARYOCYTIC THROMBOCYTOPENIA
HENTER JJ; WINIARSKI J; LJUNGMAN P; RINGDEN O; OST A
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Professor, Senior, Kvinnors och barns hälsa, Karolinska Institutet, 2024-2025
Professor, Kvinnors och barns hälsa, Karolinska Institutet, 2021-2024

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