Jacob Grünler
Anknuten till Forskning
E-postadress: jacob.grunler@ki.se
Besöksadress: Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, 17164 Solna
Postadress: K1 Molekylär medicin och kirurgi, K1 MMK Tillväxt & metabolism, 171 76 Stockholm
Forskningsbeskrivning
- Jacob Grünler is responsible for studies on inflammatory processes in
development of atherosclerosis in diabetics especially the effect of
antioxidants, like coenzyme Q10 and vitamin E.
These involves studies of cytokine production, studied in human blood
monocytes, lymfocytes and urine samples, animal models and HPLC-methodology,
flow-cytometry, cell culture studies.
He is also responsible for the laboratory environmental issues, animal
housing and ethic applications.
Forskargrupp Tillväxt och metabolism [1]
*Selected publications*
[pubmed:19057015]
[pubmed:15153069]
[pubmed:15038955]
[pubmed:14670990]
[pubmed:10437779]
[1] http://default/node/2970
Artiklar
- Article: EMBO REPORTS. 2024;25(4):1752-1772Zhao A; Jiang H; Palomares AR; Larsson A; He W; Grunler J; Zheng X; Wallberg KAR; Catrina S-B; Deng Q
- Article: MBIO. 2022;13(5):e0108622-e01022Teran G; Li H; Catrina S-B; Liu R; Brighenti S; Zheng X; Grunler J; Nylen S; Carow B; Rottenberg ME
- Article: ELIFE. 2022;11:e70714Zheng X; Narayanan S; Xu C; Eliasson Angelstig S; Grunler J; Zhao A; Di Toro A; Bernardi L; Mazzone M; Carmeliet P; Del Sole M; Solaini G; Forsberg EA; Zhang A; Brismar K; Schiffer TA; Rajamand Ekberg N; Botusan IR; Palm F; Catrina S-B
- Article: ISCIENCE. 2021;24(5):102494Zhang J; Teran G; Popa M; Madapura H; Ladds MJGW; Lianoudaki D; Grunler J; Arsenian-Henriksson M; McCormack E; Rottenberg ME; Catrina S-B; Lain S; Darekar S
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(3):659-671miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of KeratinocytesLi D; Peng H; Qu L; Sommar P; Wang A; Chu T; Li X; Bi X; Liu Q; Serezal IG; Rollman O; Lohcharoenkal W; Zheng X; Angelstig SE; Grunler J; Pivarcsi A; Sonkoly E; Catrina S-B; Xiao C; Stahle M; Mi Q-S; Zhou L; Landen NX
- Article: COMMUNICATIONS BIOLOGY. 2020;3(1):768Narayanan S; Angelstig SE; Xu C; Grunler J; Zhao A; Zhu W; Landen NX; Stahle M; Zhang J; Ivan M; Maltesen RG; Botusan IR; Ekberg NR; Zheng X; Catrina S-B
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(14):6985-6994Zheng X; Narayanan S; Sunkari VG; Eliasson S; Botusan IR; Grunler J; Catrina AI; Radtke F; Xu C; Zhao A; Ekberg NR; Lendahl U; Catrina S-B
- Article: PLOS ONE. 2018;13(3):e0193084Botusan IR; Zheng X; Narayanan S; Grunler J; Sunkari VG; Calissendorff FS; Ansurudeen I; Illies C; Svensson J; Jansson J-O; Ohlsson C; Brismar K; Catrina S-B
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
- Article: BBA CLINICAL. 2015;4:14-20Glutaredoxin mediated redox effects of coenzyme Q10 treatment in type 1 and type 2 diabetes patientsMontano SJ; Grunler J; Nair D; Tekle M; Fernandes AP; Hua X; Holmgren A; Brismar K; Ungerstedt JS
- Article: JOURNAL OF DIABETES AND ITS COMPLICATIONS. 2015;29(8):1152-1158Forsberg E; Xu C; Grunler J; Frostegard J; Tekle M; Brismar K; Karvestedt L
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(8):3008-3026Li D; Wang A; Liu X; Meisgen F; Gruenler J; Botusan IR; Narayanan S; Erikci E; Li X; Blomqvist L; Du L; Pivarcsi A; Sonkoly E; Chowdhury K; Catrina S-B; Stahle M; Landen NX
- Article: GROWTH HORMONE & IGF RESEARCH. 2015;25(1):34-40Brandt K; Grunler J; Brismar K; Wang J
- Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;177(2):478-482Brauner H; Luthje P; Grunler J; Ekberg NR; Dallner G; Brismar K; Brauner A
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(2):690-695Shi T-JS; Zhang M-D; Zeberg H; Nilsson J; Grunler J; Liu S-X; Xiang Q; Persson J; Fried KJ; Catrina SB; Watanabe M; Arhem P; Brismar K; Hokfelt TGM
- Article: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2011;27(5):470-479Savu O; Sunkari VG; Botusan IR; Gruenler J; Nikoshkov A; Catrina S-B
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(49):19426-19431Botusan IR; Sunkari VG; Savu O; Catrina AI; Grunler J; Lindberg S; Pereira T; Yla-Herttuala S; Poellinger L; Brismar K; Catrina S-B
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2008;283(30):21024-21035Skorupinska-Tudek K; Poznanski J; Wojcik J; Bienkowski T; Szostkiewicz I; Zelman-Femiak M; Bajda A; Chojnacki T; Olszowska O; Grunler J; Meyer O; Rohmer M; Danikiewicz W; Swiezewska E
- Article: BRITISH JOURNAL OF CANCER. 2005;92(8):1467-1474Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survivalCatrina SB; Lewitt M; Massambu C; Dricu A; Grünler J; Axelson M; Biberfeld P; Brismar K
- Article: BIOCHEMICAL JOURNAL. 2004;382(Pt 2):519-526Forsgren M; Attersand A; Lake S; Grünler J; Swiezewska E; Dallner G; Climent CL
- Article: ENDOCRINOLOGY. 2004;145(3):1137-1143Wang J; Grünler J; Lewitt MS
- Article: ANALYTICAL BIOCHEMISTRY. 2001;297(2):137-143Guan ZZ; Grünler J; Piao SF; Sindelar PJ
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(36):33297-33300Stenmark P; Grünler J; Mattsson J; Sindelar PJ; Nordlund P; Berthold DA
- Article: FEBS LETTERS. 1999;455(3):233-237Grünler J; Parmryd I
- Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 1998;353(2):191-198Bentinger M; Grünler J; Peterson E; Swiezewska E; Dallner G
- Article: FEBS LETTERS. 1995;358(3):230-232GRUNLER J; OLSSON JM; DALLNER G
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Alla övriga publikationer
- Editorial comment: ENDOCRINE. 2014;46(2):347-350Sunkari VG; Botusan IR; Savu O; Grunler J; Zheng X; Gustafsson J-A; Brismar K; Catrina S-B
- Published conference paper: AMINO ACIDS. 2012;43(1):127-134Ansurudeen I; Sunkari VG; Grunler J; Peters V; Schmitt CP; Catrina S-B; Brismar K; Forsberg EA
- Meeting abstract: CHEMISTRY AND PHYSICS OF LIPIDS. 2008;154:S41-S42Skorupinska-Tudek K; Poznanski J; Wojcik J; Bienkowski T; Szostkiewicz I; Zelman-Femiak M; Bajda A; Chojnacki T; Olszowska O; Grunler J; Meyer O; Rohmer M; Danikiewicz W; Swiezewska E
- Review: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2004;378:3-17Grünler J; Dallner G
Anställningar
- Anknuten till Forskning, Molekylär medicin och kirurgi, Karolinska Institutet, 2025-2028
- Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-2025