Ismael Valladolid Acebes

Publikationer
Populärvetenskap och samverkan

Artiklar

Journal article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2024;12:1380564
Western diet-induced ultrastructural changes in mouse pancreatic acinar cells
Lipovsek S; Dolensek J; Daris B; Valladolid-Acebes I; Vajs T; Leitinger G; Stozer A; Skelin Klemen M
Article: CELLULAR SIGNALLING. 2023;102:110535
ATF5 is a regulator of ER stress and β-cell apoptosis in different mouse models of genetic- and diet-induced obesity and diabetes mellitus
Ma J; Liu Y; Valladolid-Acebes I; Recio-Lopez P; Peng G; Li J; Berggren P-O; Juntti-Berggren L; Tong N
Article: BIOFACTORS. 2023;49(1):153-172
Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII
Recio-Lopez P; Valladolid-Acebes I; Hadwiger P; Hossbach M; Krampert M; Prata C; Berggren P-O; Juntti-Berggren L
Article: LIFE SCIENCE ALLIANCE. 2022;5(12):e202201505
Mitochondrial impairment and intracellular reactive oxygen species alter primary cilia morphology
Moruzzi N; Valladolid-Acebes I; Kannabiran SA; Bulgaro S; Burtscher I; Leibiger B; Leibiger IB; Berggren P-O; Brismar K
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;23(1):62
Apolipoprotein CIII Reduction Protects White Adipose Tissues against Obesity-Induced Inflammation and Insulin Resistance in Mice
Recio-Lopez P; Valladolid-Acebes I; Berggren P-O; Juntti-Berggren L
Article: SCIENCE ADVANCES. 2021;7(30):eabg5733
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
Adori C; Daraio T; Kuiper R; Barde S; Horvathova L; Yoshitake T; Ihnatko R; Valladolid-Acebes I; Vercruysse P; Wellendorf AM; Gramignoli R; Bozoky B; Kehr J; Theodorsson E; Cancelas JA; Mravec B; Jorns C; Ellis E; Mulder J; Uhlen M; Bark C; Hokfelt T
Article: ANTIOXIDANTS. 2021;10(7):1070
Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in db/db Mice
Dallner G; Bentinger M; Hussain S; Sinha I; Yang J; Schwank-Xu C; Zheng X; Swiezewska E; Brismar K; Valladolid-Acebes I; Tekle M
Article: METABOLITES. 2021;11(6):387
Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice
Leibiger B; Moede T; Valladolid-Acebes I; Paschen M; Visa M; Leibiger IB; Berggren P-O
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(10):4800-4813
Tissue-specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models
Moruzzi N; Lazzeri-Barcelo F; Valladolid-Acebes I; Moede T; Paschen M; Leibiger B; Berggren P-O; Leibiger IB
Article: SCIENCE ADVANCES. 2021;7(11):eabc2931
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements
Valladolid-Acebes I; Avall K; Recio-Lopez P; Moruzzi N; Bryzgalova G; Bjornholm M; Krook A; Alonso EF; Ericsson M; Landfors F; Nilsson SK; Berggren P-O; Juntti-Berggren L
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(4):1813
Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes
Mir-Coll J; Moede T; Paschen M; Neelakandhan A; Valladolid-Acebes I; Leibiger B; Biernath A; Ammala C; Leibiger IB; Yesildag B; Berggren P-O
Article: NEUROPHARMACOLOGY. 2020;170:108070
Existence of FGFR1-5-HT1AR heteroreceptor complexes in hippocampal astrocytes. Putative link to 5-HT and FGF2 modulation of hippocampal gamma oscillations
Narvaez M; Andrade-Talavera Y; Valladolid-Acebes I; Fredriksson M; Siegele P; Hernandez-Sosa A; Fisahn A; Fuxe K; Borroto-Escuela DO
Article: ROYAL SOCIETY OPEN SCIENCE. 2020;7(1):191171
Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic α-cells
Grubelnik V; Markovic R; Lipovsek S; Leitinger G; Gosak M; Dolensek J; Valladolid-Acebes I; Berggren P-O; Stozer A; Perc M; Marhl M
Article: THE FASEB JOURNAL. 2019;33(1):204-218
Diet-induced -cell insulin resistance results in reversible loss of functional -cell mass
Paschen M; Moede T; Valladolid-Acebes I; Leibiger B; Moruzzi N; Jacob S; Garcia-Prieto CF; Brismar K; Leibiger IB; Berggren P-O
Article: DIABETOLOGIA. 2019;62(1):123-135
Pleiotrophin deletion alters glucose homeostasis, energy metabolism and brown fat thermogenic function in mice
Sevillano J; Gracia Sanchez-Alonso M; Zapateria B; Calderon M; Alcala M; Limones M; Pita J; Gramage E; Vicente-Rodriguez M; Horrillo D; Medina-Gomez G; Jesus Obregon M; Viana M; Valladolid-Acebes I; Herradon G; Pilar Ramos-Alvarez M
Article: NEUROSCIENCE LETTERS. 2018;674:75-80
SNAP-25a and SNAP-25b differently mediate interactions with Munc18-1 and Gβγ subunits
Daraio T; Valladolid-Acebes I; Brismar K; Bark C
Article: SCIENTIFIC REPORTS. 2017;7(1):7744
SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca²⁺ oscillations in β cell networks
Daraio T; Bombek LK; Gosak M; Valladolid-Acebes I; Klemen MS; Refai E; Berggren P-O; Brismar K; Rupnik MS; Bark C
Article: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION. 2017;29(1):13-26
17β-Estradiol suppresses visceral adipogenesis and activates brown adipose tissue-specific gene expression.
Al-Qahtani SM; Bryzgalova G; Valladolid-Acebes I; Korach-André M; Dahlman-Wright K; Efendić S; Berggren P-O; Portwood N
Article: EUROPEAN JOURNAL OF NUTRITION. 2016;55(4):1615-1622
Decreased rates of operant food self-administration are associated with reward deficits in high-fat feeding mice
Ibias J; Miguens M; del Rio D; Valladolid-Acebes I; Stucchi P; Ambrosio E; Martin M; Morales L; Ruiz-Gayo M; Del Olmo N
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(31):E4326-E4335
Replacing SNAP-25b with SNAP-25a expression results in metabolic disease
Valladolid-Acebes I; Daraio T; Brismar K; Harkany T; Oegren SO; Hoekfelt TGM; Bark C
Article: NEUROREPORT. 2014;25(11):819-822
Morphological changes in glial fibrillary acidic protein immunopositive astrocytes in the hippocampus of dietary-induced obese mice.
Cano V; Valladolid-Acebes I; Hernández-Nuño F; Merino B; Del Olmo N; Chowen JA; Ruiz-Gayo M
Article: NEUROBIOLOGY OF LEARNING AND MEMORY. 2013;106:18-25
Spatial memory impairment and changes in hippocampal morphology are triggered by high-fat diets in adolescent mice. Is there a role of leptin?
Valladolid-Acebes I; Fole A; Martín M; Morales L; Cano MV; Ruiz-Gayo M; Del Olmo N
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2012;302(4):E396-E402
High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission.
Valladolid-Acebes I; Merino B; Principato A; Fole A; Barbas C; Lorenzo MP; García A; Del Olmo N; Ruiz-Gayo M; Cano V
Article: ENDOCRINOLOGY. 2012;153(2):690-699
Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway?
Stucchi P; Gil-Ortega M; Merino B; Guzmán-Ruiz R; Cano V; Valladolid-Acebes I; Somoza B; Le Gonidec S; Argente J; Valet P; Chowen JA; Fernández-Alfonso M; Ruiz-Gayo M
Article: PLOS ONE. 2012;7(5):e36139
Shift of circadian feeding pattern by high-fat diets is coincident with reward deficits in obese mice.
Morales L; Del Olmo N; Valladolid-Acebes I; Fole A; Cano V; Merino B; Stucchi P; Ruggieri D; López L; Alguacil LF; Ruiz-Gayo M
Article: NEUROBIOLOGY OF LEARNING AND MEMORY. 2011;95(1):80-85
High-fat diets impair spatial learning in the radial-arm maze in mice.
Valladolid-Acebes I; Stucchi P; Cano V; Fernández-Alfonso MS; Merino B; Gil-Ortega M; Fole A; Morales L; Ruiz-Gayo M; Del Olmo N
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Review: SEMINARS IN LIVER DISEASE. 2023;43(02):149-162
Hepatic Innervations and Nonalcoholic Fatty Liver Disease
Adori M; Bhat S; Gramignoli R; Valladolid-Acebes I; Bengtsson T; Uhlen M; Adori C
Conference publication: DIABETOLOGIA. 2023;66(SUPPL 1):S220-S221
Pleiotrophin: a new player in the morphology and functioning of the pancreas
Ballesteros-Pla C; Sevillano J; Sanchez-Alonso M; Limones M; Pita J; Pizarro Delgado J; Izquierdo A; Gomez GM; Valladolid-Acebes I; Herradon G; Alvarez MR
Book chapter: ELECTRON MICROSCOPY. 2022;p.
Application of Transmission Electron Microscopy to Detect Changes in Pancreas Physiology
Skelin Klemen M; Dolenšek J; Valladolid-Acebes I; Stožer A; Lipovšek S
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(2):932
Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle
Valladolid-Acebes I; Berggren P-O; Juntti-Berggren L
Conference publication: DIABETOLOGIA. 2021;64(SUPPL 1):96-97
An siRNA strategy to silence apolipoprotein CIII in the fight against the metabolic syndrome
Recio-Lopez P; Berggren P-O; Juntti-Berggren L; Valladolid-Acebes I
Book chapter: CO-IMMUNOPRECIPITATION METHODS FOR BRAIN TISSUE: NEUROMETHODS. 2019;p. 123-135
Isolation and Detection of G Protein-Coupled Receptor (GPCR) Heteroreceptor Complexes in Rat Brain Synaptosomal Preparation Using a Combined Brain Subcellular Fractionation/Co-immunoprecipitation (Co-IP) Procedures
Borroto-Escuela DO; Narvaez M; Zannoni M; Contri C; Crespo-Ramírez M; di Palma M; Ambrogini P; Borroto-Escuela DY; Brito I; Pita-Rodríguez M; Valladolid-Acebes I; de la Mora MP; Fuxe K
Conference publication: DIABETOLOGIA. 2019;62:S122
Insulin receptor isoform expression is altered in mouse tissues of genetic and dietary models of obesity and type 2 diabetes
Moruzzi N; Valladolid-Acebes I; Paschen M; Moede T; Leibiger B; Berggren P-O; Leibiger IB
Conference publication: DIABETOLOGIA. 2019;62:S71-S72
Apolipoprotein CIII in the human and the mouse brain: a potential link between metabolic diseases and neurodegenerative disorders
Valladolid-Acebes I; Recio-Lopez P; Berggren P-O; Juntti-Berggren L
Conference publication: DIABETOLOGIA. 2019;62:S293-S294
Apolipoprotein CIII silencing: a novel strategy to combat metabolic disorders
Recio-Lopez P; Berggren P-O; Juntti-Berggren L; Valladolid-Acebes I
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS IN THE CENTRAL NERVOUS SYSTEM: NEUROMETHODS. 2018;p. 15-23
Analysis and Quantification of GPCR Heteroreceptor Complexes and Their Allosteric Receptor–Receptor Interactions Using Radioligand Binding Autoradiography
Narvaez M; Corrales F; Brito I; Valladolid-Acebes I; Fuxe K; Borroto-Escuela DO
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS IN THE CENTRAL NERVOUS SYSTEM: NEUROMETHODS. 2018;p. 299-315
Detection, Analysis, and Quantification of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity Ligation Assay
Borroto-Escuela DO; Narvaez M; Valladolid-Acebes I; Shumilov K; Di Palma M; Wydra K; Schaefer T; Reyes-Resina I; Navarro G; Mudó G; Filip M; Sartini S; Friedland K; Schellekens H; Beggiato S; Ferraro L; Tanganelli S; Franco R; Belluardo N; Ambrogini P; Pérez de la Mora M; Fuxe K
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS IN THE CENTRAL NERVOUS SYSTEM: NEUROMETHODS. 2018;p. 283-298
Searching the GPCR Heterodimer Network (GPCR-hetnet) Database for Information to Deduce the Receptor–Receptor Interface and Its Role in the Integration of Receptor Heterodimer Functions
Brito I; Narvaez M; Savelli D; Shumilov K; Di Palma M; Sartini S; Skieterska K; Van Craenenbroeck K; Valladolid-Acebes I; Zaldivar-Oro R; Filip M; Cuppini R; Rivera A; Liu F; Ambrogini P; Pérez de la Mora M; Fuxe K; Borroto-Escuela DO
Conference publication: ACTA PHYSIOLOGICA. 2017;221:82
Western Diet-Induced Early Dysfunction of Mouse Pancreatic Beta Cells
Dolensek J; Valladolid-Acebes I; Gosak M; Klemen MS; Bombek LK; Pohorec V; Berggren PO; Brismar K; Stozer A; Rupnik MS
Conference publication: ACTA PHYSIOLOGICA. 2017;221:14
Investigating SNAP-25b (Synaptosomal-associated protein 25) function in mouse islet physiology beyond its classical role in membrane fusion
Daraio T; Bombek LK; Gosak M; Valladolid-Acebes I; Klemen MS; Refai E; Berggren PO; Brismar K; Rupnik MS; Bark C
Editorial comment: ADIPOCYTE. 2016;5(3):318-325
Minor differences in the molecular machinery mediating regulated membrane fusion has major impact on metabolic health
Valladolid-Acebes I; Daraio T; Brismar K; Hokfelt T; Bark C
Conference publication: DIABETOLOGIA. 2015;58:S293-S294
Western diet intervention modulates regulation of IGFBP-1 protein in C57/B16 mice
Ansurudeen I; Daraio T; Kolonelou C; Bark C; Brismar K; Valladolid-Acebes I
Conference publication: ACTA PHYSIOLOGICA. 2014;211:69
SNAP-25b-deficiency increases the vulnerability to diabesity and mood disorders
Valladolid-Acebes I; Daraio T; Brismar K; Ogren SO; Hokfelt T; Bark IC

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