Isabelle Magalhaes

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Publikationer
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Populärvetenskap och samverkan

Om mig

Docent i Immunologi, Karolinska Institutet
För mer information: https://staff.ki.se/people/isabelle-magalhaes

Artiklar

Journal article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2024;73(9):163
Impact of fludarabine and treosulfan on ovarian tumor cells and mesothelin chimeric antigen receptor T cells
El-Serafi I; Nilsson IM; Moter A; Duan Z; Mattsson J; Magalhaes I
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):273
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude
Poiret T; Vikberg S; Schoutrop E; Mattsson J; Magalhaes I
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: ONCOIMMUNOLOGY. 2022;11(1):2093426
Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality
Schoutrop E; Renken S; Micallef Nilsson I; Hahn P; Poiret T; Kiessling R; Wickstrom SL; Mattsson J; Magalhaes I
Article: SEMINARS IN CANCER BIOLOGY. 2022;86(Pt 3):207-223
Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment
Schoutrop E; Moyano-Galceran L; Lheureux S; Mattsson J; Lehti K; Dahlstrand H; Magalhaes I
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(6):e004458
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress
Renken S; Nakajima T; Magalhaes I; Mattsson J; Lundqvist A; Arner ESJ; Kiessling R; Wickstrom SL
Article: CANCER RESEARCH. 2021;81(11):3022-3035
Mesothelin-Specific CAR T Cells Target Ovarian Cancer
Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: ADVANCES IN THERAPY. 2020;37(12):5023-5031
Mesothelin Expression in Patients with High-Grade Serous Ovarian Cancer Does Not Predict Clinical Outcome But Correlates with CD11c⁺Expression in Tumor
Magalhaes I; Fernebro J; Abd Own S; Glaessgen D; Corvigno S; Remberger M; Mattsson J; Dahlstrand H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1300
Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines
Solders M; Gorchs L; Tiblad E; Gidlof S; Leeansyah E; Dias J; Sandberg JK; Magalhaes I; Lundell A-C; Kaipe H
Article: ONCOIMMUNOLOGY. 2019;8(2):e1535730
Immune profiling and identification of prognostic immune-related risk factors in human ovarian cancer
Radestad E; Klynning C; Stikvoort A; Mogensen O; Nava S; Magalhaes I; Uhlin M
Article: CYTOTHERAPY. 2018;20(7):941-951
Media evaluation for production and expansion of anti-CD19 chimeric antigen receptor T cells
Alnabhan R; Gaballa A; Mork L-M; Mattsson J; Uhlin M; Magalhaes I
Article: JOURNAL OF IMMUNOTHERAPY. 2018;41(2):73-83
CD19 Chimeric Antigen Receptor T Cells From Patients With Chronic Lymphocytic Leukemia Display an Elevated IFN- Production Profile
Magalhaes I; Kalland I; Kochenderfer JN; Osterborg A; Uhlin M; Mattsson J
Article: CLINICAL TRANSPLANTATION. 2017;31(8)
No effect of HLA-C mismatch after allogeneic hematopoietic stem cell transplantation with unrelated donors and T-cell depletion in patients with hematological malignancies
Magalhaes I; Uhlin M; Schaffer M; Sundin M; Hauzenberger D; Remberger M; Mattsson J
Article: SCIENTIFIC REPORTS. 2017;7(1):6123
MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation
Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2017;59:29-36
IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+monocytes
Rane L; Rahman S; Magalhaes I; Ambati A; Andersson J; Zumla A; Brighenti S; Maeurer MJ
Article: JOURNAL OF IMMUNOTHERAPY. 2017;40(4):132-139
A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer
Omazic B; Ayoglu B; Lohr M; Segersvard R; Verbeke C; Magalhaes I; Potacova Z; Mattsson J; Terman A; Ghazi S; Albiin N; Kartalis N; Nilsson P; Poiret T; Liu Z; Heuchel R; Schwenk JM; Permert J; Maeurer MJ; Ringden O
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861
Mucosal-associated invariant T cells Display a Poor reconstitution and altered Phenotype after allogeneic hematopoietic stem cell Transplantation
Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: ONCOTARGET. 2016;7(46):74686-74700
Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells
Misra S; Selvam AK; Wallenberg M; Ambati A; Matolcsy A; Magalhaes I; Lauter G; Bjornstedt M
Article: ONCOTARGET. 2016;7(21):30230-30240
Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning
Li Q; Rane L; Poiret T; Zou J; Magalhaes I; Ahmed R; Du Z; Vudattu N; Meng Q; Gustafsson-Jernberg A; Winiarski J; Ringden O; Maeurer M; Remberger M; Ernberg I
Article: IMMUNOLOGY. 2015;145(3):357-366
H1N1 viral proteome peptide microarray predicts individuals at risk for H1N1 infection and segregates infection versus Pandemrix vaccination
Ambati A; Valentini D; Montomoli E; Lapini G; Biuso F; Wenschuh H; Magalhaes I; Maeurer M
Article: TRANSPLANT INFECTIOUS DISEASE. 2015;17(3):371-379
Immunogenicity of virosomal adjuvanted trivalent influenza vaccination in allogeneic stem cell transplant recipients
Ambati A; Einarsdottir S; Magalhaes I; Poiret T; Bodenstein R; LeBlanc K; Brune M; Maeurer M; Ljungman P
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(4):1752-1762
Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
Magalhaes I; Pingris K; Poitou C; Bessoles S; Venteclef N; Kiaf B; Beaudoin L; Da Silva J; Allatif O; Rossjohn J; Kjer-Nielsen L; McCluskey J; Ledoux S; Genser L; Torcivia A; Soudais C; Lantz O; Boitard C; Aron-Wisnewsky J; Larger E; Clement K; Lehuen A
Article: FRONTIERS IN IMMUNOLOGY. 2015;6:341-7
iNKT and MAIT cell alterations in diabetes
Magalhaes I; Kiaf B; Lehuen A
Article: JOURNAL OF IMMUNOTHERAPY. 2014;37(8):416-425
TCR⁺CD4^-CD8^- T cells in Antigen-specific MHC Class I-restricted T-cell Responses After Allogeneic Hematopoietic Stem Cell Transplantation
Ahmed RK; Poiret T; Ambati A; Rane L; Remberger M; Omazic B; Vudattu NK; Winiarski J; Ernberg I; Axelsson-Robertson R; Magalhaes I; Castelli C; Ringden O; Maeurer M
Article: BMC IMMUNOLOGY. 2014;15:25
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults
Poiret T; Rane L; Remberger M; Omazic B; Gustafsson-Jernberg A; Vudattu NK; Ahmed R; Ernberg I; Winiarski J; Magalhaes I; Ringden O; Maeurer M
Article: BMC INFECTIOUS DISEASES. 2014;14:319
Difference in immune response in vaccinated and unvaccinated Swedish individuals after the 2009 influenza pandemic
Magalhaes I; Eriksson M; Linde C; Muhammad R; Rane L; Ambati A; Axelsson-Robertson R; Khalaj B; Alvarez-Corrales N; Lapini G; Montomoli E; Linde A; Pedersen NL; Maeurer M
Article: JOURNAL OF IMMUNOTHERAPY. 2013;36(8):432-441
Cord Blood T Cells Cultured With IL-7 in Addition to IL-2 Exhibit a Higher Degree of Polyfunctionality and Superior Proliferation Potential
Berglund S; Gertow J; Magalhaes I; Mattsson J; Uhlin M
Article: THORAX. 2013;68(3):269-276
BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
Ashenafi S; Aderaye G; Zewdie M; Raqib R; Bekele A; Magalhaes I; Lema B; Habtamu M; Rekha RS; Aseffa G; Maeurer M; Aseffa A; Svensson M; Andersson J; Brighenti S
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205:S301-S315
The Immunological Footprint of Mycobacterium tuberculosis T-cell Epitope Recognition
Axelsson-Robertson R; Magalhaes I; Parida SK; Zumla A; Maeurer M
Article: MOLECULAR MEDICINE. 2012;18(4):647-658
Prime-Boost Vaccination with rBCG/rAd35 Enhances CD8⁺ Cytolytic T-Cell Responses in Lesions from Mycobacterium Tuberculosis-Infected Primates
Rahman S; Magalhaes I; Rahman J; Ahmed RK; Sizemore DR; Scanga CA; Weichold F; Verreck F; Kondova I; Sadoff J; Thorstensson R; Spangberg M; Svensson M; Andersson J; Maeurer M; Brighenti S
Article: BMC INFECTIOUS DISEASES. 2012;12:41
Pattern recognition and cellular immune responses to novel Mycobacterium tuberculosis-antigens in individuals from Belarus
Ahmed RK; Rohava Z; Balaji KN; Hoffner SE; Gaines H; Magalhaes I; Zumla A; Skrahina A; Maeurer MJ
Article: JOURNAL OF GENERAL VIROLOGY. 2012;93(Pt 2):247-258
Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3
Pasetto A; Frelin L; Brass A; Yasmeen A; Koh S; Lohmann V; Bartenschlager R; Magalhaes I; Maeurer M; Sallberg M; Chen M
Article: GENES AND IMMUNITY. 2011;12(7):513-522
Increased (6 exon) interleukin-7 production after M. tuberculosis infection and soluble interleukin-7 receptor expression in lung tissue
Rane L; Rahman S; Magalhaes I; Ahmed R; Spangberg M; Kondova I; Verreck F; Andersson J; Brighenti S; Maeurer MJ
Article: IMMUNOLOGY. 2010;131(1):128-140
High content cellular immune profiling reveals differences between rhesus monkeys and men
Magalhaes I; Vudattu NK; Ahmed RK; Kuhlmann-Berenzon S; Ngo Y; Sizemore DR; Wehlin L; Weichold F; Andersson J; Skeiky YAW; Sadoff J; Gaines H; Thorstensson R; Spangberg M; Maeurer MJ
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2009;16(4):567-573
Major Histocompatibility Complex Class II Molecule-Human Immunodeficiency Virus Peptide Analysis Using a Microarray Chip
Gaseitsiwe S; Valentini D; Ahmed R; Mahdavifar S; Magalhaes I; Zerweck J; Schutkowski M; Gautherot E; Montero F; Ehrnst A; Reilly M; Maeurer M
Article: GENES AND IMMUNITY. 2009;10(2):132-140
Expression analysis and functional activity of interleukin-7 splice variants
Vudattu NK; Magalhaes I; Hoehn H; Pan D; Maeurer MJ
Article: JOURNAL OF IMMUNOTHERAPY. 2008;31(9):840-848
Tumor Antigen-specific T-cells are Present in the CD8αα⁺ T-cell Effector-memory Pool
Magalhaes I; Vudattu NK; Jaeger E; Maeurer MJ
Article: VIRUS RESEARCH. 2008;131(1):106-110
Human papillomavirus 16 E6, L1, L2 and E2 gene variants in cervical lesion progression
Lee K; Magalhaes I; Clavel C; Briolat J; Birembaut P; Tommasino M; Zehbe I
Article: PLOS ONE. 2008;3(12):e3840
Pattern Recognition in Pulmonary Tuberculosis Defined by High Content Peptide Microarray Chip Analysis Representing 61 Proteins from M. tuberculosis
Gaseitsiwe S; Valentini D; Mahdavifar S; Magalhaes I; Hoft DF; Zerweck J; Schutkowski M; Andersson J; Reilly M; Maeurer MJ
Article: PLOS ONE. 2008;3(11):e3790
rBCG Induces Strong Antigen-Specific T Cell Responses in Rhesus Macaques in a Prime-Boost Setting with an Adenovirus 35 Tuberculosis Vaccine Vector
Magalhaes I; Sizemore DR; Ahmed RK; Mueller S; Wehlin L; Scanga C; Weichold F; Schirru G; Pau MG; Goudsmit J; Kuhlmann-Berenzon S; Spangberg M; Andersson J; Gaines H; Thorstensson R; Skeiky YAW; Sadoff J; Maeurer M
Article: INTERNATIONAL JOURNAL OF CANCER. 2007;121(7):1512-1519
Reduced numbers of IL-7 receptor (CD127) expressing immune cells and IL-7-signaling defects in peripheral blood from patients with breast cancer
Vudattu NK; Magalhaes I; Schmidt M; Seyfert-Margolis V; Maeurer MJ
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Alla övriga publikationer

Preprint: BIORXIV. 2024
The CD4 T cell epigenetic JUNB+ state is associated with proliferation and exhaustion
Mihai IS; Selinger M; Boucheron N; Forsell M; Magalhaes I; Trygg J; Henriksson J
Review: METHODS IN MOLECULAR BIOLOGY. 2020;2098:3-21
MAIT Cells in Health and Disease.
Magalhaes I; Solders M; Kaipe H
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2019;19(8):811-827
Facing the future: challenges and opportunities in adoptive T cell therapy in cancer.
Magalhaes I; Carvalho-Queiroz C; Hartana CA; Kaiser A; Lukic A; Mints M; Nilsson O; Grönlund H; Mattsson J; Berglund S
Review: IMMUNOTHERAPY. 2019;11(4):335-345
Metabolic regulation of CAR T cell function by the hypoxic microenvironment in solid tumors
Schurich A; Magalhaes I; Mattsson J
Review: FRONTIERS IN IMMUNOLOGY. 2019;10:2309
The Metabolic Profile of Tumor and Virally Infected Cells Shapes Their Microenvironment Counteracting T Cell Immunity
Magalhaes I; Yogev O; Mattsson J; Schurich A
Review: EXPERT OPINION ON BIOLOGICAL THERAPY. 2017;17(6):691-699
Advances in umbilical cord blood cell therapy: the present and the future
Berglund S; Magalhaes I; Gaballa A; Vanherberghen B; Uhlin M
Other: MEDECINE/SCIENCES. 2015;31(8-9):717-719
MAIT cells in type 2 diabetes and obesity
Magalhaes I; Lehuen A
Letter: TRANSPLANTATION. 2014;98(12):E95-E96
Allogeneic Hematopoietic Cell Transplantation for GATA2 Deficiency in a Patient With Disseminated Human Papillomavirus Disease
Maeurer M; Magalhaes I; Andersson J; Ljungman P; Sandholm E; Uhlin M; Mattsson J; Ringden O
Review: CURRENT OPINION IN IMMUNOLOGY. 2014;27:83-88
Invariant NKT cell development: focus on NOD mice
Ghazarian L; Simoni Y; Magalhaes I; Lehuen A
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2010;40(5):1228-1231
Training in immunology of relevance to global health issues in resource poor settings
Parida SK; Magalhaes I; Dubois P; Janetzki S
Thesis / dissertation: 2009
CD8alpha/alpha+ T-cells and immune memory
Magalhaes, Isabelle
Meeting abstract: CLINICAL IMMUNOLOGY. 2006;119:S116-S117
Interleukin-7 receptor (IL-7R) mediated signaling effects in immune cells:novel readout for 'immune competence'
Vudattu N; Magalhaes I; Ahmed R; Schmidt M; Khademi M; Olsson T; Maeurer M
Meeting abstract: JOURNAL OF IMMUNOTHERAPY. 2005;28(6):632
Elevated antigen-specific IL2 production in CD8AA+T-cells in patients with melanoma responding to therapy
Magalhaes I; Vudattu NK; Karbach J; Juelch M; Castelli C; Jaeger E; Maeurer M
Meeting abstract: JOURNAL OF IMMUNOTHERAPY. 2005;28(6):626-627
Reduced expression of the IL-7 receptor (CD127) on CD8AA+T-cells and IL-7 signalling defects in patients with breast cancer
Vudattu NK; Magalhaes I; Schmidt M; Maeurer M

Anställningar

Anknuten till Forskning, Medicin, Huddinge, Karolinska Institutet, 2024-2026

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Docent, immunologi, Karolinska Institutet, 2021
Medicine Doktorsexamen, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2009

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