Hans-Gustaf Ljunggren

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Publikationer
CV
Populärvetenskap och samverkan

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Se profilsida på engelska

Artiklar

Journal article: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2025;10(1):253
Both inhibitory and activating KIRs recognize RIFINs: a dual-edged mechanism of NK cell control in malaria
Cuapio A; Ljunggren H-G
Journal article: JOURNAL OF HUMAN IMMUNITY. 2025;1(2):e20250029
Inborn errors of immunity affecting the MHC class I pathway for antigen presentation
Gadola SD; Ardeniz Ö; Cuapio A; Zimmer J; Ljunggren H-G
Article: PLOS NEGLECTED TROPICAL DISEASES. 2025;19(2):e0012693
Antigen-specific T cell responses following single and co-administration of tick-borne encephalitis, Japanese encephalitis, and yellow fever virus vaccines: Results from an open-label, non-randomized clinical trial-cohort
Wullimann D; Sandberg JT; Akber M; Lofling M; Gredmark-Russ S; Michaelsson J; Buggert M; Blom K; Ljunggren H-G
Article: GENES AND IMMUNITY. 2025;26(1):70-74
The HLA-B-21 M/T dimorphism associates with disease severity in COVID-19
Strunz B; Momayyezi P; Bilev E; Muvva JR; Chen P; Bister J; Schaffer M; Akber M; Cornillet M; Horowitz A; Malmberg K-J; Rooyackers O; Aleman S; Ljunggren H-G; Bjorkstrom NK; Stralin K; Hammer Q
Article: PLOS PATHOGENS. 2024;20(12):e1012755
Emerging mutation in SARS-CoV-2 facilitates escape from NK cell recognition and associates with enhanced viral fitness
Bilev E; Wild N; Momayyezi P; Sala BM; Sun R; Sandalova T; Marquardt N; Ljunggren H-G; Achour A; Hammer Q
Journal article: BLOOD. 2024;144:7234
Feasibility of Co-Administration of Autologous NK Cells and Anti-CD38 Monoclonal Antibody Isatuximab, in Multiple Myeloma Post-Autologous HSCT in a Randomized Phase 2 Clinical Trial
Lund J; Meinke S; Kashif M; Bohlin A; Lindberg EH; Ljunggren H-G; Alici E
Article: EBIOMEDICINE. 2024;109:105385
Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a two-year follow-up of the prospective clinical trial COVAXID
Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Gao Y; Soderdahl G; Osterborg A; Smith CIE; Vesterbacka J; Wullimann D; Cuapio A; Akber M; Bogdanovic G; Muschiol S; Aberg M; Lore K; Chen MS; Ljungman P; Buggert M; Aleman S; Ljunggren H-G
Article: BLOOD. 2024;144(8):873-887
Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis
Chiang SCC; Covill LE; Tesi B; Campbell TM; Schlums H; Nejati-Zendegani J; Mordrup K; Wood S; Theorell J; Sekine T; Al-Herz W; Akar HH; Belen FB; Chan MY; Devecioglu O; Aksu T; Ifversen M; Malinowska I; Sabel M; Unal E; Unal S; Introne WJ; Krzewski K; Gilmour KC; Ehl S; Ljunggren H-G; Nordenskjold M; Horne A; Henter J-I; Meeths M; Bryceson YT
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: SCIENTIFIC REPORTS. 2024;14(1):17820
Exploring the interplay between antiretroviral therapy and the gut-oral microbiome axis in people living with HIV
Narayanan A; Kieri O; Vesterbacka J; Manoharan L; Chen P; Ghorbani M; Ljunggren H-G; Chen MS; Aleman S; Soennerborg A; Ray S; Nowak P
Article: CELL HOST & MICROBE. 2024;32(2):156-161.e3
Memory T cells effectively recognize the SARS-CoV-2 hypermutated BA.2.86 variant
Muller TR; Gao Y; Wu J; Ribeiro O; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Soderdahl G; Smith CIE; Lore K; Chen MS; Ljungman P; Ingelman-Sundberg HM; Ljunggren H-G; Osterborg A; Sette A; Grifoni A; Aleman S; Buggert M
Article: JOURNAL OF IMMUNOLOGY. 2024;212(3):389-396
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies
Kammann T; Gorin J-B; Parrot T; Gao Y; Ponzetta A; Emgard J; Maleki KT; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Skagerberg M; Eriksson LI; Norrby-Teglund A; Mak JYW; Fairlie DP; Bjorkstrom NK; Klingstrom J; Ljunggren H-G; Aleman S; Buggert M; Stralin K; Sandberg JK
Article: CRYSTALS. 2024;14(12):1094
Crystallographic and NMR Study of Streptococcus pneumonia LCP Protein Psr_Sp Indicate the Importance of Dynamics in Four Long Loops for Ligand Specificity
Sandalova T; Sala BM; Moche M; Ljunggren H-G; Alici E; Henriques-Normark B; Agback T; Lesovoy D; Agback P; Achour A
Article: ONCOIMMUNOLOGY. 2023;12(1):2233402
Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8⁺ T cells towards the center of human lung tumors
Brownlie D; von Kries A; Valenzano G; Wild N; Yilmaz E; Safholm J; Al-Ameri M; Alici E; Ljunggren H-G; Schliemann I; Aricak O; de Flon FH; Michaelsson J; Marquardt N
Article: NPJ BIOFILMS AND MICROBIOMES. 2023;9(1):104
Impact of the gut microbiome on immunological responses to COVID-19 vaccination in healthy controls and people living with HIV
Ray S; Narayanan A; Vesterbacka J; Blennow O; Chen P; Gao Y; Gabarrini G; Ljunggren H-G; Buggert M; Manoharan L; Chen MS; Aleman S; Sonnerborg A; Nowak P
Article: SCIENCE IMMUNOLOGY. 2023;8(90):eadh0687
SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19
Cai C; Gao Y; Adamo S; Rivera-Ballesteros O; Hansson L; Osterborg A; Bergman P; Sandberg JK; Ljunggren H-G; Bjorkstrom NK; Stralin K; Llewellyn-Lacey S; Price DA; Qin C; Grifoni A; Weiskopf D; Wherry EJ; Sette A; Aleman S; Buggert M
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2023;114(5):507-512
NK cells in COVID-19-from disease to vaccination
Hammer Q; Cuapio A; Bister J; Bjoerkstroem NK; Ljunggren H-G
Article: JOURNAL OF HEMATOLOGY. 2023;12(4):170-175
Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia
Andersson M; Wu J; Wullimann D; Gao Y; Aberg M; Muschiol S; Healy K; Naud S; Bogdanovic G; Palma M; Mellstedt H; Chen P; Ljunggren H-G; Hansson L; Chen MS; Buggert M; Ingelman-Sundberg HM; Osterborg A
Article: EBIOMEDICINE. 2023;94:104700
Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a one-year follow-up of the prospective clinical trial COVAXID
Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; oesterborg A; Smith CIE; Vesterbacka J; Wullimann D; Cuapio A; Akber M; Bogdanovic G; Muschiol S; aberg M; Lore K; Chen MS; Buggert M; Ljungman P; Aleman S; Ljunggren H-G
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(6):1075-1082
SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Show Markedly Reduced Cross-reactivities Against Omicron Variants
Lindahl H; Chen P; Aberg M; Ljunggren H-G; Buggert M; Aleman S; Smith CIE; Bergman P
Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states
Muller TRR; Sekine T; Trubach D; Niessl J; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Olofsson A; Hernandez SPA; Gao Y; Cai C; Soderdahl G; Smith CIE; Osterborg A; Lore K; Sallberg Chen M; Ljungman P; Ljunggren H-G; Karlsson ACC; Saini SK; Aleman S; Buggert M
Article: CYTOTHERAPY. 2023;25(7):763-772
Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide
Karvouni M; Vidal-Manrique M; Susek KH; Hussain A; Gilljam M; Zhang Y; Gray JD; Lund J; Kaufmann G; Ljunggren H-G; Ji H; Lundqvist A; Wagner AK; Guo W; Alici E
Article: CELL HOST & MICROBE. 2023;31(6):928-936.e4
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox
Adamo S; Gao Y; Sekine T; Mily A; Wu J; Storgard E; Westergren V; Filen F; Sandberg JK; Sallberg M; Bergman P; Llewellyn-Lacey S; Ljunggren H-G; Price DA; Ekstrom A-M; Sette A; Grifoni A; Buggert M
Journal article: CYTOTHERAPY. 2023;25(6):s13-s14
13 Tissue Engineering: GENERATION OF UNIVERSAL CELLULAR GRAFTS UTILIZING SIGNALING-DEFICIENT MEMBRANE-BOUND CD45 ENGAGERS
Hussain A; Mohammad DK; Karvouni M; Hållstrand C; Gilljam M; Wagner AK; Ljunggren H; Alici E
Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(Supplement_1):75.16
Anamnestic expansion of Omicron-reactive CD8+ T cells after booster SARS-CoV-2 mRNA vaccination across different immunocompromised states
Müller TR; Sekine T; Trubach D; Niessl J; Olofsson A; Gao Y; Cai C; Nowak P; Blennow O; Hansson L; Mielke S; Bergman P; Ljunggren H-G; Karlsson AC; Saini SK; Aleman S; Buggert M
Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(Supplement_1):75.20
Pre-existing SARS-CoV-2-reactive CD4+ T cells are established and highly functional in early childhood
Olofsson A; Humbert M; Niessl J; Hodcroft E; Gao Y; Sohlberg E; Malmberg K-J; Lund-Johansen F; Björkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2023;72(5):1153-1167
Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy
Susek KH; Schwietzer YA; Karvouni M; Gilljam M; Keszei M; Hussain A; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner AK; Alici E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(12):e2220320120
Functional SARS-CoV-2 cross-reactive CD4⁺ T cells established in early childhood decline with age
Humbert M; Olofsson A; Wullimann D; Niessl J; Hodcroft EB; Cai C; Gao Y; Sohlberg E; Dyrdak R; Mikaeloff F; Neogi U; Albert J; Malmberg K-J; Lund-Johansen F; Aleman S; Bjorkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: RESPIRATORY RESEARCH. 2023;24(1):62
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Palma Medina LM; Babacic H; Dzidic M; Parke A; Garcia M; Maleki KT; Unge C; Lourda M; Kvedaraite E; Chen P; Muvva JR; Cornillet M; Emgard J; Moll K; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-JK; Sandberg J; Gredmark-Russ S; Rooyackers O; Svensson MJ; Chambers BI; Eriksson L; Pernemalm MK; Bjorkstrom N; Aleman S; Ljunggren H-G; Klingstrom J; Stralin K; Norrby-Teglund A
Article: PLOS NEGLECTED TROPICAL DISEASES. 2023;17(2):e0010616
Safety and immunogenicity following co-administration of Yellow fever vaccine with Tick-borne encephalitis or Japanese encephalitis vaccines: Results from an open label, non-randomized clinical trial.
Sandberg JT; Löfling M; Varnaitė R; Emgård J; Al-Tawil N; Lindquist L; Gredmark-Russ S; Klingström J; Loré K; Blom K; Ljunggren H-G
Article: PLOS ONE. 2023;18(12):e0295838
Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial
Sunden-Cullberg J; Chen P; Habel H; Skorup P; Janols H; Rasmuson J; Niward K; Balkhed AO; Chatzidionysiou K; Asgeirsson H; Blennow O; Parke A; Svensson A-K; Muvva JR; Ljunggren H-G; Horne A-C; Aden U; Henter J-I; Sonnerborg A; Vesterbacka J; Nowak P; Lampa J
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577
Adaptive single-KIR⁺NKG2C⁺ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
Haroun-Izquierdo A; Vincenti M; Netskar H; van Ooijen H; Zhang B; Bendzick L; Kanaya M; Momayyezi P; Li S; Wiiger MT; Hoel HJ; Krokeide SZ; Kremer V; Tjonnfjord G; Berggren S; Wikstroem K; Blomberg P; Alici E; Felices M; oenfelt B; Hoeglund P; Valamehr B; Ljunggren H-G; Bjoerklund A; Hammer Q; Kveberg L; Cichocki F; Miller JS; Malmberg K-J; Sohlberg E
Article: IMMUNITY. 2022;55(9):1732-1746.e5
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination
Gao Y; Cai C; Wullimann D; Niessl J; Rivera-Ballesteros O; Chen P; Lange J; Cuapio A; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Perez-Potti A; Sekine T; Muller TR; Boulouis C; Kammann T; Parrot T; Muvva JR; Sobkowiak M; Healy K; Bogdanovic G; Muschiol S; Soderdahl G; Osterborg A; Hellgren F; Grifoni A; Weiskopf D; Sette A; Lore K; Chen MS; Ljungman P; Sandberg JK; Smith CIE; Bergman P; Ljunggren H-G; Aleman S; Buggert M
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(6):1130-1136
Neutralizing SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Give Patients with X-Linked Agammaglobulinemia Limited Passive Immunity to the Omicron Variant
Lindahl H; Klingstrom J; Da Silva Rodrigues R; Christ W; Chen P; Ljunggren H-G; Buggert M; Aleman S; Smith CIE; Bergman P
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
The Karolinska KI/K COVID-19 immune atlas: An open resource for immunological research and educational purposes
Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
Journal article: HEMASPHERE. 2022;6(Suppl ):1326-1327
P1443: AUTOLOGOUS NK CELLS AS CONSOLIDATION AFTER FRONT-LINE STEM CELL TRANSPLANTATION IN MULTIPLE MYELOMA: A LONG-TERM FOLLOW-UP
Lund J; Nahi H; Meinke S; Holmqvist P-H; Ljunggren H-G; Aschan J; Alici E
Article: MOLECULAR MEDICINE. 2022;28(1):54
MAIT cell compartment characteristics are associated with the immune response magnitude to the BNT162b2 mRNA anti-SARS-CoV-2 vaccine
Boulouis C; Kammann T; Cuapio A; Parrot T; Gao Y; Mouchtaridi E; Wullimann D; Lange J; Chen P; Akber M; Ballesteros OR; Muvva JR; Smith CIE; Vesterbacka J; Kieri O; Nowak P; Bergman P; Buggert M; Ljunggren H-G; Aleman S; Sandberg JK
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(4):716-727
Elevated CD21^low B Cell Frequency Is a Marker of Poor Immunity to Pfizer-BioNTech BNT162b2 mRNA Vaccine Against SARS-CoV-2 in Patients with Common Variable Immunodeficiency
Bergman P; Wullimann D; Gao Y; Borgstrom EW; Norlin A-C; Enoksson SL; Aleman S; Ljunggren H-G; Buggert M; Smith CIE
Article: CELL REPORTS. 2022;38(10):110503
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; Garcia M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Degenhardt F; Franke A; Spallotta F; Mori M; Michaelsson J; Bjorkstrom NK; Rueckert T; Romagnani C; Horowitz A; Klingstrom J; Ljunggren H-G; Malmberg K-J
Article: NATURE MEDICINE. 2022;28(3):472-476
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant
Gao Y; Cai C; Grifoni A; Muller TR; Niessl J; Olofsson A; Humbert M; Hansson L; Osterborg A; Bergman P; Chen P; Olsson A; Sandberg JK; Weiskopf D; Price DA; Ljunggren H-G; Karlsson AC; Sette A; Aleman S; Buggert M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510
COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations
Cornillet M; Strunz B; Rooyackers O; Ponzetta A; Chen P; Muvva JR; Akber M; Buggert M; Chambers BJ; Dzidic M; Filipovic I; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Parrot T; Perez-Potti A; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Eriksson LI; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK
Article: CELL REPORTS MEDICINE. 2022;3(2):100508
Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma
Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellstrom K; Liwing J; Gustafsson C; Mansson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
Article: MED. 2022;3(2):137-153.e3
Salivary IgG to SARS-CoV-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals
Healy K; Pin E; Chen P; Soderdahl G; Nowak P; Mielke S; Hansson L; Bergman P; Smith CIE; Ljungman P; Valentini D; Blennow O; Osterborg A; Gabarrini G; Al-Manei K; Alkharaan H; Sobkowiak MJ; Yousef J; Mravinacova S; Cuapio A; Xu X; Akber M; Lore K; Hellstrom C; Muschiol S; Bogdanovic G; Buggert M; Ljunggren H-G; Hober S; Nilsson P; Aleman S; Chen MS
Article: MOLECULAR MEDICINE. 2022;28(1):20
NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals
Cuapio A; Boulouis C; Filipovic I; Wullimann D; Kammann T; Parrot T; Chen P; Akber M; Gao Y; Hammer Q; Strunz B; Potti AP; Ballesteros OR; Lange J; Muvva JR; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Soderdahl G; Osterborg A; Smith CIE; Bogdanovic G; Muschiol S; Hellgren F; Lore K; Sobkowiak MJ; Gabarrini G; Healy K; Chen MS; Alici E; Bjorkstrom NK; Buggert M; Ljungman P; Sandberg JK; Aleman S; Ljunggren H-G
Journal article: NATURE MEDICINE. 2022
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron
Gao Y; Cai C; Grifoni A; Müller TR; Niessl J; Olofsson A; Humbert M; Hansson L; Österborg A; Bergman P; Chen P; Olsson A; Sandberg JK; Weiskopf D; Price DA; Ljunggren H-G; Karlsson AC; Sette A; Aleman S; Buggert M
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079995
Persistence of salivary antibody responses after COVID-19 vaccination is associated with oral microbiome variation in both healthy and people living with HIV
Ghorbani M; Al-Manei K; Naud S; Healy K; Gabarrini G; Sobkowiak MJ; Chen P; Ray S; Akber M; Muschiol S; Bogdanovic G; Bergman P; Ljungman P; Buggert M; Ljunggren H-G; Pin E; Nowak P; Aleman S; Saellberg Chen M
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:834862
Comparison of Lung-Homing Receptor Expression and Activation Profiles on NK Cell and T Cell Subsets in COVID-19 and Influenza
Brownlie D; Rodahl I; Varnaite R; Asgeirsson H; Glans H; Falck-Jones S; Vangeti S; Buggert M; Ljunggren H-G; Michaelsson J; Gredmark-Russ S; Smed-Sorensen A; Marquardt N
Article: LAKARTIDNINGEN. 2021;118:21163
[Insights from creating a covid-19 biobank in Sweden].
Ljunggren H-G; Strålin K; Chen P; Cornillet M; Rooijackers O; I Eriksson L; Aleman S; Björkström N
Article: EBIOMEDICINE. 2021;74:103705
Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial
Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Chen P; Soderdahl G; Osterborg A; Smith CIE; Wullimann D; Vesterbacka J; Lindgren G; Blixt L; Friman G; Wahren-Borgstrom E; Nordlander A; Gomez AC; Akber M; Valentini D; Norlin A-C; Thalme A; Bogdanovic G; Muschiol S; Nilsson P; Hober S; Lore K; Chen MS; Buggert M; Ljunggren H-G; Ljungman P; Aleman S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of in COVID-19
Lourda M; Dzidic M; Hertwig L; Bergsten H; Medina LMP; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgard J; Moll K; Garcia M; Maleki KT; Klingstrom J; Michaelsson J; Flodstrom-Tullberg M; Brighenti S; Buggert M; Mjosberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sonnerborg A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ
Article: JOURNAL OF IMMUNOLOGY. 2021;207(4):1033-1043
Activation and Kinetics of Circulating T Follicular Helper Cells, Specific Plasmablast Response, and Development of Neutralizing Antibodies following Yellow Fever Virus Vaccination
Sandberg JT; Ols S; Lofling M; Varnait R; Lindgren G; Nilsson O; Rombo L; Kale M; Lore K; Blom K; Ljunggren H-G; Lindgren G; Nilsson O; Rombo L; Kale M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(11):e2016580118
Expansions of adaptive-like NK cells with a tissue-resident phenotype in human lung and blood
Brownlie D; Scharenberg M; Mold JE; Hard J; Kekalainen E; Buggert M; Nguyen S; Wilson JN; Al-Ameri M; Ljunggren H-G; Marquardt N; Michaelsson J
Article: CELL REPORTS MEDICINE. 2021;2(3):100220
MAIT cell activation is associated with disease severity markers in acute hantavirus infection
Maleki KT; Tauriainen J; Garcia M; Kerkman PF; Christ W; Dias J; Bystrom JW; Leeansyah E; Forsell MN; Ljunggren H-G; Ahlm C; Bjorkstrom NK; Sandberg JK; Klingstrom J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(6):e12997
Covid-19, SSI 50 years and Nobel: Three immunological reasons to remember 2020.
Höglund P; Ljunggren H-G; Jonsson R
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(6):751-754
Outcome of COVID-19 in multiple myeloma patients in relation to treatment
Susek KH; Gran C; Ljunggren H-G; Alici E; Nahi H
Article: JOURNAL OF IMMUNOLOGY. 2020;205(9):2437-2446
Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients
Varnaite R; Garcia M; Glans H; Maleki KT; Sandberg JT; Tynell J; Christ W; Lagerqvist N; Asgeirsson H; Ljunggren H-G; Ahlen G; Frelin L; Sallberg M; Blom K; Klingstrom J; Gredmark-Russ S
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: JOURNAL OF IMMUNOLOGY. 2020;204(4):914-922
Magnitude and Functional Profile of the Human CD4⁺ T Cell Response throughout Primary Immunization with Tick-Borne Encephalitis Virus Vaccine
Varnaite R; Blom K; Lampen MH; Vene S; Thunberg S; Lindquist L; Ljunggren H-G; Rombo L; Askling HH; Gredmark-Russ S
Article: PLOS PATHOGENS. 2020;16(2):e1008297
Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2
Sola-Riera C; Garcia M; Ljunggren H-G; Klingstrom J
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2020;9(12):e1224
Innate lymphoid cell composition associates with COVID-19 disease severity
Garcia M; Kokkinou E; Carrasco Garcia A; Parrot T; Palma Medina LM; Maleki KT; Christ W; Varnaite R; Filipovic I; Ljunggren H-G; Bjorkstrom NK; Folkesson E; Rooyackers O; Eriksson LI; Sonnerborg A; Aleman S; Stralin K; Gredmark-Russ S; Klingstrom J; Mjosberg J
Article: JOURNAL OF IMMUNOLOGY. 2019;203(8):2210-2221
Terminal Effector CD8 T Cells Defined by an IKZF2⁺IL-7R^- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity
Naluyima P; Lal KG; Costanzo MC; Kijak GH; Gonzalez VD; Blom K; Eller LA; Creegan M; Hong T; Kim D; Quinn TC; Bjorkstrom NK; Ljunggren H-G; Serwadda D; Katabira ET; Sewankambo NK; Gray RH; Baeten JM; Michael NL; Wabwire-Mangen F; Robb ML; Bolton DL; Sandberg JK; Eller MA
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2019;49(10):1457-1973
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
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Article: NATURE COMMUNICATIONS. 2019;10(1):3897
NK cells are activated and primed for skin-homing during acute dengue virus infection in humans
Zimmer CL; Cornillet M; Sola-Riera C; Cheung K-W; Ivarsson MA; Lim MQ; Marquardt N; Leo Y-S; Lye DC; Klingstrom J; MacAry PA; Ljunggren H-G; Rivino L; Bjorkstrom NK
Article: NATURE COMMUNICATIONS. 2019;10(1):3841
Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells
Marquardt N; Kekalainen E; Chen P; Lourda M; Wilson JN; Scharenberg M; Bergman P; Al-Ameri M; Hard J; Mold JE; Ljunggren H-G; Michaelsson J
Article: CELL REPORTS. 2019;28(8):2124-2139.e6
Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5
Sola-Riera C; Gupta S; Maleki KT; Gonzalez-Rodriguez P; Saidi D; Zimmer CL; Vangeti S; Rivino L; Leo Y-S; Lye DC; MacAry PA; Ahlm C; Smed-Sorensen A; Joseph B; Bjorkstrom NK; Ljunggren H-G; Klingstrom J
Article: JOURNAL OF HEPATOLOGY. 2019;71(2):301-312
Chronic hepatitis delta virus infection leads to functional impairment and severe loss of MAIT cells
Dias J; Hengst J; Parrot T; Leeansyah E; Lunemann S; Malone DFG; Hardtke S; Strauss O; Zimmer CL; Berglin L; Schirdewahn T; Ciesek S; Marquardt N; von Hahn T; Manns MP; Cornberg M; Ljunggren H-G; Wedemeyer H; Sandberg JK; Bjorkstrom NK
Article: JOURNAL OF INFECTIOUS DISEASES. 2019;219(11):1832-1840
Serum Markers Associated with Severity and Outcome of Hantavirus Pulmonary Syndrome
Maleki KT; Garcia M; Iglesias A; Alonso D; Ciancaglini M; Hammar U; Ljunggren H-G; Schierloh P; Martinez VP; Klingstrom J
Article: JOURNAL OF INTERNAL MEDICINE. 2019;285(5):510-523
Innate and adaptive immune responses against human Puumala virus infection: immunopathogenesis and suggestions for novel treatment strategies for severe hantavirus-associated syndromes
Klingstrom J; Smed-Sorensen A; Maleki KT; Sola-Riera C; Ahlm C; Bjorkstrom NK; Ljunggren HG
Article: SCIENTIFIC REPORTS. 2019;9(1):834
Orthohantaviruses belonging to three phylogroups all inhibit apoptosis in infected target cells
Sola-Riera C; Gupta S; Ljunggren H-G; Klingstrom J
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1116
Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells
Scharenberg M; Vangeti S; Kekalainen E; Bergman P; Al-Ameri M; Johansson N; Sonden K; Falck-Jones S; Farnert A; Ljunggren H-G; Michaelsson J; Smed-Sorensen A; Marquardt N
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;88(6):e12731
Seminal immunologic discoveries with direct clinical implications: The 2018 Nobel Prize in Physiology or Medicine honours discoveries in cancer immunotherapy.
Ljunggren H-G; Jonsson R; Höglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(9):1456-1469
Proteome analysis of human CD56^neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56^dim NK cells
Voigt J; Malone DFG; Dias J; Leeansyah E; Bjorkstrom NK; Ljunggren H-G; Groebe L; Klawonn F; Heyner M; Sandberg JK; Jaensch L
Article: IMMUNOHORIZONS. 2018;2(6):172-184
Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.
Lampen MH; Uchtenhagen H; Blom K; Varnaitė R; Pakalniene J; Dailidyte L; Wälchli S; Lindquist L; Mickiene A; Michaëlsson J; Schumacher TN; Ljunggren H-G; Sandberg JK; Achour A; Gredmark-Russ S
Article: NATURE COMMUNICATIONS. 2018;9(1):2275
Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity
Strunz B; Hengst J; Deterding K; Manns MP; Cornberg M; Ljunggren H-G; Wedemeyer H; Bjorkstrom NK
Article: CLINICAL CANCER RESEARCH. 2018;24(8):1834-1844
Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
Bjorklund AT; Carlsten M; Sohlberg E; Liu LL; Clancy T; Karimi M; Cooley S; Miller JS; Klimkowska M; Schaffer M; Watz E; Wikstrom K; Blomberg P; Wahlin BE; Palma M; Hansson L; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2017;47(8):1280-1294
Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers
Forkel M; Berglin L; Kekalainen E; Carlsson A; Svedin E; Michaelsson J; Nagasawa M; Erjefalt JS; Mori M; Flodstrom-Tullberg M; Bergquist A; Ljunggren H-G; Westgren M; Lindforss U; Friberg D; Jorns C; Ellis E; Bjorkstrom NK; Mjosberg J
Article: JOURNAL OF AUTOIMMUNITY. 2017;81:1-12
Contribution of inhibitory receptor TIGIT to NK cell education
He Y; Peng H; Sun R; Wei H; Ljunggren H-G; Yokoyama WM; Tian Z
Article: PLOS PATHOGENS. 2017;13(6):e1006462
Human hantavirus infection elicits pronounced redistribution of mononuclear phagocytes in peripheral blood and airways
Scholz S; Baharom F; Rankin G; Maleki KT; Gupta S; Vangeti S; Pourazar J; Discacciati A; Hoijer J; Bottai M; Bjorkstrom NK; Rasmuson J; Evander M; Blomberg A; Ljunggren H-G; Klingstrom J; Ahlm C; Smed-Sorensen A
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:525
Cytomegalovirus-Driven Adaptive-Like Natural Killer Cell Expansions Are Unaffected by Concurrent Chronic Hepatitis Virus Infections
Malone DFG; Lunemann S; Hengst J; Ljunggren H-G; Manns MP; Sandberg JK; Cornberg M; Wedemeyer H; Bjorkstrom NK
Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(Supplement_1):78.25
HIV-induced modifications of TIGIT expression impair CD8 T cell polyfunctionality
Scharf L; Tauriainen J; Frederiksen J; Naji A; Ljunggren H-G; Sönnerborg A; Lund O; Reyes-Terán G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1321-1330.e4
Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69^-CD56^dim cells
Marquardt N; Kekalainen E; Chen P; Kvedaraite E; Wilson JN; Ivarsson MA; Mjosberg J; Berglin L; Safholm J; Manson ML; Adner M; Al-Ameri M; Bergman P; Orre A-C; Svensson M; Dahlen B; Dahlen S-E; Ljunggren H-G; Michaelsson J
Article: SCIENTIFIC REPORTS. 2017;7:40354
Perturbed CD8⁺ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
Tauriainen J; Scharf L; Frederiksen J; Naji A; Ljunggren H-G; Sonnerborg A; Lund O; Reyes-Teran G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:426
Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak-Higashi Syndrome Patients
Chiang SCC; Wood SM; Tesi B; Akar HH; Al-Herz W; Ammann S; Belen FB; Caliskan U; Kaya Z; Lehmberg K; Patiroglu T; Tokgoz H; Unuvar A; Introne WJ; Henter J-I; Nordenskjold M; Ljunggren H-G; Meeths M; Ehl S; Krzewski K; Bryceson YT
Journal article: ZEITSCHRIFT FUR GASTROENTEROLOGIE. 2016;54(12):1343-1404
NK cell responses during direct-acting antiviral treatment of chronic hepatitis C virus infection
Hengst J; Strunz B; Deterding K; Schlaphoff V; Manns M; Ljunggren H; Björkström N; Wedemeyer H
Article: JOURNAL OF IMMUNOLOGY. 2016;197(7):2762-2771
NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection
Blom K; Braun M; Pakalniene J; Lunemann S; Enqvist M; Dailidyte L; Schaffer M; Lindquist L; Mickiene A; Michaelsson J; Ljunggren H-G; Gredmark-Russ S
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(9):2204-2210
Nonreversible MAIT cell-dysfunction in chronic hepatitis C virus infection despite successful interferon-free therapy
Hengst J; Strunz B; Deterding K; Ljunggren H-G; Leeansyah E; Manns MP; Cornberg M; Sandberg JK; Wedemeyer H; Bjorkstrom NK
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769
In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation
Lakshmikanth T; Heuts F; Muvva SSVJR; Wallin RPA; Persson A-K; Fauriat C; Applequist SE; Ljunggren H-G; Hoglund P; Karre K; Svensson M; Juarez JG
Article: CELL REPORTS. 2016;15(5):1088-1099
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Liu LL; Landskron J; Ask EH; Enqvist M; Sohlberg E; Traherne JA; Hammer Q; Goodridge JP; Larsson S; Jayaraman J; Oei VYS; Schaffer M; Tasken K; Ljunggren H-G; Romagnani C; Trowsdale J; Malmberg K-J; Beziat V
Article: JOURNAL OF IMMUNOLOGY. 2016;196(3):1400-1411
Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
Bjorklund AT; Clancy T; Goodridge JP; Beziat V; Schaffer M; Hovig E; Ljunggren H-G; Ljungman PT; Malmberg K-J
Article: FRONTIERS IN IMMUNOLOGY. 2015;6:507
Polyclonal expansion of NKG2C⁺ NK cells in TAP-deficient patients
Beziat V; Sleiman M; Goodridge JP; Kaarbo M; Liu LL; Rollag H; Ljunggren H-G; Zimmer J; Malmberg K-J
Article: IMMUNITY. 2015;42(3):443-456
Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
Schlums H; Cichocki F; Tesi B; Theorell J; Beziat V; Holmes TD; Han H; Chiang SCC; Foley B; Mattsson K; Larsson S; Schaffer M; Malmberg K-J; Ljunggren H-G; Miller JS; Bryceson YT
Article: JOURNAL OF IMMUNOLOGY. 2015;194(6):2467-2471
Cutting Edge: Identification and Characterization of Human Intrahepatic CD49a⁺ NK Cells
Marquardt N; Beziat V; Nystrom S; Hengst J; Ivarsson MA; Kekalainen E; Johansson H; Mjosberg J; Westgren M; Lankisch TO; Wedemeyer H; Ellis EC; Ljunggren H-G; Michaelsson J; Bjorkstrom NK
Article: GUT. 2015;64(3):469-482
Effects of HDV infection and pegylated interferon a treatment on the natural killer cell compartment in chronically infected individuals
Lunemann S; Malone DFG; Grabowski J; Port K; Beziat V; Bremer B; Malmberg K-J; Manns MP; Sandberg JK; Cornberg M; Ljunggren H-G; Wedemeyer H; Bjorkstrom NK
Article: PLOS PATHOGENS. 2015;11(1):e1004622
Specificity and Dynamics of Effector and Memory CD8 T Cell Responses in Human Tick-Borne Encephalitis Virus Infection
Blom K; Braun M; Pakalniene J; Dailidyte L; Beziat V; Lampen MH; Klingstrom J; Lagerqvist N; Kjerstadius T; Michaelsson J; Lindquist L; Ljunggren H-G; Sandberg JK; Mickiene A; Gredmark-Russ S
Journal article: BLOOD. 2014;124(21):1120
Early and Transient Microchimerism Associated with Complete Remission after Adoptively Transferred Haploidentical NK Cells Against High Risk Myelodysplastic Syndrome and Refractory Acute Myeloid Leukemia
Bjorklund AT; Carlsten M; Schaffer M; Liu L; Cooley SA; Miller JS; Watz E; Palma M; Hansson L; Wahlin BE; Mollgard L; Hagglund H; Blomberg P; Ljungman PT; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
Article: PLOS PATHOGENS. 2014;10(11):e1004521
NK Cell Activation in Human Hantavirus Infection Explained by Virus-Induced IL-15/IL15Rα Expression
Braun M; Bjorkstrom NK; Gupta S; Sundstrom K; Ahlm C; Klingstrom J; Ljunggren H-G
Article: CLINICAL INFECTIOUS DISEASES. 2014;59(8):1130-1132
Increased Risk for Lymphoma Following Hemorrhagic Fever With Renal Syndrome
Klingstrom J; Granath F; Ekbom A; Bjorkstrom NK; Ljunggren H-G
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2014;63(6):627-641
Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation
Theorell J; Gustavsson A-L; Tesi B; Sigmundsson K; Ljunggren H-G; Lundbaeck T; Bryceson YT
Article: JOURNAL OF INFECTIOUS DISEASES. 2014;209(9):1362-1373
Compromised Function of Natural Killer Cells in Acute and Chronic Viral Hepatitis
Lunemann S; Malone DFG; Hengst J; Port K; Grabowski J; Deterding K; Markova A; Bremer B; Schlaphoff V; Cornberg M; Manns MP; Sandberg JK; Ljunggren H-G; Bjorkstrom NK; Wedemeyer H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(2):90-97
Angiostatic Effects of NK Cell-Derived IFN-γ Counteracted by Tumour Cell Bcl-x_L Expression
Wallin RPA; Sundquist VS; Brakenhielm E; Cao Y; Ljunggren H-G; Grandien A
Journal article: JOURNAL OF IMMUNOLOGY. 2013;190(Supplement_1):117.3
Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response (P1406)
Blom K; Braun M; Ivarsson M; Gonzalez V; Falconer K; Moll M; Ljunggren H-G; Michaelsson J; Sandberg J
Journal article: JOURNAL OF IMMUNOLOGY. 2013;190(Supplement_1):117.9
CD8 T cells express randomly selected KIRs with distinct specificities compared to NK cells (P1418)
Björkström N; Beziat V; Cichocki F; Liu L; Levine J; Larsson S; Koup R; Anderson S; Ljunggren H-G; Malmberg K-J
Article: BLOOD. 2013;121(14):2678-2688
NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
Beziat V; Liu LL; Malmberg J-A; Ivarsson MA; Sohlberg E; Bjorklund AT; Retiere C; Sverremark-Ekstrom E; Traherne J; Ljungman P; Schaffer M; Price DA; Trowsdale J; Michaelsson J; Ljunggren H-G; Malmberg K-J
Article: JOURNAL OF IMMUNOLOGY. 2013;190(5):2150-2158
Temporal Dynamics of the Primary Human T Cell Response to Yellow Fever Virus 17D As It Matures from an Effector- to a Memory-Type Response
Blom K; Braun M; Ivarsson MA; Gonzalez VD; Falconer K; Moll M; Ljunggren H-G; Michaelsson J; Sandberg JK
Article: PLOS PATHOGENS. 2013;9(3):e1003272
Hantavirus-infection Confers Resistance to Cytotoxic Lymphocyte-Mediated Apoptosis
Gupta S; Braun M; Tischler ND; Stoltz M; Sundstrom KB; Bjorkstrom NK; Ljunggren H-G; Klingstrom J
Article: BLOOD. 2013;121(8):1345-1356
Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production
Chiang SCC; Theorell J; Entesarian M; Meeths M; Mastafa M; Al-Herz W; Frisk P; Gilmour KC; Ifversen M; Langenskiold C; Machaczka M; Naqvi A; Payne J; Perez-Martinez A; Sabel M; Unal E; Unal S; Winiarski J; Nordenskjold M; Ljunggren H-G; Henter J-I; Bryceson YT
Journal article: ZEITSCHRIFT FUR GASTROENTEROLOGIE. 2013;51(01)
Comprehensive phenotyping of natural killer cells in acute and chronic viral hepatitis
Lunemann S; Malone D; Schlaphoff V; Manns M; Sandberg J; Cornberg M; Ljunggren H; Björkström N; Wedemeyer H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2012;76(6):559-566
NK Cells Inhibit T-bet-deficient, Autoreactive Th17 Cells
Wu W; Shi S; Ljunggren H-G; Cava AL; Van Kaer L; Shi F-D; Liu R
Article: BLOOD. 2012;120(17):3455-3465
CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells
Bjorkstrom NK; Beziat V; Cichocki F; Liu LL; Levine J; Larsson S; Koup RA; Anderson SK; Ljunggren H-G; Malmberg K-J
Article: JOURNAL OF INFECTIOUS DISEASES. 2012;205(9):1351-1362
Interferon α-Stimulated Natural Killer Cells From Patients With Acute Hepatitis C Virus (HCV) Infection Recognize HCV-Infected and Uninfected Hepatoma Cells via DNAX accessory molecule-1
Stegmann KA; Bjorkstrom NK; Ciesek S; Lunemann S; Jaroszewicz J; Wiegand J; Malinski P; Dustin LB; Rice CM; Manns MP; Pietschmann T; Cornberg M; Ljunggren H-G; Wedemeyer H
Article: PLOS ONE. 2012;7(1):e29672
Kinome Analysis of Receptor-Induced Phosphorylation in Human Natural Killer Cells
Koenig S; Nimtz M; Scheiter M; Ljunggren H-G; Bryceson YT; Jaensch L
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2011;74(6):521
2011 Nobel Prize in Physiology or Medicine to three immunologists.
Jonsson R; Ljunggren H-G
Journal article: NATURE REVIEWS IMMUNOLOGY. 2011;11(12):880
Erratum: Organ-specific features of natural killer cells
Shi F-D; Ljunggren H-G; La Cava A; Van Kaer L
Article: BLOOD. 2011;118(22):5783-5793
Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in UNC13D
Meeths M; Chiang SCC; Wood SM; Entesarian M; Schlums H; Bang B; Nordenskjold E; Bjorklund C; Jakovljevic G; Jazbec J; Hasle H; Holmqvist B-M; Rajic L; Pfeifer S; Rosthoj S; Sabel M; Salmi TT; Stokland T; Winiarski J; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I; Bryceson YT
Article: JOURNAL OF VIROLOGY. 2011;85(19):10252-10260
Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection
Lindgren T; Ahlm C; Mohamed N; Evander M; Ljunggren H-G; Bjorkstrom NK
Article: JOURNAL OF IMMUNOLOGY. 2011;187(7):3546-3554
Selenite Induces Posttranscriptional Blockade of HLA-E Expression and Sensitizes Tumor Cells to CD94/NKG2A-Positive NK Cells
Enqvist M; Nilsonne G; Hammarfjord O; Wallin RPA; Bjoerkstroem NK; Bjornstedt M; Hjerpe A; Ljunggren H-G; Dobra K; Malmberg K-J; Carlsten M
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(7):1913-1923
NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
Kuylenstierna C; Bjorkstrom NK; Andersson SK; Sahlstrom P; Bosnjak L; Paquin-Proulx D; Malmberg K-J; Ljunggren H-G; Moll M; Sandberg JK
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2011;208(1):13-21
Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
Bjorkstrom NK; Lindgren T; Stoltz M; Fauriat C; Braun M; Evander M; Michaelsson J; Malmberg K-J; Klingstrom J; Ahlm C; Ljunggren H-G
Article: PLOS ONE. 2011;6(11):e27664
Characterization of Natural Killer Cell Phenotype and Function during Recurrent Human HSV-2 Infection
Bjorkstrom NK; Svensson A; Malmberg K-J; Eriksson K; Ljunggren H-G
Article: BLOOD. 2010;116(19):3853-3864
Expression patterns of NKG2A, KIR, and CD57 define a process of CD56^dim NK-cell differentiation uncoupled from NK-cell education
Bjorkstrom NK; Riese P; Heuts F; Andersson S; Fauriat C; Ivarsson MA; Bjorklund AT; Flodstrom-Tullberg M; Michaelsson J; Rottenberg ME; Guzman CA; Ljunggren H-G; Malmberg K-J
Article: LEUKEMIA. 2010;24(9):1607-1616
Reduced DNAM-1 expression on bone marrow NK cells associated with impaired killing of CD34⁺ blasts in myelodysplastic syndrome
Carlsten M; Baumann BC; Simonsson M; Jadersten M; Forsblom A-M; Hammarstedt C; Bryceson YT; Ljunggren H-G; Hellstrom-Lindberg E; Malmberg K-J
Journal article: ZEITSCHRIFT FUR GASTROENTEROLOGIE. 2010;48(08)
IFN-alpha activated NK cells require DNAM-1 for recognition of infected cells during acute HCV infection
Stegmann K; Björkström N; Wiegand J; Malinski P; Manns M; Ljunggren H; Wedemeyer H
Article: GASTROENTEROLOGY. 2010;138(5):1885-1U68
Interferon-α-Induced TRAIL on Natural Killer Cells Is Associated With Control of Hepatitis C Virus Infection
Stegmann KA; Bjorkstrom NK; Veber H; Ciesek S; Riese P; Wiegand J; Hadem J; Suneetha PV; Jaroszewicz J; Wang C; Schlaphoff V; Fytili P; Cornberg M; Manns MP; Geffers R; Pietschmann T; Guzman CA; Ljunggren H-G; Wedemeyer H
Article: BLOOD. 2010;115(13):2686-2694
NK cells expressing inhibitory KIR for non-self-ligands remain tolerant in HLA-matched sibling stem cell transplantation
Bjorklund AT; Schaffer M; Fauriat C; Ringden O; Remberger M; Hammarstedt C; Barrett AJ; Ljungman P; Ljunggren H-G; Malmberg K-J
Article: PEDIATRIC BLOOD & CANCER. 2010;54(4):563-572
Clinical Presentation of Griscelli Syndrome Type 2 and Spectrum of RAB27A Mutations
Meeths M; Bryceson YT; Rudd E; Zheng C; Wood SM; Ramme K; Beutel K; Hasle H; Heilmann C; Hultenby K; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: BLOOD. 2010;115(11):2167-2176
Regulation of human NK-cell cytokine and chemokine production by target cell recognition
Fauriat C; Long EO; Ljunggren H-G; Bryceson YT
Article: BLOOD. 2010;115(6):1166-1174
Education of human natural killer cells by activating killer cell immunoglobulin-like receptors
Fauriat C; Ivarsson MA; Ljunggren H-G; Malmberg K-J; Michaelsson J
Article: METHODS IN MOLECULAR BIOLOGY. 2010;612:335-352
Functional analysis of human NK cells by flow cytometry.
Bryceson YT; Fauriat C; Nunes JM; Wood SM; Björkström NK; Long EO; Ljunggren H-G
Article: METHODS IN MOLECULAR BIOLOGY. 2010;612:353-364
Analysis of the KIR repertoire in human NK cells by flow cytometry.
Björkström NK; Fauriat C; Bryceson YT; Sandberg JK; Ljunggren H-G; Malmberg K-J
Article: HEALTH INFORMATICS JOURNAL. 2009;15(4):305-319
Data extraction from a semi-structured electronic medical record system for outpatients: A model to facilitate the access and use of data for quality control and research
Kristianson KJ; Ljunggren H; Gustafsson LL
Article: JOURNAL OF IMMUNOLOGY. 2009;183(10):6612-6618
Expansion of Functionally Skewed CD56-Negative NK Cells in Chronic Hepatitis C Virus Infection: Correlation with Outcome of Pegylated IFN-α and Ribavirin Treatment
Gonzalez VD; Falconer K; Bjorkstrom NK; Blom KG; Weiland O; Ljunggren H-G; Alaeus A; Sandberg JK
Article: BLOOD. 2009;114(19):4117-4127
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
Wood SM; Meeths M; Chiang SCC; Bechensteen AG; Boelens JJ; Heilmann C; Horiuchi H; Rosthoj S; Rutynowska O; Winiarski J; Stow JL; Nordenskjold M; Henter J-I; Ljunggren H-G; Bryceson YT
Article: JOURNAL OF IMMUNOLOGY. 2009;183(8):4921-4930
Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells
Carlsten M; Norell H; Bryceson YT; Poschke I; Schedvins K; Liunggren H-G; Kiessling R; Malmberg K-J
Article: BLOOD. 2009;114(13):2657-2666
Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors
Bryceson YT; Ljunggren H-G; Long EO
Article: IMMUNOTHERAPY. 2009;1(5):753-764
Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a Phase I clinical study
Barkholt L; Alici E; Conrad R; Sutlu T; Gilljam M; Stellan B; Christensson B; Guven H; Bjorkstrom NK; Soderdahl G; Cederlund K; Kimby E; Aschan J; Ringden O; Ljunggren H-G; Dilber MS
Article: BLOOD. 2009;114(1):95-104
KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression
Andersson S; Fauriat C; Malmberg J-A; Ljunggren H-G; Malmberg K-J
Article: INFECTION AND IMMUNITY. 2009;77(3):970-976
Transmission of Toxoplasma gondii from Infected Dendritic Cells to Natural Killer Cells
Persson CM; Lambert H; Vutova PP; Dellacasa-Lindberg I; Nederby J; Yagita H; Ljunggren H-G; Grandien A; Barragan A; Chambers BJ
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2957-2961
Tumor cell recognition by the NK cell activating receptor NKG2D
Bryceson YT; Ljunggren H-G
Article: JOURNAL OF IMMUNOLOGY. 2008;181(9):6010-6019
Estimation of the Size of the Alloreactive NK Cell Repertoire: Studies in Individuals Homozygous for the Group A KIR Haplotype
Fauriat C; Andersson S; Bjorklund AT; Carlsten M; Schaffer M; Bjorkstrom NK; Baumann BC; Michaelsson J; Ljunggren H-G; Malmberg K-J
Article: JOURNAL OF IMMUNOLOGY. 2008;181(6):4219-4228
Elevated numbers of FcγRIIIA⁺ (CD16⁺) effector CD8 T cells with NK cell-like function in chronic hepatitis C virus infection
Bjorkstrom NK; Gonzalez VD; Malmberg K-J; Falconer K; Alaeus A; Nowak G; Jorns C; Ericzon B-G; Weiland O; Sandberg JK; Ljunggren H-G
Article: JOURNAL OF IMMUNOLOGY. 2008;181(5):3057-3066
Cannabinoids affect dendritic cell (DC) potassium channel function and modulate DC T cell stimulatory capacity
Wacnik PW; Luhr KM; Hill RH; Ljunggren H-G; Kristensson K; Svensson M
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):113
Göran Möller 1936-2008.
Jonsson R; Ljunggren H-G; Natvig JB; Orn A
Article: BLOOD. 2008;111(6):3155-3162
Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components
Alici E; Sutlu T; Boejrkstrand B; Gilljam M; Stellan B; Nahi H; Quezada HC; Gahrton G; Ljunggren H-G; Dilber MS
Article: JOURNAL OF MEDICAL GENETICS. 2008;45(3):134-141
Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis
Rudd E; Bryceson YT; Zheng C; Edner J; Wood SM; Ramme K; Gavhed S; Gurgey A; Hellebostad M; Bechensteen AG; Ljunggren H-G; Fadeel B; Nordenskjold M; Henter J-I
Article: CELLULAR MICROBIOLOGY. 2008;10(2):426-436
IFN-γ production dominates the early human natural killer cell response to Coxsackievirus infection
Huhn MH; Hultcrantz M; Lind K; Ljunggren H-G; Malmberg K-J; Flodstrom-Tullberg M
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2008;330(1-2):64-74
Application of nine-color flow cytometry for detailed studies of the phenotypic complexity and functional heterogeneity of human lymphocyte subsets
Gonzalez VD; Bjorkstroem NK; Malmberg K-J; Moll M; Kuylenstierna C; Michalsson J; Ljunggren H-G; Sandberg JK
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2008;83(1):56-63
Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells
Wagner CS; Walther-Jallow L; Buentke E; Ljunggren H-G; Achour A; Chambers BJ
Article: EXPERIMENTAL HEMATOLOGY. 2007;35(12):1839-1846
Anti-myeloma activity of endogenous and adoptively transferred activated natural killer cells in experimental multiple myeloma model
Alici E; Konstantinidis KV; Sutlu T; Aints A; Gahrton G; Ljunggren H-G; Dilber MS
Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;373(3):695-705
Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1
Wagner CS; Roelle A; Cosman D; Ljunggren H-G; Berndt KD; Achour A
Article: CANCER RESEARCH. 2007;67(18):8450-8455
Induction of protective CTL immunity against peptide transporter TAP-deficient tumors through dendritic cell vaccination
Chambers B; Grufman P; Fredriksson V; Andersson K; Roseboom M; Laban S; Camps M; Wolpert EZ; Wiertz EJHJ; Offringa R; Ljunggren H-G; van Hall T
Article: BLOOD. 2007;110(6):1906-1915
Defective cytotoxic lymphocyte degranulation in syntaxin-11-deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
Bryceson YT; Rudd E; Zheng C; Edner J; Ma D; Wood SM; Bechensteen AG; Boelens JJ; Celkan T; Farah RA; Hultenby K; Winiarski J; Roche PA; Nordenskjold M; Henter J-I; Long EO; Ljunggren H-G
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2007;66(2‐3):105
EDITORIAL
Jonsson R; Ljunggren H; Rizzo LV
Article: JOURNAL OF NEUROIMMUNOLOGY. 2007;186(1-2):19-26
Aggravation of experimental autoimmune neuritis in TNF-α receptor 1 deficient mice
Lu M-O; Duan R-S; Quezada HC; Chen Z-G; Mix E; Jin T; Yang X; Ljunggren H-G; Zhu J
Article: JOURNAL OF IMMUNOLOGY. 2007;178(8):5018-5027
Severe defect in thymic development in an insertional mutant mouse model
Assarsson E; Chambers BJ; Hogstrand K; Berntman E; Lundmark C; Fedorova L; Imreh S; Grandien A; Cardell S; Rozell B; Ljunggren H-G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2007;65(4):353-361
NK cell-mediated destruction of influenza A virus-infected peripheral but not central neurones
Backstrom E; Ljunggren H-G; Kristensson K
Article: CANCER RESEARCH. 2007;67(3):1317-1325
DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells
Carlsten M; Bjorkstrom NK; Norell H; Bryceson Y; van Hall T; Baumann BC; Hanson M; Schedvins K; Kiessling R; Ljunggren H-G; Malmberg KJ
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2006;80(6):1345-1353
Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms
Joshi PS; Liu J-Q; Wang Y; Chang X; Richards J; Assarsson E; Shi F-D; Ljunggren H-G; Bai X-F
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;64(3):171
Dear readers of Scandinavian Journal of Immunology and ECI2006 attendees
Jonsson R; Ljunggren H
Article: LEUKEMIA. 2006;20(5):833-839
Evaluation of ex vivo expanded human NK cells on antileukemia activity in SCID-beige mice
Guimaraes F; Guven H; Donati D; Christensson B; Ljunggren HG; Bejarano MT; Dilber MS
Article: FASEB JOURNAL. 2006;20(7):896-905
The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system
Huang D; Shi F-D; Jung S; Pien GC; Wang J; Salazar-Mather TP; He TT; Weaver JT; Ljunggren H-G; Biron CA; Littman DR; Ransohoff RM
Article: NATURE MEDICINE. 2006;12(4):417-424
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants
van Hall T; Wolpert EZ; van Veelen P; Laban S; van der Veer M; Roseboom M; Bres S; Grufman P; de Ru A; Meiring H; de Jong A; Franken K; Teixeira A; Valentijn R; Drijfhout JW; Koning F; Camps M; Ossendorp F; Kärre K; Ljunggren HG; Melief CJM; Offringa R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(13):8950-8957
Dissection of the interaction of the human cytomegalovirus-derived US2 protein with major histocompatibility complex class I molecules - Prominent role of a single arginine residue in human leukocyte antigen-A2
Thilo C; Berglund P; Applequist SE; Yewdell JW; Ljunggren HG; Achour A
Article: JOURNAL OF MOLECULAR BIOLOGY. 2006;356(2):382-396
Structural basis of the differential stability and receptor specificity of H-2D^b in complex with murine versus human β₂-microglobulin
Achour A; Michaëlsson T; Harris RA; Ljunggren HG; Kärre M; Schneider G; Sandalova T
Article: BLOOD. 2006;107(1):159-166
Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
Bryceson YT; March ME; Ljunggren HG; Long EO
Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2005;61(Pt 12):1090-1093
Expression, refolding and crystallization of murine MHC class IH-2D^b in complex with human β₂-microglobulin
Sandalova T; Michaëlsson J; Harris RA; Ljunggren HG; Kärre K; Schneider G; Achour A
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(11):1320-1328
Efficient gene transfer into primary human natural killer cells by retroviral transduction
Guven H; Konstantinidis KV; Alici E; Aints A; Abedi-Valugerdi M; Christensson B; Ljunggren HG; Dilber MS
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2005;62(5):437-444
Blockade of CTLA-4 promotes airway inflammation in naive mice exposed to aerosolized allergen but fails to prevent inhalation tolerance
Alenmyr L; Matheu V; Uller L; Greiff L; Malm-Erjefält M; Ljunggren HG; Persson CGA; Korsgren M
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2005;202(7):1001-1012
Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells
Bryceson YT; March ME; Barber DF; Ljunggren HG; Long EO
Article: JOURNAL OF IMMUNOLOGY. 2005;175(6):3882-3891
Activation of innate immunity, inflammation, and potentiation of DNA vaccination through mammalian expression of the TLR5 agonist flagellin
Applequist SE; Rollman E; Wareing MA; Lidén M; Rozell B; Hinkula J; Ljunggren HG
Article: JOURNAL OF NEUROVIROLOGY. 2005;11(4):395-402
Effects on synaptic activity in cultured hippocampal neurons by influenza A viral proteins
Brask J; Chauhan A; Hill RH; Ljunggren HG; Kristensson K
Article: TRENDS IN IMMUNOLOGY. 2005;26(7):347-349
Development and function of CD1d-restricted NKT cells: influence of sphingolipids, SAP and sex
Sandberg JK; Ljunggren HG
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(2):159-164
Targeting IL-2 to the endoplasmic reticulum confines autocrine growth stimulation to NK-92 cells
Konstantinidis KV; Alici E; Aints A; Christensson B; Ljunggren HG; Dilber MS
Article: NEUROBIOLOGY OF DISEASE. 2004;17(2):171-178
IL-12p35 deficiency alleviates kainic acid-induced hippocampal neurodegeneration in C57BL/6 mice
Chen ZG; Duan RS; Q HC; Wu QY; Mix E; Winblad B; Ljunggren HG; Zhu J
Article: TRANSPLANTATION. 2004;78(7):1081-1085
Increased infection-related mortality in KIR-ligand-mismatched unrelated allogeneic hematopoietic stem-cell transplantation
Schaffer M; Malmberg KJ; Ringdén O; Ljunggren HG; Remberger M
Article: SCIENCE. 2004;305(5687):1153-1157
Enhanced dendritic cell antigen capture via toll-like receptor-induced actin remodeling
West MA; Wallin RPA; Matthews SP; Svensson HG; Zaru R; Ljunggren HG; Prescott AR; Watts C
Article: JOURNAL OF IMMUNOLOGY. 2004;173(1):174-180
NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions
Assarsson E; Kambayashi T; Schatzle JD; Cramer SO; von Bonin A; Jensen PE; Ljunggren HG; Chambers BJ
Article: JOURNAL OF IMMUNOLOGY. 2004;172(9):5504-5511
Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition
Velloso LM; Michaëlsson J; Ljunggren HG; Schneider G; Achour A
Article: JOURNAL OF VIROLOGY. 2004;78(9):4776-4782
Scrapie protein degradation by cysteine proteases in CD11c⁺ dendritic cells and GT1-1 neuronal cells
Luhr KM; Nordström EK; Löw P; Ljunggren HG; Taraboulos A; Kristensson K
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(14):4972-4977
Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition
Lind MH; Rozell B; Wallin RPA; van Hogerlinden M; Ljunggren HG; Toftgård R; Sur I
Journal article: ATHEROSCLEROSIS PLUS. 2004;5(1):42
W07.183 CD1d-dependent activation of NKT cells aggravates atherosclerosis
Tupin E; Nicoletti A; Elhage R; Rudling M; Ljunggren H; Hansson G; Berne GP
Article: BRAIN BEHAVIOR AND IMMUNITY. 2004;18(2):175-185
Kainic acid-induced excitotoxic hippocampal neurodegeneration in C57BL/6 mice: B cell and T cell subsets may contribute differently to the pathogenesis
Chen ZG; Yu S; Concha HQ; Zhu Y; Mix E; Winblad B; Ljunggren HG; Zhu J
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2004;199(3):417-422
CD1d-dependent activation of NKT cells aggravates atherosclerosis
Tupin E; Nicoletti A; Elhage R; Rudling M; Ljunggren HG; Hansson GK; Berne GP
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2004;63(2):120-128
Increased susceptibility to experimental autoimmune neuritis after upregulation of the autoreactive T cell response to peripheral myelin antigen in apolipoprotein E-deficient mice
Yu S; Duan RS; Chen ZG; Quezada HC; Bao L; Nennesmo I; Zhu SW; Winblad B; Ljunggren HG; Zhu J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2004;146(1-2):33-38
Reduced susceptibility to kainic acid-induced excitoxicity in T-cell deficient CD4/CD8(-/-) and middle-aged C57BL/6 mice
Chen ZG; Ljunggren HG; Zhu SW; Winblad B; Zhu J
Article: JOURNAL OF IMMUNOLOGY. 2004;172(1):123-129
NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy
Hayakawa Y; Screpanti V; Yagita H; Grandien A; Ljunggren HG; Smyth MJ; Chambers BJ
Article: LEUKEMIA. 2003;17(10):1973-1980
Expansion of natural killer (NK) and natural killer-like T (NKT)-cell populations derived from patients with B-chronic lymphocytic leukemia (B-CLL): a potential source for cellular immunotherapy
Guven H; Gilljam M; Chambers BJ; Ljunggren HG; Christensson B; Kimby E; Dilber MS
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(10):2727-2735
Regulation of perforin-independent NK cell-mediated cytotoxicity
Wallin RPA; Screpanti V; Michaëlsson J; Grandien A; Ljunggren HG
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(39):37730-37735
The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family
Kaiser L; Grönlund H; Sandalova T; Ljunggren HG; van Hage-Hamsten M; Achour A; Schneider G
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2003;132(1):25-26
Three-dimensional structure of Fel d 1, the major allergen in cat
Kaiser L; Grönlund H; Sandalova T; Ljunggren HG; Achour A; Schneider G; van Hage-Hamsten M
Article: IMMUNOLOGY. 2003;109(3):384-391
Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein
Westerberg L; Wallin RPA; Greicius G; Hans-Gustaf L; Severinson E
Article: CARDIOVASCULAR RESEARCH. 2003;59(1):234-240
Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice
Elhage R; Jawien J; Rudling M; Ljunggren HG; Takeda K; Akira S; Bayard F; Hansson GK
Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 2003;59(Pt 6):1103-1105
Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d I
Kaiser L; Grönlund H; Sandalova T; Ljunggren HG; Schneider G; van Hage-Hamsten M; Achour A
Article: JOURNAL OF IMMUNOLOGY. 2003;170(5):2399-2408
Memory CD8⁺ T cells provide an early source of IFN-γ
Kambayashi T; Assarsson E; Lukacher AE; Ljunggren HG; Jensen PE
Article: NEUROBIOLOGY OF DISEASE. 2003;12(1):73-81
Exogenous soluble tumor necrosis factor receptor type I ameliorates murine experimental autoimmune neuritis
Bao L; Lindgren JU; Zhu Y; Ljunggren HG; Zhu J
Article: VIRAL IMMUNOLOGY. 2003;16(3):415-423
Invasion and persistence of the neuroadapted influenza virus A/WSN/33 in the mouse olfactory system
Aronsson F; Robertson B; Ljunggren HG; Kristensson K
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2003;33(1):92-100
Natural killer cell-mediated lysis of dorsal root ganglia neurons via RAE1/NKG2D interactions
Backström E; Chambers BJ; Ho EL; Naidenko OV; Mariotti R; Fremont DH; Yokoyama WM; Kristensson K; Ljunggren HG
Article: JOURNAL OF VIROLOGY. 2002;76(23):12259-12264
Processing and degradation of exogenous prion protein by CD11c⁺ myeloid dendritic cells in vitro
Luhr KM; Wallin RPA; Ljunggren HG; Löw P; Taraboulos A; Kristensson K
Article: BRAIN PATHOLOGY. 2002;12(4):420-429
The critical role of IL-12p40 in initiating, enhancing, and perpetuating pathogenic events in murine experimental autoimmune neuritis
Bao L; Lindgren JU; van der Meide P; Zhu SW; Ljunggren HG; Zhu J
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2002;119(4):850-857
Natural killer and dendritic cell contact in lesional atopic dermatitis skin -: Malassezia-influenced cell interaction
Buentke E; Heffler LC; Wilson JL; Wallin RPA; Löfman C; Chambers BJ; Ljunggren HG; Scheynius A
Article: EXPERIMENTAL NEUROLOGY. 2002;177(1):314-320
CD4 and CD8 T cells, but not B cells, are critical to the control of murine experimental autoimmune neuritis
Zhu Y; Bao L; Zhu SW; Chen ZG; van der Meide P; Nennesmo I; Winblad B; Ljunggren HG; Zhu J
Article: INTERNATIONAL IMMUNOLOGY. 2002;14(9):1065-1074
Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines
Applequist SE; Wallin RPA; Ljunggren HG
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2002;61(7):614-622
Neutralizing antibodies to IL-18 ameliorate experimental autoimmune neuritis by counter-regulation of autoreactive Th1 responses to peripheral myelin antigen
Yu S; Chen ZG; Mix E; Zhu SW; Winblad B; Ljunggren HG; Zhu J
Article: BRAIN RESEARCH. 2002;931(2):135-145
Excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57BL/6 mice
Chen ZG; Ljunggren HG; Bogdanovic N; Nennesmo I; Winblad B; Zhu J
Article: JOURNAL OF NEUROVIROLOGY. 2002;8(SUPPL 1):30-31
Viral infections & autoimmune disease
Backstrom E; Chambers B; Kristensson K; Ljunggren H-G
Article: CELL TRANSPLANTATION. 2002;11(7):715-720
Co-stimulatory molecules in islet xenotransplantation: CTLA4Ig treatment in CD40 ligand-deficient mice
Benda B; Ljunggren HG; Peach R; Sandberg JO; Korsgren O
Article: JOURNAL OF IMMUNOLOGY. 2001;167(12):6706-6710
Cutting edge:: Regulation of CD8⁺ T cell proliferation by 2B4/CD48 interactions
Kambayashi T; Assarsson E; Chambers BJ; Ljunggren HG
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2001;70(6):903-910
cAMP-elevating agents suppress dendritic cell function
Kambayashi T; Wallin RPA; Ljunggren HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(11):3248-3254
IL-2 down-regulates the expression of TCR and TCR-associated surface molecules on CD8⁺ T cells
Kambayashi T; Assarsson E; Chambers BJ; Ljunggren HG
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2001;31(10):1583-1593
The allergenic yeast Malassezia furfur induces maturation of human dendritic cells
Buentke E; Heffler LC; Wallin RPA; Löfman C; Ljunggren HG; Scheynius A
Article: HUMAN IMMUNOLOGY. 2001;62(10):1092-1098
A new method for in vitro expansion of cytotoxic human CD3^-CD56⁺ natural killer cells
Carlens S; Gilljam M; Chambers BJ; Aschan J; Guven H; Ljunggren HG; Christensson B; Dilber MS
Article: JOURNAL OF IMMUNOLOGY. 2001;167(5):3000-3006
Control of the autoimmune response by type 2 nitric oxide synthase
Shi FD; Flodström M; Kim SH; Pakala S; Cleary M; Ljunggren HG; Sarvetnick N
Article: INFECTION AND IMMUNITY. 2001;69(9):5726-5735
In vivo activation of dendritic cells and T cells during Salmonella enterica serovar typhimurium infection
Yrlid U; Svensson M; Håkansson A; Chambers BJ; Ljunggren HG; Wick MJ
Article: JOURNAL OF IMMUNOLOGY. 2001;167(4):2068-2073
A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells
Screpanti V; Wallin RPA; Ljunggren HG; Grandien A
Article: EXPERIMENTAL NEUROLOGY. 2001;169(2):472-478
Suppression of autoimmune neuritis in IFN-γ receptor-deficient mice
Zhu Y; Ljunggren HG; Mix E; Li HL; van der Meide P; Elhassan AM; Winblad B; Zhu J
Article: JOURNAL OF IMMUNOLOGY. 2001;166(10):6430-6436
Anti-CTLA-4 antibody treatment triggers determinant spreading and enhances murine myasthenia gravis
Wang HB; Shi FD; Li HL; Chambers BJ; Link H; Ljunggren HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(5):1523-1530
Expression of the DX5 antigen on CD8⁺ T cells is associated with activation and subsequent cell death or memory during influenza virus infection
Kambayashi T; Assarsson E; Chambers BJ; Ljunggren HG
Article: JOURNAL OF NEUROIMMUNOLOGY. 2001;115(1-2):111-117
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade enhances incidence and severity of experimental autoimmune neuritis in resistant mice
Zhu J; Zou LP; Zhu SW; Mix E; Shi FD; Wang HB; Volkmann I; Winblad B; Schalling M; Ljunggren HG
Article: JOURNAL OF NEUROVIROLOGY. 2001;7(2):117-124
Persistence of the influenza A/WSN/33 virus RNA at midbrain levels of immunodefective mice
Aronsson F; Karlsson H; Ljunggren HG; Kristensson K
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(3):869-875
Purified MHC class I molecules inhibit activated NK cells in a cell-free system in vitro
Kambayashi T; Michaëlsson J; Fahlén L; Chambers BJ; Sentman CL; Kärre K; Ljunggren HG
Article: JOURNAL OF NEUROIMMUNOLOGY. 2001;114(1-2):114-121
CD28-B7 costimulation: a critical role for initiation and development of experimental autoimmune neuritis in C57BL/6 mice
Zhu Y; Ljunggren HG; Mix E; Li HL; van der Meide P; Elhassan AM; Winblad B; Zhu J
Article: INTERNATIONAL JOURNAL OF CANCER. 2001;91(3):373-378
Soluble MHC class I molecules induce cellular death in a CD8⁺ T-cell hybridoma tumor model
Kambayashi T; Ichihara F; Jensen PE; Ljunggren HG
Article: INTERNATIONAL IMMUNOLOGY. 2001;13(1):23-29
Assembly of tapasin-associated MHC class I in the absence of the transporter associated with antigen processing (TAP)
Paulsson KM; Anderson PO; Chen SW; Sjögren HO; Ljunggren HG; Wang P; Li SL
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(1):225-232
Disruption of the IL-1β gene diminishes acetylcholine receptor-induced immune responses in a murine model of myasthenia gravis
Huang DR; Shi FD; Giscombe R; Zhou YH; Ljunggren HG; Lefvert AK
Article: MOLECULAR CANCER RESEARCH. 2001;12(1):51-60
Differentiation of Ly49s-positive or -negative natural killer cells is inhibited by anti-H-2^b monoclonal antibodies acting at the level of bone marrow progenitors from B6 mice
Delfino DV; Salcedo M; Di Marco B; Ayroldi E; Nocentini G; Bruscoli S; Brunetti L; Ljunggren HG; Riccardi C
Article: NATURE MEDICINE. 2000;6(12):1348-1354
Efficient presentation of exogenous antigen by liver endothelial cells to CD8⁺ T cells results in antigen-specific T-cell tolerance
Limmer A; Ohl J; Kurts C; Ljunggren HG; Reiss Y; Groettrup M; Momburg F; Arnold B; Knolle PA
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2000;62(5):717-721
P0 protein peptide 180-199 together with pertussis toxin induces experimental autoimmune neuritis in resistant C57BL/6 mice
Zou LP; Ljunggren HG; Levi M; Nennesmo I; Wahren B; Mix E; Winblad B; Schalling M; Zhu J
Article: JOURNAL OF IMMUNOLOGY. 2000;165(9):4964-4969
Emergence of CD8⁺ T cells expressing NK cell receptors in influenza A virus-infected mice
Kambayashi T; Assarsson E; Michaëlsson J; Berglund P; Diehl AP; Chambers BJ; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 2000;165(9):4895-4900
Direct NK cell-mediated lysis of syngenic dorsal root ganglia neurons in vitro
Backström E; Chambers BJ; Kristensson K; Ljunggren HG
Journal article: BLOOD. 2000;96(7):2568-2573
Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10
Cervenak L; Morbidelli L; Donati D; Donnini S; Kambayashi T; Wilson JL; Axelson H; Castaños-Velez E; Ljunggren H-G; De Waal Malefyt R; Granger HJ; Ziche M; Bejarano MT
Article: BLOOD. 2000;96(7):2568-2573
Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10
Cervenak L; Morbidelli L; Donati D; Donnini S; Kambayashi T; Wilson JL; Axelson H; Castaños-Velez E; Ljunggren HG; Malefyt RD; Granger HJ; Ziche M; Bejarano MT
Article: JOURNAL OF IMMUNOLOGY. 2000;165(7):3673-3679
CD8⁺ T cells rapidly acquire NK1.1 and NK cell-associated molecules upon stimulation in vitro and in vivo
Assarsson E; Kambayashi T; Sandberg JK; Hong S; Taniguchi M; Van Kaer L; Ljunggren HG; Chambers BJ
Article: INTERNATIONAL IMMUNOLOGY. 2000;12(10):1381-1388
Tumor necrosis factor receptor-1 is critically involved in the development of experimental autoimmune myasthenia gravis
Wang HB; Li H; Shi FD; Chambers BJ; Link H; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 2000;165(6):3099-3104
IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-γ by NK cells
Shi FD; Takeda K; Akira S; Sarvetnick N; Ljunggren HG
Article: NATURE IMMUNOLOGY. 2000;1(3):245-251
Natural killer cells determine the out-come of B cell-mediated autoimmunity
Shi FD; Wang HB; Li HL; Hong S; Taniguchi M; Link H; Van Kaer L; Ljunggren HG
Article: NATURE IMMUNOLOGY. 2000;1(3):234-238
Impaired immune responses and altered peptide repertoire in tapasin-deficient mice
Garbi N; Tan P; Diehl AD; Chambers BJ; Ljunggren HG; Momburg F; Hämmerling GJ
Article: CLINICAL IMMUNOLOGY. 2000;95(2):156-162
Role for interferon-γ in rat strains with different susceptibility to experimental autoimmune myasthenia gravis
Wang HB; Shi FD; Li HL; van der Meide PH; Ljunggren HG; Link H
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(4):1094-1101
Role of Qa-1^b-binding receptors in the specificity of developing NK cells
Salcedo M; Colucci F; Dyson PJ; Cotterill LA; Lemonnier FA; Kourilsky P; Di Santo JP; Ljunggren HG; Abastado JP
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51(3):219-223
β₂-microglobulin/CD8-/- mice reveal significant role for CD8⁺ T cells in graft rejection responses in β₂-microglobulin -/- mice
Freland S; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1999;163(12):6365-6370
Targeting of human dendritic cells by autologous NK cells
Wilson JL; Heffler LC; Charo J; Scheynius A; Bejarano MT; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1999;163(8):4207-4212
NK cell triggering by the human costimulatory molecules CD80 and CD86
Wilson JL; Charo J; Martín-Fontecha A; Dellabona P; Casorati G; Chambers BJ; Kiessling R; Bejarano MT; Ljunggren HG
Article: JOURNAL OF NEUROVIROLOGY. 1999;5(4):355-362
Selective targeting of habenular, thalamic midline and monoaminergic brainstem neurons by neurotropic influenza A virus in mice
Mori I; Diehl AD; Chauhan A; Ljunggren HG; Kristensson K
Article: JOURNAL OF IMMUNOLOGY. 1999;162(10):5910-5916
Triggering of murine NK cells by CD40 and CD86 (B7-2)
Martín-Fontecha A; Assarsson E; Carbone E; Kärre K; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1999;162(10):5757-5763
Mechanisms of nasal tolerance induction in experimental autoimmune myasthenia gravis: Identification of regulatory cells
Shi FD; Li HL; Wang HB; Bai XF; van der Meide PH; Link H; Ljunggren HG
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1999;189(3):553-562
Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice
Korsgren M; Persson CGA; Sundler F; Bjerke T; Hansson T; Chambers BJ; Hong SM; Van Kaer L; Ljunggren HG; Korsgren O
Article: JOURNAL OF NEUROIMMUNOLOGY. 1999;94(1-2):196-203
Induction of experimental autoimmune neuritis in CD4^-8^- C57BL/6J mice
Zhu J; Nennesmo I; Deng GM; Levi M; Wahren B; Diab A; Mix E; Zhou JN; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1998;161(12):6475-6479
MHC class I mosaic mice reveal insights into control of Ly49C inhibitory receptor expression in NK cells
Andersson M; Freland S; Johansson MH; Wallin R; Sandberg JK; Chambers BJ; Christensson B; Lendahl U; Lemieux S; Salcedo M; Ljunggren HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(12):4356-4361
The Qa-1^b molecule binds to a large subpopulation of murine NK cells
Salcedo M; Bousso P; Ljunggren HG; Kourilsky P; Abastado JP
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(11):3587-3593
Differential requirements for CD28 and CD40 ligand in the induction of experimental autoimmune myasthenia gravis
Shi FD; He B; Li HL; Matusevicius D; Link H; Ljunggren HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(4):1315-1321
Fine tuning of natural killer cell specificity and maintenance of self tolerance in MHC class I-deficient mice
Salcedo M; Andersson M; Lemieux S; Van Kaer L; Chambers BJ; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1998;160(2):572-579
Rejection of allogeneic and syngeneic but not MHC class I-deficient tumor grafts by MHC class I-deficient mice
Freland S; Chambers BJ; Andersson M; Van Kaer L; Ljunggren HG
Article: JOURNAL OF IMMUNOLOGY. 1997;159(11):5364-5371
TAP peptide transporter-independent presentation of heat-killed Sendai virus antigen on MHC class I molecules by splenic antigen-presenting cells
Liu TM; Chambers B; Diehl AD; Van Kaer L; Jondal M; Ljunggren HG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1997;94(21):11496-11501
Generation of CD8(+) T cells specific for transporter associated with antigen processing deficient cells
Wolpert EZ; Petersson M; Chambers BJ; Sandberg JK; Kiessling R; Ljunggren HG; Karre K
Article: JOURNAL OF IMMUNOLOGY. 1997;159(7):3195-3202
Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10
SalazarOnfray F; Charo J; Petersson M; Freland S; Noffz G; Qin ZH; Blankenstein T; Ljunggren HG; Kiessling R
Article: JOURNAL OF IMMUNOLOGY. 1997;159(7):3189-3194
NK cell receptor calibration - Effects of MHC class I induction on killing by Ly49A(high) and Ly49A(low) NK cells
OlssonAlheim MY; Salcedo M; Ljunggren HG; Karre K; Sentman CL
Article: JOURNAL OF MEDICAL VIROLOGY. 1997;52(4):362-369
Spread of measles virus through axonal pathways into limbic structures in the brain of TAP1 -/- mice
Urbanska EM; Chambers BJ; Ljunggren HG; Norrby E; Kristensson K
Journal article: CLINICAL NEUROLOGY AND NEUROSURGERY. 1997;99:s29
O-9-129 Natural resistance against tumors grafted into the brain in association with histocompatibility-class-I-antigen expression
Yamasaki T; Akiyamna Y; Fukuda M; Kimura Y; Uemura T; Moritake K; Ljunggren HG; Karre K; Klein G
Journal article: IMMUNOLOGY LETTERS. 1997;56:386
The role of natural killer (NK) cells in regulating antigen presenting cells
Chambers BJ; Wilson JL; Salcedo MS; Ljunggren HG
Journal article: IMMUNOLOGY LETTERS. 1997;56:243
Constitutive macropinocytosis allows TAP-dependent class I MHC presentation of exogenous soluble antigen by bone-marrow derived dendritic cells
Norbury CC; Chambers BJ; Prescott AR; Ljunggren HG; Watts C
Journal article: IMMUNOLOGY LETTERS. 1997;56:385
Altered expression of Ly49 inhibitory receptors on NK cells from MHC class I deficient mice
Salcedo M; Diehl AD; Olsson-Alheim MY; Sundbäck J; Van Kaer L; Kärre K; Ljunggren HG
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1997;45(5):527-533
MHC class I presentation of live and heat-inactivated Sendai virus antigen in T2K(b) cells depends on an intracellular compartment with endosomal characteristics
Liu T; Zhou X; AbdelMotal UM; Ljunggren HG; Jondal M
Article: JOURNAL OF IMMUNOLOGY. 1997;158(7):3174-3180
Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice
Salcedo M; Diehl AD; OlssonAlheim MY; Sundback J; VanKaer L; Karre K; Ljunggren HG
Article: TRANSPLANTATION. 1997;63(1):119-123
Major histocompatibility complex class I-independent killing of xenogenic targets by rat allospecific natural killer cells
Torgersen KM; Salcedo M; Vaage JT; Naper C; Rolstad B; Ljunggren HG; Hoglund P
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(1):280-288
Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells
Norbury CC; Chambers BJ; Prescott AR; Ljunggren HG; Watts C
Article: IMMUNOLOGY LETTERS. 1996;54(1):31-35
External glycopeptide binding to MHC class-I in relation to expression of TAP transporters, beta 2-microglobulin and to pH
AbdelMotal UM; Dahmen J; Liu TM; Ljunggren HG; Jondal M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(40):24830-24835
Binding of H-2K(b)-specific peptides to TAP and major histocompatibility complex class I in microsomes from wild-type, TAP1, and beta(2)-microglobulin mutant mice
Wang P; Raynoschek C; Svensson K; Ljunggren HG
Article: IMMUNITY. 1996;5(4):311-317
Triggering of natural killer cells by the costimulatory molecule CD80 (B7-1)
Chambers BJ; Salcedo M; Ljunggren HG
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1996;26(8):1844-1850
Chemically induced sarcomas from nude mice are more immunogenic than similar sarcomas from congenic normal mice
Svane IM; Engel AM; Nielsen MB; Ljunggren HG; Rygaard J; Werdelin O
Article: INTERNATIONAL JOURNAL OF CANCER. 1996;67(3):365-371
Natural resistance against tumors grafted into the brain in association with histocompatibility-class-I-antigen expression
Yamasaki T; Akiyama Y; Fukuda M; Kimura Y; Moritake K; Kikuchi H; Ljunggren HG; Karre K; Klein G
Article: TRANSPLANTATION. 1996;61(9):1313-1320
Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice
KarlssonParra A; Ridderstad A; Wallgren AC; Moller E; Ljunggren HG; Korsgren O
Journal article: HUMAN IMMUNOLOGY. 1996;47(1-2):110
P599 Reactivity and specificity of CD8+ T cells in MHC class I deficient mice
Ljunggren H-G; Chambers B; Freland S; Glas R; Sandberg J; Kärre K; Tonegawa S; Ploegh HL; Van Kaer L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1996;26(2):288-293
TAP1-deficient mice select a CD8(+) T cell repertoire that displays both diversity and peptide specificity
Sandberg JK; Chambers BJ; VanKaer L; Karre K; Ljunggren HG
Article: TRANSPLANTATION. 1995;60(3):281-286
NATURAL-KILLER-CELL INTERACTION WITH MURINE ALLOGENEIC MHC CLASS-I MOLECULES
SALCEDO M; HOGLUND P; LJUNGGREN HG
Article: MOLECULAR IMMUNOLOGY. 1995;32(11):789-794
ALTERED MHC CLASS-I PRESENTED PEPTIDE REPERTOIRE IS NOT SUFFICIENT TO INDUCE NK CELL-MEDIATED F-1-HYBRID RESISTANCE
SALCEDO M; HOGLUND P; ACHOUR A; THORPE CJ; LJUNGGREN HG
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):66-75
CHARACTERIZATION OF TAP-INDEPENDENT AND BREFELDIN A-RESISTANT PRESENTATION OF SENDAI VIRUS-ANTIGEN TO CD8(+) CYTOTOXIC T-LYMPHOCYTES
ZHOU X; LIU T; FRANKSSON L; LEDERER E; LJUNGGREN HG; JONDAL M
Article: INTERNATIONAL IMMUNOLOGY. 1995;7(6):975-984
MHC class I expression and CD8+ T cell development in TAP1/beta 2-microglobulin double mutant mice.
Ljunggren HG; Van Kaer L; Sabatine MS; Auchincloss H; Tonegawa S; Ploegh HL
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(5):1286-1291
INHIBITION OF NATURAL-KILLER CELL-MEDIATED BONE-MARROW GRAFT-REJECTION BY ALLOGENEIC MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I, BUT NOT CLASS-II MOLECULES
OHLEN C; HOGLUND P; SENTMAN CL; CARBONE E; LJUNGGREN HG; KOLLER B; KARRE K
Article: CANCER RESEARCH. 1995;55(9):1911-1916
REJECTION OF TUMORS IN MICE WITH SEVERE COMBINED IMMUNODEFICIENCY SYNDROME DETERMINED BY THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I EXPRESSION ON THE GRAFT
GLAS R; WALDENSTROM M; HOGLUND P; KLEIN G; KARRE K; LJUNGGREN HG
Article: JOURNAL OF IMMUNOLOGY. 1995;154(7):3147-3155
HEAT-INACTIVATED SENDAI-VIRUS CAN ENTER MULTIPLE MHC CLASS-I PROCESSING PATHWAYS AND GENERATE CYTOTOXIC T-LYMPHOCYTE RESPONSES IN-VIVO
LIU TM; ZHOU XZ; ORVELL C; LEDERER E; LJUNGGREN HG; JONDAL M
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 1995;181(3):1111-1122
PEPTIDE INFLUENCES THE FOLDING AND INTRACELLULAR-TRANSPORT OF FREE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I HEAVY-CHAINS
MACHOLD RP; ANDREE S; VANKAER L; LJUNGGREN HG; PLOEGH HL
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(1):174-178
Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice.
Ljunggren HG; Van Kaer L; Ashton-Rickardt PG; Tonegawa S; Ploegh HL
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1994;24(8):1863-1868
PRESENTATION OF VIRAL-ANTIGENS RESTRICTED BY H-2K(B), D-B OR K-D IN PROTEASOME SUBUNIT LMP2-DEFICIENT AND LMP7-DEFICIENT CELLS
ZHOU XZ; MOMBURG F; LIU TM; MOTAL UMA; JONDAL M; HAMMERLING GJ; LJUNGGREN HG
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994;91(14):6520-6524
ALTERED NATURAL-KILLER-CELL REPERTOIRE IN TAP-1 MUTANT MICE
LJUNGGREN HG; VANKAER L; PLOEGH HL; TONEGAWA S
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994;91(14):6525-6528
POSITIVE SELECTION OF SELFREACTIVE AND ALLOREACTIVE CD8+ T-CELLS IN TAP-1 MUTANT MICE
ALDRICH CJ; LJUNGGREN HG; VANKAER L; ASHTONRICKARDT PG; TONEGAWA S; FORMAN J
Journal article: INTERNATIONAL IMMUNOLOGY. 1994;6(7):1061-1070
PERIPHERAL LYMPHOID DEVELOPMENT AND FUNCTION IN TCR MUTANT MICE
MOMBAERTS P; MIZOGUCHI E; LJUNGGREN HG; IACOMINI J; ISHIKAWA H; WANG L; GRUSBY MJ; GLIMCHER LH; WINN HJ; BHAN AK; TONEGAWA S
Journal article: JOURNAL OF IMMUNOLOGY. 1994;152(4):1702-1708
RESISTANCE TO NATURAL-KILLER-CELL LYSIS CONFERRED BY TAP1/2 GENES IN HUMAN ANTIGEN-PROCESSING MUTANT-CELLS
SALCEDO M; MOMBURG F; HAMMERLING GJ; LJUNGGREN HG
Journal article: VIROLOGY. 1994;198(2):714-716
T-CELL SUBSETS INVOLVED IN IMMUNITY AGAINST POLYOMA VIRUS-INDUCED TUMORS
LJUNGGREN G; LJUNGGREN HG; DALIANIS T
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1993;23(8):1802-1808
ANTIGEN-PROCESSING MUTANT T2 CELLS PRESENT VIRAL-ANTIGEN RESTRICTED THROUGH H-2KB
ZHOU XZ; GLAS R; LIU TM; LJUNGGREN HG; JONDAL M
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1993;23(8):1796-1801
TAP2-DEFECTIVE RMA-S CELLS PRESENT SENDAI VIRUS-ANTIGEN TO CYTOTOXIC T-LYMPHOCYTES
ZHOU XZ; GLAS R; MOMBURG F; HAMMERLING GJ; JONDAL M; LJUNGGREN HG
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1993;54(6):992-995
IDENTIFICATION OF H-2KB-BINDING, DB-BINDING AND DD-BINDING PEPTIDES DERIVED FROM AMINO-ACID-SEQUENCES OF POLYOMA VIRUS-T ANTIGENS
REINHOLDSSONLJUNGGREN G; FRANKSSON L; DALIANIS T; LJUNGGREN HG
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1993;54(3):518-523
GENERATION AND CONTROL OF METASTASIS IN EXPERIMENTAL TUMOR SYSTEMS - INHIBITION OF EXPERIMENTAL METASTASES BY A TILORONE ANALOG
ALGARRA I; PEREZ M; HOGLUND P; GAFORIO JJ; LJUNGGREN HG; GARRIDO F
Journal article: JOURNAL OF NEUROSURGERY. 1993;78(4):619-629
ROLE OF HISTOCOMPATIBILITY ANTIGEN GENE AND PROTOONCOGENE EXPRESSIONS IN INTRACEREBRAL TUMORIGENICITY OF MOUSE NEUROBLASTOMA
YAMASAKI T; KLEIN G; LJUNGGREN HG; KARRE K; MORITAKE K; PAINE JT; KIKUCHI H
Journal article: EUROPEAN JOURNAL OF CANCER. 1993;29A(2):238-241
MHC CLASS-I EXPRESSION ON PRELYMPHOMATOUS AND LYMPHOMATOUS B-CELLS IS NOT INHIBITED BY AN E-MU-MYC TRANSGENE
ALGARRA I; SILVA S; LJUNGGREN HG
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1992;89(23):11381-11385
MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I-SPECIFIC AND CLASS-I-RESTRICTED KILLING OF BETA(2)-MICROGLOBULIN-DEFICIENT CELLS BY CD8+ CYTOTOXIC LYMPHOCYTES-T
GLAS R; FRANKSSON L; OHLEN C; HOGLUND P; KOLLER B; LJUNGGREN HG; KARRE K
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1992;52(1):153-158
EFFECT OF MHC CLASS-I TRANSFECTION ON LOCAL TUMOR-GROWTH AND METASTASIS IN AN H-2-NEGATIVE CLONE DERIVED FROM A CHEMICALLY-INDUCED FIBROSARCOMA
MIALDEA MJ; MARTIN J; GAFORIO JJ; ALGARRA I; PEREZ M; GONZALEZ A; LJUNGGREN HG; GARRIDO F
Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 1992;175(3):843-846
RESTORATION OF A TUMORIGENIC PHENOTYPE BY BETA-2-MICROGLOBULIN TRANSFECTION TO EL-4 MUTANT-CELLS
GLAS R; STURMHOFEL K; HAMMERLING GJ; KARRE K; LJUNGGREN HG
Journal article: CANCER JOURNAL. 1992;5(6):308-315
ROLE OF BETA-2-MICROGLOBULIN IN CANCER
LJUNGGREN HG
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1991;49(6):906-910
DIFFERENTIAL MESSENGER-RNA LEVELS OF C-MYC, C-FOS AND MHC CLASS-I IN SEVERAL CLONES OF A MURINE FIBROSARCOMA
GAFORIO JJ; PEREZ M; ALGARRA I; MIALDEA MJ; LJUNGGREN HG; GARRIDO F
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1991;88(22):10332-10336
RECOGNITION OF BETA-2-MICROGLOBULIN-NEGATIVE (BETA-2M-) T-CELL BLASTS BY NATURAL-KILLER-CELLS FROM NORMAL BUT NOT FROM BETA-2M- MICE - NONRESPONSIVENESS CONTROLLED BY BETA-2M- BONE-MARROW IN CHIMERIC MICE
HOGLUND P; OHLEN C; CARBONE E; FRANKSSON L; LJUNGGREN HG; LATOUR A; KOLLER B; KARRE K
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1991;21(11):2767-2774
DIFFERENT TYPES OF ALLOSPECIFIC CTL CLONES IDENTIFIED BY THEIR ABILITY TO RECOGNIZE PEPTIDE LOADING-DEFECTIVE TARGET-CELLS
AOSAI F; OHLEN C; LJUNGGREN HG; HOGLUND P; FRANKSSON L; PLOEGH H; TOWNSEND A; KARRE K; STAUSS HJ
Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 1991;174(2):327-334
ALTERATION OF THE NATURAL-KILLER REPERTOIRE IN H-2 TRANSGENIC MICE - SPECIFICITY OF RAPID LYMPHOMA CELL CLEARANCE DETERMINED BY THE H-2 PHENOTYPE OF THE TARGET
HOGLUND P; GLAS R; OHLEN C; LJUNGGREN HG; KARRE K
Journal article: INTERNATIONAL JOURNAL OF CANCER. SUPPLEMENT = JOURNAL INTERNATIONAL DU CANCER. SUPPLEMENT. 1991;6:38-44
THE RMA-S LYMPHOMA MUTANT - CONSEQUENCES OF A PEPTIDE LOADING DEFECT ON IMMUNOLOGICAL RECOGNITION AND GRAFT-REJECTION
LJUNGGREN HG; OHLEN C; HOGLUND P; FRANKSSON L; KARRE K
Journal article: NEUROLOGICAL SURGERY. 1990;18(11):1015-1022
[Experimental analysis of anti-tumor cytotoxic mechanism for hybrid resistance to mouse neuroblastoma].
Yamasaki T; Moritake K; Kikuchi H; Kärre K; Ljunggren HG; Klein G
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1990;46(2):258-261
A WEAKLY TUMORIGENIC PHENOTYPE WITH HIGH MHC CLASS-I EXPRESSION IS ASSOCIATED WITH HIGH METASTATIC POTENTIAL AFTER SURGICAL REMOVAL OF THE PRIMARY MURINE FIBROSARCOMA
PEREZ M; ALGARRA I; LJUNGGREN HG; CABALLERO A; MIALDEA MJ; GAFORIO JJ; KLEIN G; KARRE K; GARRIDO F
Journal article: NATURE. 1990;346(6283):476-480
EMPTY MHC CLASS-I MOLECULES COME OUT IN THE COLD
LJUNGGREN HG; STAM NJ; OHLEN C; NEEFJES JJ; HOGLUND P; HEEMELS MT; BASTIN J; SCHUMACHER TNM; TOWNSEND A; KARRE K; PLOEGH HL
Journal article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1990;20(8):1873-1876
RESTORATION OF H-2B EXPRESSION AND PROCESSING OF ENDOGENOUS ANTIGENS IN THE MHC CLASS-I PATHWAY BY FUSION OF A LYMPHOMA MUTANT TO L-CELLS OF THE H-2K HAPLOTYPE
OHLEN C; BASTIN J; LJUNGGREN HG; IMREH S; KLEIN G; TOWNSEND ARM; KARRE K
Journal article: JOURNAL OF IMMUNOLOGY. 1990;145(1):52-58
RESISTANCE TO H-2-RESTRICTED BUT NOT TO ALLO-H2-SPECIFIC GRAFT AND CYTOTOXIC LYMPHOCYTE-T RESPONSES IN LYMPHOMA MUTANT
OHLEN C; BASTIN J; LJUNGGREN HG; FOSTER L; WOLPERT E; KLEIN G; TOWNSEND ARM; KARRE K
Journal article: TRENDS IN IMMUNOLOGY. 1990;11(7):237-244
IN SEARCH OF THE MISSING SELF - MHC MOLECULES AND NK CELL RECOGNITION
LJUNGGREN HG; KARRE K
Journal article: JOURNAL OF IMMUNOLOGY. 1990;145(1):380-386
TRANSFECTION OF BETA-2-MICROGLOBULIN RESTORES IFN-MEDIATED PROTECTION FROM NATURAL-KILLER-CELL LYSIS IN YAC-1 LYMPHOMA VARIANTS
LJUNGGREN HG; STURMHOFEL K; WOLPERT E; HAMMERLING GJ; KARRE K
Journal article: IMMUNOLOGIC RESEARCH. 1990;9(4):298-313
ROLE OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I MOLECULES IN TUMOR REJECTION - NEW INSIGHTS FROM STUDIES WITH SYNTHETIC PEPTIDES AND TRANSGENIC MICE
HOGLUND P; LJUNGGREN HG; KARRE K; JAY G
Journal article: NEUROLOGIA MEDICO-CHIRURGICA. 1990;30(11 Spec No):800-805
[Cytotoxic effector mechanism and genetic control of non-immunized hybrid resistance to mouse T cell lymphoma transplanted outside and inside the brain].
Yamasaki T; Kikuchi H; Ljunggren HG; Kärre K; Klein G
Journal article: NEUROLOGIA MEDICO-CHIRURGICA. 1990;30(11 Spec No):789-795
[Molecular analysis of relationship between oncogene (N-myc and c-src) expression and major histocompatibility complex antigen gene expression in mouse neuroblastoma lines].
Yamasaki T; Kikuchi H; Yamashita J; Ljunggren HG; Kärre K; Klein G
Journal article: IMMUNOGENETICS. 1990;32(6):440-450
HIGH-RESOLUTION ONE-DIMENSIONAL ISOELECTRIC-FOCUSING OF MOUSE MHC CLASS-I ANTIGENS - IDENTIFICATION OF NATURAL AND EXPERIMENTALLY INDUCED CLASS-I ANTIGENS
LJUNGGREN HG; OUDSHOORNSNOEK M; MASUCCI MG; PLOEGH HL
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1989;44(4):675-680
NK SENSITIVITY AND LUNG CLEARANCE OF MHC-CLASS-I-DEFICIENT CELLS WITHIN A HETEROGENEOUS FIBRO-SARCOMA
ALGARRA I; OHLEN C; PEREZ M; LJUNGGREN HG; KLEIN G; GARRIDO F; KARRE K
Journal article: INTERNATIONAL JOURNAL OF CANCER. 1989;44(4):669-674
EFFECT OF IFN-GAMMA TREATMENT AND INVIVO PASSAGE OF MURINE TUMOR-CELL LINES ON THEIR SENSITIVITY TO LYMPHOKINE-ACTIVATED KILLER (LAK) CELL-LYSIS INVITRO - ASSOCIATION WITH H-2 EXPRESSION ON THE TARGET-CELLS
TSAI L; OHLEN C; LJUNGGREN HG; KARRE K; HANSSON M; KIESSLING R
Journal article: NATURE. 1989;340(6233):443-448
ASSOCIATION OF CLASS-I MAJOR HISTOCOMPATIBILITY HEAVY AND LIGHT-CHAINS INDUCED BY VIRAL PEPTIDES
TOWNSEND A; OHLEN C; BASTIN J; LJUNGGREN HG; FOSTER L; KARRE K
Journal article: NEUROLOGICAL SURGERY. 1989;17(8):717-723
[Experimental analysis of intracerebral natural resistance against H-2+ and H-2- lymphomas grafted into the brain].
Yamasaki T; Kikuchi H; Yamashita J; Ljunggren HG; Karre K; Klein G
Journal article: CELLULAR IMMUNOLOGY. 1989;120(2):387-395
ENHANCED H-2 EXPRESSION AND T-CELL-DEPENDENT REJECTION AFTER INTRACEREBRAL TRANSPLANTATION OF THE MURINE LYMPHOMA YAC-1
YAMASAKI T; LJUNGGREN HG; OHLEN C; KLEIN G; KARRE K
Journal article: JOURNAL OF IMMUNOLOGY. 1989;142(9):3336-3341
STUDIES OF SUBLINES SELECTED FOR LOSS OF HLA EXPRESSION FROM AN EBV-TRANSFORMED LYMPHOBLASTOID CELL-LINE - CHANGES IN SENSITIVITY TO CYTO-TOXIC T-CELLS ACTIVATED BY ALLOSTIMULATION AND NATURAL-KILLER CELLS ACTIVATED BY IFN OR IL-2
OHLEN C; BEJARANO MT; GRONBERG A; TORSTEINSDOTTIR S; FRANKSSON L; LJUNGGREN HG; KLEIN E; KLEIN G; KARRE K
Journal article: JOURNAL OF IMMUNOLOGY. 1989;142(8):2911-2917
MOLECULAR ANALYSIS OF H-2-DEFICIENT LYMPHOMA LINES - DISTINCT DEFECTS IN BIOSYNTHESIS AND ASSOCIATION OF MHC CLASS-I HEAVY-CHAINS AND BETA-2-MICROGLOBULIN OBSERVED IN CELLS WITH INCREASED SENSITIVITY TO NK CELL-LYSIS
LJUNGGREN HG; PAABO S; COCHET M; KLING G; KOURILSKY P; KARRE K
Journal article: NEUROLOGICAL SURGERY. 1989;17(3):229-237
[Molecular analysis of mouse major histocompatibility complex class I gene expression of tumors growing in the brain].
Yamasaki T; Kikuchi H; Yamashita J; Kärre K; Ljunggren HG; Klein G
Journal article: COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY. 1989;54:299-308
A MUTANT-CELL IN WHICH ASSOCIATION OF CLASS-I HEAVY AND LIGHT-CHAINS IS INDUCED BY VIRAL PEPTIDES
TOWNSEND A; OHLEN C; FOSTER L; BASTIN J; LJUNGGREN HG; KARRE K
Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 1988;168(4):1469-1474
NATURAL-RESISTANCE AGAINST LYMPHOMA GRAFTS CONVEYED BY H-2DD TRANSGENE TO C57BL MICE
HOGLUND P; LJUNGGREN HG; OHLEN C; AHRLUND-RICHTER L; SCANGOS G; BIEBERICH C; JAY G; KLEIN G; KARRE K
Journal article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 1988;80(4):263-269
EFFECTS OF DIMETHYL-SULFOXIDE TREATMENT ON H-2 EXPRESSION AND SUSCEPTIBILITY TO NK-MEDIATED OR CYTO-TOXIC LYMPHOCYTE-T-MEDIATED LYSIS OF THE YAC-1 LYMPHOMA AND ITS BETA-2-MICROGLOBULIN-DEFICIENT VARIANT
YAMASAKI T; KLEIN G; LJUNGGREN HG; HOGLUND P; OHLEN C; PETERSSON MGE; KARRE K
Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 1988;167(2):730-735
SELECTIVE ACCEPTANCE OF MHC CLASS-I DEFICIENT TUMOR GRAFTS IN THE BRAIN
LJUNGGREN HG; YAMASAKI T; COLLINS P; KLEIN G; KARRE K
Journal article: JOURNAL OF IMMUNOLOGY. 1988;140(2):671-678
AFFERENT AND EFFERENT CELLULAR INTERACTIONS IN NATURAL-RESISTANCE DIRECTED AGAINST MHC CLASS-I DEFICIENT TUMOR GRAFTS
LJUNGGREN HG; OHLEN C; HOGLUND P; YAMASAKI T; KLEIN G; KARRE K
Journal article: INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY. 1988;10:67
Effects of dimethyl sulfoxide (DMSO) treatment on H-2 expression and susceptibility to NK and CTL mediated lysis of YAC-1 lymphoma and its β2microglobulin (β2M) deficient variant
Yamasaki T; Kikuchi H; Yamashita J; Ljunggren HG; Kärre K; Klein G
Journal article: JOURNAL OF IMMUNOGENETICS. 1986;13(2-3):141-151
EXPERIMENTAL STRATEGIES AND INTERPRETATIONS IN THE ANALYSIS OF CHANGES IN MHC GENE-EXPRESSION DURING TUMOR PROGRESSION - OPPOSING INFLUENCES OF T-CELL AND NATURAL-KILLER MEDIATED RESISTANCE
LJUNGGREN HG; KARRE K
Journal article: NATURE. 1986;319(6055):675-678
SELECTIVE REJECTION OF H-2-DEFICIENT LYMPHOMA VARIANTS SUGGESTS ALTERNATIVE IMMUNE DEFENSE STRATEGY
KARRE K; LJUNGGREN HG; PIONTEK G; KIESSLING R
Journal article: JOURNAL OF IMMUNOLOGY. 1985;135(6):4281-4288
YAC-1 MHC CLASS-I VARIANTS REVEAL AN ASSOCIATION BETWEEN DECREASED NK SENSITIVITY AND INCREASED H-2 EXPRESSION AFTER INTERFERON TREATMENT OR INVIVO PASSAGE
PIONTEK GE; TANIGUCHI K; LJUNGGREN HG; GRONBERG A; KIESSLING R; KLEIN G; KARRE K
Journal article: JOURNAL OF EXPERIMENTAL MEDICINE. 1985;162(6):1745-1759
HOST-RESISTANCE DIRECTED SELECTIVELY AGAINST H-2-DEFICIENT LYMPHOMA VARIANTS - ANALYSIS OF THE MECHANISM
LJUNGGREN HG; KARRE K
Journal article: BRITISH JOURNAL OF NUTRITION. 1961;15:21-34
Basal metabolism in women with obesity and anorexia nervosa.
LJUNGGREN H; IKKOS D; LUFT R
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