Gunnar Norstedt

Iglesias-Gato D; Chuan Y-C; Wikstrom P; Augsten S; Jiang N; Niu Y; Seipel A; Danneman D; Vermeij M; Fernandez-Perez L; Jenster G; Egevad L; Norstedt G; Flores-Morales A

Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2013;172(3):490-499

The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation

Hu J; Kinn J; Zirakzadeh AA; Sherif A; Norstedt G; Wikstrom A-C; Winqvist O

Article: CLINICAL ENDOCRINOLOGY. 2012;77(2):288-295

Effects of oestrogen and testosterone therapy on serum metabolites in postmenopausal women

Zang H; Moritz T; Norstedt G; Hirschberg AL; Tollet-Egnell P

Article: FASEB JOURNAL. 2012;26(8):3282-3291

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice

Zadjali F; Santana-Farre R; Vesterlund M; Carow B; Mirecki-Garrido M; Hernandez-Hernandez I; Flodstrom-Tullberg M; Parini P; Rottenberg M; Norstedt G; Fernandez-Perez L; Flores-Morales A

Article: PHYTOTHERAPY RESEARCH. 2012;26(2):259-264

Androgen-independent Effects of Serenoa repens Extract (Prostasan®) on Prostatic Epithelial Cell Proliferation and Inflammation

Iglesias-Gato D; Carsten T; Vesterlund M; Pousette A; Schoop R; Norstedt G

Article: PLOS ONE. 2012;7(1):e30166

LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop

Hu J; Lou D; Carow B; Winerdal ME; Rottenberg M; Wikstrom A-C; Norstedt G; Winqvist O

Article: PLOS ONE. 2012;7(5):e37386

Influence of Neonatal Hypothyroidism on Hepatic Gene Expression and Lipid Metabolism in Adulthood

Santana-Farre R; Mirecki-Garrido M; Bocos C; Henriquez-Hernandez LA; Kahlon N; Herrera E; Norstedt G; Parini P; Flores-Morales A; Fernandez-Perez L

Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2011;127(3-5):269-275

Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D₃ with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells

Iglesias-Gato D; Zheng S; Flanagan JN; Jiang L; Kittaka A; Sakaki T; Yamamoto K; Itoh T; LeBrasseur NK; Norstedt G; Chen TC

Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2011;47(2):129-143

Sex-dependent hepatic transcripts and metabolites in the development of glucose intolerance and insulin resistance in Zucker diabetic fatty rats

Gustavsson C; Soga T; Wahlstrom E; Vesterlund M; Azimi A; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2011;6(9):e25358

The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

Vesterlund M; Zadjali F; Persson T; Nielsen ML; Kessler BM; Norstedt G; Flores-Morales A

Article: BMC BIOCHEMISTRY. 2010;11:38

Sex-different hepaticglycogen content and glucose output in rats

Gustavsson C; Yassin K; Wahlstrom E; Cheung L; Lindberg J; Brismar K; Ostenson C-G; Norstedt G; Tollet-Egnell P

Article: CLINICAL ENDOCRINOLOGY. 2010;72(6):800-806

The effect of in vivo growth hormone treatment on blood gene expression in adults with growth hormone deficiency reveals potential biomarkers to monitor growth hormone therapy

Fernandez-Perez L; Novoa J; Stahlberg N; Santana-Farre R; Boronat M; Marrero D; Henriquez-Hernandez L; Norstedt G; Flores-Morales A

Article: ONCOGENE. 2010;29(10):1531-1542

Ezrin mediates c-Myc actions in prostate cancer cell invasion

Chuan Y-C; Iglesias-Gato D; Fernandez-Perez L; Cedazo-Minguez A; Pang S-T; Norstedt G; Pousette A; Flores-Morales A

Article: LIPIDS. 2009;44(11):1011-1027

Cocoa Butter and Safflower Oil Elicit Different Effects on Hepatic Gene Expression and Lipid Metabolism in Rats

Gustavsson C; Parini P; Ostojic J; Cheung L; Hu J; Zadjali F; Tahir F; Brismar K; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2009;4(9):e7178

SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation

Hu J; Winqvist O; Flores-Morales A; Wikstroem A-C; Norstedt G

Article: BMC MOLECULAR BIOLOGY. 2009;10:13

Sex-different and growth hormone-regulated expression of microRNA in rat liver

Cheung L; Gustavsson C; Norstedt G; Tollet-Egnell P

Article: METABOLOMICS. 2008;4(3):273-282

Metabolomics as a tool to evaluate exercise-induced improvements in insulin sensitivity

Kuhl J; Moritz T; Wagner H; Stenlund H; Lundgren K; Bavenholm P; Efendic S; Norstedt G; Tollet-Egnell P

Article: NUCLEIC ACIDS RESEARCH. 2008;36(9):e53

Analysis of siRNA specificity on targets with double-nucleotide mismatches

Dahlgren C; Zhang H-Y; Du Q; Grahn M; Norstedt G; Wahlestedt C; Liang Z

Article: MUSCLE & NERVE. 2007;36(2):223-233

Iron load and redox stress in skeletal muscle of aged rats

Altun M; Edstrom E; Spooner E; Flores-Moralez A; Bergman E; Tollet-Egnell P; Norstedt G; Kessler BM; Ulfhake B

Article: BMC MOLECULAR BIOLOGY. 2007;8:60

Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver -: a role for growth hormone in alternative exon usage

Cheung L; Andersen M; Gustavsson C; Odeberg J; Fernandez-Perez L; Norstedt G; Tollet-Egnell P

Article: PLOS ONE. 2007;2(7):e610

MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?

Sonkoly E; Wei T; Janson PCJ; Saaf A; Lundeberg L; Tengvall-Linder M; Norstedt G; Alenius H; Homey B; Scheynius A; Stahle M; Pivarcsi A

Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2007;320(2):695-705

Role of pituitary hormones on 17α-ethinylestradiol-induced cholestasis in rat

Henriquez-Hernandez LA; Flores-Morales A; Santana-Farre R; Axelson M; Nilsson P; Norstedt G; Fernandez-Perez L

Article: MOLECULAR ENDOCRINOLOGY. 2007;21(1):293-311

In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver

Vidal OM; Merino R; Rico-Bautista E; Fernandez-Perez L; Chia DJ; Woelfle J; Ono M; Lenhard B; Norstedt G; Rotwein P; Flores-Morales A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(40):29938-29948

Androgen induction of prostate cancer cell invasion is mediated by ezrin

Chuan Y-C; Pang S-T; Cedazo-Minguez A; Norstedt G; Pousette A; Flores-Morales A

Article: PROSTATE. 2006;66(12):1235-1244

Proteomic comparison of prostate cancer cell lines LNCaP-FGC and LNCaP-r reveals heatshock protein 60 as a marker for prostate malignancy

Johansson B; Pourian MR; Chuan Y-C; Byman I; Bergh A; Pang S-T; Norstedt G; Bergman T; Pousette A

Article: PROSTATE. 2006;66(2):157-172

Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer

Pang ST; Weng WH; Flores-Morales A; Johansson B; Pourian MR; Nilsson P; Pousette Å; Larsson C; Norstedt G

Article: INTERNATIONAL JOURNAL OF ANDROLOGY. 2005;28(5):291-296

Androgens induce CD-9 in human prostate tissue

Chuan Y; Pang ST; Bergh A; Norstedt G; Pousette Å

Article: MOLECULAR ENDOCRINOLOGY. 2005;19(3):781-793

Suppressor of cytokine signaling-2 deficiency induces molecular and metabolic changes that partially overlap with growth hormone-dependent effects

Rico-Bautista E; Greenhalgh CJ; Tollet-Egnell P; Hilton DJ; Alexander WS; Norstedt G; Flores-Morales A

Article: JOURNAL OF CLINICAL INVESTIGATION. 2005;115(2):397-406

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Greenhalgh CJ; Rico-Bautista E; Lorentzon M; Thaus AL; Morgan PO; Willson TA; Zervoudakis P; Metcalf D; Street I; Nicola NA; Nash AD; Fabri LJ; Norstedt G; Ohlsson C; Flores-Morales A; Alexander WS; Hilton DJ

Article: ONCOLOGY REPORTS. 2004;11(6):1187-1192

Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer

Pang ST; Flores-Morales A; Skoog L; Chuan YC; Nordstedt G; Pousette Å

Article: ENDOCRINOLOGY. 2004;145(4):1972-1979

Female-predominant expression of fatty acid translocase/CD36 in rat and human liver

Ståhlberg N; Rico-Bautista E; Fisher RM; Wu XX; Cheung L; Flores-Morales A; Tybring G; Norstedt G; Tollet-Egnell P

Article: UROLOGY. 2004;63(3):609-612

Expression of ezrin in prostatic intraepithelial neoplasia

Pang ST; Fang XL; Valdman A; Norstedt G; Pousette Å; Egevad L; Ekman P

Article: PHYSIOLOGICAL GENOMICS. 2004;16(2):261-267

Growth hormone-mediated alteration of fuel metabolism in the aged rat as determined from transcript profiles

Tollet-Egnell P; Parini P; Ståhlberg N; Lönnstedt I; Lee NH; Rudling M; Flores-Morales A; Norstedt G

Article: JOURNAL OF LIPID RESEARCH. 2004;45(1):148-154

Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women

Linder K; Arner P; Flores-Morales A; Tollet-Egnell P; Norstedt G

Article: ENDOCRINOLOGY. 2003;144(11):4955-4966

Gene expression analysis of prostate hyperplasia in mice overexpressing the prolactin gene specifically in the prostate

Dillner K; Kindblom J; Flores-Morales A; Shao RJ; Törnell J; Norstedt G; Wennbo H

Article: BIOLOGY OF REPRODUCTION. 2003;69(4):1308-1317

Gene expression profiling of the effects of castration and estrogen treatment in the rat uterus

Wu XX; Pang ST; Sahlin L; Blanck A; Norstedt G; Flores-Morales A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(38):35988-35999

Development of pure prolactin receptor antagonists

Bernichtein S; Kayser C; Dillner K; Moulin S; Kopchick JJ; Martial JA; Norstedt G; Isaksson O; Kelly PA; Goffin V

Article: INTERNATIONAL JOURNAL OF CANCER. 2003;104(2):131-138

Differentially expressed transcripts in neoplastic hepatic nodules and neonatal rat liver studied by cDNA microarray analysis

Tellgren Å; Wood TJJ; Flores-Morales A; Torndal UB; Eriksson L; Norstedt G

Article: ENDOCRINOLOGY. 2002;143(12):4897-4906

Gene expression profiling of androgen deficiency predicts a pathway of prostate apoptosis that involves genes related to oxidative stress

Pang ST; Dillner K; Wu XX; Pousette Å; Norstedt G; Flores-Morales A

Article: PROSTATE. 2002;52(2):139-149

Molecular characterization of prostate hyperplasia in prolactin Transgenic mice by using cDNA representational difference analysis

Dillner K; Kindblom J; Flores-Morales A; Pang ST; Törnell J; Wennbo H; Norstedt G

Article: MOLECULAR ENDOCRINOLOGY. 2002;16(6):1257-1268

Patterns of liver gene expression governed by TRβ

Flores-Morales A; Gullberg H; Fernandez L; Ståhlberg N; Lee NH; Vennström B; Norstedt G

Article: MOLECULAR HUMAN REPRODUCTION. 2002;8(3):246-254

Identification of genes with higher expression in human uterine leiomyomas than in the corresponding myometrium

Wu XX; Blanck A; Norstedt G; Sahlin L; Flores-Morales A

Article: MOLECULAR ENDOCRINOLOGY. 2001;15(9):1471-1483

Endoplasmic reticulum stress prolongs GH-induced Janus kinase (JAK2)/signal transducer and activator of transcription (STAT5), signaling pathway

Flores-Morales A; Fernández L; Rico-Bautista E; Umana A; Negrín C; Zhang JG; Norstedt G

Article: ENDOCRINOLOGY. 2001;142(7):3163-3176

Microarray analysis of the in vivo effects of hypophysectomy and growth hormone treatment on gene expression in the rat

Flores-Morales A; Ståhlberg N; Tollet-Egnell P; Lundeberg J; Malek RL; Quackenbush J; Lee NH; Norstedt G

Article: MOLECULAR ENDOCRINOLOGY. 2001;15(2):308-318

Gene expression profile of the aging process in rat liver:: Normalizing effects of growth hormone replacement

Tollet-Egnell P; Flores-Morales A; Ståhlberg N; Malek RL; Lee N; Norstedt G

Article: NEW BIOTECHNOLOGY. 2000;17(1):1-9

A cDNA RDA protocol using solid-phase technology suited for analysis in small tissue samples

Odeberg J; Wood T; Blücher Å; Rafter J; Norstedt G; Lundeberg J

Article: GROWTH HORMONE & IGF RESEARCH. 2000;10(5):236-241

Comparison of STAT5 mRNA levels in GH-treated male and female rats analysed by a solution hybridization assay

Ortiz BL; Sánchez-Gómez M; Norstedt G

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2000;143(1):71-76

Characterisation of novel missense mutations in the GH receptor gene causing severe growth retardation

Enberg B; Luthman H; Segnestam K; Ritzén EM; Sundström M; Norstedt G

Article: ENDOCRINOLOGY. 2000;141(3):910-921

Differential cloning of growth hormone-regulated hepatic transcripts in the aged rat

Tollet-Egnell P; Flores-Morales A; Odeberg J; Lundeberg J; Norstedt G

Article: ENDOCRINOLOGY. 1999;140(8):3693-3704

Growth hormone regulation of SOCS-2, SOCS-3, and CIS messenger ribonucleic acid expression in the rat

Tollet-Egnell P; Flores-Morales A; Stavréus-Evers A; Sahlin L; Norstedt G

Article: ENDOCRINOLOGY. 1998;139(4):1815-1824

Desensitization of the growth hormone-induced Janus kinase 2 (Jak 2) signal transducer and activator of transcription 5 (Stat5)-signaling pathway requires protein synthesis and phospholipase C

Fernández L; Flores-Morales A; Lahuna O; Sliva D; Norstedt G; Haldosén LA; Mode A; Gustafsson J

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1998;138(1-2):1-10

In vitro interaction between STAT5 and JAK2;: dependence upon phosphorylation status of STAT5 and JAK2

Flores-Morales A; Pircher TJ; Silvennoinen O; Gustafsson J; Sanchez-Gomez M; Norstedt G; Haldosén LA; Wood TJJ

Article: ACTA ORTHOPAEDICA. 1997;68(6):586-592

Insulin-like growth factor I increases bone formation in old or corticosteroid treated rats

Prisell PT; Aspenberg P; Wikstrom B; Wredmark T; Norstedt G

Article: EXPERIMENTAL CELL RESEARCH. 1997;237(1):196-206

Mode of the autocrine/paracrine mechanism of growth hormone action

Liu ND; Mertani HC; Norstedt G; Törnell J; Lobie PE

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;133(2):169-176

Mitogen-activated protein kinase kinase inhibition decreases growth hormone stimulated transcription mediated by STAT5

Pircher TJ; FloresMorales A; Mui ALF; Saltiel AR; Norstedt G; Gustafsson JA; Haldosen LA

Article: ENDOCRINOLOGY. 1997;138(8):3207-3215

Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (Signal Transducer and Activator of Transcription-5)-mediated transcription

Goh ELK; Pircher TJ; Wood TJJ; Norstedt G; Graichen R; Lobie PE

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1997;130(1-2):69-81

Specificity of transcription enhancement via the STAT responsive element in the serine protease inhibitor 2.1 promoter

Wood TJJ; Sliva D; Lobie PE; Goullieux F; Mui AL; Groner B; Norstedt G; Haldosen LA

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(50):32197-32203

Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.

Sundström M; Lundqvist T; Rödin J; Giebel LB; Milligan D; Norstedt G

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(46):29415-29421

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

Argetsinger LS; Norstedt G; Billestrup N; White MF; CarterSu C

Article: ENDOCRINOLOGY. 1996;137(9):4037-4045

Constitutive nuclear localization of Janus kinases 1 and 2

Lobie PE; Ronsin B; Silvennoinen O; Haldosen LA; Norstedt G; Morel G

Article: MOLECULAR ENDOCRINOLOGY. 1996;10(5):519-533

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH

Smit LS; Meyer DJ; Billestrup N; Norstedt G; Schwartz J; CarterSu C

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(37):21745-21750

REQUIREMENT OF TYROSINE-RESIDUE-333 AND TYROSINE-RESIDUE-338 OF THE GROWTH-HORMONE (GH) RECEPTOR FOR SELECTED GH-STIMULATED FUNCTION

LOBIE PE; ALLEVATO G; NIELSEN JH; NORSTEDT G; BILLESTRUP N

Article: ENDOCRINOLOGY. 1995;136(9):3767-3773

GROWTH-HORMONE SPECIFICALLY STIMULATES THE EXPRESSION OF LOW-DENSITY-LIPOPROTEIN RECEPTORS IN HUMAN HEPATOMA-CELLS

PARINI P; ANGELIN B; LOBIE PE; NORSTEDT G; RUDLING M

Article: PEDIATRIC RESEARCH. 1995;38(3):418-421

GROWTH-HORMONE (GH) TREATMENT UP-REGULATES GH RECEPTOR MESSENGER-RNA LEVELS IN ADIPOCYTES FROM PATIENTS WITH GH DEFICIENCY AND PRADER-WILLI-SYNDROME

KAMEL A; MARGERY V; NORSTEDT G; THOREN M; LINDGREN AC; BRONNEGARD M; MARCUS C

Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 1995;113(1):11-17

HORMONAL-REGULATION OF THE FEMALE ENRICHED GH RECEPTOR-BINDING PROTEIN MESSENGER-RNA IN RAT-LIVER

AHLGREN R; NORSTEDT G; BAUMBACH WR; MODE A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(29):17210-17214

IDENTIFICATION OF PHENYLALANINE-346 IN THE RAT GROWTH-HORMONE RECEPTOR AS BEING CRITICAL FOR LIGAND-MEDIATED INTERNALIZATION AND DOWN-REGULATION

ALLEVATO G; BILLESTRUP N; GOUJON L; GALSGAARD ED; NORSTEDT G; POSTELVINAY MC; KELLY PA; NIELSEN JH

Article: EMBO JOURNAL. 1995;14(9):2005-2013

PROLACTIN, GROWTH-HORMONE, ERYTHROPOIETIN AND GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR INDUCE MGF-STAT5 DNA-BINDING ACTIVITY

GOUILLEUX F; PALLARD C; DUSANTERFOURT I; WAKAO H; HALDOSEN LA; NORSTEDT G; LEVY D; GRONER B

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(16):9448-9453

MEDIATION OF GROWTH HORMONE-DEPENDENT TRANSCRIPTIONAL ACTIVATION BY MAMMARY-GLAND FACTOR STAT-5

WOOD TJJ; SLIVA D; LOBIE PE; PIRCHER TJ; GOUILLEUX F; WAKAO H; GUSTAFSSON JA; GRONER B; NORSTEDT G; HALDOSEN LA

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(13):7587-7593

GROWTH-HORMONE PROMOTED TYROSYL PHOSPHORYLATION OF SHC PROTEINS AND SHC ASSOCIATION WITH GRB2

VANDERKUUR J; ALLEVATO G; BILLESTRUP N; NORSTEDT G; CARTERSU C

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