Felix Haglund de Flon
Senior Forskare | Docent
E-postadress: felix.haglund@ki.se
Besöksadress: J6:20 BioClinicum, Akademiska stråket 1, 17164 SOLNA
Postadress: K7 Onkologi-Patologi, K7 Forskning Larsson Olle Haglund, 171 77 Stockholm
Om mig
- *Associate Professor of Experimental Pathology*, Karolinska Institutet
*Head of Molecular Cancer Diagnostics* (Molecular Pathology), Karolinska
University Hospital Solna
M.D. / Ph.D., Consultant Clinical Pathologist
Thesis of the Year, Swedish Association of Pathology 2014
Young Researcher Award, Euro Ewing Consortium 2018
MD, Karolinska Institutet 2012
PhD, Karolinska Institutet 2013
Licenced physician 2014
Associate Progessor of Experimental Pathology, Karolinska Institutet 2019
Consultant Clinical Pathologist 2019
Forskningsbeskrivning
- - Precision cancer genomics
- Sarcoma genomics and biology
Recent publications:
Sarcoma Tumor Microenvironment. [1] Tsagozis P, Gonzalez-Molina J,
Georgoudaki AM, Lehti K, Carlson J, Lundqvist A, *Haglund F*, Ehnman M.Adv
Exp Med Biol. 2020 - 1296:319-348. doi: 10.1007/978-3-030-59038-3_20.
PMID: 34185302
Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing
Sarcoma. [2] Chen Y, Su H, Su Y, Zhang Y, Lin Y, *Haglund F. *Cancers
(Basel). 2021 Jul 25 - 13(15):3736. doi: 10.3390/cancers13153736.
PMID: 34359637
Follicular Helper T-Cell-Based Classification of Endometrial Cancer Promotes
Precise Checkpoint Immunotherapy and Provides Prognostic Stratification.
[3] Chen Y, You S, Li J, Zhang Y, Kokaraki G, Epstein E, Carlson J, Huang
WK, *Haglund F. *Front Immunol. 2022 Jan 7 - 12:788959. doi:
10.3389/fimmu.2021.788959. eCollection 2021 PMID: 35069566
Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing
Sarcoma. [4] Chen Y, Su H, Su Y, Zhang Y, Lin Y, *Haglund F. *Cancers
(Basel). 2021 Jul 25 - 13(15):3736. doi:
10.3390/cancers13153736.PMID: 34359637 Free PMC article.
TERT promoter mutation is an objective clinical marker for disease
progression in chondrosarcoma. [5] Zhang Y, Chen Y, Yang C, Seger N, Hesla
AC, Tsagkozis P, Larsson O, Lin Y, *Haglund F. *Mod Pathol. 2021
Nov - 34(11):2020-2027. doi: 10.1038/s41379-021-00848-0. Epub 2021 Jun 9.
PMID: 34108637
CD11c-CD8 Spatial Cross Presentation: A Novel Approach to Link Immune
Surveillance and Patient Survival in Soft Tissue Sarcoma. [6] Su Y,
Tsagkozis P, Papakonstantinou A, Tobin NP, Gultekin O, Malmerfelt A,
Ingelshed K, Neo SY, Lundquist J, Chaabane W, Nisancioglu MH, Leiss LW,
Östman A, Bergh J, Sedimbi S, Lehti K, Lundqvist A, Stragliotto
CL, *Haglund F*, Ehnman M.Cancers (Basel). 2021 Mar 9 - 13(5):1175. doi:
10.3390/cancers13051175.PMID: 33803245
Clear-cell chondrosarcomas: Fine-needle aspiration cytology, radiological
findings, and patient demographics of a rare entity. [7] Zhang Y, Alagic Z,
Tani E, Skorpil M, Tsagkozis P, *Haglund F.*Diagn Cytopathol. 2021
Jan - 49(1):46-53. doi: 10.1002/dc.24582. Epub 2020 Aug 12.PMID: 32786062
Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage
in a variety of human cancers. [8] Yang C, Zhang Y, Chen Y, Ragaller F, Liu
M, Corvigno S, Dahlstrand H, Carlson J, Chen Z, Näsman A, Waraky A, Lin Y,
Larsson O, *Haglund F.*PLoS One. 2020 Jul 23 - 15(7):e0236291. doi:
10.1371/journal.pone.0236291. eCollection 2020.PMID: 32701997
Transcriptome profiling of Ewing sarcomas - treatment resistance pathways and
IGF-dependency. [9] Chen Y, Hesla AC, Lin Y, Ghaderi M, Liu M, Yang C, Zhang
Y, Tsagkozis P, Larsson O, *Haglund F.*Mol Oncol. 2020 May - 14(5):1101-1117.
doi: 10.1002/1878-0261.12655. Epub 2020 Mar 13.PMID: 32115849
[1] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34185302/
[2] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34359637/
[3] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/35069566/
[4] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34359637/
[5] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34108637/
[6] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/33803245/
[7] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32786062/
[8] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32701997/
[9] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32115849/
Artiklar
- Article: CLINICAL CANCER RESEARCH. 2024;30(12):2647-2658
- Article: INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY. 2024;43(1):78-89
- Article: ONCOIMMUNOLOGY. 2023;12(1):2233402
- Article: ACTA ONCOLOGICA. 2023;62(12):1808-1814
- Article: BRITISH JOURNAL OF SURGERY. 2023;110(12):1857-1862
- Article: GENES CHROMOSOMES AND CANCER. 2023;62(10):607-610
- Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(3):103401
- Article: BRITISH JOURNAL OF CANCER. 2022;127(10):1793-1798
- Article: INTERNATIONAL JOURNAL OF CANCER. 2022;151(6):906-913
- Article: JOURNAL OF SURGICAL ONCOLOGY. 2022;126(4):787-792
- Article: MODERN PATHOLOGY. 2022;35(9):1204-1211
- Article: CANCER MEDICINE. 2022;11(14):2729-2734
- Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(5):e004592
- Article: JOURNAL OF CLINICAL PATHOLOGY. 2022;75(5):302-309
- Article: BIOMOLECULES. 2022;12(2):292
- Article: NATURE CANCER. 2022;3(2):251-261
- Article: BIOMOLECULES. 2021;11(11):1721
- Article: MODERN PATHOLOGY. 2021;34(11):2020-2027
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(11):3265-3282
- Article: ONCOLOGY REPORTS. 2021;46(2):168
- Article: CANCERS. 2021;13(15):3736
- Article: HEAD AND NECK PATHOLOGY. 2021;15(2):628-637
- Article: LAKARTIDNINGEN. 2021;118:20209
- Article: CANCERS. 2021;13(5):1175
- Article: ONCOLOGY LETTERS. 2021;21(2):120
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:719105
- Article: HUMAN CELL. 2021;34(1):238-245
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:788959
- Article: DIAGNOSTIC CYTOPATHOLOGY. 2021;49(1):46-53
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(10):5508-5522
- Article: MOLECULAR ONCOLOGY. 2020;14(5):1101-1117
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(3):1185-1198
- Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2020;1296:319-348
- Article: PLOS ONE. 2020;15(7):e0236291
- Article: INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY. 2019;27(8):919-922
- Article: GENES CHROMOSOMES AND CANCER. 2019;58(10):731-736
- Article: CYTOPATHOLOGY. 2019;30(5):504-509
- Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2019;68(6):927-936
- Article: MODERN PATHOLOGY. 2018;31(12):1834-1841
- Article: JOURNAL OF CLINICAL PATHOLOGY. 2018;71(9):832-839
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2018;179(2):85-95
- Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;470:84-95
- Article: CANCER CYTOPATHOLOGY. 2018;126(1):36-43
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2017;177(6):445-453
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(44):18227-18239
- Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2017;232(10):2722-2730
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2017;109(3):djw236-14
- Article: ENDOCRINE PATHOLOGY. 2016;27(4):346-351
- Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2016;174(5):583-590
- Article: GENES CHROMOSOMES AND CANCER. 2015;54(9):542-554
- Article: ENDOCRINE CONNECTIONS. 2015;4(1):76-85
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2012;97(12):4631-4639
- Article: FAMILIAL CANCER. 2012;11(3):355-362
- Article: ENDOCRINE-RELATED CANCER. 2012;19(3):389-407
- Article: PLOS ONE. 2012;7(9):e46325
- Article: PLOS ONE. 2012;7(5):e36448
- Article: VIRCHOWS ARCHIV. 2011;459(1):47-53
- Article: ENDOCRINE PATHOLOGY. 2010;21(3):166-177
- Article: PLOS ONE. 2010;5(3):e9472
- Article: ENDOCRINE-RELATED CANCER. 2007;14(2):501-512
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;34(2):481-492
- Visa fler
Alla övriga publikationer
- Review: JOURNAL OF INTERNAL MEDICINE. 2023;294(6):690-707
- Letter: CANCER COMMUNICATIONS. 2023;43(7):855-859
- Meeting abstract: CANCER RESEARCH. 2023;83(7):4578
- Conference publication: ANNALS OF ONCOLOGY. 2022;33(7):S1087
- Corrigendum: NATURE CANCER. 2022;3(5):649
- Review: JOURNAL OF MEDICAL CASE REPORTS. 2020;14(1):44
- Review: CURRENT ONCOLOGY REPORTS. 2019;21(10):90
- Preprint: SSRN ELECTRONIC JOURNAL. 2019
- Letter: ENDOCRINE PATHOLOGY. 2018;29(4):380-383
- Review: INTERVENTIONAL NEURORADIOLOGY. 2018;24(3):277-283
- Published conference paper: SURGERY. 2017;161(6):1667-1674
- Letter: CLINICAL ENDOCRINOLOGY. 2016;84(4):632-634
- Letter: ENDOCRINE-RELATED CANCER. 2015;22(3):L9-L11
- Thesis / dissertation: 2013
- Letter: CLINICAL ENDOCRINOLOGY. 2010;73(4):552-553
- Conference publication: CANCER RESEARCH. 2009;69
Anställningar
- Senior Forskare, Onkologi-Patologi, Karolinska Institutet, 2022-
Examina och utbildning
- Docent, Experimentell patologi, Karolinska Institutet, 2019
- Medicine Doktorsexamen, Institutionen för onkologi-patologi, Karolinska Institutet, 2013
- Läkarexamen, Karolinska Institutet, 2012