Felix Haglund de Flon

Felix Haglund de Flon

Senior Forskare | Docent
E-postadress: felix.haglund@ki.se
Besöksadress: J6:20 BioClinicum, Akademiska stråket 1, 17164 Solna
Postadress: K7 Onkologi-Patologi, K7 Forskning Haglund, 171 77 Stockholm
Del av:

Om mig

  • *Associate Professor of Experimental Pathology*, Karolinska Institutet
    *Head of Molecular Cancer Diagnostics* (Molecular Pathology), Karolinska
    University Hospital Solna
    M.D. / Ph.D., Consultant Clinical Pathologist
    Thesis of the Year, Swedish Association of Pathology 2014
    Young Researcher Award, Euro Ewing Consortium 2018
    MD, Karolinska Institutet 2012
    PhD, Karolinska Institutet 2013
    Licenced physician 2014
    Associate Progessor of Experimental Pathology, Karolinska Institutet 2019
    Consultant Clinical Pathologist 2019

Forskningsbeskrivning

  • - Precision cancer genomics
    - Sarcoma genomics and biology
    Recent publications:
    Sarcoma Tumor Microenvironment. [1] Tsagozis P, Gonzalez-Molina J,
    Georgoudaki AM, Lehti K, Carlson J, Lundqvist A, *Haglund F*, Ehnman M.Adv
    Exp Med Biol. 2020;1296:319-348. doi: 10.1007/978-3-030-59038-3_20.
    PMID: 34185302
    Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing
    Sarcoma. [2] Chen Y, Su H, Su Y, Zhang Y, Lin Y, *Haglund F. *Cancers
    (Basel). 2021 Jul 25;13(15):3736. doi: 10.3390/cancers13153736.
    PMID: 34359637
    Follicular Helper T-Cell-Based Classification of Endometrial Cancer Promotes
    Precise Checkpoint Immunotherapy and Provides Prognostic Stratification.
    [3] Chen Y, You S, Li J, Zhang Y, Kokaraki G, Epstein E, Carlson J, Huang
    WK, *Haglund F. *Front Immunol. 2022 Jan 7;12:788959. doi:
    10.3389/fimmu.2021.788959. eCollection 2021 PMID: 35069566
    Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing
    Sarcoma. [4] Chen Y, Su H, Su Y, Zhang Y, Lin Y, *Haglund F. *Cancers
    (Basel). 2021 Jul 25;13(15):3736. doi:
    10.3390/cancers13153736.PMID: 34359637 Free PMC article.
    TERT promoter mutation is an objective clinical marker for disease
    progression in chondrosarcoma. [5] Zhang Y, Chen Y, Yang C, Seger N, Hesla
    AC, Tsagkozis P, Larsson O, Lin Y, *Haglund F. *Mod Pathol. 2021
    Nov;34(11):2020-2027. doi: 10.1038/s41379-021-00848-0. Epub 2021 Jun 9.
    PMID: 34108637
    CD11c-CD8 Spatial Cross Presentation: A Novel Approach to Link Immune
    Surveillance and Patient Survival in Soft Tissue Sarcoma. [6] Su Y,
    Tsagkozis P, Papakonstantinou A, Tobin NP, Gultekin O, Malmerfelt A,
    Ingelshed K, Neo SY, Lundquist J, Chaabane W, Nisancioglu MH, Leiss LW,
    Östman A, Bergh J, Sedimbi S, Lehti K, Lundqvist A, Stragliotto
    CL, *Haglund F*, Ehnman M.Cancers (Basel). 2021 Mar 9;13(5):1175. doi:
    10.3390/cancers13051175.PMID: 33803245
    Clear-cell chondrosarcomas: Fine-needle aspiration cytology, radiological
    findings, and patient demographics of a rare entity. [7] Zhang Y, Alagic Z,
    Tani E, Skorpil M, Tsagkozis P, *Haglund F.*Diagn Cytopathol. 2021
    Jan;49(1):46-53. doi: 10.1002/dc.24582. Epub 2020 Aug 12.PMID: 32786062
    Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage
    in a variety of human cancers. [8] Yang C, Zhang Y, Chen Y, Ragaller F, Liu
    M, Corvigno S, Dahlstrand H, Carlson J, Chen Z, Näsman A, Waraky A, Lin Y,
    Larsson O, *Haglund F.*PLoS One. 2020 Jul 23;15(7):e0236291. doi:
    10.1371/journal.pone.0236291. eCollection 2020.PMID: 32701997
    Transcriptome profiling of Ewing sarcomas - treatment resistance pathways and
    IGF-dependency. [9] Chen Y, Hesla AC, Lin Y, Ghaderi M, Liu M, Yang C, Zhang
    Y, Tsagkozis P, Larsson O, *Haglund F.*Mol Oncol. 2020 May;14(5):1101-1117.
    doi: 10.1002/1878-0261.12655. Epub 2020 Mar 13.PMID: 32115849
    [1] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34185302/
    [2] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34359637/
    [3] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/35069566/
    [4] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34359637/
    [5] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/34108637/
    [6] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/33803245/
    [7] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32786062/
    [8] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32701997/
    [9] https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/32115849/

Artiklar

Alla övriga publikationer

Anställningar

  • Senior Forskare, Onkologi-Patologi, Karolinska Institutet, 2022-

Examina och utbildning

  • Docent, Experimentell patologi, Karolinska Institutet, 2019
  • Medicine Doktorsexamen, Institutionen för onkologi-patologi, Karolinska Institutet, 2013
  • Läkarexamen, Karolinska Institutet, 2012

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