Eric Herlenius

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Nuvarande Position och Uppdrag:
Professor i Pediatrik, Karolinska Institutet
Överläkare i barnmedicin, Astrid Lindgrens barnsjukhus
FoUU-ansvarig vid Barnakut- och infektionssjukvård, Tema Barn- och Kvinnosjukvård, Karolinska universitetssjukhuset
Ledamot Docenturnämnden KI 2023-
Ledamot Nomineringsförsamlingen KI 2023-
Vice Ordf. Vetenskapsrådet beredningsgrupp MH-07: Kvinnor och Barns Hälsa 2021-2022
KI ansvarig Rekrytering ST-Pediatrik, Karolinska Universitets sjukhuset 2012-2022

Artiklar

Journal article: BIOETHICS OPEN RESEARCH. 2024;2:3
Systematic review of ethics and legislation of a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Herlenius E
Journal article: BIOETHICS OPEN RESEARCH. 2024;2:3
Systematic review of ethics and legislation of a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Herlenius E
Journal article: BMC DIGITAL HEALTH. 2024;2(1):76
Necessity for a global patient co-owned cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Ashrafian H; Herlenius E
Journal article: BMC DIGITAL HEALTH. 2024;2(1):75
Technical sandbox for a Global Patient co-Owned Cloud (GPOC)
Davids J; ElSharkawy M; Ashrafian H; Herlenius E; Lidströmer N
Journal article: BMC DIGITAL HEALTH. 2024;2(1):51
A summit on a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Ashrafian H; Herlenius E
Article: STAR PROTOCOLS. 2024;5(1):102908
Protocol to dissect and dissociate the mouse brainstem for single-cell RNA-seq applications
Phillips WS; Ramadan N; Samara A; Herlenius E
Article: NATURE COMMUNICATIONS. 2024;15(1):2186
Systematic review and meta-analysis for a Global Patient co-Owned Cloud (GPOC).
Lidströmer N; Davids J; ElSharkawy M; Ashrafian H; Herlenius E
Article: FRONTIERS IN CELLULAR NEUROSCIENCE. 2024;18:1408607
Astrocytic Calcium Signaling Toolkit (astroCaST): efficient analysis of dynamic astrocytic calcium events
Reising JP; Gonzalez-Sanchez AC; Samara A; Herlenius E
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2023;112(7):1443-1452
Weight a minute: The smaller and more immature, the more predictable the autonomic regulation?
Stalhammar AM; Honore A; Adolphson K; Forsberg D; Herlenius E; Jost K
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2023;112(4):686-696
Vital sign-based detection of sepsis in neonates using machine learning
Honore A; Forsberg D; Adolphson K; Chatterjee S; Jost K; Herlenius E
Article: FRONTIERS IN PEDIATRICS. 2023;11:1225294
Mechanical ventilation induces brainstem inflammation in preterm fetal sheep
Vidinopoulos K; Azman Z; Somers A; Zahra VA; Thiel A; Lu H; Pham Y; Tran NT; Allison BJ; Herlenius E; Hooper S; Galinsky R; Polglase GR
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1151-1161
Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function
Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Ottosson V; Forsberg D; Thorlacius GE; Biavati L; Strandberg L; Mofors J; Ramskold D; Ruhrmann S; Meneghel L; Nyberg W; Espinosa A; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2022;111(5):961-970
Proteomic profiles in cerebrospinal fluid predicted death and disability in term infants with perinatal asphyxia: A pilot study
Leifsdottir K; Thelin EP; Lassaren P; Siljehav V; Nilsson P; Eksborg S; Herlenius E
Article: FRONTIERS IN PEDIATRICS. 2022;10:921444
The cerebrospinal fluid proteome of preterm infants predicts neurodevelopmental outcome
Leifsdottir K; Jost K; Siljehav V; Thelin EP; Lassaren P; Nilsson P; Haraldsson A; Eksborg S; Herlenius E
Article: FRONTIERS IN NEURAL CIRCUITS. 2022;16:826497
Prostaglandin E2 Exerts Biphasic Dose Response on the PreBotzinger Complex Respiratory-Related Rhythm
Reising JP; Phillips WS; Ramadan N; Herlenius E
Article: FRONTIERS IN PHYSIOLOGY. 2022;13:841229
Increased Prostaglandin E2 in Brainstem Respiratory Centers Is Associated With Inhibition of Breathing Movements in Fetal Sheep Exposed to Progressive Systemic Inflammation
Stojanovska V; Atta J; Kelly SB; Zahra VA; Matthews-Staindl E; Nitsos I; Moxham A; Pham Y; Hooper SB; Herlenius E; Galinsky R; Polglase GR
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(10):2802-2804
Reduction in paediatric emergency visits during the COVID-19 pandemic in a region with open preschools and schools
Rhedin SA; Rinder MR; Hildenwall H; Herlenius E; Hertting O; Luthander J; Melen E; Nijman R; Olsson-Akefeldt S; Alfven T
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):312
Presynaptic dysfunction inCASK-related neurodevelopmental disorders
Becker M; Mastropasqua F; Reising JP; Maier S; Ho M-L; Rabkina I; Li D; Neufeld J; Ballenberger L; Myers L; Moritz V; Kele M; Wincent J; Willfors C; Sitnikov R; Herlenius E; Anderlid B-M; Falk A; Bolte S; Tammimies K
Article: FRONTIERS IN PHYSIOLOGY. 2020;11:624625
Is There an Effect of Fetal Mesenchymal Stem Cells in the Mother-Fetus Dyad in COVID-19 Pregnancies and Vertical Transmission?
Samara A; Herlenius E
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2019;108(10):1879-1886
Urinary PGE₂ metabolite levels in hospitalised infants with infections compared to age-matched controls
Hamrin J; Perez-Manzo M; Idborg H; Jakobsson P-J; Bjork L; Eriksson M; Nilsson A; Herlenius E
Article: FRONTIERS IN PHYSIOLOGY. 2019;10:307
Cognitive Development Trajectories in Preterm Children With Very Low Birth Weight Longitudinally Followed Until 11 Years of Age
Stalnacke SR; Tessma M; Bohm B; Herlenius E
Article: JOURNAL OF NEUROINFLAMMATION. 2018;15(1):223
Fas-ligand and interleukin-6 in the cerebrospinal fluid are early predictors of hypoxic-ischemic encephalopathy and long-term outcomes after birth asphyxia in term infants
Leifsdottir K; Mehmet H; Eksborg S; Herlenius E
Article: PEDIATRICS. 2018;141(5):e20174047
Neurobehavioral Outcomes 11 Years After Neonatal Caffeine Therapy for Apnea of Prematurity
Muerner-Lavanchy IM; Doyle LW; Schmidt B; Roberts RS; Asztalos EV; Costantini L; Davis PG; Dewey D; D'Ilario J; Grunau RE; Moddemann D; Nelson H; Ohlsson A; Solimano A; Tin W; Anderson PJ
Article: ELIFE. 2017;6:e29566
Astrocytes release prostaglandin E2 to modify respiratory network activity
Forsberg D; Ringstedt T; Herlenius E
Article: CURRENT PROTOCOLS IN STEM CELL BIOLOGY. 2017;42:2D.13.1-2D.13.30
Functional Stem Cell Integration into Neural Networks Assessed by Organotypic Slice Cultures.
Forsberg D; Thonabulsombat C; Jäderstad J; Jäderstad LM; Olivius P; Herlenius E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(32):E6603-E6612
Rho-associated kinase is a therapeutic target in neuroblastoma
Dyberg C; Fransson S; Andonova T; Sveinbjornsson B; Lannerholm-Palm J; Olsen TK; Forsberg D; Herlenius E; Martinsson T; Brodin B; Kogner P; Johnsen JI; Wickstrom M
Article: JAMA PEDIATRICS. 2017;171(6):564-572
Academic Performance, Motor Function, and Behavior 11 Years After Neonatal Caffeine Citrate Therapy for Apnea of Prematurity An 11-Year Follow-up of the CAP Randomized Clinical Trial
Schmidt B; Roberts RS; Anderson PJ; Asztalos EV; Costantini L; Davis PG; Dewey D; D'Ilario J; Doyle LW; Grunau RE; Moddemann D; Nelson H; Ohlsson A; Solimano A; Tin W
Article: ELIFE. 2016;5:e14170
CO₂-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture
Forsberg D; Horn Z; Tserga E; Smedler E; Silberberg G; Shvarev Y; Kaila K; Uhlen P; Herlenius E
Article: ARCHIVES DE PEDIATRIE. 2016;23(3):234-240
Hospital readmission after postpartum discharge of tern newborns in two maternity wards in Stockholm and Marseille
Boubred F; Herlenius E; Andres V; des Robert C; Marchini G
Article: JOURNAL OF PEDIATRICS. 2015;167(6):1207-13.e3
Prostaglandin E₂ Mediates Cardiorespiratory Disturbances during Infection in Neonates
Siljehav V; Hofstetter AM; Leifsdottir K; Herlenius E
Article: JOURNAL OF PEDIATRICS. 2015;167(5):982-6.e2
Prediction of Late Death or Disability at Age 5 Years Using a Count of 3 Neonatal Morbidities in Very Low Birth Weight Infants
Schmidt B; Roberts RS; Davis PG; Doyle LW; Asztalos EV; Opie G; Bairam A; Solimano A; Arnon S; Sauve RS
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2015;104(11):1077-1083
Extremely preterm infants who are small for gestational age have a high risk of early hypophosphatemia and hypokalemia
Boubred F; Herlenius E; Bartocci M; Jonsson B; Vanpee M
Article: NEUROREPORT. 2015;26(15):928-936
Adult neural precursor cells form connexin-dependent networks that improve their survival
Ravella A; Ringstedt T; Brion J-P; Pandolfo M; Herlenius E
Article: ARCHIVES OF DISEASE IN CHILDHOOD. 2015;100(8):748-753
Predicting severe motor impairment in preterm children at age 5 years
Synnes A; Anderson PJ; Grunau RE; Dewey D; Moddemann D; Tin W; Davis PG; Doyle LW; Foster G; Khairy M; Nwaesei C; Schmidt B
Article: JOURNAL OF PEDIATRICS. 2015;166(4):870-6.e1-2-U158
Social Variables Predict Gains in Cognitive Scores across the Preschool Years in Children with Birth Weights 500 to 1250 Grams
Manley BJ; Roberts RS; Doyle LW; Schmidt B; Anderson PJ; Barrington KJ; Bohm B; Golan A; van Wassenaer-Leemhuis AG; Davis PG
Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2014;91(6):269-275
Evaluation of urinary prostaglandin E₂ metabolite as a biomarker in infants with fever due to viral infection
Idborg H; Pawelzik S-C; Perez-Manso M; Bjork L; Hamrin J; Herlenius E; Jakobsson P-J
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2014;117(9):1027-1036
Il-1β and prostaglandin E₂ attenuate the hypercapnic as well as the hypoxic respiratory response via prostaglandin E receptor type 3 in neonatal mice
Siljehav V; Shvarev Y; Herlenius E
Article: JOURNAL OF PEDIATRICS. 2014;165(2):356-359.e2
Reduction in Developmental Coordination Disorder with Neonatal Caffeine Therapy
Doyle LW; Schmidt B; Anderson PJ; Davis PG; Moddemann D; Grunau RE; O'Brien K; Sankaran K; Herlenius E; Roberts R
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2013;102(11):1041-1047
PGE₂ - metabolite levels in CSF correlate to HIE score and outcome after perinatal asphyxia
Bjork L; Leifsdottir K; Saha S; Herlenius E
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2013;102(7):680-688
Unexpected collapse of healthy newborn infants: risk factors, supervision and hypothermia treatment
Pejovic NJ; Herlenius E
Article: TRANSLATIONAL STROKE RESEARCH. 2013;4(2):236-247
Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures
Herlenius E; Kuhn P
Article: CURRENT PROTOCOLS IN STEM CELL BIOLOGY. 2012;Chapter 2:Unit-2D.13
Functional stem cell integration assessed by organotypic slice cultures.
Herlenius E; Thonabulsombat C; Forsberg D; Jäderstad J; Jäderstad LM; Björk L; Olivius P
Article: PEDIATRIC RESEARCH. 2012;72(5):460-467
mPGES-1 and prostaglandin E₂: vital role in inflammation, hypoxic response, and survival
Siljehav V; Hofstetter AO; Jakobsson P-J; Herlenius E
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(3):448-454
Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model
Ambrosi A; Dzikaite V; Park J; Strandberg L; Kuchroo VK; Herlenius E; Wahren-Herlenius M
Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2012;307(3):275-282
Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity
Schmidt B; Anderson PJ; Doyle LW; Dewey D; Grunau RE; Asztalos EV; Davis PG; Tin W; Moddemann D; Solimano A; Ohlsson A; Barrington KJ; Roberts RS
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;90(1):152-160
PRRT2 Mutations Cause Benign Familial Infantile Epilepsy and Infantile Convulsions with Choreoathetosis Syndrome
Heron SE; Grinton BE; Kivity S; Afawi Z; Zuberi SM; Hughes JN; Pridmore C; Hodgson BL; Iona X; Sadleir LG; Pelekanos J; Herlenius E; Goldberg-Stern H; Bassan H; Haan E; Korczyn AD; Gardner AE; Corbett MA; Gecz J; Thomas PQ; Mulley JC; Berkovic SF; Scheffer IE; Dibbens LM
Article: JOURNAL OF PEDIATRICS. 2011;159(4):546-550
Impact of Delivery Room Resuscitation on Outcomes up to 18 Months in Very Low Birth Weight Infants
DeMauro SB; Roberts RS; Davis P; Alvaro R; Bairam A; Schmidt B
Article: EXPERIMENTAL CELL RESEARCH. 2011;317(1):70-81
Dynamic changes in connexin expression following engraftment of neural stem cells to striatal tissue
Jaderstad J; Jaderstad LM; Herlenius E
Article: PEDIATRICS. 2011;127(1):E146-E155
Economic Evaluation of Caffeine for Apnea of Prematurity
Dukhovny D; Lorch SA; Schmidt B; Doyle LW; Kok JH; Roberts RS; Kamholz KL; Wang N; Mao W; Zupancic JAF
Article: NEUROREPORT. 2010;21(17):1126-1132
Hypoxic preconditioning increases gap-junctional graft and host communication
Jaderstad J; Brismar H; Herlenius E
Article: REGENERATIVE MEDICINE. 2010;5(6):901-917
Graft and host interactions following transplantation of neural stem cells to organotypic striatal cultures
Jaderstad LM; Jaderstad J; Herlenius E
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(11):5184-5189
Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host
Jaderstad J; Jaderstad LM; Li J; Chintawar S; Salto C; Pandolfo M; Ourednik V; Teng YD; Sidman RL; Arenas E; Snyder EY; Herlenius E
Article: JOURNAL OF PEDIATRICS. 2010;156(3):382-U73
Caffeine for Apnea of Prematurity Trial: Benefits May Vary in Subgroups
Davis PG; Schmidt B; Roberts RS; Doyle LW; Asztalos E; Haslam R; Sinha S; Tin W
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2008;97(3):285-292
Cardiorespiratory development in extremely preterm infants: vulnerability to infection and persistence of events beyond term-equivalent age
Hofstetter AO; Legnevall L; Herlenius E; Katz-Salamon M
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2007;357(19):1893-1902
Long-term effects of caffeine therapy for apnea of prematurity
Schmidt B; Roberts RS; Davis P; Doyle LW; Barrington KJ; Ohlsson A; Solimano A; Tin W
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(23):9894-9899
The induced prostaglandin E₂ pathway is a key regulator of the respiratory response to infection and hypoxia in neonates
Hofstetter AO; Saha S; Siljehav V; Jakobsson P-J; Herlenius E
Article: EPILEPSIA. 2007;48(6):1138-1142
SCN2A mutations and benign familial neonatal-infantile seizures:: The phenotypic spectrum
Herlenius E; Heron SE; Grinton BE; Keay D; Scheffer IE; Mulley JC; Berkovic SF
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2006;354(20):2112-2121
Caffeine therapy for apnea of prematurity
Schmidt B; Roberts RS; Davis P; Doyle LW; Barrington KJ; Ohlsson A; Solimano A; Tin W
Article: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2005;146(2-3):135-146
Interleukin-1β depresses hypoxic gasping and autoresuscitation in neonatal DBA/11acJ mice
Hofstetter AO; Herlenius E
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2005;201(1):11-17
Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block
Salomonsson S; Sonesson SE; Ottosson L; Muhallab S; Olsson T; Sunnerhagen M; Kuchroo VK; Thorén P; Herlenius E; Wahren-Herlenius M
Article: JOURNAL OF PHYSIOLOGY. 2004;556(1):43-59
Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice
Nsegbe E; Wallen-Mackenzie Å; Dauger S; Roux JC; Shvarev Y; Lagercrantz H; Perlmann T; Herlenius E
Article: PEDIATRIC RESEARCH. 2003;54(3):326-331
IL-1β depresses respiration and anoxic survival via a prostaglandin-dependent pathway in neonatal rats
Olsson A; Kayhan G; Lagercrantz H; Herlenius E
Article: PEDIATRIC RESEARCH. 2002;51(1):4-12
Perinatal respiratory control and its modulation by adenosine and caffeine in the rat
Herlenius E; Ådén U; Tang LQ; Lagercrantz H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(16):9407-9412
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A₁ receptor
Johansson B; Halldner L; Dunwiddie TV; Masino SA; Poelchen W; Giménez-Llort L; Escorihuela RM; Fernández-Teruel A; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Betsholtz C; Herlenius E; Fredholm BB
Article: BRAIN RESEARCH. 2000;884(1-2):201-205
Effects of neuroactive substances on the morphine-induced respiratory depression; an in vitro study
Takita K; Herlenius E; Yamamoto Y; Lindahl SGE
Article: PEDIATRIC RESEARCH. 2000;48(2):177-183
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain
Ådén U; Herlenius E; Tang LQ; Fredholm BB
Article: JOURNAL OF PHYSIOLOGY. 1999;518(1):159-172
Adenosinergic modulation of respiratory neurones in the neonatal rat brainstem in vitro
Herlenius E; Lagercrantz H
Journal article: ANESTHESIOLOGY. 1998;89(Supplement):1358a
THE INTERACTION BETWEEN MORPHINE AND SOME NEUROACTIVE SUBSTANCES IN THE MEDULLARY RESPIRATION CENTER
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Journal article: PEDIATRIC RESEARCH. 1998;44(3):456
INFECTION AND INTERLEUKIN-1β VIA PROSTAGLANDIN E2 DEPRESSES RESPIRATION I: AN IN VITRO STUDY
Herlenius E; Lagercrantz H
Journal article: PEDIATRIC RESEARCH. 1998;44(3):456
INFECTION AND INTERLEUKIN-1β VIA PROSTAGLANDIN E2 DEPRESSES RESPIRATION II: AN IN VIVO STUDY
Herlenius E; Kayhan G; Lagercrantz H
Article: BRAIN RESEARCH. 1998;800(2):308-311
Age- and temperature-dependent effects of opioids on medulla oblongata respiratory activity: an in vitro study in newborn rat
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Journal article: ANESTHESIA AND ANALGESIA. 1998;86(2S):513s.-513S
THE INTERACTION BETWEEN MORPHINE AND ACETYLCHOLINE IN THE MEDULLARY RESPIRATION-RELATED STRUCTURES
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Article: BRAIN RESEARCH. 1997;778(1):233-241
Actions of opioids on respiratory activity via activation of brainstem μ-, δ- and κ-receptors;: an in vitro study
Takita K; Herlenius EAP; Lindahl SGE; Yamamoto Y
Article: PEDIATRIC RESEARCH. 1997;42(1):46-53
Adenosine modulates inspiratory neurons and the respiratory pattern in the brainstem of neonatal rats
Herlenius E; Lagercrantz H; Yamamoto Y
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Alla övriga publikationer

Preprint: HTTPS://BIOETHICSOPENRESEARCH.ORG/ARTICLES/2-3/V1. 2024
Systematic review of ethics and legislation of a Global Patient co-Owned Cloud (GPOC)
Herlenius E; Lidströmer N
Preprint: RESEARCH SQUARE. 2024
Review and Inquiries on Ethics, Policies and Regulations of a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Ashrafian H; Herlenius E
Preprint: RESEARCH SQUARE. 2024
Technical Sandbox for a Global Patient co-Owned Cloud (GPOC)
Davids J; ElSharkawy M; Ashrafian H; Herlenius E; Lidströmer N
Preprint: RESEARCH SQUARE PLATFORM LLC. 2024
Technical Sandbox for a Global Patient co-Owned Cloud (GPOC)
Davids J; ElSharkawy M; Ashrafian H; Herlenius E; Lidströmer N
Preprint: RESEARCH SQUARE. 2024
Review of the Ethics, Policies and Regulations of a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Ashrafian H; Herlenius E
Preprint: RESEARCH SQUARE. 2024
A Summit on a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Herlenius E; Ashrafian H
Book chapter: MACHINE LEARNING APPLICATIONS IN MEDICINE AND BIOLOGY. 2024;p. 115-149
Deep Recurrent Architectures for Neonatal Sepsis Detection from Vital Signs Data
Honoré A; Siren H; Vinuesa R; Chatterjee S; Herlenius E
Review: JOURNAL OF PHYSIOLOGY. 2023;601(21):4667-4689
Does fetal growth restriction induce neuropathology within the developing brainstem?
Ahmadzadeh E; Polglase GR; Stojanovska V; Herlenius E; Walker DW; Miller SL; Allison BJ
Preprint: RESEARCH SQUARE. 2023
Necessity of a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; Herlenius E; Ashrafian H
Preprint: RESEARCH SQUARE. 2023
Systematic Review and Meta-Analysis for a Global Patient co-Owned Cloud (GPOC)
Lidströmer N; Davids J; ElSharkawy M; ElSharkawy M; Herlenius E; Ashrafian H
Conference publication: 2022;00:1-6
An LSTM-based Recurrent Neural Network for Neonatal Sepsis Detection in Preterm Infants
Honoré A; Siren H; Vinuesa R; Chatterjee S; Herlenius E
Review: ISCIENCE. 2022;25(5):104295
The effect of the delta SARS-CoV-2 variant on maternal infection and pregnancy
Samara A; Khalil A; O'Brien P; Herlenius E
Preprint: INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS (IEEE). 2022
Classification and feature extraction for neonatal sepsis detection
Honoré A; Forsberg D; jost K; Adolphson K; Stålhammar A; Herlenius E; Chatterjee S
Preprint: INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS (IEEE). 2022
Classification and feature extraction for neonatal sepsis detection
Honoré A; Forsberg D; jost K; Adolphson K; Stålhammar A; Herlenius E; Chatterjee S
Editorial comment: CELL REPORTS MEDICINE. 2022;3(1):100490
Potential role of neurofilament in COVID-19 and preeclampsia Comment
Samara A; Herlenius E; Brien PO; Khalil A
Book chapter: ARTIFICIAL INTELLIGENCE IN MEDICINE. 2022;p. 1047-1056
AIM in Neonatal and Pediatric Intensive Care
Forsberg D; Honoré A; Jost K; Persad E; Coste K; Chatterjee S; Rautiainen S; Herlenius E
Book chapter: ARTIFICIAL INTELLIGENCE IN COVID-19. 2022;p. 257-277
AI and Dynamic Prediction of Deterioration in Covid-19
Danker C; Murzabekov M; Forsberg D; Lidströmer N; Honoré A; Rautiainen S; Herlenius E
Review: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(12):3201-3226
Neonatal sepsis prediction through clinical decision support algorithms: A systematic review
Persad E; Jost K; Honore A; Forsberg D; Coste K; Olsson H; Rautiainen S; Herlenius E
Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(9):2578-2580
Persistent symptoms in Swedish children after hospitalisation due to COVID-19
Sterky E; Olsson-Akefeldt S; Hertting O; Herlenius E; Alfven T; Ryd Rinder M; Rhedin S; Hildenwall H
Conference publication: THE FASEB JOURNAL. 2021;35
Immune Modulator Prostaglandin E2 exerts Biphasic Dose Response on the Pre-Botzinger Complex Respiratory Related Rhythm
Reising J; Phillips W; Herlenius E
Conference publication: PEDIATRIC RESEARCH. 2021;90(SUPPL 1):22
Body weight measurements support machine-learning algorithms in neonatal sepsis prediction
Stalhammar AM; Adolphson K; Honore A; Forsberg D; Herlenius E; Jost K
Conference publication: PEDIATRIC RESEARCH. 2021;90(SUPPL 1):22
Predicting acute adverse events in neonates using automated vital sign pattern analysis
Adolphson K; Honore A; Forsberg D; Stalhammar AM; Jost K; Herlenius E
Conference publication: PEDIATRIC RESEARCH. 2021;90(SUPPL 1):13-14
Medications and clinical decision support systems; how caffeine influences heart rate characteristics in preterm infants
Clareus A; Honore A; Koch G; Herlenius E; Jost K
Book chapter: ARTIFICIAL INTELLIGENCE IN MEDICINE. 2021;p. 1-10
AIM in Neonatal and Paediatric Intensive Care
Forsberg D; Honoré A; Jost K; Persad E; Coste K; Chatterjee S; Rautiainen S; Herlenius E
Letter: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2020;109(10):2152-2154
Paediatric COVID-19 admissions in a region with open schools during the two first months of the pandemic
Hildenwall H; Luthander J; Rhedin S; Hertting O; Olsson-Akefeldt S; Erik M; Alfven T; Herlenius E; Ryd Rinder M
Conference publication: 2020;00:1130-1134
Hidden Markov Models for Sepsis Detection in Preterm Infants
Honoré A; Liu D; Forsberg D; Coste K; Herlenius E; Chatterjee S; Skoglund M
Preprint: BIORXIV. 2019
Presynaptic dysfunction inCASK-related neurodevelopmental disorders
Becker M; Mastropasqua F; Reising JP; Maier S; Ho M-L; Rabkina I; Li D; Neufeld J; Ballenberger L; Myers L; Moritz V; Kele M; Wincent J; Willfors C; Sitnikov R; Herlenius E; Anderlid B-M; Falk A; Bölte S; Tammimies K
Preprint: ARXIV. 2019
Hidden Markov Models for sepsis detection in preterm infants
Honore A; Liu D; Forsberg D; Coste K; Herlenius E; Chatterjee S; Skoglund M
Published conference paper: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2019;265:3-8
Astrocyte networks modulate respiration - sniffing glue
Forsberg D; Herlenius E
Letter: JAMA PEDIATRICS. 2019;173(5):487-489
Self-reported Quality of Life at Middle School Age in Survivors of Very Preterm Birth: Results From the Caffeine for Apnea of Prematurity Trial
Schmidt B; Anderson PJ; Asztalos EV; Doyle L; Grunau RE; Moddemann D; Roberts RS
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27:1423
Resolving effects of CASK mutations in children with neurodevelopmental disorders
Becker M; Mastropasqua F; Reising JP; Rabkina I; Ballenberger L; Kele M; Willfors C; Herlenius E; Bolte S; Anderlid BM; Falk A; Tammimies K
Preprint: ARXIV. 2017
Large Neural Network Based Detection of Apnea, Bradycardia and Desaturation Events
Honoré A; Siljehav V; Chatterjee S; Herlenius E
Conference publication: CANCER RESEARCH. 2017;77:5832
Rho-associated kinase is a therapeutic target in neuroblastoma
Dyberg CH; Fransson S; Andonova T; Sveinbjornsson B; Lannerholm-Palm J; Forsberg D; Herlenius E; Martinsson T; Kogner P; Johnsen JI; Wickstrom M
Preprint: BIORXIV. 2017
Astrocytes release prostaglandin E2 to modify respiratory network activity
Forsberg D; Ringstedt T; Herlenius E
Review: CANCER CAUSES AND CONTROL. 2017;28(6):599-624
Maternal fetal loss history and increased acute leukemia subtype risk in subsequent offspring: a systematic review and meta-analysis
Karalexi MA; Dessypris N; Skalkidou A; Biniaris-Georgallis S-I; Kalogirou EI; Thomopoulos TP; Herlenius E; Spector LG; Loutradis D; Chrousos GP; Petridou ET
Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2017;106(2):191-193
Unexpected, unexplained and life-threatening events in infants are age-dependent descriptive syndromes with different risk and management
Herlenius E
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2015;67
Auxilin Is a Novel Susceptibility Gene for Congenital Heart Block Modulating Cardiac Function
Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Dzikaite-Ottosson V; Ding B; Strandberg L; Biavati L; Ramskold D; Forsberg D; Bergin L; Ruhrmann S; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Meeting abstract: PEDIATRIC RESEARCH. 2011;70:24
THE CAFFEINE FOR APNEA OF PREMATURITY (CAP) TRIAL: PRELIMINARY OUTCOMES AT 5 YEARS
Schmidt B; Anderson P; Doyle L; Dewey D; Grunau R; Asztalos E; Davis P; Tin W; Moddemann D; Solimano A; Ohlsson A; Barrington K; Roberts R
Review: RESPIRATORY PHYSIOLOGY AND NEUROBIOLOGY. 2011;178(3):449-457
An inflammatory pathway to apnea and autonomic dysregulation
Herlenius E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2011;73(4):349-350
Transfer of Ro52-p200 Monoclonals, but not Other Ro52-Specificities, Induce Congenital Heart Block (CHB) in a Rat Model
Dzikaite V; Ambrosi A; Park J; Ottosson L; Sonesson S-E; Kuchroo VK; Herlenius E; Wahren-Herlenius M
Published conference paper: EUROPEAN JOURNAL OF NEUROSCIENCE. 2010;31(12):2142-2155
Premature expression of KCC2 in embryonic mice perturbs neural development by an ion transport-independent mechanism
Horn Z; Ringstedt T; Blaesse P; Kaila K; Herlenius E
Book chapter: THE NEWBORN BRAIN. 2010;p. 99-120
Neurotransmitters and neuromodulators
Herlenius E; Lagercrantz H
Book chapter: THE NEWBORN BRAIN. 2010;p. 71-84
The neonatal synaptic big bang
Bourgeois J-P
Conference publication: CELL TRANSPLANTATION. 2010;19(3):344
Communication Via Gap Junctions Underlies Early Functional and Beneficial Interactions Between Grafted Neural Stem Cells and the Host
Jaderstad J; Jaderstad LM; Li J; Chintawar S; Salto C; Pandolfo M; Ourednik V; Teng YD; Sidman RL; Arenas E; Snyder EY; Herlenius E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2010;72(3):274
Ro52 Autoantibodies Specific for Amino Acid 200-239 Mediate Calcium Dysregulation in Cardiomyocytes
Herlenius E; Park J; Ambrosi A; Dzikate V; Strandberg L; Kuchroo V; Wahren-Herlenius M
Conference publication: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2010;99:19
INFECTIOUS DISEASES AND SIDS: AN INFLAMMATORY PATHWAY TO APNEA AND AUTONOMIC DYSREGULATION
Herlenius E
Conference publication: EPILEPSIA. 2007;48:127
Benign familial neonatal-infantile seizures: The mutational and phenotypic spectrum
Heron S; Grinton B; Herlenius E; Keay D; Kron K; Mulley J; Scheffer I; Berkovic S
Meeting abstract: EXPERIMENTAL NEUROLOGY. 2006;198(2):572
Communication via gap junctions underlies early functional interactions between grafted neural stem cells and the host
Jäderstad J; Danielsson LM; Ourednik V; Snyder EY; Herlenius E
Conference publication: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2006;79(1-2):156
MPGES-1 derived PGE2 regulates fever and mediates IL-1beta induced respiratory depression in DBA/11acj mice through central mechanisms
Saha S; Engström L; Mackerlova L; Hofstetter AO; Hebert H; Herlenius E; Blomqvist A; Jakobsson PJ
Review: EXPERIMENTAL NEUROLOGY. 2004;190:S8-21
Development of neurotransmitter systems during critical periods
Herlenius E; Lagercrantz H
Meeting abstract: PEDIATRIC RESEARCH. 2004;56(3):482
Reduced expression of microsomal prostaglandin synthase 1 attenuates ventilatory effects of interleukin-1A in neonatal DBA/1LacJ mice
Hofstetter AO; Saha S; Lagercrantz H; Jakobsson PJ; Herlenius E
Conference publication: PEDIATRIC RESEARCH. 2004;55(4):511A
Interieukin-1β depresses respiration and anoxic survival in newborn mice
Hofstetter AO; Saba S; Lagercrantz H; Jakobsson PJ; Herlenius E
Published conference paper: DRUG DEVELOPMENT RESEARCH. 2003;58(4):350-353
Consequences of eliminating adenosine A₁ receptors in mice
Fredholm BB; Halldner L; Johansson C; Schulte G; Lövdahl C; Thorén P; Dunwiddie TV; Masino SA; Poelchen W; Diao LH; Illes P; Zahniser NR; Valen G; Tokuno S; Sommerschild H; Giménez-Llort L; Fernández-Teruel A; Escorihuela RM; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Herlenius E; Pekny S; Gebré-Medhin S; Brown R; Ollerstam A; Persson AEG; Skott O; Johansson B
Conference publication: PEDIATRIC RESEARCH. 2003;54(4):594
Integration of exogenous stem cells into striatal organotypic cultures
Jäderstad J; Ourednik V; Snyder EY; Herlenius E
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2003;48(9):S64
Ro52 monoclonal antibodies bind the cell surface of cardiomyocytes
Salomonsson S; Ottosson L; RAats J; Herlenius E; Wahren-Herlenius M
Conference publication: EXPERIMENTAL NEUROLOGY. 2002;175(2):418
Tracing of multisynaptic fiber tracts originating from grafted neural stem cells - A study using plant lectins.
Ourednik V; Ourednik J; Herlenius E; Zou Z; Snyder EY
Review: EARLY HUMAN DEVELOPMENT. 2001;65(1):21-37
Neurotransmitters and neuromodulators during early human development
Herlenius E; Lagercrantz H
Conference publication: JOURNAL OF PHYSIOLOGY. 2001;533:10S
Respiratory rhythm generation in the perinatal period and its modulation by GABA and adenosine
Herlenius E
Conference publication: PEDIATRIC RESEARCH. 2000;47(4):70A
Fetal and neonatal respiratory activity and its modulation by adenosine and caffeine
Herlenius E; Aden U; Tang LO; Lagercrantz H
Thesis / dissertation: 1998
Respiratory activity in medulla oblongata and its modulation by adenosine and opioids
Herlenius, Eric
Conference publication: ANESTHESIOLOGY. 1998;89(3A):U1037
The interaction between morphine and some neuroactive substances in the medullary respiration center:: An in vitro study in the newborn rat.
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Conference publication: ANESTHESIA AND ANALGESIA. 1998;86(2S)
The interaction between morphine and acetylcholine in the medullary respiration-related structures:: An in vitro study in the newborn rat.
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Meeting abstract: ANESTHESIOLOGY. 1997;87(3):A1074
Mu-1 opioid receptor in the medulla oblongata is involved in the opioid-induced respiratory depression: An in vitro study in the newborn rat.
Takita K; Herlenius E; Lindahl SGE; Yamamoto Y
Preprint: SSRN ELECTRONIC JOURNAL.
Astrocytic Calcium Signaling Toolkit (astroCAST): Efficient Analysis of Dynamic Astrocytic Calcium Events
Reising J; Sanchez ACG; Samara A; Herlenius E
Visa fler

Forskningsbidrag

Genes(is) of Inspiration - Screen, detect and protect against inflammation induced life-threatening events.
Swedish Research Council
1 January 2024 - 31 December 2027
Probiotic supplementation in extremely preterm infants in Scandinavia: A double-blinded randomized controlled multicenter trial to reduce the risk of necrotizing enterocolitis and mortality
Swedish Research Council
1 January 2023 - 31 December 2026
INSPIRATION AND LIFE-THREATENING EVENTS AFTER BIRTH – Pathophysiological mechanisms
Swedish Research Council
1 January 2020 - 31 December 2023
APNEA and INSPIRATIONSCREEN, DETECT AND PROTECT AGAINST INFLAMMATION INDUCED LIFE-THREATENING EVENTS
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2021
NEWS - Newborn Early Warning Signs
Swiss National Science Foundation
1 June 2017 - 31 July 2017
INSPIRATION AND LIFE-THREATENING EVENTS AFTER BIRTH – Pathophysiological mechanisms
Swedish Research Council
1 January 2017 - 31 December 2019
Novel methods to SCREEN, DETECT and PROTECT against life threatening respiratory dysfunction
VINNOVA
6 December 2010 - 30 November 2014
ACTIVITY DEPENDENT DEVELOPMENT OF AUTONOMIC CONTROL APNEA INFLAMMATION and INSPIRATION
Swedish Research Council
1 January 2010 - 31 December 2012
Activity dependent development of autonomic control
Swedish Research Council
1 January 2009 - 31 December 2014
Activity dependent development of autonomic control
Swedish Research Council
1 January 2009 - 31 December 2014
Activity dependent development of autonomic control
Swedish Research Council
1 January 2009 - 31 December 2014

Anställningar

Professor/Överläkare, Kvinnors och barns hälsa, Karolinska Institutet, 2013-

Examina och utbildning

Docent, Experimentell pediatrik, Karolinska institutet, 2008
MEDICINE DOKTORSEXAMEN, Institutionen för kvinnors och barns hälsa, Karolinska Institutet, 1998
Läkarexamen, Karolinska Institutet, 1994

Uppdrag

Avdelningschef, Klinisk pediatrik, Institutionen för kvinnors och barns hälsa, Karolinska Institutet, 2024-

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