Erdinc Sezgin

Om mig
Publikationer
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CV
Populärvetenskap och samverkan

Om mig

Please visit the English version of the website [1] for details.
[1] https://staff.ki.se/people/erdsez?_ga=2.50627369.1066920700.1583140098-746479776.1550748706

Artiklar

Article: NATURE BIOMEDICAL ENGINEERING. 2024;8(11):1453-1468
Antibody-displaying extracellular vesicles for targeted cancer therapy
Wiklander OPB; Mamand DR; Mohammad DK; Zheng W; Jawad Wiklander R; Sych T; Zickler AM; Liang X; Sharma H; Lavado A; Bost J; Roudi S; Corso G; Lennaard AJ; Abedi-Valugerdi M; Maeger I; Alici E; Sezgin E; Nordin JZ; Gupta D; Goergens A; EL Andaloussi S
Article: MOLECULAR THERAPY. 2024;32(9):3012-3024
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski B; Christ W; Corman A; Haraldsson M; Barz M; Lidemalm L; Haggblad M; Ilmain J; Wright SC; Murga M; Schlegel J; Jarvius M; Lapins M; Sezgin E; Bhabha G; Lauschke VM; Carreras-Puigvert J; Lafarga M; Klingstrom J; Huhn D; Fernandez-Capetillo O
Article: BIOPHYSICAL JOURNAL. 2024;123(16):2484-2495
Quantification of membrane fluidity in bacteria using TIR-FCS
Barbotin A; Billaudeau C; Sezgin E; Carballido-Lopez R
Article: NATURE BIOTECHNOLOGY. 2024;42(4):587-590
High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler
Sych T; Schlegel J; Barriga HMG; Ojansivu M; Hanke L; Weber F; Bostancioglu RB; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; El Andaloussi S; Fuerth D; Stevens MM; Sezgin E
Article: MOLECULAR SYSTEMS BIOLOGY. 2024;20(4):374-402
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis
Sommerauer C; Gallardo-Dodd CJ; Savva C; Hases L; Birgersson M; Indukuri R; Shen JX; Carravilla P; Geng K; Sondergaard JN; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-Andre M; Petersson C; Hagstrom H; Lauschke VM; Archer A; Williams C; Kutter C
Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2024;128(9):2154-2167
Quantifying Fluorescence Lifetime Responsiveness of Environment-Sensitive Probes for Membrane Fluidity Measurements
Ragaller F; Sjule E; Urem YB; Schlegel J; El R; Urbancic D; Urbancic I; Blom H; Sezgin E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2024;300(2):105649
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors
Menon I; Sych T; Son Y; Morizumi T; Lee J; Ernst OP; Khelashvili G; Sezgin E; Levitz J; Menon AK
Article: NATURE COMMUNICATIONS. 2024;15(1):541
Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis
Drexhage LZ; Zhang S; Dupont M; Ragaller F; Sjule E; Cabezas-Caballero J; Deimel LP; Robertson H; Russell RA; Dushek O; Sezgin E; Karaji N; Sattentau QJ
Article: ACS APPLIED BIO MATERIALS. 2023;6(12):5746-5758
Protein-Decorated Microbubbles for Ultrasound-Mediated Cell Surface Manipulation
Brans VA; Gray MD; Sezgin E; Stride EPJ
Journal article: BIOCONJUGATE CHEMISTRY. 2023;34(10):1923
Correction to Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells
Sternstein C; Bohm T-M; Fink J; Meyr J; Ludemann M; Krug M; Kriukov K; Sezgin E; Ebert R; Seibel J
Article: BIOCONJUGATE CHEMISTRY. 2023;34(7):1221-1233
Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells
Sternstein C; Boehm T-M; Fink J; Meyr J; Luedemann M; Krug M; Kriukov K; Gurdap CO; Sezgin E; Ebert R; Seibel J
Article: NANO LETTERS. 2023;23(9):3701-3707
A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens
Schlegel J; Porebski B; Andronico L; Hanke L; Edwards S; Brismar H; Murrell B; McInerney GM; Fernandez-Capetillo O; Sezgin E
Article: NATURE METABOLISM. 2023;5(3):495-515
PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing
Cikes D; Elsayad K; Sezgin E; Koitai E; Ferenc T; Orthofer M; Yarwood R; Heinz LX; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; al-Murshedi F; Abot A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov A; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain JS; Bakovic M; Banka S; Penninger JM
Article: NATURE COMMUNICATIONS. 2022;13(1):7868
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease
Leng H; Zhang H; Li L; Zhang S; Wang Y; Chavda SJ; Galas-Filipowicz D; Lou H; Ersek A; Morris EV; Sezgin E; Lee Y-H; Li Y; Lechuga-Vieco AV; Tian M; Mi J-Q; Yong K; Zhong Q; Edwards CM; Simon AK; Horwood NJ
Article: BIOPHYSICAL JOURNAL. 2022;121(20):3826-3836
Influence of the extracellular domain size on the dynamic behavior of membrane proteins
Gurdap CO; Wedemann L; Sych T; Sezgin E
Article: OPEN BIOLOGY. 2022;12(9):220175
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Abhinav; Danylchuk DII; Hof M; Klymchenko A; Amaro M; Vattulainen I; Sezgin E
Article: NATURE COMMUNICATIONS. 2022;13(1):3460
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles
Cespedes PF; Jainarayanan A; Fernandez-Messina L; Valvo S; Saliba DG; Kurz E; Kvalvaag A; Chen L; Ganskow C; Colin-York H; Fritzsche M; Peng Y; Dong T; Johnson E; Siller-Farfan JA; Dushek O; Sezgin E; Peacock B; Law A; Aubert D; Engledow S; Attar M; Hester S; Fischer R; Sanchez-Madrid F; Dustin ML
Article: BIOPHYSICAL REPORTS. 2022;2(2):None-100055
Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5
Galiani S; Reglinski K; Carravilla P; Barbotin A; Urbancic I; Ott J; Sehr J; Sezgin E; Schneider F; Waithe D; Hublitz P; Schliebs W; Erdmann R; Eggeling C
Journal article: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2022;151(4):a154
Exploration of ultrasound-mediated microbubble-cell membrane interactions using novel protein-loaded microbubbles and their role in immunomodulation
Brans VA; Gray M; Sezgin E; Stride EP
Article: BIOCHIMICA ET BIOPHYSICA ACTA - BIOMEMBRANES. 2022;1864(4):183857
Giant plasma membrane vesicles to study plasma membrane structure and dynamics
Sezgin E
Article: NATURE COMMUNICATIONS. 2022;13(1):155
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Hanke L; Das H; Sheward DJ; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith NL; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen GK; Coquet JM; Hallberg BM; Murrell B; McInerney GM
Article: BIOPHYSICAL REPORTS. 2021;1(2):None-100023
Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes
Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Article: SCIENCE ADVANCES. 2021;7(49):eabj9247
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency
Rota IA; Handel AE; Maio S; Klein F; Dhalla F; Deadman ME; Cheuk S; Newman JA; Michaels YS; Zuklys S; Prevot N; Hublitz P; Charles PD; Gkazi AS; Adamopoulou E; Qasim W; Davies EG; Hanson I; Pagnamenta AT; Camps C; Dreau HM; White A; James K; Fischer R; Gileadi O; Taylor JC; Fulga T; Lagerholm BC; Anderson G; Sezgin E; Hollaender GA
Article: CELL REPORTS. 2021;37(5):109911
Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis
Matias MI; Yong CS; Foroushani A; Goldsmith C; Mongellaz C; Sezgin E; Levental KR; Talebi A; Perrault J; Riviere A; Dehairs J; Delos O; Bertand-Michel J; Portais J-C; Wong M; Marie JC; Kelekar A; Kinet S; Zimmermann VS; Levental I; Yvan-Charvet L; Swinnen JV; Muljo SA; Hernandez-Vargas H; Tardito S; Taylor N; Dardalhon V
Article: FEBS LETTERS. 2021;595(16):2127-2146
Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbancic I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; O'Brien-Ball C; Vuong MT; Ashman N; Sezgin E; Eggeling C
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):681
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
Oftedal BE; Maio S; Handel AE; White MPJ; Howie D; Davis S; Prevot N; Rota IA; Deadman ME; Kessler BM; Fischer R; Trede NS; Sezgin E; Maizels RM; Hollander GA
Article: ISCIENCE. 2021;24(1):101891
Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteins
Schneider F; Sych T; Eggeling C; Sezgin E
Article: BIOMOLECULES. 2021;11(1):100
Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis
Ozalp O; Cark O; Azbazdar Y; Haykir B; Cucun G; Kucukaylak I; Alkan-Yesilyurt G; Sezgin E; Ozhan G
Article: BIOCHEMISTRY. 2020;59(45):4421-4428
Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors
Plochberger B; Sych T; Weber F; Novacek J; Axmann M; Stangl H; Sezgin E
Article: ANALYTICAL CHEMISTRY. 2020;92(21):14798-14805
Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes
Danylchuk DI; Sezgin E; Chabert P; Klymchenko AS
Journal article: CHEMICAL SCIENCE. 2020;11(33):8955-8960
Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyad
Frawley AT; Wycisk V; Xiong Y; Galiani S; Sezgin E; Urbancic I; Jentzsch AV; Leslie KG; Eggeling C; Anderson HL
Article: PLOS PATHOGENS. 2020;16(7):e1008656
Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation
Sieben C; Sezgin E; Eggeling C; Manley S
Article: NATURE CHEMICAL BIOLOGY. 2020;16(6):644-652
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
Lorent JH; Levental KR; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova MD; Lyman E; Levental I
Journal article: NATURE CHEMICAL BIOLOGY. 2020;16(6):710
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape (vol 45, pg 513, 2020)
Lorent JH; Levental KR; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova M; Lyman E; Levental I
Article: BIOPHYSICAL JOURNAL. 2020;118(10):2448-2457
z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics
Barbotin A; Urbancic I; Galiani S; Eggeling C; Booth M; Sezgin E
Article: JOURNAL PHYSICS D: APPLIED PHYSICS. 2020;53(16):164003
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy
Schneider F; Hernandez-Varas P; Lagerholm BC; Shrestha D; Sezgin E; Roberti MJ; Ossato G; Hecht F; Eggeling C; Urbancic I
Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2020;124(8):1487-1494
Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes
Beckers D; Urbancic D; Sezgin E
Article: MEMBRANES. 2020;10(2):E30-30
Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure
Sezgin E; Carugo D; Levental I; Stride E; Eggeling C
Article: NATURE COMMUNICATIONS. 2020;11(1):756
Regulation of lipid saturation without sensing membrane fluidity
Ballweg S; Sezgin E; Doktorova M; Covino R; Reinhard J; Wunnicke D; Haenelt I; Levental I; Hummer G; Ernst R
Journal article: BIOPHYSICAL JOURNAL. 2020;118(3):389a
Simulations of an Asymmetric Mammalian Lipidome
Doktorova M; Levental KR; Sezgin E; Levental I; Lyman ER
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:590121
Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition
Luhr JJ; Alex N; Amon L; Krater M; Kubankova M; Sezgin E; Lehmann CHK; Heger L; Heidkamp GF; Smith A-S; Zaburdaev V; Bockmann RA; Levental I; Dustin ML; Eggeling C; Guck J; Dudziak D
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:574363
Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae
Reglinski K; Steinfort-Effelsberg L; Sezgin E; Klose C; Platta HW; Girzalsky W; Eggeling C; Erdmann R
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:608484
Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse
Felce JH; Parolini L; Sezgin E; Cespedes PF; Korobchevskaya K; Jones M; Peng Y; Dong T; Fritzsche M; Aarts D; Frater J; Dustin ML
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(34):12599-12609
Nanoscale dynamics of cholesterol in the cell membrane
Pinkwart K; Schneider F; Lukoseviciute M; Sauka-Spengler T; Lyman E; Eggeling C; Sezgin E
Article: NANO LETTERS. 2019;19(4):2562-2567
Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes
Axmann M; Sezgin E; Karner A; Novacek J; Brodesser MD; Roehrl C; Preiner J; Stangl H; Plochberger B
Article: NATURE PROTOCOLS. 2019;14(4):1054-1083
Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS
Sezgin E; Schneider F; Galiani S; Urbancic I; Waithe D; Lagerholm BC; Eggeling C
Journal article: BIOPHYSICAL JOURNAL. 2019;116(3):327a-328a
Measuring Hindered Diffusion Dynamics in Live Cell Plasma Membranes with Confocal and Super-Resolution Imaging
Schneider F; Sezgin E; Waithe D; Fritzsche M; Eggeling C
Article: COMMUNICATIONS BIOLOGY. 2019;2:337
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density
Steinkuehler J; Sezgin E; Urbancic I; Eggeling C; Dimova R
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2019;7:281
More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.
Azbazdar Y; Ozalp O; Sezgin E; Veerapathiran S; Duncan AL; Sansom MSP; Eggeling C; Wohland T; Karaca E; Ozhan G
Article: SCIENCE SIGNALING. 2018;11(561):eaat0756
CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity
Felce JH; Sezgin E; Wane M; Brouwer H; Dustin ML; Eggeling C; Davis SJ
Article: BIOCHIMICA ET BIOPHYSICA ACTA - BIOMEMBRANES. 2018;1860(11):2436-2445
How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative
Mobarak E; Javanainen M; Kulig W; Honigmann A; Sezgin E; Aho N; Eggeling C; Rog T; Vattulainen I
Article: JOURNAL OF CELL SCIENCE. 2018;132(4):jcs219709
Reconstitution of immune cell interactions in free-standing membranes
Jenkins E; Santos AM; O'Brien-Ball C; Felce JH; Wilcock MJ; Hatherley D; Dustin ML; Davis SJ; Eggeling C; Sezgin E
Article: ACS NANO. 2018;12(8):8540-8546
Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion
Schneider F; Waithe D; Lagerholm BC; Shrestha D; Sezgin E; Eggeling C; Fritzsche M
Journal article: ATHEROSCLEROSIS. 2018;275:e23
INTERACTION OF LIPOPROTEIN PARTICLES WITH LIPID BILAYER-MEMBRANES
Plochberger B; Roehrl C; Preiner J; Karner A; Axmann M; Novacek J; Sezgin E; Eggeling C; Hinterndorfer P; Schuetz GJ; Stangl H
Article: NANO LETTERS. 2018;18(7):4233-4240
Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging
Schneider F; Waithe D; Galiani S; de la Serna JB; Sezgin E; Eggeling C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(7):1120-1136
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling
Hertzog J; Dias AGJ; Rigby RE; Donald CL; Mayer A; Sezgin E; Song C; Jin B; Hublitz P; Eggeling C; Kohl A; Rehwinkel J
Article: JOURNAL PHYSICS D: APPLIED PHYSICS. 2018;51(23):235401
Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy
Reina F; Galiani S; Shrestha D; Sezgin E; de Wit G; Cole D; Lagerholm BC; Kukura P; Eggeling C
Journal article: CHEMICAL SCIENCE. 2018;9(15):3892
Spironaphthoxazine switchable dyes for biological imaging (vol 9, pg 3029, 2018)
Xiong Y; Jentzsch AV; Osterrieth JWM; Sezgin E; Sazanovich IV; Reglinski K; Galiani S; Parker AW; Eggeling C; Anderson HL
Article: CHEMICAL SCIENCE. 2018;9(11):3029-3040
Spironaphthoxazine switchable dyes for biological imaging
Xiong Y; Jentzsch AV; Osterrieth JWM; Sezgin E; Sazanovich IV; Reglinski K; Galiani S; Parker AW; Eggeling C; Anderson HL
Article: SCIENTIFIC REPORTS. 2017;7(1):15886
HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study
Plochberger B; Roehrl C; Preiner J; Rankl C; Brameshuber M; Madl J; Bittman R; Ros R; Sezgin E; Eggeling C; Hinterdorfer P; Stangl H; Schuetz GJ
Article: BIOPHYSICAL JOURNAL. 2017;113(6):1321-1330
Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy
Sezgin E; Schneider F; Zilles V; Urbancic I; Garcia E; Waithe D; Klymchenko AS; Eggeling C
Article: THE FEBS JOURNAL. 2017;284(15):2513-2526
Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments
Sezgin E; Azbazdar Y; Ng XW; Teh C; Simons K; Weidinger G; Wohland T; Eggeling C; Ozhan G
Article: NATURE COMMUNICATIONS. 2017;8:15940
A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
Diepold A; Sezgin E; Huseyin M; Mortimer T; Eggeling C; Armitage JP
Article: MOLECULAR BIOLOGY OF THE CELL. 2017;28(11):1507-1518
Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS
Schneider F; Waithe D; Clausen MP; Galiani S; Koller T; Ozhan G; Eggeling C; Sezgin E
Article: BMC BIOINFORMATICS. 2017;18(1):254
Spectral imaging toolbox: segmentation, hyperstack reconstruction, and batch processing of spectral images for the determination of cell and model membrane lipid order
Aron M; Browning R; Carugo D; Sezgin E; de la Serna JB; Eggeling C; Stride E
Article: JOURNAL PHYSICS D: APPLIED PHYSICS. 2017;50(13):134004
Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane
Amaro M; Reina F; Hof M; Eggeling C; Sezgin E
Article: ACS OMEGA. 2017;2(3):994-1002
Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes
Pereno V; Carugo D; Bau L; Sezgin E; de la Serna JB; Eggeling C; Stride E
Article: NATURE COMMUNICATIONS. 2017;8:14347
Self-organizing actin patterns shape membrane architecture but not cell mechanics
Fritzsche M; Li D; Colin-York H; Chang VT; Moeendarbary E; Felce JH; Sezgin E; Charras G; Betzig E; Eggeling C
Journal article: MATTERS. 2017
Rituximab capping triggers intracellular reorganization of B cells
Koller T; Blok S; Santos AM; Oszmiana A; Davis D; Sezgin E; Eggeling C
Article: BIOMATERIALS. 2017;113:105-117
Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles
Carugo D; Aron M; Sezgin E; de la Serna JB; Kuirnova MK; Eggeling C; Stride E
Article: FRONTIERS IN PHYSIOLOGY. 2017;8:252
Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin
Rissanen S; Grzybek M; Orlowski A; Rog T; Cramariuc O; Levental I; Eggeling C; Sezgin E; Vattulainen I
Article: ORGANIC LETTERS. 2016;18(15):3666-3669
Photoswitchable Spiropyran Dyads for Biological Imaging
Xiong Y; Rivera-Fuentes P; Sezgin E; Jentzsch AV; Eggeling C; Anderson HL
Article: BIOPHYSICAL JOURNAL. 2016;110(11):2441-2450
Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy
Steshenko O; Andrade DM; Honigmann A; Mueller V; Schneider F; Sezgin E; Hell SW; Simons M; Eggeling C
Article: BIOINFORMATICS. 2016;32(6):958-960
FoCuS-point: software for STED fluorescence correlation and time-gated single photon counting
Waithe D; Clausen MP; Sezgin E; Eggeling C
Article: JOURNAL OF LIPID RESEARCH. 2016;57(2):299-309
A comparative study on fluorescent cholesterol analogs as versatile cellular reporters
Sezgin E; Can FB; Schneider F; Clausen MP; Galiani S; Stanly TA; Waithe D; Colaco A; Honigmann A; Wustner D; Platt F; Eggeling C
Article: METHODS. 2015;88:67-75
A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics
Clausen MP; Sezgin E; de la Serna JB; Waithe D; Lagerholm BC; Eggeling C
Article: NANO LETTERS. 2015;15(9):5912-5918
STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics
Vicidomini G; Ta H; Honigmann A; Mueller V; Clausen MP; Waithe D; Galiani S; Sezgin E; Diaspro A; Hell SW; Eggeling C
Journal article: CELL. 2015;161(6):1472
Membrane Nanoclusters-Tails of the Unexpected (vol 161, pg 433, 2015)
Sezgin E; Davis SJ; Eggeling C
Journal article: CHEMPHYSCHEM. 2015;16(7):1560
Back Cover: Spectral Imaging to Measure Heterogeneity in Membrane Lipid Packing (ChemPhysChem 7/2015)
Sezgin E; Waithe D; de la Serna JB; Eggeling C
Article: CHEMPHYSCHEM. 2015;16(7):1387-1394
Spectral Imaging to Measure Heterogeneity in Membrane Lipid Packing
Sezgin E; Waithe D; de la Serna JB; Eggeling C
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1853(4):802-809
Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains
Beck-Garcia K; Beck-Garcia E; Bohler S; Zorzin C; Sezgin E; Levental I; Alarcon B; Schamel WWA
Article: PLOS ONE. 2015;10(4):e0123930
Adaptive Lipid Packing and Bioactivity in Membrane Domains
Sezgin E; Gutmann T; Buhl T; Dirkx R; Grzybek M; Coskun U; Solimena M; Simons K; Levental I; Schwille P
Article: NATURE COMMUNICATIONS. 2014;5:5412
Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells
Honigmann A; Mueller V; Ta H; Schoenle A; Sezgin E; Hell SW; Eggeling C
Article: LANGMUIR. 2014;30(27):8160-8166
Measuring Lipid Packing of Model and Cellular Membranes with Environment Sensitive Probes
Sezgin E; Sadowski T; Simons K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(50):35660-35670
Bile Acids Modulate Signaling by Functional Perturbation of Plasma Membrane Domains
Zhou Y; Maxwell KN; Sezgin E; Lu M; Liang H; Hancock JF; Dial EJ; Lichtenberger LM; Levental I
Article: DEVELOPMENTAL CELL. 2013;26(4):331-345
Lypd6 Enhances Wnt/β-Catenin Signaling by Promoting Lrp6 Phosphorylation in Raft Plasma Membrane Domains
Oezhan G; Sezgin E; Wehner D; Pfister AS; Kuehl SJ; Kagermeier-Schenk B; Kuehl M; Schwille P; Weidinger G
Journal article: CHEMBIOCHEM. 2013;14(6):657
Cover Picture: Photoconversion of Bodipy‐Labeled Lipid Analogues (ChemBioChem 6/2013)
Sezgin E; Chwastek G; Aydogan G; Levental I; Simons K; Schwille P
Article: CHEMBIOCHEM. 2013;14(6):695-698
Photoconversion of Bodipy-Labeled Lipid Analogues
Sezgin E; Chwastek G; Aydogan G; Levental I; Simons K; Schwille P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(35):14236-14240
Functional convergence of hopanoids and sterols in membrane ordering
Saenz JP; Sezgin E; Schwille P; Simons K
Article: MOLECULAR MEMBRANE BIOLOGY. 2012;29(5):144-154
Model membrane platforms to study protein-membrane interactions
Sezgin E; Schwille P
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1818(7):1777-1784
Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes
Sezgin E; Levental I; Grzybek M; Schwarzmann G; Mueller V; Honigmann A; Belov VN; Eggeling C; Coskun U; Simons K; Schwille P
Article: NATURE PROTOCOLS. 2012;7(6):1042-1051
Elucidating membrane structure and protein behavior using giant plasma membrane vesicles
Sezgin E; Kaiser H-J; Baumgart T; Schwille P; Simons K; Levental I
Article: ACS NANO. 2012;6(3):2150-2156
Penetration of Amphiphilic Quantum Dots through Model and Cellular Plasma Membranes
Dubavik A; Sezgin E; Lesnyak V; Gaponik N; Schwille P; Eychmueller A
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2011;3(11):a009803
Fluorescence Techniques to Study Lipid Dynamics
Sezgin E; Schwille P
Article: COLLOIDS AND SURFACES B: BIOINTERFACES. 2009;71(2):315-318
Interaction of gold nanoparticles with mitochondria
Karatas OF; Sezgin E; Aydin O; Culha M
Journal article:
Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation
Matias MI; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Perrault J; Rivière A; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
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Preprint: BIORXIV. 2024
High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states
Andronico L; Jiang Y; Carannante V; Iskrak S; Sandoz P; Mikes J; Klymchenko A; Buggert M; Österborg A; Önfelt B; Brodin P; Sezgin E
Preprint: BIORXIV. 2024;BIORXIV
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.
Menon I; Sych T; Son Y; Morizumi T; Lee J; Ernst OP; Khelashvili G; Sezgin E; Levitz J; Menon AK
Preprint: BIORXIV. 2023
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski B; Christ W; Corman A; Haraldsson M; Barz M; Lidemalm L; Häggblad M; Ilmain J; Wright S; Murga M; Shlegel J; Sezgin E; Bhabha G; Lauschke V; Lafarga M; Klingström J; Huhn D; Fernandez-Capetillo O
Preprint: BIORXIV. 2023
Quantifying fluorescence lifetime responsiveness of environment sensitive probes for membrane fluidity measurements
Ragaller F; Sjule E; Urem YB; Schlegel J; El R; Urbancic D; Urbancic I; Blom H; Sezgin E
Preprint: BIORXIV. 2023
Quantification of membrane fluidity in bacteria using TIR-FCS
Barbotin A; Billaudeau C; Sezgin E; Carballido-López R
Preprint: BIORXIV. 2023
Estrogen receptor activation remodelsTEAD1gene expression to alleviate nonalcoholic fatty liver disease
Sommerauer C; Gallardo-Dodd C; Savva C; Hases L; Birgersson M; Indukuri R; Shen J; Carravilla P; Geng K; Nørskov Søndergaard J; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-André M; Petersson C; Hagström H; Lauschke V; Archer A; Williams C; Kutter C
Preprint: BIORXIV. 2023
Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis
Drexhage LZ; Zhang S; DuPont M; Ragaller F; Sjule E; Caballero JC; Deimel L; Robertson H; Russell RA; Dushek O; Sezgin E; Karaji N; Sattentau QJ
Preprint: BIORXIV. 2023
Cell membranes sustain phospholipid imbalance via cholesterol asymmetry
Doktorova M; Symons J; Zhang X; Wang H-Y; Schlegel J; Lorent J; Heberle F; Sezgin E; Lyman E; Levental K; Levental I
Preprint: RES SQ. 2023;RES SQ
Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Terenius L; Oasa S; Sezgin E; Ma Y; Horne D; Radmiković M; Jovanović-Talisman T; Martin-Fardon R; Vukojevic V
Preprint: BIORXIV. 2023
Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response
Deimel LP; Xue X; Khan A; Moynie L; Buchanan CJ; Sun G; McBride R; Schuster H; Gauthier C; Saliba R; Leonavicus K; Minall L; Bort G; Russell RA; Sezgin E; Paulson JC; Anthony DC; Baldwin AJ; Naismith J; Schiffner T; Davis BG; Sattentau QJ
Editorial comment: BIOPHYSICAL JOURNAL. 2023;122(11):E1-E4
Membranes in focus
Sezgin E; Levental I
Other: NATURE CHEMICAL BIOLOGY. 2023;19(6):669-670
Do lipids tune B cell signaling?
Urbancic I; Eggeling C; Sezgin E
Corrigendum: NATURE METABOLISM. 2023;5(4):711
PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing (vol 5, pg 495, 2023)
Cikes D; Elsayad K; Sezgin E; Koitai E; Torma F; Orthofer M; Yarwood R; Heinz LX; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; Al-Murshedi F; Abot A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov AV; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain JS; Bakovic M; Banka S; Penninger JM
Editorial comment: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2023;24(4):237
Voices of the new generation: normalizing career choices outside academia
Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):222A
HDL-membrane-interactions are highly influenced by the target membrane-lipid composition
Weber F; Stangl H; Synch T; Plochberger B; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):224A
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Abhinav A; Danylchuk DI; Hof M; Klymchenko AS; Amaro M; Vattulainen I; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):362A
Measuring the fluidity of the membrane of Bacillus subtilis using TIR-FCS
Barbotin AGL; Lablaine A; Billaudeau C; Sezgin E; Carballido-Lopez R
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S122
Revealing the mechanism of the lipid storage disorder Niemann-Pick C by combining multi-omics and biophysical imaging
Carravilla P; Ceplaite U; Sommerauer C; Veiga RG; Sezgin E; Kutter C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S83
High-throughput biophysical mapping for diagnostic
Gurdap C; Andronico L; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S158
A guideline for quantitative characterization and application of environment-sensitive probes
Urem YB; Sjule E; Ragaller F; Schlegel J; Andronico L; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S165
HDL-MEMBRANE-INTERACTIONS ARE HIGHLY INFLUENCED BY THE TARGET MEMBRANE-LIPID COMPOSITION
Weber F; Stangl H; Synch T; Plochberger B; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S64
Single particle profiler for measuring content and properties of nano-sized bioparticles
Sych T; Schlegel J; Barriga H; Ojansivu M; Hanke L; Weber F; Bostancioglu B; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; El Andaloussi S; Furth D; Stevens M; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S123
Interpretation of STED-FCS diffusion law plots for nanoscopically heterogeneous membranes
Chmelova B; Koukalova A; Hof M; Sezgin E; Sachl R; Blom H
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S156
High-throughput and correlative membrane biophysical mapping of health and disease
Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S169
Cell biophysical properties unlock a new dimension in defining functional state of cells in health and diseases.
Andronico L; Jang Y; Iskrak S; Ragaller F; Sandoz P; Buggert M; Brodin P; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S164
Correlative spectral STED nanoscopy and STED-FCS elucidate the origin of anomalous diffusion in cellular membranes
Urbancic I; Schneider F; Galiani S; Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S151
Investigating contact formation and biophysical properties at the reconstituted immune synapse
Ragaller F; Andronico L; Achour A; Sezgin E
Preprint: BIORXIV. 2022
A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens
Schlegel J; Porebski B; Andronico L; Hanke L; Edwards S; Brismar H; Murrell B; McInerney G; Fernandez-Capetillo O; Sezgin E
Preprint: BIORXIV. 2022
Single particle profiler for measuring content and properties of nano-sized bioparticles
Sych T; Schlegel J; Barriga HMG; Ojansivu M; Hanke L; Weber F; Bostancioglu RB; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; Andaloussi SE; Fürth D; Stevens MM; Sezgin E
Corrigendum: BIOPHYSICAL REPORTS. 2022;2(2):100057
Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes (vol 1, 100023, 2021)
Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Preprint: BIORXIV. 2022
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Amaro M; Abhinav; Danylchuk DI; Klymchenko A; Hof M; Vattulainen I; Sezgin E
Review: ANNUAL REVIEW OF BIOPHYSICS. 2022;51:135-156
Lipid-Protein Interactions in Plasma Membrane Organization and Function
Sych T; Levental KR; Sezgin E
Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2022;50(2):853-866
Understanding immune signaling using advanced imaging techniques
Brameshuber M; Klotzsch E; Ponjavic A; Sezgin E
Editorial comment: JOURNAL OF CELL SCIENCE. 2022;135(7):jcs259977
Uniting diversity to create a more inclusive academic environment
Delemotte L; Garcia SL; Rodriguez-Gijon A; Sezgin E; Vihervaara A
Preprint: BIORXIV. 2022
Critical role of PCYT2 in muscle health and aging
Cikes D; Elsayad K; Sezgin E; Koitai E; Ferenc T; Orthofer M; Yarwood R; Heinz L; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; al-Murshedi F; Abott A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov A; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain J; Bakovic M; Banka S; Penninger J
Conference publication: 2022;:5
From fluctuations to function: FFS to explore bio-molecular organisation
Schneider F; Cespedes PF; Sezgin E; Fritzsche M; Fraser SE
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):302A
Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5
Reglinski K; Galiani S; Carravilla P; Barbotin A; Urbancic I; Sezgin E; Schneider F; Waithe D; Schliebs W; Erdmann R; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):466A-467A
SFCS provides a window to bio-molecular organization
Schneider F; Cespedes PF; Fraser SE; Sezgin E; Fritzsche M
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):34
Long-term superresolution imaging and quantification of live-cell plasma membrane biophysical properties with smart exchangeable dyes
Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Conference publication: FEBS OPEN BIO. 2022;12:205
Investigation of the functional role of neurotrophin receptor-associated death domain in neuronal development and microglia-glioblastoma interaction using the zebrafish model
Ozalp O; Cark O; Azbazdar Y; Haykir B; Cucun G; Sezgin E; Morisse G; Mazzolini J; Sieger D; Ozhan G
Book chapter: FLUORESCENCE SPECTROSCOPY AND MICROSCOPY IN BIOLOGY: SPRINGER SERIES ON FLUORESCENCE. 2022;p. 323-336
Diffusion Measurements at the Nanoscale with STED-FCS
Schneider F; Sezgin E
Preprint: BIORXIV. 2021
Influence of the extracellular domain size on the dynamic behavior of membrane proteins
Gurdap CO; Wedemann L; Sych T; Sezgin E
Preprint: RESEARCH SQUARE. 2021
Improving bone health via modulation of glycosphingolipid metabolism and autophagy
Leng H; Zhang H; Li L; Zhang S; Wang Y; Chavda S; Galas-Filipowicz D; Ersek A; Morris E; Sezgin E; Lee Y-H; Li Y; Mi J-Q; Yong K; Zhong Q; Edwards C; Simon AK; Horwood N
Preprint: BIORXIV. 2021
STED super-resolution imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes
Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk D; Klymchenko A; Sezgin E; Eggeling C
Preprint: BIORXIV. 2021
Synthetic antigen-presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses
Céspedes PF; Jainarayanan A; Fernández-Messina L; Saliba DG; Valvo S; Kvalvaag A; Chen L; Kurz E; Ganskow C; Colin-York H; Fritzsche M; Peng Y; Dong T; Johnson E; Siller-Farfán JA; Dushek O; Sezgin E; Peacock B; Law A; Aubert D; Engledow S; Attar M; Hester S; Fischer R; Sánchez-Madrid F; Dustin ML
Preprint: BIORXIV. 2021
Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5
Galiani S; Reglinski K; Carravilla P; Barbotin A; Urbančič I; Ott J; Sehr J; Sezgin E; Schneider F; Waithe D; Hublitz P; Schliebs W; Erdmann R; Eggeling C
Review: MEMBRANES. 2021;11(5):323
How Does Liquid-Liquid Phase Separation in Model Membranes Reflect Cell Membrane Heterogeneity?
Sych T; Gurdap CO; Wedemann L; Sezgin E
Preprint: BIORXIV. 2021
A FOXN1 mutation competitively displaces wild-type FOXN1 from higher-order nuclear condensates to cause immunodeficiency
Rota IA; Handel AE; Klein F; Maio S; Dhalla F; Deadman ME; Cheuk S; Newman JA; Michaels YS; Zuklys S; Prevot N; Hublitz P; Charles PD; Gkazi AS; Adamopoulou E; Qasim W; Davies EG; Hanson C; Pagnamenta AT; Camps C; Dreau HM; White A; James K; Fischer R; Gileadi O; Taylor JC; Fulga T; Lagerholm BC; Anderson G; Sezgin E; Holländer GA
Preprint: BIORXIV. 2021
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Hanke L; Das H; Sheward D; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith N; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen G; Coquet J; Hällberg M; Murrell B; McInerney G
Preprint: BIORXIV. 2021
The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease
Leng H; Zhang H; Li L; Zhang S; Wang Y; Ersek A; Morris E; Sezgin E; Lee Y-H; Li Y; Mi J; Zhong Q; Edwards C; Simon AK; Horwood NJ
Review: THE FEBS JOURNAL. 2021;288(4):1070-1090
Model membrane systems to reconstitute immune cell signaling
Cespedes PF; Beckers D; Dustin ML; Sezgin E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)
WASP regulates early B cell receptor signaling and cytoskeletal rearrangements
Saeed M; Taal J; Sezgin E; Blom H; Westerberg L
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:235
Maturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid composition
Luhr JJ; Alex N; Amon L; Kraeter M; Kubankova M; Sezgin E; Lehmann CHK; Heger L; Heidkamp GF; Smith AS; Zaburdaev V; Boeckmann RA; Levental I; Dustin ML; Eggeling C; Guck J; Dudziak D
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation
Matias MI; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Perrault J; Rivière A; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2021;12:740373
Editorial: The Role of Biomembranes and Biophysics in Immune Cell Signaling
Shi Y; Sezgin E; Chen W
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):100
Nanosized lipid particle profiling with fluorescence fluctuometry
Sych T; Plochberger B; Stangl H; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):189
Membrane order change due to lipoprotein particles
Weber F; Axmann M; Sych T; Stangl H; Sezgin E; Plochberger B
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):81
Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbancic I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):80
Nanoscale biophysical properties of plasma membrane
Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):150
Exchangeable polarity-sensitive dyes for real-time quantification of membrane biophysical properties using STED super-resolution microscopy
Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Preprint: BIORXIV. 2020
Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells
Urbančič I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; O’Brien-Ball C; Vuong MT; Ashman N; Sezgin E; Eggeling C
Preprint: BIORXIV. 2020
Lipoprotein particles interact with membranes and transfer their cargo without receptors
Plochberger B; Sych T; Weber F; Novacek J; Axmann M; Stangl H; Sezgin E
Preprint: BIORXIV. 2020
αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
Matias M; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
Preprint: BIORXIV. 2020
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
Oftedal BE; Maio S; Handel A; White MP; Howie D; Davis S; Prevot N; Rota IA; Deadman ME; Kessler BM; Fischer R; Trede NS; Sezgin E; Maizels RM; Holländer GA
Preprint: BIORXIV. 2020
Influence of nanobody binding on fluorescence emission, mobility and organization of GFP-tagged proteins
Schneider F; Eggeling C; Sezgin E
Corrigendum: NATURE CHEMICAL BIOLOGY. 2020;16(6):710
Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
Lorent JH; Levental KR; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova M; Lyman E; Levental I
Preprint: BIORXIV. 2020
Creating supported plasma membrane bilayers using acoustic pressure
Sezgin E; Carugo D; Levental I; Stride E; Eggeling C
Preprint: BIORXIV. 2020
Impact of nanoscale hindrances on the relationship between lipid packing and diffusion in model membranes
Beckers D; Urbancic D; Sezgin E
Preprint: BIORXIV. 2019
z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics
Barbotin A; Urbančič I; Galiani S; Eggeling C; Booth M; Sezgin E
Preprint: BIORXIV. 2019
High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy
Schneider F; Hernandez-Varas P; Lagerholm C; Shrestha D; Sezgin E; Roberti J; Ossato G; Hecht F; Eggeling C; Urbančič I
Preprint: BIORXIV. 2019
Regulation of lipid saturation without sensing membrane fluidity
Ballweg S; Sezgin E; Wunnicke D; Hänelt I; Ernst R
Preprint: BIORXIV. 2019
The mammalian plasma membrane is defined by transmembrane asymmetries in lipid unsaturation, leaflet packing, and protein shape
Lorent J; Levental K; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova; Lyman E; Levental I
Preprint: BIORXIV. 2019
Mechanical properties of plasma membrane vesicles correlate with lipid order and viscosity and depend on cell density
Steinkühler J; Sezgin E; Urbančič I; Eggeling C; Dimova R
Preprint: BIORXIV. 2019
Nanoscale dynamics of cholesterol in the cell membrane
Pinkwart K; Schneider F; Lukoseviciute M; Sauka-Spengler T; Lyman E; Eggeling C; Sezgin E
Preprint: BIORXIV. 2018
Reconstitution of immune cell interactions in free-standing membranes
Jenkins E; Santos AM; Felce J; Hatherley D; Dustin M; Davis S; Eggeling C; Sezgin E
Preprint: BIORXIV. 2018
Nanoscale spatio-temporal diffusion modes measured by simultaneous confocal and STED imaging
Schneider F; Waithe D; Galiani S; de la Serna JB; Sezgin E; Eggeling C
Conference publication: 2018;10500:105000l-22
Interferometric scattering (iSCAT) microscopy: studies of biological membrane dynamics
Reina F; Galiani S; Shrestha D; Sezgin E; Lagerholm BC; Cole D; Kukura P; Eggeling C
Preprint: BIORXIV. 2018
Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation
Sieben C; Sezgin E; Eggeling C; Manley S
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):273A
Cell-Like Mechanical Response in Passive Plasma Membrane Vesicles
Steinkuehler J; Bhatial T; Urbancic I; Sezgin E; Westermann M; Lipowsky R; Dimova R
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):347A-348A
Direct Visualization of Lipoprotein Mediated Cholesterol Transport at the Phospholipid Bilayer Interface
Plochberger B; Axmann M; Sezgin E; Preiner J; Karner A; Roehrl C; Brodesser MD; Eggeling C; Schuetz GJ; Stangl H
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):99A
Advanced STED Microscopy of the Membrane Organization in Activating T-Cells
Urbancic I; Sezgin E; Schneider F; Reina F; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):99A
STED-FCS Reveals Diffusional Heterogeneity of Lipids and GPI-Anchored Proteins in the Plasma Membrane and Actin Cytoskeleton Free Plasma Membrane Vesicles
Schneider F; Waithe D; Clausen MP; Galiani S; Koller T; Ozhan G; Eggeling C; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):108A-109A
Triggering of the High-Affinity IgE Receptor in an AggregationIn-dependent Manner
Felce J; Sezgin E; Wane M; Dustin M; Eggeling C; Davis S
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):16A
Spectral STED Imaging of Cell Membranes
Sezgin E; Schneider F; Zilles V; Urbancic I; Garcia E; Waithe D; Klymchenko A; Eggeling C
Preprint: BIORXIV. 2017
Complementary studies of lipid membrane dynamics using iSCAT and STED microscopy
Reina F; Galiani S; Shrestha D; Sezgin E; de Wit G; Cole D; Lagerholm BC; Kukura P; Eggeling C
Review: JOURNAL OF PHYSICS CONDENSED MATTER. 2017;29(27):273001
Super-resolution optical microscopy for studying membrane structure and dynamics
Sezgin E
Review: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2017;18(6):361-374
The mystery of membrane organization: composition, regulation and roles of lipid rafts
Sezgin E; Levental I; Mayor S; Eggeling C
Preprint: BIORXIV. 2017
Polarity sensitive probes for super resolution STED microscopy
Sezgin E; Schneider F; Zilles V; Garcia E; Waithe D; Klymchenko AS; Eggeling C
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2017;28
Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS.
Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2017;46:S375
Triggering of the high-affinity IgE receptor in an aggregation-independent manner
Felce JH; Sezgin E; Wane M; Dustin ML; Eggeling C; Davis SJ
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2017;46:S251
Ratiometric imaging with super-resolution STED microscopy to reveal nanoscale membrane heterogeneity
Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2017;46:S127
Diffusion of lipids and GPI-anchored proteins in the plasma membrane and actin free vesicles
Schneider F; Sezgin E; Waithe D; Eggeling C
Preprint: BIORXIV. 2016
Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane
Amaro M; Reina F; Hof M; Eggeling C; Sezgin E
Preprint: BIORXIV. 2016
Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS
Schneider F; Clausen M; Waithe D; Koller T; Ozhan G; Eggeling C; Sezgin E
Editorial comment: TRAFFIC. 2016;17(9):1054-1057
Use of BODIPY-Cholesterol (TF-Chol) for Visualizing Lysosomal Cholesterol Accumulation
Holtta-Vuori M; Sezgin E; Eggeling C; Ikonen E
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):521A
Receptor-Mediated HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane
Plochberger B; Roehrl C; Preiner J; Weghuber J; Sezgin E; Hinterdorfer P; Stangl H; Schuetz GJ
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):190A
Membrane Heterogeneity and its Role in Immune Signaling Elucidated by Spectral Imaging
Sezgin E; Eggeling C
Conference publication: THE FEBS JOURNAL. 2016;283:42
Investigating cell membrane dynamics by STED-FCS and spectral imaging
Sezgin E; Eggeling C
Editorial comment: CELL. 2015;161(3):433-434
Membrane Nanoclusters-Tails of the Unexpected
Sezgin E; Davis SJ; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2015;44:S119
Role of membrane heterogeneity in immune signaling studied by model membranes and spectral imaging
Sezgin E; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2014;106(2):392A
HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane
Plochberger B; Schuetz GJ; Roehrl C; Preiner J; Sezgin E; Brameshuber M; Weghuber J; Wieser S; Rankl C; Ruprecht V; Madl J; Bittman R; Hinterdorfer P; Stangl H
Conference publication: BIOPHYSICAL JOURNAL. 2012;102(3):296A-297A
Partitioning, Diffusion, and Ligand Binding of Raft Lipid Analogs in Model and Cellular Plasma Membranes
Sezgin E; Levantal I; Schwarzmann G; Mueller V; Honigmann A; Belov V; Eggeling C; Coskun U; Simons K; Schwille P
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Forskningsbidrag

Genetic and immunological determinants of severe post-acute COVID-19-syndrome
Swedish Research Council
1 December 2021 - 30 November 2024
Correlative cytometry to measure biophysical properties of cells in health and disease
Swedish Research Council
1 January 2021 - 31 December 2024

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