Efthalia Preka
Doktorand
E-postadress: efthalia.preka@ki.se
Besöksadress: BioMedicum A4, Solnavägen 9, 17165 Solna
Postadress: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Blomgren, 171 77 Stockholm
Om mig
- PhD student
I am a PhD student within the Blomgren group, Department of Women's and
Children's Health, Karolinska Institutet.
An engineer with a focus on developmental and computational neuroscience.
Best poster at the NBCNS Research meeting, Gothenburg, November 2022.
MEng Chemical Engineer from the University of Patras, Greece, 2012-2018
Forskningsbeskrivning
- Modern therapies in the paediatric CNS cancer lead to up to 80% 5-year
survival and cranial radiotherapy is a crucial modality in the treatment of
high-grade brain tumours. However, it is considered a major risk for
cognitive impairment in survivors, particularly in children.
My PhD project focuses on unraveling the alterations happening in the
juvenile brain after cranial radiotherapy throughout time. At the same time,
I use classic drugs like lithium as well as a novel award-winning technique,
called antisense oligonucleotides, in order to ameliorate and/or reverse the
irradiation-induced neuroinflammation and cognitive decline in the paediatric
cancer survivors.