Christian Riedel

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Jag är gruppledare vid Institutionen för medicin, Huddinge. Mitt labb arbetar med regleringen av åldrande och åldersrelaterade sjukdomar.
Vänligen klicka på följande länkar till våra laboratoriers webbplatser för mer information:
https://ki.se/en/research/research-areas-centres-and-networks/research-groups/ageing-basic-mechanisms-and-interventions-christian-riedels-research-group
http://riedellab.org

Artiklar

Article: GENOMICS. 2024;116(4):110858
Cactus: A user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis
Salignon J; Millan-Arino L; Garcia MU; Riedel CG
Article: NATURE COMMUNICATIONS. 2024;15(1):2320
The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans
Emerson FJ; Chiu C; Lin LY; Riedel CG; Zhu M; Lee SS
Article: BMC BIOLOGY. 2024;22(1):48
Primary cilia promote the differentiation of human neurons through the WNT signaling pathway
Coschiera A; Yoshihara M; Lauter G; Ezer S; Pucci M; Li H; Kavsek A; Riedel CG; Kere J; Swoboda P
Article: CELL STRESS. 2023;7(12):105-111
A versatile method for the identification of senolytic compounds
Annunziata C; Castoldi F; Schlegel J; Ang HX; Ristovska M; Melini S; Welch R; Riedel CG; Pietrocola F
Journal article: DEVELOPMENT. 2023;150(21):dev201755
SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans.
Robert VJ; Caron M; Gely L; Adrait A; Pakulska V; Couté Y; Chevalier M; Riedel CG; Bedet C; Palladino F
Article: DEVELOPMENT. 2023;150(21):dev201755
SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans
Robert VJ; Caron M; Gely L; Adrait A; Pakulska V; Coute Y; Chevalier M; Riedel CG; Bedet C; Palladino F
Article: AGING. 2023;15(12):5240-5265
Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis
Salignon J; Faridani OR; Miliotis T; Janssens GE; Chen P; Zarrouki B; Sandberg R; Davidsson P; Riedel CG
Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2023;78(1):158-166
Beyond Chronological Age: A Multidimensional Approach to Survival Prediction in Older Adults
Salignon J; Rizzuto D; Calderon-Larranaga A; Zucchelli A; Fratiglioni L; Riedel CG; Vetrano DL
Article: AGING. 2022;14(2):530-543
Meeting Report: Aging Research and Drug Discovery
Meron E; Thaysen M; Angeli S; Antebi A; Barzilai N; Baur JA; Bekker-Jensen S; Birkisdottir M; Bischof E; Bruening J; Brunet A; Buchwalter A; Cabreiro F; Cai S; Chen BH; Ermolaeva M; Ewald CY; Ferrucci L; Florian MC; Fortney K; Freund A; Georgievskaya A; Gladyshev VN; Glass D; Golato T; Gorbunova V; Hoejimakers J; Houtkooper RH; Jager S; Jaksch F; Janssens G; Jensen MB; Kaeberlein M; Karsenty G; de Keizer P; Kennedy B; Kirkland JL; Kjaer M; Kroemer G; Lee K-F; Lemaitre J-M; Liaskos D; Longo VD; Lu Y-X; MacArthur MR; Maier AB; Manakanatas C; Mitchell SJ; Moskalev A; Niedernhofer L; Ozerov I; Partridge L; Passegue E; Petr MA; Peyer J; Radenkovic D; Rando TA; Rattan S; Riedel CG; Rudolph L; Ai R; Serrano M; Schumacher B; Sinclair DA; Smith R; Suh Y; Taub P; Trapp A; Trendelenburg A-U; Valenzano DR; Verburgh K; Verdin E; Vijg J; Westendorp RGJ; Zonari A; Bakula D; Zhavoronkov A; Scheibye-Knudsen M
Article: MOLECULAR METABOLISM. 2021;54:101329
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation
Casteels T; Zhang Y; Frogne T; Sturtzel C; Lardeau C-H; Sen I; Liu X; Hong S; Pauler FM; Penz T; Brandstetter M; Barbieux C; Berishvili E; Heuser T; Bock C; Riedel CG; Meyer D; Distel M; Hecksher-Sorensen J; Li J; Kubicek S
Article: CURRENT PROTOCOLS. 2021;1(7):e187
Chromatin Immunoprecipitation and Sequencing (ChIP-seq) Optimized for Application in Caenorhabditis elegans
Sen I; Kavsek A; Riedel CG
Article: AGING. 2020;12(24):24484-24503
ARDD 2020: from aging mechanisms to interventions
Mkrtchyan GV; Abdelmohsen K; Andreux P; Bagdonaite I; Barzilai N; Brunak S; Cabreiro F; de Cabo R; Campisi J; Cuervo AM; Demaria M; Ewald CY; Fang EF; Faragher R; Ferrucci L; Freund A; Silva-Garcia CG; Georgievskaya A; Gladyshev VN; Glass DJ; Gorbunova V; de Grey A; He W-W; Hoeijmakers J; Hoffmann E; Horvath S; Houtkooper RH; Jensen MK; Jensen MB; Kane A; Kassem M; de Keizer P; Kennedy B; Karsenty G; Lamming DW; Lee K-F; MacAulay N; Mamoshina P; Mellon J; Molenaars M; Moskalev A; Mund A; Niedernhofer L; Osborne B; Pak HH; Parkhitko A; Raimundo N; Rando TA; Rasmussen LJ; Reis C; Riedel CG; Franco-Romero A; Schumacher B; Sinclair DA; Suh Y; Taub PR; Toiber D; Treebak JT; Valenzano DR; Verdin E; Vijg J; Young S; Zhang L; Bakula D; Zhavoronkov A; Scheibye-Knudsen M
Article: CURRENT PROTOCOLS IN PROTEIN SCIENCE. 2020;102(1):e114
Histone Purification Combined with High-Resolution Mass Spectrometry to Examine Histone Post-Translational Modifications and Histone Variants in Caenorhabditis elegans.
Millan-Ariño L; Yuan Z-F; Oomen ME; Brandenburg S; Chernobrovkin A; Salignon J; Körner L; Zubarev RA; Garcia BA; Riedel CG
Article: NATURE COMMUNICATIONS. 2020;11(1):138
DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes
Sen I; Zhou X; Chernobrovkin A; Puerta-Cavanzo N; Kanno T; Salignon J; Stoehr A; Lin X-X; Baskaner B; Brandenburg S; Bjorkegren C; Zubarev RA; Riedel CG
Article: CELL REPORTS. 2019;27(2):467-480.e6
Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging
Janssens GE; Lin X-X; Millan-Arino L; Kavsek A; Sen I; Seinstra RI; Stroustrup N; Nollen EAA; Riedel CG
Article: NATURE COMMUNICATIONS. 2018;9(1):4400
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
Lin X-X; Sen I; Janssens GE; Zhou X; Fonslow BR; Edgar D; Stroustrup N; Swoboda P; Yates JRIII; Ruvkun G; Riedel CG
Article: CELL METABOLISM. 2015;22(1):151-163
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity
Heimbucher T; Liu Z; Bossard C; McCloskey R; Carrano AC; Riedel CG; Tanasa B; Klammt C; Fonslow BR; Riera CE; Lillemeier BF; Kemphues K; Yates JRIII; O'Shea C; Hunter T; Dillin A
Article: NATURE CELL BIOLOGY. 2013;15(5):491-501
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
Riedel CG; Dowen RH; Lourenco GF; Kirienko NV; Heimbucher T; West JA; Bowman SK; Kingston RE; Dillin A; Asara JM; Ruvkun G
Article: CURRENT BIOLOGY. 2012;22(10):881-890
The Caenorhabditis elegans RDE-10/RDE-11 Complex Regulates RNAi by Promoting Secondary siRNA Amplification
Zhang C; Montgomery TA; Fischer SEJ; Garcia SMDA; Riedel CG; Fahlgren N; Sullivan CM; Carrington JC; Ruvkun G
Article: GENES & DEVELOPMENT. 2011;25(19):2079-2092
The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA
Hayes GD; Riedel CG; Ruvkun G
Article: PLOS GENETICS. 2011;7(9):e1002235
The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO
Rizki G; Iwata TN; Li J; Riedel CG; Picard CL; Jan M; Murphy CT; Lee SS
Article: CELL CYCLE. 2010;9(20):4048-4049
Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.
Riedel CG
Article: CELL CYCLE. 2010;9(13):2657-2662
Casein kinase 1 is required for efficient removal of Rec8 during meiosis I
Rumpf C; Cipak L; Dudas A; Benko Z; Pozgajova M; Riedel CG; Ammerer G; Mechtler K; Gregan J
Article: NATURE. 2009;459(7250):1079-1U60
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
Curran SP; Wu X; Riedel CG; Ruvkun G
Article: CURRENT BIOLOGY. 2007;17(14):1190-1200
The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation
Gregan J; Riedel CG; Pidoux AL; Katou Y; Rumpf C; Schleiffer A; Kearsey SE; Shirahige K; Allshire RC; Nasmyth K
Article: NATURE PROTOCOLS. 2007;2(5):1145-1151
Tandem affinity purification of functional TAP-tagged proteins from human cells
Gregan J; Riedel CG; Petronczki M; Cipak L; Rumpf C; Poser I; Buchholz F; Mechtler K; Nasmyth K
Article: NATURE. 2006;441(7089):53-61
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Riedel CG; Katis VL; Katou Y; Mori S; Itoh T; Helmhart W; Gálova M; Petronczki M; Gregan J; Cetin B; Mudrak I; Ogris E; Mechtler K; Pelletier L; Buchholz F; Shirahige K; Nasmyth K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(45):37846-37852
Differential requirement for phospholipase D/Spo14 and its novel interactor Sma1 for regulation of exocytotic vesicle fusion in yeast meiosis
Riedel CG; Mazza M; Maier P; Körner R; Knop M
Article: TRENDS IN BIOCHEMICAL SCIENCES. 2004;29(8):389-392
Is chromatin remodeling required to build sister-chromatid cohesion?
Riedel CG; Gregan J; Gruber S; Nasmyth K
Article: BIOTECHNIQUES. 2002;33(3):592-602
Improved version of the red fluorescent protein (drFP583/DsRed/RFP)
Knop M; Barr F; Riedel CG; Heckel T; Reichel C
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Alla övriga publikationer

Preprint: BIORXIV. 2023;BIORXIV
The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans.
Emerson FJ; Chiu C; Lin LY; Riedel CG; Zhu M; Lee SS
Preprint: BIORXIV. 2022
A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation
Breusegem SY; Houghton J; Romero-Bueno R; Fragoso-Luna A; Kentistou KA; Ong KK; Janssen AFJ; Bright NA; Riedel CG; Perry JRB; Askjaer P; Larrieu D
Review: CURRENT GENOMICS. 2018;19(6):464-482
Regulation of Age-related Decline by Transcription Factors and Their Crosstalk with the Epigenome
Zhou X; Sen I; Lin X-X; Riedel CG
Book chapter: CHROMATIN REGULATION AND DYNAMICS. 2017;p. 95-116
Chapter 4 ATP-Dependent Chromatin Remodeling: From Development to Disease
Lezzerini M; Riedel CG
Other: CELL CYCLE. 2010;9(20):4048-4049
Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.
Riedel CG

Forskningsbidrag

Discovery of new chromatin-related mechanisms that delay or prevent aging
Swedish Research Council
1 January 2024 - 31 December 2027
A new mechanism by which mitochondria modulate the outcomes of reduced insulin/IGF-like signaling and slow down the aging process
Novo Nordisk Foundation
1 January 2023 - 31 December 2024
A new mechanism by which mitochondria modulate the outcomes of reduced insulin/IGF-like signaling and slow down the aging process
Novo Nordisk Foundation
1 January 2022 - 31 December 2022
Molecular Profiling and Novel Treatment Strategies of Vascular Ageing in Chronic Kidney Disease
Swedish Research Council
1 January 2022 - 31 December 2024
New mechanistic insights into aging regulation by the transcription factor DAF-16/FOXO
Swedish Research Council
1 January 2020 - 31 December 2023
Disentangling complexity of health in aging: A new research environment to pave the road for individualized medicine
Swedish Research Council
1 December 2017 - 31 December 2022
Regulation of aging by DAF-16/FOXO, its cofactors, and the chromatin landscape
Swedish Research Council
1 January 2016 - 31 December 2019
Molecular mechanisms of longevity control
International Human Frontier Science Program Organization
1 May 2008 - 30 April 2011

Anställningar

Associate Professor, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 2024-
Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
Professor, Chair of Nutritional Physiology, Faculty of Lifesciences, University of Bayreuth, 2023-2024
Assistant Professor, European Research Institute for the Biology of Ageing, University Medical Center Groningen, 2013-2015
Postdoctoral Fellow, Dept of Molecular Biology, Massachusetts General Hospital, 2007-2012

Examina och utbildning

Molecular Biology, Research Institute of Molecular Pathology, 2006
Biochemistry, University of Tübingen, 2001

Om mig

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI