Cecilia Mörman

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Journal article: BIOPHYSICAL JOURNAL. 2024;123(3):413a-414a

The anti-amyloid BRICHOS domain regulates tau protein liquid-liquid phase separation and inhibits tau fibrillation associated with Alzheimer’s disease

Mörman C; Leppert A; Johansson J; Luo J; Abelein A
Article: COMMUNICATIONS CHEMISTRY. 2023;6(1):163

13C- and 15N-labeling of amyloid-β and inhibitory peptides to study their interaction via nanoscale infrared spectroscopy.

Paul S; Jeništová A; Vosough F; Berntsson E; Mörman C; Jarvet J; Gräslund A; Wärmländer SKTS; Barth A
Article: COMMUNICATIONS CHEMISTRY. 2022;5(1):171

Multivariate effects of pH, salt, and Zn2+ ions on Aβ40 fibrillation.

Wang H; Wu J; Sternke-Hoffmann R; Zheng W; Mörman C; Luo J
Article: JACS AU. 2022;2(11):2571-2584

Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease.

Abelein A; Ciofi-Baffoni S; Mörman C; Kumar R; Giachetti A; Piccioli M; Biverstål H
Article: JOURNAL OF INORGANIC BIOCHEMISTRY. 2022;236:111945

Cu2+ ions modulate the interaction between α-synuclein and lipid membranes.

Wang H; Mörman C; Sternke-Hoffmann R; Huang C-Y; Prota A; Ma P; Luo J
Article: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL. 2022;20:5672-5679

Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity.

Gallego-Villarejo L; Wallin C; Król S; Enrich-Bengoa J; Suades A; Aguilella-Arzo M; Gomara MJ; Haro I; Wärmlander S; Muñoz FJ; Gräslund A; Perálvarez-Marín A
Article: ISCIENCE. 2021;24(8):102852

The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments.

Król S; Österlund N; Vosough F; Jarvet J; Wärmländer S; Barth A; Ilag LL; Magzoub M; Gräslund A; Mörman C
Article: JOURNAL OF IMMUNOLOGY. 2021;207(3):974-984

Citrullination Alters the Antibacterial and Anti-Inflammatory Functions of the Host Defense Peptide Canine Cathelicidin K9CATH In Vitro.

Al Adwani S; Padhi A; Karadottir H; Mörman C; Gräslund A; Végvári Á; Johansson J; Rising A; Agerberth B; Bergman P
Article: JOURNAL OF MOLECULAR BIOLOGY. 2021;433(2):166717

ATP Impedes the Inhibitory Effect of Hsp90 on Aβ40 Fibrillation.

Wang H; Lallemang M; Hermann B; Wallin C; Loch R; Blanc A; Balzer BN; Hugel T; Luo J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(21):7224-7234

Metal ion coordination delays amyloid-β peptide self-assembly by forming an aggregation-inert complex.

Wallin C; Jarvet J; Biverstål H; Wärmländer S; Danielsson J; Gräslund A; Abelein A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376

Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties.

Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Végvári Á; Smith ME; Qvarfordt I; Lindén A; Gräslund A; Agerberth B; Bergman P
Article: CELL REPORTS PHYSICAL SCIENCE. 2020;1(2):100014

Designed Cell-Penetrating Peptide Inhibitors of Amyloid-beta Aggregation and Cytotoxicity

Henning-Knechtel A; Kumar S; Wallin C; Krol S; Warmlander SKTS; Jarvet J; Esposito G; Kirmizialtin S; Graslund A; Hamilton AD; Magzoub M
Article: BIOMOLECULES. 2019;10(1):E44-44

Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization.

Wallin C; Friedemann M; Sholts SB; Noormägi A; Svantesson T; Jarvet J; Roos PM; Palumaa P; Gräslund A; Wärmländer SKTS
Article: ACS CHEMICAL BIOLOGY. 2019;14(7):1410-1417

Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs.

Pansieri J; Ostojić L; Iashchishyn IA; Magzoub M; Wallin C; Wärmländer SKTS; Gräslund A; Nguyen Ngoc M; Smirnovas V; Svedružić Ž; Morozova-Roche LA
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;510(4):520-524

Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin).

Dong X; Svantesson T; Sholts SB; Wallin C; Jarvet J; Gräslund A; Wärmländer SKTS
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(7):1680-1692

Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects.

Österlund N; Kulkarni YS; Misiaszek AD; Wallin C; Krüger DM; Liao Q; Mashayekhy Rad F; Jarvet J; Strodel B; Wärmländer SKTS; Ilag LL; Kamerlin SCL; Gräslund A
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2018;140(26):8138-8146

The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage.

Wallin C; Hiruma Y; Wärmländer SKTS; Huvent I; Jarvet J; Abrahams JP; Gräslund A; Lippens G; Luo J
Article: JOURNAL OF NEUROINFLAMMATION. 2018;15(1):172

Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.

Horvath I; Iashchishyn IA; Moskalenko RA; Wang C; Wärmländer SKTS; Wallin C; Gräslund A; Kovacs GG; Morozova-Roche LA
Article: JOURNAL OF MOLECULAR BIOLOGY. 2018;430(3):348-362

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.

Teixeira PF; Masuyer G; Pinho CM; Branca RMM; Kmiec B; Wallin C; Wärmländer SKTS; Berntsson RP-A; Ankarcrona M; Gräslund A; Lehtiö J; Stenmark P; Glaser E
Article: SCIENTIFIC REPORTS. 2017;7(1):14423

Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation.

Wallin C; Sholts SB; Österlund N; Luo J; Jarvet J; Roos PM; Ilag L; Gräslund A; Wärmländer SKTS
Article: ENVIRONMENTAL HEALTH. 2017;16(1):61

Ancient water bottle use and polycyclic aromatic hydrocarbon (PAH) exposure among California Indians: a prehistoric health risk assessment.

Sholts SB; Smith K; Wallin C; Ahmed TM; Wärmländer SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2016;38:183-193

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease.

Wallin C; Kulkarni YS; Abelein A; Jarvet J; Liao Q; Strodel B; Olsson L; Luo J; Abrahams JP; Sholts SB; Roos PM; Kamerlin SCL; Gräslund A; Wärmländer SKTS
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;54(3):971-982

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.

Tiiman A; Luo J; Wallin C; Olsson L; Lindgren J; Jarvet J; Per R; Sholts SB; Rahimipour S; Abrahams JP; Karlström AE; Gräslund A; Wärmländer SKTS
Article: CHEMISTRY-A EUROPEAN JOURNAL. 2016;22(40):14236-14246

Self-Assembled Cyclic d,l-α-Peptides as Generic Conformational Inhibitors of the α-Synuclein Aggregation and Toxicity: In Vitro and Mechanistic Studies.

Chemerovski-Glikman M; Rozentur-Shkop E; Richman M; Grupi A; Getler A; Cohen HY; Shaked H; Wallin C; Wärmländer SKTS; Haas E; Gräslund A; Chill JH; Rahimipour S
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Preprint: BIORXIV. 2024

Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions

Leppert A; Feng J; Railaite V; Bohn Pessatti T; Mörman C; Os-terholz H; Maia FRNC; Linder M; Rising A; Landreh M
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S97

The anti-amyloid chaperone BRICHOS regulates Tau liquid-liquid phase separation and inhibits Tau fibrillation

Morman C; Leppert A; Johansson J; Luo J; Abelein A
Review: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2019;24(8):1189-1196

Metal binding to the amyloid-β peptides in the presence of biomembranes: potential mechanisms of cell toxicity.

Wärmländer SKTS; Österlund N; Wallin C; Wu J; Luo J; Tiiman A; Jarvet J; Gräslund A
Review: ISRAEL JOURNAL OF CHEMISTRY. 2017;57(7-8):674-685

The Amyloid-β Peptide in Amyloid Formation Processes: Interactions with Blood Proteins and Naturally Occurring Metal Ions

Wallin C; Luo J; Jarvet J; Waermlaender SKTS; Graslund A

Forskningsbidrag

A new phase in understanding Alzheimer’s disease: Identification and characterization of the relationship between Tau liquid-liquid phase separation and cellular consequences

Swedish Research Council

1 July 2021 - 30 June 2024

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