Cecilia Mörman

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Articles

Journal article: BIOPHYSICAL JOURNAL. 2024;123(3):413a-414a
The anti-amyloid BRICHOS domain regulates tau protein liquid-liquid phase separation and inhibits tau fibrillation associated with Alzheimer's disease
Morman C; Leppert A; Johansson J; Luo J; Abelein A
Article: COMMUNICATIONS CHEMISTRY. 2023;6(1):163
¹³C- and ¹⁵N-labeling of amyloid-β and inhibitory peptides to study their interaction via nanoscale infrared spectroscopy
Paul S; Jenistova A; Vosough F; Berntsson E; Moerman C; Jarvet J; Graeslund A; Waermlaender SKTS; Barth A
Article: COMMUNICATIONS CHEMISTRY. 2022;5(1):171
Multivariate effects of pH, salt, and Zn²⁺ ions on Aβ₄₀ fibrillation
Wang H; Wu J; Sternke-Hoffmann R; Zheng W; Morman C; Luo J
Article: JACS AU. 2022;2(11):2571-2584
Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease
Abelein A; Ciofi-Baffoni S; Morman C; Kumar R; Giachetti A; Piccioli M; Biverstal H
Article: JOURNAL OF INORGANIC BIOCHEMISTRY. 2022;236:111945
Cu²⁺ ions modulate the interaction between ?-synuclein and lipid membranes
Wang H; Morman C; Sternke-Hoffmann R; Huang C-Y; Prota A; Ma P; Luo J
Article: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL. 2022;20:5672-5679
Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity.
Gallego-Villarejo L; Wallin C; Król S; Enrich-Bengoa J; Suades A; Aguilella-Arzo M; Gomara MJ; Haro I; Wärmlander S; Muñoz FJ; Gräslund A; Perálvarez-Marín A
Article: ISCIENCE. 2021;24(8):102852
The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments.
Król S; Österlund N; Vosough F; Jarvet J; Wärmländer S; Barth A; Ilag LL; Magzoub M; Gräslund A; Mörman C
Article: JOURNAL OF IMMUNOLOGY. 2021;207(3):974-984
Citrullination Alters the Antibacterial and Anti-Inflammatory Functions of the Host Defense Peptide Canine Cathelicidin K9CATH In Vitro
Al Adwani S; Padhi A; Karadottir H; Morman C; Graslund A; Vegvari A; Johansson J; Rising A; Agerberth B; Bergman P
Article: JOURNAL OF MOLECULAR BIOLOGY. 2021;433(2):166717
ATP Impedes the Inhibitory Effect of Hsp90 on Aβ40 Fibrillation.
Wang H; Lallemang M; Hermann B; Wallin C; Loch R; Blanc A; Balzer BN; Hugel T; Luo J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(21):7224-7234
Metal ion coordination delays amyloid-? peptide self-assembly by forming an aggregation?inert complex
Wallin C; Jarvet J; Biverstal H; Warmlander S; Danielsson J; Graslund A; Abelein A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Article: CELL REPORTS PHYSICAL SCIENCE. 2020;1(2):100014
Designed Cell-Penetrating Peptide Inhibitors of Amyloid-beta Aggregation and Cytotoxicity
Henning-Knechtel A; Kumar S; Wallin C; Krol S; Warmlander SKTS; Jarvet J; Esposito G; Kirmizialtin S; Graslund A; Hamilton AD; Magzoub M
Article: BIOMOLECULES. 2019;10(1):E44-44
Mercury and Alzheimer's Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization
Wallin C; Friedemann M; Sholts SB; Noormaegi A; Svantesson T; Jarvet J; Roos PM; Palumaa P; Graslund A; Waermlaender SKTS
Article: ACS CHEMICAL BIOLOGY. 2019;14(7):1410-1417
Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs
Pansieri J; Ostojic L; Iashchishyn IA; Magzoub M; Wallin C; Warmlander SKTS; Graslund A; Mai NN; Smirnovas V; Svedruzic Z; Morozova-Roche LA
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;510(4):520-524
Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin).
Dong X; Svantesson T; Sholts SB; Wallin C; Jarvet J; Gräslund A; Wärmländer SKTS
Article: ACS CHEMICAL NEUROSCIENCE. 2018;9(7):1680-1692
Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects
Osterlund N; Kulkarni YS; Misiaszek AD; Wallin C; Krueger DM; Liao Q; Rad FM; Jarvet J; Strodel B; Warmlander SKTS; Ilag LL; Kamerlin SCL; Graslund A
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2018;140(26):8138-8146
The Neuronal Tau Protein Blocks in Vitro Fibrillation of the Amyloid-β (Aβ) Peptide at the Oligomeric Stage
Wallin C; Hiruma Y; Warmlander SKTS; Huvent I; Jarvet J; Abrahams JP; Graslund A; Lippens G; Luo J
Article: JOURNAL OF NEUROINFLAMMATION. 2018;15(1):172
Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.
Horvath I; Iashchishyn IA; Moskalenko RA; Wang C; Wärmländer SKTS; Wallin C; Gräslund A; Kovacs GG; Morozova-Roche LA
Article: JOURNAL OF MOLECULAR BIOLOGY. 2018;430(3):348-362
Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin
Teixeira PF; Masuyer G; Pinho CM; Branca RMM; Kmiec B; Wallin C; Warmlander SKTS; Berntsson RP-A; Ankarcrona M; Graslund A; Lehtio J; Stenmark P; Glaser E
Article: SCIENTIFIC REPORTS. 2017;7(1):14423
Alzheimer's disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation
Wallin C; Sholts SB; Osterlund N; Luo J; Jarvet J; Roos PM; Ilag L; Graslund A; Warmlander SKTS
Article: ENVIRONMENTAL HEALTH: A GLOBAL ACCESS SCIENCE SOURCE. 2017;16(1):61
Ancient water bottle use and polycyclic aromatic hydrocarbon (PAH) exposure among California Indians: a prehistoric health risk assessment.
Sholts SB; Smith K; Wallin C; Ahmed TM; Wärmländer SKTS
Article: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY. 2016;38:183-193
Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease
Wallin C; Kulkarni YS; Abelein A; Jarvet J; Liao Q; Strodel B; Olsson L; Luo J; Abrahams JP; Sholts SB; Roos PM; Kamerlin SCL; Graslund A; Warmlander SKTS
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2016;54(3):971-982
Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species
Tiiman A; Luo J; Wallin C; Olsson L; Lindgren J; Jarvet J; Roose P; Sholts SB; Rahimipour S; Abrahams JP; Karlstrom AE; Graslund A; Warmlander SKTS
Article: CHEMISTRY - A EUROPEAN JOURNAL. 2016;22(40):14236-14246
Self-Assembled Cyclic d,l-α-Peptides as Generic Conformational Inhibitors of the α-Synuclein Aggregation and Toxicity: In Vitro and Mechanistic Studies.
Chemerovski-Glikman M; Rozentur-Shkop E; Richman M; Grupi A; Getler A; Cohen HY; Shaked H; Wallin C; Wärmländer SKTS; Haas E; Gräslund A; Chill JH; Rahimipour S
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Preprint: BIORXIV. 2024
Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions
Leppert A; Feng J; Railaite V; Bohn Pessatti T; Mörman C; Os-terholz H; Maia FRNC; Linder M; Rising A; Landreh M
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2023;52(SUPPL 1):S97
The anti-amyloid chaperone BRICHOS regulates Tau liquid-liquid phase separation and inhibits Tau fibrillation
Morman C; Leppert A; Johansson J; Luo J; Abelein A
Review: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2019;24(8):1189-1196
Metal binding to the amyloid-β peptides in the presence of biomembranes: potential mechanisms of cell toxicity
Warmlander SKTS; Osterlund N; Wallin C; Wu J; Luo J; Tiiman A; Jarvet J; Graslund A
Review: ISRAEL JOURNAL OF CHEMISTRY. 2017;57(7-8):674-685
The Amyloid-β Peptide in Amyloid Formation Processes: Interactions with Blood Proteins and Naturally Occurring Metal Ions
Wallin C; Luo J; Jarvet J; Waermlaender SKTS; Graslund A

Grants

A new phase in understanding Alzheimer’s disease: Identification and characterization of the relationship between Tau liquid-liquid phase separation and cellular consequences
Swedish Research Council
1 July 2021 - 30 June 2024

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