Carolyn Cesta

Carolyn Cesta

Biträdande Lektor
E-postadress: carolyn.cesta@ki.se
Besöksadress: Maria Aspmans gata 30A, 17164 Solna
Postadress: K2 Medicin, Solna, K2 KEP Kieler H, 171 77 Stockholm

Om mig

  • Se min hemsida på engelska.

Utvalda publikationer

Artiklar

Alla övriga publikationer

Forskningsbidrag

  • Swedish Research Council
    1 January 2025 - 31 December 2028
    Semaglutide and other GLP-1 receptor agonists (GLP-1 RA) have revolutionized the treatment of type 2 diabetes and obesity and their use in Sweden and globally has increased dramatically since 2020. Women are more likely to be overweight or obese which is associated with infertility and adverse pregnancy outcomes. GLP-1 RA may be an effective tool to lose weight before pregnancy and while it is advised that they are discontinued two months prior to conception, up to 50% of pregnancies are unplanned. Unintended GLP-1 RA exposure in early pregnancy is a real possibility and it is unknown if they increase the risk of malformations in infants. Additionally, even if GLP-1 RA are discontinued as recommended, there is a chance of excessive weight gain in pregnancy which is associated with adverse pregnancy outcomes, such as gestational diabetes.This project aims to fill this knowledge gap through observational studies using a common protocol in data from Swedish population health registers and from other Nordic and international collaborators. First, utilization patterns and characteristics of women using GLP-1 RA will be described. Then the risk for adverse pregnancy outcomes will be compared between exposed and unexposed pregnancies from women with similar body mass index. High quality evidence will be generated in a timely manner to help avoid unnecessary harm. Results may also provide reassurance to those who can benefit from these new pharmacotherapies.
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2022 - 31 December 2024
  • InPreSS – International Pregnancy Safety Study
    Marie Skłodowska-Curie Actions Global Fellowship, , European Commission, Horizon 2020
    1 September 2020 - 4 March 2023

Anställningar

  • Biträdande Lektor, Medicin, Solna, Karolinska Institutet, 2023-2029

Examina och utbildning

  • Docent, Karolinska Institutet, 2024
  • Medicine Doktorsexamen, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2017

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