Brun Ulfhake
Professor, Senior
E-postadress: brun.ulfhake@ki.se
Besöksadress: Alfred Nobels allé 8, 14152 Huddinge
Postadress: H5 Laboratoriemedicin, H5 Klin Fysiologi, 141 52 Huddinge
Om mig
- Brun Ulfhake föddes i Stockholm 1952 och tog läkarexamen vid Karolinska Institutet 1980. Läkarutbildningen varvades med forskning
- 1982 disputerade han på en avhandling om elektriska egenskaper, funktion och struktur hos centrala nervceller. Därefter var han kliniskt verksam, bland annat som anestesiolog och dykläkare, respektive bedrev neurobiologisk forskning vid Karolinska Institutet. 1988 blev han docent och 1994 universitetslektor. En period i början av 1990-talet tillbringade Brun Ulfhake som postdoktor vid NIH, USA, och han har sedan 1991 forskat vid Karolinska Institutet kring sambandet mellan vår arvsmassa och förändringar i nervsystemets funktion under åldrandet.
Brun Ulfhake utnämndes den 1 mars 2001 till professor i anatomi vid Karolinska Institutet.
Brun Ulfhake har haft ett flertal engagemang inom såväl undervisningen vid Karolinska Institutet som djurförsöksetiska frågor - bland annat som studierektor för anatomiutbildningen. Sedan 1 januari 2013 är Brun Ulfhake verksamhetschef för Komparativ medicin.
Forskningsbeskrivning
- Åldrandet är oundvikligt och samtidigt en ojämlik process där vissa personer blir en bra bit över hundra medan andra får ett betydligt kortare liv. Det som avgör är samspelet mellan vår arvsmassa och vårt beteende i kombination med olika epigenetiska, omgivningsrelaterade, faktorer. Forskningen syftar till att skapa förståelse för vilka arvsanlag och genregleringar som ligger bakom de funktionsnedsättningar som kommer med stigande ålder. Den kunskapen kan sedan användas till att mildra åldrandets negativa konsekvenser för individen.
Artiklar
- Article: ATLA ALTERNATIVES TO LABORATORY ANIMALS. 2023;51(6):376-386
- Article: BIOLOGY. 2023;12(9):1177
- Article: PLOS ONE. 2023;18(6):e0280416
- Article: CELL RESEARCH. 2021;31(12):1244-1262
- Article: SCIENTIFIC REPORTS. 2021;11(1):4961
- Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(4):654-663
- Article: THE FASEB JOURNAL. 2020;34(2):2024-2040
- Article: ACTA PHYSIOLOGICA. 2019;227(3):e13335
- Article: HUMAN MOLECULAR GENETICS. 2015;24(5):1305-1321
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2015;43(D1):D1171-D1175
- Article: EXPERIMENTAL GERONTOLOGY. 2013;48(11):1173-1179
- Article: AGE. 2012;34(6):1435-1452
- Article: JOURNAL OF PHYSIOLOGY. 2012;590(23):6187-6197
- Article: NEUROBIOLOGY OF AGING. 2011;32(10):1868-1880
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(51):39597-39608
- Article: PHYSIOLOGY AND BEHAVIOR. 2007;92(5):911-923
- Article: PHYSIOLOGY AND BEHAVIOR. 2007;92(1-2):129-135
- Article: MUSCLE AND NERVE. 2007;36(2):223-233
- Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2006;61(7):663-674
- Article: JOURNAL OF CHEMICAL NEUROANATOMY. 2006;31(1):2-36
- Article: AGING CELL. 2005;4(2):65-77
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2004;78(6):892-900
- Article: EXPERIMENTAL BRAIN RESEARCH. 2003;149(4):447-457
- Article: AGING CELL. 2003;2(1):47-57
- Article: ANATOMICAL RECORD. 2002;266(4):226-233
- Article: NEUROBIOLOGY OF AGING. 2002;23(2):271-286
- Article: JOURNAL OF NEUROSCIENCE METHODS. 2001;108(1):19-24
- Article: BRAIN RESEARCH. 2001;899(1-2):169-186
- Article: NEUROSCIENCE. 2001;105(1):249-263
- Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000;12(8):2694-2706
- Article: NEUROSCIENCE LETTERS. 1999;273(3):187-190
- Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1999;11(8):2935-2948
- Article: JOURNAL OF NEUROSCIENCE RESEARCH. 1999;57(2):153-165
- Article: NEUROREPORT. 1999;10(7):1529-1535
- Article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 1998;53(5):B369-B379
- Article: JOURNAL OF COMPARATIVE NEUROLOGY. 1998;396(2):211-222
- Article: JOURNAL OF NEUROSCIENCE METHODS. 1998;80(2):129-136
- Article: EXPERIMENTAL BRAIN RESEARCH. 1998;118(4):517-532
- Article: EXPERIMENTAL BRAIN RESEARCH. 1997;117(2):324-340
- Article: NATURE BIOTECHNOLOGY. 1997;15(4):373-377
- Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1996;8(3):494-499
- Article: JOURNAL OF COMPARATIVE NEUROLOGY. 1996;365(3):413-426
- Article: NEUROREPORT. 1995;6(15):1975-1980
- Article: BRAIN RESEARCH. 1995;33(1):87-96
- Article: JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY. 1995;43(7):699-707
- Article: NEUROREPORT. 1995;6(8):1169-1173
- Journal article: JOURNAL OF CHEMICAL NEUROANATOMY. 1994;7(4):203-215
- Journal article: JOURNAL OF CHEMICAL NEUROANATOMY. 1994;7(1-2):3-12
- Journal article: JOURNAL OF CHEMICAL NEUROANATOMY. 1994;7(1-2):87-103
- Journal article: JOURNAL OF CHEMICAL NEUROANATOMY. 1994;7(4):285-287
- Journal article: JOURNAL OF CHEMICAL NEUROANATOMY. 1994;7(4):289-298
- Journal article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1993;5(10):1321-1333
- Journal article: NEUROREPORT. 1993;4(7):849-856
- Journal article: METHODS. 1993;2(2):75-77
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1993;97(1):1-12
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1993;96(3):404-418
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1992;322(3):293-310
- Journal article: BRAIN RESEARCH. 1992;585(1-2):400-404
- Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1992;657:119-134
- Journal article: SYNAPSE. 1992;11(2):85-104
- Journal article: JOURNAL OF NEUROSCIENCE. 1992;12(6):2403-2416
- Journal article: NEUROREPORT. 1992;3(4):303-306
- Journal article: JOURNAL OF NEUROSCIENCE. 1992;12(3):718-728
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1992;316(1):1-16
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1992;91(2):284-295
- Journal article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;4(8):777-784
- Journal article: JOURNAL OF NEUROSCIENCE METHODS. 1991;40(1):39-48
- Journal article: DEVELOPMENTAL BRAIN RESEARCH. 1991;62(2):189-202
- Journal article: BRAIN RESEARCH. 1991;558(2):330-334
- Journal article: PEPTIDES. 1991;34(2):78
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1991;308(1):115-138
- Journal article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1991;3(10):1036
- Journal article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1991;3(8):737-757
- Journal article: ACTA PHYSIOLOGICA. 1990;140(4):501-506
- Journal article: BRAIN RESEARCH. 1990;534(1-2):352-356
- Journal article: BRAIN RESEARCH. 1990;532(1-2):47-57
- Journal article: JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY. 1990;38(2):179-190
- Journal article: RESTORATIVE NEUROLOGY AND NEUROSCIENCE. 1990;1(3):289-295
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1990;79(1):212-216
- Journal article: SYNAPSE. 1990;6(3):237-270
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1990;80(1):34-43
- Journal article: BRAIN RESEARCH. 1989;489(2):387-391
- Journal article: NEUROSCIENCE. 1989;29(3):725-733
- Journal article: BRAIN RESEARCH BULLETIN. 1989;22(1):93-102
- Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1989;553:76-105
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1988;278(1):88-102
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1988;278(1):69-87
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1988;278(1):103-120
- Journal article: REGULATORY PEPTIDES. 1988;22(1-2):6-8
- Journal article: ACTA PHYSIOLOGICA. 1988;132(3):353-362
- Journal article: PROGRESS IN BRAIN RESEARCH. 1988;78:225-229
- Journal article: BRAIN RESEARCH. 1987;419(1-2):387-391
- Journal article: NEUROSCIENCE LETTERS. 1987;73(1):3-8
- Journal article: ACTA PHYSIOLOGICA. 1987;129(1):61-66
- Journal article: ACTA PHYSIOLOGICA. 1986;128(3):485-494
- Journal article: NEUROSCIENCE LETTERS. 1986;70(1):23-27
- Journal article: ACTA PHYSIOLOGICA. 1986;126(4):565-573
- Journal article: NEUROSCIENCE LETTERS. 1986;63(1):27-32
- Journal article: BRAIN RESEARCH. 1985;23(2):193-200
- Journal article: BRAIN RESEARCH. 1985;17(1-2):63-73
- Journal article: BRAIN RESEARCH. 1984;307(1-2):167-179
- Journal article: EXPERIMENTAL BRAIN RESEARCH. 1984;56(2):327-334
- Journal article: BRAIN RESEARCH. 1983;264(1):1-19
- Journal article: BRAIN RESEARCH. 1982;251(2):201-209
- Journal article: BRAIN RESEARCH. 1982;5(2):234-237
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1981;202(4):571-583
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1981;202(4):585-596
- Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 1979;188(4):679-686
- Journal article: NEUROSCIENCE LETTERS. 1979;13(1):47-50
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Alla övriga publikationer
- Review: BMC BIOLOGY. 2023;21(1):256
- Preprint: PREPRINTS.ORG. 2023
- Preprint: BIORXIV. 2023
- Review: FRONTIERS IN GENETICS. 2021;12:688526
- Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2012;113(4):680-684
- Book chapter: SENESCENCE. 2012;p.
- Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2012;113(4):683-684
- Review: JOURNAL OF COMPARATIVE NEUROLOGY. 2005;488(2):152-179
- Book chapter: PERIPHERAL NEUROPATHY. 2005;p. v-xv
- Book chapter: PERIPHERAL NEUROPATHY. 2005;p. 483-507
- Published conference paper: AUTONOMIC NEUROSCIENCE: BASIC AND CLINICAL. 2002;96(1):43-49
- Review: MOLECULAR NEUROBIOLOGY. 2000;21(3):109-135
- Published conference paper: JOURNAL OF CHEMICAL NEUROANATOMY. 2000;18(1-2):75-86
- Review: JOURNAL OF COMPARATIVE NEUROLOGY. 1999;410(3):368-386
- Review: BRAIN RESEARCH. 1999;69(1):21-34
- Review: JOURNAL OF COMPARATIVE NEUROLOGY. 1996;375(2):303-319
- Review: JOURNAL OF COMPARATIVE NEUROLOGY. 1995;359(1):69-89
- Conference publication: PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. 1995;2412:124-130
- Published conference paper: ZOOLOGICAL STUDIES. 1995;34:56-58
- Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;:125
- Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;:169
- Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;:169
- Book chapter: COMPUTERS AND COMPUTATIONS IN THE NEUROSCIENCES - METHODS IN NEUROSCIENCES: METHODS IN NEUROSCIENCES. 1992;p. 94-128
- Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;:268
- Conference publication: EUROPEAN JOURNAL OF NEUROSCIENCE. 1992;:137
- Book chapter: SEROTONIN. 1990;p. 149-154
- Book chapter: NEUROBIOLOGY OF EARLY INFANT BEHAVIOUR. 1989;p. 51-58
- Book chapter: PROGRESS IN BRAIN RESEARCH. 1988;p. 225-229
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Forskningsbidrag
- Förändringar i muskelstyrka under åldrandet–kunskap som kan leda till ett fysiskt aktivt livcentrum för idrottsforskning1 January 2024 - 31 December 2023
- Förändringar i muskelstyrka under åldrandet–kunskap som kan leda till ett fysiskt aktivt livCentrum för idrottsforskning1 January 2023 - 31 December 2023
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council1 January 2009 - 31 December 2011