Birgitta Henriques-Normark

Article: JOURNAL OF IMMUNOLOGY. 2024;212(1):69-80

STAT3 Deficiency Alters the Macrophage Activation Pattern and Enhances Matrix Metalloproteinase 9 Expression during Staphylococcal Pneumonia

Farmand S; Sender V; Karlsson J; Merkl P; Normark S; Henriques-Normark B

Article: LANCET DIGITAL HEALTH. 2023;5(9):e582-e593

Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium

Shaw D; Abad R; Amin-Chowdhury Z; Bautista A; Bennett D; Broughton K; Cao B; Casanova C; Choi EH; Chu Y-W; Claus H; Coelho J; Corcoran M; Cottrell S; Cunney R; Cuypers L; Dalby T; Davies H; de Gouveia L; Deghmane A-E; Demczuk W; Desmet S; Domenech M; Drew R; du Plessis M; Duarte C; Erlendsdottir H; Fry NK; Fuursted K; Hale T; Henares D; Henriques-Normark B; Hilty M; Hoffmann S; Humphreys H; Ip M; Jacobsson S; Johnson C; Johnston J; Jolley KA; Kawabata A; Kozakova J; Kristinsson KG; Krizova P; Kuch A; Ladhani S; Lam T-T; Leon ME; Lindholm L; Litt D; Maiden MCJ; Martin I; Martiny D; Mattheus W; Mccarthy N; Meehan M; Meiring S; Moelling P; Morfeldt E; Morgan J; Mulhall R; Munoz-Almagro C; Murdoch D; Murphy J; Musilek M; Mzabi A; Novakova L; Oftadeh S; Perez-Arguello A; Perez-Vazquez M; Perrin M; Perry M; Prevost B; Roberts M; Rokney A; Ron M; Sanabria OM; Scott KJ; Sheppard C; Siira L; Sintchenko V; Skoczynska A; Sloan M; Slotved H-C; Smith AJ; Steens A; Taha M-K; Toropainen M; Tzanakaki G; Vainio A; van der Linden MPG; van Sorge NM; Varon E; Vohrnova S; von Gottberg A; Yuste J; Zanella R; Zhou F; Brueggemann ABAlla författare

Article: NATURE COMMUNICATIONS. 2023;14(1):3170

The divisome but not the elongasome organizes capsule synthesis in Streptococcus pneumoniae

Nakamoto R; Bamyaci S; Blomqvist K; Normark S; Henriques-Normark B; Sham L-T

Article: CHEMICAL ENGINEERING JOURNAL. 2023;454:139971

Highly durable photocatalytic titanium suboxide-polymer nanocomposite films with visible light-triggered antibiofilm activity

Bletsa E; Merkl P; Thersleff T; Normark S; Henriques-Normark B; Sotiriou GA

Article: CURRENT OPINION IN CHEMICAL ENGINEERING. 2022;38:100872

Inorganic nanoparticle engineering against bacterial infections

Tsikourkitoudi V; Henriques-Normark B; Sotiriou GA

Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;198(6):1023-1031

The human cathelicidin hCAP-18 in serum of children with haemato-oncological diseases

Jackmann N; Englund S; Frisk P; Makitie O; Utriainen P; Mortberg A; Henriques-Normark B; Putsep K; Harila-Saari A

Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):350-364

Bacterial meningitis: Aetiology, risk factors, disease trends and severe sequelae during 50 years in Sweden

Block N; Naucler P; Wagner P; Morfeldt E; Henriques-Normark B

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(23):e2122386119

Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA

Narciso AR; Iovino F; Thorsdottir S; Mellroth P; Codemo M; Spoerry C; Righetti F; Muschiol S; Normark S; Nannapaneni P; Henriques-Normark B

Article: CLINICAL INFECTIOUS DISEASES. 2022;74(8):1338-1349

Chronic Disease and Immunosuppression Increase the Risk for Nonvaccine Serotype Pneumococcal Disease: A Nationwide Population-based Study

Naucler P; Galanis I; Petropoulos A; Granath F; Morfeldt E; Ortqvist A; Henriques-Normark B

Article: ONCOGENE. 2022;41(15):2173-2186

Enterobacteria impair host p53 tumor suppressor activity through mRNA destabilization

Aschtgen M-S; Fragkoulis K; Sanz G; Normark S; Selivanova G; Henriques-Normark B; Peuget S

Article: EMERGING INFECTIOUS DISEASES. 2022;28(1):137-138

Serotype Replacement after Introduction of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccines in 10 Countries, Europe

Hanquet G; Krizova P; Dalby T; Ladhani SN; Nuorti JP; Danis K; Mereckiene J; Knol MJ; Winje BA; Ciruela P; de Miguel S; Eugenia Portillo M; MacDonald L; Morfeldt E; Kozakova J; Valentiner-Branth P; Fry NK; Rinta-Kokko H; Varon E; Corcoran M; van der Ende A; Vestrheim DF; Munoz-Almagro C; Sanz J-C; Castilla J; Smith A; Henriques-Normark B; Colzani E; Pastore-Celentano L; Savulescu CAlla författare

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(47):e2108244118

THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates

Reithuber E; Wixe T; Ludwig KC; Muller A; Uvell H; Grein F; Lindgren AEG; Muschiol S; Nannapaneni P; Eriksson A; Schneider T; Normark S; Henriques-Normark B; Almqvist F; Mellroth P

Article: JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE. 2021;25:5-7

Antimicrobial resistance research in a post-pandemic world: Insights on antimicrobial resistance research in the COVID-19 pandemic

Rodriguez-Bano J; Rossolini GM; Schultsz C; Tacconelli E; Murthy S; Ohmagari N; Holmes A; Bachmann T; Goossens H; Canton R; Roberts AP; Henriques-Normark B; Clancy CJ; Huttner B; Fagerstedt P; Lahiri S; Kaushic C; Hoffman SJ; Warren M; Zoubiane G; Essack S; Laxminarayan R; Plant L

Article: LANCET DIGITAL HEALTH. 2021;3(6):e360-e370

Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data

Brueggemann AB; van Rensburg MJJ; Shaw D; McCarthy ND; Jolley KA; Maiden MCJ; van der Linden MPG; Amin-Chowdhury Z; Bennett DE; Borrow R; Brandileone M-CC; Broughton K; Campbell R; Cao B; Casanova C; Choi EH; Chu YW; Clark SA; Claus H; Coelho J; Corcoran M; Cottrell S; Cunney RJ; Dalby T; Davies H; de Gouveia L; Deghmane A-E; Demczuk W; Desmet S; Drew RJ; du Plessis M; Erlendsdottir H; Fry NK; Fuursted K; Gray SJ; Henriques-Normark B; Hale T; Hilty M; Hoffmann S; Humphreys H; Ip M; Jacobsson S; Johnston J; Kozakova J; Kristinsson KG; Krizova P; Kuch A; Ladhani SN; Lam T-T; Lebedova V; Lindholm L; Litt DJ; Martin I; Martiny D; Mattheus W; McElligott M; Meehan M; Meiring S; Molling P; Morfeldt E; Morgan J; Mulhall RM; Munoz-Almagro C; Murdoch DR; Murphy J; Musilek M; Mzabi A; Perez-Arguello A; Perrin M; Perry M; Redin A; Roberts R; Roberts M; Rokney A; Ron M; Scott KJ; Sheppard CL; Siira L; Skoczynska A; Sloan M; Slotved H-C; Smith AJ; Song JY; Taha M-K; Toropainen M; Tsang D; Vainio A; van Sorge NM; Varon E; Vlach J; Vogel U; Vohrnova S; von Gottberg A; Zanella RC; Zhou FAlla författare

Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2021;99(6):817-829

Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infections

Lindenberg M; Almeida L; Dhillon-LaBrooy A; Siegel E; Henriques-Normark B; Sparwasser T

Article: PLOS PATHOGENS. 2021;17(4):e1009513

RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion

Eichner H; Karlsson J; Spelmink L; Pathak A; Sham L-T; Henriques-Normark B; Loh E

Article: PLOS PATHOGENS. 2021;17(3):e1009432

Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin

Tabusi M; Thorsdottir S; Lysandrou M; Narciso AR; Minoia M; Srambickal CV; Widengren J; Henriques-Normark B; Iovino F

Article: BIOSENSORS & BIOELECTRONICS. 2021;171:112732

Biofilm interfacial acidity evaluation by pH-Responsive luminescent nanoparticle films

Merkl P; Aschtgen M-S; Henriques-Normark B; Sotiriou GA

Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2021;11:808601

The Role of Minor Pilins in Assembly and Function of the Competence Pilus of Streptococcus pneumoniae

Oliveira V; Aschtgen M-S; van Erp A; Henriques-Normark B; Muschiol S

Article: MBIO. 2020;11(6):e03027-e03020

The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism

Reithuber E; Nannapaneni P; Rzhepishevska O; Lindgren AEG; Ilchenko O; Normark S; Almqvist F; Henriques-Normark B; Mellroth P

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(49):31386-31397

Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways

Sender V; Hentrich K; Pathak A; Ler ATQ; Embaie BT; Lundstrom SL; Gaetani M; Bergstrand J; Nakamoto R; Sham L-T; Widengren J; Normark S; Henriques-Normark B

Article: EMBO MOLECULAR MEDICINE. 2020;12(11):e12695

Mannose receptor-derived peptides neutralize pore-forming toxins and reduce inflammation and development of pneumococcal disease

Subramanian K; Iovino F; Tsikourkitoudi V; Merkl P; Ahmed S; Berry SB; Aschtgen M-S; Svensson M; Bergman P; Sotiriou GA; Henriques-Normark B

Article: MBIO. 2020;11(5):e01774-e01720

Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa

Vidaillac C; Yong VFL; Aschtgen M-S; Qu J; Yang S; Xu G; Seng ZJ; Brown AC; Ali MK; Jaggi TK; Sankaran J; Foo YH; Righetti F; Nedumaran AM; Mac Aogain M; Roizman D; Richard J-A; Rogers TR; Toyofuku M; Luo D; Loh E; Wohland T; Czarny B; Horvat JC; Hansbro PM; Yang L; Li L; Normark S; Normark BH; Chotirmall SH

Article: CHEMICAL COMMUNICATIONS. 2020;56(51):6989-6992

Silica-coated phosphorescent nanoprobes for selective cell targeting and dynamic bioimaging of pathogen-host cell interactions

Iovino F; Merkl P; Spyrogianni A; Henriques-Normark B; Sotiriou GA

Article: EMBO JOURNAL. 2020;39(9):e103852

Grad-seq in a Gram-positive bacterium reveals exonucleolytic sRNA activation in competence control

Hoer J; Garriss G; Di Giorgio S; Hack L-M; Vanselow JT; Foerstner KU; Schlosser A; Henriques-Normark B; Vogel J

Article: MOLECULES. 2020;25(7):1747

Flame-Made Calcium Phosphate Nanoparticles with High Drug Loading for Delivery of Biologics

Tsikourkitoudi V; Karlsson J; Merkl P; Loh E; Henriques-Normark B; Sotiriou GA

Article: CELL HOST & MICROBE. 2020;27(4):544-555.e3

Proton Motive Force Disruptors Block Bacterial Competence and Horizontal Gene Transfer

Domenech A; Brochado AR; Sender V; Hentrich K; Henriques-Normark B; Typas A; Veening J-W

Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2020;58(4):e01993-e01919

Reduced In Vitro Susceptibility of Streptococcus pyogenes to β-Lactam Antibiotics Associated with Mutations in the pbp2x Gene Is Geographically Widespread

Musser JM; Beres SB; Zhu L; Olsen RJ; Vuopio J; Hyyrylainen H-L; Grondahl-Yli-Hannuksela K; Kristinsson KG; Darenberg J; Henriques-Normark B; Hoffmann S; Caugant DA; Smith AJ; Lindsay DSJ; Boragine DM; Palzkill T

Article: SCIENTIFIC REPORTS. 2020;10(1):3670

Gradient acoustic focusing of sub-micron particles for separation of bacteria from blood lysate

Van Assche D; Reithuber E; Qiu W; Laurell T; Henriques-Normark B; Mellroth P; Ohlsson P; Augustsson P

Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(6):689-701

The changing epidemiology of community-acquired pneumonia: nationwide register-based study in Sweden

Naucler P; Henriques-Normark B; Hedlund J; Galanis I; Granath F; Ortqvist A

Article: MBIO. 2019;10(3):e01286-e01219

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae

Garriss G; Nannapaneni P; Simoes AS; Browall S; Subramanian K; Sa-Leao R; Goossens H; de Lencastre H; Henriques-Normark B

Article: BMC INFECTIOUS DISEASES. 2019;19(1):409

Serotype and molecular diversity of nasopharyngeal Streptococcus pneumoniae isolates from children before and after vaccination with the ten-valent pneumococcal conjugate vaccine (PCV10) in Ethiopia

Sime WT; Aseffa A; Woldeamanuel Y; Brovall S; Morfeldt E; Henriques-Normark B

Article: BIOSENSORS & BIOELECTRONICS. 2019;132:286-293

Luminescent CeO₂:Eu³⁺ nanocrystals for robust in situ H₂O₂ real-time detection in bacterial cell cultures

Henning DF; Merkl P; Yun C; Iovino F; Xie L; Mouzourakis E; Moularas C; Deligiannakis Y; Henriques-Normark B; Leifer K; Sotiriou GA

Article: THORAX. 2019;74(5):473-482

Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: implications for adult vaccination

Hanquet G; Krizova P; Valentiner-Branth P; Ladhani SN; Nuorti JP; Lepoutre A; Mereckiene J; Knol M; Winje BA; Ciruela P; Ordobas M; Guevara M; McDonald E; Morfeldt E; Kozakova J; Slotved H-C; Fry NK; Rinta-Kokko H; Varon E; Corcoran M; van der Ende A; Vestrheim DF; Munoz-Almagro C; Latasa P; Castilla J; Smith A; Henriques-Normark B; Whittaker R; Celentano LP; Savulescu C

Article: MICROBIOLOGY SPECTRUM. 2019;7(1):10.1128/microbiolspec.psi

Gram-Positive Type IV Pili and Competence

Muschiol S; Aschtgen M-S; Nannapaneni P; Henriques-Normarkt B

Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:173-181

In Vivo Mouse Models to Study Pneumococcal Host Interaction and Invasive Pneumococcal Disease.

Iovino F; Sender V; Henriques-Normark B

Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:53-59

High-Resolution and Super-Resolution Immunofluorescent Microscopy Ex Vivo to Study Pneumococcal Interactions with the Host.

Iovino F; Henriques-Normark B

Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:35-39

Immunofluorescent Staining and High-Resolution Microscopy to Study the Pneumococcal Cell.

Iovino F; Henriques-Normark B

Article: NATURE MICROBIOLOGY. 2019;4(1):62-70

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival

Subramanian K; Neill DR; Malak HA; Spelmink L; Khandaker S; Marchiori GDL; Dearing E; Kirby A; Yang M; Achour A; Nilvebrant J; Nygren P-A; Plant L; Kadioglu A; Henriques-Normark B

Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:195-202

IVIS Spectrum CT to Image the Progression of Pneumococcal Infections In Vivo.

Sierakowiak A; Henriques-Normark B; Iovino F

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(12):1975-1988

Eosinophilia and reduced STAT3 signaling affect neutrophil cell death in autosomal-dominant Hyper-IgE syndrome

Farmand S; Kremer B; Haeffner M; Puetsep K; Bergman P; Sundin M; Ritterbusch H; Seidl M; Follo M; Henneke P; Henriques-Normark B

Article: CLINICAL MICROBIOLOGY AND INFECTION. 2018;24(11):1158-1163

Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries

Ieven M; Coenen S; Loens K; Lammens C; Coenjaerts E; Vanderstraeten A; Henriques-Normark B; Crook D; Huygen K; Butler CC; Verheij TJM; Little P; Zlateva K; van Loon A; Claas ECJ; Goossens H

Article: BRITISH JOURNAL OF GENERAL PRACTICE. 2018;68(674):e627-e632

Clinical relevance of bacterial resistance in lower respiratory tract infection in primary care: secondary analysis of a multicentre European trial

Teepe J; Broekhuizen BDL; Goossens H; Hordijk PM; Loens K; Lammens C; Leven M; Little P; Butler CC; Coenen S; Godycki-Cwirko M; Henriques-Normark B; Verheij TJM

Article: NATURE COMMUNICATIONS. 2018;9(1):3398

Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

Pathak A; Bergstrand J; Sender V; Spelmink L; Aschtgen M-S; Muschiol S; Widengren J; Henriques-Normark B

Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):476-484

Receptor Blockade: A Novel Approach to Protect the Brain From Pneumococcal Invasion

Iovino F; Thorsdottir S; Henriques-Normark B

Article: MBIO. 2018;9(2):e00559-e00518

Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses

Codemo M; Muschiol S; Iovino F; Nannapaneni P; Plant L; Wai SN; Henriques-Normark B

Article: ANALYTICA CHIMICA ACTA. 2018;1000:223-231

Separation of pathogenic bacteria by chain length

Beech JP; Ho BD; Garriss G; Oliveira V; Henriques-Normark B; Tegenfeldt JO

Article: ELIFE. 2018;7:e29213

Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood

Toepfner N; Herold C; Otto O; Rosendahl P; Jacobi A; Kraeter M; Staechele J; Menschner L; Herbig M; Ciuffreda L; Ford-Cartwright L; Grzybek M; Coskun U; Reithuber E; Garriss G; Mellroth P; Henriques-Normark B; Tregay N; Suttorp M; Bornhaeuser M; Chilvers ER; Berner R; Guck J

Article: CLINICAL INFECTIOUS DISEASES. 2017;65(11):1780-1789

Comparison of the Impact of Pneumococcal Conjugate Vaccine 10 or Pneumococcal Conjugate Vaccine 13 on Invasive Pneumococcal Disease in Equivalent Populations (Publication with Expression of Concern. See vol. 68, pg. 534, 2019)

Naucler P; Galanis I; Morfeldt E; Darenberg J; Ortqvist A; Henriques-Normark B

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(34):14134-14146

Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae

Muschiol S; Erlendsson S; Aschtgen M-S; Oliveira V; Schmieder P; de Lichtenberg C; Teilum K; Boesen T; Akbey U; Henriques-Normark B

Article: LANCET RESPIRATORY MEDICINE. 2017;5(8):648-656

Effect of high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children in SpIDnet countries: an observational multicentre study

Savulescu C; Krizova P; Lepoutre A; Mereckiene J; Vestrheim DF; Ciruela P; Ordobas M; Guevara M; McDonald E; Morfeldt E; Kozakova J; Varon E; Cotter S; Winje BA; Munoz-Almagro C; Garcia L; Castilla J; Smith A; Henriques-Normark B; Celentano LP; Hanquet G

Article: CELL REPORTS. 2017;20(1):251-263

Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method

Dou D; Hernandez-Neuta I; Wang H; Ostbye H; Qian X; Thiele S; Resa-Infante P; Kouassi NM; Sender V; Hentrich K; Mellroth P; Henriques-Normark B; Gabriel G; Nilsson M; Daniels R

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(6):1619-1630

pIgR and PEC AM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Iovino F; Engelen-Lee J-Y; Brouwer M; van de Beek D; van der Ende A; Seron MV; Mellroth P; Muschiol S; Bergstrand J; Widengren J; Henriques-Normark B

Article: VACCINE. 2017;35(20):2654-2660

The Pneumocell-study: Vaccination of IgG1-and IgG2-deficient patients with Prevnar13

Zangenah S; Bjorkhem-Bergman L; Norlin A-C; Hansen S; Lindqvist L; Henriques-Normark B; Bergman P

Article: EPIDEMIOLOGY AND INFECTION. 2017;145(6):1203-1209

Coeliac disease and invasive pneumococcal disease: a population-based cohort study

Tjernberg AR; Bonnedahl J; Inghammar M; Egesten A; Kahlmeter G; Naucler P; Henriques-Normark B; Ludvigsson JF

Article: JOURNAL OF INNATE IMMUNITY. 2017;9(4):375-386

Vitamin D Promotes Pneumococoal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils

Subramanian K; Bergman P; Henriques-Normark B

Article: INFECTION AND IMMUNITY. 2016;84(12):3445-3457

Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation

Sharma-Chawla N; Sender V; Kershaw O; Gruber AD; Volckmar J; Henriques-Normark B; Stegemann-Koniszewski S; Bruder D

Article: MBIO. 2016;7(5):e01783-e01716

Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

Perez-Gallego M; Torrens G; Castillo-Vera J; Moya B; Zamorano L; Cabot G; Hultenby K; Alberti S; Mellroth P; Henriques-Normark B; Normark S; Oliver A; Juan C

Article: CELL HOST & MICROBE. 2016;20(3):307-317

Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR

Hentrich K; Lofling J; Pathak A; Nizet V; Varki A; Henriques-Normark B

Article: MOLECULAR MICROBIOLOGY. 2016;101(6):954-967

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity

Sandalova T; Lee M; Henriques-Normark B; Hesek D; Mobashery S; Mellroth P; Achour A

Article: MUCOSAL IMMUNOLOGY. 2016;9(5):1288-1302

Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection

Dudek M; Puttur F; Arnold-Schrauf C; Kuehl AA; Holzmann B; Henriques-Normark B; Berod L; Sparwasser T

Article: SCIENTIFIC REPORTS. 2016;6:32371

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation

Schulte T; Mikaelsson C; Beaussart A; Kikhney A; Deshmukh M; Wolniak S; Pathak A; Ebel C; Lofling J; Fogolari F; Henriques-Normark B; Dufrene YF; Svergun D; Nygren P-A; Achour A

Article: VACCINE. 2016;34(38):4565-4571

Unaltered pneumococcal carriage prevalence due to expansion of non-vaccine types of low invasive potential 8 years after vaccine introduction in Stockholm, Sweden

Lindstrand A; Galanis I; Darenberg J; Morfeldt E; Naucler P; Blennow M; Alfven T; Henriques-Normark B; Ortqvist A

Article: JOURNAL OF CLINICAL INVESTIGATION. 2016;126(8):2821-2826

Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA

Iovino F; Hammarlof DL; Garriss G; Brovall S; Nannapaneni P; Henriques-Normark B

Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2016;85(2):141-148

lytA-based identification methods can misidentify Streptococcus pneumoniae

Simoes AS; Tavares DA; Rolo D; Ardanuy C; Goossens H; Henriques-Normark B; Linares J; de Lencastre H; Sa-Leao R

Article: EUROPEAN RESPIRATORY JOURNAL. 2016;47(4):1208-1218

Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden

Galanis I; Lindstrand A; Darenberg J; Browall S; Nannapaneni P; Sjostrom K; Morfeldt E; Naucler P; Blennow M; Ortqvist A; Henriques-Normark B

Article: INFECTION AND IMMUNITY. 2016;84(4):894-905

Variation in Inflammatory Response during Pneumococcal Infection Is Influenced by Host-Pathogen Interactions but Associated with Animal Survival

Jonczyk MS; Escudero L; Sylvius N; Norman M; Henriques-Normark B; Andrew PW

Article: MBIO. 2016;7(2):e00168-e00116

Toll-Like Receptor 3/TRIF-Dependent IL-12p70 Secretion Mediated by Streptococcus pneumoniae RNA and Its Priming by Influenza A Virus Coinfection in Human Dendritic Cells

Spelmink L; Sender V; Hentrich K; Kuri T; Plant L; Henriques-Normark B

Article: PLOS ONE. 2016;11(11):e0166018

Pneumococcal Carriage in Children under Five Years in Uganda-Will Present Pneumococcal Conjugate Vaccines Be Appropriate?

Lindstrand A; Kalyango J; Alfven T; Darenberg J; Kadobera D; Bwanga F; Peterson S; Henriques-Normark B; Kallander K

Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2016;6:158

N-acetylglucosamine-Mediated Expression of nagA and nagB in Streptococcus pneumoniae

Afzal M; Shafeeq S; Manzoor I; Henriques-Normark B; Kuipers OP

Article: PLOS ONE. 2016;11(8):e0160734

Cinobufagin Modulates Human Innate Immune Responses and Triggers Antibacterial Activity

Xie S; Spelmink L; Codemo M; Subramanian K; Putsep K; Henriques-Normark B; Olliver M

Article: PLOS PATHOGENS. 2015;11(10):e1005206

BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAM^low CD11b^high Skin Dendritic cells to Draining Lymph Node During CD4+T-Cell Priming

Bollampalli VP; Yamashiro LH; Feng X; Bierschenk D; Gao Y; Blom H; Henriques-Normark B; Nylen S; Rothfuchs AG

Article: THORAX. 2015;70(9):847-853

Respiratory viruses associated with community-acquired pneumonia in children: matched case-control study

Rhedin S; Lindstrand A; Hjelmgren A; Ryd-Rinder M; Ohrmalm L; Tolfvenstam T; Ortqvist A; Rotzen-Ostlund M; Zweygberg-Wirgart B; Henriques-Normark B; Broliden K; Naucler P

Article: GENOMICS DATA. 2015;4:57-59

Transcriptional profiling of UlaR-regulated genes in Streptococcus pneumoniae

Shafeeq S; Afzal M; Henriques-Normark B; Kuipers OP

Article: BIOESSAYS. 2015;37(4):426-435

Uptake of extracellular DNA: Competence induced pili in natural transformation of Streptococcus pneumoniae

Muschiol S; Balaban M; Normark S; Henriques-Normark B

Article: MICROBIOLOGY-SGM. 2015;161(Pt 1):41-49

UlaR activates expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid

Afzal M; Shafeeq S; Henriques-Normark B; Kuipers OP

Article: BMC INFECTIOUS DISEASES. 2014;14:3859

Prevalence of community-acquired bacteraemia in Guinea-Bissau: an observational study

Isendahl J; Manjuba C; Rodrigues A; Xu W; Henriques-Normark B; Giske CG; Naucler P

Article: PEDIATRICS. 2014;134(6):e1528-e1536

Sinusitis and Pneumonia Hospitalization After Introduction of Pneumococcal Conjugate Vaccine

Lindstrand A; Bennet R; Galanis I; Blennow M; Ask LS; Dennison SH; Rinder MR; Eriksson M; Henriques-Normark B; Ortqvist A; Alfven T

Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(6):1646-1657

Clinical manifestations of invasive pneumococcal disease by vaccine and non-vaccine types

Browall S; Backhaus E; Naucler P; Galanis I; Sjostrom K; Karlsson D; Berg S; Luthander J; Eriksson M; Spindler C; Ejdeback M; Trollfors B; Darenberg J; Kalin M; Ortqvist A; Andersson R; Henriques-Normark B

Article: EPIDEMIOLOGY AND INFECTION. 2014;142(11):2251-2260

Human isolates of Listeria monocytogenes in Sweden during half a century (1958-2010)

Lopez-Valladares G; Tham W; Parihar VS; Helmersson S; Andersson B; Ivarsson S; Johansson C; Ringberg H; Tjernberg I; Henriques-Normark B; Danielsson-Tham M-L

Article: CLINICAL INFECTIOUS DISEASES. 2014;59(6):851-857

Clinical Efficacy of Polyspecific Intravenous Immunoglobulin Therapy in Patients With Streptococcal Toxic Shock Syndrome: A Comparative Observational Study

Linner A; Darenberg J; Sjolin J; Henriques-Normark B; Norrby-Teglund A

Article: JOURNAL OF INFECTIOUS DISEASES. 2014;210(1):4-13

Emergence of Hypervirulent Mutants Resistant to Early Clearance During Systemic Serotype 1 Pneumococcal Infection in Mice and Humans

Syk A; Norman M; Fernebro J; Gallotta M; Farmand S; Sandgren A; Normark S; Henriques-Normark B

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(17):E1768-E1776

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

Nasser W; Beres SB; Olsen RJ; Dean MA; Rice KA; Long W; Kristinsson KG; Gottfredsson M; Vuopio J; Raisanen K; Caugant DA; Steinbakk M; Low DE; McGeer A; Darenberg J; Henriques-Normark B; Van Beneden CA; Hoffmann S; Musser JM

Article: PEDIATRICS. 2014;133(3):e538-e545

Clinical Utility of PCR for Common Viruses in Acute Respiratory Illness

Rhedin S; Lindstrand A; Rotzen-Ostlund M; Tolfvenstam T; Ohrmalm L; Rinder MR; Zweygberg-Wirgart B; Ortqvist A; Henriques-Normark B; Broliden K; Naucler P

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(7):E758-E765

Secretion of a pneumococcal type II secretion system pilus correlates with DNA uptake during transformation

Balaban M; Battig P; Muschiol S; Tirier SM; Wartha F; Normark S; Henriques-Normark B

Article: MBIO. 2014;5(1):e01120-e01113

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

Mellroth P; Sandalova T; Kikhney A; Vilaplana F; Hesek D; Lee M; Mobashery S; Normark S; Svergun D; Henriques-Normark B; Achour A

Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2014;42(2):345-353

Adult zebrafish model for pneumococcal pathogenesis

Saralahti A; Piippo H; Parikka M; Henriques-Normark B; Ramet M; Rounioja S

Article: JOURNAL OF INFECTIOUS DISEASES. 2014;209(3):377-388

Intraclonal Variations Among Streptococcus pneumoniae Isolates Influence the Likelihood of Invasive Disease in Children

Browall S; Norman M; Tangrot J; Galanis I; Sjostrom K; Dagerhamn J; Hellberg C; Pathak A; Spadafina T; Sandgren A; Battig P; Franzen O; Andersson B; Ortqvist A; Normark S; Henriques-Normark B

Article: OPEN BIOLOGY. 2014;4(1):130090

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold

Schulte T; Lofling J; Mikaelsson C; Kikhney A; Hentrich K; Diamante A; Ebel C; Normark S; Svergun D; Henriques-Normark B; Achour A

Article: BMJ OPEN RESPIRATORY RESEARCH. 2014;1(1):e000038

Improvement of CRB-65 as a prognostic tool in adult patients with community-acquired pneumonia

Dwyer R; Hedlund J; Henriques-Normark B; Kalin M

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(50):20230-20235

Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis

Kandaswamy K; Liew TH; Wang CY; Huston-Warren E; Meyer-Hoffert U; Hultenby K; Schroeder JM; Caparon MG; Normark S; Henriques-Normark B; Hultgren SJ; Kline KA

Article: CLINICAL MICROBIOLOGY AND INFECTION. 2013;19(12):E559-E567

Oral bacterial community dynamics in paediatric patients with malignancies in relation to chemotherapy-related oral mucositis: a prospective study

Ye Y; Carlsson G; Agholme MB; Wilson JAL; Roos A; Henriques-Normark B; Engstrand L; Modeer T; Putsep K

Article: JOURNAL OF INFECTIOUS DISEASES. 2013;208(9):1474-1481

Immunomodulatory Effects of Vitamin D on Innate and Adaptive Immune Responses to Streptococcus pneumoniae

Olliver M; Spelmink L; Hiew J; Meyer-Hoffert U; Henriques-Normark B; Bergman P

Article: JOURNAL OF BACTERIOLOGY. 2013;195(19):4484-4495

Pilin and Sortase Residues Critical for Endocarditis- and BiofilmAssociated Pilus Biogenesis in Enterococcus faecalis

Nielsen HV; Flores-Mireles AL; Kau AL; Kline KA; Pinkner JS; Neiers F; Normark S; Henriques-Normark B; Caparon MG; Hultgren SJ

Article: CELLULAR MICROBIOLOGY. 2013;15(8):1385-1400

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae

Kuri T; Sorensen AS; Thomas S; Hedestam GBK; Normark S; Henriques-Normark B; McInerney GM; Plant L

Article: COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. 2013;3(7):a010215

The Pneumococcus: Epidemiology, Microbiology, and Pathogenesis

Henriques-Normark B; Tuomanen EI

Article: THORAX. 2013;68(6):571-579

Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia

Naucler P; Darenberg J; Morfeldt E; Ortqvist A; Normark BH

Article: EUROSURVEILLANCE. 2013;18(14):20443-13

Increased incidence of invasive group A streptococcal infections in Sweden, January 2012-February 2013

Darenberg J; Henriques-Normark B; Lepp T; Tegmark-Wisell K; Tegnell A; Widgren K

Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2013;45(4):279-284

Low rate of pneumococci non-susceptible to penicillin in healthy Swedish toddlers

Skovbjerg S; Soderstrom A; Hynsjo L; Normark BH; Ekdahl K; Ahren C

Article: JOURNAL OF INNATE IMMUNITY. 2013;5(1):84-96

TLR7 Contributes to the Rapid Progression but Not to the Overall Fatal Outcome of Secondary Pneumococcal Disease following Influenza A Virus Infection

Stegemann-Koniszewski S; Gereke M; Orrskog S; Lienenklaus S; Pasche B; Bader SR; Gruber AD; Akira S; Weiss S; Henriques-Normark B; Bruder D; Gunzer M

Article: PLOS GENETICS. 2013;9(10):e1003868

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection

Croucher NJ; Mitchell AM; Gould KA; Inverarity D; Barquist L; Feltwell T; Fookes MC; Harris SR; Dordel J; Salter SJ; Browall S; Zemlickova H; Parkhill J; Normark S; Henriques-Normark B; Hinds J; Mitchell TJ; Bentley SD

Article: PLOS ONE. 2013;8(5):e64422

Comprehensive Antigen Screening Identifies Moraxella catarrhalis Proteins That Induce Protection in a Mouse Pulmonary Clearance Model

Smidt M; Battig P; Verhaegh SJC; Niebisch A; Hanner M; Selak S; Schueler W; Morfeldt E; Hellberg C; Nagy E; Lundberg U; Hays JP; Meinke A; Henriques-Normark B

Article: MBIO. 2012;4(1):e00535-e00512

Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease

Orrskog S; Rounioja S; Spadafina T; Gallotta M; Norman M; Hentrich K; Falker S; Ygberg-Eriksson S; Hasenberg M; Johansson B; Uotila LM; Gahmberg CG; Barocchi M; Gunzer M; Normark S; Henriques-Normark B

Article: MBIO. 2012;3(4):e00177-e00112

The Metal Ion-Dependent Adhesion Site Motif of the Enterococcus faecalis EbpA Pilin Mediates Pilus Function in Catheter-Associated Urinary Tract Infection

Nielsen HV; Guiton PS; Kline KA; Port GC; Pinkner JS; Neiers F; Normark S; Henriques-Normark B; Caparon MG; Hultgren SJ

Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2012;31(5):849-857

Description of macrolide-resistant and potential virulent clones of Streptococcus pyogenes causing asymptomatic colonization during 2000-2006 in the Lisbon area.

Pires R; Rolo D; Morais A; Brito-Avô A; Johansson C; Henriques-Normark B; Gonçalo-Marques J; Santos-Sanches I

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(14):11018-11029

LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan

Mellroth P; Daniels R; Eberhardt A; Ronnlund D; Blom H; Widengren J; Normark S; Henriques-Normark B

Article: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2012;36(2):342-348

Defense of zebrafish embryos against Streptococcus pneumoniae infection is dependent on the phagocytic activity of leukocytes

Rounioja S; Saralahti A; Rantala L; Parikka M; Henriques-Normark B; Silvennoinen O; Ramet M

Article: EUROSURVEILLANCE. 2011;16(50):20038-11

A case of diphtheria in Sweden, October 2011

Fredlund H; Noren T; Lepp T; Morfeldt E; Normark BH

Article: INFECTION AND IMMUNITY. 2011;79(10):4210-4217

Human Monocytes Promote Th1 and Th17 Responses to Streptococcus pneumoniae

Olliver M; Hiew J; Mellroth P; Henriques-Normark B; Bergman P

Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2011;43(6-7):448-455

Improvement of CRB-65 as a prognostic scoring system in adult patients with bacteraemic pneumococcal pneumonia

Dwyer R; Hedlund J; Darenberg J; Henriques-Normark B; Naucler P; Runesdotter S; Kalin M

Article: MUCOSAL IMMUNOLOGY. 2011;4(3):325-334

Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes

Duerr CU; Salzman NH; Dupont A; Szabo A; Normark BH; Normark S; Locksley RM; Mellroth P; Hornef MW

Article: INFECTION AND IMMUNITY. 2011;79(2):571-580

Identification of a Family of Effectors Secreted by the Type III Secretion System That Are Conserved in Pathogenic Chlamydiae

Muschiol S; Boncompain G; Vromman F; Dehoux P; Normark S; Henriques-Normark B; Subtil A

Article: PLOS ONE. 2011;6(8):e24394

Studies on the Antibacterial Effects of Statins - In Vitro and In Vivo

Bergman P; Linde C; Putsep K; Pohanka A; Normark S; Henriques-Normark B; Andersson J; Bjorkhem-Bergman L

Article: PLOS ONE. 2011;6(12):e29316

Impaired Release of Antimicrobial Peptides into Nasal Fluid of Hyper-IgE and CVID Patients

Cederlund A; Olliver M; Rekha RS; Lindh M; Lindbom L; Normark S; Henriques-Normark B; Andersson J; Agerberth B; Bergman P

Article: PLOS ONE. 2011;6(10):e24581

Effects of Streptococcus pneumoniae Strain Background on Complement Resistance

Hyams C; Opel S; Hanage W; Yuste J; Bax K; Henriques-Normark B; Spratt BG; Brown JS

Article: JOURNAL OF INFECTIOUS DISEASES. 2010;202(8):1287-1295

Influenza Enhances Susceptibility to Natural Acquisition of and Disease due to Streptococcus pneumoniae in Ferrets

McCullers JA; McAuley JL; Browall S; Iverson AR; Boyd KL; Normark BH

Article: INFECTION AND IMMUNITY. 2010;78(5):1943-1951

Characterization of a Novel Murine Model of Staphylococcus saprophyticus Urinary Tract Infection Reveals Roles for Ssp and SdrI in Virulence

Kline KA; Ingersoll MA; Nielsen HV; Sakinc T; Henriques-Normark B; Gatermann S; Caparon MG; Hultgren SJ

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(5):3300-3309

Disulfide Bond Formation and Cysteine Exclusion in Gram-positive Bacteria

Daniels R; Mellroth P; Bernsel A; Neiers F; Normark S; von Heijne G; Henriques-Normark B

Article: VACCINE. 2009;27:G27-G32

The epidemiology of pneumococcal infections-The Swedish experience

Darenberg J; Normark BH

Article: JOURNAL OF MOLECULAR BIOLOGY. 2009;393(3):704-716

Two Crystal Structures of Pneumococcal Pilus Sortase C Provide Novel Insights into Catalysis and Substrate Specificity

Neiers F; Madhurantakam C; Falker S; Manzano C; Dessen A; Normark S; Henriques-Normark B; Achour A

Article: EMBO MOLECULAR MEDICINE. 2009;1(4):211-222

Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression

Littmann M; Albiger B; Frentzen A; Normark S; Henriques-Normark B; Plant L

Article: JOURNAL OF IMMUNOLOGY. 2009;182(12):7865-7877

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor Cob-Binding Protein in a PspC Allele-Dependent Fashion

Dieudonne-Vatran A; Krentz S; Blom AM; Meri S; Henriques-Normark B; Riesbeck K; Albiger B

Article: FEMS MICROBIOLOGY LETTERS. 2009;296(2):235-240

Resistance to bacitracin in Streptococcus pyogenes from oropharyngeal colonization and noninvasive infections in Portugal was caused by two clones of distinct virulence genotypes.

Pires R; Rolo D; Mato R; Feio de Almeida J; Johansson C; Henriques-Normark B; Morais A; Brito-Avô A; Gonçalo-Marques J; Santos-Sanches I

Article: JOURNAL OF BACTERIOLOGY. 2009;191(10):3237-3247

Mechanism for Sortase Localization and the Role of Sortase Localization in Efficient Pilus Assembly in Enterococcus faecalis

Kline KA; Kau AL; Chen SL; Lim A; Pinkner JS; Rosch J; Nallapareddy SR; Murray BE; Henriques-Normark B; Beatty W; Caparon MG; Hultgren SJ

Article: BMC MICROBIOLOGY. 2009;9:75

Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

Muschiol S; Normark S; Henriques-Normark B; Subtil A

Article: JOURNAL OF INFECTIOUS DISEASES. 2009;199(7):1032-1042

Pattern of Accessory Regions and Invasive Disease Potential in Streptococcus pneumoniae

Blomberg C; Dagerhamn J; Dahlberg S; Browall S; Fernebro J; Albiger B; Morfeldt E; Normark S; Henriques-Normark B

Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2009;47(4):1155-1165

Clinical and Microbiological Characteristics of Severe Streptococcus pyogenes Disease in Europe

Luca-Harari B; Darenberg J; Neal S; Siljander T; Strakova L; Tanna A; Creti R; Ekelund K; Koliou M; Tassios PT; van der Linden M; Straut M; Vuopio-Varkila J; Bouvet A; Efstratiou A; Schalen C; Henriques-Normark B; Jasir A

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2009;65(Pt 1):55-58

Cloning, expression, purification, crystallization and preliminary X-ray analysis of the pilus-associated sortase C from Streptococcus pneumoniae

Neiers F; Madhurantakam C; Falker S; Normark S; Henriques-Normark B; Achour A

Article: PLOS ONE. 2009;4(3):e4840

Increased Susceptibility for Superinfection with Streptococcus pneumoniae during Influenza Virus Infection Is Not Caused by TLR7-Mediated Lymphopenia

Stegemann S; Dahlberg S; Kroeger A; Gereke M; Bruder D; Henriques-Normark B; Gunzer M

Article: FOODBORNE PATHOGENS AND DISEASE. 2008;5(6):755-761

Characterization of Human Invasive Isolates of Listeria monocytogenes in Sweden 1986-2007

Parihar VS; Lopez-Valladares G; Danielsson-Tham M-L; Peiris I; Helmersson S; Unemo M; Andersson B; Arneborn M; Bannerman E; Barbuddhe S; Bille J; Hajdu L; Jacquet C; Johansson C; Lofdahl M; Mollerberg G; Ringberg H; Rocourt J; Tjernberg I; Ursing J; Henriques-Normark B; Tham W

Article: MOLECULAR MICROBIOLOGY. 2008;70(3):595-607

Sortase-mediated assembly and surface topology of adhesive pneumococcal pili

Falker S; Nelson AL; Morfeldt E; Jonas K; Hultenby K; Ries J; Melefors O; Normark S; Henriques-Normark B

Article: VACCINE. 2008;26(43):5541-5546

Effects of a large-scale introduction of the pneumococcal polysaccharide vaccine among elderly persons in Stockholm, Sweden

Spindler C; Hedlund J; Jasir A; Normark BH; Ortqvist A

Article: CELLULAR SIGNALLING. 2008;20(10):1873-1881

Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-α production

Liljeroos M; Vuolteenaho R; Rounioja S; Henriques-Normark B; Hallman M; Ojaniemi M

Article: INFECTION AND IMMUNITY. 2008;76(8):3710-3716

The capsule sensitizes Streptococcus pneumoniae to α-defensins human neutrophil proteins 1 to 3

Beiter K; Wartha F; Hurwitz R; Normark S; Zychlinsky A; Henriques-Normark B

Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2008;46(7):2359-2367

Epidemiology of severe Streptococcus pyogenes disease in Europe

Lamagni TL; Darenberg J; Luca-Harari B; Siljander T; Efstratiou A; Henriques-Normark B; Vuopio-Varkila J; Bouvet A; Creti R; Ekelund K; Koliou M; Reinert RR; Stathi A; Strakova L; Ungureanu V; Schalen C; Jasir A

Article: FASEB JOURNAL. 2008;22(7):2427-2434

Identification of heparin/heparan sulfate interacting protein as a major broad-spectrum antimicrobial protein in lung and small intestine

Meyer-Hoffert U; Hornef M; Henriques-Normark B; Normark S; Andersson M; Putsep K

Article: BMC INFECTIOUS DISEASES. 2008;8:83

An individual-based network model to evaluate interventions for controlling transmission

Karlsson D; Jansson A; Normark BH; Nilsson P

Article: GUT. 2008;57(6):764-771

Secreted enteric antimicrobial activity localises to the mucus surface layer

Meyer-Hoffert U; Hornef MW; Henriques-Normark B; Axelsson L-G; Midtvedt T; Putsep K; Andersson M

Article: SCIENCE SIGNALING. 2008;1(21):pe25

ETosis : A Novel Cell Death Pathway

Wartha F; Henriques-Normark B

Article: BMC MICROBIOLOGY. 2008;8:65

The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease

Fernebro J; Blomberg C; Morfeldt E; Wolf-Watz H; Normark S; Normark BH

Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2008;46(3):863-868

Determination of accessory gene patterns predicts the same relatedness among strains of Streptococcus pneumoniae as sequencing of housekeeping genes does and represents a novel a approach in molecular epidemiology

Dagerhamn J; Blomberg C; Browall S; Sjostrom K; Morfeldt E; Henriques-Normark B

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2008;205(1):117-131

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies

Giefing C; Meinke AL; Hanner M; Henics T; Minh DB; Gelbmann D; Lundberg U; Senn BM; Schunn M; Habel A; Henriques-Normark B; Oetqvist A; Kalin M; von Gabain A; Nagy E

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2008;205(1):183-193

Developmental switch of intestinal antimicrobial peptide expression

Menard S; Foerster V; Lotz M; Guetle D; Duerr CU; Gallo RL; Henriques-Normark B; Puetsep K; Andersson M; Glocker EO; Hornef MW

Article: MOLECULAR MICROBIOLOGY. 2007;66(2):329-340

RrgA is a pilus-associated adhesin in Streptococcus pneumoniae

Nelson AL; Ries J; Bagnoli F; Dahlberg S; Falker S; Rounioja S; Tschop J; Morfeldt E; Ferlenghi I; Hilleringmann M; Holden DW; Rappuoli R; Normark S; Barocchi MA; Henriques-Normark B

Article: CLINICAL INFECTIOUS DISEASES. 2007;45(4):450-458

Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden

Darenberg J; Luca-Harari B; Jasir A; Sandgren A; Pettersson H; Schalen C; Norgren M; Romanus V; Norrby-Teglund A; Normark BH

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(31):12907-12912

Clonal success of piliated penicillin nonsusceptible pneumococci

Sjoestroem K; Blomberg C; Fernebro J; Dagerhamn J; Morfeldt E; Barocchi MA; Browall S; Moschioni M; Andersson M; Henriques F; Albiger B; Rappuoli R; Normark S; Henriques-Normark B

Article: BIOSYSTEMS. 2007;90(1):211-223

Modeling the regulation of the competence-evoking quorum sensing network in Streptococcus pneumoniae

Karlsson D; Karlsson S; Gustafsson E; Normark BH; Nilsson P

Article: CELLULAR MICROBIOLOGY. 2007;9(5):1162-1171

Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps

Wartha F; Beiter K; Albiger B; Fernebro J; Zychlinsky A; Normark S; Henriques-Normark B

Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2007;45(4):1175-1179

International quality assurance study for characterization of Streptococcus pyogenes.

Neal S; Beall B; Ekelund K; Henriques-Normark B; Jasir A; Johnson D; Kaplan E; Lovgren M; Reinert RR; Strep-EURO Study Group; International Streptococcus Reference Laboratories; Efstratiou A

Article: CELLULAR MICROBIOLOGY. 2007;9(3):633-644

Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection

Albiger B; Dahlberg S; Sandgren A; Wartha F; Beiter K; Katsuragi H; Akira S; Normark S; Henriques-Normark B

Article: FEBS LETTERS. 2007;581(4):587-595

Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle

Bailey L; Gylfe A; Sundin C; Muschiol S; Elofsson M; Nordstrom P; Henriques-Normark B; Lugert R; Waldenstrom A; Wolf-Watz H; Bergstrom S

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(39):14566-14571

A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis

Muschiol S; Bailey L; Gylfe A; Sundin C; Hultenby K; Bergstrom S; Elofsson M; Wolf-Watz H; Normark S; Henriques-Normark B

Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2006;25(8):518-521

Addition of a macrolide to a β-lactam in bacteremic pneumococcal pneumonia

Dwyer R; Ortqvist A; Aufwerber E; Henriques Normark B; Marrie TJ; Mufson MA; Torres A; Woodhead MA; Alenius M; Kalin M

Article: CURRENT BIOLOGY. 2006;16(4):401-407

An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps

Beiter K; Wartha F; Albiger B; Normark S; Zychlinsky A; Henriques-Normark B

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(8):2857-2862

A pneumococcal pilus influences virulence and host inflammatory responses

Barocchi MA; Rie J; Zogaj X; Hemsley C; Albiger B; Kanth A; Dahlberg S; Fernebro J; Moschioni M; Masignani V; Hultenby K; Taddei AR; Beiter K; Wartha F; von Euler A; Covacci A; Holden DW; Normark S; Rappuoli R; Henriques-Normark B

Article: CLINICAL INFECTIOUS DISEASES. 2006;42(4):451-459

Clonal and capsular types decide whether pneumococci will act as a primary or opportunistic pathogen

Sjöström K; Spindler C; Ortqvist A; Kalin M; Sandgren A; Kühlmann-Berenzon S; Henriques-Normark B

Article: MICROBIAL DRUG RESISTANCE. 2006;12(1):16-22

Penicillin-resistant pneumococci in Sweden 1997-2003:: Increased multiresistance despite stable prevalence and decreased antibiotic use

Högberg L; Ekdahl K; Sjöström K; Olsson-Liljequist B; Walder M; Melander E; Ringberg H; Normark BH

Article: CELLULAR MICROBIOLOGY. 2005;7(11):1603-1615

Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice

Albiger B; Sandgren A; Katsuragi H; Meyer-Hoffert U; Beiter K; Wartha F; Hornef M; Normark S; Normark BH

Article: MICROBIAL DRUG RESISTANCE. 2005;11(4):360-370

Group A Streptococci from carriage and disease in Portugal: evolution of antimicrobial resistance and T antigenic types during 2000-2002.

Pires R; Rolo D; Gama-Norton L; Morais A; Lito L; Salgado MJ; Johansson C; Möllerberg G; Henriques-Normark B; Gonçalo-Marques J; Santos-Sanches I

Article: CLINICAL INFECTIOUS DISEASES. 2004;38(6):836-842

Differences in potency of intravenous polyspecific immunoglobulin G against streptococcal and staphylococcal superantigens:: Implications for therapy of toxic shock syndrome

Darenberg J; Söderquist B; Normark BH; Norrby-Teglund A

Article: JOURNAL OF INFECTIOUS DISEASES. 2004;189(5):785-796

Effect of clonal and serotype-specific properties on the invasive capacity of Streptococcus pneumoniae

Sandgren A; Sjöström K; Olsson-Liljequist BO; Christensson B; Samuelsson A; Kronvall G; Normark BH

Article: JOURNAL OF INFECTIOUS DISEASES. 2004;189(2):328-338

Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance.

Fernebro J; Andersson I; Sublett J; Morfeldt E; Novak R; Tuomanen E; Normark S; Normark BH

Article: BONE MARROW TRANSPLANTATION. 2004;33(1):79-85

Viridans streptococcal septicaemia in neutropenic patients:: role of proinflammatory cytokines

Ihendyane N; Sparrelid E; Wretlind B; Remberger M; Andersson J; Ljungman P; Ringdén O; Normark BH; Allen U; Low DE; Norrby-Teglund A

Article: JOURNAL OF INFECTIOUS DISEASES. 2003;188(10):1578-1586

Toxin-gene profile heterogeneity among endemic invasive European group A streptococcal isolates

Schmitz FJ; Beyer A; Charpentier E; Normark BH; Schade M; Fluit AC; Hafner D; Novak R

Article: CLINICAL INFECTIOUS DISEASES. 2003;37(9):1189-1193

Group A streptococcal infections in Sweden:: A comparative study of invasive and noninvasive infections and analysis of dominant T28 emm28 isolates

Eriksson BKG; Norgren M; McGregor K; Spratt BG; Normark BH

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2003;198(8):1225-1235

Intracellular recognition of lipopolysaccharide by Toll-like receptor 4 in intestinal epithelial cells

Hornef MW; Normark BH; Vandewalle A; Normark S

Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2003;35(8):452-458

Capsular types and antibiotic susceptibility of invasive Streptococcus pneumoniae among children in Sweden

Hedlund J; Sörberg M; Normark BH; Kronvall G

Article: COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES. 2003;26(1):25-35

RAPD-PCR and PFGE as tools in the investigation of an outbreak of beta-haemolytic Streptococcus group A in a Swedish hospital

González-Rey C; Belin AM; Jörbeck H; Norman M; Krovacek K; Henriques B; Källenius G; Svenson SB

Article: MICROBIAL DRUG RESISTANCE. 2003;9(4):337-344

Clonal analysis of Streptococcus pneumoniae nonsusceptible to penicillin at day-care centers with index cases, in a region with low incidence of resistance:: Emergence of an invasive type 35B clone among carriers

Normark BH; Christensson B; Sandgren A; Noreen B; Sylvan S; Burman LG; Olsson-Liljequist B

Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2001;33(11):848-850

Changes in serotype distribution may hamper efficacy of pneumococcal conjugate vaccines in children

Normark BH; Örtqvist Å; Kalin M; Olsson-Liljequist B; Hedlund J; Svenson SB; Källenius G

Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS, SUPPLEMENT. 2000;89(435):35-39

Epidemiology of pneumococcal infections in Swedish children.

Eriksson M; Henriques B; Ekdahl K

Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2000;32(6):609-614

Invasive group A streptococcal infections in Sweden in 1994 and 1995:: Epidemiology and clinical spectrum

Svensson N; Öberg S; Henriques B; Holm S; Källenius G; Romanus V; Giesecke J

Article: NATURE. 1999;399(6736):590-593

Emergence of vancomycin tolerance in Streptococcus pneumoniae

Novak R; Henriques B; Charpentier E; Normark S; Tuomanen E

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