Bertil Fredholm

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Professor emeritus i farmakologi vid institutionen för fysiologi och farmakologi.

Forskningsbeskrivning

Min forskningen handlar om adenosin och dess receptorer, dess patofysiologiska betydelse och terapeutiska användning. För mer information se forskargruppens webbsida.

Artiklar

Journal article: PURINERGIC SIGNALLING. 2024;20(2):207-208
Some reflections after a long life in science
Fredholm BB
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2023;2023(1)
Adenosine receptors in GtoPdb v.2023.1
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2021;2021(2)
Adenosine receptors in GtoPdb v.2021.2
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Article: PARKINSONISM & RELATED DISORDERS. 2020;80:S3-S6
Why target brain adenosine receptors? A historical perspective
Fredholm BB; Svenningsson P
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2019;2019(4)
Adenosine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Article: SCIENTIFIC REPORTS. 2017;7(1):11458
Acute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growth
Yu NY; Bieder A; Raman A; Mileti E; Katayama S; Einarsdottir E; Fredholm BB; Falk A; Tapia-Paez I; Daub CO; Kere J
Article: PLOS ONE. 2017;12(1):e0170545
Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia
Winerdal M; Urmaliya V; Winerdal ME; Fredholm BB; Winqvist O; Aden U
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(7):e003868
Genetic Abrogation of Adenosine A₃ Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension
Yang T; Zollbrecht C; Winerdal ME; Zhuge Z; Zhang X-M; Terrando N; Checa A; Sallstrom J; Wheelock CE; Winqvist O; Harris RA; Larsson E; Persson AEG; Fredholm BB; Carlstrom M
Article: PURINERGIC SIGNALLING. 2016;12(1):89-101
Adenosine A₁ receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury
Winerdal M; Winerdal ME; Wang Y-Q; Fredholm BB; Winqvist O; Aden U
Article: FRONTIERS IN PHYSIOLOGY. 2015;6:222
In adenosine A_2B knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver
Peleli M; Hezel M; Zollbrecht C; Persson AEG; Lundberg JO; Weitzberg E; Fredholm BB; Carlstrom M
Article: DIABETOLOGIA. 2015;58(7):1610-1620
Abrogation of adenosine A₁ receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses
Yang T; Gao X; Sandberg M; Zollbrecht C; Zhang X-M; Hezel M; Liu M; Peleli M; Lai E-Y; Harris RA; Persson AEG; Fredholm BB; Jansson L; Carlstrom M
Journal article: HYPERTENSION. 2014;64(suppl_1)
Abstract 086: Adenosine A3 Receptors Regulate Oxidative Stress And Inflammatory Responses In A Model Of Hypertension And Renal Disease
Yang T; Hezel M; Peleli M; Zhang X; Terrando N; Fredholm B; Carlström M
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2014;92(3):201-206
Adenosine-a physiological or pathophysiological agent?
Fredholm BB
Article: ACTA PHYSIOLOGICA. 2014;210(3):590-599
Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors
Yang J; Zheng X; Haugen F; Dare E; Lovdahl C; Schulte G; Fredholm BB; Valen G
Article: ACTA PHYSIOLOGICA. 2014;210(2):440-445
Inhibition of sodium-linked glucose reabsorption normalizes diabetes-induced glomerular hyperfiltration in conscious adenosine A₁-receptor deficient mice
Saellstroem J; Eriksson T; Fredholm BB; Persson AEG; Palm F
Journal article: LAKARTIDNINGEN. 2012;109(49-50):2274-2275
[The Nobel Prize to detailed studies of G protein-coupled receptors. This years Nobel Prize in chemistry provides important knowledge--but it might take a while before it can be practically applied].
Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;303(2):E180-E190
Improved blood glucose disposal and altered insulin secretion patterns in adenosine A₁ receptor knockout mice
Yang GK; Fredholm BB; Kieffer TJ; Kwok YN
Article: EUROPEAN REVIEW. 2012;20(3):316-323
How Drugs can Stimulate Psychic Functions - Using Caffeine as an Example
Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2011;301(6):R1669-R1681
Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment
Gao X; Patzak A; Sendeski M; Scheffer PG; Teerlink T; Sallstrom J; Fredholm BB; Persson AEG; Carlstrom M
Article: JOURNAL OF NEUROSCIENCE. 2011;31(45):16327-16335
CX3CL1 Is Neuroprotective in Permanent Focal Cerebral Ischemia in Rodents
Cipriani R; Villa P; Chece G; Lauro C; Paladini A; Micotti E; Perego C; De Simoni M-G; Fredholm BB; Eusebi F; Limatola C
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Alla övriga publikationer

Review: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2019;253:359-381
Adenosine and Sleep.
Lazarus M; Chen J-F; Huang Z-L; Urade Y; Fredholm BB
Editorial: MOLECULAR ASPECTS OF MEDICINE. 2017;55:1-3
Adenosine - from molecular mechanisms to pathophysiology
Sobrevia L; Fredholm BB
Review: MOLECULAR ASPECTS OF MEDICINE. 2017;55:4-8
Pharmacological targeting of adenosine receptor signaling
Peleli M; Fredholm BB; Sobrevia L; Carlstrom M
Review: MOLECULAR ASPECTS OF MEDICINE. 2017;55:20-25
Low, but not high, dose caffeine is a readily available probe for adenosine actions
Fredholm BB; Yang J; Wang Y
Book chapter: COFFEE IN HEALTH AND DISEASE PREVENTION. 2015;p. 831-834
Chapter 91 Adenosine Receptors as the Biochemical Target for Low Doses of Caffeine
Fredholm BB
Conference publication: PURINERGIC SIGNALLING. 2014;10(4):733
Energy homeostasis in mice lacking adenosine receptors
Wang Y; Urmalia V; Bjornholm M; Winerdal M; Carlstrom M; Fredholm BB
Conference publication: HYPERTENSION. 2014;64
Adenosine A3 Receptors Regulate Oxidative Stress And Inflammatory Responses In A Model Of Hypertension And Renal Disease
Yang T; Hezel M; Peleli M; Zhang X; Terrando N; Fredholm B; Carlstrom M
Conference publication: DIABETES. 2014;63:A560
Abrogation of Adenosine A1 Receptor Signaling Improves Metabolic Regulation in Aging and Obesity
Gao X; Sandberg M; Fredholm B; Persson E; Jansson L; Carlstrom M
Conference publication: DIABETES. 2013;62:A480-A481
Adenosine A1 Receptor Deficiency Improves Glucose Metabolism and Attenuates Vasoconstriction of Islet Arterioles to Angiotensin II
Gao X; Sandberg M; Fredholm B; Persson AEG; Jansson L; Carlstrom M
Review: NATURE REVIEWS DRUG DISCOVERY. 2013;12(4):265-286
Adenosine receptors as drug targets - what are the challenges?
Chen J-F; Eltzschig HK; Fredholm BB
Book chapter: ADENOSINE. 2013;p. 3-19
Adenosine and Metabolism—A Brief Historical Note
Fredholm BB
Editorial: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(16):5913-5914
Rethinking the purinergic neuron-glia connection
Fredholm BB
Conference publication: FASEB JOURNAL. 2012;26:690.3
Role of Adenosine A1 Receptors in Regulation of Arteriolar Responses to Adenosine and Angiotensin II
Gao X; Carlstrom M; Fredholm B; Persson E
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S183
Brain adenosine and the actions of caffeine
Fredholm BB
Review: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2011;11(8):973-1011
Adenosine and ATP Receptors in the Brain
Burnstock G; Fredholm BB; Verkhratsky A
Review: PHARMACOLOGICAL REVIEWS. 2011;63(1):1-34
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors-An Update
Fredholm BB; IJzerman AP; Jacobson KA; Linden J; Mueller CE
Review: SLEEP AND BIOLOGICAL RHYTHMS. 2011;9:24-28
Physiological and pathophysiological roles of adenosine
Fredholm BB
Review: ADVANCES IN PHARMACOLOGY. 2011;61:77-94
Adenosine and the regulation of metabolism and body temperature.
Fredholm BB; Johansson S; Wang Y-Q
Published conference paper: JOURNAL OF NEUROIMMUNOLOGY. 2010;224(1-2):85-92
CX₃CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes
Piccinin S; Di Angelantonio S; Piccioni A; Volpini R; Cristalli G; Fredholm BB; Limatola C; Eusebi F; Ragozzino D
Review: CELL DEATH AND DIFFERENTIATION. 2010;17(7):1071-1082
Adenosine signaling and function in glial cells
Boison D; Chen J-F; Fredholm BB
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Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI