Bertil Fredholm

About me
Publications
CV
Public outreach and news

About me

Professor Emeritus of Pharmacology at the Department of Physiology and Pharmacology

Research

My research is about Adenosine and its receptors, pathophysiological significance and therapeutic opportunities. For more information se group page.

Articles

Journal article: PURINERGIC SIGNALLING. 2024;20(2):207-208
Some reflections after a long life in science
Fredholm BB
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2023;2023(1)
Adenosine receptors in GtoPdb v.2023.1
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2021;2021(2)
Adenosine receptors in GtoPdb v.2021.2
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Article: PARKINSONISM & RELATED DISORDERS. 2020;80:S3-S6
Why target brain adenosine receptors? A historical perspective
Fredholm BB; Svenningsson P
Journal article: IUPHAR/BPS GUIDE TO PHARMACOLOGY CITE. 2019;2019(4)
Adenosine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Fredholm BB; Frenguelli BG; Hills R; IJzerman AP; Jacobson KA; Klotz K-N; Linden J; Müller CE; Schwabe U; Stiles GL
Article: SCIENTIFIC REPORTS. 2017;7(1):11458
Acute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growth
Yu NY; Bieder A; Raman A; Mileti E; Katayama S; Einarsdottir E; Fredholm BB; Falk A; Tapia-Paez I; Daub CO; Kere J
Article: PLOS ONE. 2017;12(1):e0170545
Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia
Winerdal M; Urmaliya V; Winerdal ME; Fredholm BB; Winqvist O; Aden U
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(7):e003868
Genetic Abrogation of Adenosine A₃ Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension
Yang T; Zollbrecht C; Winerdal ME; Zhuge Z; Zhang X-M; Terrando N; Checa A; Sallstrom J; Wheelock CE; Winqvist O; Harris RA; Larsson E; Persson AEG; Fredholm BB; Carlstrom M
Article: PURINERGIC SIGNALLING. 2016;12(1):89-101
Adenosine A₁ receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury
Winerdal M; Winerdal ME; Wang Y-Q; Fredholm BB; Winqvist O; Aden U
Article: DIABETOLOGIA. 2015;58(7):1610-1620
Abrogation of adenosine A₁ receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses
Yang T; Gao X; Sandberg M; Zollbrecht C; Zhang X-M; Hezel M; Liu M; Peleli M; Lai E-Y; Harris RA; Persson AEG; Fredholm BB; Jansson L; Carlstrom M
Article: FRONTIERS IN PHYSIOLOGY. 2015;6:222
In adenosine A_2B knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver
Peleli M; Hezel M; Zollbrecht C; Persson AEG; Lundberg JO; Weitzberg E; Fredholm BB; Carlstrom M
Journal article: HYPERTENSION. 2014;64(suppl_1)
Abstract 086: Adenosine A3 Receptors Regulate Oxidative Stress And Inflammatory Responses In A Model Of Hypertension And Renal Disease
Yang T; Hezel M; Peleli M; Zhang X; Terrando N; Fredholm B; Carlström M
Article: ACTA PHYSIOLOGICA. 2014;210(3):590-599
Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors
Yang J; Zheng X; Haugen F; Dare E; Lovdahl C; Schulte G; Fredholm BB; Valen G
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2014;92(3):201-206
Adenosine-a physiological or pathophysiological agent?
Fredholm BB
Article: ACTA PHYSIOLOGICA. 2014;210(2):440-445
Inhibition of sodium-linked glucose reabsorption normalizes diabetes-induced glomerular hyperfiltration in conscious adenosine A₁-receptor deficient mice
Saellstroem J; Eriksson T; Fredholm BB; Persson AEG; Palm F
Article: LAKARTIDNINGEN. 2012;109(49-50):2274-2275
[The Nobel Prize to detailed studies of G protein-coupled receptors. This years Nobel Prize in chemistry provides important knowledge--but it might take a while before it can be practically applied].
Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;303(2):E180-E190
Improved blood glucose disposal and altered insulin secretion patterns in adenosine A₁ receptor knockout mice
Yang GK; Fredholm BB; Kieffer TJ; Kwok YN
Article: EUROPEAN REVIEW. 2012;20(3):316-323
How Drugs can Stimulate Psychic Functions - Using Caffeine as an Example
Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2011;301(6):R1669-R1681
Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment
Gao X; Patzak A; Sendeski M; Scheffer PG; Teerlink T; Sallstrom J; Fredholm BB; Persson AEG; Carlstrom M
Article: JOURNAL OF NEUROSCIENCE. 2011;31(45):16327-16335
CX3CL1 Is Neuroprotective in Permanent Focal Cerebral Ischemia in Rodents
Cipriani R; Villa P; Chece G; Lauro C; Paladini A; Micotti E; Perego C; De Simoni M-G; Fredholm BB; Eusebi F; Limatola C
Article: JOURNAL OF NEUROSCIENCE. 2011;31(27):10067-10075
Arousal Effect of Caffeine Depends on Adenosine A_2A Receptors in the Shell of the Nucleus Accumbens
Lazarus M; Shen H-Y; Cherasse Y; Qu W-M; Huang Z-L; Bass CE; Winsky-Sommerer R; Semba K; Fredholm BB; Boison D; Hayaishi O; Urade Y; Chen J-F
Article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(7):2679-2683
A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors
Masino SA; Li T; Theofilas P; Sandau US; Ruskin DN; Fredholm BB; Geiger JD; Aronica E; Boison D
Article: DIABETES. 2011;60(2):669-679
Links Between Insulin Resistance, Adenosine A_2B Receptors, and Inflammatory Markers in Mice and Humans
Figler RA; Wang G; Srinivasan S; Jung DY; Zhang Z; Pankow JS; Ravid K; Fredholm B; Hedrick CC; Rich SS; Kim JK; LaNoue KF; Linden J
Article: BRAIN RESEARCH. 2011;1367:310-318
Deletion of adenosine A₁ or A_2A receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease
Xiao D; Cassin JJ; Healy B; Burdett TC; Chen J-F; Fredholm BB; Schwarzschild MA
Article: HANDBOOK OF EXPERIMENTAL PHARMACOLOGY. 2011;(200):1-9
Notes on the history of caffeine use.
Fredholm BB
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2011;336(1):77-86
Involvement of Adenosine Signaling in Controlling the Release of Ghrelin from the Mouse Stomach
Yang GK; Yip L; Fredholm BB; Kieffer TJ; Kwok YN
Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2010;299(5):R1263-R1268
High-protein-induced glomerular hyperfiltration is independent of the tubuloglomerular feedback mechanism and nitric oxide synthases
Sallstrom J; Carlstrom M; Olerud J; Fredholm BB; Kouzmine M; Sandler S; Persson AEG
Article: NEUROSCIENCE. 2010;170(3):923-928
PERIPHERAL ADENOSINE A_2A RECEPTORS ARE INVOLVED IN CARRAGEENAN-INDUCED MECHANICAL HYPERALGESIA IN MICE
Li L; Hao JX; Fredholm BB; Schulte G; Wiesenfeld-Hallin Z; Xu XJ
Article: JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION. 2010;30(5):284-286
International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached?
Kenakin T; Agnati LF; Caron M; Fredholm B; Guidoli D; Kobilka B; Lefkowitz RW; Lohse M; Woods A; Fuxe K
Article: FASEB JOURNAL. 2010;24(7):2325-2333
Adenosine A₁ receptors (A₁Rs) play a critical role in osteoclast formation and function
Kara FM; Chitu V; Sloane J; Axelrod M; Fredholm BB; Stanley ER; Cronstein BN
Article: NEUROPSYCHOPHARMACOLOGY. 2010;35(7):1550-1559
Adenosine A₁ Receptors and Microglial Cells Mediate CX3CL1-Induced Protection of Hippocampal Neurons Against Glu-Induced Death
Lauro C; Cipriani R; Catalano M; Trettel F; Chece G; Brusadin V; Antonilli L; van Rooijen N; Eusebi F; Fredholm BB; Limatola C
Article: ACTA PHYSIOLOGICA. 2010;199(2):211-220
Adenosine A₁ receptors and vascular reactivity
Wang Y; Yang JN; Arner A; Boels PJM; Fredholm BB
Article: ACTA PHYSIOLOGICA. 2010;199(2):221-230
Adenosine A₃ receptors regulate heart rate, motor activity and body temperature
Yang JN; Wang Y; Garcia-Roves PM; Bjornholm M; Fredholm BB
Article: NEUROSCIENCE LETTERS. 2010;473(3):178-181
Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A₁ receptors: Insights using knockout mice
Sawynok J; Reid AR; Fredholm BB
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(2):534-541
Adenosine A₁ Receptors Regulate Bone Resorption in Mice Adenosine A₁ Receptor Blockade or Deletion Increases Bone Density and Prevents Ovariectomy-Induced Bone Loss in Adenosine A₁ Receptor-Knockout Mice
Kara FM; Doty SB; Boskey A; Goldring S; Zaidi M; Fredholm BB; Cronstein BN
Article: AMBIO. 2010;39(Suppl 1):31-35
Fuels for Transportation
Fredholm BB; Norden B
Article: JOURNAL OF NEUROIMMUNOLOGY. 2009;215(1-2):36-42
LTP impairment by fractalkine/CX₃CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A₃R)
Maggi L; Trettel F; Scianni M; Bertollini C; Eusebi F; Fredholm BB; Limatola C
Article: LIFE SCIENCES. 2009;85(11-12):470-476
Absence of adenosine A₁ receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin
Salehi A; Parandeh F; Fredholm BB; Grapengiesser E; Hellman B
Article: PHYSIOLOGICAL GENOMICS. 2009;37(3):199-210
Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A_2A receptor knockout mice with microarray profiling
Yu L; Coelho JE; Zhang X; Fu Y; Tillman A; Karaoz U; Fredholm BB; Weng Z; Chen J-F
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2009;296(4):H1141-H1149
Physiological roles of A₁ and A_2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine
Yang J-N; Chen J-F; Fredholm BB
Article: FREE RADICAL RESEARCH. 2009;43(3):304-311
A₁ and A₃ adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of γ-glutamylcysteine ligase
Conte C; Grottelli S; Prudenzi E; Bellezza I; Fredholm BB; Minelli A
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2009;106(2):631-639
Mice heterozygous for both A₁ and A_2A adenosine receptor genes show similarities to mice given long-term caffeine
Yang J-N; Bjorklund O; Lindstrom-Tornqvist K; Lindgren E; Eriksson TM; Kahlstrom J; Chen J-F; Schwarzschild MA; Tobler I; Fredholm BB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(50):19992-19997
Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A₁ receptors and promotes non-rapid eye movement sleep
Oishi Y; Huang Z-L; Fredholm BB; Urade Y; Hayaishi O
Article: PHYSIOLOGY & BEHAVIOR. 2008;95(5):668-676
Decreased behavioral activation following caffeine, amphetamine and darkness in A₃ adenosine receptor knock-out mice
Bjorklund O; Halldner-Henriksson L; Yang J; Eriksson TM; Jacobson MA; Dare E; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2008;597(1-3):92-101
Adenosine A₁ receptors regulate lipolysis and lipogenesis in mouse adipose tissue - Interactions with insulin
JohanssonA SM; Lindgren E; Yang J-N; Herling AW; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2008;596(1-3):6-13
Adenosine A₁ and A₃ receptors protect astrocytes from hypoxic damage
Bjorklund O; Shang M; Tonazzini I; Dare E; Fredholm BB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(39):15118-15123
Adenosine receptor antagonists alter the stability of human epileptic GABA_A receptors
Roseti C; Martinello K; Fucile S; Piccari V; Mascia A; Di Gennaro G; Quarato PP; Manfredi M; Esposito V; Cantore G; Arcella A; Simonato M; Fredholm BB; Limatola C; Miledi R; Eusebi F
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2008;590(1-3):36-42
Adenosine A_2A receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC
Brand F; Klutz AM; Jacobson KA; Fredholm BB; Schulte G
Article: NEUROSCIENCE LETTERS. 2008;440(2):181-184
Caffeine reverses antinociception by amitriptyline in wild type mice but not in those lacking adenosine A₁ receptors
Sawynok J; Reid AR; Fredholm BB
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2008;122(1):107-113.e7
Adenosine induces airway hyperresponsiveness through activation of A₃ receptors on mast cells
Hua X; Chason KD; Fredholm BB; Deshpande DA; Penn RB; Tilley SL
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(14):5609-5613
Postendocytotic traffic of the galanin R1 receptor:: A lysosomal signal motif on the cytoplasmic terminus
Xia S; Dun X-P; Hu P-S; Kjaer S; Zheng K; Qian Y; Solen C; Xu T; Fredholm B; Hokfelt T; Xu Z-QD
Article: MOLECULAR IMMUNOLOGY. 2008;45(8):2247-2254
Adenosine, through the A₁ receptor, inhibits vesicular MHC class I cross-presentation by resting DC
Chen L; Fredholm BB; Jondal M
Article: BIOCHEMICAL PHARMACOLOGY. 2008;75(4):931-941
Promiscuous coupling and involvement of protein kinase C and extracellular signal-regulated kinase 1/2 in the adenosine A₁ receptor signalling in mammalian spermatozoa (Publication with Expression of Concern. See vol. 212, 2023)
Minelli A; Bellezza F; Collodel G; Fredholm BB
Article: PLOS ONE. 2008;3(12):e3977
Perinatal Caffeine, Acting on Maternal Adenosine A₁ Receptors, Causes Long-Lasting Behavioral Changes in Mouse Offspring
Bjorklund O; Kahlstrom J; Salmi P; Fredholm BB
Article: BIOCHEMICAL PHARMACOLOGY. 2007;74(11):1628-1635
A₁ receptor deficiency causes increased insulin and glucagon secretion in mice
Johansson SM; Salehi A; Sandstroem ME; Westerblad H; Lundquist I; Carlsson P-O; Fredholm BB; Katz A
Article: JOURNAL OF IMMUNOLOGY. 2007;179(11):7431-7438
1,3,7-trimethylxanthine (Caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism
Ohta A; Lukashev D; Jackson EK; Fredholm BB; Sitkovsky M
Article: TOXICOLOGY. 2007;241(3):119-133
The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration
Bjoerklund O; Kahlstroem J; Salmi P; Oegren SO; Vahter M; Chen J-F; Fredholm BB; Dare E
Article: NEURON GLIA BIOLOGY. 2007;3(4):353-366
Adenosine dysfunction in astrogliosis: cause for seizure generation?
Li T; Lan JQ; Fredholm BB; Simon RP; Boison D
Article: PHYSIOLOGY & BEHAVIOR. 2007;92(1-2):15-20
Modulation of glial cell functions by adenosine receptors
Dare E; Schulte G; Karovic O; Hammarberg C; Fredholm BB
Article: ACTA PHYSIOLOGICA. 2007;190(3):253-259
Diabetes-induced hyperfiltration in adenosine A₁-receptor deficient mice lacking the tubuloglomerular feedback mechanism
Sallstrom J; Carlsson P-O; Fredholm BB; Larsson E; Persson AEG; Palm F
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(23):9697-9702
A1 adenosine receptors play an essential role in protecting the embryo against hypoxia
Wendler CC; Amatya S; McClaskey C; Ghatpande S; Fredholm BB; Rivkees SA
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2007;581(2):693-708
G protein-independent neuromodulatory action of adenosine on metabotropic glutamate signalling in mouse cerebellar Purkinje cells
Tabata T; Kawakami D; Hashimoto K; Kassai H; Yoshida T; Hashimotodani Y; Fredholm BB; Sekino Y; Aiba A; Kano M
Article: BIOCHEMICAL PHARMACOLOGY. 2007;73(5):694-708
Toxic effects of cobalt in primary cultures of mouse astrocytes -: Similarities with hypoxia and role of HIF-1α
Karovic O; Tonazzini I; Rebola N; Edstrom E; Lovdahl C; Fredholm BB; Dare E
Article: KIDNEY INTERNATIONAL. 2006;70(4):690-698
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction
Lai EY; Patzak A; Steege A; Mrowka R; Brown R; Spielmann N; Persson PB; Fredholm BB; Persson AEG
Article: NEUROPHARMACOLOGY. 2006;51(2):272-282
NMDA depresses glutamatergic synaptic transmission in the striatum through the activation of adenosine A₁ receptors:: Evidence from knockout mice
Schotanus SM; Fredholm BB; Chergui K
Article: NEUROSCIENCE LETTERS. 2006;402(1-2):164-166
Effect of acute and chronic administration of caffeine on pain-like behaviors in rats with partial sciatic nerve injury
Wu W-P; Hao J-X; Fredholm BB; Wiesenfeld-Hallin Z; Xu X-J
Article: EXPERIMENTAL NEUROLOGY. 2006;200(1):184-190
Adenosine A₁ receptors are crucial in keeping an epileptic focus localized
Fedele DE; Li T; Lan JQ; Fredholm BB; Boison D
Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2006;290(5):r1324-r1329
Influence of the adenosine A₁ receptor on blood pressure regulation and renin release
Brown RD; Thorén P; Steege A; Mrowka R; Sällström J; Skott O; Fredholm BB; Persson AEG
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2006;290(4):H1469-H1473
Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning.
Lankford AR; Yang J-N; Rose'Meyer R; French BA; Matherne GP; Fredholm BB; Yang Z
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2006;16(2):129-136
Combination of adenosine A₁ and A_2A receptor blocking agents induces caffeine-like locomotor stimulation in mice
Kuzmin A; Johansson B; Gimenez L; Ögren SO; Fredholm BB
Article: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 2005;82(3):495-505
Differences between A 68930 and SKF 82958 could suggest synergistic roles of D₁ and D₅ receptors
Nergårdh R; Oerther S; Fredholm BB
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2005;289(4):E562-E569
Susceptibility of the developing brain to acute hypoglycemia involving A1 adenosine receptor activation.
Kim M; Yu Z-X; Fredholm BB; Rivkees SA
Article: JOURNAL OF NEUROSCIENCE. 2005;25(37):8432-8438
Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons
Andersson M; Usiello A; Borgkvist A; Pozzi L; Dominguez C; Fienberg AA; Svenningsson P; Fredholm BB; Borrelli E; Greengard P; Fisone G
Article: BIOCHEMICAL PHARMACOLOGY. 2005;70(4):598-605
Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor
Johansson S; Fredholm BB; Hjort C; Morein T; Kull B; Hu PS
Article: NATURE NEUROSCIENCE. 2005;8(7):858-859
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.
Huang Z-L; Qu W-M; Eguchi N; Chen J-F; Schwarzschild MA; Fredholm BB; Urade Y; Hayaishi O
Article: SYNAPSE. 2005;57(1):8-16
Mice lacking the adenosine a, receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly
Giménez-Llort L; Masino SA; Diao LH; Fernández-Teruel A; Tobeña A; Halldner L; Fredholm BB
Article: BEHAVIOURAL BRAIN RESEARCH. 2005;161(1):82-87
Intake inhibition by NPY and CCK-8:: A challenge of the notion of NPY as an "Orexigen"
Ammar AA; Nergårdh R; Fredholm BB; Brodin U; Södersten P
Article: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2005;288(5):G972-G977
Luminal adenosine stimulates chloride secretion through A₁ receptor in mouse jejunum
Ghanem E; Lövdahl C; Daré E; Ledent C; Fredholm BB; Boeynaems JM; Van Driessche W; Beauwens R
Article: JOURNAL OF NEUROSCIENCE. 2005;25(11):2832-2837
The role of extracellular adenosine in regulating mossy fiber synaptic plasticity.
Kukley M; Schwan M; Fredholm BB; Dietrich D
Article: PAIN. 2005;113(3):395-404
Increased nociceptive response in mice lacking the adenosine A₁ receptor
Wu WP; Hao JX; Halldner L; Lövdahl C; DeLander GE; Wiesenfeld-Hallin Z; Fredholm BB; Xu XJ
Article: ACTA PHYSIOLOGICA. 2004;182(2):133-143
Adenosine A₁ receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia
Schulte G; Sommerschild H; Yang J; Tokuno S; Goiny M; Lövdahl C; Johansson B; Fredholm BB; Valen G
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 2004;370(4):270-278
Binding of adenosine receptor ligands to brain of adenosine receptor knock-out mice:: evidence that CGS 21680 binds to A₁ receptors in hippocampus
Halldner L; Lopes LV; Daré E; Lindström K; Johansson B; Ledent C; Cunha RA; Fredholm BB
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2004;20(5):1197-1204
Deletion of the adenosine A₁ receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro
Olsson T; Cronberg T; Rytter A; Asztély F; Fredholm BB; Smith ML; Wieloch T
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2004;497(2):173-180
Neuromuscular blocking agents block carotid body neuronal nicotinic acetylcholine receptors
Jonsson M; Wyon N; Lindahl SGE; Fredholm BB; Eriksson LI
Article: NEUROPHARMACOLOGY. 2004;46(7):1008-1017
The adenosine A₁ receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion:: a study in mice lacking adenosine A₁ and/or A_2A receptors
Halldner L; Ådén U; Dahlberg V; Johansson B; Ledent C; Fredholm BB
Article: JOURNAL OF ANDROLOGY. 2004;25(2):286-292
Involvement of A₁ adenosine receptors in the acquisition of fertilizing capacity
Minelli A; Liguori L; Bellazza I; Mannucci R; Johansson B; Fredholm BB
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2004;141(6):1006-1014
Binding of the prototypical adenosine A_2A receptor agonist CGS 21680 to the cerebral cortex of adenosine A₁ and A_2A receptor knockout mice
Lopes LV; Halldner L; Rebola N; Johansson B; Ledent C; Chen JF; Fredholm BB; Cunha RA
Article: BIOCHEMICAL PHARMACOLOGY. 2004;67(1):129-134
Adenosine A₃ receptor-mediated regulation of p38 and extracellular-regulated kinase ERK1/2 via phosphatidylinositol-3′-kinase
Hammarberg C; Fredholm BB; Schulte G
Article: JOURNAL OF SLEEP RESEARCH. 2003;12(4):283-290
Sleep and its homeostatic regulation in mice lacking the adenosine A₁ receptor
Stenberg D; Litonius E; Halldner L; Johansson B; Fredholm BB; Porkka-Heiskanen T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2003;100(20):11718-11722
A₁ adenosine receptors mediate hypoxia-induced ventriculomegaly
Turner CP; Seli M; Ment L; Stewart W; Yan HL; Johansson B; Fredholm BB; Blackburn M; Rivkees SA
Article: JOURNAL OF NEUROCHEMISTRY. 2003;86(4):1051-1054
Evidence for functional adenosine A₃ receptors in microglia cells
Hammarberg C; Schulte G; Fredholm BB
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;307(1):180-187
Adenosine A_2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells
Lynge J; Schulte G; Nordsborg N; Fredholm BB; Hellsten Y
Article: DRUG NEWS AND PERSPECTIVES. 2003;16(5):283-289
Adenosine receptors as targets for drug development.
Fredholm BB
Article: CELLULAR AND MOLECULAR NEUROBIOLOGY. 2003;23(3):379-400
Synergistic effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization and PKC translocation in DDT1 MF-2 cells.
Fredholm BB; Assender JW; Irenius E; Kodama N; Saito N
Article: STROKE. 2003;34(3):739-744
Aggravated brain damage after hypoxic ischemia in immature adenosine A_2A knockout mice
Ådén U; Halldner L; Lagercrantz H; Dalmau I; Ledent C; Fredholm BB
Article: NEUROSCIENCE. 2003;121(4):907-916
Distribution of antinociceptive adenosine a, receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations
Schulte G; Robertson B; Fredholm BB; Delander GE; Shortland P; Molander C
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 2002;303(1):356-363
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.
Masino SA; Diao L; Illes P; Zahniser NR; Larson GA; Johansson B; Fredholm BB; Dunwiddie TV
Article: NATURE. 2002;418(6899):774-778
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
Lindskog M; Svenningsson P; Pozzi L; Kim Y; Fienberg AA; Bibb JA; Fredholm BB; Nairn AC; Greengard P; Fisone G
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2002;16(3):547-550
Mice lacking the adenosine A₁ receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rat
Giménez-Llort L; Fernández-Teruel A; Escorihuela RM; Fredholm BB; Tobeña A; Pekny M; Johansson B
Article: STROKE. 2002;33(5):1405-1410
MRI evaluation and functional assessment of brain injury after hypoxic ischemia in neonatal mice
Ådén U; Dahlberg V; Fredholm BB; Lai LJ; Chen ZG; Bjelke B
Article: NATURE REVIEWS DRUG DISCOVERY. 2002;1(3):237-238
The role of pharmacology in drug discovery.
Fredholm BB; Fleming WW; Vanhoutte PM; Godfraind T
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 2002;365(2):150-157
Anoxia redistributes adenosine A_2A receptors in PC12 cells and increases receptor-mediated formation of cAMP
Arslan G; Kull B; Fredholm BB
Article: NEUROSCIENCE. 2002;114(3):523-527
Decreased inflammatory pain due to reduced carrageenan-induced inflammation in mice lacking adenosine A₃ receptors
Wu WP; Hao JX; Halldner-Henriksson L; Xu XJ; Jacobson MA; Wiesenfeld-Hallin Z; Fredholm BB
Article: NEUROSCIENCE. 2002;112(2):319-329
Adenosine A_2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A₁ receptor inhibition
Lopes LV; Cunha RA; Kull B; Fredholm BB; Ribeiro JA
Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2001;281(5):R1362-R1367
Abolished tubuloglomerular feedback and increased plasma renin in adenosine A₁ receptor-deficient mice
Brown R; Ollerstam A; Johansson B; Skott O; Gebre-Medhin S; Fredholm B; Persson AEG
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2001;281(5):r1362-r1367
Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice
Brown R; Ollerstam A; Johansson B; Skøtt O; Gebre-Medhin S; Fredholm B; Persson AEG
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2001;426(3):185-192
Adenosine A₁ receptor agonism in the immature rat brain and heart
Ådén U; Leverin AL; Hagberg H; Fredholm BB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(16):9407-9412
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A₁ receptor
Johansson B; Halldner L; Dunwiddie TV; Masino SA; Poelchen W; Giménez-Llort L; Escorihuela RM; Fernández-Teruel A; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Betsholtz C; Herlenius E; Fredholm BB
Article: NEUROREPORT. 2001;12(8):1577-1580
Opposite changes in adenosine A₁ and A_2A receptor mRNA in the rat following sleep deprivation
Basheer R; Halldner L; Alanko L; McCarley RW; Fredholm BB; Porkka-Heiskanen T
Article: BIOCHEMICAL PHARMACOLOGY. 2001;61(4):443-448
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells
Fredholm BB; Irenius E; Kull B; Schulte G
Article: LAKARTIDNINGEN. 2001;98(6):534-539
[Pharmacology at the start of a new millennium. Larger assortment and individual drug dosing are coming].
Fredholm BB; Sjöqvist F
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 2000;21(12):453-456
Research on purines and their receptors comes of age.
Pintor J; Miras-Portugal T; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2000;406(3):345-354
Lack of tolerance to motor stimulant effects of a selective adenosine A_2A receptor antagonist
Halldner L; Lozza G; Lindström K; Fredholm BB
Article: NEUROSCIENCE LETTERS. 2000;292(3):183-186
Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells.
Arslan G; Fredholm BB
Article: MOLECULAR PHARMACOLOGY. 2000;58(4):771-777
Adenosine A_2A receptors are colocalized with and activate G_olf in rat striatum
Kull B; Svenningsson P; Fredholm BB
Article: NEUROPHARMACOLOGY. 2000;39(12):2374-2380
GTP differentially affects antagonist radioligand binding to adenosine A₁ and A_2A receptors in human brain
Kull B; Svenningsson P; Hall H; Fredholm BB
Article: MOLECULAR PHARMACOLOGY. 2000;58(3):477-482
Human adenosine A₁, A_2A, A_2B, and A₃ receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2
Schulte G; Fredholm BB
Article: JOURNAL OF NEUROSCIENCE. 2000;20(16):5949-5957
Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors.
Zahniser NR; Simosky JK; Mayfield RD; Negri CA; Hanania T; Larson GA; Kelly MA; Grandy DK; Rubinstein M; Low MJ; Fredholm BB
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2000;12(8):3026-3032
Differences in the effect of chronic and acute caffeine on self-administration of cocaine in mice
Kuzmin A; Johansson B; Semenova S; Fredholm BB
Article: PEDIATRIC RESEARCH. 2000;48(2):177-183
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain
Ådén U; Herlenius E; Tang LQ; Fredholm BB
Article: BRAIN RESEARCH. 2000;872(1-2):44-53
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats
Berman RF; Fredholm BB; Aden U; O'Connor WT
Article: JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM. 2000;81(1-3):82-86
Nitric oxide interacts with oxygen free radicals to evoke the release of adenosine and adenine nucleotides from rat hippocampal slices.
Broad RM; Fallahi N; Fredholm BB
Article: JOURNAL OF NEUROCHEMISTRY. 2000;75(1):248-257
Dopamine D₁ receptor-induced gene transcription is modulated by DARPP-32
Svenningsson P; Fienberg AA; Allen PB; Le Moine C; Lindskog M; Fisone G; Greengard P; Fredholm BB
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2000;130(2):471-477
Thyrotropin regulates adenosine A(1) receptor expression in rat thyroid FRTL-5 cells.
Vainio M; Fredholm BB; Törnquist K
Article: LAKARTIDNINGEN. 2000;97(17):2046-2048
[The journey from genome structure to cure of diseases is long and winding. Research specialists in molecular biology and physiology should cooperate].
Fredholm BB
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(4):1856-1860
Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D₁, dopamine D₂, and adenosine A_2A receptors
Svenningsson P; Lindskog M; Ledent C; Parmentier M; Greengard P; Fredholm BB; Fisone G
Article: NEUROPHARMACOLOGY. 2000;39(3):482-496
P2Y receptors contribute to ATP-induced increases in intracellular calcium in differentiated but not undifferentiated PC12 cells
Arslan G; Catalin CM; Irenius E; Kull B; Clementi E; Allgaier C; Erlinge D; Fredholm BB
Article: LIFE SCIENCES. 2000;66(8):PL113-PL118
Genetic evidence that cocaine and caffeine stimulate locomotion in mice via different mechanisms
Kuzmin A; Johansson B; Fredholm BB; Ögren SO
Article: NEUROSCIENCE. 2000;98(4):749-757
Co-stimulation of D₁/D₅ and D₂ dopamine receptors leads to an increase in c-fos messenger RNA in cholinergic interneurons and a redistribution of c-fos messenger RNA in striatal projection neurons
Svenningsson P; Fredholm BB; Bloch B; Le Moine C
Article: BIOCHEMICAL PHARMACOLOGY. 1999;58(6):1035-1045
Reciprocal interactions between adenosine A_2A and dopamine D₂ receptors in Chinese hamster ovary cells co-transfected with the two receptors
Kull B; Ferré S; Arslan G; Svenningsson P; Fuxe K; Owman C; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;380(2-3):197-202
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A₁ and A_2A receptors
Fredholm BB; Lindström K
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1999;290(2):535-542
Caffeine, acting on adenosine A₁ receptors, prevents the extinction of cocaine-seeking behavior in mice
Kuzmin A; Johansson B; Zvartau EE; Fredholm BB
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1999;11(6):2182-2186
μ- and δ-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons
Lindskog M; Svenningsson P; Fredholm B; Greengard P; Fisone G
Article: JOURNAL OF NEUROSCIENCE. 1999;19(10):4011-4022
The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions
Svenningsson P; Nomikos GG; Fredholm BB
Article: NEUROCHEMISTRY INTERNATIONAL. 1999;34(3):235-244
Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum:: lack of changes after a neonatal bilateral lesion of the ventral hippocampus
Lillrank SM; Lipska BK; Weinberger DR; Fredholm BB; Fuxe K; Ferré S
Article: NEUROSCIENCE. 1999;89(3):827-837
Opposite tonic modulation of dopamine and adenosine on c-fos gene expression in striatopallidal neurons
Svenningsson P; Fourreau L; Bloch B; Fredholm BB; Gonon F; Le Moine C
Article: BIOCHEMICAL PHARMACOLOGY. 1999;57(1):65-75
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A_2A receptors
Kull B; Arslan G; Nilsson C; Owman C; Lorenzen A; Schwabe U; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1999;359(1):28-32
Signaling via A_2A adenosine receptor in four PC12 cell clones
Arslan G; Kull B; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1999;359(1):7-10
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Ongini E; Dionisotti S; Gessi S; Irenius E; Fredholm BB
Article: FEBS LETTERS. 1998;441(1):97-102
Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K⁺-channel activity in insulin-secreting cells
Köhler M; Norgren S; Berggren PO; Fredholm BB; Larsson O; Rhodes CJ; Herbert TP; Luthman H
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 1998;399(2):229-240
Cellular distribution of adenosine A_2A receptor mRNA in the primate striatum
Svenningsson P; Le Moine C; Aubert I; Burbaud P; Fredholm BB; Bloch B
Article: DRUG AND ALCOHOL DEPENDENCE. 1998;51(1-2):199-206
Caffeine--an atypical drug of dependence.
Daly JW; Fredholm BB
Article: NEUROSCIENCE. 1998;84(1):223-228
Activation of adenosine A_2A and dopamine D₁ receptors stimulates cyclic AMP dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons
Svenningsson P; Lindskog M; Rognoni F; Fredholm BB; Greengard P; Fisone G
Article: BRAIN RESEARCH. 1998;791(1-2):177-185
Age-dependent changes in adenosine receptors are not modified by life-long intermittent alcohol administration
Fredholm BB; Johansson B; Lindström K; Wahlström G
Article: JOURNAL OF NEUROCHEMISTRY. 1998;70(3):1210-1216
[³H]SCH 58261, a selective adenosine A_2A receptor antagonist, is a useful ligand in autoradiographic studies
Fredholm BB; Lindström K; Dionisotti S; Ongini E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(8):4718-4724
Adenosine A₁ receptor-mediated modulation of dopamine D₁ receptors in stably cotransfected fibroblast cells
Ferré S; Torvinen M; Antoniou K; Irenius E; Civelli O; Arenas E; Fredholm BB; Fuxe K
Article: LAKARTIDNINGEN. 1998;95(6):534-535
[Thoughts at the start of a new year. What happens to time?].
Fredholm BB
Article: NEUROPHARMACOLOGY. 1998;37(3):331-337
Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat
Svenningsson P; Nergårdh R; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1997;357(1):1-9
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells
Klotz KN; Hessling J; Hegler J; Owman C; Kull B; Fredholm BB; Lohse MJ
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1997;340(2-3):169-175
Glucose deprivation increases basal and electrically evoked transmitter release from rat striatal slices. Role of NMDA and adenosine A1 receptors.
Jin S; Fredholm BB
Article: LAKARTIDNINGEN. 1997;94(49):4650-4651
[Our genetic differences confirm the idea on equal value of all human beings].
Fredholm B
Article: ACTA PHYSIOLOGICA. 1997;161(4):517-525
Spinal expression of mRNA for immediate early genes in a model of chronic pain
DeLander GE; Schott E; Brodin E; Fredholm BB
Article: ACTA PHYSIOLOGICA. 1997;161(4):509-516
Temporal changes in spinal cord expression of mRNA for substance P, dynorphin and enkephalin in a model of chronic pain
Delander GE; Schött E; Brodin E; Fredholm BB
Article: SYNAPSE. 1997;27(4):322-335
Distribution of adenosine receptors in the postmortem human brain: An extended autoradiographic study
Svenningsson P; Hall H; Sedvall G; Fredholm BB
Article: EXPERIMENTAL EYE RESEARCH. 1997;65(5):595-602
Localization of adenosine receptor messenger RNAs in the rat eye
Kvanta A; Seregard S; Sejersen S; Kull B; Fredholm BB
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1997;9(11):2370-2382
Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle
Chergui K; Svenningsson P; Nomikos GG; Gonon F; Fredholm BB; Svennson TH
Article: LAKARTIDNINGEN. 1997;94(42):3711-3712
[New discoveries on adenosis and prostacyclin. Physiological processes are surveyed in genetic elimination trials].
Fredholm BB
Article: JOURNAL OF NEUROSCIENCE. 1997;17(20):8038-8048
Dopamine-adenosine interactions in the striatum and the globus pallidus: Inhibition of striatopallidal neurons through either D-2A receptors enhances D-2 receptor-mediated effects on c-fos expression
LeMoine C; Svenningsson P; Fredholm BB; Bloch B
Article: LAKARTIDNINGEN. 1997;94(40):3474-3477
[Political control of the universities is contra-productive and hazardous. Free universities are important for democracy].
Fredholm B
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1997;9(10):2135-2141
Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum
Svenningsson P; Georgieva J; Kontny E; Heilig M; Fredholm BB
Article: NEUROSCIENCE. 1997;80(4):1171-1185
Cellular expression of adenosine A(2A) receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas
Svenningsson P; LeMoine C; Kull B; Sunahara R; Bloch B; Fredholm BB
Journal article: PEDIATRIC RESEARCH. 1997;42(3):386
The Effect of Adenosine Receptor Antagonists on Neonatal Cerebral Hypoxia-Ischemia
Bona E; Ådén U; Gilland E; Fredholm BB; Hagberg H
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(7):1269-1276
Electrically-evoked dopamine and acetylcholine release from rat striatal slices perfused without magnesium: regulation by glutamate acting on NMDA receptors.
Jin S; Fredholm BB
Article: NEUROSCIENCE. 1997;79(3):753-764
Antagonism of adenosine A(2A) receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens
Svenningsson P; Nomikos GG; Ongini E; Fredholm BB
Article: BRAIN RESEARCH. 1997;762(1-2):153-164
A(1) and A(2A) adenosine receptors and A(1) mRNA in mouse brain: effect of long-term caffeine treatment
Johansson B; Georgiev V; Lindstrom K; Fredholm BB
Article: ACTA PHYSIOLOGICA. 1997;160(3):207-217
5-Hydroxytryptamine, angiotensin and bradykinin transiently increase intracellular calcium concentrations and PKC-alpha activity, but do not induce mitogenesis in human vascular smooth muscle cells.
Assender JW; Irenius E; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1997;329(2-3):107-113
Adenosine A1 receptors mediate hypoxia-induced inhibition of electrically evoked transmitter release from rat striatal slices.
Jin S; Fredholm BB
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(3):353-360
Characterization of human A(2A) adenosine receptors with the antagonist radioligand [H-3]-SCH 58261
Dionisotti S; Ongini E; Zocchi C; Kull B; Arslan G; Fredholm BB
Article: LAKARTIDNINGEN. 1997;94(19):1787-1788
[New series: action mechanisms of drugs].
Fredholm BB
Article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1997;18(3):79-82
Towards a revised nomenclature for P1 and P2 receptors.
Fredholm BB; Abbracchio MP; Burnstock G; Dubyak GR; Harden TK; Jacobson KA; Schwabe U; Williams M
Article: NUCLEAR MEDICINE AND BIOLOGY. 1997;24(2):187-191
In vivo biodistribution of [N-C-11-methyl]KF 17837 using 3-D-PET: Evaluation as a ligand for the study of adenosine A(2A) receptors
StoneElander S; Thorell JO; Eriksson L; Fredholm BB; Ingvar M
Article: JOURNAL OF MOLECULAR NEUROSCIENCE. 1997;8(1):29-44
On the role of the low-affinity neurotrophin receptor p75(LNTR) in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells
Kontny E; Ciruela F; Svenningsson P; Ibanez CF; Fredholm BB
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1997;280(2):1094-1101
Glucocorticoids regulate the expression of adenosine A(1) but not A(2A) receptors in rat brain
Svenningsson P; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;355(1):48-56
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Jin S; Fredholm BB
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;316(2-3):325-331
Adenosine A(2A) receptors modulate the binding characteristics of dopamine D-2 receptors in stably cotransfected fibroblast cells
Dasgupta S; Ferre S; Kull B; Hedlund PB; Finnman UB; Ahlberg S; Arenas E; Fredholm BB; Fuxe K
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1996;8(12):2447-2458
Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding
Johansson B; Georgiev V; Kuosmanen T; Fredholm BB
Article: DRUG DEVELOPMENT RESEARCH. 1996;39(3-4):450-460
Neuropharmacology of the adenosine A(2A) receptors
Ongini E; Dionisotti S; Morelli M; Ferre S; Svenningsson P; Fuxe K; Fredholm BB
Article: DRUG DEVELOPMENT RESEARCH. 1996;39(3-4):262-268
Adenosine (P1) receptor signalling
Fredholm BB; Arslan C; Kull B; Kontny E; Svenningsson P
Article: DRUG DEVELOPMENT RESEARCH. 1996;39(3-4):461-466
Receptor nomenclature
Fredholm BB; Burnstock G; Harden TK; Spedding M
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;313(3):237-242
Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A(2A) receptors
Zhang Y; Raud J; Hedqvist P; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;354(4):539-541
The selective adenosine A(2A) receptor antagonist SCH 58261 discriminates between two different binding sites for [H-3]-CGS 21680 in the rat brain
Lindstrom K; Ongini E; Fredholm BB
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1996;79(3):120-123
Effects of ethanol and acetate on adenosine production in rat hippocampal slices.
Fredholm BB; Wallman-Johansson A
Article: ACTA PHYSIOLOGICA. 1996;157(4):451-460
Endothelin-1 causes a prolonged protein kinase C activation and acts as a co-mitogen in vascular smooth muscle cells.
Assender JW; Irenius E; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;354(3):262-267
AdenosineA(2A) receptors mediate the inhibitory effect of adenosine on formyl-Met-Leu-Phe-stimulated respiratory burst in neutrophil leucocytes
Fredholm BB; Zhang Y; vanderPloeg I
Article: JOURNAL OF NEUROCHEMISTRY. 1996;67(1):186-193
Release of adenosine from rat hippocampal slices by nitric oxide donors.
Fallahi N; Broad RM; Jin S; Fredholm BB
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1996;8(7):1545-1553
Dopamine D-1 receptor-mediated facilitation of GABAergic neurotransmission in the rat strioentopeduncular pathway and its modulation by adenosine A(1) receptor-mediated mechanisms
Ferre S; OConnor WT; Svenningsson P; Bjorklund L; Lindberg J; Tinner B; Stromberg I; Goldstein M; Ogren SO; Ungerstedt U; Fredholm BB; Fuxe K
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;306(1-3):187-194
Plasma membrane Ca2+ pumping plays a prominent role in adenosine A1 receptor mediated changes in [Ca2+]i in DDT1 MF-2 cells.
Sipma H; Fredholm BB; Den Hertog A; Nelemans A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(10):5161-5165
Oscillations in K-ATP channel activity promote oscillations in cytoplasmic free Ca2+ concentration in the pancreatic beta cell
Larsson O; Kindmark H; Branstrom R; Fredholm B; Berggren PO
Article: BIOCHEMICAL PHARMACOLOGY. 1996;51(7):957-965
Biphasic effect of ATP on neutrophil functions mediated by P-2U and adenosine A(2A) receptors
Zhang Y; Palmblad J; Fredholm BB
Article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1996;277(1):193-197
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
Broad RM; Fredholm BB
Article: IMMUNOLOGY LETTERS. 1996;49(3):197-201
P-2X purinoceptor is not important in thymocyte apoptosis
Jiang SN; Kull B; Fredholm BB; Orrenius S
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;353(3):261-271
Evidence for high affinity binding sites for the adenosine A(2A) receptor agonist [H-3] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A(2A) receptors
Cunha RA; Johansson B; Constantino MD; Sebastiao AM; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1996;353(3):250-260
Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists.
van der Ploeg I; Ahlberg S; Parkinson FE; Olsson RA; Fredholm BB
Article: ADVANCES IN NEUROLOGY. 1996;71:469-474
Caffeine and ischemia - Effects on immediate early genes and adenosine receptors
Fredholm BB; Aden U; Lindstrom K; Bona E; Hagberg H
Article: BRAIN RESEARCH. 1996;35(1-2):183-189
Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801
Svenningsson P; Johansson B; Fredholm BB
Article: LIFE SCIENCES. 1996;58(9):769-776
Adaptive changes in adenosine receptors following long-term treatment with the adenosine receptor agonist R-phenylisopropyl adenosine
Fernandez M; Svenningsson P; Fredholm BB
Article: NEUROPHARMACOLOGY. 1996;35(1):79-89
Adenosine A(1) and A(2A) receptors and nitrobenzylthioinosine-sensitive transporters in gerbil brain: No changes following long-term treatment with the adenosine transport inhibitor propentofylline
Parkinson FE; Johansson B; Lindstrom K; Fredholm BB
Article: LAKARTIDNINGEN. 1995;92(44):4079-4080
[Should coffee be classified as a doping agent? Caffeine is definitely effective when it comes to performance capacity].
Fredholm BB
Article: JOURNAL OF NEUROSCIENCE. 1995;15(11):7612-7624
BIPHASIC CHANGES IN LOCOMOTOR BEHAVIOR AND IN EXPRESSION OF MESSENGER-RNA FOR NGFI-A AND NGFI-B IN RAT STRIATUM FOLLOWING ACUTE CAFFEINE ADMINISTRATION
SVENNINGSSON P; NOMIKOS GG; FREDHOLM BB
Article: PEDIATRIC RESEARCH. 1995;38(3):312-318
THE EFFECT OF LONG-TERM CAFFEINE TREATMENT ON HYPOXIC-ISCHEMIC BRAIN-DAMAGE IN THE NEONATE
BONA E; ADEN U; FREDHOLM BB; HAGBERG H
Article: NEUROSCIENCE LETTERS. 1995;196(1-2):41-44
ADENOSINE A(2A) RECEPTORS STIMULATE ACETYLCHOLINE-RELEASE FROM NERVE-TERMINALS OF THE RAT HIPPOCAMPUS
CUNHA RA; JOHANSSON B; FREDHOLM BB; RIBEIRO JA; SEBASTIAO AM
Article: ACTA PHYSIOLOGICA. 1995;154(1):17-24
EFFECT OF DIFFERENT XANTHINES AND PHOSPHODIESTERASE INHIBITORS ON C-FOS EXPRESSION IN RAT STRIATUM
SVENNINGSSON P; JOHANSSON B; FREDHOLM BB
Article: JOURNAL OF NEUROSCIENCE. 1995;15(5):3583-3593
INCREASED EXPRESSION OF C-JUN, JUNB, AP-1, AND PREPROENKEPHALIN MESSENGER-RNA IN RAT STRIATUM FOLLOWING A SINGLE INJECTION OF CAFFEINE
SVENNINGSSON P; STROM A; JOHANSSON B; FREDHOLM BB
Article: LAKARTIDNINGEN. 1995;92(14):1454-1457
[A new series: growth factors].
Fredholm BB; Heldin CH
Article: NEUROCHEMISTRY INTERNATIONAL. 1995;26(4):387-395
Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices.
Lloyd HG; Fredholm BB
Article: NEUROPHARMACOLOGY. 1995;34(4):393-403
FURTHER CHARACTERIZATION OF THE BINDING OF THE ADENOSINE RECEPTOR AGONIST [H-3] CGS-21680 TO RAT-BRAIN USING AUTORADIOGRAPHY
JOHANSSON B; FREDHOLM BB
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1995;76(4):228-239
Purinoceptors in the nervous system.
Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1995;351(2):194-201
Activation of phospholipase C and phospholipase D by stimulation of adenosine A1, bradykinin or P2U receptors does not correlate well with protein kinase C activation.
Gerwins P; Fredholm BB
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1995;351(2):186-193
Activation of adenosine A1 and bradykinin receptors increases protein kinase C and phospholipase D activity in smooth muscle cells.
Gerwins P; Fredholm BB
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1995;76(2):93-101
Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine.
Fredholm BB
Article: PHYSIOLOGY. 1995;10:122-128
ADENOSINE RECEPTORS IN THE CENTRAL-NERVOUS-SYSTEM
FREDHOLM BB
Journal article: LAKARTIDNINGEN. 1994;91(51-52):4871-4872
[Searching after purpose in a meaningless world].
Fredholm BB
Journal article: UGESKRIFT FOR LAEGER. 1994;156(50):7520-7524
[The 1994 Nobel Prize: discovery and significance of G-proteins].
Fredholm BB; Aperia A
Journal article: BIOCHEMICAL PHARMACOLOGY. 1994;48(11):2043-2047
A(2A) D-2 RECEPTOR INTERACTIONS ARE NOT OBSERVED IN COS-7 CELLS TRANSIENTLY TRANSFECTED WITH DOPAMINE D-2 AND ADENOSINE A(2A) RECEPTOR CDNA
SNAPRUD P; GERWINS P; CARON MG; LIBERT F; PERSSON H; FREDHOLM BB; FUXE K
Journal article: BIOCHEMICAL PHARMACOLOGY. 1994;48(11):2025-2032
PROPENTOFYLLINE ENHANCEMENT OF THE ACTIONS OF ADENOSINE ON NEUTROPHIL LEUKOCYTES
ZHANG Y; FREDHOLM BB
Journal article: NEUROSCIENCE LETTERS. 1994;180(2):91-95
CHANGES IN C-FOS MESSENGER-RNA IN THE NEONATAL RAT-BRAIN FOLLOWING HYPOXIC ISCHEMIA
ADEN U; BONA E; HAGBERG H; FREDHOLM BB
Journal article: LAKARTIDNINGEN. 1994;91(42):3811-3817
[Nature's solution of the communication problem resulted in Nobel Prize. Significance of G-proteins for signal transmission in cells].
Fredholm BB; Aperia A
Journal article: GENERAL PHARMACOLOGY: THE VASCULAR SYSTEM. 1994;25(6):1053-1058
Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia.
Parkinson FE; Rudolphi KA; Fredholm BB
Journal article: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 1994;26(10-11):1227-1236
Modulation of nerve and glial function by adenosine--role in the development of ischemic damage.
Schubert P; Rudolphi KA; Fredholm BB; Nakamura Y
Journal article: NEUROPHARMACOLOGY. 1994;33(9):1039-1048
ROLE OF NMDA, AMPA AND KAINATE RECEPTORS IN MEDIATING GLUTAMATE-INDUCED AND 4-AP-INDUCED DOPAMINE AND ACETYLCHOLINE-RELEASE FROM RAT STRIATAL SLICES
JIN S; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1994;151(4):515-525
Carbachol-induced phosphatidylcholine hydrolysis and choline efflux in rat submandibular gland involves phospholipase D activation and is modulated by protein kinase C and calcium.
Dunér-Engström M; Fredholm BB
Journal article: NEUROCHEMISTRY INTERNATIONAL. 1994;25(1):99-102
Adenosine A2B receptor signalling is altered by stimulation of bradykinin or interleukin receptors in astroglioma cells.
Fredholm BB; Altiok N
Journal article: BRAIN RESEARCH. 1994;649(1-2):208-216
EVIDENCE FOR FUNCTIONALLY IMPORTANT ADENOSINE A(2A) RECEPTORS IN THE RAT HIPPOCAMPUS
CUNHA RA; JOHANSSON B; VANDERPLOEG I; SEBASTIAO AM; RIBEIRO JA; FREDHOLM BB
Journal article: BRAIN RESEARCH. 1994;23(4):354-358
CHANGES IN ADENOSINE RECEPTORS IN THE NEONATAL RAT-BRAIN FOLLOWING HYPOXIC ISCHEMIA
ADEN U; LINDSTROM K; BONA E; HAGBERG H; FREDHOLM BB
Journal article: PHARMACOLOGICAL REVIEWS. 1994;46(2):143-156
Nomenclature and classification of purinoceptors.
Fredholm BB; Abbracchio MP; Burnstock G; Daly JW; Harden TK; Jacobson KA; Leff P; Williams M
Journal article: NEUROSCIENCE. 1994;59(4):837-849
DIFFERENCES IN THE REGIONAL AND CELLULAR-LOCALIZATION OF C-FOS MESSENGER-RNA INDUCED BY AMPHETAMINE, COCAINE AND CAFFEINE IN THE RAT
JOHANSSON B; LINDSTROM K; FREDHOLM BB
Journal article: FEBS LETTERS. 1994;342(1):76-80
Expression of protein kinase C isoforms in smooth muscle cells in various states of differentiation.
Assender JW; Kontny E; Fredholm BB
Journal article: LAKARTIDNINGEN. 1994;91(12):1177-1181
[The mechanism of acetylsalicylic acid becomes clearer].
Fredholm BB
Journal article: JOURNAL OF NEUROCHEMISTRY. 1994;62(2):563-573
PROPENTOFYLLINE AND OTHER ADENOSINE TRANSPORT INHIBITORS INCREASE THE EFFLUX OF ADENOSINE FOLLOWING ELECTRICAL OR METABOLIC STIMULATION OF RAT HIPPOCAMPAL SLICES
FREDHOLM BB; LINDSTROM K; WALLMANJOHANSSON A
Journal article: NORDISK MEDICIN. 1994;109(6-7):202-205
[Clarification of mechanism of acetylsalicylic acid].
Fredholm B
Journal article: LIFE SCIENCES. 1994;55(9):721-728
Release of adenosine and other purines from hippocampal slices stimulated electrically or by hypoxia/hypoglycemia. Effect of chlormethiazole.
Wallman-Johansson A; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1993;149(4):527-529
CAFFEINE-INDUCED EXPRESSION OF THE PROTO-ONCOGENE C-FOS IN RAT STRIATUM IS INCREASED AFTER DOPAMINE DENERVATION
JOHANSSON B; HERRERAMARSCHITZ M; SVENNINGSON P; FREDHOLM BB
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1993;14(12):454-455
Caffeine, coffee, and health Edited by Silvio Garattini, Raven Press, 1992. $124.00 (432 pages) ISBN 0 88167 961 5
Fredholm BB
Journal article: JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 1993;267(2):801-808
EFFECTS OF ADENOSINE-A(1) AND ADENOSINE-A(2) RECEPTOR ACTIVATION ON ELECTRICALLY-EVOKED DOPAMINE AND ACETYLCHOLINE-RELEASE FROM RAT STRIATAL SLICES
JIN SY; JOHANSSON B; FREDHOLM BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1993;247(2):103-110
THE BINDING OF THE ADENOSINE-A2 RECEPTOR-SELECTIVE AGONIST [H-3] CGS-21680 TO RAT CORTEX DIFFERS FROM ITS BINDING TO RAT STRIATUM
JOHANSSON B; GEORGIEV V; PARKINSON FE; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1993;149(1):41-49
Breakdown of membrane choline-phospholipids induced by endogenous and exogenous muscarinic agonist is potentiated by VIP in rat submandibular gland.
Dunér-Engström M; Fredholm BB
Journal article: NEUROCHEMISTRY INTERNATIONAL. 1993;23(2):173-185
INTRACELLULAR FORMATION AND RELEASE OF ADENOSINE FROM RAT HIPPOCAMPAL SLICES EVOKED BY ELECTRICAL-STIMULATION OR ENERGY DEPLETION
LLOYD HGE; LINDSTROM K; FREDHOLM BB
Journal article: BRAIN RESEARCH. 1993;612(1-2):271-277
LONG-TERM CAFFEINE TREATMENT LEADS TO A DECREASED SUSCEPTIBILITY TO NMDA-INDUCED CLONIC SEIZURES IN MICE WITHOUT CHANGES IN ADENOSINE-A(1) RECEPTOR NUMBER
GEORGIEV V; JOHANSSON B; FREDHOLM BB
Journal article: CELLULAR SIGNALLING. 1993;5(3):279-288
Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.
Altiok N; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1993;147(4):461-463
Presynaptic regulation of hippocampal acetylcholine release is unaffected by calcium channel blockers and intracellular calcium chelation.
Fredholm BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1993;347(4):407-414
EFFECT OF LONG-TERM CAFFEINE TREATMENT ON A(1) AND A(2) ADENOSINE RECEPTOR-BINDING AND ON MESSENGER-RNA LEVELS IN RAT-BRAIN
JOHANSSON B; AHLBERG S; VANDERPLOEG I; BRENE S; LINDEFORS N; PERSSON H; FREDHOLM BB
Journal article: JOURNAL OF PHYSIOLOGY-LONDON. 1993;463:349-365
STIMULATION OF THE KATP CHANNEL BY ADP AND DIAZOXIDE REQUIRES NUCLEOTIDE HYDROLYSIS IN MOUSE PANCREATIC BETA-CELLS
LARSSON O; AMMALA C; BOKVIST K; FREDHOLM B; RORSMAN P
Journal article: NEUROCHEMISTRY INTERNATIONAL. 1993;22(3):213-222
INTRAMEMBRANE RECEPTOR RECEPTOR INTERACTIONS - INTEGRATION OF SIGNAL TRANSDUCTION PATHWAYS IN THE NERVOUS-SYSTEM
AGNATI LF; FUXE K; BENFENATI F; VONEULER G; FREDHOLM B
Journal article: DRUG DEVELOPMENT RESEARCH. 1993;28(3):349-353
NEUROMODULATORY ROLES OF PURINES
FREDHOLM BB; JOHANSSON B; VANDERPLOEG I; HU PS; JIN SY
Journal article: DRUG DEVELOPMENT RESEARCH. 1993;28(3):207-213
Purinoceptor nomenclature: A status report
Abbracchio MP; Cattabeni F; Fredholm BB; Williams M
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1993;244(2):111-117
ROLE OF PROTEIN-KINASE-C IN BRADYKININ-INDUCED PROSTAGLANDIN FORMATION IN OSTEOBLASTS
LJUNGGREN O; FREDHOLM BB; NORDSTEDT C; LJUNGHALL S; LERNER UH
Journal article: DRUG DESIGN AND DISCOVERY. 1993;9(3-4):189-197
Signalling via G-protein coupled receptors--using adenosine receptors as an example.
Fredholm BB; Gerwins P; Johansson B; Parkinson FE; van der Ploeg I
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1993;108(1):126-131
Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices.
Fredholm BB; Hu PS
Journal article: JOURNAL OF MOLECULAR NEUROSCIENCE. 1993;4(4):205-214
SYNERGISTIC EFFECTS BETWEEN PROTEIN-KINASE-C AND CAMP ON ACTIVATOR PROTEIN-1 ACTIVITY AND DIFFERENTIATION OF PC-12 PHEOCHROMOCYTOMA CELLS
KVANTA A; FREDHOLM BB
Journal article: BIOCHEMICAL PHARMACOLOGY. 1992;44(12):2365-2370
EFFECTS OF MONOVALENT AND DIVALENT IONS ON THE BINDING OF THE ADENOSINE ANALOG CGS-21680 TO ADENOSINE-A2 RECEPTORS IN RAT STRIATUM
JOHANSSON B; PARKINSON FE; FREDHOLM BB
Journal article: NEUROSCIENCE. 1992;51(3):501-512
ADENOSINE DOPAMINE INTERACTIONS IN THE BRAIN
FERRE S; FUXE K; VONEULER G; JOHANSSON B; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1992;146(4):539-541
EVIDENCE THAT THE INCREASE IN STRIATAL C-FOS FOLLOWING ACUTE HIGH-DOSE CAFFEINE IS NOT DUE TO DIRECT INTERACTION WITH STRIATAL ADENOSINE RECEPTORS
JOHANSSON B; SVENNINGSSON P; ADEN U; LINDSTROM K; FREDHOLM BB
Journal article: BRAIN RESEARCH. 1992;596(1-2):65-72
EFFECT OF THE NEUROTOXIN AF64A ON INTRINSIC AND EXTRINSIC NEURONAL SYSTEMS OF RAT NEOSTRIATUM MEASURED BY INVIVO MICRODIALYSIS
MEANA JJ; JOHANSSON B; HERRERAMARSCHITZ M; OCONNOR WT; GOINY M; PARKINSON FE; FREDHOLM BB; UNGERSTEDT U
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1992;227(3):333-338
ACTIVATION OF PROTEIN-KINASE-C AND ELEVATION OF CAMP INTERACT SYNERGISTICALLY TO RAISE C-FOS AND AP-1 ACTIVITY IN JURKAT CELLS
KONTNY E; KVANTA A; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1992;146(3):357-367
EFFECTS OF ACUTE AND LONG-TERM ATROPINE TREATMENT ON LEVELS, RELEASE AND RESPONSE TO VIP AND PHI IN THE SUBMANDIBULAR-GLAND OF CAT AND RAT
DUNERENGSTROM M; LARSSON O; FREDHOLM BB; LUNDBLAD L; FAHRENKRUG J; LUNDBERG JM
Journal article: LAKARTIDNINGEN. 1992;89(43):3555-364
[Two share the Nobel Prize in medicine this year].
Fredholm BB
Journal article: LAKARTIDNINGEN. 1992;89(43):3568-3572
[Cancer mutations and normal cell regulation].
Fredholm BB
Journal article: JOURNAL OF NEUROSCIENCE RESEARCH. 1992;33(1):37-46
MECHANISMS OF NERVE GROWTH-FACTOR MESSENGER-RNA REGULATION BY INTERLEUKIN-1-BETA IN HIPPOCAMPAL CULTURES - ROLE OF 2ND MESSENGERS
FRIEDMAN WJ; ALTIOK N; FREDHOLM BB; PERSSON H
Journal article: NEUROCHEMISTRY INTERNATIONAL. 1992;21(2):209-213
Bradykinin inhibition of cyclic AMP accumulation in D384 astrocytoma cells. Evidence against a role of cyclic GMP.
Altiok N; Fredholm BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1992;346(3):303-310
Identification of a B2-bradykinin receptor linked to phospholipase C and inhibition of dopamine stimulated cyclic AMP accumulation in the human astrocytoma cell line D384.
Balmforth AJ; Parkinson FE; Altiok N; Fredholm BB
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1992;267(23):16081-16087
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Gerwins P; Fredholm BB
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1992;89(16):7330-7334
Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells.
Gerwins P; Fredholm BB
Journal article: LAKARTIDNINGEN. 1992;89(28-29):2421-2422
[The NSAID gastropathy--a new hypothesis on the etiology].
Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1992;145(1):77-78
GLYCINE AND GABA POTENTIATE 4-AMINOPYRIDINE AND OR N-METHYL-D-ASPARTATE INDUCED [H-3] NORADRENALINE RELEASE FROM RAT HIPPOCAMPAL SLICES
HU PS; JIN S; FREDHOLM BB
Journal article: CELLULAR SIGNALLING. 1992;4(3):275-286
MITOGEN STIMULATION OF T-CELLS INCREASES C-FOS AND C-JUN PROTEIN-LEVELS, AP-1 BINDING AND AP-1 TRANSCRIPTIONAL ACTIVITY
KVANTA A; KONTNY E; JONDAL M; OKRET S; FREDHOLM BB
Journal article: JOURNAL OF NEUROCHEMISTRY. 1992;58(4):1221-1229
Effect of pertussis toxin on radioligand binding to rat brain adenosine A1 receptors.
van der Ploeg I; Parkinson FE; Fredholm BB
Journal article: JOURNAL OF NEUROCHEMISTRY. 1992;58(3):941-950
Magnesium-dependent enhancement of endogenous agonist binding to A1 adenosine receptors: a complicating factor in quantitative autoradiography.
Parkinson FE; Fredholm BB
Journal article: LAKARTIDNINGEN. 1992;89(1-2):20-21
[Studies of prescriptions--a starting-point for scientific work].
Fredholm BB; Krakau I
Journal article: NEUROCHEMISTRY INTERNATIONAL. 1992;21:c3
Regulation of adenosine A1 and A2 receptors in rat brain by caffeine
Johansson B; Ahlberg S; Brené S; Ernfors P; van der Ploeg I; Persson H; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1992;144(1):55-63
Adenosine receptor-induced cAMP changes in D384 astrocytoma cells and the effect of bradykinin thereon.
Altiok N; Balmforth AJ; Fredholm BB
Journal article: FUNDAMENTAL & CLINICAL PHARMACOLOGY. 1992;6(3):99-111
FURTHER EVIDENCE THAT PROPENTOFYLLINE (HWA-285) INFLUENCES BOTH ADENOSINE RECEPTORS AND ADENOSINE TRANSPORT
FREDHOLM BB; FASTBOM J; KVANTA A; GERWINS P; PARKINSON F
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1991;209(1-2):87-93
Comparison of the effects of four dendrotoxin peptides, 4-aminopyridine and tetraethylammonium on the electrically evoked [3H]noradrenaline release from rat hippocampus.
Hu PS; Benishin C; Fredholm BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1991;344(5):611-617
ROLE OF A PERTUSSIS TOXIN SENSITIVE G-PROTEIN IN MEDIATING THE EFFECTS OF PHORBOL ESTERS ON RECEPTOR ACTIVATED CYCLIC-AMP ACCUMULATION IN JURKAT CELLS
VANDERPLOEG I; ALTIOK N; KVANTA A; NORDSTEDT C; FREDHOLM BB
Journal article: LAKARTIDNINGEN. 1991;88(42):3467-3468
[The molecular background of our capacity to identify smells].
Fredholm BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1991;202(3):361-366
Effects of propentofylline on adenosine A1 and A2 receptors and nitrobenzylthioinosine-sensitive nucleoside transporters: quantitative autoradiographic analysis.
Parkinson FE; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1991;143(1):139-140
4-AMINOPYRIDINE-INDUCED NORADRENALIN RELEASE FROM THE RAT HIPPOCAMPUS DEPENDS ON THE ACTIVATION OF GLUTAMATE RECEPTORS OF THE NON-NMDA TYPE
HU PS; JIN S; FREDHOLM BB
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1991;88(16):7238-7241
STIMULATION OF HIGH-AFFINITY ADENOSINE-A2 RECEPTORS DECREASES THE AFFINITY OF DOPAMINE D2 RECEPTORS IN RAT STRIATAL MEMBRANES
FERRE S; VONEULER G; JOHANSSON B; FREDHOLM BB; FUXE K
Journal article: MOLECULAR PHARMACOLOGY. 1991;40(2):149-155
Glucocorticoid receptor activation leads to up-regulation of adenosine A1 receptors and down-regulation of adenosine A2 responses in DDT1 MF-2 smooth muscle cells.
Gerwins P; Fredholm BB
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1991;1093(2-3):178-183
CD3-DEPENDENT INCREASE IN CYCLIC-AMP IN HUMAN T-CELLS FOLLOWING STIMULATION OF THE CD2 RECEPTOR
KVANTA A; JONDAL M; FREDHOLM BB
Journal article: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 1991;10(5):955-964
Pharmacological Implications of A Multiplicity of Adenosine Actions in the CNS
Fredholm BB; Ballarin M; Genvins P; Hu P-S; van der Ploeg I; Parkinson F
Journal article: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 1991;10(5):1173-1174
GTP AND IAP SHIFTS ADENOSINE A1-AGONIST BINDING IN SMOOTH-MUSCLE MEMBRANES TO THE LOW AFFINITY STATE, SIMILAR TO THE ONE FOUND IN INTACT-CELLS
GERWINS P; NORDSTEDT C; FREDHOLM BB
Journal article: FEBS LETTERS. 1991;283(2):321-324
TRANSLOCATION OF THE ALPHA-ISOFORMS AND BETA-ISOFORMS OF PROTEIN-KINASE-C FOLLOWING ACTIVATION OF HUMAN LYMPHOCYTE-T
KVANTA A; JONDAL M; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1991;142(2):267-273
On the role of polyamines in bone resorption induced by parathyroid hormone.
Ljunggren O; Fredholm BB; Lerner UH
Journal article: ACTA PHYSIOLOGICA. 1991;142(1):83-90
LOCALIZATION OF SEVERAL G-PROTEIN SUBUNITS TO THE APICAL AND BASOLATERAL MEMBRANES OF CORTICAL TUBULAR CELLS FROM THE RAT-KIDNEY
VANDERPLOEG I; FREDHOLM BB; CARLQUIST M; BERTORELLO A; APERIA A; CELSI G
Journal article: JOURNAL OF BONE AND MINERAL RESEARCH. 1991;6(5):443-452
BRADYKININ INDUCES FORMATION OF INOSITOL PHOSPHATES AND CAUSES AN INCREASE IN CYTOPLASMIC CA2+ IN THE OSTEOBLASTIC CELL-LINE MC3T3-E1
LJUNGGREN O; JOHANSSON H; LJUNGHALL S; FREDHOLM BB; LERNER UH
Journal article: ACTA PHYSIOLOGICA. 1991;142(1):97-103
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism.
Ballarín M; Fredholm BB; Ambrosio S; Mahy N
Journal article: JOURNAL OF INTERNAL MEDICINE. 1991;229(5):391-406
Diversity in receptor signalling: cellular individuality and the search for selective drugs.
Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1991;141(4):573-574
THE ADENOSINE ANALOG-R-PIA INTERACTS WITH SUBSTANCE-P BINDING IN RAT-BRAIN AND SPINAL-CORD
STILLER CO; FASTBOM J; FREDHOLM BB; BRODIN E
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1991;102(3):764-768
4-Aminopyridine-induced increase in basal and stimulation-evoked [3H]-NA release in slices from rat hippocampus: Ca2+ sensitivity and presynaptic control.
Hu PS; Fredholm BB
Journal article: LAKARTIDNINGEN. 1991;88(6):413-421
[Molecular pharmacology--the road to selective pharmacotherapy?].
Fredholm BB
Journal article: JOURNAL OF NEUROCHEMISTRY. 1991;56(1):178-183
NEUROTENSIN DECREASES THE AFFINITY OF DOPAMINE-D2 AGONIST BINDING BY A G-PROTEIN-INDEPENDENT MECHANISM
VONEULER G; VANDERPLOEG I; FREDHOLM BB; FUXE K
Journal article: NEUROSCIENCE. 1991;44(1):205-214
LIMITED DISTRIBUTION OF PERTUSSIS TOXIN IN RAT-BRAIN AFTER INJECTION INTO THE LATERAL CEREBRAL-VENTRICLES
VANDERPLOEG I; CINTRA A; ALTIOK N; ASKELOF P; FUXE K; FREDHOLM BB
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1991;12:76
Adenosine and adenosine receptors edited by M. Williams, Humana Press, 1990. $89.50 (USA), $94.50 (elsewhere) (528 pages) ISBN 0 89603 163 2
Fredholm B
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1990;189(6):363-372
STIMULATION OF THE T-CELL RECEPTOR-CD3 AND RECEPTOR-CD2 WITH OKT3-ANTIBODIES AND OKT11-ANTIBODIES ACTIVATES A COMMON PERTUSSIS TOXIN-INSENSITIVE G-PROTEIN
KVANTA A; GERWINS P; VANDERPLOEG I; NORDSTEDT C; JONDAL M; FREDHOLM BB
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY. 1990;259(6):C904-C910
VIP AND FORSKOLIN ENHANCE CARBACHOL-INDUCED K+ EFFLUX FROM RAT SALIVARY-GLAND FRAGMENTS BY A CA-2+-SENSITIVE MECHANISM
LARSSON O; DETSCH T; FREDHOLM BB
Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1990;603(1):497-499
Sources of Adenosine Released from Hippocampal Slices following Electrical and Hypoxic/Hypoglycemic Stimulation
FREDHOLM BB; LLOYD HG
Journal article: MOLECULAR PHARMACOLOGY. 1990;38(5):660-666
CHARACTERIZATION OF ADENOSINE-A1-RECEPTORS IN INTACT DDT1 MF-2 SMOOTH-MUSCLE CELLS
GERWINS P; NORDSTEDT C; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1990;140(2):245-255
Adenosine A1-receptor-mediated inhibition of evoked acetylcholine release in the rat hippocampus does not depend on protein kinase C.
Fredholm BB
Journal article: ANALYTICAL BIOCHEMISTRY. 1990;189(2):231-234
A MODIFICATION OF A PROTEIN-BINDING METHOD FOR RAPID QUANTIFICATION OF CAMP IN CELL-CULTURE SUPERNATANTS AND BODY-FLUID
NORDSTEDT C; FREDHOLM BB
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1990;100(4):814-818
Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia.
Andiné P; Rudolphi KA; Fredholm BB; Hagberg H
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1990;183(6):2172
THE INVOLVEMENT OF A PERTUSSIS TOXIN SENSITIVE G-PROTEIN IN THE ACTIVATION OF ADENYLATE-CYCLASE IN JURKAT CELLS
ALTIOK N; VANDERPLOEG I; NORDSTEDT C; FREDHOLM BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1990;183(6):2137-2138
GTP AND IAP SHIFTS ADENOSINE-A1-AGONIST BINDING IN SMOOTH-MUSCLE MEMBRANES TO THE LOW AFFINITY STATE, SIMILAR TO THE ONE FOUND IN INTACT-CELLS
GERWINS P; NORDSTEDT C; FREDHOLM BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1990;342(1):85-89
Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand.
Parkinson FE; Fredholm BB
Journal article: BRAIN RESEARCH. 1990;516(2):248-256
PROTECTIVE EFFECT OF ADENOSINE AND A NOVEL XANTHINE DERIVATIVE PROPENTOFYLLINE ON THE CELL-DAMAGE AFTER BILATERAL CAROTID OCCLUSION IN THE GERBIL HIPPOCAMPUS
DUX E; FASTBOM J; UNGERSTEDT U; RUDOLPHI K; FREDHOLM BB
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1990;11(5):175-178
NEW TARGETS FOR DRUG-ACTION - IS HIGH SELECTIVITY ALWAYS BENEFICIAL
FREDHOLM B; ABBOTT A
Journal article: JOURNAL OF NEUROCHEMISTRY. 1990;54(4):1386-1390
Differential sensitivity to blockade by 4-aminopyridine of presynaptic receptors regulating [3H]acetylcholine release from rat hippocampus.
Fredholm BB
Journal article: BRAIN RESEARCH. 1990;507(2):195-199
EFFECTS OF LONG-TERM THEOPHYLLINE TREATMENT ON ADENOSINE-A1-RECEPTORS IN RAT-BRAIN - AUTORADIOGRAPHIC EVIDENCE FOR INCREASED RECEPTOR NUMBER AND ALTERED COUPLING TO G-PROTEINS
FASTBOM J; FREDHOLM BB
Journal article: NEUROSCIENCE. 1990;34(3):759-769
REGIONAL DIFFERENCES IN THE EFFECT OF GUANINE-NUCLEOTIDES ON AGONIST AND ANTAGONIST BINDING TO ADENOSINE A1-RECEPTORS IN RAT-BRAIN, AS REVEALED BY AUTORADIOGRAPHY
FASTBOM J; FREDHOLM BB
Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1990;604:276-288
ROLE OF G-PROTEINS, CYCLIC-AMP, AND ION CHANNELS IN THE INHIBITION OF TRANSMITTER RELEASE BY ADENOSINE
FREDHOLM BB; DUNERENGSTROM M; FASTBOM J; HU PS; VANDERPLOEG I
Journal article: JOURNAL OF PHARMACOLOGICAL SCIENCES. 1990;52:93
P-21 CGS 21680 acts as an atypical partial agonist at A2 receptors on human T-Ieukemia cells
Fredholm BB; Aitiok N; Ahlberg S; Nordstedt C
Journal article: JOURNAL OF PHARMACOLOGICAL SCIENCES. 1990;52:22
S-17 Interactions between adenosine receptors and other membrane receptors
Fredholm BB; Altiok N; Gerwins P; Larsson O; van der Ploeg I; Kvanta A; Nordstedt C
Journal article: CELLULAR SIGNALLING. 1990;2(5):461-470
STIMULATION OF T-CELLS WITH OKT3 ANTIBODIES INCREASES FORSKOLIN BINDING AND CYCLIC-AMP ACCUMULATION
KVANTA A; GERWINS P; JONDAL M; FREDHOLM BB
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1990;66(1):69-72
ANTINOCICEPTIVE EFFECTS AND SPINAL DISTRIBUTION OF 2 ADENOSINE RECEPTOR AGONISTS AFTER INTRATHECAL ADMINISTRATION
FASTBOM J; POST C; FREDHOLM BB
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1990;31(1):103-108
EVIDENCE THAT PROTEIN KINASE-C ACTIVATION IS ESSENTIAL FOR KILLING BY IL-2-ACTIVATED LYMPHOCYTES
KVANTA A; NORDSTEDT C; FREDHOLM B; GULLBERG M; JONDAL M
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1989;172(6):435-441
PERTUSSIS TOXIN TREATMENT COUNTERACTS INTRAMEMBRANE INTERACTIONS BETWEEN NEUROPEPTIDE-Y RECEPTORS AND ALPHA-2-ADRENOCEPTORS
VONEULER G; FUXE K; VANDERPLOEG I; FREDHOLM BB; AGNATI LF
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1989;340(6):715-717
ACTIVATION OF PROTEIN KINASE-C VIA THE T-CELL RECEPTOR COMPLEX POTENTIATES CYCLIC-AMP RESPONSES IN T-CELLS
KVANTA A; NORDSTEDT C; JONDAL M; FREDHOLM BB
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1989;65(5):347-351
Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus.
Fredholm BB; Dunér-Engström M
Journal article: NEUROSCIENCE LETTERS. 1989;103(3):275-280
ISCHEMIC DAMAGE IN GERBIL HIPPOCAMPUS IS REDUCED FOLLOWING UPREGULATION OF ADENOSINE (A1) RECEPTORS BY CAFFEINE TREATMENT
RUDOLPHI KA; KEIL M; FASTBOM J; FREDHOLM BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1989;172(3):249-262
In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus.
Fredholm BB; Proctor W; Van der Ploeg I; Dunwiddie TV
Journal article: JOURNAL OF APPLIED PHYSIOLOGY. 1989;67(2):541-546
ROLE OF ADENOSINE IN HYPOXIC VENTILATORY DEPRESSION
RUNOLD M; LAGERCRANTZ H; PRABHAKAR NR; FREDHOLM BB
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1989;10(8):316
Adenosine and morphine.
Stone TW; Fredholm BB; Phillis JW
Journal article: NEUROSCIENCE LETTERS. 1989;101(3):337-341
PERTUSSIS TOXIN TREATMENT COUNTERACTS THE CARDIOVASCULAR EFFECTS OF NEUROPEPTIDE-Y AND CLONIDINE IN THE AWAKE UNRESTRAINED RAT
FUXE K; VONEULER G; VANDERPLOEG I; FREDHOLM BB; AGNATI LF
Journal article: FEBS LETTERS. 1989;250(2):536-540
CD3 T-CELL RECEPTOR COUPLING TO A PERTUSSIS AND CHOLERA TOXIN-INSENSITIVE G-PROTEIN
KVANTA A; NORDSTEDT C; VANDERPLOEG I; JONDAL M; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1989;136(3):347-353
Alpha 2-adrenoceptor agonist-mediated inhibition of [3H]noradrenaline release from rat hippocampus is reduced by 4-aminopyridine, but that caused by an adenosine analogue or omega-conotoxin is not.
Hu PS; Fredholm BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1989;172(1):51-60
DUAL EFFECTS OF PROTEIN KINASE-C ON RECEPTOR-STIMULATED CAMP ACCUMULATION IN A HUMAN T-CELL LEUKEMIA LINE
NORDSTEDT C; KVANTA A; VANDERPLOEG I; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1989;135(3):263-269
CARBACHOL STIMULATION OF INOSITOL PHOSPHATE ACCUMULATION IN RAT SUBMANDIBULAR-GLAND FRAGMENTS IS NOT MODIFIED BY VIP
LARSSON O; FREDHOLM BB
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY. 1989;256(2):E250-E255
MICRODIALYSIS OF INTERCELLULAR ADENOSINE CONCENTRATION IN SUBCUTANEOUS TISSUE IN HUMANS
LONNROTH P; JANSSON PA; FREDHOLM BB; SMITH U
Journal article: JOURNAL OF NEURAL TRANSMISSION. 1989;75(2):83-99
RECIPROCAL INTERACTIONS BETWEEN ALPHA-2-ADRENOCEPTOR AGONIST AND NEUROPEPTIDE-Y BINDING-SITES IN THE NUCLEUS TRACTUS SOLITARIUS OF THE RAT - A BIOCHEMICAL AND AUTORADIOGRAPHIC ANALYSIS
HARFSTRAND A; FUXE K; AGNATI L; FREDHOLM B
Journal article: BONE AND MINERAL. 1989;5(2):169-181
Forskolin sensitizes parathyroid hormone-induced cyclic AMP response, but not the bone resorptive effect, in mouse calvarial bones.
Lerner UH; Ransjö M; Sahlberg K; Ljunggren O; Fredholm BB
Journal article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1988;157(3):1046-1050
AGONIST BUT NOT PHORBOL ESTER INDUCED DESENSITIZATION OF HUMAN-LYMPHOCYTE PROSTAGLANDIN RECEPTOR IS DEPENDENT ON TUBULIN POLYMERIZATION
NORDSTEDT C; KVANTA A; FREDHOLM BB
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1988;971(2):207-214
REGULATION OF RECEPTOR-MEDIATED CALCIUM INFLUX ACROSS THE PLASMA-MEMBRANE IN A HUMAN-LEUKEMIC T-CELL LINE - EVIDENCE OF ITS DEPENDENCE ON AN INITIAL CALCIUM MOBILIZATION FROM INTRACELLULAR STORES
NG J; FREDHOLM BB; JONDAL M; ANDERSSON T
Journal article: ACTA PHYSIOLOGICA. 1988;134(1):119-126
Evidence that prejunctional adenosine receptors regulating acetylcholine release from rat hippocampal slices are linked to an N-ethylmaleimide-sensitive G-protein, but not to adenylate cyclase or dihydropyridine-sensitive Ca2+-channels.
Dunér-Engström M; Fredholm BB
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 1988;971(2):207-214
Regulation of receptor-mediated calcium influx across the plasma membrane in a human leukemic T-cell line: evidence of its dependence on an initial calcium mobilization from intracellular stores
Ng J; Fredholm BB; Jondal M; Andersson T
Journal article: CARDIOVASCULAR RESEARCH. 1988;22(9):674-678
ADENOSINE INJECTION INTO THE BRACHIAL-ARTERY PRODUCES ISCHEMIA LIKE PAIN OR DISCOMFORT IN THE FOREARM
SYLVEN C; JONZON B; FREDHOLM BB; KAIJSER L
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1988;9(8):280
Fredholm and Dunwiddie reply
Fredholm BB; Dunwiddie TV
Journal article: LAKARTIDNINGEN. 1988;85(25):2251-2254
[New discoveries on receptor mechanisms--disease-related changes were detected].
Fredholm B; Nordstedt C; van der Ploeg I
Journal article: CELLULAR IMMUNOLOGY. 1988;114(1):96-103
PHOSPHOINOSITIDE BREAKDOWN AND EVIDENCE FOR PROTEIN KINASE-C INVOLVEMENT DURING HUMAN NK KILLING
CHOW SC; NG J; NORDSTEDT C; FREDHOLM BB; JONDAL M
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1988;337(5):477-483
PROTEIN KINASE-C ACTIVATION INCREASES NORADRENALINE RELEASE FROM THE RAT HIPPOCAMPUS AND MODIFIES THE INHIBITORY EFFECT OF ALPHA-2-ADRENOCEPTOR AND ADENOSINE A1-RECEPTOR AGONISTS
FREDHOLM BB; LINDGREN E
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1988;9(4):130-134
How does adenosine inhibit transmitter release?
Fredholm BB; Dunwiddie TV
Journal article: BIOCHEMICAL PHARMACOLOGY. 1987;36(22):3943-3949
Studies on the calcium dependence of human NK cell killing.
Ng J; Fredholm BB; Jondal M
Journal article: ACTA PHYSIOLOGICA. 1987;131(3):467-469
REGIONAL DIFFERENCES IN THE GTP-DEPENDENCE OF ADENOSINE RECEPTOR-BINDING IN RAT-BRAIN
FASTBOM J; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1987;131(2):287-296
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Lerner UH; Sahlberg K; Fredholm BB
Journal article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1987;10:s1-s13
Central Catecholamine-Neuropeptide Y Interactions at the Pre- and Postsynaptic Level in Cardiovascular Centers
Fuxe K; Härfstrand A; Agnati LF; Kalia M; Fredholm B; Svensson T; Gustafsson J; Lang R; Ganten D
Journal article: LIFE SCIENCES. 1987;41(7):837-840
Analysis of purines.
Fredholm BB
Journal article: FEBS LETTERS. 1987;220(1):57-60
ACTIVATION OF PROTEIN-KINASE-C INHIBITS PROSTAGLANDIN-STIMULATED AND POTENTIATES ADENOSINE RECEPTOR-STIMULATED ACCUMULATION OF CYCLIC-AMP IN A HUMAN T-CELL LEUKEMIA LINE
NORDSTEDT C; JONDAL M; FREDHOLM BB
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1987;61(2):121-125
INTERACTION OF DIHYDROPYRIDINE CALCIUM-CHANNEL AGONISTS AND ANTAGONISTS WITH ADENOSINE RECEPTORS
HU PS; LINDGREN E; JACOBSON KA; FREDHOLM BB
Journal article: BRAIN RESEARCH. 1987;415(2):323-330
Central versus peripheral mediation of responses to adenosine receptor agonists: evidence against a central mode of action.
Brodie MS; Lee K; Fredholm BB; Ståhle L; Dunwiddie TV
Journal article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1987;145(1):344-349
THE ADENOSINE RECEPTOR MEDIATED ACCUMULATION OF CYCLIC-AMP IN JURKAT CELLS IS ENHANCED BY A LECTIN AND BY PHORBOL ESTERS
FREDHOLM BB; JONDAL M; NORDSTEDT C
Journal article: NEUROSCIENCE LETTERS. 1987;76(2):185-190
INHIBITORY EFFECTS OF NEUROPEPTIDE-Y ON CYCLIC-AMP ACCUMULATION IN SLICES OF THE NUCLEUS TRACTUS SOLITARIUS REGION OF THE RAT
HARFSTRAND A; FREDHOLM B; FUXE K
Journal article: ACTA PHYSIOLOGICA. 1987;130(1):95-105
EFFECTS OF N-ETHYLMALEIMIDE AND FORSKOLIN ON NORADRENALINE RELEASE FROM RAT HIPPOCAMPAL SLICES - EVIDENCE THAT PREJUNCTIONAL ADENOSINE AND ALPHA-RECEPTORS ARE LINKED TO N-PROTEINS BUT NOT TO ADENYLATE-CYCLASE
FREDHOLM BB; LINDGREN E
Journal article: EXPERIMENTAL CELL RESEARCH. 1987;170(1):153-159
MODULATION OF ARTERIAL SMOOTH-MUSCLE CELLS FROM CONTRACTILE TO SYNTHETIC PHENOTYPE REQUIRES INDUCTION OF ORNITHINE DECARBOXYLASE ACTIVITY AND POLYAMINE SYNTHESIS
THYBERG J; FREDHOLM BB
Journal article: EXPERIMENTAL CELL RESEARCH. 1987;170(1):160-169
INDUCTION OF ORNITHINE DECARBOXYLASE ACTIVITY AND PUTRESCINE SYNTHESIS IN ARTERIAL SMOOTH-MUSCLE CELLS STIMULATED WITH PLATELET-DERIVED GROWTH-FACTOR
THYBERG J; FREDHOLM BB
Journal article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1987;23(3):323-330
ADDITIVE RENAL EFFECTS OF INDOMETHACIN AND DIPYRIDAMOLE IN MAN
SEIDEMAN P; SOLLEVI A; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1987;129(2):189-194
THE DISAPPEARANCE OF ADENOSINE FROM BLOOD AND PLATELET SUSPENSION IN RELATION TO THE PLATELET CYCLIC-AMP CONTENT
SODERBACK U; SOLLEVI A; FREDHOLM BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1987;335(2):136-142
PHORBOL-12,13-DIBUTYRATE ENHANCES THE CYCLIC-AMP ACCUMULATION IN RAT HIPPOCAMPAL SLICES INDUCED BY ADENOSINE-ANALOGS
NORDSTEDT C; FREDHOLM BB
Journal article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1987;10 Suppl 12:S1-13
Central catecholamine-neuropeptide Y interactions at the pre- and postsynaptic level in cardiovascular centers.
Fuxe K; Härfstrand A; Agnati LF; Kalia M; Fredholm B; Svensson T; Gustafsson JA; Lang R; Ganten D
Journal article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 1987;10(Supplement 12):s14
Central Catecholamine-Neuropeptide Y Interactions at the Pre- and Postsynaptic Level in Cardiovascular Centers
Fuxe K; H??rfstrand A; Agnati LF; Kalia M; Fredholm B; Svensson T; Gustafsson J-K; Lang R; Ganten D
Journal article: INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY. 1987;9(1):17-22
CHARACTERIZATION OF PHA AND ANTI-T3 INDUCED TRANSDUCTION MECHANISMS IN A HUMAN T-CELL LEUKEMIA LINE
NG J; FREDHOLM B; JONDAL M; ANDERSSON T
Journal article: JOURNAL OF APPLIED PHYSIOLOGY. 1987;62(4):1759-1760
RESPIRATORY EFFECTS OF AN ADENOSINE ANALOG - REPLY
RUNOLD M; LAGERCRANTZ H; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1986;128(4):659-660
THE DIHYDROPYRIDINE CALCIUM-CHANNEL AGONIST BAYK 8644 INHIBITS THE PRESYNAPTIC EFFECTS OF R-PHENYLISOPROPYL ADENOSINE IN THE RAT HIPPOCAMPUS
FREDHOLM BB; HU PS; LINDGREN E
Journal article: SCANDINAVIAN JOURNAL OF DENTAL RESEARCH. 1986;94(6):507-514
HIGH-DOSES OF FLUORIDE DO NOT AFFECT CYCLIC-AMP LEVELS IN HUMAN AND RAT PLASMA OR URINE
EKSTRAND J; WALLER R; FORSBERG A; FREDHOLM B
Journal article: BIOCHEMICAL PHARMACOLOGY. 1986;35(23):4177-4189
Comparative study of the effects of cyclic nucleotide phosphodiesterase inhibitors on bone resorption and cyclic AMP formation in vitro.
Lerner U; Ransjö M; Fredholm BB
Journal article: BRAIN RESEARCH. 1986;398(1):106-112
RELEASE OF ENDOGENOUS AND RADIOACTIVE PURINES FROM THE RABBIT RETINA
PEREZ MTR; EHINGER BE; LINDSTROM K; FREDHOLM BB
Journal article: JOURNAL OF APPLIED PHYSIOLOGY. 1986;61(1):255-259
VENTILATORY EFFECT OF AN ADENOSINE ANALOG IN UNANESTHETIZED RABBITS DURING DEVELOPMENT
RUNOLD M; LAGERCRANTZ H; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1986;127(3):381-386
EFFECTS OF N-ETHYLMALEIMIDE AND FORSKOLIN ON GLUTAMATE RELEASE FROM RAT HIPPOCAMPAL SLICES - EVIDENCE THAT PREJUNCTIONAL ADENOSINE RECEPTORS ARE LINKED TO N-PROTEINS, BUT NOT TO ADENYLATE-CYCLASE
FREDHOLM BB; FASTBOM J; LINDGREN E
Journal article: ACTA PHYSIOLOGICA. 1986;126(4):551-555
CONTINUOUS MONITORING OF POTASSIUM EFFLUX FROM RAT PAROTID-GLAND FRAGMENTS BY POTASSIUM SELECTIVE ELECTRODES
DUNERENGSTROM M; LARSSON O; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1986;126(4):491-498
EFFECTS OF ADENOSINE AND 2 STABLE ADENOSINE-ANALOGS ON BLOOD-PRESSURE, HEART-RATE AND COLONIC TEMPERATURE IN THE RAT
JONZON B; BERGQUIST A; LI YO; FREDHOLM BB
Journal article: JOURNAL OF PHYSIOLOGY-LONDON. 1986;373:87-96
AUTONOMIC MECHANISMS UNDERLYING CAPSAICIN INDUCED ORAL SENSATIONS AND SALIVATION IN MAN
DUNERENGSTROM M; FREDHOLM BB; LARSSON O; LUNDBERG JM; SARIA A
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1986;58(3):187-192
THE XANTHINE DERIVATIVE 1-(5'-OXOHEXYL)-3-METHYL-7-PROPYL XANTHINE (HWA-285) ENHANCES THE ACTIONS OF ADENOSINE
FREDHOLM BB; LINDSTROM K
Journal article: ACTA PHYSIOLOGICA. 1986;126(2):307-309
POSSIBLE INVOLVEMENT OF THE NI-PROTEIN IN THE PREJUNCTIONAL INHIBITORY EFFECT OF A STABLE ADENOSINE ANALOG (R-PIA) ON NORADRENALINE RELEASE IN THE RAT HIPPOCAMPUS
FREDHOLM BB; LINDGREN E
Journal article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 1986;6(1):1-21
CARDIOVASCULAR EFFECTS OF ADENOSINE
FREDHOLM BB; SOLLEVI A
Journal article: REGULATORY PEPTIDES. 1986;13(3-4):319-326
EFFECTS OF VIP, PHM AND SUBSTANCE-P ON BLOOD-VESSELS AND SECRETORY ELEMENTS OF THE HUMAN SUBMANDIBULAR-GLAND
LARSSON O; DUNERENGSTROM M; LUNDBERG JM; FREDHOLM BB; ANGGARD A
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1986;332(2):173-178
EFFECT OF ADENOSINE RECEPTOR AGONISTS AND OTHER COMPOUNDS ON CYCLIC-AMP ACCUMULATION IN FORSKOLIN-TREATED HIPPOCAMPAL SLICES
FREDHOLM BB; JONZON B; LINDSTROM K
Journal article: SWEDISH DENTAL JOURNAL. SUPPLEMENT. 1986;10(3):93-96
EFFECT OF NICOTINE CHEWING GUM ON SALIVARY SECRETION
DUNERENGSTROM M; LARSSON O; LUNDBERG J; FREDHOLM BB
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1985;86(2):509-513
TREATMENT WITH N-ETHYLMALEIMIDE SELECTIVELY REDUCES ADENOSINE RECEPTOR-MEDIATED DECREASES IN CYCLIC-AMP ACCUMULATION IN RAT HIPPOCAMPAL SLICES
FREDHOLM BB; LINDGREN E; LINDSTROM K
Journal article: ACTA PHYSIOLOGICA. 1985;125(2):341-342
A novel 8-phenyl-substituted xanthine derivative is a selective antagonist at adenosine A1-receptors in vivo.
Jakobson KA; Kirk KL; Daly JW; Jonzon B; Li YO; Fredholm BB
Journal article: JOURNAL OF CELLULAR PHYSIOLOGY. 1985;124(3):451-456
ADENOSINE RECEPTOR-MEDIATED CHANGES IN CYCLIC-AMP PRODUCTION AND DNA-SYNTHESIS IN CULTURED ARTERIAL SMOOTH-MUSCLE CELLS
JONZON B; NILSSON J; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1985;125(1):121-123
INHIBITION OF [H-3] GLUTAMATE RELEASE FROM RAT HIPPOCAMPAL SLICES BY L-PHENYLISOPROPYLADENOSINE
FASTBOM J; FREDHOLM BB
Journal article: JOURNAL OF ORAL PATHOLOGY. 1985;14(8):644-653
Diphenylhydantoin inhibits parathyroid hormone and prostaglandin E2-stimulated bone resorption in mouse calvaria without affecting cyclic AMP formation.
Lerner U; Fredholm BB; Hänström L
Journal article: ACTA PHYSIOLOGICA. 1985;124(4):581-589
Studies on the oxygen radical mechanism involved in the small intestinal reperfusion damage.
Schoenberg MH; Fredholm BB; Haglund U; Jung H; Sellin D; Younes M; Schildberg FW
Journal article: NEUROSCIENCE LETTERS. 1985;58(2):213-217
Perivascular peptides relax cerebral arteries concomitant with stimulation of cyclic adenosine monophosphate accumulation or release of an endothelium-derived relaxing factor in the cat.
Edvinsson L; Fredholm BB; Hamel E; Jansen I; Verrecchia C
Journal article: LIFE SCIENCES. 1985;37(3):289-297
Inhibition of Purkinje cell firing by systemic administration of phenylisopropyl adenosine: effect of central noradrenaline depletion by DSP4.
Bickford PC; Fredholm BB; Dunwiddie TV; Freedman R
Journal article: ACTA PHYSIOLOGICA. 1985;124(3):467-469
Neuropeptide Y is a potent inhibitor of cyclic AMP accumulation in feline cerebral blood vessels.
Fredholm BB; Jansen I; Edvinsson L
Journal article: ACTA PHYSIOLOGICA. 1985;124(2):253-259
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Li YO; Fredholm BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1985;111(1):133-136
Behavioural sensitivity to PIA in selectively bred mice is related to a number of A1 adenosine receptors but not to cyclic AMP accumulation in brain slices.
Fredholm BB; Zahniser NR; Weiner GR; Proctor WR; Dunwiddie TV
Journal article: BIOCHEMICAL PHARMACOLOGY. 1985;34(7):937-940
Prostaglandin E2 and 2-chloroadenosine act in concert to stimulate bone resorption in cultured murine calvarial bones.
Lerner U; Fredholm BB
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1985;84(3):625-630
The adenosine receptor activity of EMD 28422, a purine derivative with reported actions on benzodiazepine receptors.
Dunwiddie TV; Fredholm BB; Jonzon B; Sandberg G
Journal article: ACTA PHYSIOLOGICA. 1985;123(2):183-189
ACTIONS OF ENPROFYLLINE IN THE RAT HIPPOCAMPUS
FREDHOLM BB; BERGMAN B; LINDSTROM K
Journal article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1985;15(1):15-19
Differences in basal and stimulated cyclic AMP content in calvaria bones from normal mice and mice with an impaired lysosomal function (beige mice).
Ransjö M; Fredholm BB; Lerner U; Gustafson GT
Journal article: ACTA MEDICA SCANDINAVICA. 1985;217(2):149-153
On the mechanism of action of theophylline and caffeine.
Fredholm BB
Journal article: SCANDINAVIAN JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 1985;19(2):155-159
ADENOSINE SPARES PLATELETS DURING CARDIOPULMONARY BYPASS IN MAN WITHOUT CAUSING SYSTEMIC VASODILATATION
SOLLEVI A; TORSSELL L; FREDHOLM BB; SETTERGREN G; BLOMBACK M
Journal article: JOURNAL OF NEUROCHEMISTRY. 1985;44(1):217-224
Release of purines, noradrenaline, and GABA from rat hippocampal slices by field stimulation.
Jonzon B; Fredholm BB
Journal article: JOURNAL OF PHARMACY AND PHARMACOLOGY. 1984;36(12):846-848
Adenosine mechanisms are not affected by antidepressant concentrations of desipramine.
Jonzon B; Fredholm BB
Journal article: LIFE SCIENCES. 1984;35(19):1971-1979
Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus.
Jonzon B; Fredholm BB
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1984;55(4):297-302
ADENOSINE-ANALOGS STIMULATE CYCLIC AMP-ACCUMULATION IN CULTURED NEURO-BLASTOMA AND GLIOMA-CELLS
ELFMAN L; LINDGREN E; WALUM E; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1984;122(1):55-59
CHANGES IN NORADRENALINE RELEASE AND IN BETA-RECEPTOR NUMBER IN RAT HIPPOCAMPUS FOLLOWING LONG-TERM TREATMENT WITH THEOPHYLLINE OR L-PHENYLISOPROPYLADENOSINE
FREDHOLM BB; JONZON B; LINDGREN E
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1984;326(4):294-301
Adenosine receptors mediating inhibitory electrophysiological responses in rat hippocampus are different from receptors mediating cyclic AMP accumulation.
Dunwiddie TV; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1984;121(2):155-163
Accumulation and inactivation of adenosine by fat cells from hypothyroid rats.
Fredholm BB; Vernet L
Journal article: PEDIATRIC RESEARCH. 1984;18(4):387-390
ADENOSINE-ANALOGS DEPRESS VENTILATION IN RABBIT NEONATES - THEOPHYLLINE STIMULATION OF RESPIRATION VIA ADENOSINE RECEPTORS
LAGERCRANTZ H; YAMAMOTO Y; FREDHOLM BB; PRABHAKAR NR; VONEULER C
Journal article: ACTA PHYSIOLOGICA. 1984;120(4):551-555
Adenine nucleotide levels and adenosine metabolism in cultured calvarial bone.
Fredholm BB; Lerner U
Journal article: ACTA PHYSIOLOGICA. 1984;120(4):523-528
Calcium-dependent enhancement by carbachol of the VIP-induced cyclic AMP accumulation in cat submandibular gland.
Enyedi P; Fredholm BB
Journal article: BRAIN RESEARCH. 1984;295(1):127-136
LEVELS OF ADENOSINE AND ADENINE-NUCLEOTIDES IN SLICES OF RAT HIPPOCAMPUS
FREDHOLM BB; DUNWIDDIE TV; BERGMAN B; LINDSTROM K
Journal article: ACTA PHYSIOLOGICA. 1984;120(3):333-336
Adenosine and adenosine analogues increase blood flow in oral mucosa.
Gazelius B; Sidhagen B; Fredholm BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1984;325(2):176-182
Capsaicin-induced stimulation of the guinea-pig atrium. Involvement of a novel sensory transmitter or a direct action on myocytes?
Lundberg JM; Hua Y; Fredholm BB
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1984;54(1):64-71
THE EFFECT OF ALKYLXANTHINES AND OTHER PHOSPHODIESTERASE INHIBITORS ON ADENOSINE-RECEPTOR MEDIATED DECREASE IN LIPOLYSIS AND CYCLIC-AMP ACCUMULATION IN RAT FAT-CELLS
FREDHOLM BB; LINDGREN E
Journal article: CLINICAL AND EXPERIMENTAL MEDICINE. 1984;184(4):259-264
Oxidative tissue damage following regional intestinal ischemia and reperfusion in the cat.
Younes M; Schoenberg MH; Jung H; Fredholm BB; Haglund U; Schildberg FW
Journal article: ACTA PHYSIOLOGICA. 1984;120(1):159-160
Transient inhibition on calcium mobilization from cultured mouse calvarial bones by the adenylate cyclase stimulator forskolin.
Lerner U; Fredholm BB; Ransjö M
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1983;80(4):631-637
Characterization of adenosine receptors in isolated cerebral arteries of cat.
Edvinsson L; Fredholm BB
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1983;80(4):639-644
Inhibition by xanthine derivatives of adenosine receptor-stimulated cyclic adenosine 3',5'-monophosphate accumulation in rat and guinea-pig thymocytes.
Fredholm BB; Sandberg G
Journal article: CHIRURG. 1983;54(11):728-733
CHANGES IN THE ACID-BASE STATUS, THE SERUM LACTATE CONCENTRATION AND IN PURINE METABOLISM IN ARTERIAL RECONSTRUCTION
SCHOENBERG M; FREDHOLM B; HOHLBACH G; SCHILDBERG FW
Journal article: PLASTIC AND RECONSTRUCTIVE SURGERY. 1983;72(4):518-523
ON THE MECHANISM BY WHICH ANTIADRENERGIC DRUGS INCREASE SURVIVAL OF CRITICAL SKIN FLAPS
JURELL G; HJEMDAHL P; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1983;:7-10
INHIBITION OF NORADRENALINE RELEASE FROM HIPPOCAMPAL SLICES BY A STABLE ADENOSINE ANALOG
FREDHOLM BB; JONZON B; LINDGREN E
Journal article: MEDICAL BIOLOGY. 1983;61(6):324-330
PGE1 AND PROSTACYCLIN SUPPRESSION OF NK-CELL MEDIATED CYTO-TOXICITY AND ITS RELATION TO CYCLIC-AMP
LANEFELT F; ULLBERG M; JONDAL M; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1982;116(3):285-295
RELEASE OF NUCLEOSIDES AND NUCLEOTIDES FROM THE RABBIT HEART BY SYMPATHETIC-NERVE STIMULATION
FREDHOLM BB; HEDQVIST P; LINDSTROM K; WENNMALM M
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1982;51(4):336-344
COMPARISON OF THE EFFECTS OF DIFFERENT ARACHIDONIC-ACID METABOLITES ON CYCLIC-NUCLEOTIDE ACCUMULATION IN HUMAN PERIPHERAL LYMPHOCYTES
LANEFELT F; MARTINSSON A; HJEMDAHL P; FREDHOLM BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1982;81(4):673-676
Xanthine derivatives as adenosine receptor antagonists.
Fredholm BB; Persson CG
Journal article: JOURNAL OF NEUROCHEMISTRY. 1982;39(1):165-175
ADENOSINE RECEPTORS MEDIATING CYCLIC-AMP PRODUCTION IN THE RAT HIPPOCAMPUS
FREDHOLM BB; JONZON B; LINDGREN E; LINDSTROM K
Journal article: DIABETES CARE. 1982;5(4):409-413
PROFILES OF INTERMEDIARY METABOLITES IN INSULIN-DEPENDENT PREGNANT DIABETIC WOMEN WITH OR WITHOUT ENDOGENOUS INSULIN PRODUCTION
STANGENBERG M; PERSSON B; FREDHOLM BB; LUNELL NO
Journal article: JOURNAL OF DENTAL RESEARCH. 1982;61(6):761-763
FORMATION OF 12L-HYDROXYEICOSATETRAENOIC ACID (12-HETE) BY GINGIVAL TISSUE
SIDHAGEN B; HAMBERG M; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1982;115(2):283-286
Adenosine actions and adenosine receptors after 1 week treatment with caffeine.
Fredholm BB
Journal article: ACTA ENDOCRINOLOGICA. 1982;100(2):313-320
2-chloroadenosine increases calcium mobilization from mouse calvaria in vitro.
Lerner U; Fredholm BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1982;79(3-4):233-243
Origin of adenosine released from rat vas deferens by nerve stimulation.
Fredholm BB; Fried G; Hedqvist P
Journal article: NEUROSCIENCE LETTERS. 1982;29(2):111-115
PURINE LEVELS IN THE INTACT RAT-BRAIN - STUDIES WITH AN IMPLANTED PERFUSED HOLLOW FIBER
ZETTERSTROM T; VERNET L; UNGERSTEDT U; TOSSMAN U; JONZON B; FREDHOLM BB
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1982;79(1-2):139-143
Carbachol potentiates the cyclic AMP-stimulating effect of VIP in cat submandibular gland.
Enyedi P; Fredholm BB; Lundberg JM; Anggård A
Journal article: ACTA PHYSIOLOGICA. 1982;114(2):243-251
On the mechanism by which theophylline inhibits histamine release from rat mast cells.
Sydbom A; Fredholm BB
Journal article: ACTA MEDICA SCANDINAVICA, SUPPLEMENT. 1982;665:143-147
LABETALOL, A COMBINED ALPHA-BLOCKER AND BETA-BLOCKER, IN HYPERTENSION OF PREGNANCY
LUNELL NO; FREDHOLM B; HJEMDAHL P; LEWANDER R; NISELL H; NYLUND L; PERSSON B; SARBY B; WAGER J; THORNSTROM S
Journal article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, SUPPLEMENT. 1982;108:53-59
DEVELOPMENT OF TOLERANCE TO THE METABOLIC ACTIONS OF BETA-2-ADRENOCEPTOR STIMULATING DRUGS
FREDHOLM BB; LUNELL NO; PERSSON B; WAGER J
Journal article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, SUPPLEMENT. 1982;108:41-46
METABOLIC AND CIRCULATORY EFFECTS OF INTRAVENOUS AND ORAL SALBUTAMOL IN LATE PREGNANCY IN DIABETIC AND NON-DIABETIC WOMEN
WAGER J; FREDHOLM B; LUNELL NO; PERSSON B
Journal article: GYNECOLOGIC AND OBSTETRIC INVESTIGATION. 1982;13(3):184-188
DECREASED ADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE CONCENTRATION IN AMNIOTIC-FLUID DURING RIVANOL-INDUCED ABORTION
BISTOLETTI P; OLUND A; LUNELL NO; FREDHOLM B
Journal article: ACTA PHYSIOLOGICA. 1982;114(1):111-119
METABOLIC AND HORMONAL ADJUSTMENTS DURING HEMORRHAGE IN CATS AFTER INTERFERENCE WITH THE SYMPATHO-ADRENAL SYSTEM
ANDERSSON PO; FARNEBO LO; FREDHOLM BB; HAMBERGER B; HOLST J; JARHULT J
Journal article: ACTA PHYSIOLOGICA. 1982;114(1):157-159
VIP-induced cyclic AMP formation in the cat submandibular gland. Potentiation by carbacholine.
Fredholm BB; Lundberg JM
Journal article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1981;12(4):489-495
DEVELOPMENT OF TOLERANCE TO ORAL SALBUTAMOL IN THE 3RD TRIMESTER OF PREGNANCY - A STUDY OF CIRCULATORY AND METABOLIC EFFECTS
WAGER J; FREDHOLM BB; LUNELL NO; PERSSON B
Journal article: ACTA PHYSIOLOGICA. 1981;113(1):53-60
THE ANTILIPOLYTIC EFFECT OF ENDOGENOUS AND EXOGENOUS ADENOSINE IN CANINE ADIPOSE-TISSUE INSITU
SOLLEVI A; FREDHOLM BB
Journal article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1981;12(3):345-348
CIRCULATORY AND METABOLIC EFFECTS OF A COMBINED ALPHA-ADRENOCEPTOR AND BETA-ADRENOCEPTOR BLOCKER (LABETALOL) IN HYPERTENSION OF PREGNANCY
LUNELL NO; HJEMDAHL P; FREDHOLM BB; NISELL H; PERSSON B; WAGER J
Journal article: ACTA PHYSIOLOGICA. 1981;113(1):33-36
Early changes in ATP and cyclic AMP levels in experimental critical skin flaps.
Jurell G; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1981;112(3):293-298
ROLE OF ADENOSINE IN ADIPOSE-TISSUE CIRCULATION
SOLLEVI A; FREDHOLM BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1981;316(4):326-330
Alkylxanthines elevate hippocampal excitability. Evidence for a role of endogenous adenosine.
Dunwiddie TV; Hoffer BJ; Fredholm BB
Journal article: BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 1981;88(6):619-627
INSULIN-INDUCED HYPOGLYCEMIA IN DIABETIC WOMEN DURING LATE PREGNANCY AND ONE YEAR POST PARTUM
STANGENBERG M; PERSSON B; FREDHOLM BB; LINDBLAD BS; STANGE L
Journal article: ACTA PHYSIOLOGICA. 1981;112(1):47-56
EVIDENCE AGAINST A ROLE OF CYCLIC-NUCLEOTIDES IN THE REGULATION OF ANAPHYLACTIC HISTAMINE-RELEASE IN ISOLATED RAT MAST-CELLS
SYDBOM A; FREDHOLM B; UVNAS B
Journal article: BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 1981;88(4):352-361
METABOLIC AND CIRCULATORY EFFECTS OF ORAL SALBUTAMOL IN THE 3RD TRIMESTER OF PREGNANCY IN DIABETIC AND NON-DIABETIC WOMEN
WAGER J; FREDHOLM BB; LUNELL NO; PERSSON B
Journal article: ACTA PHYSIOLOGICA. 1981;111(4):507-508
Release of adenosine from rat lung by antigen and compound 48/80.
Fredholm BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1981;316(2):112-119
ENDOGENOUS ADENOSINE INHIBITS LIPOLYSIS INDUCED BY NERVE-STIMULATION WITHOUT INHIBITING NORADRENALINE RELEASE IN CANINE SUBCUTANEOUS ADIPOSE-TISSUE INVIVO
SOLLEVI A; HJEMDAHL P; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1981;111(3):249-257
ANAPHYLACTIC SHOCK IN MONKEYS PASSIVELY SENSITIZED WITH HUMAN REAGINIC SERUM .2. RESPIRATORY MECHANICS, HEMATOLOGY AND METABOLISM
REVENAS B; SMEDEGARD G; SALDEEN T; FREDHOLM BB; STRANDBERG K
Journal article: ACTA PHYSIOLOGICA. 1981;111(3):269-280
THEOPHYLLINE INTERFERES WITH THE MODULATORY ROLE OF ENDOGENOUS ADENOSINE ON CHOLINERGIC NEUROTRANSMISSION IN GUINEA-PIG ILEUM
GUSTAFSSON L; FREDHOLM BB; HEDQVIST P
Journal article: NEONATOLOGY. 1981;40(3-4):145-149
CYCLIC 3',5'-ADENOSINE-MONOPHOSPHATE IN UMBILICAL-CORD BLOOD OF THE NEWBORN-INFANT - RELATION TO FETAL STRESS AND PLASMA-CATECHOLAMINES
BISTOLETTI P; FREDHOLM BB; LAGERCRANTZ H
Journal article: JOURNAL OF PHYSIOLOGY-LONDON. 1981;313(APR):351-367
THE RELEASE OF ADENOSINE AND INOSINE FROM CANINE SUBCUTANEOUS ADIPOSE-TISSUE BY NERVE-STIMULATION AND NORADRENALINE
FREDHOLM BB; SOLLEVI A
Journal article: PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 1980;210(1178):63-77
CELLULAR-LOCALIZATION OF PEPTIDES IN NEURAL STRUCTURES
HOKFELT T; LUNDBERG JM; SCHULTZBERG M; PEARSE AGE; JOHANSSON O; SKIRBOLL L; ANGGARD A; FREDHOLM B; HAMBERGER B; PERNOW B; REHFELD J; GOLDSTEIN M; GARRETT JR
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1980;47(1):58-65
Effects of ethanol on human lymphocyte levels of cyclic AMP. In vitro: Potentiation of the response to isoproterenol, prostaglandin E2 or adenosine stimulation.
Hynie S; Lanefelt F; Fredholm BB
Journal article: BIOCHEMICAL PHARMACOLOGY. 1980;29(12):1635-1643
Modulation of neurotransmission by purine nucleotides and nucleosides.
Fredholm BB; Hedqvist P
Journal article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 1980;24(3):206-210
CYCLIC-AMP AND METABOLIC SUBSTRATES FOLLOWING HEMORRHAGE IN AWAKE AND ANESTHETIZED RATS
FARNEBO LO; FREDHOLM BB; HAMBERGER B
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1979;45(5):336-344
MECHANISM OF RELAXATION OF TRACHEAL MUSCLE BY THEOPHYLLINE AND OTHER CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS
FREDHOLM BB; BRODIN K; STRANDBERG K
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1979;58(4):389-397
Release of radioactive purines from cat nictitating membrane labeled with 3H-adenine.
Luchelli-Fortis MA; Fredholm BB; Langer SZ
Journal article: ACTA PHYSIOLOGICA. 1979;106(4):473-479
Effect of sensitization on spontaneous and phosphatidylserine-induced histamine release and on cyclic AMP and GMP levels in isolated rat mast cells.
Sydbom A; Fredholm BB; Uvnäs B
Journal article: ACTA PHYSIOLOGICA. 1979;106(3):381-382
Release of adenosine from the rabbit heart by sympathetic nerve stimulation.
Fredholm BB; Hedqvist P; Vernet L
Journal article: ACTA PHYSIOLOGICA. 1979;106(2):97-107
Release of 3H-nucleosides from 3H-adenine labelled hypothalamic synaptosomes.
Fredholm BB; Vernet L
Journal article: ACTA PHYSIOLOGICA. 1979;105(4):481-495
PLASMA-CATECHOLAMINES, CYCLIC-AMP AND METABOLIC SUBSTRATES IN HEMORRHAGIC-SHOCK OF THE RAT - EFFECT OF ADRENAL DEMEDULLATION AND 6-OH-DOPAMINE TREATMENT
FREDHOLM BB; FARNEBO LO; HAMBERGER B
Journal article: ACTA PHYSIOLOGICA. 1979;105(3):257-267
UPTAKE AND RELEASE OF ADENOSINE IN ISOLATED RAT FAT-CELLS
FREDHOLM BB; HJEMDAHL P
Journal article: ACTA PHYSIOLOGICA. 1979;105(2):222-227
METABOLIC EFFECTS OF BLOOD-FLOW RESTRICTION IN ADIPOSE-TISSUE
BELFRAGE E; HJEMDAHL P; FREDHOLM BB
Journal article: GYNECOLOGIC AND OBSTETRIC INVESTIGATION. 1979;10(1):39-45
ACUTE METABOLIC AND CIRCULATORY EFFECTS OF CIGARETTE-SMOKING IN LATE PREGNANCY
NYLUND L; LUNELL NO; PERSSON B; FREDHOLM BB; LAGERCRANTZ H
Journal article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 1979;58(5):443-445
CIRCULATORY AND METABOLIC EFFECTS OF ACUTE BETA1-BLOCKADE IN SEVERE PRE-ECLAMPSIA
LUNELL NO; PERSSON B; ARAGON G; FREDHOLM BB; ASTROM H
Journal article: TRENDS IN PHARMACOLOGICAL SCIENCES. 1979;1(1):129-132
Are methylxanthine effects due to antagonism of endogenous adenosine?
Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1979;105(1):120-122
Inhibitory effect of adenosine on adrenergic neuroeffector transmission in the rabbit heart.
Hedqvist P; Fredholm BB
Journal article: ACTA PHYSIOLOGICA. 1978;104(4):469-478
INHIBITION OF ACETYLCHOLINE-RELEASE IN GUINEA-PIG ILEUM BY ADENOSINE
GUSTAFSSON L; HEDQVIST P; FREDHOLM BB; LUNDGREN G
Journal article: ACTA PHYSIOLOGICA. 1978;104(4):502-504
Morphine increases depolarization induced purine release from rat cortical slices.
Fredholm BB; Vernet L
Journal article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 1978;14(2):95-99
METABOLIC EFFECTS OF ORAL SALBUTAMOL IN LATE PREGNANCY
LUNELL NO; WAGER J; FREDHOLM BB; PERSSON B
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1978;64(2):239-245
Release of 3H-purines from [3H]-adenine labelled rabbit kidney following sympathetic nerve stimulation, and its inhibition by alpha-adrenoceptor blockage.
Fredholm BB; Hedqvist P
Journal article: FASEB JOURNAL. 1978;37(8):2181-2191
ERGOT DRUGS AND CENTRAL MONOAMINERGIC MECHANISMS - HISTOCHEMICAL, BIOCHEMICAL AND BEHAVIORAL-ANALYSIS
FUXE K; FREDHOLM BB; OGREN SO; AGNATI LF; HOKFELT T; GUSTAFSSON JA
Journal article: BRAIN RESEARCH. 1978;146(2):295-311
DOPAMINE RECEPTORS AND ERGOT DRUGS - EVIDENCE THAT AN ERGOLENE DERIVATIVE IS A DIFFERENTIAL AGONIST AT SUB-CORTICAL LIMBIC DOPAMINE RECEPTORS
FUXE K; FREDHOLM BB; AGNATI LF; CORRODI H
Journal article: DIABETOLOGIA. 1978;14(4):235-242
ACTIONS OF SALBUTAMOL IN LATE PREGNANCY - PLASMA CYCLIC-AMP, INSULIN AND C-PEPTIDE, CARBOHYDRATE AND LIPID METABOLITES IN DIABETIC AND NON-DIABETIC WOMEN
FREDHOLM BB; LUNELL NO; PERSSON B; WAGER J
Journal article: ACTA PHYSIOLOGICA. 1978;102(2):191-198
Effect of adenosine, adenosine analogues and drugs inhibiting adenosine inactivation on lipolysis in rat fat cells.
Fredholm BB
Journal article: PHARMACOLOGY. 1978;16:99-134
INTERACTION OF ERGOT DRUGS WITH CENTRAL MONO-AMINE SYSTEMS - EVIDENCE FOR A HIGH POTENTIAL IN TREATMENT OF MENTAL AND NEUROLOGICAL DISORDERS
FUXE K; FREDHOLM BB; AGNATI LF; OGREN SO; EVERITT BJ; JONSSON G; GUSTAFSSON JA
Journal article: ACTA ENDOCRINOLOGICA, SUPPLEMENT. 1978;88:27-56
PHARMACOLOGICAL AND BIOCHEMICAL EVIDENCE FOR DOPAMINE AGONISTIC EFFECT OF BROMOCRIPTINE
FUXE K; FREDHOLM BB; OGREN SO; AGNATI LF; HOKFELT T; GUSTAFSSON JA
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1978;42(1):23-34
INHIBITION OF NORADRENALINE-STIMULATED LIPOLYSIS AND CYCLIC-AMP ACCUMULATION IN ISOLATED RAT ADIPOCYTES BY PURIFIED PHOSPHOLIPASE C-TOXIN AND THETA-TOXIN FROM CLOSTRIDIUM-PERFRINGENS
FREDHOLM BB; MOLLBY R; ANDERSON P; MALMQUIST T; SMYTH CJ
Journal article: INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY. 1978;56(5):449-456
EFFECT OF IMMUNIZATION ON CYCLIC-AMP LEVEL AND THYMIDINE-H-3 INCORPORATION IN CULTURED LYMPHOID-CELLS
SANDBERG G; ERNSTROM U; NORDLIND K; FREDHOLM BB
Journal article: BIOCHEMICAL PHARMACOLOGY. 1978;27(24):2845-2850
Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5'-nucleotidase and adenosine deaminase.
Fredholm BB; Hedqvist P; Vernet L
Journal article: ACTA PHYSIOLOGICA. 1977;99(2):254-256
ANTILIPOLYTIC EFFECT OF ADENOSINE IN DOG ADIPOSE-TISSUE INSITU
FREDHOLM BB; SOLLEVI A
Journal article: ACTA CHIRURGICA SCANDINAVICA. 1977;143(1):9-14
CYCLIC-AMP AND METABOLIC SUBSTRATES IN HEMORRHAGIC-SHOCK OF RAT
FARNEBO LO; FREDHOLM BB; HAMBERGER B; HJEMDAHL P; WESTMAN L
Journal article: ACTA PHYSIOLOGICA. 1976;98(1):74-79
INFLUENCE OF ADIPOSE-TISSUE BLOOD-FLOW ON LIPOLYTIC RESPONSE TO CIRCULATING NORADRENALINE AT NORMAL AND REDUCED PH
HJEMDAHL P; FREDHOLM BB
Journal article: BIOCHEMICAL PHARMACOLOGY. 1976;25(14):1583-1588
Cyclic AMP independent inhibition by papaverine of histamine release induced by compound 48/80.
Fredholm BB; Guschin I; Elwin K; Schwab G; Uvnäs B
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1976;38(1):31-38
EFFECT OF SOME PHOSPHODIESTERASE INHIBITORS ON CENTRAL DOPAMINE MECHANISMS
FREDHOLM BB; FUXE K; AGNATI L
Journal article: ACTA PHYSIOLOGICA. 1976;97(3):319-324
INFLUENCE OF ACIDOSIS ON NORADRENALINE-INDUCED VASOCONSTRICTION IN ADIPOSE-TISSUE AND SKELETAL-MUSCLE
HJEMDAHL P; FREDHOLM BB
Journal article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1976;293(3):217-223
Effects of adenosine on adrenergic neurotransmission; prejunctional inhibition and postjunctional enhancement.
Hedqvist P; Fredholm BB
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1975;54(3):295-300
Indomethacin-induced increase in noradrenaline turnover in some rat organs.
Fredholm BB; Hedqvist P
Journal article: PEDIATRIC RESEARCH. 1975;9(1):26-30
DIPHENYLHYDANTOIN BINDING TO PROTEINS IN PLASMA AND ITS DEPENDENCE ON FREE FATTY-ACID AND BILIRUBIN CONCENTRATION IN DOGS AND NEWBORN-INFANTS
FREDHOLM BB; RANE A; PERSSON B
Journal article: ACTA PHYSIOLOGICA. 1975;93(1):52-58
SOME METABOLIC CONSEQUENCES OF ANAPHYLACTIC REACTION IN RABBIT
FREDHOLM BB; STRANDBERG K
Journal article: PEDIATRIC RESEARCH. 1975;9(1):26-30
Diphenylhydantoin Binding to Proteins in Plasma and Its Dependence on Free Fatty Acid and Bilirubin Concentration in Dogs and Newborn Infants
Fredholm BB; Rane A; Persson B
Journal article: BIOCHEMICAL PHARMACOLOGY. 1975;24(1):61-66
Indomethacin and the role of prostaglandins in adipose tissue.
Fredholm BB; Hedqvist P
Journal article: ACTA PHYSIOLOGICA. 1974;92(1):1-11
COMPARISON OF LIPOLYTIC-ACTIVITY OF CIRCULATING AND LOCALLY RELEASED NORADRENALINE DURING ACIDOSIS
HJEMDAHL P; FREDHOLM BB
Journal article: ACTA PHYSIOLOGICA. 1974;90(1):226-236
Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ.
Fredholm BB
Journal article: HORMONE AND METABOLIC RESEARCH. 1973;5(5):347-350
Actions of human chorionic somatomammotropin (HCS) in dog subcutaneous adipose tissue in situ.
Fredholm BB; Persson B
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1973;47(4):711-718
Role of pre- and postjunctional inhibition by prostaglandin E2 of lipolysis induced by sympathetic nerve stimulation in dog subcutaneous adipose tissue in situ.
Fredholm BB; Hedqvist P
Journal article: JOURNAL OF PHARMACY AND PHARMACOLOGY. 1972;24(5):378-382
Antagonism of prostaglandin F 2 induced bronchoconstriction and blood pressure changes by polyphloretin phosphate in the guinea-pig and cat.
Mathé AA; Strandberg K; Fredholm B
Journal article: ACTA PHYSIOLOGICA. 1970;80(4):567-576
Metabolic effects of prolonged sympathetic nerve stimulation in canine subcutaneous adipose tissue.
Fredholm BB; Karlsson J
Journal article: ACTA PHYSIOLOGICA. 1970;80(4):450-458
Effects of prostaglandin E1 in canine subcutaneous adipose tissue in situ.
Fredholm BB; Rosell S
Journal article: ACTA PHYSIOLOGICA. 1970;80(3):404-411
Fate of 3H-noradrenaline in canine subcutaneous adipose tissue.
Fredholm BB; Rosell S
Journal article: ACTA PHYSIOLOGICA. 1970;79(4):564-574
Effects of vasoactive drugs on circulation in canine subcutaneous adipose tissue.
Fredholm BB; Oberg B; Rosell S
Journal article: ACTA PHYSIOLOGICA. 1969;76(4):446-457
Release of histamine and formation of smooth-muscle stimulating principles in guinea-pig lung tissue induced by antigen and bee venom phosphatidase A.
Fredholm B; Strandberg K
Journal article: LIFE SCIENCES. 1968;7(21):1209-1215
Release of free fatty acids from canine subcutaneous adipose tissue by histamine and compound 48-80.
Fredholm BB; Meng HC; Rosell S
Journal article: ACTA PHYSIOLOGICA. 1968;74(s1):6a
Metabolic Effects of Prostaglandin E1 in Canine Adipose Tissue in situ
Fredholm BB; Rosell S
Journal article: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1967;25:28
Vascular reactions in canine subcutaneous adipose tissue following prostaglandin E1 (PGE1).
Fredholm BB; Oberg B; Rosell S
Journal article: LIFE SCIENCES. 1966;5(21):2023-2032
Influence of sympathetic nerve stimulation on noradrenaline stores in the rat salivary gland
Fredholm B; Sedvall G
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Low, but not high, dose caffeine is a readily available probe for adenosine actions
Fredholm BB; Yang J; Wang Y
Review: MOLECULAR ASPECTS OF MEDICINE. 2017;55:4-8
Pharmacological targeting of adenosine receptor signaling
Peleli M; Fredholm BB; Sobrevia L; Carlstrom M
Editorial comment: MOLECULAR ASPECTS OF MEDICINE. 2017;55:1-3
Adenosine - from molecular mechanisms to pathophysiology
Sobrevia L; Fredholm BB
Book chapter: COFFEE IN HEALTH AND DISEASE PREVENTION. 2015;p. 831-834
Chapter 91 Adenosine Receptors as the Biochemical Target for Low Doses of Caffeine
Fredholm BB
Conference publication: PURINERGIC SIGNALLING. 2014;10(4):733
Energy homeostasis in mice lacking adenosine receptors
Wang Y; Urmalia V; Bjornholm M; Winerdal M; Carlstrom M; Fredholm BB
Conference publication: HYPERTENSION. 2014;64
Adenosine A3 Receptors Regulate Oxidative Stress And Inflammatory Responses In A Model Of Hypertension And Renal Disease
Yang T; Hezel M; Peleli M; Zhang X; Terrando N; Fredholm B; Carlstrom M
Conference publication: DIABETES. 2014;63:A560
Abrogation of Adenosine A1 Receptor Signaling Improves Metabolic Regulation in Aging and Obesity
Gao X; Sandberg M; Fredholm B; Persson E; Jansson L; Carlstrom M
Review: NATURE REVIEWS DRUG DISCOVERY. 2013;12(4):265-286
Adenosine receptors as drug targets - what are the challenges?
Chen J-F; Eltzschig HK; Fredholm BB
Conference publication: DIABETES. 2013;62:A480-A481
Adenosine A1 Receptor Deficiency Improves Glucose Metabolism and Attenuates Vasoconstriction of Islet Arterioles to Angiotensin II
Gao X; Sandberg M; Fredholm B; Persson AEG; Jansson L; Carlstrom M
Book chapter: ADENOSINE. 2013;p. 3-19
Adenosine and Metabolism—A Brief Historical Note
Fredholm BB
Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(16):5913-5914
Rethinking the purinergic neuron-glia connection
Fredholm BB
Conference publication: FASEB JOURNAL. 2012;26:690.3
Role of Adenosine A1 Receptors in Regulation of Arteriolar Responses to Adenosine and Angiotensin II
Gao X; Carlstrom M; Fredholm B; Persson E
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S183
Brain adenosine and the actions of caffeine
Fredholm BB
Review: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2011;11(8):973-1011
Adenosine and ATP Receptors in the Brain
Burnstock G; Fredholm BB; Verkhratsky A
Review: PHARMACOLOGICAL REVIEWS. 2011;63(1):1-34
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors-An Update
Fredholm BB; IJzerman AP; Jacobson KA; Linden J; Mueller CE
Review: SLEEP AND BIOLOGICAL RHYTHMS. 2011;9:24-28
Physiological and pathophysiological roles of adenosine
Fredholm BB
Review: ADVANCES IN PHARMACOLOGY. 2011;61:77-94
Adenosine and the regulation of metabolism and body temperature.
Fredholm BB; Johansson S; Wang Y-Q
Published conference paper: JOURNAL OF NEUROIMMUNOLOGY. 2010;224(1-2):85-92
CX₃CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes
Piccinin S; Di Angelantonio S; Piccioni A; Volpini R; Cristalli G; Fredholm BB; Limatola C; Eusebi F; Ragozzino D
Review: CELL DEATH AND DIFFERENTIATION. 2010;17(7):1071-1082
Adenosine signaling and function in glial cells
Boison D; Chen J-F; Fredholm BB
Review: ACTA PHYSIOLOGICA. 2010;199(2):93-147
The birth and postnatal development of purinergic signalling
Burnstock G; Fredholm BB; North RA; Verkhratsky A
Editorial comment: ACTA PHYSIOLOGICA. 2010;199(2):91-92
Purines-80 years and very much alive
Fredholm B; Verkhratsky A
Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1284-1288
Adenosine receptors as drug targets
Fredholm BB
Review: PARKINSONISM & RELATED DISORDERS. 2009;15(6):406-413
Adenosine, adenosine A_2A antagonists, and Parkinson's disease
Jenner P; Mori A; Hauser R; Morelli M; Fredholm BB; Chen JF
Other: HETEROCYCLES. 2009;79(1):73-83
Adenosine Receptors: The Contributions by John W. Daly
Fredholm BB; Jacobson KA
Conference publication: JOURNAL OF PHYSIOLOGICAL SCIENCES. 2009;59:436
HIGH-PROTEIN INDUCED GLOMERULAR HYPERFILTRATION IS INFLUENCED BY NITRIC OXIDE BUT IS INDEPENDENT OF THE TUBULOGLOMERULAR FEEDBACK MECHANISM
Sallstrom J; Fredholm BB; Sandler S; Carlstrom M; Persson EG
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2008;58(9):S778
Methotrexate (MTX), ethanol and the liver; Adenosine and its receptors play a central role 2 in fatty liver
Peng Z; Wilder T; Blackburn MT; Fredholm B; Cronstein BN
Conference publication: DIABETOLOGIA. 2008;51:S195
Adenosine A, receptors modulate glucose-induced pulses of islet hormone release
Salehi A; Parandeh F; Fredholm B; Grapengiesser E; Hellman B
Conference publication: PURINERGIC SIGNALLING. 2008;4:S173
Adenosine and osteoporosis: Adenosine A1 receptor blockade reverses bone loss in ovariectomized mice and deletion of adenosine A2A receptors leads to diminished bone density
Kara F; Doty S; Boskey A; Fredholm B; Goldring S; Zaidi M; Cronstein B
Conference publication: PURINERGIC SIGNALLING. 2008;4:S82-S83
Adenosine and its receptors play a central role in ethanol-induced fatty liver
Zhongsheng P; Wilder T; Blackburn M; Fredholm B; Cronstein B
Conference publication: PURINERGIC SIGNALLING. 2008;4:S1-S2
Adenosine - an endogenous distress signal
Fredholm BB
Published conference paper: PROGRESS IN NEUROBIOLOGY. 2007;83(5):263-276
Aspects of the general biology of adenosine A_2A signaling
Fredholm BB; Chern Y; Franco R; Sitkovsky M
Review: CELL DEATH AND DIFFERENTIATION. 2007;14(7):1315-1323
Adenosine, an endogenous distress signal, modulates tissue damage and repair
Fredholm BB
Published conference paper: ACTA PHYSIOLOGICA. 2007;190(1):87-96
Eliminating the antilipolytic adenosine A₁ receptor does not lead to compensatory changes in the antilipolytic actions of PGE₂ and nicotinic acid
Johansson SM; Yang J-N; Lindgren E; Fredholm BB
Published conference paper: ACTA PHYSIOLOGICA. 2007;190(1):63-75
Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A₁ receptors
Yang J-N; Tiselius C; Dare E; Johansson B; Valen G; Fredholm BB
Published conference paper: ACTA PHYSIOLOGICA. 2007;190(1):3-7
G-protein-coupled receptors:: an update
Fredholm BB; Hokfelt T; Milligan G
Editorial comment: ACTA PHYSIOLOGICA. 2007;190(1):1
A Nordic meeting on G-protein-coupled receptors: from molecular aspects to novel therapy
Schulte G; Fredholm B
Editorial comment: CURRENT OPINION IN PHARMACOLOGY. 2007;7(1):1-2
Many ways to Rome - multiple approaches to novel drugs
Chergui K; Fredholm BB; Svenningsson P
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2007;22:S36
Adenosine and osteoporosis:: Adenosine A₁ receptor blockade reverses bone loss in ovariectomized mice and deletion of adenosine A_2A receptors leads to diminished bone density
Kara FM; Doty SB; Boskey A; Fredholm B; Cronstein BN
Conference publication: NEURON GLIA BIOLOGY. 2007;2:S56
Protective function of adenosine A₁ and A_2A receptors from damage after hypoxia or neurotoxicants in primary astrocytes
Karovic O; Tonazzini I; Fredholm B; Dare E
Conference publication: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2007;27(6):E130
Postischemic neovascularization is modulated by the A₁ adenosine receptor
Mirza A; Karaoli T; Fredholm B; Tucker AL
Book chapter: ADENOSINE RECEPTORS. 2006;p. 143-155
Adenosine, Adenosine Receptors, and the Regulation of Glial Cells in Neuronal Damage
Fredholm B; Schulte G; Färber K; Daré E
Published conference paper: ANESTHESIOLOGY. 2006;104(4):724-733
Activation and inhibition of human muscular and neuronal nicotinic acetylcholine receptors by succinylcholine
Jonsson M; Dabrowski M; Gurley DA; Larsson O; Johnson EC; Fredholm BB; Eriksson LI
Conference publication: DIABETOLOGIA. 2006;49:652-653
Diabetes-induced hyperfiltration in adenosine A1-receptor deficient mice lacking the tubuloglomerular feedback mechanism
Sallstrom J; Carlsson P-O; Fredholm B; Larsson E; Persson AEG; Palm F
Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:304
Characterization of the role of the adenosine A1 receptor (A1R) in metabolism using A1R knock-out (-/-) mice
Johansson S; Salehi A; Sandstrom M; Lundquist I; Carlsson P-O; Westerblad H; Katz A; Fredholm B
Conference publication: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2006;248(1-2):297
Adenosine interactions with dopaminergic transmission mediated by A1 and A2A receptors
Fredholm BB; Svenningsson P; Chergui K
Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:362-363
Consequences of cobalt chloride induced stabilization of HIF-1α in primary cultures of mouse astrocytes
Karovic O; Rebola N; Edström E; Lövdahl C; Fredholm BB; Daré E
Conference publication: ARTHRITIS & RHEUMATOLOGY. 2006;54(9):S511-S512
Adenosine A₁ receptors (A₁R) play a critical role in osteoclast formation.
Kara FM; Doty SB; Boskey A; Fredholm B; Cronstein BN
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2006;21:S166
Adenosine at receptor regulate osteoclasts function and formation in vitro and in vivo.
Kara FM; Doty SB; Boskey A; Fredholm B; Cronstein BN
Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:26
Targeting adenosine receptors
Fredholm BB
Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:182
Cardiovascular characterization of the adenosine A1 receptor knock-out mouse
Yang J; Tiselius C; Bian Z; Lövdahl C; Daré E; Edström E; Johansson B; Thorén P; Valen G; Fredholm BB
Editorial comment: LIFE SCIENCES. 2005;78(1):1
Untitled
Fredholm B; Porreca F
Review: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. 2005;45:385-412
Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs.
Fredholm BB; Chen J-F; Masino SA; Vaugeois J-M
Published conference paper: JOURNAL OF MOLECULAR NEUROSCIENCE. 2005;26(2-3):239-244
Adenosine-dopamine interactions revealed in knockout mice
Salmi P; Chergui K; Fredholm BB
Review: INTERNATIONAL REVIEW OF NEUROBIOLOGY. 2005;63:191-270
Adenosine and brain function
Fredholm BB; Chen JF; Cunha RA; Svenningsson P; Vaugeois JM
Conference publication: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 2005;32(7):A11
The influence of adenosine A1-receptors on blood pressure regulation and renin release
Brown R; Fredholm B; Thorén P; Persson E
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2004;14:s156-s157
Caffeine as an adenosine receptor antagonist
Fredholm BB
Review: LAKARTIDNINGEN. 2004;101(34):2552-2555
[Connection between caffeine, adenosine receptors and dopamine. Coffee reduces the risk of Parkinson disease].
Fredholm BB
Editorial comment: TRENDS IN PHARMACOLOGICAL SCIENCES. 2004;25(4):170-171
Borje Uvnas and the rise of modern pharmacology
Fredholm B
Other: NEUROLOGY. 2003;61(11 Suppl 6):S10-S11
Exciting news about A2A receptors.
Svenningsson P; Fredholm BB
Review: NEUROLOGY. 2003;61(11 Suppl 6):S5-S9
Adenosine-dopamine interactions: development of a concept and some comments on therapeutic possibilities.
Fredholm BB; Svenningsson P
Published conference paper: EXPERIMENTAL CELL RESEARCH. 2003;290(1):168-176
The G_S-coupled adenosine A_2B receptor recruits divergent pathways to regulate ERK1/2 and p38
Schulte G; Fredholm BB
Review: CELLULAR SIGNALLING. 2003;15(9):813-827
Signalling from adenosine receptors to mitogen-activated protein kinases
Schulte G; Fredhohn BB
Published conference paper: DRUG DEVELOPMENT RESEARCH. 2003;58(4):428-438
Adenosine A₃ receptors in the rat hippocampus:: Lack of interaction with A₁ receptors
Lopes LV; Rebola N; Costenla AR; Halldner L; Jacobson MA; Oliveira CR; Richardson PJ; Fredholm BB; Ribeiro JA; Cunha RA
Published conference paper: DRUG DEVELOPMENT RESEARCH. 2003;58(4):350-353
Consequences of eliminating adenosine A₁ receptors in mice
Fredholm BB; Halldner L; Johansson C; Schulte G; Lövdahl C; Thorén P; Dunwiddie TV; Masino SA; Poelchen W; Diao LH; Illes P; Zahniser NR; Valen G; Tokuno S; Sommerschild H; Giménez-Llort L; Fernández-Teruel A; Escorihuela RM; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Herlenius E; Pekny S; Gebré-Medhin S; Brown R; Ollerstam A; Persson AEG; Skott O; Johansson B
Review: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2003;3(4):413-426
Pharmacology of adenosine A_2A receptors and therapeutic applications
Fredholm BB; Cunha RA; Svenningsson P
Published conference paper: MOLECULAR PHARMACOLOGY. 2002;62(5):1137-1146
Signaling pathway from the human adenosine A₃ receptor expressed in chinese hamster ovary cells to the extracellular signal-regulated kinase 1/2
Schulte G; Fredholm BB
Meeting abstract: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2002;34(6):A59
A1 receptors mediate delayed remote preconditioning, possible involvement of MAPK
Sommershild HT; Fredholm BB; Schulte G; Jägerbrink T; Lövdahl C; Tokuno S; Valen G
Review: LAKARTIDNINGEN. 2002;99(14):1604-1608
[The passion concerning behavior of human beings. The intensive sociology debate and some lessons learned from it].
Fredholm BB
Published conference paper: CELLULAR SIGNALLING. 2002;14(2):109-113
Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists
Schulte G; Fredholm BB
Conference publication: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. 2002;29(8):A88
In a model of delayed remote preconditioning the adenosine A1 receptor mediates protection, without change in MAP kinase signalling
Sommerschild HT; Schulte G; Tokuno S; Lövdahl C; Fredholm BB; Valen BB
Conference publication: DRUG DEVELOPMENT RESEARCH. 2002;56(4):572
Sperm capacitation in adora₁ KO mice
Liguori L; Bellezza I; Nucciarelli F; Johansson B; Fredholm B; Minelli A
Review: PHARMACOLOGICAL REVIEWS. 2001;53(4):527-552
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.
Fredholm BB; IJzerman AP; Jacobson KA; Klotz KN; Linden J
Other: TRENDS IN PHARMACOLOGICAL SCIENCES. 2001;22(11):596
Thomas V. Dunwiddie (1951-2001) - Obituary
Fredholm BB
Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2001;55(2):97
The effects of adenosine and caffeine on locomotor activity are mediated via DARPP-32 phosphorylation
Lindskog M; Svenningsson P; Fienberg A; Bibb J; Greengard P; Fredholm B; Fisone G
Conference publication: SLEEP. 2001;24:A43
An absence of adenosine effects in laterodorsal tegmental neurons of A1R knockout mice associated with increased wakefulness
Arrigoni E; Kaushul N; Johansen B; Fredholm B; Halldner L; Greene RW
Published conference paper: DRUG DEVELOPMENT RESEARCH. 2001;52(1-2):274-282
Adenosine receptor signaling in vitro and in vivo
Fredholm BB; Arslan G; Halldner L; Kull B; Schulte G; Ådén U; Svenningsson P
Review: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 2000;362(4-5):364-374
Structure and function of adenosine receptors and their genes
Fredholm BB; Arslan G; Halldner L; Kull B; Schulte G; Wasserman W
Review: LAKARTIDNINGEN. 1999;96(50):5639-5644
[Vademecum of a biomedical researcher: from the foundation of science to the threat from post-modern "nonsense"].
Fredholm BB
Review: PROGRESS IN NEUROBIOLOGY. 1999;59(4):355-396
Distribution, biochemistry and function of striatal adenosine A_2A receptors
Svenningsson P; Le Moine C; Fisone G; Fredholm BB
Review: PHARMACOLOGICAL REVIEWS. 1999;51(1):83-133
Actions of caffeine in the brain with special reference to factors that contribute to its widespread use.
Fredholm BB; Bättig K; Holmén J; Nehlig A; Zvartau EE
Letter: NEUROSCIENCE. 1999;88(4):1005-1008
Activation of dopamine D₂ receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms
Lindskog M; Svenningsson P; Fredholm BB; Greengard P; Fisone G
Published conference paper: NEUROSCIENCE FOR ADDICTION MEDICINE: FROM PREVENTION TO REHABILITATION - CONSTRUCTS AND DRUGS. 1999;120:301-310
Adenosine and P2 receptors in PC12 cells. Genotypic, phenotypic and individual differences.
Arslan G; Fredholm BB
Published conference paper: DRUG DEVELOPMENT RESEARCH. 1998;45(3-4):324-328
Locating the neuronal targets for caffeine
Fredholm BB; Arslan G; Kull B; Svenningsson P
Letter: TRENDS IN PHARMACOLOGICAL SCIENCES. 1998;19(2):46-48
Striatal adenosine A_2A receptors -: where are they?: What do they do?
Fredholm BB; Svenningsson P
Conference publication: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1998;358(1):R125
Functional interactions between adenosine A_2A and dopamine D₂ receptors co-transfected in CHO cells.
Kull B; Ferré S; Arslan G; Svenningsson P; Fuxe K; Owman C; Fredholm BB
Conference publication: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 1998;358(1):R123
Activation of protein kinase C increases NECA induced cyclic AMP production in Chinese hamster ovary cells stably transfected with the human adenosine A_2A or A_2B receptor
Schulte G; Fredholm BB
Review: TRENDS IN NEUROSCIENCES. 1997;20(10):482-487
Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
Ferre S; Fredholm BB; Morelli M; Popoli P; Fuxe K
Review: NEUROSCIENCE. 1997;80(4):1187-1207
Distribution and postnatal ontogeny of adenosine A(2A) receptors in rat brain: Comparison with dopamine receptors
Johansson B; Georgiev V; Fredholm BB
Published conference paper: NEUROPHARMACOLOGY. 1997;36(9):1319-1326
Down-regulation of adenosine A2A receptors upon NGF-induced differentiation of PC12 cells.
Arslan G; Kontny E; Fredholm BB
Published conference paper: NEUROPHARMACOLOGY. 1997;36(9):1327-1338
Neonatal cerebral hypoxia-ischemia: The effect of adenosine receptor antagonists
Bona E; Aden U; Gilland E; Fredholm BB; Hagberg H
Published conference paper: NEUROPHARMACOLOGY. 1997;36(9):1309-1317
Caffeine mimics the effect of a dopamine D-2/3 receptor agonist on the expression of immediate early genes in globus pallidus
Svenningsson P; Fredholm BB
Review: GENERAL PHARMACOLOGY: THE VASCULAR SYSTEM. 1997;28(3):345-350
Purines and neutrophil leukocytes.
Fredholm BB
Review: INTERNATIONAL REVIEW OF NEUROBIOLOGY. 1997;40:259-280
Adenosine and neuroprotection.
Fredholm BB
Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 1997;120:P304
Further characterisation of adenosine A(2A) receptor antagonist radioligand [H-1]-SCH 58261: Studies on the human cloned A(2A) receptor
Dionisotti S; Ongini E; Zocchi C; Molta C; Kull B; Arslan G; Fredholm BB
Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 1997;38(4):3820
Localization of adenosine receptor messenger RNAs in the rat eye.
Kvanta A; Seregard S; Sejersen S; Kull B; Fredholm BB
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 1996;17(10):364-372
Pharmacology of adenosine A2A receptors.
Ongini E; Fredholm BB
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 1996;17(3):108-113
Adenosine receptor ligands: differences with acute versus chronic treatment.
Jacobson KA; von Lubitz DK; Daly JW; Fredholm BB
Conference publication: FASEB JOURNAL. 1996;10(3):782
Spinal adenosine receptors: Autoradiography using A1 and A2 adenosine receptor selective ligands
DeLander GE; Lindstrom K; Fredholm BB
Other: BIOCHEMICAL SOCIETY TRANSACTIONS. 1995;23(3):453S
Protein kinase C isoform expression and ATP response change with smooth muscle cell differentiation.
Assender JW; Irenius E; Fredholm BB
Review: LAKARTIDNINGEN. 1995;92(16):1662-1664
[Hirschsprung disease. A receptor defect].
Fredholm BB
Review: LAKARTIDNINGEN. 1995;92(14):1459-1467
[Growth factors--clarification of their mechanism].
Fredholm BB; Heldin CH
Book chapter: PHARMACOLOGICAL SCIENCES: PERSPECTIVES FOR RESEARCH AND THERAPY IN THE LATE 1990S. 1995;p. 295-302
Role of Purines in the Central Nervous System
White TD; Ribeiro JA; Edwards FA; Fredholm BB; Phillis JW
Book chapter: ADENOSINE AND ADENINE NUCLEOTIDES: FROM MOLECULAR BIOLOGY TO INTEGRATIVE PHYSIOLOGY. 1995;p. 499-507
Evidence for the existence of antagonistic intramembrane adenosine A(2a)/dopamine D-2 receptor interactions in the basal ganglia: Analysis from the network to the molecular level
FUXE K; FERRE S; DASGUPTA S; OCONNOR WT; SNAPRUD P; ARENAS E; PERSSON H; UNGERSTEDT U; FREDHOLM B
Conference publication: FASEB JOURNAL. 1995;9(3):A89
IMMEDIATE-EARLY GENE (IEG) AND NEUROPEPTIDE MESSENGER-RNA EXPRESSION IN CHRONIC PAIN
DELANDER GE; SCHOTT E; BRODIN E; FREDHOLM BB
Published conference paper: ZOOLOGICAL STUDIES. 1995;34:191-194
A SENSITIVE METHOD FOR MEASUREMENTS OF LUMINESCENCE IN SINGLE CELLS
KOHLER M; NORGREN S; FREDHOLM BB; LARSSON O; LUTHMAN H; BERGGREN PO
Conference publication: BRITISH JOURNAL OF PHARMACOLOGY. 1994;112:U72
EXPRESSION AND LOCALIZATION OF THE A(2A) ADENOSINE RECEPTOR IN THE HIPPOCAMPUS OF THE RAT
CUNHA RA; JOHANSSON B; SEBASTIAO AM; RIBEIRO JA; FREDHOLM BB
Conference publication: DRUG DEVELOPMENT RESEARCH. 1993;28(3):374-380
ANTAGONISTIC A2A/D2 RECEPTOR INTERACTIONS IN THE STRIATUM AS A BASIS FOR ADENOSINE/DOPAMINE INTERACTIONS IN THE CENTRAL-NERVOUS-SYSTEM
FUXE K; FERRE S; SNAPRUD P; VONEULER G; JOHANSSON B; FREDHOLM B
Other: CIBA FOUNDATION SYMPOSIUM. 1992;164:197
GENERAL DISCUSSION-1 - THE METABOTROPIC GLUTAMATE RECEPTOR
AKAIKE N; TANAKA C; MIKOSHIBA K; TSIEN RW; NISHIZUKA Y; DALY JW; FREDHOLM B
Conference publication: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 1991;10(5):1145-1147
AUTORADIOGRAPHICAL STUDIES OF INVITRO AND CHRONIC INVIVO EFFECTS OF PROPENTOFYLLINE ON ADENOSINE-A1 AND ADENOSINE-A2 RECEPTORS AND NBMPR-SENSITIVE NUCLEOSIDE TRANSPORTERS
PARKINSON FE; JOHANSSON B; RUDOLPHI K; FREDHOLM BB
Book chapter: PRESYNAPTIC RECEPTORS AND NEURONAL TRANSPORTERS. 1991;p. 249-252
Mechanisms of Inhibition of Transmitter Release by Adenosine Analogs
Fredholm BB; Hu P-S; van der Ploeg I; Dunér-Engström M; Dunwiddie TV
Conference publication: EUROPEAN JOURNAL OF PHARMACOLOGY. 1990;183(6):2171
DISTRIBUTION OF PERTUSSIS TOXIN IN THE RAT-BRAIN AFTER INJECTION INTO THE LATERAL CEREBRAL-VENTRICLES
VANDERPLOEG I; DUARTECINTRA A; FUXE K; ASKELOF P; PARKINSON F; FREDHOLM BB
Conference publication: EUROPEAN JOURNAL OF PHARMACOLOGY. 1990;183(6):2136-2137
AUTORADIOGRAPHICAL STUDIES OF THE EFFECTS OF MG++ AND GTP ON AGONIST BINDING TO ADENOSINE-A1 AND ADENOSINE-A2 RECEPTORS IN RAT-BRAIN
PARKINSON FE; FASTBOM J; FREDHOLM BB
Conference publication: KIDNEY INTERNATIONAL. 1990;37(1):217
G-PROTEIN SUBUNITS DISTRIBUTION IN THE LUMINAL AND BASOLATERAL MEMBRANE OF PROXIMAL TUBULAR CELL
VANDERPLOEG I; CELSI G; BERTORELLO A; HOLTBACK U; FREDHOLM B; APERIA A
Book chapter: PURINES IN CELLULAR SIGNALING. 1990;p. 184-193
Mechanisms of Adenosine Action
Fredholm BB; Fastbom J; Dunér-Engström M; Hu P-S; van der Ploeg I; Altiok N; Gerwins P; Kvanta A; Nordstedt C
Conference publication: PEDIATRIC RESEARCH. 1987;21(4):219
BREATHING RESPONSE TO HYPOXIA IN RELATION TO MEASURED PLASMA NEUROMODULATORS DURING POSTNATAL-DEVELOPMENT
MOSS IR; RUNOLD M; DAHLIN I; YAMAMOTO Y; FREDHOLM BB; NYBERG F; LAGERCRANTZ H
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS: WENNER-GREN SYMPOSIUM. 1987;p. 222-235
On the Role of Receptor-Receptor Interactions in Synaptic Transmission: Biochemical and Autoradiographical Studies on the Interactions between α2-adrenergic and Neuropeptide Y Receptors in the Nucleus Tractus Solitarius
Fuxe K; Agnati LF; Härfstrand A; Fredholm BB; Kalia M; Goldstein M
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS: WENNER-GREN CENTER INTERNATIONAL SYMPOSIUM SERIES. 1987;p. 222-235
On the Role of Receptor-Receptor Interactions in Synaptic Transmission: Biochemical and Autoradiographical Studies on the Interactions between α2-adrenergic and Neuropeptide Y Receptors in the Nucleus Tractus Solitarius
Fuxe K; Agnati LF; Härfstrand A; Fredholm BB; Kalia M; Goldstein M
Book chapter: TOPICS AND PERSPECTIVES IN ADENOSINE RESEARCH. 1987;p. 509-520
Interactions Between the Neuromodulator Adenosine and the Classic Transmitters
Fredholm BB; Dunér-Engstrom M; Fastbom J; Jonzen B; Lindgren E; Nordstedt C; Pedata F; van der Ploeg I
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS: WENNER-GREN CENTER INTERNATIONAL SYMPOSIUM SERIES. 1987;p. 308-317
Interactions between the Modulator Adenosine and Classical Transmitters
Fredholm BB; Nordstedt C; van der Ploeg I; Lindgren E; Ng J; Jondal M
Book chapter: RECEPTOR-RECEPTOR INTERACTIONS: WENNER-GREN SYMPOSIUM. 1987;p. 308-317
Interactions between the Modulator Adenosine and Classical Transmitters
Fredholm BB; Nordstedt C; van der Ploeg I; Lindgren E; Ng J; Jondal M
Conference publication: EARLY HUMAN DEVELOPMENT. 1986;14(2):134-135
HYPOXIC DEPRESSION OF RESPIRATION IN NEONATES MEDIATED BY ADENOSINE
LAGERCRANTZ H; RUMOLD M; DAHLIN I; FREDHOLM BB; MOSS I
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1986;59:48
ADENOSINE EFFECTS IN HUMAN-BLOOD PLATELETS - RELATIONSHIP BETWEEN DRUG DISAPPEARANCE AND EFFECT KINETIC
SODERBACK U; SOLLEVI A; FREDHOLM BB
Conference publication: PEDIATRIC RESEARCH. 1985;19(7):777
RELEASE OF ADENOSINE FROM THE ISCHEMIC HUMAN-HEART
SOLLEVI A; KAIJSER L; FREDHOLM BB
Conference publication: PEDIATRIC RESEARCH. 1985;19(4):175
RESPIRATORY EFFECTS OF AN ADENOSINE ANALOG AND THEOPHYLLINE IN NONANESTHETIZED RABBIT PUPS
LAGERCRANTZ H; RUNOLD M; FREDHOLM B
Conference publication: ACTA PHYSIOLOGICA. 1985;123(2):A54
THE EFFECT OF AN ADENOSINE ANALOG ON RESPIRATION DURING DEVELOPMENT
RUNOLD M; LAGERCRANTZ H; FREDHOLM BB
Conference publication: ACTA PHYSIOLOGICA. 1985;124:250
AUTONOMIC MECHANISMS UNDERLYING CAPSAICIN INDUCED ORAL SENSATIONS AND SALIVATION IN MAN
DUNERENGSTROM M; FREDHOLM BB; LARSSON O; LUNDBERG JM; SARIA A
Book chapter: METHODS USED IN ADENOSINE RESEARCH. 1985;p. 337-357
Methods Used to Study the Involvement of Adenosine in the Regulation of Lipolysis
Fredholm BB
Book chapter: KONGREß DER DEUTSCHEN GESELLSCHAFT FÜR CHIRURGIE MÜNCHEN, 10.–13. APRIL 1985: DEUTSCHE GESELLSCHAFT FÜR CHIRURGIE. 1985;p. 59-62
Die Bedeutung von Sauerstoffradikalen in der Pathogenese postischämischer Gewebeschäden
Schoenberg MH; Younes M; Haglund U; Fredholm BB; Schildberg FW
Conference publication: ACTA PHYSIOLOGICA. 1984;120(2):A11
CARDIOVASCULAR EFFECTS OF ADENOSINE IN MAN
SOLLEVI A; FREDHOLM BB; LAGERKRANSER M; IRESTEDT L; GORDON E
Conference publication: ACTA PHYSIOLOGICA. 1984;120(2):A32
HYPOTENSIVE AND HYPOTHERMIC EFFECTS OF ADENOSINE DERIVATIVES
JONZON B; BERGQUIST A; FREDHOLM BB
Conference publication: CELL AND TISSUE KINETICS. 1984;17(3):300
STUDIES ON PROLIFERATING THYMOCYTES IN GUINEA-PIGS
SANDBERG G; SODER O; FREDHOLM BB; ERNSTROM U; KOLARE S
Book chapter: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1984;p. 547
The effect of dipyridamole on plasma adenosine levels and skin micro-circulation in man.
Sollevi A; Ostergren J; Hjemdahl P; Fredholm BB; Fagrell B
Conference publication: LANGENBECKS ARCHIV F�R CHIRURGIE. 1983;361:716-717
CHANGES IN THE ACID-BASE STATUS, LACTATE AND PURINE METABOLISM DURING RECONSTRUCTIVE AORTIC-SURGERY
SCHOENBERG M; FREDHOLM B; HOHLBACH G
Conference publication: NEONATOLOGY. 1983;43(5-6):298-299
ADENOSINE-ANALOGS PRODUCE APNEA ANTAGONIZED BY THEOPHYLLINE IN RABBIT NEONATES AND KITTENS
LAGERCRANTZ H; YAMAMOTO Y; RUNOLD M; PRABHAKAR N; FREDHOLM BB; VANEULER C
Conference publication: THROMBOSIS AND HAEMOSTASIS. 1983;50(1):20
DIPYRIDAMOLE TREATMENT DOUBLES THE PLASMA ADENOSINE LEVEL IN PATIENTS WITH MINOR STROKE
SOLLEVI A; LINK H; FREDHOLM BB
Conference publication: INTERNATIONAL JOURNAL OF MICROCIRCULATION-CLINICAL AND EXPERIMENTAL. 1983;2(4):352-353
FURTHER EVIDENCE FOR THE INVOLVEMENT OF FREE-RADICALS IN THE PATHOGENESIS OF THE ISCHEMIC DAMAGE OF THE SMALL-INTESTINE
SCHOENBERG MH; JUNG H; YOUNES M; HAGLUND U; FREDHOLM B; SELLIN D; SCHILDBERG FW
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1983;18(1):72
INCREASED INTRACELLULAR LEVEL OF CYCLIC-AMP REDUCES TARGET BINDING OF HUMAN NK-CELLS
ULLBERG M; JONDAL M; LANEFELT F; FREDHOLM BB
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1982;51:24
ADENOSINE AND CYCLIC-AMP IN THE RAT HIPPOCAMPUS
JONZON B; LINDSTROM K; FREDHOLM BB
Conference publication: JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY. 1982;20(6):420-421
THE EFFECT OF DIPYRIDAMOLE ON PLASMA ADENOSINE LEVELS AND SKIN MICRO-CIRCULATION IN MAN
SOLLEVI A; OSTERGREN J; HJEMDAHL P; FREDHOLM BB; FAGRELL B
Conference publication: ACTA PHYSIOLOGICA. 1982;:34
EFFECTS OF SOME NEUROACTIVE SUBSTANCES ON VENTILATION IN NEWBORN RABBITS
YAMAMOTO Y; LAGERCRANTZ H; FREDHOLM B; VONEULER C
Conference publication: INTERNATIONAL JOURNAL OF MICROCIRCULATION-CLINICAL AND EXPERIMENTAL. 1982;1(3):296
FREE-RADICALS INVOLVEMENT IN THE ISCHEMIC DAMAGE OF THE SMALL-INTESTINE
MUHL E; SCHOENBERG M; HAGLUND U; SELLIN D; YOUNES M; FREDHOLM B; SCHILDBERG FW
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1982;51:25
INCREASE OF INTRACELLULAR LEVELS OF CYCLIC-AMP IN HUMAN NATURAL-KILLER CELLS INHIBITS TARGET-CELL RECOGNITION
LANEFELT F; ULLBERG M; JONDAL M; FREDHOLM BB
Book chapter: NK CELLS AND OTHER NATURAL EFFECTOR CELLS. 1982;p. 607-614
INCREASE IN INTRA-CELLULAR LEVELS OF CYCLIC AMP INHIBITS TARGET CELL RECOGNITION BY HUMAN NK CELLS
Ullberg M; Jondal M; Klein G; Lanefeldt F; Fredholm BB
Book chapter: NK CELLS AND OTHER NATURAL EFFECTOR CELLS. 1982;p. 631-637
PRESENCE OF FcR FOR IgG AND IgM ON HUMAN NK CELLS: THE ROLE OF IMMUNE COMPLEXES IN THE REGULATION OF NK CELL CYTOTOXICITY
Merrill JE; Golub S; Jondal M; Lanefeldt F; Fredholm B
Conference publication: ACTA PHYSIOLOGICA. 1982;:31
CHARACTERIZATION OF ADENOSINE RECEPTORS IN THE BRAIN
FREDHOLM BB; LINDGREN E
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1981;49:20
ADENOSINE AND ADIPOSE-TISSUE
FREDHOLM BB; SOLLEVI A
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1981;49:18-19
CHARACTERIZATION OF ADENOSINE-RECEPTORS MEDIATING CYCLIC-AMP ELEVATION IN THE RAT HIPPOCAMPUS
FREDHOLM BB; JONZON B; LINDSTROM K
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1981;49:59
SYMPATHETIC-NERVE STIMULATION RELEASES ADENINE-NUCLEOTIDES AND NUCLEOSIDES FROM THE PERFUSED RABBIT HEART
FREDHOLM BB; HEDQVIST P; LINDSTROM K; WENNMALM M
Conference publication: ACTA PHYSIOLOGICA. 1981;112(2):A8
EVIDENCE THAT ADENOSINE REGULATES INTERICTAL SPIKE ACTIVITY IN THE HIPPOCAMPUS
FREDHOLM BB; DUNWIDDIE T; HOFFER B; LINDSTROM K
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1981;49:16-17
ROTATION BEHAVIOR INDUCED BY METHYLXANTHINES - PHOSPHODIESTERASE INHIBITION, ADENOSINE ANTAGONISM OR SOME UNKNOWN MECHANISM OF ACTION
FREDHOLM BB; HERRERAMARSCHITZ M; UNGERSTEDT U
Book chapter: HOMEOSTASIS IN INJURY AND SHOCK. 1981;p. 71-80
SYMPATHO-ADRENAL AND LOCAL CONTROL OF ADIPOSE TISSUE FUNCTION IN INJURY AND SHOCK
Fredholm BB
Book chapter: HOMEOSTASIS IN INJURY AND SHOCK. 1981;p. 207-208
CATECHOLAMINES, CYCLIC AMP AND METABOLIC SUBSTRATES IN MONKEYS SUBJECTED TO CYTOTROPIC ANAPHYLAXIS
Fredholm BB; Revenäs B; Smedegård G; Saldeen T; Strandberg K
Book chapter: HOMEOSTASIS IN INJURY AND SHOCK. 1981;p. 205-206
CATECHOLAMINES, CYCLIC AMP AND METABOLIC SUBSTRATES AFTER ANAPHYLAXIS IN THE RAT
Fredholm BB; Hamberger B; Farnebo L-O
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1981;49:29
EFFECT OF DIFFERENT ALKYLXANTHINES ON ADENOSINE-RECEPTOR MEDIATED INHIBITION OF FAT-CELL CYCLIC-AMP ACCUMULATION
LINDGREN E; FREDHOLM BB
Book chapter: DOPAMINERGIC ERGOT DERIVATIVES AND MOTOR FUNCTION. 1979;p. 141-157
ACTIONS OF ERGOT DERIVATIVES AT DOPAMINE SYNAPSES
FUXE K; SCHWARCZ R; AGNATI L; FREDHOLM B; ÖGREN S-O; KÖHLER C; GUSTAFSSON J-Å
Book chapter: CATECHOLAMINES: BASIC AND CLINICAL FRONTIERS. 1979;p. 256-258
ADENOSINE AS MODULATOR OF ADRENERGIC NEUROEFFECTOR TRANSMISSION
Hedqvist P; Fredholm BB
Book chapter: CATECHOLAMINES: BASIC AND CLINICAL FRONTIERS. 1979;p. 1146-1148
ADENOSINE - A TRANSSYNAPTIC MODULATOR OF NOREPINEPHRINE RELEASE?
Fredholm BB; Hedqvist P
Book chapter: DOPAMINERGIC ERGOT DERIVATIVES AND MOTOR FUNCTION. 1979;p. 73-83
DOPAMINE RECEPTORS AND PHOSPHODIESTERASES
FREDHOLM BB
Conference publication: ACTA PHYSIOLOGICA. 1978;102(1):A81
RELEASE OF ADENOSINE-LIKE MATERIAL FROM ISOLATED PERIFUSED FAT-CELLS
HJEMDAHL P; FREDHOLM BB; SOLLEVI A
Book chapter: ABSTRACTS. 1977;p. 609
1468 INHIBITION BY ACIDOSIS OF CYCLIC AMP ACCUMULATION IN ISOLATED RAT ADIPOCYTES
Hjemdahl P; Fredholm BB
Conference publication: ACTA PHARMACOLOGICA ET TOXICOLOGICA. 1977;41:49
INHIBITION OF ACETYLCHOLINE-RELEASE BY ADENOSINE
GUSTAFSSON L; HEDQVIST P; FREDHOLM BB
Book chapter: ABSTRACTS. 1977;p. 609
1469 ADENOSINE MODULATION OP CYCLIC AMP AND LIPOLYSIS IN ADIPOSE TISSUE
Fredholm BB
Conference publication: ACTA PHYSIOLOGICA. 1975;95(2):A15
VASCULAR AND METABOLIC EFFECTS OF LOCAL COOLING IN CANINE SUBCUTANEOUS ADIPOSE-TISSUE
SOLLEVI A; HJEMDAHL P; FREDHOLM BB
Book chapter: MUSCLE METABOLISM DURING EXERCISE: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1971;p. 249-255
Fat Mobilization and Blood Lactate Concentration
Fredholm BB
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Professor Emeritus/Emerita, Department of Physiology and Pharmacology, Karolinska Institutet, 2025-2025

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Docent, Karolinska Institutet, 1971

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