Annika Karlsson

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: OXFORD OPEN IMMUNOLOGY. 2025;:iqaf011
Capturing the full spectrum of T cell responses with spectral flow cytometry
Olofsson A; Karlsson AC
Article: ADVANCED SCIENCE. 2025;12(16):2416453
Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo
Mikaeloff F; Gelpi M; Escos A; Wang T; Gupta S; Olofsson A; Akusjarvi SS; Schuster S; Naval P; Sood V; Nikouyan N; Knudsen AD; Vestad B; Hogh J; Hov JR; Benfield T; Troseid M; Pawar V; Rucevic M; Benfeitas R; Vegvari A; O'Mahony L; Savai R; Bjorkstrom NK; Lourda M; de Magalhaes JP; Weiss S; Mardinoglu A; Varshney MK; Karlsson AC; Syed YA; Nielsen SD; Neogi U
Article: ISCIENCE. 2025;28(3):112082
Adaptive immune responses against common viruses are sustained and functional in end-of-life patients
Olofsson A; Humbert M; Rekha RS; Frankling MH; Lund-Johansen F; Bergman P; Bjorkhem-Bergman L; Karlsson AC
Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states
Muller TRR; Sekine T; Trubach D; Niessl J; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Olofsson A; Hernandez SPA; Gao Y; Cai C; Soderdahl G; Smith CIE; Osterborg A; Lore K; Sallberg Chen M; Ljungman P; Ljunggren H-G; Karlsson ACC; Saini SK; Aleman S; Buggert M
Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(Supplement_1):75.16
Anamnestic expansion of Omicron-reactive CD8+ T cells after booster SARS-CoV-2 mRNA vaccination across different immunocompromised states
Müller TR; Sekine T; Trubach D; Niessl J; Olofsson A; Gao Y; Cai C; Nowak P; Blennow O; Hansson L; Mielke S; Bergman P; Ljunggren H-G; Karlsson AC; Saini SK; Aleman S; Buggert M
Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(Supplement_1):75.20
Pre-existing SARS-CoV-2-reactive CD4+ T cells are established and highly functional in early childhood
Olofsson A; Humbert M; Niessl J; Hodcroft E; Gao Y; Sohlberg E; Malmberg K-J; Lund-Johansen F; Björkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(12):e2220320120
Functional SARS-CoV-2 cross-reactive CD4⁺ T cells established in early childhood decline with age
Humbert M; Olofsson A; Wullimann D; Niessl J; Hodcroft EB; Cai C; Gao Y; Sohlberg E; Dyrdak R; Mikaeloff F; Neogi U; Albert J; Malmberg K-J; Lund-Johansen F; Aleman S; Bjorkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: CELLS. 2022;11(19):3142
Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection
Johansson E; Kerkman PF; Scharf L; Lindman J; Szojka ZI; Mansson F; Biague A; Medstrand P; Norrgren H; Buggert M; Karlsson AC; Forsell MNE; Esbjornsson J; Jansson M
Article: NATURE MEDICINE. 2022;28(3):472-476
Ancestral SARS-CoV-2-specific T cells cross-recognize the Omicron variant
Gao Y; Cai C; Grifoni A; Muller TR; Niessl J; Olofsson A; Humbert M; Hansson L; Osterborg A; Bergman P; Chen P; Olsson A; Sandberg JK; Weiskopf D; Price DA; Ljunggren H-G; Karlsson AC; Sette A; Aleman S; Buggert M
Journal article: NATURE MEDICINE. 2022
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron
Gao Y; Cai C; Grifoni A; Müller TR; Niessl J; Olofsson A; Humbert M; Hansson L; Österborg A; Bergman P; Chen P; Olsson A; Sandberg JK; Weiskopf D; Price DA; Ljunggren H-G; Karlsson AC; Sette A; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2021;6(64):eabk0894
Identification of resident memory CD8⁺ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue
Niessl J; Sekine T; Lange J; Konya V; Forkel M; Maric J; Rao A; Mazzurana L; Kokkinou E; Weigel W; Llewellyn-Lacey S; Hodcroft EB; Karlsson AC; Fehrm J; Sundman J; Price DA; Mjosberg J; Friberg D; Buggert M
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:744530
Inverted CD8 T-Cell Exhaustion and Co-Stimulation Marker Balance Differentiate Aviremic HIV-2-Infected From Seronegative Individuals
Scharf L; Pedersen CB; Johansson E; Lindman J; Olsen LR; Buggert M; Wilhelmson S; Mansson F; Esbjornsson J; Biague A; Medstrand P; Norrgren H; Karlsson AC; Jansson M
Article: SCIENCE IMMUNOLOGY. 2020;5(53):eabe8063
The known unknowns of T cell immunity to COVID-19
Karlsson AC; Humbert M; Buggert M
Article: JOURNAL OF VIROLOGY. 2020;94(14):e02128-e02119
Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection
Scharf L; Tauriainen J; Buggert M; Hartogensis W; Nolan DJ; Deeks SG; Salemi M; Hecht FM; Karlsson AC
Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):453-465
Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103^-CD8⁺ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium
Gibbs A; Buggert M; Edfeldt G; Ranefall P; Introini A; Cheuk S; Martini E; Eidsmo L; Ball TB; Kimani J; Kaul R; Karlsson AC; Wahlby C; Broliden K; Tjernlund A
Journal article: PLOS PATHOGENS. 2018;14(4):e1006973
Limited immune surveillance in lymphoid tissue by cytolytic CD4+T cells during health and HIV disease (Retracted article. See vol. 21, 2025)
Buggert M; Nguyen S; McLane LM; Steblyanko M; Anikeeva N; Paquin-Proulx D; Del Rio Estrada PM; Ablanedo-Terrazas Y; Noyan K; Reuter MA; Demers K; Sandberg JK; Eller MA; Streeck H; Jansson M; Nowak P; Sonnerborg A; Canaday DH; Naji A; Wherry EJ; Robb ML; Deeks SG; Reyes-Teran G; Sykulev Y; Karlsson AC; Betts MR
Journal article: JOURNAL OF IMMUNOLOGY. 2017;198(Supplement_1):78.25
HIV-induced modifications of TIGIT expression impair CD8 T cell polyfunctionality
Scharf L; Tauriainen J; Frederiksen J; Naji A; Ljunggren H-G; Sönnerborg A; Lund O; Reyes-Terán G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Article: TRANSLATIONAL CANCER RESEARCH. 2017;6:S65-S67
Genetic footprints of T cell exhaustion
Buggert M; Tauriainen J; Karlsson AC
Article: SCIENTIFIC REPORTS. 2017;7:40354
Perturbed CD8⁺ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
Tauriainen J; Scharf L; Frederiksen J; Naji A; Ljunggren H-G; Sonnerborg A; Lund O; Reyes-Teran G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(1):91-106
Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency
Abolhassani H; Edwards ESJ; Ikinciogullari A; Jing H; Borte S; Buggert M; Du L; Matsuda-Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson AC; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Su HC; Pan-Hammarstrom Q
Article: AIDS. 2016;30(16):2415-2426
CD4⁺ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection
Buggert M; Frederiksen J; Lund O; Betts MR; Biague A; Nielsen M; Tauriainen J; Norrgren H; Medstrand P; Karlsson AC; Jansson M
Journal article: PLOS ONE. 2016;11(7):e0160293
Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes (vol 5, e10249, 2010)
Willberg CB; Garrison KE; Jones RB; Meiklejohn DA; Spotts G; Liegler TJ; Ostrowski MA; Karlsson AC; Hecht FM; Nixon DF
Article: AIDS. 2016;30(11):1713-1722
Elevated levels of invariant natural killer T-cell and natural killer cell activation correlate with disease progression in HIV-1 and HIV-2 infections
Bachle SM; Malone DFG; Buggert M; Karlsson AC; Isberg P-E; Biague AJ; Norrgren H; Medstrand P; Moll M; Sandberg JK; Jansson M
Article: CLINICAL INFECTIOUS DISEASES. 2016;62(5):655-663
Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe
Hofstra LM; Sauvageot N; Albert J; Alexiev I; Garcia F; Struck D; Van de Vijver DAMC; Asjo B; Beshkov D; Coughlan S; Descamps D; Griskevicius A; Hamouda O; Horban A; Van Kasteren M; Kolupajeva T; Kostrikis LG; Liitsola K; Linka M; Mor O; Nielsen C; Otelea D; Paraskevis D; Paredes R; Poljak M; Puchhammer-Stoeckl E; Sonnerborg A; Stanekova D; Stanojevic M; Van Laethem K; Zazzi M; Lepej SZ; Boucher CAB; Schmit J-C; Wensing AMJ
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(10):2885-2888
Primary resistance to integrase strand-transfer inhibitors in Europe.
Casadellà M; van Ham PM; Noguera-Julian M; van Kessel A; Pou C; Hofstra LM; Santos JR; Garcia F; Struck D; Alexiev I; Bakken Kran AM; Hoepelman AI; Kostrikis LG; Somogyi S; Liitsola K; Linka M; Nielsen C; Otelea D; Paraskevis D; Poljak M; Puchhammer-Stöckl E; Staneková D; Stanojevic M; Van Laethem K; Zidovec Lepej S; Clotet B; Boucher CAB; Paredes R; Wensing AMJ; SPREAD programme
Article: PLOS ONE. 2015;10(9):e0137635
Multidimensional Clusters of CD4+T Cell Dysfunction Are Primarily Associated with the CD4/CD8 Ratio in Chronic HIV Infection
Frederiksen J; Buggert M; Noyan K; Nowak P; Sonnerborg A; Lund O; Karlsson AC
Article: FRONTIERS IN IMMUNOLOGY. 2015;6:196
Single-cell characterization of in vitro migration and interaction dynamics of T cells expanded with IL-2 and IL-7
Tauriainen J; Gustafsson K; Gothlin M; Gertow J; Buggert M; Frisk TW; Karlsson AC; Uhlin M; Onfelt B
Article: PLOS ONE. 2015;10(4):e0120787
Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences
Eriksson EM; Liegler T; Keh CE; Karlsson AC; Holditch SJ; Pilcher CD; Loeb L; Nixon DF; Hecht FM
Article: BMC INFECTIOUS DISEASES. 2015;15:175
Virologic and immunologic failure, drug resistance and mortality during the first 24 months postpartum among HIV-infected women initiated on antiretroviral therapy for life in the Mitra plus Study, Dar es Salaam, Tanzania
Ngarina M; Kilewo C; Karlsson K; Aboud S; Karlsson A; Marrone G; Leyna G; Ekstroem AM; Biberfeld G
Article: RETROVIROLOGY. 2014;11:105
Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.
Pingen M; Wensing AMJ; Fransen K; De Bel A; de Jong D; Hoepelman AIM; Magiorkinis E; Paraskevis D; Lunar MM; Poljak M; Nijhuis M; Boucher CAB; SPREAD programme
Journal article: PLOS COMPUTATIONAL BIOLOGY. 2014;10(11)
Baseline CD4+ T Cell Counts Correlates inn HIV-1 Synonymous Rate in HLA-B*5701 Subjects with Different Risk of Disease Progression (vol 10, e1003830, 2014)
Karlsson AC
Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2014;85A(11):969-977
NetFCM: A Semi-Automated Web-Based Method for Flow Cytometry Data Analysis
Frederiksen J; Buggert M; Karlsson AC; Lund O
Article: PLOS COMPUTATIONAL BIOLOGY. 2014;10(9):e1003830
Baseline CD4⁺ T Cell Counts Correlates with HIV-1 Synonymous Rate in HLA-B*5701 Subjects with Different Risk of Disease Progression
Norstrom MM; Veras NM; Huang W; Proper MCF; Cook J; Hartogensis W; Hecht FM; Karlsoon AC; Salemi M
Article: BMC INFECTIOUS DISEASES. 2014;14:407
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
Frentz D; Van de Vijver DAMC; Abecasis AB; Albert J; Hamouda O; Jorgensen LB; Kucherer C; Struck D; Schmit J-C; Vercauteren J; Asjo B; Balotta C; Beshkov D; Camacho RJ; Clotet B; Coughlan S; Griskevicius A; Grossman Z; Horban A; Kolupajeva T; Korn K; Kostrikis LG; Liitsola K; Linka M; Nielsen C; Otelea D; Paraskevis D; Paredes R; Poljak M; Puchhammer-Stockl E; Sonnerborg A; Stanekova D; Stanojevic M; Van Wijngaerden E; Wensing AMJ; Boucher CAB
Article: PLOS PATHOGENS. 2014;10(7):e1004251
T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+T Cells in HIV Infection
Buggert M; Tauriainen J; Yamamoto T; Frederiksen J; Ivarsson MA; Michaelsson J; Lund O; Hejdeman B; Jansson M; Sonnerborg A; Koup RA; Betts MR; Karlsson AC
Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4685-4696
Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression
Buggert M; Norstrom MM; Salemi M; Hecht FM; Karlsson AC
Article: PLOS ONE. 2014;9(4):e94495
Patterns of Transmitted HIV Drug Resistance in Europe Vary by Risk Group
Frentz D; van de Vijver D; Abecasis A; Albert J; Hamouda O; Jorgensen L; Kucherer C; Struck D; Schmit J-C; Vercauteren J; Asjo B; Balotta C; Bergin C; Beshkov D; Camacho R; Clotet B; Griskevicius A; Grossman Z; Horban A; Kolupajeva T; Korn K; Kostrikis L; Linka KLM; Nielsen C; Otelea D; Paraskevis D; Paredes R; Poljak M; Puchhammer-Stoeckl E; Sonnerborg A; Stanekova D; Stanojevic M; Vandamme A-M; Boucher C; Wensing A
Article: JOURNAL OF IMMUNOLOGY. 2014;192(5):2099-2108
Multiparametric Bioinformatics Distinguish the CD4/CD8 Ratio as a Suitable Laboratory Predictor of Combined T Cell Pathogenesis in HIV Infection
Buggert M; Frederiksen J; Noyan K; Svard J; Barqasho B; Nnerborg AS; Lund O; Nowak P; Karlsson AC
Article: RETROVIROLOGY. 2013;10:36
Limited cross-border infections in patients newly diagnosed with HIV in Europe
Frentz D; Wensing AMJ; Albert J; Paraskevis D; Abecasis AB; Hamouda O; Jorgensen LB; Kuecherer C; Struck D; Schmit J-C; Asjo B; Balotta C; Beshkov D; Camacho RJ; Clotet B; Coughlan S; De Wit S; Griskevicius A; Grossman Z; Horban A; Kolupajeva T; Korn K; Kostrikis LG; Liitsola K; Linka M; Nielsen C; Otelea D; Paredes R; Poljak M; Puchhammer-Stoeckl E; Sonnerborg A; Stanekova D; Stanojevic M; Vandamme A-M; Boucher CAB; Van de Vijver DAMC
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2013;29(3):602-612
Targeting of Conserved Gag-Epitopes in Early HIV Infection Is Associated with Lower Plasma Viral Load and Slower CD4⁺ T Cell Depletion
Perez CL; Milush JM; Buggert M; Eriksson EM; Larsen MV; Liegler T; Hartogensis W; Bacchetti P; Lund O; Hecht FM; Nixon DF; Karlsson AC
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2012;28(11):1434-1443
Identification of Conserved Subdominant HIV Type 1 CD8⁺ T Cell Epitopes Restricted Within Common HLA Supertypes for Therapeutic HIV Type 1 Vaccines
Karlsson I; Kloverpris H; Jensen KJ; Stryhn A; Buus S; Karlsson A; Vinner L; Goulder P; Fomsgaard A
Article: RETROVIROLOGY. 2012;9:81
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients
Theys K; Deforche K; Vercauteren J; Libin P; van de Vijver DAMC; Albert J; Asjo B; Balotta C; Bruckova M; Camacho RJ; Clotet B; Coughlan S; Grossman Z; Hamouda O; Horban A; Korn K; Kostrikis LG; Kucherer C; Nielsen C; Paraskevis D; Poljak M; Puchhammer-Stockl E; Riva C; Ruiz L; Liitsola K; Schmit J-C; Schuurman R; Sonnerborg A; Stanekova D; Stanojevic M; Struck D; Van Laethem K; Wensing AMJ; Boucher CAB; Vandamme A-M
Article: JOURNAL OF VIROLOGY. 2012;86(18):9802-9816
Combination of Immune and Viral Factors Distinguishes Low-Risk versus High-Risk HIV-1 Disease Progression in HLA-B*5701 Subjects
Norstrom MM; Buggert M; Tauriainen J; Hartogensis W; Prosperi MC; Wallet MA; Hecht FM; Salemi M; Karlsson AC
Article: PLOS ONE. 2012;7(7):e39874
Characterization of HIV-Specific CD4+T Cell Responses against Peptides Selected with Broad Population and Pathogen Coverage
Buggert M; Norstrom MM; Czarnecki C; Tupin E; Luo M; Gyllensten K; Sonnerborg A; Lundegaard C; Lund O; Nielsen M; Karlsson AC
Article: PLOS ONE. 2012;7(3):e33484
Low Prevalence of Transmitted Drug Resistance in Patients Newly Diagnosed with HIV-1 Infection in Sweden 2003-2010
Karlsson A; Bjoerkman P; Bratt G; Ekvall H; Gisslen M; Soennerborg A; Mild M; Albert J
Article: EVOLUTIONARY BIOINFORMATICS. 2012;8:261-269
PhyloTempo: A Set of R Scripts for Assessing and Visualizing Temporal Clustering in Genealogies Inferred from Serially Sampled Viral Sequences
Norstrom MM; Prosperi MCF; Gray RR; Karlsson AC; Salemi M
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2011;27(10):1055-1059
Short Communication: High Prevalence of Drug Resistance in HIV Type 1-Infected Children Born in Honduras and Belize 2001 to 2004
Parham L; Lorenzana de Rivera I; Murillo W; Naver L; Largaespada N; Albert J; Karlsson AC
Article: HUMAN IMMUNOLOGY. 2010;71(7):733-735
Identification of HLA-DPA1*020107 in an individual of Ugandan descent
Czarnecki C; Luo M; Brunham R; Broliden K; Karlsson AC; Plummer FA
Article: JOURNAL OF IMMUNOLOGY. 2010;184(9):5383-5391
Interdisciplinary Analysis of HIV-Specific CD8⁺ T Cell Responses against Variant Epitopes Reveals Restricted TCR Promiscuity
Hoof I; Perez CL; Buggert M; Gustafsson RKL; Nielsen M; Lund O; Karlsson AC
Article: AIDS. 2010;24(7):969-974
Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples
Perez CL; Hasselrot K; Bratt G; Broliden K; Karlsson AC
Article: PLOS ONE. 2010;5(4):e10249
Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+T Cells Recognize Vestigial CTL Epitopes
Willberg CB; Garrison KE; Jones RB; Meiklejohn DJ; Spotts G; Liegler TJ; Ostrowski MA; Karlsson AC; Hecht FM; Nixon DF
Article: HIV MEDICINE. 2010;11(2):95-103
Prevalence of drug resistance and importance of viral load measurements in Honduran HIV-infected patients failing antiretroviral treatment
Murillo W; de Rivera IL; Parham L; Jovel E; Palou E; Karlsson AC; Albert J
Article: AIDS RESEARCH AND THERAPY. 2009;6:15
Reduction of the HIV-1 reservoir in resting CD4+ T-lymphocytes by high dosage intravenous immunoglobulin treatment: a proof-of-concept study.
Lindkvist A; Edén A; Norström MM; Gonzalez VD; Nilsson S; Svennerholm B; Karlsson AC; Sandberg JK; Sönnerborg A; Gisslén M
Article: RETROVIROLOGY. 2009;6:49
Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach
Paraskevis D; Pybus O; Magiorkinis G; Hatzakis A; Wensing AMJ; de Vijver DAV; Albert J; Angarano G; Asjo B; Balotta C; Boeri E; Camacho R; Chaix M-L; Coughlan S; Costagliola D; De Luca A; de Mendoza C; Derdelinckx I; Grossman Z; Hamouda O; Hoepelman IM; Horban A; Korn K; Kuecherer C; Leitner T; Loveday C; MacRae E; Maljkovic-Berry I; Meyer L; Nielsen C; de Coul ELMO; Ormaasen V; Perrin L; Puchhammer-Stoeckl E; Ruiz L; Salminen MO; Schmit J-C; Schuurman R; Soriano V; Stanczak J; Stanojevic M; Struck D; Van Laethem K; Violin M; Yerly S; Zazzi M; Boucher CA; Vandamme A-M
Article: JOURNAL OF IMMUNOLOGY. 2008;180(7):5092-5100
Broadly immunogenic HLA class I supertype-restricted elite CTL epitopes recognized in a diverse population infected with different HIV-1 subtypes
Perez CL; Larsen MV; Gustafsson R; Norstroem MM; Atlas A; Nixon DF; Nielsen M; Lund O; Karlsson AC
Article: JOURNAL OF VIROLOGY. 2007;81(20):11543-11548
Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from gag to pol
Karlsson AC; Chapman JM; Heiken BD; Hoh R; Kallas EG; Martin JN; Hecht FM; Deeks SG; Nixon DF
Article: PLOS ONE. 2007;2(2):e225
Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape
Karlsson AC; Iversen AKN; Chapman JM; de Oliveira T; Spotts G; McMichael AJ; Davenport MP; Hecht FM; Nixon DF
Article: VIROLOGY. 2006;347(1):117-126
CD8 T cell effector maturation in HIV-1-infected children
Jordan KA; Furlan SN; Gonzalez VD; Karlsson AC; Quigley MF; Deeks SG; Rosenberg MG; Nixon DF; Sandberg JK
Article: CLINICAL INFECTIOUS DISEASES. 2006;42(5):700-708
Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection
Hare CB; Pappalardo BL; Busch MP; Karlsson AC; Phelps BH; Alexander SS; Bentsen C; Ramstead CA; Nixon DF; Levy JA; Hecht FM
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2004;288(1-2):135-147
ELISPOT cell rescue
Meiklejohn DA; Karlsson RK; Karlsson AC; Chapman JM; Nixon DF; Schweighardt B
Article: AIDS. 2004;18(7):981-989
Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia
Karlsson AC; Younger SR; Martin JN; Grossman Z; Sinclair E; Hunt PW; Hagos E; Nixon DF; Deeks SG
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2003;283(1-2):141-153
Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells
Karlsson AC; Martin JN; Younger SR; Bredt BM; Epling L; Ronquillo R; Varma A; Deeks SG; McCune JM; Nixon DF; Sinclair E
Article: JOURNAL OF VIROLOGY. 2003;77(12):6743-6752
Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene
Karlsson AC; Deeks SG; Barbour JD; Heiken BD; Younger SR; Hoh R; Lane M; Sällberg M; Ortiz GM; Demarest JF; Liegler T; Grant RM; Martin JN; Nixon DF
Article: HIV MEDICINE. 2002;3(1):1-11
The selection and evolution of viral quasispecies in HIV-1 infected children.
Nowak P; Karlsson AC; Naver L; Bohlin AB; Piasek A; Sönnerborg A
Article: JOURNAL OF INFECTIOUS DISEASES. 2001;184(11):1392-1401
Recent origin of human immunodeficiency virus type 1 variants in resting CD4⁺ T lymphocytes in untreated and suboptimally treated subjects
Karlsson AC; Lindkvist A; Lindbäck S; Gaines H; Sönnerborg A
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2001;17(5):409-416
Initiation of therapy during primary HIV type 1 infection results in a continuous decay of proviral DNA and a highly restricted viral evolution
Karlsson AC; Birk M; Lindbäck S; Gaines H; Mittler JE; Sönnerborg A
Article: AIDS. 2000;14(15):2333-2339
Diagnosis of primary HIV-1 infection and duration of follow-up after HIV exposure
Lindbäck S; Thorstensson R; Karlsson AC; von Sydow M; Flamholc L; Blaxhult A; Sönnerborg A; Biberfeld G; Gaines H
Article: AIDS. 2000;14(15):2283-2291
Viral dynamics in primary HIV-1 infection
Lindbäck S; Karlsson AC; Mittler J; Blaxhult A; Carlsson M; Briheim G; Sönnerborg A; Gaines H
Article: JOURNAL OF VIROLOGY. 1999;73(7):6191-6196
Reappearance of founder virus sequence in human immunodeficiency virus type 1-infected patients
Karlsson AC; Gaines H; Sällberg M; Lindbäck S; Sönnerborg A
Article: AIDS. 1998;12(8):839-847
Characterization of the viral population during primary HIV-1 infection
Karlsson AC; Lindbäck S; Gaines H; Sönnerborg A
Visa fler

Alla övriga publikationer

Corrigendum: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2025;122(5):e2426095122
Functional SARS- CoV- 2 cross- reactive CD4⁺ T cells established in early childhood decline with age (vol 120, e2220320120, 2023)
Humbert M; Olofsson A; Wullimann D; Niessl J; Hodcroft EB; Cai C; Gao Y; Sohlberg E; Dyrdak R; Mikaeloff F; Neogi U; Albert J; Malmberg K-J; Lund-Johansen F; Aleman S; Bjoerkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:19
Pregnancy management of women living with human immunodeficiency virus 2010-2019 in Stockholm, Sweden
Pettersson K; Jones E; Pettersson K; Naver L; Karlsson A
Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
Anamnestic expansion of Omicron-reactive CD8+T cells after booster SARS-CoV-2 mRNA vaccination across different immunocompromised states
Mueller TR; Sekine T; Trubach D; Niessl J; Olofsson A; Gao Y; Cai C; Nowak P; Blennow O; Hansson L; Mielke S; Bergman P; Ljunggren H-G; Karlsson AC; Saini SK; Aleman S; Buggert M
Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
Pre-existing SARS-CoV-2-reactive CD4⁺ T cells are established and highly functional in early childhood
Olofsson A; Humbert M; Niessl J; Hodcroft E; Gao Y; Sohlberg E; Malmberg K-J; Lund-Johansen F; Bjorkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Preprint: RESEARCH SQUARE. 2022
Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron (B.1.1.529)
Gao Y; Cai C; Grifoni A; Müller T; Niessl J; Olofsson A; Humbert M; Hansson L; Österborg A; Bergman P; Chen P; Olsson A; Sandberg J; Weiskopf D; Price D; Ljunggren H-G; Karlsson A; Sette A; Aleman S; Buggert M
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):288-289
Increased numbers of CD103^-CD8⁺ T_RM cells in the cervical mucosa of HIV-infected women
Gibbs A; Buggert M; Edfeldt G; Ranefall P; Introini A; Cheuk S; Martini E; Eidsmo L; Hirbod T; Ball TB; Kimani J; Kaul R; Karlsson AC; Wahlby C; Broliden K; Tjernlund A
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):318
Modifications of TIGIT expression contribute to CD8 T cell exhaustion in chronic virus infection
Tauriainen J; Scharf L; Frederiksen J; Naji A; Ljunggren H-G; Sonnerborg A; Lund O; Reyes-Teran G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Conference publication: JOURNAL OF IMMUNOLOGY. 2017;198(1)
HIV-induced modifications of TIGIT expression impair CD8 T cell polyfunctionality
Scharf L; Tauriainen J; Frederiksen J; Naji A; Ljunggren H-G; Sonnerborg A; Lund O; Reyes-Teran G; Hecht FM; Deeks SG; Betts MR; Buggert M; Karlsson AC
Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2017;37(2):230
COMBINED IMMUNODEFICIENCY AND EPSTEIN-BARR VIRUS-INDUCED B CELL MALIGNANCY IN HUMANS WITH INHERITED CD70 DEFICIENCY
Jing H; Abolhassani H; Edwards ESJ; Ikinciogullari KA; Borte S; Buggert M; Du L; Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson A; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Pan-Hammarstrom Q; Su HC
Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2016;32:307
Analysis of the Distribution of CD103 on CD8 T Cells in Blood and Genital Mucosa of HIV-infected Female Sex Workers
Gibbs A; Buggert M; Ranefall P; Introini A; Cheuk S; Eidsmo L; Hirbod T; Ball TB; Kimani J; Kaul R; Karlsson AC; Wahlby C; Broliden K; Tjernlund A
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;77(4):325
NetFCM: A Tool for Automated Flow Cytometric Data Analysis
Frederiksen J; Lund O; Buggert M; Karlsson A
Review: NEW MICROBIOLOGICA. 2012;35(2):101-111
Towards a new paradigm linking virus molecular evolution and pathogenesis: experimental design and phylodynamic inference
Norstrom MM; Karlsson AC; Salemi M
Conference publication: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2011;27(10):A88
Interdisciplinary Evaluation of Broadly-Reactive HLA Class II Restricted Epitopes Eliciting HIV-Specific CD4+T Cell Responses
Buggert M; Norstrom M; Lundegaard C; Lund O; Nielsen M; Karlsson AC
Conference publication: ANTIVIRAL THERAPY. 2011;16:A139
Drug resistance in an MTCT programme in Honduras
Parham L; Lorenzana IJ; Albert J; Karlsson A
Conference publication: 2010;:658-659
PopCover
Lundegaard C; Buggert M; Karlsson A; Lund O; Perez C; Nielsen M
Meeting abstract: RETROVIROLOGY. 2009;6:p231
Induction of systemic HIV-1 specific cellular immune responses by oral exposure in exposed uninfected partner of discordant couples
Perez C; Hasselrot K; Broliden K; Karlsson A
Letter: LANCET. 2005;365(9475):1924-1925
Multidrug-resistant, dual-tropic HIV-1 and rapid progression
Nixon DF; Deeks SG; Shacklett BL; Karlsson AC
Doctoral thesis: 2000
Viral dynamics and evolution following primary HIV-1 infection
Karlsson AC

Forskningsbidrag

Clinical and translational studies on cancer related fatigue in palliative care. Focus on vitamin D and the immune system.
Swedish Research Council
1 January 2023 - 31 December 2025
Cellular and molecular dynamics of antigen-specific T cells in HIV-treated children, pregnant women, and human cancer affecting immune function, development and health
Swedish Research Council
1 January 2021 - 31 December 2023
Molecular dynamics of T cell exhaustion in human viral infection and cancer affecting immune recovery and health
Swedish Research Council
1 January 2018 - 31 December 2020
A translational approach to link clinical, virological and immunological findings toward a functional cure for HIV
Swedish Research Council
1 January 2013 - 31 December 2017
The impact, role, and consequences of HIV-1 immune escape mutations on viral fitness, immune function, and clinical outcome
Swedish Research Council
1 January 2010 - 31 December 2012

Anställningar

Lektor, Laboratoriemedicin, Karolinska Institutet, 2024-
Lektor, Medicin, Huddinge, Karolinska Institutet, 2025-2026

Examina och utbildning

Docent, Virologi, Karolinska Institutet, 2009
MEDICINE DOKTORSEXAMEN, Institutionen för laboratoriemedicin, Karolinska Institutet, 2000
LICENTIATEXAMEN, Institutionen för laboratoriemedicin, Karolinska Institutet, 1998

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI