Ann-Charlotte Granholm-Bentley

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: THE FASEB JOURNAL. 2019;33(4):5082-5088
Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury.
Goetzl EJ; Elahi FM; Mustapic M; Kapogiannis D; Pryhoda M; Gilmore A; Gorgens KA; Davidson B; Granholm A-C; Ledreux A
Article: ALZHEIMER'S AND DEMENTIA. 2017;13(5):541-549
Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome
Hamlett ED; Goetzl EJ; Ledreux A; Vasilevko V; Boger HA; LaRosa A; Clark D; Carroll SL; Carmona-Iragui M; Fortea J; Mufson EJ; Sabbagh M; Mohammed AH; Hartley D; Doran E; Lott IT; Granholm A-C
Article: PLOS ONE. 2017;12(12):e0189821
A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats.
Bharani KL; Derex R; Granholm A-C; Ledreux A
Article: FRONTIERS IN AGING NEUROSCIENCE. 2017;9:284
Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice.
Buhusi M; Etheredge C; Granholm A-C; Buhusi CV
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2016;55(2):645-657
BDNF Responses in Healthy Older Persons to 35 Minutes of Physical Exercise, Cognitive Training, and Mindfulness: Associations with Working Memory Function
Hakansson K; Ledreux A; Daffner K; Terjestam Y; Bergman P; Carlsson R; Kivipelto M; Winblad B; Granholm A-C; Mohammed AKH
Article: BEHAVIOURAL BRAIN RESEARCH. 2016;312:294-304
Detrimental effects of a high fat/high cholesterol diet on memory and hippocampal markers in aged rats
Ledreux A; Wang X; Schultzberg M; Granholm A-C; Freeman LR
Article: NEUROSCIENCE LETTERS. 2016;621:68-74
Memory and hippocampal architecture following short-term midazolam in western diet-treated rats.
Rosenberger DS; Falangola MF; Ledreux A; Nie X; Suhre WM; Boger HA; Granholm A-C
Article: MOLECULAR NEUROBIOLOGY. 2016;53(4):2733-2749
Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ₄₂ Phagocytosis
Zhu M; Wang X; Hjorth E; Colas RA; Schroeder L; Granholm A-C; Serhan CN; Schultzberg M
Article: BRAIN RESEARCH. 2016;1631:34-45
BDNF levels are increased by aminoindan and rasagiline in a double lesion model of Parkinson׳s disease.
Ledreux A; Boger HA; Hinson VK; Cantwell K; Granholm A-C
Article: CURRENT ALZHEIMER RESEARCH. 2015;13(1):35-52
Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.
Hamlett ED; Boger HA; Ledreux A; Kelley CM; Mufson EJ; Falangola MF; Guilfoyle DN; Nixon RA; Patterson D; Duval N; Granholm A-CE
Article: NEUROIMAGE. 2015;113:235-245
Histologic validation of locus coeruleus MRI contrast in post-mortem tissue.
Keren NI; Taheri S; Vazey EM; Morgan PS; Granholm A-CE; Aston-Jones GS; Eckert MA
Article: ALZHEIMER'S AND DEMENTIA. 2015;11(6):700-709
Down syndrome and Alzheimer's disease: Common pathways, common goals.
Hartley D; Blumenthal T; Carrillo M; DiPaolo G; Esralew L; Gardiner K; Granholm A-C; Iqbal K; Krams M; Lemere C; Lott I; Mobley W; Ness S; Nixon R; Potter H; Reeves R; Sabbagh M; Silverman W; Tycko B; Whitten M; Wisniewski T
Article: MAGNETIC RESONANCE IMAGING. 2015;33(4):437-447
Evidence of altered age-related brain cytoarchitecture in mouse models of down syndrome: a diffusional kurtosis imaging study.
Nie X; Hamlett ED; Granholm A-C; Hui ES; Helpern JA; Jensen JH; Boger HA; Collins HR; Falangola MF
Article: JOURNAL OF NEUROSCIENCE. 2015;35(4):1343-1353
Designer receptors enhance memory in a mouse model of Down syndrome.
Fortress AM; Hamlett ED; Vazey EM; Aston-Jones G; Cass WA; Boger HA; Granholm A-CE
Article: INT NEUROPSYCHIATR DIS J. 2015;3(1):19-26
Pilot Study and Review: Physiological Differences in BDNF, a Potential Biomarker in Males and Females with Autistic Disorder.
Spratt EG; Granholm A-C; Carpenter LA; Boger HA; Papa CE; Logan S; Chaudhary H; Boatwright S-W; Brady KT
Article: ALZHEIMER'S AND DEMENTIA. 2015;11(1):70-98
At the interface of sensory and motor dysfunctions and Alzheimer's disease.
Albers MW; Gilmore GC; Kaye J; Murphy C; Wingfield A; Bennett DA; Boxer AL; Buchman AS; Cruickshanks KJ; Devanand DP; Duffy CJ; Gall CM; Gates GA; Granholm A-C; Hensch T; Holtzer R; Hyman BT; Lin FR; McKee AC; Morris JC; Petersen RC; Silbert LC; Struble RG; Trojanowski JQ; Verghese J; Wilson DA; Xu S; Zhang LI
Article: ALZHEIMER'S AND DEMENTIA. 2015;11(1):40-50.e1-2-50
Resolution of inflammation is altered in Alzheimer's disease
Wang X; Zhu M; Hjorth E; Cortes-Toro V; Eyjolfsdottir H; Graff C; Nennesmo I; Palmblad J; Eriksdotter M; Sambamurti K; Fitzgerald JM; Serhan CN; Granholm A-C; Schultzberg M
Article: JOURNAL OF NEUROINFLAMMATION. 2014;11:171
Estrogen receptor alpha deficiency protects against development of cognitive impairment in murine lupus.
Cunningham MA; Wirth JR; Freeman LR; Boger HA; Granholm A-C; Gilkeson GS
Article: ATHEROSCLEROSIS. 2014;237(2):460-463
Intracranial atherosclerosis: correlation between in-vivo 3T high resolution MRI and pathology.
Turan TN; Rumboldt Z; Granholm A-C; Columbo L; Welsh CT; Lopes-Virella MF; Spampinato MV; Brown TR
Article: JOURNAL OF NEUROSCIENCE METHODS. 2014;231:31-37
Three-dimensional rodent motion analysis and neurodegenerative disorders.
Karakostas T; Hsiang S; Boger H; Middaugh L; Granholm A-C
Article: BRAIN. 2014;137(Pt 3):860-872
Nerve growth factor metabolic dysfunction in Down's syndrome brains.
Iulita MF; Do Carmo S; Ower AK; Fortress AM; Flores Aguilar L; Hanna M; Wisniewski T; Granholm A-C; Buhusi M; Busciglio J; Cuello AC
Article: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 2013;104:10-19
Glial cell-line derived neurotrophic factor (GDNF) replacement attenuates motor impairments and nigrostriatal dopamine deficits in 12-month-old mice with a partial deletion of GDNF.
Littrell OM; Granholm A-C; Gerhardt GA; Boger HA
Article: BRAIN. 2012;135(Pt 9):2736-2749
PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice
Zhang Y; Granholm A-C; Huh K; Shan L; Diaz-Ruiz O; Malik N; Olson L; Hoffer BJ; Lupica CR; Hoffman AF; Baeckman CM
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2012;32(4):643-653
Vascular changes in rat hippocampus following a high saturated fat and cholesterol diet.
Freeman LR; Granholm A-CE
Article: NEUROBIOLOGY OF AGING. 2012;33(2):427.e1-427.14
Enhanced dopamine transporter activity in middle-aged Gdnf heterozygous mice.
Littrell OM; Pomerleau F; Huettl P; Surgener S; McGinty JF; Middaugh LD; Granholm A-C; Gerhardt GA; Boger HA
Article: CURRENT GERONTOLOGY AND GERIATRICS RESEARCH. 2012;2012:463909-13
Age-related neurodegeneration and memory loss in down syndrome.
Lockrow JP; Fortress AM; Granholm A-CE
Article: BEHAVIOURAL BRAIN RESEARCH. 2011;221(2):610-622
Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome.
Lockrow J; Boger H; Bimonte-Nelson H; Granholm A-C
Article: BRAIN PATHOLOGY. 2011;21(3):330-348
Prenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous mice.
Granholm A-C; Zaman V; Godbee J; Smith M; Ramadan R; Umphlet C; Randall P; Bhat NR; Rohrer B; Middaugh LD; Boger HA
Article: GENES, BRAIN AND BEHAVIOR. 2011;10(2):186-198
Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging.
Boger HA; Mannangatti P; Samuvel DJ; Saylor AJ; Bender TS; McGinty JF; Fortress AM; Zaman V; Huang P; Middaugh LD; Randall PK; Jayanthi LD; Rohrer B; Helke KL; Granholm A-C; Ramamoorthy S
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2011;23(3):471-489
A noradrenergic lesion exacerbates neurodegeneration in a Down syndrome mouse model.
Lockrow J; Boger H; Gerhardt G; Aston-Jones G; Bachman D; Granholm A-C
Article: THE JOURNAL OF THE SOUTH CAROLINA MEDICAL ASSOCIATION. 2011;107(1):8-12
Use of seniors as mentors to medical students: a collaboration between the University of South Carolina School of Medicine and the Medical University of South Carolina.
Wiley MK; Granholm A-C; Bachman D; Wieland D; Roberts E; Hardin R; Dever-Bumba M; Eleazer GP
Article: JOURNAL OF AGING RESEARCH. 2011;2011:460543-10
Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats.
Fortress AM; Buhusi M; Helke KL; Granholm A-CE
Article: NUTRITIONAL NEUROSCIENCE. 2011;14(1):32-44
Diet-induced effects on neuronal and glial elements in the middle-aged rat hippocampus.
Freeman LR; Haley-Zitlin V; Stevens C; Granholm A-C
Article: CELL TRANSPLANTATION. 2011;20(10):1499-1514
A high-fat/high-cholesterol diet inhibits growth of fetal hippocampal transplants via increased inflammation.
Freeman LR; Small BJ; Bickford PC; Umphlet C; Granholm A-C
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2010;45(3):226-233
Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin.
Fukuda Y; Berry TL; Nelson M; Hunter CL; Fukuhara K; Imai H; Ito S; Granholm-Bentley A-C; Kaplan AP; Mutoh T
Article: GLIA. 2010;58(6):679-690
Blueberry supplementation attenuates microglial activation in hippocampal intraocular grafts to aged hosts.
Willis LM; Freeman L; Bickford PC; Quintero EM; Umphlet CD; Moore AB; Goetzl L; Granholm A-C
Article: EXPERIMENTAL NEUROLOGY. 2009;216(2):278-289
Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model.
Lockrow J; Prakasam A; Huang P; Bimonte-Nelson H; Sambamurti K; Granholm A-C
Article: NEUROBIOLOGY OF DISEASE. 2009;33(3):459-466
Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice.
Boger HA; Middaugh LD; Granholm A-C; McGinty JF
Article: BRAIN RESEARCH. 2008;1241:18-28
Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene.
Boger HA; Middaugh LD; Zaman V; Hoffer B; Granholm A-C
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2008;28(8):1557-1568
The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior.
Zaman V; Boger HA; Granholm A-C; Rohrer B; Moore A; Buhusi M; Gerhardt GA; Hoffer BJ; Middaugh LD
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2008;14(2):133-145
Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat.
Granholm A-C; Bimonte-Nelson HA; Moore AB; Nelson ME; Freeman LR; Sambamurti K
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2008;28(6):1150-1164
Dietary blueberry supplementation affects growth but not vascularization of neural transplants.
Willis LM; Small BJ; Bickford PC; Umphlet CD; Moore AB; Granholm A-CE
Article: EXPERIMENTAL AGING RESEARCH. 2007;34(1):13-26
Patterns of neurotrophin protein levels in male and female Fischer 344 rats from adulthood to senescence: how young is "young" and how old is "old"?
Bimonte-Nelson HA; Granholm A-CE; Nelson ME; Moore AB
Article: JOURNAL OF NEUROSCIENCE. 2007;27(33):8816-8825
Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice.
Boger HA; Middaugh LD; Patrick KS; Ramamoorthy S; Denehy ED; Zhu H; Pacchioni AM; Granholm A-C; McGinty JF
Article: BRAIN RESEARCH. 2007;1141:56-64
Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat.
Paredes D; Granholm A-C; Bickford PC
Article: BRAIN RESEARCH. 2007;1133(1):10-19
Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures.
af Bjerkén S; Boger HA; Nelson M; Hoffer BJ; Granholm A-C; Strömberg I
Article: NEUROSCIENCE LETTERS. 2007;413(2):110-114
Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation.
Williams B; Granholm A-C; Sambamurti K
Article: EXPERIMENTAL NEUROLOGY. 2006;202(2):336-347
A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra.
Boger HA; Middaugh LD; Huang P; Zaman V; Smith AC; Hoffer BJ; Tomac AC; Granholm A-C
Article: PSYCHOPHARMACOLOGY. 2006;188(4):605-618
ERK-mediated NGF signaling in the rat septo-hippocampal pathway diminishes with age.
Williams BJ; Bimonte-Nelson HA; Granholm-Bentley A-C
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;24(1):229-242
Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female rats.
Bimonte-Nelson HA; Francis KR; Umphlet CD; Granholm A-C
Article: BRAIN RESEARCH. 2006;1093(1):198-207
Behavioral and morphological effects of minocycline in the 6-hydroxydopamine rat model of Parkinson's disease.
Quintero EM; Willis L; Singleton R; Harris N; Huang P; Bhat N; Granholm A-C
Article: BEHAVIOURAL BRAIN RESEARCH. 2006;169(2):256-262
Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats.
French KL; Granholm A-CE; Moore AB; Nelson ME; Bimonte-Nelson HA
Article: BRAIN RESEARCH. 2006;1068(1):257-260
Partial deletion of glial cell line-derived neurotrophic factor (GDNF) in mice: Effects on sucrose reward and striatal GDNF concentrations.
Griffin WC; Boger HA; Granholm A-C; Middaugh LD
Article: EXPERIMENTAL NEUROLOGY. 2005;196(1):30-40
Altered NGF response but not release in the aged septo-hippocampal cholinergic system.
Williams B; Nelson M; Granholm A-C; Coultrap S; Browning M; Curtis M
Article: CELL TRANSPLANTATION. 2005;14(1):21-29
Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants.
Willis L; Quintero EM; Nelson M; Granholm A-C
Article: NEUROREPORT. 2004;15(17):2659-2663
Progesterone counteracts estrogen-induced increases in neurotrophins in the aged female rat brain.
Bimonte-Nelson HA; Nelson ME; Granholm A-CE
Article: ANNALS OF NEUROLOGY. 2004;56(5):675-688
Minocycline prevents cholinergic loss in a mouse model of Down's syndrome.
Hunter CL; Bachman D; Granholm A-C
Article: BEHAVIORAL NEUROSCIENCE. 2004;118(4):707-714
Ovarian hormones and cognition in the aged female rat: II. progesterone supplementation reverses the cognitive enhancing effects of ovariectomy.
Bimonte-Nelson HA; Singleton RS; Williams BJ; Granholm A-CE
Article: NEUROBIOLOGY OF AGING. 2004;25(7):873-884
Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen.
Hunter CL; Bimonte-Nelson HA; Nelson M; Eckman CB; Granholm A-C
Article: NEUROSCIENCE. 2004;124(1):137-146
Glial cell line-derived neurotrophic factor is essential for neuronal survival in the locus coeruleus-hippocampal noradrenergic pathway.
Quintero EM; Willis LM; Zaman V; Lee J; Boger HA; Tomac A; Hoffer BJ; Strömberg I; Granholm A-C
Article: BEHAVIORAL NEUROSCIENCE. 2003;117(6):1395-1406
Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance.
Bimonte-Nelson HA; Singleton RS; Hunter CL; Price KL; Moore AB; Granholm A-CE
Article: PHYSIOLOGY AND BEHAVIOR. 2003;80(1):27-36
Age-related sex differences in spatial learning and basal forebrain cholinergic neurons in F344 rats.
Veng LM; Granholm A-C; Rose GM
Article: EXPERIMENTAL NEUROLOGY. 2003;181(2):301-312
Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats.
Bimonte-Nelson HA; Singleton RS; Nelson ME; Eckman CB; Barber J; Scott TY; Granholm A-CE
Article: NEUROSCIENCE RESEARCH. 2003;45(4):437-445
Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.
Hunter CL; Isacson O; Nelson M; Bimonte-Nelson H; Seo H; Lin L; Ford K; Kindy MS; Granholm A-C
Article: BRAIN RESEARCH. 2003;967(1-2):306-310
Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat.
Albeck D; Mesches MH; Juthberg S; Browning M; Bickford PC; Rose GM; Granholm A-C
Article: BEHAVIOURAL BRAIN RESEARCH. 2003;139(1-2):47-57
Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome.
Bimonte-Nelson HA; Hunter CL; Nelson ME; Granholm A-CE
Article: BEHAVIOURAL BRAIN RESEARCH. 2003;138(2):121-131
Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory.
Hunter CL; Bimonte HA; Granholm ACE
Article: NEUROBIOLOGY OF AGING. 2003;24(1):37-48
Age-related deficits as working memory load increases: relationships with growth factors.
Bimonte HA; Nelson ME; Granholm A-CE
Article: HIPPOCAMPUS. 2003;13(8):905-914
Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.
Granholm A-C; Sanders L; Seo H; Lin L; Ford K; Isacson O
Article: PHYSIOLOGY AND BEHAVIOR. 2002;77(2-3):371-385
Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome.
Granholm A-CE; Ford KA; Hyde LA; Bimonte HA; Hunter CL; Nelson M; Albeck D; Sanders LA; Mufson EJ; Crnic LS
Article: NEUROSCIENCE LETTERS. 2002;328(1):50-54
Spatial memory testing decreases hippocampal amyloid precursor protein in young, but not aged, female rats.
Bimonte HA; Granholm A-CE; Seo H; Isacson O
Article: PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 2002;73(1):167-175
Environmental influences on brain neurotrophins in rats
Pham TM; Winblad B; Granholm AC; Mohammed AH
Article: MICROSCOPY RESEARCH AND TECHNIQUE. 2001;54(5):309-316
GDNF improves cerebellar Purkinje neuron function in aged F344 rats.
Bickford PC; Bowenkamp K; Taglialatela G; Hoertig G; Granholm AC
Article: MICROSCOPY RESEARCH AND TECHNIQUE. 2001;54(5):298-308
Effects of age and GDNF on noradrenergic innervation of the hippocampal formation: studies from intraocular grafts.
Granholm AC; Helt C; Srivastava N; Backman C; Gerhardt GA
Article: EXPERIMENTAL NEUROLOGY. 2001;170(2):258-269
Neuroprotection of grafted neurons with a GDNF/caspase inhibitor cocktail.
Helt CE; Hoernig GR; Albeck DS; Gerhardt GA; Ickes B; Reyland ME; Quissell DO; Strömberg I; Granholm AC
Article: BRAIN RESEARCH. 2001;890(1):86-99
Intranigral transplantation of solid tissue ventral mesencephalon or striatal grafts induces behavioral recovery in 6-OHDA-lesioned rats.
Palmer MR; Granholm AC; van Horne CG; Giardina KE; Freund RK; Moorhead JW; Gerhardt GA
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2000;427(3):440-454
Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion.
Zuch CL; Nordstroem VK; Briedrick LA; Hoernig GR; Granholm AC; Bickford PC
Article: JOURNAL OF NEUROSCIENCE. 2000;20(9):3182-3190
Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons.
Granholm AC; Reyland M; Albeck D; Sanders L; Gerhardt G; Hoernig G; Shen L; Westphal H; Hoffer B
Article: EXPERIMENTAL NEUROLOGY. 2000;161(2):647-663
Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome.
Granholm AC; Sanders LA; Crnic LS
Article: CELL AND TISSUE RESEARCH. 1999;297(1):67-79
Anatomical distribution of glycoprotein 93 (gp93) on nerve fibers during rat brain development.
Henry S; Pfenninger KH; Mott JL; Granholm AC
Article: NEUROSCIENCE. 1999;94(1):279-286
Changes in brain nerve growth factor levels and nerve growth factor receptors in rats exposed to environmental enrichment for one year
Pham TM; Ickes B; Albeck D; Söderström S; Granholm AC; Mohammed AH
Article: NEUROSCIENCE. 1998;86(1):241-255
The hyaluronan receptor RHAMM in noradrenergic fibers contributes to axon growth capacity of locus coeruleus neurons in an intraocular transplant model.
Nagy JI; Price ML; Staines WA; Lynn BD; Granholm AC
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 1997;387(1):1-11
Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors.
Bäckman C; Rose GM; Bartus RT; Hoffer BJ; Mufson EJ; Granholm AC
Article: EXPERIMENTAL BRAIN RESEARCH. 1997;116(1):29-38
Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum.
Granholm AC; Mott JL; Bowenkamp K; Eken S; Henry S; Hoffer BJ; Lapchak PA; Palmer MR; van Horne C; Gerhardt GA
Article: NEUROREPORT. 1997;8(9-10):2293-2298
A non-invasive transport system for GDNF across the blood-brain barrier.
Albeck DS; Hoffer BJ; Quissell D; Sanders LA; Zerbe G; Granholm AC
Article: EXPERIMENTAL NEUROLOGY. 1997;145(2 Pt 1):524-535
Collateral sprouting of central noradrenergic neurons during aging: histochemical and neurochemical studies in intraocular triple transplants.
Srivastava N; Granholm AC; Gerhardt GA
Article: JOURNAL OF NEUROSCIENCE. 1997;17(3):1168-1178
Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies.
Granholm AC; Srivastava N; Mott JL; Henry S; Henry M; Westphal H; Pichel JG; Shen L; Hoffer BJ
Article: EXPERIMENTAL NEUROLOGY. 1996;141(2):181-189
Effects of GDNF on fetal septal forebrain transplants in oculo.
Price ML; Hoffer BJ; Granholm AC
Article: EXPERIMENTAL BRAIN RESEARCH. 1996;111(1):1-7
6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor.
Bowenkamp KE; David D; Lapchak PL; Henry MA; Granholm AC; Hoffer BJ; Mahalik TJ
Article: JOURNAL OF NEUROSCIENCE. 1996;16(17):5437-5442
Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy.
Bäckman C; Rose GM; Hoffer BJ; Henry MA; Bartus RT; Friden P; Granholm AC
Article: NATURE. 1996;382(6586):73-76
Defects in enteric innervation and kidney development in mice lacking GDNF.
Pichel JG; Shen L; Sheng HZ; Granholm AC; Drago J; Grinberg A; Lee EJ; Huang SP; Saarma M; Hoffer BJ; Sariola H; Westphal H
Article: EXPERIMENTAL NEUROLOGY. 1995;136(1):12-21
Characterization of histaminergic H3 receptors in intraocular tuberomammillary transplants containing histaminergic neurons.
Bergman H; Prell GD; Lupica CR; Granholm AC
Article: CELL AND TISSUE RESEARCH. 1995;282(1):49-57
Tyrosine hydroxylase in the cerebral ganglia of the American cockroach (Periplaneta americana L.): an immunohistochemical study.
Granholm AC; Price ML; Owen MD
Article: JOURNAL OF COMPARATIVE NEUROLOGY. 1995;355(4):479-489
Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons.
Bowenkamp KE; Hoffman AF; Gerhardt GA; Henry MA; Biddle PT; Hoffer BJ; Granholm AC
Article: EXPERIMENTAL NEUROLOGY. 1995;132(1):1-15
EFFECTS OF TRANSFERRIN RECEPTOR ANTIBODY-NGF CONJUGATE ON YOUNG AND AGED SEPTAL TRANSPLANTS IN OCULO
BACKMAN C; BIDDLE PT; EBENDAL T; FRIDEN PM; GERHARDT GA; HENRY MA; MACKERLOVA L; SODERSTROM S; STROMBERG I; WALUS L; HOFFER BJ; GRANHOLM AC
Article: BRAIN RESEARCH BULLETIN. 1995;36(5):425-432
Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo.
Hudson J; Granholm AC; Gerhardt GA; Henry MA; Hoffman A; Biddle P; Leela NS; Mackerlova L; Lile JD; Collins F
Article: NEUROSCIENCE. 1995;64(1):61-70
Intracranial transplantation and survival of tuberomammillary histaminergic neurons.
Bergman H; Nagy JI; Granholm AC
Article: HIPPOCAMPUS. 1995;5(6):584-594
Hypothalamic tissue stimulates hippocampal pyramidal neuron survival during development: evidence from intraocular double transplants.
Curtis M; Bergman H; Price ML; Srivastava N; Granholm AC
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Alla övriga publikationer

Review: FREE RADICAL BIOLOGY AND MEDICINE. 2018;114:110-121
Exosomal biomarkers in Down syndrome and Alzheimer's disease.
Hamlett ED; Ledreux A; Potter H; Chial HJ; Patterson D; Espinosa JM; Bettcher BM; Granholm A-C
Meeting abstract: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2017;49(5):836
Assessments Of Standing Balance In Division I Athletes With History Of Concussion: A Pilot Study
Powell JJ; Pryhoda MK; Belgasem H; Sanders W; Shelburne KB; Granholm-Bentley A-C; Davidson BS
Meeting abstract: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2017;49(5):835
Concussion History And Kinematics Of Dynamic Balance In Division I Athletes: A Pilot Study
Pryhoda MK; Powell J; Belgasem H; Landusky C; Shelburne KB; Granholm-Bentley A-C; Davidson BS
Review: NUTRITIONAL NEUROSCIENCE. 2014;17(6):241-251
Damaging effects of a high-fat diet to the brain and cognition: a review of proposed mechanisms.
Freeman LR; Haley-Zitlin V; Rosenberger DS; Granholm A-C
Editorial comment: JOURNAL OF NEUROSCIENCE METHODS. 2014;231:1-2
Motion capture and associated novel measurement devices for movement function in humans and animal models.
Karakostas T; Granholm A-C
Meeting abstract: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2012;206(1):s197
Adolescent cognitive and anxiety behavior in offspring following in utero exposure to increased trans unsaturated fatty acids through maternal diet
Alanis M; Umphlet C; Boger H; Granholm A-C
Editorial comment: NEUROPSYCHOPHARMACOLOGY. 2010;35(8):1621-1622
Why do we need to use animal models to study cognition and aging?
Granholm A-C
Published conference paper: PROGRESS IN NEUROBIOLOGY. 2010;90(2):217-229
A dual-hit animal model for age-related parkinsonism.
Boger HA; Granholm A-C; McGinty JF; Middaugh LD
Editorial comment: PROGRESS IN NEUROBIOLOGY. 2010;90(2):71-74
Chemical signaling in the nervous system in health and disease: Nils-Ake Hillarp's legacy Introduction
Granholm A-C; Skirboll L; Schultzberg M
Published conference paper: NEUROTOXICOLOGY. 2008;29(5):864-870
Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits.
Liu Y; Qin L; Wilson B; Wu X; Qian L; Granholm A-C; Crews FT; Hong J-S
Review: CURRENT AGING SCIENCE. 2008;1(2):133-139
Mood, memory and movement: an age-related neurodegenerative complex?
Granholm A-C; Boger H; Emborg ME
Published conference paper: CELL TRANSPLANTATION. 2007;16(3):197-205
Galantamine effects on memory, spatial cue utilization, and neurotrophic factors in aged female rats.
French KL; Bimonte-Nelson HA; Granholm AC
Review: PROGRESS IN NEUROBIOLOGY. 2006;80(3):114-128
Nerve growth factor in treatment and pathogenesis of Alzheimer's disease
Williams BJ; Eriksdotter-Jonhagen M; Granholm A-C
Meeting abstract: EXPERIMENTAL NEUROLOGY. 2006;198(2):594
Dietary supplementation with blueberry extract attenuates the age-associated increase in microglial activation
Willis LM; Bickford PC; Stromberg I; Granholm AC
Meeting abstract: EXPERIMENTAL NEUROLOGY. 2006;198(2):578
APP accumulation and inflammation in the Ts65dn mouse, a model for Down's syndrome
Lockrow J; Willis L; Granholm AC; Sambamurti K
Other: ALZHEIMER'S AND DEMENTIA. 2005;1(1):53-54
Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, Luigi Puglielli.
Granholm A-C; Bachman D; Mintzer J; Sambamurti K
Published conference paper: CELL TRANSPLANTATION. 2005;14(4):213-223
Blueberry extract enhances survival of intraocular hippocampal transplants.
Willis L; Bickford P; Zaman V; Moore A; Granholm A-C
Review: CURRENT DRUG TARGETS. 2004;5(6):517-528
Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors.
Sambamurti K; Granholm A-C; Kindy MS; Bhat NR; Greig NH; Lahiri DK; Mintzer JE
Published conference paper: CELL TRANSPLANTATION. 2003;12(3):291-303
The Noradrenergic System of Aged GDNF Heterozygous Mice.
Zaman V; Li Z; Middaugh L; Ramamoorthy S; Rohrer B; Nelson ME; Tomac AC; Hoffer BJ; Gerhardt GA; Granholm AC
Editorial comment: TRENDS IN NEUROSCIENCES. 2002;25(2):79-84
Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh.
Isacson O; Seo H; Lin L; Albeck D; Granholm AC
Published conference paper: CELL TRANSPLANTATION. 2002;11(3):215-227
Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion.
McGrath J; Lintz E; Hoffer BJ; Gerhardt GA; Quintero EM; Granholm A-C
Editorial comment: MICROSCOPY RESEARCH AND TECHNIQUE. 2001;54(5):271-272
Introduction:: Factors influencing neurite outgrowth and regeneration
Granholm AC; Strömberg I
Published conference paper: EXPERIMENTAL NEUROLOGY. 2000;164(1):45-52
Long-term environmental enrichment leads to regional increases in neurotrophin levels in rat brain
Ickes BR; Pham TM; Sanders LA; Albeck DS; Mohammed AH; Granholm AC
Review: EXPERT OPINION ON INVESTIGATIONAL DRUGS. 2000;9(4):685-694
Oestrogen and nerve growth factor - neuroprotection and repair in Alzheimer's disease.
Granholm AC
Editorial comment: CELL TRANSPLANTATION. 1999;8(1):7-9
Fifth Annual Meeting of the American Society for Neural Transplantation and Repair.
Granholm A-C; Emerich D
Published conference paper: CELL TRANSPLANTATION. 1999;8(1):75-85
Effects of osteogenic protein-1 (OP-1) treatment on fetal spinal cord transplants to the anterior chamber of the eye.
Granholm AC; Sanders LA; Ickes B; Albeck D; Hoffer BJ; Young DA; Kaplan PL
Published conference paper: CELL TRANSPLANTATION. 1998;7(2):197-212
Kidney cografts enhance fiber outgrowth from ventral mesencephalic grafts to the 6-OHDA-lesioned striatum, and improve behavioral recovery.
Granholm AC; Henry S; Herbert MA; Eken S; Gerhardt GA; van Horne C
Review: REVIEWS IN THE NEUROSCIENCES. 1998;9(1):31-56
A non-invasive system for delivering neural growth factors across the blood-brain barrier: a review.
Granholm AC; Albeck D; Bäckman C; Curtis M; Ebendal T; Friden P; Henry M; Hoffer B; Kordower J; Rose GM; Söderström S; Bartus RT
Editorial comment: CELL TRANSPLANTATION. 1996;5(2):127-130
Second annual meeting of the American Society for Neural Transplantation.
Granholm AC
Published conference paper: CELL TRANSPLANTATION. 1996;5(2):305-314
Development of an intact blood-brain barrier in brain tissue transplants is dependent on the site of transplantation.
Granholm AC; Curtis M; Diamond DM; Branch BJ; Heman KL; Rose GM
Published conference paper: COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY. 1996;61:445-457
GDNF is required for kidney development and enteric innervation.
Pichel JG; Shen L; Sheng HZ; Granholm AC; Drago J; Grinberg A; Lee EJ; Huang SP; Saarma M; Hoffer BJ; Sariola H; Westphal H
Published conference paper: CELL TRANSPLANTATION. 1995;4(1):3-12
Synapsin I in intraocular hippocampal transplants during maturation and aging: effects of brainstem cografts.
Granholm AC; Bergman H; Dudek E; Browning M
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