Anders Lindén

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Anders Lindén är professor i lung- och luftvägsforskning vid Institutet för miljömedicin (IMM). Hans huvudsakliga forskningsområde är brister i lungornas lokala immunsystem hos rökare med och utan lungsjukdomen KOL. Forskningen berör även svår/kronisk astma, en sjukdom som har vissa likheter med KOL.

Artiklar

Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(22):4095-4104
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak MJ; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas EI; Villa V; Ricciarelli R; Sandberg JK; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay AJ; Pernemalm M; Lindeen A; Klingstrom J; El Andaloussi S; Ezzat K
Article: RESPIRATORY RESEARCH. 2024;25(1):163
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Kaeck U; Che KF; Brundin B; Konradsen JR; Linden A
Article: RESPIRATORY RESEARCH. 2024;25(1):86
Large airway T cells in adults with former bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Kaarteenaho R; Reinke NS; Wheelock CE; Melen E; Anders L; Wheelock AM; Rassidakis G; Ortiz-Villalon C; Skold MC
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1434186
Systemic increase in IL-26 is associated with severe COVID-19 and comorbid obstructive lung disease
Cardenas EI; Robertson J; Misaghian S; Brown J; Wang M; Stengelin M; Sigal G; Wohlstadter J; Gisslen M; Linden A
Article: GLYCOBIOLOGY. 2023;33(12):1128-1138
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD
Venkatakrishnan V; Thomsson KA; Padra M; Andersson A; Brundin B; Christenson K; Bylund J; Karlsson NG; Linden A; Linden SK
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2023;10(1):2181291
Comorbid conditions as predictors of mortality in severe COPD - an eight-year follow-up cohort study
Eliasson G; Janson C; Johansson G; Larsson K; Linden A; Loefdahl C-G; Sandstroem T; Sundh J
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1178135
TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26
Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis
Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;60(3):2102531
Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
Um-Bergstrom P; Pourbazargan M; Brundin B; Strom M; Ezerskyte M; Gao J; Brostrom EB; Melen E; Wheelock AM; Linden A; Skold CM
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:1179-1194
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
Pournaras N; Andersson A; Kovach MA; Padra M; Che KF; Brundin B; Yoshihara S; Bozinovski S; Linden SK; Jansson P-A; Skold MC; Qvarfordt I; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:993-1004
Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)
Lundh L; Larsson K; Linden A; Montgomery S; Palmberg L; Sandelowsky H
Article: RESPIRATORY RESEARCH. 2022;23(1):108
Involvement of IL-26 in bronchiolitis obliterans syndrome but not in acute rejection after lung transplantation
Magnusson JM; Ericson P; Tengvall S; Stockfelt M; Brundin B; Linden A; Riise GC
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2022;16(3):293-301
IL-26 in asthma and COPD
Cardenas EI; Che KF; Konradsen JR; Bao A; Linden A
Article: LAKARTIDNINGEN. 2022;119:21155
[Pharmacological treatment reduces mortality in COPD].
Larsson K; Lindberg A; Sandelowsky H; Lindén A; Ställberg B; Janson C
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1016991
Increased IL-26 associates with markers of hyperinflammation and tissue damage in patients with acute COVID-19
Cardenas EI; Ekstedt S; Piersiala K; Petro M; Karlsson A; Kagedal A; Georen SK; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;65(6):593-602
Mucin Binding to Moraxella catarrhalis during Airway Inflammation Is Dependent on Sialic Acid
Padra M; Benktander J; Padra JT; Andersson A; Brundin B; Tengvall S; Christenson K; Qvarfordt I; Gad R; Paulsson M; Pournaras N; Linden A; Linden SK
Article: ENVIRONMENTAL RESEARCH. 2021;200:111739
Occupational exposure to particles and increased risk of developing chronic obstructive pulmonary disease (COPD): A population-based cohort study in Stockholm, Sweden
Grahn K; Gustavsson P; Andersson T; Linden A; Hemmingsson T; Selander J; Wiebert P
Article: RESPIRATORY RESEARCH. 2021;22(1):174
Heparin-binding protein in lower airway samples as a biomarker for pneumonia
Paulsson M; Thelaus L; Riesbeck K; Qvarfordt I; Smith ME; Linden A; Linder A
Article: EUROPEAN RESPIRATORY JOURNAL. 2021;57(3):2002120
Assessment of chronic bronchitis and risk factors in young adults: results from BAMSE.
Wang G; Hallberg J; Um Bergström P; Janson C; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Bergström A; Kull I; Lindén A; Melén E
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2021;41(2):181-191
The ratio FEV₁/FVC and its association to respiratory symptoms-A Swedish general population study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall JE; Eriksson MJ; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Lennart Persson H; Sandelin M; Eriksson Strom J; Tanash H; Vikgren J; Johan Ostgren C; Wollmer P; Skold CM
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2021;16:367-377
Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations
Sundqvist M; Andelid K; Ekberg-Jansson A; Bylund J; Karlsson-Bengtsson A; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;64(2):173-182
IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers
Kovach MA; Che K; Brundin B; Andersson A; Asgeirsdottir H; Padra M; Linden SK; Qvarfordt I; Newstead MW; Standiford TJ; Linden A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:761317
Complex Involvement of Interleukin-26 in Bacterial Lung Infection
Che KF; Paulsson M; Piersiala K; Sax J; Mboob I; Rahman M; Rekha RS; Safholm J; Adner M; Bergman P; Cardell L-O; Riesbeck K; Linden A
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S2)
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Malm T; Gustafsson O; Lindén A; Andaloussi SEL
Article: LAKARTIDNINGEN. 2020;117:20051
[The role of inhaled steroids in the treatment of COPD].
Ställberg B; Janson C; Lindén A; Lisspers K; Larsson K
Article: BMJ OPEN RESPIRATORY RESEARCH. 2020;7(1):e000600
Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Persson HL; Sandelin M; Strom JE; Tanash HA; Vikgren J; Ostgren CJ; Wollmer P; Skold CM
Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(5):1869-1879
Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Szmidt MK; Kaluza J; Harris HR; Linden A; Wolk A
Article: CLINICAL SCIENCE. 2020;134(10):1107-1125
Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers
Padra M; Andersson A; Levanen B; Premaratne P; Asgeirsdottir H; Tengvall S; Christenson K; Stockfelt M; Bozinovski S; Yoshihara S; Lantz A-S; Palmberg L; Dahlen B; Larsson K; Qvarfordt I; Linden SK; Linden A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Article: FRONTIERS IN NEUROSCIENCE. 2020;14:256
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Sturchio A; Graff C; Espay AJ; Wright AP; El Andaloussi S; Linden A; Ezzat K
Article: JOURNAL OF INNATE IMMUNITY. 2020;12(6):480-489
Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD
Stockfelt M; Christenson K; Andersson A; Bjorkman L; Padra M; Brundin B; Ganguly K; Asgeirsdottir H; Linden S; Qvarfordt I; Bylund J; Linden A
Journal article: REVUE DES MALADIES RESPIRATOIRES ACTUALITES. 2020;12(1):96
Aucune augmentation d’interleukin-4 et de protéine cationique des éosinophiles (ECP) dans le plasme durant des exacerbations BPCO
Andersson A; Andelid K; Levänen B; Lindén A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):1134-1136.e10
Enhanced local production of IL-26 in uncontrolled compared with controlled adult asthma
Tufvesson E; Jogdand P; Che KF; Levanen B; Erjefalt JS; Bjermer L; Linden A
Article: NATURE COMMUNICATIONS. 2019;10(1):2331
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Pernemalm M; Palsson S; Roberts TC; Jarver P; Dondalska A; Bestas B; Sobkowiak MJ; Levanen B; Skold M; Thompson EA; Saher O; Kari OK; Lajunen T; Ekstrom ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power UF; Masich S; Linden A; Sandberg JK; Lehtio J; Spetz A-L; EL Andaloussi S
Article: RESPIRATORY RESEARCH. 2019;20(1):102
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(5):907-916
Alcohol Consumption and Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Harris HR; Linden A; Wolk A
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(2):665-672
Long-term unprocessed and processed red meat consumption and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris H; Linden A; Wolk A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:956
Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
Che KF; Sun J; Linden A
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(6):1897-1909
Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris HR; Linden A; Wolk A
Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy563.p3645
P3645Interleukin 8 (IL-8), but not GRO-a, associates with carotid intima-media thickness. Results from the IMPROVE study
Velasquez IM; Malarstig A; Baldassarre D; Silveira A; Veglia F; Leander K; Tremoli E; Humphries S; Linden A; Hamsten A; De Faire U; Strawbridge RJ; Gigante B; IMPROVE
Article: CLINICAL SCIENCE. 2018;132(9):959-983
The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers
Che KF; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold CM; Linden A
Article: EPIDEMIOLOGY. 2018;29(2):254-260
Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease A Prospective Cohort Study of Men
Kaluza J; Harris H; Wallin A; Linden A; Wolk A
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:1559
Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing
Paulsson M; Che KF; Ahi J; Tham J; Sandblad L; Smith ME; Qvarfordt I; Su Y-C; Linden A; Riesbeck K
Article: MOLECULAR MEDICINE. 2017;23:247-257
Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: THORAX. 2017;72(6):500-509
Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men
Kaluza J; Larsson SC; Orsini N; Linden A; Wolk A
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2017;4(1):1270079
Characterization of secondary care for COPD in Sweden
Sundh J; Janson C; Johansson G; Linden A; Lofdahl C-G; Sandstrom T; Larsson K
Journal article: REVUE DES MALADIES RESPIRATOIRES. 2017;34:a162
Le taux des éosinophiles du sang périphérique est baissé pendant des exacerbations de BPCO
Andersson A; Andelid K; Lindén A
Article: JOURNAL OF INNATE IMMUNITY. 2017;9(5):475-482
Endotoxin Exposure Increases LL-37-but Not Calprotectin - in Healthy Human Airways
Smith ME; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Article: PLOS ONE. 2017;12(12):e0188909
Recombinant human IL-26 facilitates the innate immune response to endotoxin in the bronchoalveolar space of mice in vivo
Bao A; Che KF; Bozinovski S; Ji J; Gregory JA; Georen SK; Adner M; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2016;184(11):829-836
Consumption of Unprocessed and Processed Red Meat and the Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Larsson SC; Linden A; Wolk A
Journal article: CIRCULATION. 2016;134(suppl_1)
Abstract 13512: Chemokines and Carotid Intima-Media Thickness in a European Population at High Risk for Cardiovascular Events: Results From the IMPROVE Study
Moreno Velasquez I; Malarstig A; Strawbridge RJ; Baldassarre D; Veglia F; Leander K; Silveira A; Rauramaa R; Smit AJ; Giral P; Mannarino E; Tremoli E; Humphries SE; Lindén A; Hamsten A; de Faire U; Gigante B
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2245-2258
Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
Andersson A; Malmhall C; Houltz B; Tengvall S; Sjostrand M; Qvarfordt I; Linden A; Bossios A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2109-2116
Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways
Levanen B; Glader P; Dahlen B; Billing B; Qvarfordt I; Palmberg L; Larsson K; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1005-1013
Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
Sundblad B-M; Ji J; Levanen B; Midander K; Julander A; Larsson K; Palmberg L; Linden A
Article: RESPIRATORY RESEARCH. 2016;17:32
The cytokine interleukin-26 as a biomarker in pediatric asthma
Konradsen JR; Nordlund B; Levanen B; Hedlin G; Linden A
Article: PLOS ONE. 2016;11(10):e0164751
Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function
Ostadkarampour M; Muller M; Ockinger J; Kullberg S; Linden A; Eklund A; Grunewald J; Wahlstrom J
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:2327-2334
The phenotype of concurrent chronic bronchitis and frequent exacerbations in patients with severe COPD attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Sandstrom T; Janson C
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:1253-1263
Systemic signs of neutrophil mobilization during clinically stable periods and during exacerbations in smokers with obstructive pulmonary disease
Andelid K; Andersson A; Yoshihara S; Ahren C; Jirholt P; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:689-702
Systemic cytokine signaling via IL-17 in smokers with obstructive pulmonary disease: a link to bacterial colonization?
Andelid K; Tengvall S; Andersson A; Levanen B; Christenson K; Jirholt P; Ahren C; Qvarfordt I; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:173-183
Comorbidity and health-related quality of life in patients with severe chronic obstructive pulmonary disease attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Janson C; Sandstrom T
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;190(9):1022-1031
Interleukin-26 in Antibacterial Host Defense of Human Lungs Effects on Neutrophil Mobilization
Che KF; Tengvall S; Levanen B; Silverpil E; Smith ME; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(5):1319-1331
Interleukin-17 cytokine signalling in patients with asthma
Linden A; Danlen B
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;178(2):342-352
Higher levels of interleukin IL-17 and antigen-specific IL-17 responses in pulmonary sarcoidosis patients with Lofgren's syndrome
Ostadkarampour M; Eklund A; Moller D; Glader P; Hoglund CO; Linden A; Grunewald J; Wahlstrom J
Journal article: RESPIRATORY MEDICINE. 2013;107(11):s4
Systemic myeloperoxidase in COPD
Andelid K; Glader P; Jirholt P; Gjertsson I; Jansson AE; Lindén A
Article: INNATE IMMUNITY. 2013;19(5):479-492
Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation
Silverpil E; Wright AKA; Hansson M; Jirholt P; Henningsson L; Smith ME; Gordon SB; Iwakura Y; Gjertsson I; Glader P; Linden A
Article: INFLAMMATION RESEARCH. 2013;62(6):561-569
Interleukin-22 produced by alveolar macrophages during activation of the innate immune response
Hansson M; Silverpil E; Linden A; Glader P
Article: PLOS ONE. 2013;8(9):e75032
Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects
Smith ME; Bozinovski S; Malmhall C; Sjostrand M; Glader P; Venge P; Hiemstra PS; Anderson GP; Linden A; Qvarfordt I
Journal article: PNEUMOLOGIE. 2012;66(11)
IL-17 and antigen-specific IL-17 responses in distinct subsets of patients with pulmonary sarcoidosis
Ostadkarampour M; Eklund A; Moller D; Glader P; Lindén A; Grunewald J; Wahlström J
Article: LAKARTIDNINGEN. 2011;108(35):1604-1605
[How the care of COPD will be better].
Larsson K; Löfdahl C-G; Lindén A; Sandström T; Johansson GS
Article: INNATE IMMUNITY. 2011;17(2):204-211
¹H and hyperpolarized ³He magnetic resonance imaging clearly detect the preventative effect of a glucocorticoid on endotoxin-induced pulmonary inflammation in vivo
Olsson LE; Smailagic A; Onnervik P-O; Linden A; Hockings PD
Article: INFLAMMATION. 2011;34(1):1-9
Impact of Interleukin-17 on Macrophage Phagocytosis of Apoptotic Neutrophils and Particles
Silverpil E; Glader P; Hansson M; Linden A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2011;300(1):L43-L55
Effects of tobacco smoke on IL-16 in CD8⁺ cells from human airways and blood: a key role for oxygen free radicals?
Andersson A; Bossios A; Malmhall C; Sjostrand M; Eldh M; Eldh B-M; Glader P; Andersson B; Qvarfordt I; Riise GC; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2011;6:83-88
A gender difference in circulating neutrophils in malnourished patients with COPD
Larsson S; Nordenson A; Glader P; Yoshihara S; Linden A; Slinde F
Article: EUROPEAN RESPIRATORY JOURNAL. 2010;36(5):1155-1164
Interleukin-17-producing T-helper cells and related cytokines in human airways exposed to endotoxin
Glader P; Smith ME; Malmhall C; Balder B; Sjostrand M; Qvarfordt I; Linden A
Article: INFECTION AND IMMUNITY. 2010;78(9):3783-3790
Interleukin-17A during Local and Systemic Staphylococcus aureus-Induced Arthritis in Mice
Henningsson L; Jirholt P; Lindholm C; Eneljung T; Silverpil E; Iwakura Y; Linden A; Gjertsson I
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;182(1):34-40
Neutralizing Granulocyte/Macrophage Colony-Stimulating Factor Inhibits Cigarette Smoke-induced Lung Inflammation
Vlahos R; Bozinovski S; Chan SPJ; Ivanov S; Linden A; Hamilton JA; Anderson GP
Article: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010;29(7):800-807
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome
Riise GC; Ericson P; Bozinovski S; Yoshihara S; Anderson GP; Linden A
Article: RESPIRATORY RESEARCH. 2009;10(1):94
West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma
Lotvall J; Ekerljung L; Ronmark EP; Wennergren G; Linden A; Ronmark E; Toren K; Lundback B
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2009;22(3):199-207
IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy
Prause O; Bossios A; Silverpil E; Ivanov S; Bozinovski S; Vlahos R; Sjostrand M; Anderson GP; Linden A
Journal article: JOURNAL OF IMMUNOLOGY. 2009;182(1_Supplement):134.32
IL-17-induced apoptosis correlates positively with the release of myeloperoxidase in isolated neutrophils from mice (134.32)
Silverpil E; Glader P; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(3):644-650
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
Glader P; Eldh B; Bozinovski S; Andelid K; Sjostrand M; Malmhall C; Anderson GP; Riise GC; Qvarfordt I; Linden A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(5):480-488
Prolonged eosinophil production after allergen exposure in IFN-γR KO mice is IL-5 dependent
Zhao L-L; Lotvall J; Linden A; Tomaki M; Sjostrand M; Bossios A
Journal article: RESPIRATORY MEDICINE: COPD UPDATE. 2007;3(4):123
Impact of tobacco smoke on Interleukin-16 protein in human airways and lymphocytes
Andersson A; Sjöstrand M; Qvarfordt I; Riise G; Laan M; Malmhäll C; Lindén A
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2007;1(2):279-293
Th-17 cells in the lungs?
Ivanov S; Lindén A
Article: RESPIRATORY MEDICINE. 2007;101(5):888-895
Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms
Andelid K; Bake B; Rak S; Linden A; Rosengren A; Ekberg-Jansson A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2007;36(4):442-451
Functional relevance of the IL-23-IL-17 axis in lungs in vivo
Ivanov S; Bozinovski S; Bossios A; Valadi H; Vlahos R; Malmhall C; Sjostrand M; Kolls JK; Anderson GP; Linden A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2006;144(2):212-216
Association of epithelial damage and signs of neutrophil mobilization in the airways during acute exacerbations of paediatric asthma
Yoshihara S; Yamada Y; Abe T; Lindén A; Arisaka O
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2006;19(1):47-50
Interleukin-17 and airway remodelling
Lindén A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2005;33(3):248-253
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation
Sergejeva S; Ivanov S; Lötvall J; Lindén A
Article: RESPIRATORY RESEARCH. 2005;6(1):44
Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust -: art. no. 44
Ivanov S; Palmberg L; Venge P; Larsson K; Lindén A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;138(1):75-82
Impact of tobacco smoke on interleukin-16 protein in human airways, lymphoid tissue and T lymphocytes
Andersson A; Qvarfordt I; Laan M; Sjöstrand M; Malmhäll C; Riise GC; Cardell LO; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2004;24(2):231-237
β-adrenoceptor stimulation and neutrophil accumulation in mouse airways
Miyamoto M; Tomaki M; Lötvall J; Lindén A
Article: THORAX. 2004;59(4):313-317
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
Prause O; Bozinovski S; Anderson GP; Lindén A
Article: REGULATORY PEPTIDES. 2004;117(2):149-154
A synthetic VIP peptide analogue inhibits neutrophil recruitment in rat airways in vivo
Sergejeva S; Hoshino H; Yoshihara S; Kashimoto K; Lötvall J; Lindén A
Article: RESPIRATORY MEDICINE. 2004;98(2):159-163
BAL levels of interleukin-18 do not change before or during acute rejection in lungtransplant recipients
Ericson P; Lindén A; Riise GC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;133(2):290-296
IL-16 in the airways of lung allograft recipients with acute rejection or obliterative bronchiolitis
Laan M; Lindén A; Riise GC
Article: JOURNAL OF IMMUNOLOGY. 2003;170(9):4665-4672
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways
Miyamoto M; Prause O; Sjöstrand M; Laan M; Lötvall J; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;21(3):387-393
A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF-α
Laan M; Prause O; Miyamoto M; Sjöstrand M; Hytönen AM; Kaneko T; Löotvall J; Lindén A
Article: THORAX. 2003;58(3):217-221
Bronchodilation by an inhaled VPAC₂ receptor agonist in patients with stable asthma
Lindén A; Hansson L; Andersson A; Palmqvist M; Arvidsson P; Löfdahl CG; Larsson P; Lötvall J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;462(1-3):193-198
Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells
Prause O; Laan M; Lötvall J; Lindén A
Journal article: ALLERGOLOGY INTERNATIONAL. 2003;52(4):173-182
Neutrophils, interleukin-17 and obstructive airway disease
Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(3):534-537
Free, soluble interleukin-17 protein during severe inflammation in human airways
Laan M; Palmberg L; Larsson K; Lindén A
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2002;15(2):161-168
Comparison of effects of Anti-IL-3, IL-5 and GM-CSF treatments on eosinophilopoiesis and airway eosinophilia induced by allergen
Tomaki M; Zhao LL; Sjöstrand M; Lindén A; Ichinose M; Lötvall J
Article: PEPTIDES. 2001;22(12):2151-2154
Pituitary adenylate cyclase-activating peptide inhibits neutrophil chemotaxis
Kinhult J; Uddman R; Laan M; Lindén A; Cardell LO
Article: ALLERGY. 2001;56(9):871-877
Effect of seasonal allergen exposure on mucosal IL-16 and CD4+cells in patients with allergic rhinitis
Pullerits T; Lindén A; Malmhäll C; Lötvall J
Article: EUROPEAN RESPIRATORY JOURNAL. 2001;17(5):872-880
Reduced late asthmatic response by repeated low-dose allergen exposure
Palmqvist M; Cui ZH; Sjöstrand M; Lindén A; Lötvall J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2001;133(1):200-206
IL-17-induced cytokine release in human bronchial epithelial cells in vitro:: role of mitogen-activated protein (MAP) kinases
Laan M; Lötvall J; Chung KF; Lindén A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1469-1475
Upregulation of nasal mucosal eotaxin in patients with allergic rhinitis during grass pollen season:: effect of a local glucocorticoid
Pullerits T; Lindén A; Praks L; Cardell LO; Lötvall J
Article: JOURNAL OF IMMUNOLOGY. 2000;165(7):4040-4050
Eosinophilopoiesis in a murine model of allergic airway eosinophilia:: Involvement of bone marrow IL-5 and IL-5 receptor α
Tomaki M; Zhao LL; Lundahl J; Sjöstrand M; Jordana M; Lindén A; O'Byrne P; Lötvall J
Article: ALLERGY. 2000;55(8):749-756
IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure
Zhao LL; Lindén A; Sjöstrand M; Cui ZH; Lötvall J; Jordana M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):143-149
Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo
Hoshino H; Laan M; Sjöstrand M; Lötvall J; Skoogh BE; Lindén A
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s294
863 Attenuation of early phase airway response and plasma exudation due to reduction of leukotrines production after repeated allergen exposure
Cui Z-H; Pullerits T; Linden A; Skoogh B-E; Lotvall J
Article: THORAX. 1999;54(10):911-916
Increased levels of interleukin-16 in the airways of tobacco smokers:: relationship with peripheral blood T lymphocytes
Laan M; Qvarfordt I; Riise GC; Andersson BA; Larsson S; Lindén A
Article: REGULATORY PEPTIDES. 1999;81(1-3):49-53
Effect of nedocromil sodium on non-adrenergic, non-cholinergic neural responses in guinea pig bronchi in vitro
Lindén A; Bergendal A; Lötvall J; Skoogh BE; Löfdahl CG
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;159(5):1423-1428
Neutrophil recruitment by interleukin-17 into rat airways in vivo -: Role of tachykinins
Hoshino H; Lötvall J; Skoogh BE; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 1999;162(4):2347-2352
Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
Laan M; Cui ZH; Hoshino H; Lötvall J; Sjöstrand M; Gruenert DC; Skoogh BE; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(5):1062-1066
Effect of a novel PACAP-27 analogue on muscarinic airway responsiveness in guinea-pigs in vivo
Okazawa A; Cui ZH; Lotvall J; Yoshihara S; Skoogh BE; Kashimoto K; Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1998;124(6):1065-1068
Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger
Cardell LO; Ueki IF; Stjärne P; Agusti C; Takeyama K; Lindén A; Nadel JA
Article: PEPTIDES. 1998;19(3):593-597
A novel long-acting VIP analog in the guinea pig trachea in vitro
Yoshihara S; Lindén A; Kashimoto K; Watanabe S
Article: PEPTIDES. 1998;19(1):93-98
PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo
Lindén A; Cardell LO; Yoshihara S; Stjärne P; Nadel JA
Article: BIOMEDICAL RESEARCH-TOKYO. 1998;19(1):39-44
Sustained relaxant action of [Arg^15,20,21, Leu¹⁷]-PACAP-27-NH₂ on carbachol-induced contraction of guinea-pig tracheal smooth muscle in vitro
Yamada Y; Yoshihara S; Kashimoto K; Linden A; Ichimura T
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(8):1730-1734
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro
Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Article: PEPTIDES. 1997;18(6):843-846
Functional type II VIP-PACAP receptors in human airway epithelial-like cells
Linden A; Yoshihara S; Cardell LO; Kaneko T; Stjarne P; Nadel JA
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(5):L838-L843
Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways
Massion PP; Linden A; Inoue H; Mathy M; Grattan KM; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;119(2):402-406
Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells
Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;117(6):1009-1015
Extent of salmeterol-mediated reassertion of relaxation in guineapig trachea pretreated with aliphatic side chain structural analogues
Bergendal A; Linden A; Skoogh BE; Gerspacher M; Anderson GP; Lofdahl CG
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;97(3):756-760
Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs
Yoshihara S; Geppetti P; Lindan A; Hara M; Chan BD; Nadel JA
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;296(3):291-296
Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs
Yoshihara S; Geppetti P; Hara M; Linden A; Ricciardolo FLM; Chan B; Nadel JA
Article: LUNG. 1996;174(3):159-170
Relaxation kinetics of formoterol and salmeterol in the guinea pig trachea in vitro
Anderson P; Lotvall J; Linden A
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;280(2):113-118
CORTICOTROPIN-RELEASING FACTOR INHIBITS ANTIGEN-INDUCED PLASMA EXTRAVASATION IN AIRWAYS
YOSHIHARA S; RICCIARDOLO FLM; GEPPETTI P; LINDEN A; HARA M; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;115(6):913-916
INHIBITION OF BRONCHOCONSTRICTION BY PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP-1-27) IN GUINEA-PIGS IN-VIVO
LINDEN A; YOSHIHARA S; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;114(7):1478-1482
DIFFERENT EFFECTS OF SALMETEROL, FORMOTEROL AND SALBUTAMOL ON CHOLINERGIC RESPONSES IN THE FERRET TRACHEA
BERGENDAL A; LINDEN A; LOTVALL J; SKOOGH BE; LOFDAHL CG
Journal article: CLINICAL AND EXPERIMENTAL ALLERGY. 1994;24(6):582-589
ROLE OF EICOSANOIDS IN AIR-FLOW OBSTRUCTION AND AIRWAY PLASMA EXUDATION INDUCED BY TRIMELLITIC ANHYDRIDE-CONJUGATE IN GUINEA-PIGS 3 AND 8 WEEKS AFTER SENSITIZATION
ARAKAWA H; LOTVALL J; LINDEN A; KAWIKOVA I; LOFDAHL CG; SKOOGH BE
Journal article: RESPIRATORY MEDICINE. 1994;88(4):249-265
NANC RESPONSES - ROLE IN CONTROL OF AIRWAY TONE
LINDEN A; SKOOGH BE
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1994;7(3):569-578
WHY ARE LONG-ACTING BETA-ADRENOCEPTOR AGONISTS LONG-ACTING
ANDERSON GP; LINDEN A; RABE KF
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1993;109(3):845-851
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION IN GUINEA-PIG BRONCHI - POWERFUL AND FREQUENCY-DEPENDENT STABILIZING EFFECT ON TONE
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: THORAX. 1993;48(5):547-553
SALMETEROL, FORMOTEROL, AND SALBUTAMOL IN THE ISOLATED GUINEA-PIG TRACHEA - DIFFERENCES IN MAXIMUM RELAXANT EFFECT AND POTENCY BUT NOT IN FUNCTIONAL ANTAGONISM
LINDEN A; BERGENDAL A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1993;6(3):425-433
NONADRENERGIC, NONCHOLINERGIC RESPONSES STABILIZE SMOOTH-MUSCLE TONE, WITH AND WITHOUT PARASYMPATHETIC ACTIVATION, IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: ALLERGY. 1992;47(4):384-387
ONSET OF ACTION AND DURATION OF EFFECT OF FORMOTEROL AND SALMETEROL COMPARED TO SALBUTAMOL IN ISOLATED GUINEA-PIG TRACHEA WITH OR WITHOUT EPITHELIUM
ULLMAN A; BERGENDAL A; LINDEN A; WALDECK B; SKOOGH BE; LOFDAHL CG
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1992;71(1):41-44
INVITRO TACHYPHYLAXIS TO ISOPRENALINE IN GUINEA-PIG TRACHEA - INFLUENCE OF THEOPHYLLINE
BERGENDAL A; LINDEN A; LOTVALL J; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1992;106(3):616-622
THE NONADRENERGIC, NONCHOLINERGIC RESPONSE COUNTERACTS CHANGES IN GUINEA-PIG AIRWAY TONE WITH AND WITHOUT SYMPATHETIC ACTIVATION
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1991;104(2):509-513
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION STABILIZES SMOOTH-MUSCLE TONE INDEPENDENTLY OF EICOSANOID FACTORS IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: ACTA PHYSIOLOGICA. 1991;142(3):351-357
INVITRO CHARACTERISTICS OF SPONTANEOUS AIRWAY TONE IN THE GUINEA-PIG
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: PULMONARY PHARMACOLOGY. 1991;4(3):170-176
NONADRENERGIC, NONCHOLINERGIC REGULATION OF GUINEA-PIG AIRWAY SMOOTH-MUSCLE INDOMETHACIN-INDUCED CHANGES AND SEGMENTAL DIFFERENCES
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: PULMONARY PHARMACOLOGY. 1990;3(3):155-160
Epithelium-derived PGE2 inhibits the contractile response to cholinergic stimulation in isolated ferret trachea.
Ullman A; Ciabattoni G; Löfdahl CG; Lindén A; Svedmyr N; Skoogh BE
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Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4192
Microbiology in Swedish patients with bronchiectasis and comorbid airway disease: Data from a tertiary European Bronchiectasis registry (EMBARC) center
Osman N; Ghosh P; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3319
Infection with P. aeruginosa and H. influenzae in relation to QoL and symptoms in bronchiectasis patients requiring intravenous antibiotics; data from a European Bronchiectasis Registry (EMBARC) center.
Ghosh P; Osman N; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa1227
Assessment of small airway dysfunction and symptoms in COPD
Lazarinis N; Panagiotou A; Ramos Ramirez P; Ehlin A; Ridderby A; Pournaras N; Bossios A; Linden A
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2024;18(7):539-552
Small airways disease in chronic obstructive pulmonary disease
Lazarinis N; Fouka E; Linden A; Bossios A
Preprint: RESEARCH SQUARE. 2023
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Käck U; Che KF; Brundin B; Konradsen JR; Linden A
Preprint: AUTHOREA. 2023
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Käck U; F KC; Brundin B; Konradsen JR; Lindén A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a4790
Regulatory T Cells Expressing Toll-like Receptor 2 in Blood From Smokers With Stable Chronic Obstructive Pulmonary Disease
Linden A; Malmhall C; Molnar A; Andersson A; Sjostrand M; Bossios A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a2520
The Anti-inflammatory Club Cell Protein 16 Is Decreased in Human Airways After Intrabronchial Lipopolysaccharide (LPS) Exposure
Cardenas EI; Smith M; Qvarfordt I; Linden A
Preprint: BIORXIV. 2022
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak M; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas E; Villa V; Ricciarelli R; Sandberg J; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay A; Pernemalm M; Lindén A; Klingström J; El Andaloussi S; Ezzat K
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a2410
Glucose Turnover and Neutrophil-Related Cytokines in Smokers With and Without Chronic Obstructive Pulmonary Disease
Pournaras N; Andersson A; Melissa K; Padra M; Che KF; Brundin B; Bozinovski S; Linden K; Jansson P; Skold M; Qvarfordt I; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a1976
Increased Cytotoxic T Cells in the Large Airways in Adults Born Prematurely with a History of Bronchopulmonary Dysplasia
Gao J; Um-Bergstrom PJ; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Riitta K; Reinke S; Wheelock CE; Melen E; Linden A; Wheelock AM; Rassidaki G; Ortiz-Villalon C; Skold CM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a2203
Heparin-Binding Protein Is Increased in the Lung After Intrabronchial Endotoxin Exposure
Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Editorial comment: RESPIROLOGY. 2021;26(11):1012-1013
IL-17A: A promising target in viral lung infections
Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:pa3829
Systemic interleukin-26 relates to the risk of exacerbations in smokers with COPD and chronic bronchitis
Lundgren R; Andelid K; Ezerskyte M; Pournaras N; Brundin B; Che KF; Linden A
Editorial comment: THORAX. 2021;76(5):503-507
Early-life risk factors for reversible and irreversible airflow limitation in young adults: findings from the BAMSE birth cohort
Wang G; Kull I; Bergstrom A; Hallberg J; Bergstrom PU; Guerra S; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Janson C; Linden A; Melen E
Review: CYTOKINE & GROWTH FACTOR REVIEWS. 2021;57:1-10
Interleukin-26 in host defense and inflammatory disorders of the airways
Che KF; Tengvall S; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:3371
Structural changes on high resolution computed tomography (HRCT) in adult individuals with a history of bronchopulmonary dysplasia (BPD)
Pourbazargan M; Nyren S; Um-Bergstrom P; Berggren-Brostrom E; Melen E; Steern R; Wheelock AM; Linden A; Karimi R; Skold CM
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:432
Assessment of chronic bronchitis in young adults - results from the BAMSE cohort
Wang G; Hallberg J; Bergstrom PU; Janson C; Pershagen G; Georgelis A; Bergstrom A; Kull I; Linden A; Melen E
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2333
Klebsiella pneumonae triggers rapid release IL(IL)-26 in human neutrophils
Che K; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2020;201:a3989
Priming with RhIL-26 Modulates the Cytokine Response to Klebsiella Pneumoniae in Monocyte-Derived Macrophages
Che KF; Rekha R; Bergman P; Linden A
Preprint: PREPRINTS.ORG. 2019
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Wright A; Andaloussi SE; Linden A; Ezzat K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa3320
Chronic airflow limitation and respiratory symptoms among smokers and never smokers
Toren KO; Schioler L; Lindberg A; Andersson A; Behndig A; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Johnsson A; Lindberg E; Linden A; Malinovschi A; Persson L; Tanash H; Vikgren J; Ostgren C-J; Wollmer P; Sandelin M; Strom J; Skold M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa5453
The release of interleukin-26 from alveolar type II cells and its response to stimuli from Gram-negative and Gram-positive bacteria
Tabacaru G; Linden A; Che K
Conference publication: 2019;:pa4349
Alterations in measures of systemic inflammation among adults born preterm
Gao J; Um-Bergström P; Pourbazargan M; Berggren-Broström E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock C; Melén E; Lindén A; Wheelock A; Sköld M
Conference publication: 2019;:PA4317
Glucose tolerance and mobilization of neutrophils in smokers with and without chronic obstructive pulmonary disease
Pournaras N; Andersson A; Kovach M; Ganguly K; Padra M; Asgeirsdottir H; Che K; Levänen B; Lindén S; Jansson P-A; Qvarfordt I; Lindén A
Preprint: PREPRINTS.ORG. 2019
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Wright A; Andaloussi SE; Linden A; Ezzat K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa5480
Interleukin-26 in airway morbidities of long-term tobacco smokers
Che K; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold MC; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa960
T-cell subsets in bronchoalveolar lavage fluid from adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Pourbazargan M; Levanen B; Strom M; Berggren-Brostroom E; Melen E; Wheelock A; Linden A; Skold M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1376
Late Breaking Abstract - Systemic IL-26 correlates with improved asthma control in children with allergic sensitization
Kovach M; Kack U; Che K; Levanen B; Lilja G; Konradsen J; Linden A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1980
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson M; Nyren S; Lilja G; Linden A; Wheelock A; Melen E; Skold M
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:oa4920
Late Breaking Abstract - Elevated airway lymphocytes in adults born prematurely with a history of bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock CE; Melen E; Linden A; Wheelock AM; Skold CM
Conference publication: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2018;75(Suppl 2):a435-a436
1098 A population based longitudinal study of risk for chronic obstructive pulmonary disease and occupational exposure to organic and inorganic dust
Grahn K; Gustavsson P; Andersson T; Lindén A; Hemmingsson T; Wiebert P
Review: EUROPEAN RESPIRATORY REVIEW. 2018;27(147):170122
Cadmium in tobacco smokers: a neglected link to lung disease?
Ganguly K; Levanen B; Palmberg L; Akesson A; Linden A
Preprint: BIORXIV. 2018
The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation
Ezzat K; Pernemalm M; Pålsson S; Roberts T; Järver P; Dondalska A; Bestas B; Sobkowiak M; Levänen B; Sköld M; Thompson E; Saher O; Kari O; Lajunen T; Ekström ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power U; Masich S; Lindén A; Sandberg J; Lehtiö J; Spetz A-L; Andaloussi SEL
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:757
Interleukin 8 (IL-8), but not GRO-a, associates with carotid intima-media thickness. Results from the IMPROVE study
Velasquez IM; Malarstig A; Baldassarre D; Silveira A; Veglia F; Leander K; Tremoli E; Humphries S; Linden A; Hamsten A; De Faire U; Strawbridge RJ; Gigante B
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2017;50:pa3554
Endotoxin exposure increases LL-37, but not calprotectin, in healthy human airways
Smith M; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Conference publication: 2017;:pa990
Endotoxin-induced release of the Th17-associated cytokine interleukin (IL)-26 in human neutrophils
Che K; Linden A
Conference publication: 2017;:oa4846
Late Breaking Abstract - IL-36 receptor agonists contribute to a pro-inflammatory milieu in smokers with and without COPD
Kovach M; Levanen B; Andersson A; Asgeirsdottir H; Prada M; Linden S; Qvarfordt I; Standiford T; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Impact Of Tobacco Smoking On Extracellular Il-17a Protein In The Peripheral Airways
Levanen B; Glader P; Dahlen B; Billing B; Palmberg L; Qvarfordt I; Larsson K; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Cadmium In The Peripheral Airways Of Tobacco Smokers With And Without COPD
Levanen B; Sundblad B-M; Ji J; Midander K; Julander A; Che KF; Larsson K; Palmberg L; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Modulation Of Tlr3-Stimulated Release Of Il-26 By Il-17a And Il-22 In Bronchial Epithelial Cells
Che KF; Palmberg L; Linden A
Review: JOURNAL OF INNATE IMMUNITY. 2016;8(1):15-22
Interleukin-26: An Emerging Player in Host Defense and Inflammation
Tengvall S; Che KF; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5110
LSC Abstract - Interleukin-26 in antibacterial host defense of human lungs: Effects on neutrophil mobilization
Che KF; Tengvall S; Levanen B; Silverpil E; Smith M; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5102
Tobacco smoke causes release of IL-16 protein from NK cells in vitro
Andersson A; Malmhall C; Linden A; Bossios A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa873
Hypoxia associated with increased systemic concentrations of MPO and NE during exacerbations of COPD
Andelid K; Glader P; Yoshihara S; Andersson A; Ekberg-Jansson A; Linden A
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(2):AB180
Systemic IL-17 Signaling Relates to Gender, Disease Severity and Use of Oral Steroids in Children with Asthma
Alavi MM; Nordlund B; Thunberg S; Gronlund H; Lundahl J; Hedlin G; Linden A; Konradsen J
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2015;191
Signaling Mechanisms And Release Of Il-26 In Human Structural Lung Cells In Response To Pathogen Associated Molecular Patterns
Che KF; Ji J; Palmberg L; Skold M; Linden A
Book chapter: IL-17, IL-22 AND THEIR PRODUCING CELLS: ROLE IN INFLAMMATION AND AUTOIMMUNITY: PROGRESS IN INFLAMMATION RESEARCH. 2013;p. 259-272
Involvement of Interleukin-17 Cytokines in Human Asthma
Lindén A
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2012;6(2):173-186
IL-17 in human asthma
Silverpil E; Linden A
Letter: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2011;30(1):113
Phenotyping BOS could improve understanding of mechanisms involved Reply
Riise GC; Linden A
Editorial comment: CLINICAL RESPIRATORY JOURNAL. 2010;4:iii
Preface
Linden A; Larsson K
Conference publication: 2010;:a3825
Circulating Myeloperoxidase During COPD Exacerbations
Andelid K; Glader P; Ekberg-Jansson A; Lindén A
Conference publication: 2010;:a3490
Decreased Interleukin-17A In The Airways Of Patients With Lung Cancer?
Lärstad M; Andersson A; Riise G; Lindén A
Conference publication: 2010;:a5084
IL-17 Involved In The Immune Response To Endotoxin In Human Airways
Glader P; Smith M; Malmhäll C; Sjöstrand M; Qvarfordt I; Lindén A
Conference publication: 2010;:a1290
Macrophages Sources Of IL-22 Protein In Mouse Lungs Exposed To Peptidoglycan Or IL-23
Hansson M; Silverpil E; Glader P; Lindén A
Book chapter: NEW DRUGS AND TARGETS FOR ASTHMA AND COPD: PROGRESS IN RESPIRATORY RESEARCH. 2010;p. 141-149
Targeting interleukin-17 in the lungs
Ivanov S; Lindén A
Review: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS. 2009;9(2):178-186
Impact of IL-17 on cells of the monocyte lineage in health and disease.
Sergejeva S; Lindén A
Conference publication: JOURNAL OF IMMUNOLOGY. 2009;182:47.14
Increased number of systemic T regulatory cells but not Th1 or Th2 cells in tobacco smokers
Malmhall CA; Andersson A; Jackute J; Houltz B; Lotvall J; Linden A; Bossios A
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2009;30(2):95-103
Interleukin-17 as a drug target in human disease
Ivanov S; Linden A
Book chapter: TH 17 CELLS: ROLE IN INFLAMMATION AND AUTOIMMUNE DISEASE: PROGRESS IN INFLAMMATION RESEARCH. 2009;p. 201-209
IL-17 cytokines in asthma
Lindén A
Review: RECENT PATENTS ON INFLAMMATION AND ALLERGY DRUG DISCOVERY. 2008;2(2):82-91
The IL-17 Family of Cytokines - Applications in Respiratory Medicine and Allergology
Laan M; Linden A
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2007;2007(398):re4
A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling.
Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2005;25(1):159-172
Neutrophils, interleukin-17A and lung disease
Lindén A; Laan M; Anderson GP
Published conference paper: REGULATORY PEPTIDES. 2004;123(1-3):161-165
Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi
Yoshihara S; Yamada Y; Abe T; Kashimoto K; Lindén A; Arisaka O
Review: IMMUNITY. 2004;21(4):467-476
Interleukin-17 family members and inflammation
Kolls JK; Lindén A
Review: CURRENT OPINION IN INVESTIGATIONAL DRUGS. 2003;4(11):1304-1312
Rationale for targeting interleukin-17 in the lungs.
Lindén A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2003;22:42S
De novo synthesis of IL-17 in human airways following exposure to organic dust
Ivanov S; Prause O; Palmberg L; Larsson K; Lindén A
Review: CURRENT PHARMACEUTICAL DESIGN. 2002;8(20):1855-1861
IL-17 as a potential target for modulating airway neutrophilia
Laan M; Lindén A
Review: ALLERGY. 2002;57(9):769-775
Neutrophilic airway inflammation and IL-17
Lindén A; Adachi M
Review: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2001;126(3):179-184
Role of interleukin-17 and the neutrophil in asthma
Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2000;15(5):973-977
Airway neutrophils and interleukin-17
Lindén A; Hoshino H; Laan M
Review: EUROPEAN RESPIRATORY JOURNAL. 1999;14(2):439-442
Bronchodilation by pituitary adenylate cyclase-activating peptide and related peptides
Lindén A; Cardell LO; Yoshihara S; Nadel JA
Review: PULMONARY PHARMACOLOGY & THERAPEUTICS. 1999;12(4):229-236
PACAPs -: Potential for bronchodilation
Lindén A
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1996;805:536-542
A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea
Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Review: GENERAL PHARMACOLOGY: THE VASCULAR SYSTEM. 1996;27(7):1109-1121
NANC neural control of airway smooth muscle tone
Linden A
Review: LUNG. 1996;174(1):1-22
Pharmacological basis for duration of effect: Formoterol and salmeterol versus short-acting beta(2)-adrenoceptor agonists
Linden A; Rabe KF; Lofdahl CG
Conference publication: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1993;72:28-29
THE NANC SYSTEM AS A STABILIZER OF AIRWAY SMOOTH-MUSCLE TONE
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
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