Anders Lindén

About me
Publications
Public outreach and news

About me

Anders Lindén is a Professor of Lung and Airway Research at the Institute of Environmental Medicine (IMM). His main area of research is deficiencies in the local immune system of the lungs of smokers with and without chronic obstructive pulmonary disease (COPD). The research also concerns severe/chronic asthma, a disease that has some similarities to COPD.

Articles

Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;156(1):118-128
Nasal production of IL-26 involving T cells in smokers with and without chronic obstructive pulmonary disease
Arebro J; Pournaras N; Ramos-Ramirez P; Cardenas EI; Bandeira E; Che KF; Brundin B; Bossios A; Karimi R; Nyren S; Stjarne P; Skold M; Linden A
Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(22):4095-4104
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak MJ; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas EI; Villa V; Ricciarelli R; Sandberg JK; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay AJ; Pernemalm M; Lindeen A; Klingstrom J; El Andaloussi S; Ezzat K
Article: RESPIRATORY RESEARCH. 2024;25(1):163
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Kaeck U; Che KF; Brundin B; Konradsen JR; Linden A
Article: RESPIRATORY RESEARCH. 2024;25(1):86
Large airway T cells in adults with former bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Kaarteenaho R; Reinke NS; Wheelock CE; Melen E; Anders L; Wheelock AM; Rassidakis G; Ortiz-Villalon C; Skold MC
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1434186
Systemic increase in IL-26 is associated with severe COVID-19 and comorbid obstructive lung disease
Cardenas EI; Robertson J; Misaghian S; Brown J; Wang M; Stengelin M; Sigal G; Wohlstadter J; Gisslen M; Linden A
Article: GLYCOBIOLOGY. 2023;33(12):1128-1138
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD
Venkatakrishnan V; Thomsson KA; Padra M; Andersson A; Brundin B; Christenson K; Bylund J; Karlsson NG; Linden A; Linden SK
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2023;10(1):2181291
Comorbid conditions as predictors of mortality in severe COPD - an eight-year follow-up cohort study
Eliasson G; Janson C; Johansson G; Larsson K; Linden A; Loefdahl C-G; Sandstroem T; Sundh J
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis
Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1178135
TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26
Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;60(3):2102531
Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
Um-Bergstrom P; Pourbazargan M; Brundin B; Strom M; Ezerskyte M; Gao J; Brostrom EB; Melen E; Wheelock AM; Linden A; Skold CM
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:1179-1194
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
Pournaras N; Andersson A; Kovach MA; Padra M; Che KF; Brundin B; Yoshihara S; Bozinovski S; Linden SK; Jansson P-A; Skold MC; Qvarfordt I; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:993-1004
Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)
Lundh L; Larsson K; Linden A; Montgomery S; Palmberg L; Sandelowsky H
Article: RESPIRATORY RESEARCH. 2022;23(1):108
Involvement of IL-26 in bronchiolitis obliterans syndrome but not in acute rejection after lung transplantation
Magnusson JM; Ericson P; Tengvall S; Stockfelt M; Brundin B; Linden A; Riise GC
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2022;16(3):293-301
IL-26 in asthma and COPD
Cardenas EI; Che KF; Konradsen JR; Bao A; Linden A
Article: LAKARTIDNINGEN. 2022;119:21155
[Pharmacological treatment reduces mortality in COPD].
Larsson K; Lindberg A; Sandelowsky H; Lindén A; Ställberg B; Janson C
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1016991
Increased IL-26 associates with markers of hyperinflammation and tissue damage in patients with acute COVID-19
Cardenas EI; Ekstedt S; Piersiala K; Petro M; Karlsson A; Kagedal A; Georen SK; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;65(6):593-602
Mucin Binding to Moraxella catarrhalis during Airway Inflammation Is Dependent on Sialic Acid
Padra M; Benktander J; Padra JT; Andersson A; Brundin B; Tengvall S; Christenson K; Qvarfordt I; Gad R; Paulsson M; Pournaras N; Linden A; Linden SK
Article: ENVIRONMENTAL RESEARCH. 2021;200:111739
Occupational exposure to particles and increased risk of developing chronic obstructive pulmonary disease (COPD): A population-based cohort study in Stockholm, Sweden
Grahn K; Gustavsson P; Andersson T; Linden A; Hemmingsson T; Selander J; Wiebert P
Article: RESPIRATORY RESEARCH. 2021;22(1):174
Heparin-binding protein in lower airway samples as a biomarker for pneumonia
Paulsson M; Thelaus L; Riesbeck K; Qvarfordt I; Smith ME; Linden A; Linder A
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2021;41(2):181-191
The ratio FEV₁/FVC and its association to respiratory symptoms-A Swedish general population study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall JE; Eriksson MJ; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Lennart Persson H; Sandelin M; Eriksson Strom J; Tanash H; Vikgren J; Johan Ostgren C; Wollmer P; Skold CM
Article: EUROPEAN RESPIRATORY JOURNAL. 2021;57(3):2002120
Assessment of chronic bronchitis and risk factors in young adults: results from BAMSE.
Wang G; Hallberg J; Um Bergström P; Janson C; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Bergström A; Kull I; Lindén A; Melén E
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2021;16:367-377
Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations
Sundqvist M; Andelid K; Ekberg-Jansson A; Bylund J; Karlsson-Bengtsson A; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;64(2):173-182
IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers
Kovach MA; Che K; Brundin B; Andersson A; Asgeirsdottir H; Padra M; Linden SK; Qvarfordt I; Newstead MW; Standiford TJ; Linden A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:761317
Complex Involvement of Interleukin-26 in Bacterial Lung Infection
Che KF; Paulsson M; Piersiala K; Sax J; Mboob I; Rahman M; Rekha RS; Safholm J; Adner M; Bergman P; Cardell L-O; Riesbeck K; Linden A
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S2)
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Malm T; Gustafsson O; Lindén A; Andaloussi SEL
Article: LAKARTIDNINGEN. 2020;117:20051
[The role of inhaled steroids in the treatment of COPD].
Ställberg B; Janson C; Lindén A; Lisspers K; Larsson K
Article: BMJ OPEN RESPIRATORY RESEARCH. 2020;7(1):e000600
Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Persson HL; Sandelin M; Strom JE; Tanash HA; Vikgren J; Ostgren CJ; Wollmer P; Skold CM
Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(5):1869-1879
Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Szmidt MK; Kaluza J; Harris HR; Linden A; Wolk A
Article: CLINICAL SCIENCE. 2020;134(10):1107-1125
Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers
Padra M; Andersson A; Levanen B; Premaratne P; Asgeirsdottir H; Tengvall S; Christenson K; Stockfelt M; Bozinovski S; Yoshihara S; Lantz A-S; Palmberg L; Dahlen B; Larsson K; Qvarfordt I; Linden SK; Linden A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Journal article: REVUE DES MALADIES RESPIRATOIRES ACTUALITES. 2020;12(1):96
Aucune augmentation d’interleukin-4 et de protéine cationique des éosinophiles (ECP) dans le plasme durant des exacerbations BPCO
Andersson A; Andelid K; Levänen B; Lindén A
Article: FRONTIERS IN NEUROSCIENCE. 2020;14:256
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Sturchio A; Graff C; Espay AJ; Wright AP; El Andaloussi S; Linden A; Ezzat K
Article: JOURNAL OF INNATE IMMUNITY. 2020;12(6):480-489
Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD
Stockfelt M; Christenson K; Andersson A; Bjorkman L; Padra M; Brundin B; Ganguly K; Asgeirsdottir H; Linden S; Qvarfordt I; Bylund J; Linden A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):1134-1136.e10
Enhanced local production of IL-26 in uncontrolled compared with controlled adult asthma
Tufvesson E; Jogdand P; Che KF; Levanen B; Erjefalt JS; Bjermer L; Linden A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:956
Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
Che KF; Sun J; Linden A
Article: NATURE COMMUNICATIONS. 2019;10(1):2331
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Pernemalm M; Palsson S; Roberts TC; Jarver P; Dondalska A; Bestas B; Sobkowiak MJ; Levanen B; Skold M; Thompson EA; Saher O; Kari OK; Lajunen T; Ekstrom ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power UF; Masich S; Linden A; Sandberg JK; Lehtio J; Spetz A-L; EL Andaloussi S
Article: RESPIRATORY RESEARCH. 2019;20(1):102
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(5):907-916
Alcohol Consumption and Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Harris HR; Linden A; Wolk A
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(2):665-672
Long-term unprocessed and processed red meat consumption and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris H; Linden A; Wolk A
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(6):1897-1909
Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris HR; Linden A; Wolk A
Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy563.p3645
P3645Interleukin 8 (IL-8), but not GRO-a, associates with carotid intima-media thickness. Results from the IMPROVE study
Velasquez IM; Malarstig A; Baldassarre D; Silveira A; Veglia F; Leander K; Tremoli E; Humphries S; Linden A; Hamsten A; De Faire U; Strawbridge RJ; Gigante B; IMPROVE
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:1559
Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing
Paulsson M; Che KF; Ahi J; Tham J; Sandblad L; Smith ME; Qvarfordt I; Su Y-C; Linden A; Riesbeck K
Article: CLINICAL SCIENCE. 2018;132(9):959-983
The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers
Che KF; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold CM; Linden A
Article: EPIDEMIOLOGY. 2018;29(2):254-260
Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease A Prospective Cohort Study of Men
Kaluza J; Harris H; Wallin A; Linden A; Wolk A
Article: PLOS ONE. 2017;12(12):e0188909
Recombinant human IL-26 facilitates the innate immune response to endotoxin in the bronchoalveolar space of mice in vivo
Bao A; Che KF; Bozinovski S; Ji J; Gregory JA; Georen SK; Adner M; Cardell L-O; Linden A
Article: MOLECULAR MEDICINE. 2017;23:247-257
Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: THORAX. 2017;72(6):500-509
Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men
Kaluza J; Larsson SC; Orsini N; Linden A; Wolk A
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2017;4(1):1270079
Characterization of secondary care for COPD in Sweden
Sundh J; Janson C; Johansson G; Linden A; Lofdahl C-G; Sandstrom T; Larsson K
Journal article: REVUE DES MALADIES RESPIRATOIRES. 2017;34:a162
Le taux des éosinophiles du sang périphérique est baissé pendant des exacerbations de BPCO
Andersson A; Andelid K; Lindén A
Article: JOURNAL OF INNATE IMMUNITY. 2017;9(5):475-482
Endotoxin Exposure Increases LL-37-but Not Calprotectin - in Healthy Human Airways
Smith ME; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2016;184(11):829-836
Consumption of Unprocessed and Processed Red Meat and the Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Larsson SC; Linden A; Wolk A
Journal article: CIRCULATION. 2016;134(suppl_1)
Abstract 13512: Chemokines and Carotid Intima-Media Thickness in a European Population at High Risk for Cardiovascular Events: Results From the IMPROVE Study
Moreno Velasquez I; Malarstig A; Strawbridge RJ; Baldassarre D; Veglia F; Leander K; Silveira A; Rauramaa R; Smit AJ; Giral P; Mannarino E; Tremoli E; Humphries SE; Lindén A; Hamsten A; de Faire U; Gigante B
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2245-2258
Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
Andersson A; Malmhall C; Houltz B; Tengvall S; Sjostrand M; Qvarfordt I; Linden A; Bossios A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2109-2116
Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways
Levanen B; Glader P; Dahlen B; Billing B; Qvarfordt I; Palmberg L; Larsson K; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1005-1013
Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
Sundblad B-M; Ji J; Levanen B; Midander K; Julander A; Larsson K; Palmberg L; Linden A
Article: RESPIRATORY RESEARCH. 2016;17:32
The cytokine interleukin-26 as a biomarker in pediatric asthma
Konradsen JR; Nordlund B; Levanen B; Hedlin G; Linden A
Article: PLOS ONE. 2016;11(10):e0164751
Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function
Ostadkarampour M; Muller M; Ockinger J; Kullberg S; Linden A; Eklund A; Grunewald J; Wahlstrom J
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:2327-2334
The phenotype of concurrent chronic bronchitis and frequent exacerbations in patients with severe COPD attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Sandstrom T; Janson C
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:1253-1263
Systemic signs of neutrophil mobilization during clinically stable periods and during exacerbations in smokers with obstructive pulmonary disease
Andelid K; Andersson A; Yoshihara S; Ahren C; Jirholt P; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:689-702
Systemic cytokine signaling via IL-17 in smokers with obstructive pulmonary disease: a link to bacterial colonization?
Andelid K; Tengvall S; Andersson A; Levanen B; Christenson K; Jirholt P; Ahren C; Qvarfordt I; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:173-183
Comorbidity and health-related quality of life in patients with severe chronic obstructive pulmonary disease attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Janson C; Sandstrom T
Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(5):1319-1331
Interleukin-17 cytokine signalling in patients with asthma
Linden A; Danlen B
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;190(9):1022-1031
Interleukin-26 in Antibacterial Host Defense of Human Lungs Effects on Neutrophil Mobilization
Che KF; Tengvall S; Levanen B; Silverpil E; Smith ME; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;178(2):342-352
Higher levels of interleukin IL-17 and antigen-specific IL-17 responses in pulmonary sarcoidosis patients with Lofgren's syndrome
Ostadkarampour M; Eklund A; Moller D; Glader P; Hoglund CO; Linden A; Grunewald J; Wahlstrom J
Journal article: RESPIRATORY MEDICINE. 2013;107(11):s4
Systemic myeloperoxidase in COPD
Andelid K; Glader P; Jirholt P; Gjertsson I; Jansson AE; Lindén A
Article: INNATE IMMUNITY. 2013;19(5):479-492
Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation
Silverpil E; Wright AKA; Hansson M; Jirholt P; Henningsson L; Smith ME; Gordon SB; Iwakura Y; Gjertsson I; Glader P; Linden A
Article: INFLAMMATION RESEARCH. 2013;62(6):561-569
Interleukin-22 produced by alveolar macrophages during activation of the innate immune response
Hansson M; Silverpil E; Linden A; Glader P
Article: PLOS ONE. 2013;8(9):e75032
Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects
Smith ME; Bozinovski S; Malmhall C; Sjostrand M; Glader P; Venge P; Hiemstra PS; Anderson GP; Linden A; Qvarfordt I
Journal article: PNEUMOLOGIE. 2012;66(11)
IL-17 and antigen-specific IL-17 responses in distinct subsets of patients with pulmonary sarcoidosis
Ostadkarampour M; Eklund A; Moller D; Glader P; Lindén A; Grunewald J; Wahlström J
Article: LAKARTIDNINGEN. 2011;108(35):1604-1605
[How the care of COPD will be better].
Larsson K; Löfdahl C-G; Lindén A; Sandström T; Johansson GS
Article: INNATE IMMUNITY. 2011;17(2):204-211
¹H and hyperpolarized ³He magnetic resonance imaging clearly detect the preventative effect of a glucocorticoid on endotoxin-induced pulmonary inflammation in vivo
Olsson LE; Smailagic A; Onnervik P-O; Linden A; Hockings PD
Article: INFLAMMATION. 2011;34(1):1-9
Impact of Interleukin-17 on Macrophage Phagocytosis of Apoptotic Neutrophils and Particles
Silverpil E; Glader P; Hansson M; Linden A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2011;300(1):L43-L55
Effects of tobacco smoke on IL-16 in CD8⁺ cells from human airways and blood: a key role for oxygen free radicals?
Andersson A; Bossios A; Malmhall C; Sjostrand M; Eldh M; Eldh B-M; Glader P; Andersson B; Qvarfordt I; Riise GC; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2011;6:83-88
A gender difference in circulating neutrophils in malnourished patients with COPD
Larsson S; Nordenson A; Glader P; Yoshihara S; Linden A; Slinde F
Article: EUROPEAN RESPIRATORY JOURNAL. 2010;36(5):1155-1164
Interleukin-17-producing T-helper cells and related cytokines in human airways exposed to endotoxin
Glader P; Smith ME; Malmhall C; Balder B; Sjostrand M; Qvarfordt I; Linden A
Article: INFECTION AND IMMUNITY. 2010;78(9):3783-3790
Interleukin-17A during Local and Systemic Staphylococcus aureus-Induced Arthritis in Mice
Henningsson L; Jirholt P; Lindholm C; Eneljung T; Silverpil E; Iwakura Y; Linden A; Gjertsson I
Article: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010;29(7):800-807
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome
Riise GC; Ericson P; Bozinovski S; Yoshihara S; Anderson GP; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;182(1):34-40
Neutralizing Granulocyte/Macrophage Colony-Stimulating Factor Inhibits Cigarette Smoke-induced Lung Inflammation
Vlahos R; Bozinovski S; Chan SPJ; Ivanov S; Linden A; Hamilton JA; Anderson GP
Article: RESPIRATORY RESEARCH. 2009;10(1):94
West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma
Lotvall J; Ekerljung L; Ronmark EP; Wennergren G; Linden A; Ronmark E; Toren K; Lundback B
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2009;22(3):199-207
IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy
Prause O; Bossios A; Silverpil E; Ivanov S; Bozinovski S; Vlahos R; Sjostrand M; Anderson GP; Linden A
Journal article: JOURNAL OF IMMUNOLOGY. 2009;182(1_Supplement):134.32
IL-17-induced apoptosis correlates positively with the release of myeloperoxidase in isolated neutrophils from mice (134.32)
Silverpil E; Glader P; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(3):644-650
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
Glader P; Eldh B; Bozinovski S; Andelid K; Sjostrand M; Malmhall C; Anderson GP; Riise GC; Qvarfordt I; Linden A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(5):480-488
Prolonged eosinophil production after allergen exposure in IFN-γR KO mice is IL-5 dependent
Zhao L-L; Lotvall J; Linden A; Tomaki M; Sjostrand M; Bossios A
Journal article: RESPIRATORY MEDICINE: COPD UPDATE. 2007;3(4):123
Impact of tobacco smoke on Interleukin-16 protein in human airways and lymphocytes
Andersson A; Sjöstrand M; Qvarfordt I; Riise G; Laan M; Malmhäll C; Lindén A
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2007;1(2):279-293
Th-17 cells in the lungs?
Ivanov S; Lindén A
Article: RESPIRATORY MEDICINE. 2007;101(5):888-895
Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms
Andelid K; Bake B; Rak S; Linden A; Rosengren A; Ekberg-Jansson A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2007;36(4):442-451
Functional relevance of the IL-23-IL-17 axis in lungs in vivo
Ivanov S; Bozinovski S; Bossios A; Valadi H; Vlahos R; Malmhall C; Sjostrand M; Kolls JK; Anderson GP; Linden A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2006;144(2):212-216
Association of epithelial damage and signs of neutrophil mobilization in the airways during acute exacerbations of paediatric asthma
Yoshihara S; Yamada Y; Abe T; Lindén A; Arisaka O
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2006;19(1):47-50
Interleukin-17 and airway remodelling
Lindén A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2005;33(3):248-253
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation
Sergejeva S; Ivanov S; Lötvall J; Lindén A
Article: RESPIRATORY RESEARCH. 2005;6(1):44
Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust - art. no. 44
Ivanov S; Palmberg L; Venge P; Larsson K; Lindén A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;138(1):75-82
Impact of tobacco smoke on interleukin-16 protein in human airways, lymphoid tissue and T lymphocytes
Andersson A; Qvarfordt I; Laan M; Sjöstrand M; Malmhäll C; Riise GC; Cardell LO; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2004;24(2):231-237
β-adrenoceptor stimulation and neutrophil accumulation in mouse airways
Miyamoto M; Tomaki M; Lötvall J; Lindén A
Article: THORAX. 2004;59(4):313-317
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
Prause O; Bozinovski S; Anderson GP; Lindén A
Article: REGULATORY PEPTIDES. 2004;117(2):149-154
A synthetic VIP peptide analogue inhibits neutrophil recruitment in rat airways in vivo
Sergejeva S; Hoshino H; Yoshihara S; Kashimoto K; Lötvall J; Lindén A
Article: RESPIRATORY MEDICINE. 2004;98(2):159-163
BAL levels of interleukin-18 do not change before or during acute rejection in lungtransplant recipients
Ericson P; Lindén A; Riise GC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;133(2):290-296
IL-16 in the airways of lung allograft recipients with acute rejection or obliterative bronchiolitis
Laan M; Lindén A; Riise GC
Article: JOURNAL OF IMMUNOLOGY. 2003;170(9):4665-4672
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways
Miyamoto M; Prause O; Sjöstrand M; Laan M; Lötvall J; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;21(3):387-393
A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF-α
Laan M; Prause O; Miyamoto M; Sjöstrand M; Hytönen AM; Kaneko T; Löotvall J; Lindén A
Article: THORAX. 2003;58(3):217-221
Bronchodilation by an inhaled VPAC₂ receptor agonist in patients with stable asthma
Lindén A; Hansson L; Andersson A; Palmqvist M; Arvidsson P; Löfdahl CG; Larsson P; Lötvall J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;462(1-3):193-198
Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells
Prause O; Laan M; Lötvall J; Lindén A
Journal article: ALLERGOLOGY INTERNATIONAL. 2003;52(4):173-182
Neutrophils, interleukin-17 and obstructive airway disease
Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(3):534-537
Free, soluble interleukin-17 protein during severe inflammation in human airways
Laan M; Palmberg L; Larsson K; Lindén A
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2002;15(2):161-168
Comparison of effects of Anti-IL-3, IL-5 and GM-CSF treatments on eosinophilopoiesis and airway eosinophilia induced by allergen
Tomaki M; Zhao LL; Sjöstrand M; Lindén A; Ichinose M; Lötvall J
Article: PEPTIDES. 2001;22(12):2151-2154
Pituitary adenylate cyclase-activating peptide inhibits neutrophil chemotaxis
Kinhult J; Uddman R; Laan M; Lindén A; Cardell LO
Article: ALLERGY. 2001;56(9):871-877
Effect of seasonal allergen exposure on mucosal IL-16 and CD4+cells in patients with allergic rhinitis
Pullerits T; Lindén A; Malmhäll C; Lötvall J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2001;133(1):200-206
IL-17-induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen-activated protein (MAP) kinases
Laan M; Lötvall J; Chung KF; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2001;17(5):872-880
Reduced late asthmatic response by repeated low-dose allergen exposure
Palmqvist M; Cui ZH; Sjöstrand M; Lindén A; Lötvall J
Article: JOURNAL OF IMMUNOLOGY. 2000;165(7):4040-4050
Eosinophilopoiesis in a murine model of allergic airway eosinophilia: Involvement of bone marrow IL-5 and IL-5 receptor α
Tomaki M; Zhao LL; Lundahl J; Sjöstrand M; Jordana M; Lindén A; O'Byrne P; Lötvall J
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1469-1475
Upregulation of nasal mucosal eotaxin in patients with allergic rhinitis during grass pollen season:: effect of a local glucocorticoid
Pullerits T; Lindén A; Praks L; Cardell LO; Lötvall J
Article: ALLERGY. 2000;55(8):749-756
IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure
Zhao LL; Lindén A; Sjöstrand M; Cui ZH; Lötvall J; Jordana M
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s294
863 Attenuation of early phase airway response and plasma exudation due to reduction of leukotrines production after repeated allergen exposure
Cui Z-H; Pullerits T; Linden A; Skoogh B-E; Lotvall J
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):143-149
Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo
Hoshino H; Laan M; Sjöstrand M; Lötvall J; Skoogh BE; Lindén A
Article: THORAX. 1999;54(10):911-916
Increased levels of interleukin-16 in the airways of tobacco smokers: relationship with peripheral blood T lymphocytes
Laan M; Qvarfordt I; Riise GC; Andersson BA; Larsson S; Lindén A
Article: REGULATORY PEPTIDES. 1999;81(1-3):49-53
Effect of nedocromil sodium on non-adrenergic, non-cholinergic neural responses in guinea pig bronchi in vitro
Lindén A; Bergendal A; Lötvall J; Skoogh BE; Löfdahl CG
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;159(5):1423-1428
Neutrophil recruitment by interleukin-17 into rat airways in vivo - Role of tachykinins
Hoshino H; Lötvall J; Skoogh BE; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 1999;162(4):2347-2352
Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
Laan M; Cui ZH; Hoshino H; Lötvall J; Sjöstrand M; Gruenert DC; Skoogh BE; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(5):1062-1066
Effect of a novel PACAP-27 analogue on muscarinic airway responsiveness in guinea-pigs in vivo
Okazawa A; Cui ZH; Lotvall J; Yoshihara S; Skoogh BE; Kashimoto K; Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1998;124(6):1065-1068
Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger
Cardell LO; Ueki IF; Stjärne P; Agusti C; Takeyama K; Lindén A; Nadel JA
Article: BIOMEDICAL RESEARCH-TOKYO. 1998;19(1):39-44
Sustained relaxant action of [Arg^15,20,21, Leu¹⁷]-PACAP-27-NH₂ on carbachol-induced contraction of guinea-pig tracheal smooth muscle in vitro
Yamada Y; Yoshihara S; Kashimoto K; Linden A; Ichimura T
Article: PEPTIDES. 1998;19(3):593-597
A novel long-acting VIP analog in the guinea pig trachea in vitro
Yoshihara S; Lindén A; Kashimoto K; Watanabe S
Article: PEPTIDES. 1998;19(1):93-98
PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo
Lindén A; Cardell LO; Yoshihara S; Stjärne P; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(8):1730-1734
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro
Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Article: PEPTIDES. 1997;18(6):843-846
Functional type II VIP-PACAP receptors in human airway epithelial-like cells
Linden A; Yoshihara S; Cardell LO; Kaneko T; Stjarne P; Nadel JA
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(5):L838-L843
Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways
Massion PP; Linden A; Inoue H; Mathy M; Grattan KM; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;119(2):402-406
Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells
Linden A
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;97(3):756-760
Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs
Yoshihara S; Geppetti P; Lindan A; Hara M; Chan BD; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;117(6):1009-1015
Extent of salmeterol-mediated reassertion of relaxation in guineapig trachea pretreated with aliphatic side chain structural analogues
Bergendal A; Linden A; Skoogh BE; Gerspacher M; Anderson GP; Lofdahl CG
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;296(3):291-296
Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs
Yoshihara S; Geppetti P; Hara M; Linden A; Ricciardolo FLM; Chan B; Nadel JA
Article: LUNG. 1996;174(3):159-170
Relaxation kinetics of formoterol and salmeterol in the guinea pig trachea in vitro
Anderson P; Lotvall J; Linden A
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;280(2):113-118
CORTICOTROPIN-RELEASING FACTOR INHIBITS ANTIGEN-INDUCED PLASMA EXTRAVASATION IN AIRWAYS
YOSHIHARA S; RICCIARDOLO FLM; GEPPETTI P; LINDEN A; HARA M; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;115(6):913-916
INHIBITION OF BRONCHOCONSTRICTION BY PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP-1-27) IN GUINEA-PIGS IN-VIVO
LINDEN A; YOSHIHARA S; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;114(7):1478-1482
DIFFERENT EFFECTS OF SALMETEROL, FORMOTEROL AND SALBUTAMOL ON CHOLINERGIC RESPONSES IN THE FERRET TRACHEA
BERGENDAL A; LINDEN A; LOTVALL J; SKOOGH BE; LOFDAHL CG
Journal article: CLINICAL AND EXPERIMENTAL ALLERGY. 1994;24(6):582-589
ROLE OF EICOSANOIDS IN AIR-FLOW OBSTRUCTION AND AIRWAY PLASMA EXUDATION INDUCED BY TRIMELLITIC ANHYDRIDE-CONJUGATE IN GUINEA-PIGS 3 AND 8 WEEKS AFTER SENSITIZATION
ARAKAWA H; LOTVALL J; LINDEN A; KAWIKOVA I; LOFDAHL CG; SKOOGH BE
Journal article: RESPIRATORY MEDICINE. 1994;88(4):249-265
NANC RESPONSES - ROLE IN CONTROL OF AIRWAY TONE
LINDEN A; SKOOGH BE
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1994;7(3):569-578
WHY ARE LONG-ACTING BETA-ADRENOCEPTOR AGONISTS LONG-ACTING
ANDERSON GP; LINDEN A; RABE KF
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1993;109(3):845-851
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION IN GUINEA-PIG BRONCHI - POWERFUL AND FREQUENCY-DEPENDENT STABILIZING EFFECT ON TONE
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: THORAX. 1993;48(5):547-553
SALMETEROL, FORMOTEROL, AND SALBUTAMOL IN THE ISOLATED GUINEA-PIG TRACHEA - DIFFERENCES IN MAXIMUM RELAXANT EFFECT AND POTENCY BUT NOT IN FUNCTIONAL ANTAGONISM
LINDEN A; BERGENDAL A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1993;6(3):425-433
NONADRENERGIC, NONCHOLINERGIC RESPONSES STABILIZE SMOOTH-MUSCLE TONE, WITH AND WITHOUT PARASYMPATHETIC ACTIVATION, IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: ALLERGY. 1992;47(4):384-387
ONSET OF ACTION AND DURATION OF EFFECT OF FORMOTEROL AND SALMETEROL COMPARED TO SALBUTAMOL IN ISOLATED GUINEA-PIG TRACHEA WITH OR WITHOUT EPITHELIUM
ULLMAN A; BERGENDAL A; LINDEN A; WALDECK B; SKOOGH BE; LOFDAHL CG
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1992;71(1):41-44
INVITRO TACHYPHYLAXIS TO ISOPRENALINE IN GUINEA-PIG TRACHEA - INFLUENCE OF THEOPHYLLINE
BERGENDAL A; LINDEN A; LOTVALL J; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1992;106(3):616-622
THE NONADRENERGIC, NONCHOLINERGIC RESPONSE COUNTERACTS CHANGES IN GUINEA-PIG AIRWAY TONE WITH AND WITHOUT SYMPATHETIC ACTIVATION
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1991;104(2):509-513
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION STABILIZES SMOOTH-MUSCLE TONE INDEPENDENTLY OF EICOSANOID FACTORS IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: ACTA PHYSIOLOGICA. 1991;142(3):351-357
INVITRO CHARACTERISTICS OF SPONTANEOUS AIRWAY TONE IN THE GUINEA-PIG
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: PULMONARY PHARMACOLOGY. 1991;4(3):170-176
NONADRENERGIC, NONCHOLINERGIC REGULATION OF GUINEA-PIG AIRWAY SMOOTH-MUSCLE INDOMETHACIN-INDUCED CHANGES AND SEGMENTAL DIFFERENCES
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: PULMONARY PHARMACOLOGY. 1990;3(3):155-160
Epithelium-derived PGE2 inhibits the contractile response to cholinergic stimulation in isolated ferret trachea.
Ullman A; Ciabattoni G; Löfdahl CG; Lindén A; Svedmyr N; Skoogh BE
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