Anders Lindén

About me
Publications
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About me

Anders Lindén is a Professor of Lung and Airway Research at the Institute of Environmental Medicine (IMM). His main area of research is deficiencies in the local immune system of the lungs of smokers with and without chronic obstructive pulmonary disease (COPD). The research also concerns severe/chronic asthma, a disease that has some similarities to COPD.

Articles

Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2025;156(1):118-128
Nasal production of IL-26 involving T cells in smokers with and without chronic obstructive pulmonary disease
Arebro J; Pournaras N; Ramos-Ramirez P; Cardenas EI; Bandeira E; Che KF; Brundin B; Bossios A; Karimi R; Nyren S; Stjarne P; Skold M; Linden A
Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(22):4095-4104
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak MJ; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas EI; Villa V; Ricciarelli R; Sandberg JK; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay AJ; Pernemalm M; Lindeen A; Klingstrom J; El Andaloussi S; Ezzat K
Article: RESPIRATORY RESEARCH. 2024;25(1):163
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Kaeck U; Che KF; Brundin B; Konradsen JR; Linden A
Article: RESPIRATORY RESEARCH. 2024;25(1):86
Large airway T cells in adults with former bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Kaarteenaho R; Reinke NS; Wheelock CE; Melen E; Anders L; Wheelock AM; Rassidakis G; Ortiz-Villalon C; Skold MC
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1434186
Systemic increase in IL-26 is associated with severe COVID-19 and comorbid obstructive lung disease
Cardenas EI; Robertson J; Misaghian S; Brown J; Wang M; Stengelin M; Sigal G; Wohlstadter J; Gisslen M; Linden A
Article: GLYCOBIOLOGY. 2023;33(12):1128-1138
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD
Venkatakrishnan V; Thomsson KA; Padra M; Andersson A; Brundin B; Christenson K; Bylund J; Karlsson NG; Linden A; Linden SK
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2023;10(1):2181291
Comorbid conditions as predictors of mortality in severe COPD - an eight-year follow-up cohort study
Eliasson G; Janson C; Johansson G; Larsson K; Linden A; Loefdahl C-G; Sandstroem T; Sundh J
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1178135
TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26
Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374
Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis
Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;60(3):2102531
Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia
Um-Bergstrom P; Pourbazargan M; Brundin B; Strom M; Ezerskyte M; Gao J; Brostrom EB; Melen E; Wheelock AM; Linden A; Skold CM
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:1179-1194
Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD
Pournaras N; Andersson A; Kovach MA; Padra M; Che KF; Brundin B; Yoshihara S; Bozinovski S; Linden SK; Jansson P-A; Skold MC; Qvarfordt I; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:993-1004
Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)
Lundh L; Larsson K; Linden A; Montgomery S; Palmberg L; Sandelowsky H
Article: RESPIRATORY RESEARCH. 2022;23(1):108
Involvement of IL-26 in bronchiolitis obliterans syndrome but not in acute rejection after lung transplantation
Magnusson JM; Ericson P; Tengvall S; Stockfelt M; Brundin B; Linden A; Riise GC
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2022;16(3):293-301
IL-26 in asthma and COPD
Cardenas EI; Che KF; Konradsen JR; Bao A; Linden A
Article: LAKARTIDNINGEN. 2022;119:21155
[Pharmacological treatment reduces mortality in COPD].
Larsson K; Lindberg A; Sandelowsky H; Lindén A; Ställberg B; Janson C
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1016991
Increased IL-26 associates with markers of hyperinflammation and tissue damage in patients with acute COVID-19
Cardenas EI; Ekstedt S; Piersiala K; Petro M; Karlsson A; Kagedal A; Georen SK; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;65(6):593-602
Mucin Binding to Moraxella catarrhalis during Airway Inflammation Is Dependent on Sialic Acid
Padra M; Benktander J; Padra JT; Andersson A; Brundin B; Tengvall S; Christenson K; Qvarfordt I; Gad R; Paulsson M; Pournaras N; Linden A; Linden SK
Article: ENVIRONMENTAL RESEARCH. 2021;200:111739
Occupational exposure to particles and increased risk of developing chronic obstructive pulmonary disease (COPD): A population-based cohort study in Stockholm, Sweden
Grahn K; Gustavsson P; Andersson T; Linden A; Hemmingsson T; Selander J; Wiebert P
Article: RESPIRATORY RESEARCH. 2021;22(1):174
Heparin-binding protein in lower airway samples as a biomarker for pneumonia
Paulsson M; Thelaus L; Riesbeck K; Qvarfordt I; Smith ME; Linden A; Linder A
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2021;41(2):181-191
The ratio FEV₁/FVC and its association to respiratory symptoms-A Swedish general population study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall JE; Eriksson MJ; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Lennart Persson H; Sandelin M; Eriksson Strom J; Tanash H; Vikgren J; Johan Ostgren C; Wollmer P; Skold CM
Article: EUROPEAN RESPIRATORY JOURNAL. 2021;57(3):2002120
Assessment of chronic bronchitis and risk factors in young adults: results from BAMSE.
Wang G; Hallberg J; Um Bergström P; Janson C; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Bergström A; Kull I; Lindén A; Melén E
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2021;16:367-377
Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations
Sundqvist M; Andelid K; Ekberg-Jansson A; Bylund J; Karlsson-Bengtsson A; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;64(2):173-182
IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers
Kovach MA; Che K; Brundin B; Andersson A; Asgeirsdottir H; Padra M; Linden SK; Qvarfordt I; Newstead MW; Standiford TJ; Linden A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:761317
Complex Involvement of Interleukin-26 in Bacterial Lung Infection
Che KF; Paulsson M; Piersiala K; Sax J; Mboob I; Rahman M; Rekha RS; Safholm J; Adner M; Bergman P; Cardell L-O; Riesbeck K; Linden A
Journal article: ALZHEIMERS & DEMENTIA. 2020;16(S2)
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Malm T; Gustafsson O; Lindén A; Andaloussi SEL
Article: LAKARTIDNINGEN. 2020;117:20051
[The role of inhaled steroids in the treatment of COPD].
Ställberg B; Janson C; Lindén A; Lisspers K; Larsson K
Article: BMJ OPEN RESPIRATORY RESEARCH. 2020;7(1):e000600
Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study
Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Persson HL; Sandelin M; Strom JE; Tanash HA; Vikgren J; Ostgren CJ; Wollmer P; Skold CM
Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(5):1869-1879
Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Szmidt MK; Kaluza J; Harris HR; Linden A; Wolk A
Article: CLINICAL SCIENCE. 2020;134(10):1107-1125
Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers
Padra M; Andersson A; Levanen B; Premaratne P; Asgeirsdottir H; Tengvall S; Christenson K; Stockfelt M; Bozinovski S; Yoshihara S; Lantz A-S; Palmberg L; Dahlen B; Larsson K; Qvarfordt I; Linden SK; Linden A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Journal article: REVUE DES MALADIES RESPIRATOIRES ACTUALITES. 2020;12(1):96
Aucune augmentation d’interleukin-4 et de protéine cationique des éosinophiles (ECP) dans le plasme durant des exacerbations BPCO
Andersson A; Andelid K; Levänen B; Lindén A
Article: FRONTIERS IN NEUROSCIENCE. 2020;14:256
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Sturchio A; Graff C; Espay AJ; Wright AP; El Andaloussi S; Linden A; Ezzat K
Article: JOURNAL OF INNATE IMMUNITY. 2020;12(6):480-489
Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD
Stockfelt M; Christenson K; Andersson A; Bjorkman L; Padra M; Brundin B; Ganguly K; Asgeirsdottir H; Linden S; Qvarfordt I; Bylund J; Linden A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):1134-1136.e10
Enhanced local production of IL-26 in uncontrolled compared with controlled adult asthma
Tufvesson E; Jogdand P; Che KF; Levanen B; Erjefalt JS; Bjermer L; Linden A
Article: NATURE COMMUNICATIONS. 2019;10(1):2331
The viral protein corona directs viral pathogenesis and amyloid aggregation
Ezzat K; Pernemalm M; Palsson S; Roberts TC; Jarver P; Dondalska A; Bestas B; Sobkowiak MJ; Levanen B; Skold M; Thompson EA; Saher O; Kari OK; Lajunen T; Ekstrom ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power UF; Masich S; Linden A; Sandberg JK; Lehtio J; Spetz A-L; EL Andaloussi S
Article: RESPIRATORY RESEARCH. 2019;20(1):102
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(5):907-916
Alcohol Consumption and Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Harris HR; Linden A; Wolk A
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(2):665-672
Long-term unprocessed and processed red meat consumption and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris H; Linden A; Wolk A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:956
Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts
Che KF; Sun J; Linden A
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(6):1897-1909
Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
Kaluza J; Harris HR; Linden A; Wolk A
Journal article: EUROPEAN HEART JOURNAL. 2018;39(suppl_1):ehy563.p3645
P3645Interleukin 8 (IL-8), but not GRO-a, associates with carotid intima-media thickness. Results from the IMPROVE study
Velasquez IM; Malarstig A; Baldassarre D; Silveira A; Veglia F; Leander K; Tremoli E; Humphries S; Linden A; Hamsten A; De Faire U; Strawbridge RJ; Gigante B; IMPROVE
Article: CLINICAL SCIENCE. 2018;132(9):959-983
The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers
Che KF; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold CM; Linden A
Article: EPIDEMIOLOGY. 2018;29(2):254-260
Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease A Prospective Cohort Study of Men
Kaluza J; Harris H; Wallin A; Linden A; Wolk A
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:1559
Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing
Paulsson M; Che KF; Ahi J; Tham J; Sandblad L; Smith ME; Qvarfordt I; Su Y-C; Linden A; Riesbeck K
Article: MOLECULAR MEDICINE. 2017;23:247-257
Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: THORAX. 2017;72(6):500-509
Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men
Kaluza J; Larsson SC; Orsini N; Linden A; Wolk A
Journal article: REVUE DES MALADIES RESPIRATOIRES. 2017;34:a162
Le taux des éosinophiles du sang périphérique est baissé pendant des exacerbations de BPCO
Andersson A; Andelid K; Lindén A
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2017;4(1):1270079
Characterization of secondary care for COPD in Sweden
Sundh J; Janson C; Johansson G; Linden A; Lofdahl C-G; Sandstrom T; Larsson K
Article: JOURNAL OF INNATE IMMUNITY. 2017;9(5):475-482
Endotoxin Exposure Increases LL-37-but Not Calprotectin - in Healthy Human Airways
Smith ME; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Article: PLOS ONE. 2017;12(12):e0188909
Recombinant human IL-26 facilitates the innate immune response to endotoxin in the bronchoalveolar space of mice in vivo
Bao A; Che KF; Bozinovski S; Ji J; Gregory JA; Georen SK; Adner M; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2016;184(11):829-836
Consumption of Unprocessed and Processed Red Meat and the Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men
Kaluza J; Larsson SC; Linden A; Wolk A
Journal article: CIRCULATION. 2016;134(suppl_1)
Abstract 13512: Chemokines and Carotid Intima-Media Thickness in a European Population at High Risk for Cardiovascular Events: Results From the IMPROVE Study
Moreno Velasquez I; Malarstig A; Strawbridge RJ; Baldassarre D; Veglia F; Leander K; Silveira A; Rauramaa R; Smit AJ; Giral P; Mannarino E; Tremoli E; Humphries SE; Lindén A; Hamsten A; de Faire U; Gigante B
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2245-2258
Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
Andersson A; Malmhall C; Houltz B; Tengvall S; Sjostrand M; Qvarfordt I; Linden A; Bossios A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2109-2116
Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways
Levanen B; Glader P; Dahlen B; Billing B; Qvarfordt I; Palmberg L; Larsson K; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1005-1013
Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation
Sundblad B-M; Ji J; Levanen B; Midander K; Julander A; Larsson K; Palmberg L; Linden A
Article: RESPIRATORY RESEARCH. 2016;17:32
The cytokine interleukin-26 as a biomarker in pediatric asthma
Konradsen JR; Nordlund B; Levanen B; Hedlin G; Linden A
Article: PLOS ONE. 2016;11(10):e0164751
Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function
Ostadkarampour M; Muller M; Ockinger J; Kullberg S; Linden A; Eklund A; Grunewald J; Wahlstrom J
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:2327-2334
The phenotype of concurrent chronic bronchitis and frequent exacerbations in patients with severe COPD attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Sandstrom T; Janson C
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:1253-1263
Systemic signs of neutrophil mobilization during clinically stable periods and during exacerbations in smokers with obstructive pulmonary disease
Andelid K; Andersson A; Yoshihara S; Ahren C; Jirholt P; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:689-702
Systemic cytokine signaling via IL-17 in smokers with obstructive pulmonary disease: a link to bacterial colonization?
Andelid K; Tengvall S; Andersson A; Levanen B; Christenson K; Jirholt P; Ahren C; Qvarfordt I; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:173-183
Comorbidity and health-related quality of life in patients with severe chronic obstructive pulmonary disease attending Swedish secondary care units
Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Janson C; Sandstrom T
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;190(9):1022-1031
Interleukin-26 in Antibacterial Host Defense of Human Lungs Effects on Neutrophil Mobilization
Che KF; Tengvall S; Levanen B; Silverpil E; Smith ME; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(5):1319-1331
Interleukin-17 cytokine signalling in patients with asthma
Linden A; Danlen B
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;178(2):342-352
Higher levels of interleukin IL-17 and antigen-specific IL-17 responses in pulmonary sarcoidosis patients with Lofgren's syndrome
Ostadkarampour M; Eklund A; Moller D; Glader P; Hoglund CO; Linden A; Grunewald J; Wahlstrom J
Journal article: RESPIRATORY MEDICINE. 2013;107(11):s4
Systemic myeloperoxidase in COPD
Andelid K; Glader P; Jirholt P; Gjertsson I; Jansson AE; Lindén A
Article: INNATE IMMUNITY. 2013;19(5):479-492
Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation
Silverpil E; Wright AKA; Hansson M; Jirholt P; Henningsson L; Smith ME; Gordon SB; Iwakura Y; Gjertsson I; Glader P; Linden A
Article: INFLAMMATION RESEARCH. 2013;62(6):561-569
Interleukin-22 produced by alveolar macrophages during activation of the innate immune response
Hansson M; Silverpil E; Linden A; Glader P
Article: PLOS ONE. 2013;8(9):e75032
Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects
Smith ME; Bozinovski S; Malmhall C; Sjostrand M; Glader P; Venge P; Hiemstra PS; Anderson GP; Linden A; Qvarfordt I
Journal article: PNEUMOLOGIE. 2012;66(11)
IL-17 and antigen-specific IL-17 responses in distinct subsets of patients with pulmonary sarcoidosis
Ostadkarampour M; Eklund A; Moller D; Glader P; Lindén A; Grunewald J; Wahlström J
Article: LAKARTIDNINGEN. 2011;108(35):1604-1605
[How the care of COPD will be better].
Larsson K; Löfdahl C-G; Lindén A; Sandström T; Johansson GS
Article: INNATE IMMUNITY. 2011;17(2):204-211
¹H and hyperpolarized ³He magnetic resonance imaging clearly detect the preventative effect of a glucocorticoid on endotoxin-induced pulmonary inflammation in vivo
Olsson LE; Smailagic A; Onnervik P-O; Linden A; Hockings PD
Article: INFLAMMATION. 2011;34(1):1-9
Impact of Interleukin-17 on Macrophage Phagocytosis of Apoptotic Neutrophils and Particles
Silverpil E; Glader P; Hansson M; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2011;6:83-88
A gender difference in circulating neutrophils in malnourished patients with COPD
Larsson S; Nordenson A; Glader P; Yoshihara S; Linden A; Slinde F
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2011;300(1):L43-L55
Effects of tobacco smoke on IL-16 in CD8⁺ cells from human airways and blood: a key role for oxygen free radicals?
Andersson A; Bossios A; Malmhall C; Sjostrand M; Eldh M; Eldh B-M; Glader P; Andersson B; Qvarfordt I; Riise GC; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2010;36(5):1155-1164
Interleukin-17-producing T-helper cells and related cytokines in human airways exposed to endotoxin
Glader P; Smith ME; Malmhall C; Balder B; Sjostrand M; Qvarfordt I; Linden A
Article: INFECTION AND IMMUNITY. 2010;78(9):3783-3790
Interleukin-17A during Local and Systemic Staphylococcus aureus-Induced Arthritis in Mice
Henningsson L; Jirholt P; Lindholm C; Eneljung T; Silverpil E; Iwakura Y; Linden A; Gjertsson I
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;182(1):34-40
Neutralizing Granulocyte/Macrophage Colony-Stimulating Factor Inhibits Cigarette Smoke-induced Lung Inflammation
Vlahos R; Bozinovski S; Chan SPJ; Ivanov S; Linden A; Hamilton JA; Anderson GP
Article: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010;29(7):800-807
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome
Riise GC; Ericson P; Bozinovski S; Yoshihara S; Anderson GP; Linden A
Article: RESPIRATORY RESEARCH. 2009;10(1):94
West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma
Lotvall J; Ekerljung L; Ronmark EP; Wennergren G; Linden A; Ronmark E; Toren K; Lundback B
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2009;22(3):199-207
IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy
Prause O; Bossios A; Silverpil E; Ivanov S; Bozinovski S; Vlahos R; Sjostrand M; Anderson GP; Linden A
Journal article: JOURNAL OF IMMUNOLOGY. 2009;182(1_Supplement):134.32
IL-17-induced apoptosis correlates positively with the release of myeloperoxidase in isolated neutrophils from mice (134.32)
Silverpil E; Glader P; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(3):644-650
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
Glader P; Eldh B; Bozinovski S; Andelid K; Sjostrand M; Malmhall C; Anderson GP; Riise GC; Qvarfordt I; Linden A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(5):480-488
Prolonged eosinophil production after allergen exposure in IFN-γR KO mice is IL-5 dependent
Zhao L-L; Lotvall J; Linden A; Tomaki M; Sjostrand M; Bossios A
Journal article: RESPIRATORY MEDICINE: COPD UPDATE. 2007;3(4):123
Impact of tobacco smoke on Interleukin-16 protein in human airways and lymphocytes
Andersson A; Sjöstrand M; Qvarfordt I; Riise G; Laan M; Malmhäll C; Lindén A
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2007;1(2):279-293
Th-17 cells in the lungs?
Ivanov S; Lindén A
Article: RESPIRATORY MEDICINE. 2007;101(5):888-895
Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms
Andelid K; Bake B; Rak S; Linden A; Rosengren A; Ekberg-Jansson A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2007;36(4):442-451
Functional relevance of the IL-23-IL-17 axis in lungs in vivo
Ivanov S; Bozinovski S; Bossios A; Valadi H; Vlahos R; Malmhall C; Sjostrand M; Kolls JK; Anderson GP; Linden A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2006;144(2):212-216
Association of epithelial damage and signs of neutrophil mobilization in the airways during acute exacerbations of paediatric asthma
Yoshihara S; Yamada Y; Abe T; Lindén A; Arisaka O
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2006;19(1):47-50
Interleukin-17 and airway remodelling
Lindén A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2005;33(3):248-253
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation
Sergejeva S; Ivanov S; Lötvall J; Lindén A
Article: RESPIRATORY RESEARCH. 2005;6(1):44
Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust -: art. no. 44
Ivanov S; Palmberg L; Venge P; Larsson K; Lindén A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;138(1):75-82
Impact of tobacco smoke on interleukin-16 protein in human airways, lymphoid tissue and T lymphocytes
Andersson A; Qvarfordt I; Laan M; Sjöstrand M; Malmhäll C; Riise GC; Cardell LO; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2004;24(2):231-237
β-adrenoceptor stimulation and neutrophil accumulation in mouse airways
Miyamoto M; Tomaki M; Lötvall J; Lindén A
Article: THORAX. 2004;59(4):313-317
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
Prause O; Bozinovski S; Anderson GP; Lindén A
Article: REGULATORY PEPTIDES. 2004;117(2):149-154
A synthetic VIP peptide analogue inhibits neutrophil recruitment in rat airways in vivo
Sergejeva S; Hoshino H; Yoshihara S; Kashimoto K; Lötvall J; Lindén A
Article: RESPIRATORY MEDICINE. 2004;98(2):159-163
BAL levels of interleukin-18 do not change before or during acute rejection in lungtransplant recipients
Ericson P; Lindén A; Riise GC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;133(2):290-296
IL-16 in the airways of lung allograft recipients with acute rejection or obliterative bronchiolitis
Laan M; Lindén A; Riise GC
Article: JOURNAL OF IMMUNOLOGY. 2003;170(9):4665-4672
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways
Miyamoto M; Prause O; Sjöstrand M; Laan M; Lötvall J; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;21(3):387-393
A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF-α
Laan M; Prause O; Miyamoto M; Sjöstrand M; Hytönen AM; Kaneko T; Löotvall J; Lindén A
Article: THORAX. 2003;58(3):217-221
Bronchodilation by an inhaled VPAC₂ receptor agonist in patients with stable asthma
Lindén A; Hansson L; Andersson A; Palmqvist M; Arvidsson P; Löfdahl CG; Larsson P; Lötvall J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;462(1-3):193-198
Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells
Prause O; Laan M; Lötvall J; Lindén A
Journal article: ALLERGOLOGY INTERNATIONAL. 2003;52(4):173-182
Neutrophils, interleukin-17 and obstructive airway disease
Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(3):534-537
Free, soluble interleukin-17 protein during severe inflammation in human airways
Laan M; Palmberg L; Larsson K; Lindén A
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2002;15(2):161-168
Comparison of effects of Anti-IL-3, IL-5 and GM-CSF treatments on eosinophilopoiesis and airway eosinophilia induced by allergen
Tomaki M; Zhao LL; Sjöstrand M; Lindén A; Ichinose M; Lötvall J
Article: PEPTIDES. 2001;22(12):2151-2154
Pituitary adenylate cyclase-activating peptide inhibits neutrophil chemotaxis
Kinhult J; Uddman R; Laan M; Lindén A; Cardell LO
Article: ALLERGY. 2001;56(9):871-877
Effect of seasonal allergen exposure on mucosal IL-16 and CD4+cells in patients with allergic rhinitis
Pullerits T; Lindén A; Malmhäll C; Lötvall J
Article: EUROPEAN RESPIRATORY JOURNAL. 2001;17(5):872-880
Reduced late asthmatic response by repeated low-dose allergen exposure
Palmqvist M; Cui ZH; Sjöstrand M; Lindén A; Lötvall J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2001;133(1):200-206
IL-17-induced cytokine release in human bronchial epithelial cells in vitro:: role of mitogen-activated protein (MAP) kinases
Laan M; Lötvall J; Chung KF; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 2000;165(7):4040-4050
Eosinophilopoiesis in a murine model of allergic airway eosinophilia:: Involvement of bone marrow IL-5 and IL-5 receptor α
Tomaki M; Zhao LL; Lundahl J; Sjöstrand M; Jordana M; Lindén A; O'Byrne P; Lötvall J
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1469-1475
Upregulation of nasal mucosal eotaxin in patients with allergic rhinitis during grass pollen season:: effect of a local glucocorticoid
Pullerits T; Lindén A; Praks L; Cardell LO; Lötvall J
Article: ALLERGY. 2000;55(8):749-756
IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure
Zhao LL; Lindén A; Sjöstrand M; Cui ZH; Lötvall J; Jordana M
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s294
863 Attenuation of early phase airway response and plasma exudation due to reduction of leukotrines production after repeated allergen exposure
Cui Z-H; Pullerits T; Linden A; Skoogh B-E; Lotvall J
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):143-149
Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo
Hoshino H; Laan M; Sjöstrand M; Lötvall J; Skoogh BE; Lindén A
Article: THORAX. 1999;54(10):911-916
Increased levels of interleukin-16 in the airways of tobacco smokers:: relationship with peripheral blood T lymphocytes
Laan M; Qvarfordt I; Riise GC; Andersson BA; Larsson S; Lindén A
Article: REGULATORY PEPTIDES. 1999;81(1-3):49-53
Effect of nedocromil sodium on non-adrenergic, non-cholinergic neural responses in guinea pig bronchi in vitro
Lindén A; Bergendal A; Lötvall J; Skoogh BE; Löfdahl CG
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;159(5):1423-1428
Neutrophil recruitment by interleukin-17 into rat airways in vivo -: Role of tachykinins
Hoshino H; Lötvall J; Skoogh BE; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 1999;162(4):2347-2352
Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
Laan M; Cui ZH; Hoshino H; Lötvall J; Sjöstrand M; Gruenert DC; Skoogh BE; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(5):1062-1066
Effect of a novel PACAP-27 analogue on muscarinic airway responsiveness in guinea-pigs in vivo
Okazawa A; Cui ZH; Lotvall J; Yoshihara S; Skoogh BE; Kashimoto K; Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1998;124(6):1065-1068
Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger
Cardell LO; Ueki IF; Stjärne P; Agusti C; Takeyama K; Lindén A; Nadel JA
Article: BIOMEDICAL RESEARCH-TOKYO. 1998;19(1):39-44
Sustained relaxant action of [Arg^15,20,21, Leu¹⁷]-PACAP-27-NH₂ on carbachol-induced contraction of guinea-pig tracheal smooth muscle in vitro
Yamada Y; Yoshihara S; Kashimoto K; Linden A; Ichimura T
Article: PEPTIDES. 1998;19(3):593-597
A novel long-acting VIP analog in the guinea pig trachea in vitro
Yoshihara S; Lindén A; Kashimoto K; Watanabe S
Article: PEPTIDES. 1998;19(1):93-98
PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo
Lindén A; Cardell LO; Yoshihara S; Stjärne P; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(8):1730-1734
Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro
Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Article: PEPTIDES. 1997;18(6):843-846
Functional type II VIP-PACAP receptors in human airway epithelial-like cells
Linden A; Yoshihara S; Cardell LO; Kaneko T; Stjarne P; Nadel JA
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(5):L838-L843
Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways
Massion PP; Linden A; Inoue H; Mathy M; Grattan KM; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;119(2):402-406
Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells
Linden A
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1996;97(3):756-760
Tachykinins mediate the potentiation of antigen-induced bronchoconstriction by cold air in guinea pigs
Yoshihara S; Geppetti P; Lindan A; Hara M; Chan BD; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;117(6):1009-1015
Extent of salmeterol-mediated reassertion of relaxation in guineapig trachea pretreated with aliphatic side chain structural analogues
Bergendal A; Linden A; Skoogh BE; Gerspacher M; Anderson GP; Lofdahl CG
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;296(3):291-296
Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs
Yoshihara S; Geppetti P; Hara M; Linden A; Ricciardolo FLM; Chan B; Nadel JA
Article: LUNG. 1996;174(3):159-170
Relaxation kinetics of formoterol and salmeterol in the guinea pig trachea in vitro
Anderson P; Lotvall J; Linden A
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;280(2):113-118
CORTICOTROPIN-RELEASING FACTOR INHIBITS ANTIGEN-INDUCED PLASMA EXTRAVASATION IN AIRWAYS
YOSHIHARA S; RICCIARDOLO FLM; GEPPETTI P; LINDEN A; HARA M; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;115(6):913-916
INHIBITION OF BRONCHOCONSTRICTION BY PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP-1-27) IN GUINEA-PIGS IN-VIVO
LINDEN A; YOSHIHARA S; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;114(7):1478-1482
DIFFERENT EFFECTS OF SALMETEROL, FORMOTEROL AND SALBUTAMOL ON CHOLINERGIC RESPONSES IN THE FERRET TRACHEA
BERGENDAL A; LINDEN A; LOTVALL J; SKOOGH BE; LOFDAHL CG
Journal article: CLINICAL AND EXPERIMENTAL ALLERGY. 1994;24(6):582-589
ROLE OF EICOSANOIDS IN AIR-FLOW OBSTRUCTION AND AIRWAY PLASMA EXUDATION INDUCED BY TRIMELLITIC ANHYDRIDE-CONJUGATE IN GUINEA-PIGS 3 AND 8 WEEKS AFTER SENSITIZATION
ARAKAWA H; LOTVALL J; LINDEN A; KAWIKOVA I; LOFDAHL CG; SKOOGH BE
Journal article: RESPIRATORY MEDICINE. 1994;88(4):249-265
NANC RESPONSES - ROLE IN CONTROL OF AIRWAY TONE
LINDEN A; SKOOGH BE
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1994;7(3):569-578
WHY ARE LONG-ACTING BETA-ADRENOCEPTOR AGONISTS LONG-ACTING
ANDERSON GP; LINDEN A; RABE KF
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1993;109(3):845-851
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION IN GUINEA-PIG BRONCHI - POWERFUL AND FREQUENCY-DEPENDENT STABILIZING EFFECT ON TONE
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: THORAX. 1993;48(5):547-553
SALMETEROL, FORMOTEROL, AND SALBUTAMOL IN THE ISOLATED GUINEA-PIG TRACHEA - DIFFERENCES IN MAXIMUM RELAXANT EFFECT AND POTENCY BUT NOT IN FUNCTIONAL ANTAGONISM
LINDEN A; BERGENDAL A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: EUROPEAN RESPIRATORY JOURNAL. 1993;6(3):425-433
NONADRENERGIC, NONCHOLINERGIC RESPONSES STABILIZE SMOOTH-MUSCLE TONE, WITH AND WITHOUT PARASYMPATHETIC ACTIVATION, IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: ALLERGY. 1992;47(4):384-387
ONSET OF ACTION AND DURATION OF EFFECT OF FORMOTEROL AND SALMETEROL COMPARED TO SALBUTAMOL IN ISOLATED GUINEA-PIG TRACHEA WITH OR WITHOUT EPITHELIUM
ULLMAN A; BERGENDAL A; LINDEN A; WALDECK B; SKOOGH BE; LOFDAHL CG
Journal article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1992;71(1):41-44
INVITRO TACHYPHYLAXIS TO ISOPRENALINE IN GUINEA-PIG TRACHEA - INFLUENCE OF THEOPHYLLINE
BERGENDAL A; LINDEN A; LOTVALL J; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1992;106(3):616-622
THE NONADRENERGIC, NONCHOLINERGIC RESPONSE COUNTERACTS CHANGES IN GUINEA-PIG AIRWAY TONE WITH AND WITHOUT SYMPATHETIC ACTIVATION
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 1991;104(2):509-513
NONADRENERGIC, NONCHOLINERGIC NEURAL ACTIVATION STABILIZES SMOOTH-MUSCLE TONE INDEPENDENTLY OF EICOSANOID FACTORS IN GUINEA-PIG ISOLATED AIRWAYS
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
Journal article: ACTA PHYSIOLOGICA. 1991;142(3):351-357
INVITRO CHARACTERISTICS OF SPONTANEOUS AIRWAY TONE IN THE GUINEA-PIG
LINDEN A; LOFDAHL CG; ULLMAN A; SKOOGH BE
Journal article: PULMONARY PHARMACOLOGY. 1991;4(3):170-176
NONADRENERGIC, NONCHOLINERGIC REGULATION OF GUINEA-PIG AIRWAY SMOOTH-MUSCLE INDOMETHACIN-INDUCED CHANGES AND SEGMENTAL DIFFERENCES
LINDEN A; ULLMAN A; SKOOGH BE; LOFDAHL CG
Journal article: PULMONARY PHARMACOLOGY. 1990;3(3):155-160
Epithelium-derived PGE2 inhibits the contractile response to cholinergic stimulation in isolated ferret trachea.
Ullman A; Ciabattoni G; Löfdahl CG; Lindén A; Svedmyr N; Skoogh BE
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Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa4192
Microbiology in Swedish patients with bronchiectasis and comorbid airway disease: Data from a tertiary European Bronchiectasis registry (EMBARC) center
Osman N; Ghosh P; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa1227
Assessment of small airway dysfunction and symptoms in COPD
Lazarinis N; Panagiotou A; Ramos Ramirez P; Ehlin A; Ridderby A; Pournaras N; Bossios A; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2024;64:pa3319
Infection with P. aeruginosa and H. influenzae in relation to QoL and symptoms in bronchiectasis patients requiring intravenous antibiotics; data from a European Bronchiectasis Registry (EMBARC) center.
Ghosh P; Osman N; Sande M; Lazarinis N; Chalmers JD; Linden A; Bossios A
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2024;18(7):539-552
Small airways disease in chronic obstructive pulmonary disease
Lazarinis N; Fouka E; Linden A; Bossios A
Preprint: RESEARCH SQUARE. 2023
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Käck U; Che KF; Brundin B; Konradsen JR; Linden A
Preprint: AUTHOREA. 2023
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Kovach MA; Käck U; F KC; Brundin B; Konradsen JR; Lindén A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a2520
The Anti-inflammatory Club Cell Protein 16 Is Decreased in Human Airways After Intrabronchial Lipopolysaccharide (LPS) Exposure
Cardenas EI; Smith M; Qvarfordt I; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;207:a4790
Regulatory T Cells Expressing Toll-like Receptor 2 in Blood From Smokers With Stable Chronic Obstructive Pulmonary Disease
Linden A; Malmhall C; Molnar A; Andersson A; Sjostrand M; Bossios A
Preprint: BIORXIV. 2022
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak M; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas E; Villa V; Ricciarelli R; Sandberg J; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay A; Pernemalm M; Lindén A; Klingström J; El Andaloussi S; Ezzat K
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a2410
Glucose Turnover and Neutrophil-Related Cytokines in Smokers With and Without Chronic Obstructive Pulmonary Disease
Pournaras N; Andersson A; Melissa K; Padra M; Che KF; Brundin B; Bozinovski S; Linden K; Jansson P; Skold M; Qvarfordt I; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a1976
Increased Cytotoxic T Cells in the Large Airways in Adults Born Prematurely with a History of Bronchopulmonary Dysplasia
Gao J; Um-Bergstrom PJ; Pourbazargan M; Berggren-Brostrom E; Li C; Merikallio H; Riitta K; Reinke S; Wheelock CE; Melen E; Linden A; Wheelock AM; Rassidaki G; Ortiz-Villalon C; Skold CM
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;205:a2203
Heparin-Binding Protein Is Increased in the Lung After Intrabronchial Endotoxin Exposure
Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Editorial comment: RESPIROLOGY. 2021;26(11):1012-1013
IL-17A: A promising target in viral lung infections
Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:pa3829
Systemic interleukin-26 relates to the risk of exacerbations in smokers with COPD and chronic bronchitis
Lundgren R; Andelid K; Ezerskyte M; Pournaras N; Brundin B; Che KF; Linden A
Editorial comment: THORAX. 2021;76(5):503-507
Early-life risk factors for reversible and irreversible airflow limitation in young adults: findings from the BAMSE birth cohort
Wang G; Kull I; Bergstrom A; Hallberg J; Bergstrom PU; Guerra S; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Janson C; Linden A; Melen E
Review: CYTOKINE & GROWTH FACTOR REVIEWS. 2021;57:1-10
Interleukin-26 in host defense and inflammatory disorders of the airways
Che KF; Tengvall S; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:3371
Structural changes on high resolution computed tomography (HRCT) in adult individuals with a history of bronchopulmonary dysplasia (BPD)
Pourbazargan M; Nyren S; Um-Bergstrom P; Berggren-Brostrom E; Melen E; Steern R; Wheelock AM; Linden A; Karimi R; Skold CM
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:2333
Klebsiella pneumonae triggers rapid release IL(IL)-26 in human neutrophils
Che K; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:432
Assessment of chronic bronchitis in young adults - results from the BAMSE cohort
Wang G; Hallberg J; Bergstrom PU; Janson C; Pershagen G; Georgelis A; Bergstrom A; Kull I; Linden A; Melen E
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2020;201:a3989
Priming with RhIL-26 Modulates the Cytokine Response to Klebsiella Pneumoniae in Monocyte-Derived Macrophages
Che KF; Rekha R; Bergman P; Linden A
Preprint: PREPRINTS.ORG. 2019
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Wright A; Andaloussi SE; Linden A; Ezzat K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa5453
The release of interleukin-26 from alveolar type II cells and its response to stimuli from Gram-negative and Gram-positive bacteria
Tabacaru G; Linden A; Che K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2019;54:pa3320
Chronic airflow limitation and respiratory symptoms among smokers and never smokers
Toren KO; Schioler L; Lindberg A; Andersson A; Behndig A; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Johnsson A; Lindberg E; Linden A; Malinovschi A; Persson L; Tanash H; Vikgren J; Ostgren C-J; Wollmer P; Sandelin M; Strom J; Skold M
Conference publication: 2019;:pa4317
Glucose tolerance and mobilization of neutrophils in smokers with and without chronic obstructive pulmonary disease
Pournaras N; Andersson A; Kovach M; Ganguly K; Padra M; Asgeirsdottir H; Che K; Levänen B; Lindén S; Jansson P-A; Qvarfordt I; Lindén A
Conference publication: 2019;:pa4349
Alterations in measures of systemic inflammation among adults born preterm
Gao J; Um-Bergström P; Pourbazargan M; Berggren-Broström E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock C; Melén E; Lindén A; Wheelock A; Sköld M
Preprint: PREPRINTS.ORG. 2019
Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology
Malmberg M; Malm T; Gustafsson O; Wright A; Andaloussi SE; Linden A; Ezzat K
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa5480
Interleukin-26 in airway morbidities of long-term tobacco smokers
Che K; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold MC; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa960
T-cell subsets in bronchoalveolar lavage fluid from adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Pourbazargan M; Levanen B; Strom M; Berggren-Brostroom E; Melen E; Wheelock A; Linden A; Skold M
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1376
Late Breaking Abstract - Systemic IL-26 correlates with improved asthma control in children with allergic sensitization
Kovach M; Kack U; Che K; Levanen B; Lilja G; Konradsen J; Linden A
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:pa1980
Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia (BPD)
Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson M; Nyren S; Lilja G; Linden A; Wheelock A; Melen E; Skold M
Meeting abstract: EUROPEAN RESPIRATORY JOURNAL. 2018;52:oa4920
Late Breaking Abstract - Elevated airway lymphocytes in adults born prematurely with a history of bronchopulmonary dysplasia
Gao J; Um-Bergstrom P; Pourbazargan M; Berggren-Brostrom E; Merikallio H; Kaarteenaho R; Reinke S; Wheelock CE; Melen E; Linden A; Wheelock AM; Skold CM
Conference publication: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2018;75(Suppl 2):a435-a436
1098 A population based longitudinal study of risk for chronic obstructive pulmonary disease and occupational exposure to organic and inorganic dust
Grahn K; Gustavsson P; Andersson T; Lindén A; Hemmingsson T; Wiebert P
Review: EUROPEAN RESPIRATORY REVIEW. 2018;27(147):170122
Cadmium in tobacco smokers: a neglected link to lung disease?
Ganguly K; Levanen B; Palmberg L; Akesson A; Linden A
Preprint: BIORXIV. 2018
The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation
Ezzat K; Pernemalm M; Pålsson S; Roberts T; Järver P; Dondalska A; Bestas B; Sobkowiak M; Levänen B; Sköld M; Thompson E; Saher O; Kari O; Lajunen T; Ekström ES; Nilsson C; Ishchenko Y; Ishchenko Y; Malm T; Wood MJA; Power U; Masich S; Lindén A; Sandberg J; Lehtiö J; Spetz A-L; Andaloussi SEL
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:757
Interleukin 8 (IL-8), but not GRO-a, associates with carotid intima-media thickness. Results from the IMPROVE study
Velasquez IM; Malarstig A; Baldassarre D; Silveira A; Veglia F; Leander K; Tremoli E; Humphries S; Linden A; Hamsten A; De Faire U; Strawbridge RJ; Gigante B
Conference publication: 2017;:pa990
Endotoxin-induced release of the Th17-associated cytokine interleukin (IL)-26 in human neutrophils
Che K; Linden A
Conference publication: 2017;:oa4846
Late Breaking Abstract - IL-36 receptor agonists contribute to a pro-inflammatory milieu in smokers with and without COPD
Kovach M; Levanen B; Andersson A; Asgeirsdottir H; Prada M; Linden S; Qvarfordt I; Standiford T; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2017;50:pa3554
Endotoxin exposure increases LL-37, but not calprotectin, in healthy human airways
Smith M; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Impact Of Tobacco Smoking On Extracellular Il-17a Protein In The Peripheral Airways
Levanen B; Glader P; Dahlen B; Billing B; Palmberg L; Qvarfordt I; Larsson K; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Modulation Of Tlr3-Stimulated Release Of Il-26 By Il-17a And Il-22 In Bronchial Epithelial Cells
Che KF; Palmberg L; Linden A
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193
Cadmium In The Peripheral Airways Of Tobacco Smokers With And Without COPD
Levanen B; Sundblad B-M; Ji J; Midander K; Julander A; Che KF; Larsson K; Palmberg L; Linden A
Review: JOURNAL OF INNATE IMMUNITY. 2016;8(1):15-22
Interleukin-26: An Emerging Player in Host Defense and Inflammation
Tengvall S; Che KF; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5110
LSC Abstract - Interleukin-26 in antibacterial host defense of human lungs: Effects on neutrophil mobilization
Che KF; Tengvall S; Levanen B; Silverpil E; Smith M; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa873
Hypoxia associated with increased systemic concentrations of MPO and NE during exacerbations of COPD
Andelid K; Glader P; Yoshihara S; Andersson A; Ekberg-Jansson A; Linden A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2015;46:pa5102
Tobacco smoke causes release of IL-16 protein from NK cells in vitro
Andersson A; Malmhall C; Linden A; Bossios A
Conference publication: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;135(2):AB180
Systemic IL-17 Signaling Relates to Gender, Disease Severity and Use of Oral Steroids in Children with Asthma
Alavi MM; Nordlund B; Thunberg S; Gronlund H; Lundahl J; Hedlin G; Linden A; Konradsen J
Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2015;191
Signaling Mechanisms And Release Of Il-26 In Human Structural Lung Cells In Response To Pathogen Associated Molecular Patterns
Che KF; Ji J; Palmberg L; Skold M; Linden A
Book chapter: IL-17, IL-22 AND THEIR PRODUCING CELLS: ROLE IN INFLAMMATION AND AUTOIMMUNITY: PROGRESS IN INFLAMMATION RESEARCH. 2013;p. 259-272
Involvement of Interleukin-17 Cytokines in Human Asthma
Lindén A
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2012;6(2):173-186
IL-17 in human asthma
Silverpil E; Linden A
Letter: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2011;30(1):113
Phenotyping BOS could improve understanding of mechanisms involved Reply
Riise GC; Linden A
Editorial comment: CLINICAL RESPIRATORY JOURNAL. 2010;4:iii
Preface
Linden A; Larsson K
Conference publication: 2010;:a3825
Circulating Myeloperoxidase During COPD Exacerbations
Andelid K; Glader P; Ekberg-Jansson A; Lindén A
Conference publication: 2010;:a3490
Decreased Interleukin-17A In The Airways Of Patients With Lung Cancer?
Lärstad M; Andersson A; Riise G; Lindén A
Conference publication: 2010;:a5084
IL-17 Involved In The Immune Response To Endotoxin In Human Airways
Glader P; Smith M; Malmhäll C; Sjöstrand M; Qvarfordt I; Lindén A
Conference publication: 2010;:a1290
Macrophages Sources Of IL-22 Protein In Mouse Lungs Exposed To Peptidoglycan Or IL-23
Hansson M; Silverpil E; Glader P; Lindén A
Book chapter: NEW DRUGS AND TARGETS FOR ASTHMA AND COPD: PROGRESS IN RESPIRATORY RESEARCH. 2010;p. 141-149
Targeting interleukin-17 in the lungs
Ivanov S; Lindén A
Review: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS. 2009;9(2):178-186
Impact of IL-17 on cells of the monocyte lineage in health and disease.
Sergejeva S; Lindén A
Conference publication: JOURNAL OF IMMUNOLOGY. 2009;182:47.14
Increased number of systemic T regulatory cells but not Th1 or Th2 cells in tobacco smokers
Malmhall CA; Andersson A; Jackute J; Houltz B; Lotvall J; Linden A; Bossios A
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2009;30(2):95-103
Interleukin-17 as a drug target in human disease
Ivanov S; Linden A
Book chapter: TH 17 CELLS: ROLE IN INFLAMMATION AND AUTOIMMUNE DISEASE: PROGRESS IN INFLAMMATION RESEARCH. 2009;p. 201-209
IL-17 cytokines in asthma
Lindén A
Review: RECENT PATENTS ON INFLAMMATION AND ALLERGY DRUG DISCOVERY. 2008;2(2):82-91
The IL-17 Family of Cytokines - Applications in Respiratory Medicine and Allergology
Laan M; Linden A
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2007;2007(398):re4
A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling.
Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2005;25(1):159-172
Neutrophils, interleukin-17A and lung disease
Lindén A; Laan M; Anderson GP
Published conference paper: REGULATORY PEPTIDES. 2004;123(1-3):161-165
Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi
Yoshihara S; Yamada Y; Abe T; Kashimoto K; Lindén A; Arisaka O
Review: IMMUNITY. 2004;21(4):467-476
Interleukin-17 family members and inflammation
Kolls JK; Lindén A
Review: CURRENT OPINION IN INVESTIGATIONAL DRUGS. 2003;4(11):1304-1312
Rationale for targeting interleukin-17 in the lungs.
Lindén A
Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2003;22:42S
De novo synthesis of IL-17 in human airways following exposure to organic dust
Ivanov S; Prause O; Palmberg L; Larsson K; Lindén A
Review: CURRENT PHARMACEUTICAL DESIGN. 2002;8(20):1855-1861
IL-17 as a potential target for modulating airway neutrophilia
Laan M; Lindén A
Review: ALLERGY. 2002;57(9):769-775
Neutrophilic airway inflammation and IL-17
Lindén A; Adachi M
Review: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2001;126(3):179-184
Role of interleukin-17 and the neutrophil in asthma
Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2000;15(5):973-977
Airway neutrophils and interleukin-17
Lindén A; Hoshino H; Laan M
Review: EUROPEAN RESPIRATORY JOURNAL. 1999;14(2):443-451
Bronchodilation by pituitary adenylate cyclase-activating peptide and related peptides
Lindén A; Cardell LO; Yoshihara S; Nadel JA
Review: PULMONARY PHARMACOLOGY & THERAPEUTICS. 1999;12(4):229-236
PACAPs -: Potential for bronchodilation
Lindén A
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1996;805:536-542
A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea
Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Review: GENERAL PHARMACOLOGY: THE VASCULAR SYSTEM. 1996;27(7):1109-1121
NANC neural control of airway smooth muscle tone
Linden A
Review: LUNG. 1996;174(1):1-22
Pharmacological basis for duration of effect: Formoterol and salmeterol versus short-acting beta(2)-adrenoceptor agonists
Linden A; Rabe KF; Lofdahl CG
Conference publication: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1993;72:28-29
THE NANC SYSTEM AS A STABILIZER OF AIRWAY SMOOTH-MUSCLE TONE
LINDEN A; ULLMAN A; LOFDAHL CG; SKOOGH BE
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