Anders Lindén

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Publications
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About me

Anders Lindén is a Professor of Lung and Airway Research at the Institute of Environmental Medicine (IMM). His main area of research is deficiencies in the local immune system of the lungs of smokers with and without chronic obstructive pulmonary disease (COPD). The research also concerns severe/chronic asthma, a disease that has some similarities to COPD.

Articles

Article: RESPIRATORY RESEARCH. 2024;25(1):163

Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen

Kovach MA; Kaeck U; Che KF; Brundin B; Konradsen JR; Linden A
Article: GLYCOBIOLOGY. 2023;33(12):1128-1138

Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD

Venkatakrishnan V; Thomsson KA; Padra M; Andersson A; Brundin B; Christenson K; Bylund J; Karlsson NG; Linden A; Linden SK
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2023;10(1):2181291

Comorbid conditions as predictors of mortality in severe COPD - an eight-year follow-up cohort study

Eliasson G; Janson C; Johansson G; Larsson K; Linden A; Loefdahl C-G; Sandstroem T; Sundh J
Article: CURRENT RESEARCH IN TRANSLATIONAL MEDICINE. 2023;71(1):103374

Causal analysis of plasma IL-8 on carotid intima media thickness, a measure of subclinical atherosclerosis

Velasquez IM; Malarstig A; Baldassarre D; Borne Y; de Faire U; Engstrom G; Eriksson P; Giral P; Humphries SE; Kurl S; Leander K; Lind L; Linden A; Orsini N; Pirro M; Silveira A; Smit AJ; Tremoli E; Veglia F; Strawbridge RJ; Gigante B
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1178135

TLR4-mediated release of heparin-binding protein in human airways: a co-stimulatory role for IL-26

Paulsson M; Cardenas EI; Che KF; Brundin B; Smith M; Qvarfordt I; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2022;60(3):2102531

Increased cytotoxic T-cells in the airways of adults with former bronchopulmonary dysplasia

Um-Bergstrom P; Pourbazargan M; Brundin B; Strom M; Ezerskyte M; Gao J; Brostrom EB; Melen E; Wheelock AM; Linden A; Skold CM
Article: RESPIRATORY RESEARCH. 2022;23(1):108

Involvement of IL-26 in bronchiolitis obliterans syndrome but not in acute rejection after lung transplantation

Magnusson JM; Ericson P; Tengvall S; Stockfelt M; Brundin B; Linden A; Riise GC
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2022;16(3):293-301

IL-26 in asthma and COPD

Cardenas EI; Che KF; Konradsen JR; Bao A; Linden A
Article: LAKARTIDNINGEN. 2022;119:21155

[Pharmacological treatment reduces mortality in COPD].

Larsson K; Lindberg A; Sandelowsky H; Lindén A; Ställberg B; Janson C
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:1179-1194

Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD

Pournaras N; Andersson A; Kovach MA; Padra M; Che KF; Brundin B; Yoshihara S; Bozinovski S; Linden SK; Jansson P-A; Skold MC; Qvarfordt I; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2022;17:993-1004

Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)

Lundh L; Larsson K; Linden A; Montgomery S; Palmberg L; Sandelowsky H
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1016991

Increased IL-26 associates with markers of hyperinflammation and tissue damage in patients with acute COVID-19

Cardenas EI; Ekstedt S; Piersiala K; Petro M; Karlsson A; Kagedal A; Georen SK; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;65(6):593-602

Mucin Binding to Moraxella catarrhalis during Airway Inflammation Is Dependent on Sialic Acid

Padra M; Benktander J; Padra JT; Andersson A; Brundin B; Tengvall S; Christenson K; Qvarfordt I; Gad R; Paulsson M; Pournaras N; Linden A; Linden SK
Article: ENVIRONMENTAL RESEARCH. 2021;200:111739

Occupational exposure to particles and increased risk of developing chronic obstructive pulmonary disease (COPD): A population-based cohort study in Stockholm, Sweden

Grahn K; Gustavsson P; Andersson T; Linden A; Hemmingsson T; Selander J; Wiebert P
Article: RESPIRATORY RESEARCH. 2021;22(1):174

Heparin-binding protein in lower airway samples as a biomarker for pneumonia

Paulsson M; Thelaus L; Riesbeck K; Qvarfordt I; Smith ME; Linden A; Linder A
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2021;41(2):181-191

The ratio FEV₁/FVC and its association to respiratory symptoms-A Swedish general population study

Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall JE; Eriksson MJ; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Lennart Persson H; Sandelin M; Eriksson Strom J; Tanash H; Vikgren J; Johan Ostgren C; Wollmer P; Skold CM
Article: EUROPEAN RESPIRATORY JOURNAL. 2021;57(3):2002120

Assessment of chronic bronchitis and risk factors in young adults: results from BAMSE

Wang G; Hallberg J; Bergstrom PU; Janson C; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Bergstrom A; Kull I; Linden A; Melen E
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2021;64(2):173-182

IL-36 Cytokines Promote Inflammation in the Lungs of Long-Term Smokers

Kovach MA; Che K; Brundin B; Andersson A; Asgeirsdottir H; Padra M; Linden SK; Qvarfordt I; Newstead MW; Standiford TJ; Linden A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:761317

Complex Involvement of Interleukin-26 in Bacterial Lung Infection

Che KF; Paulsson M; Piersiala K; Sax J; Mboob I; Rahman M; Rekha RS; Safholm J; Adner M; Bergman P; Cardell L-O; Riesbeck K; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2021;16:367-377

Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations

Sundqvist M; Andelid K; Ekberg-Jansson A; Bylund J; Karlsson-Bengtsson A; Linden A
Article: LAKARTIDNINGEN. 2020;117:20051

[The role of inhaled steroids in the treatment of COPD].

Ställberg B; Janson C; Lindén A; Lisspers K; Larsson K
Article: BMJ OPEN RESPIRATORY RESEARCH. 2020;7(1):e000600

Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study

Toren K; Schioler L; Lindberg A; Andersson A; Behndig AF; Bergstrom G; Blomberg A; Caidahl K; Engvall J; Eriksson M; Hamrefors V; Janson C; Kylhammar D; Lindberg E; Linden A; Malinovschi A; Persson HL; Sandelin M; Strom JE; Tanash HA; Vikgren J; Ostgren CJ; Wollmer P; Skold CM
Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(5):1869-1879

Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

Szmidt MK; Kaluza J; Harris HR; Linden A; Wolk A
Article: CLINICAL SCIENCE. 2020;134(10):1107-1125

Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers

Padra M; Andersson A; Levanen B; Premaratne P; Asgeirsdottir H; Tengvall S; Christenson K; Stockfelt M; Bozinovski S; Yoshihara S; Lantz A-S; Palmberg L; Dahlen B; Larsson K; Qvarfordt I; Linden SK; Linden A
Article: SCIENTIFIC REPORTS. 2020;10(1):2376

Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties

Al-Adwani S; Wallin C; Balhuizen MD; Veldhuizen EJA; Coorens M; Landreh M; Vegvari A; Smith ME; Qvarfordt I; Linden A; Graslund A; Agerberth B; Bergman P
Article: FRONTIERS IN NEUROSCIENCE. 2020;14:256

Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology

Malmberg M; Malm T; Gustafsson O; Sturchio A; Graff C; Espay AJ; Wright AP; El Andaloussi S; Linden A; Ezzat K
Article: JOURNAL OF INNATE IMMUNITY. 2020;12(6):480-489

Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD

Stockfelt M; Christenson K; Andersson A; Bjorkman L; Padra M; Brundin B; Ganguly K; Asgeirsdottir H; Linden S; Qvarfordt I; Bylund J; Linden A
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(4):1134-1136.e10

Enhanced local production of IL-26 in uncontrolled compared with controlled adult asthma

Tufvesson E; Jogdand P; Che KF; Levanen B; Erjefalt JS; Bjermer L; Linden A
Article: NATURE COMMUNICATIONS. 2019;10(1):2331

The viral protein corona directs viral pathogenesis and amyloid aggregation

Ezzat K; Pernemalm M; Palsson S; Roberts TC; Jarver P; Dondalska A; Bestas B; Sobkowiak MJ; Levanen B; Skold M; Thompson EA; Saher O; Kari OK; Lajunen T; Ekstrom ES; Nilsson C; Ishchenko Y; Malm T; Wood MJA; Power UF; Masich S; Linden A; Sandberg JK; Lehtio J; Spetz A-L; EL Andaloussi S
Article: RESPIRATORY RESEARCH. 2019;20(1):102

Pulmonary outcomes in adults with a history of Bronchopulmonary Dysplasia differ from patients with asthma

Um-Bergstrom P; Hallberg J; Pourbazargan M; Berggren-Brostrom E; Ferrara G; Eriksson MJ; Nyren S; Gao J; Lilja G; Linden A; Wheelock AM; Melen E; Skold CM
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(5):907-916

Alcohol Consumption and Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men

Kaluza J; Harris HR; Linden A; Wolk A
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(2):665-672

Long-term unprocessed and processed red meat consumption and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

Kaluza J; Harris H; Linden A; Wolk A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:956

Pharmacological Modulation of Endotoxin-Induced Release of IL-26 in Human Primary Lung Fibroblasts

Che KF; Sun J; Linden A
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(6):1897-1909

Long-term consumption of fruits and vegetables and risk of chronic obstructive pulmonary disease: a prospective cohort study of women

Kaluza J; Harris HR; Linden A; Wolk A
Article: CLINICAL SCIENCE. 2018;132(9):959-983

The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers

Che KF; Tufvesson E; Tengvall S; Lappi-Blanco E; Kaarteenaho R; Levanen B; Ekberg M; Brauner A; Wheelock AM; Bjermer L; Skold CM; Linden A
Article: EPIDEMIOLOGY. 2018;29(2):254-260

Dietary Fiber Intake and Risk of Chronic Obstructive Pulmonary Disease A Prospective Cohort Study of Men

Kaluza J; Harris H; Wallin A; Linden A; Wolk A
Article: FRONTIERS IN MICROBIOLOGY. 2018;9:1559

Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing

Paulsson M; Che KF; Ahi J; Tham J; Sandblad L; Smith ME; Qvarfordt I; Su Y-C; Linden A; Riesbeck K
Article: MOLECULAR MEDICINE. 2017;23:247-257

Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines

Che KF; Kaarteenaho R; Lappi-Blanco E; Levanen B; Sun J; Wheelock A; Palmberg L; Skold CM; Linden A
Article: THORAX. 2017;72(6):500-509

Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men

Kaluza J; Larsson SC; Orsini N; Linden A; Wolk A
Article: EUROPEAN CLINICAL RESPIRATORY JOURNAL. 2017;4(1):1270079

Characterization of secondary care for COPD in Sweden.

Sundh J; Janson C; Johansson G; Lindén A; Löfdahl C-G; Sandström T; Larsson K
Article: JOURNAL OF INNATE IMMUNITY. 2017;9(5):475-482

Endotoxin Exposure Increases LL-37-but Not Calprotectin - in Healthy Human Airways

Smith ME; Stockfelt M; Tengvall S; Bergman P; Linden A; Qvarfordt I
Article: PLOS ONE. 2017;12(12):e0188909

Recombinant human IL-26 facilitates the innate immune response to endotoxin in the bronchoalveolar space of mice in vivo

Bao A; Che KF; Bozinovski S; Ji J; Gregory JA; Georen SK; Adner M; Cardell L-O; Linden A
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2016;184(11):829-836

Consumption of Unprocessed and Processed Red Meat and the Risk of Chronic Obstructive Pulmonary Disease: A Prospective Cohort Study of Men

Kaluza J; Larsson SC; Linden A; Wolk A
Article: RESPIRATORY RESEARCH. 2016;17:32

The cytokine interleukin-26 as a biomarker in pediatric asthma

Konradsen JR; Nordlund B; Levanen B; Hedlin G; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2245-2258

Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD

Andersson A; Malmhall C; Houltz B; Tengvall S; Sjostrand M; Qvarfordt I; Linden A; Bossios A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:2109-2116

Impact of tobacco smoking on cytokine signaling via interleukin-17A in the peripheral airways

Levanen B; Glader P; Dahlen B; Billing B; Qvarfordt I; Palmberg L; Larsson K; Linden A
Article: PLOS ONE. 2016;11(10):e0164751

Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function

Ostadkarampour M; Muller M; Ockinger J; Kullberg S; Linden A; Eklund A; Grunewald J; Wahlstrom J
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2016;11:1005-1013

Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation

Sundblad B-M; Ji J; Levanen B; Midander K; Julander A; Larsson K; Palmberg L; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:1253-1263

Systemic signs of neutrophil mobilization during clinically stable periods and during exacerbations in smokers with obstructive pulmonary disease

Andelid K; Andersson A; Yoshihara S; Ahren C; Jirholt P; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:689-702

Systemic cytokine signaling via IL-17 in smokers with obstructive pulmonary disease: a link to bacterial colonization?

Andelid K; Tengvall S; Andersson A; Levanen B; Christenson K; Jirholt P; Ahren C; Qvarfordt I; Ekberg-Jansson A; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:2327-2334

The phenotype of concurrent chronic bronchitis and frequent exacerbations in patients with severe COPD attending Swedish secondary care units

Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Sandstrom T; Janson C
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2015;10:173-183

Comorbidity and health-related quality of life in patients with severe chronic obstructive pulmonary disease attending Swedish secondary care units

Sundh J; Johansson G; Larsson K; Linden A; Lofdahl C-G; Janson C; Sandstrom T
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014;190(9):1022-1031

Interleukin-26 in Antibacterial Host Defense of Human Lungs Effects on Neutrophil Mobilization

Che KF; Tengvall S; Levanen B; Silverpil E; Smith ME; Awad M; Vikstrom M; Palmberg L; Qvarfordt I; Skold M; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2014;44(5):1319-1331

Interleukin-17 cytokine signalling in patients with asthma

Linden A; Danlen B
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2014;178(2):342-352

Higher levels of interleukin IL-17 and antigen-specific IL-17 responses in pulmonary sarcoidosis patients with Lofgren's syndrome

Ostadkarampour M; Eklund A; Moller D; Glader P; Hoglund CO; Linden A; Grunewald J; Wahlstrom J
Article: INNATE IMMUNITY. 2013;19(5):479-492

Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation

Silverpil E; Wright AKA; Hansson M; Jirholt P; Henningsson L; Smith ME; Gordon SB; Iwakura Y; Gjertsson I; Glader P; Linden A
Article: INFLAMMATION RESEARCH. 2013;62(6):561-569

Interleukin-22 produced by alveolar macrophages during activation of the innate immune response

Hansson M; Silverpil E; Linden A; Glader P
Article: PLOS ONE. 2013;8(9):e75032

Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects

Smith ME; Bozinovski S; Malmhall C; Sjostrand M; Glader P; Venge P; Hiemstra PS; Anderson GP; Linden A; Qvarfordt I
Article: LAKARTIDNINGEN. 2011;108(35):1604-1605

[How the care of COPD will be better].

Larsson K; Löfdahl C-G; Lindén A; Sandström T; Johansson GS
Article: INNATE IMMUNITY. 2011;17(2):204-211

¹H and hyperpolarized ³He magnetic resonance imaging clearly detect the preventative effect of a glucocorticoid on endotoxin-induced pulmonary inflammation in vivo

Olsson LE; Smailagic A; Onnervik P-O; Linden A; Hockings PD
Article: INFLAMMATION. 2011;34(1):1-9

Impact of Interleukin-17 on Macrophage Phagocytosis of Apoptotic Neutrophils and Particles

Silverpil E; Glader P; Hansson M; Linden A
Article: INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE. 2011;6:83-88

A gender difference in circulating neutrophils in malnourished patients with COPD

Larsson S; Nordenson A; Glader P; Yoshihara S; Linden A; Slinde F
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2011;300(1):L43-L55

Effects of tobacco smoke on IL-16 in CD8⁺ cells from human airways and blood: a key role for oxygen free radicals?

Andersson A; Bossios A; Malmhall C; Sjostrand M; Eldh M; Eldh B-M; Glader P; Andersson B; Qvarfordt I; Riise GC; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2010;36(5):1155-1164

Interleukin-17-producing T-helper cells and related cytokines in human airways exposed to endotoxin

Glader P; Smith ME; Malmhall C; Balder B; Sjostrand M; Qvarfordt I; Linden A
Article: INFECTION AND IMMUNITY. 2010;78(9):3783-3790

Interleukin-17A during Local and Systemic Staphylococcus aureus-Induced Arthritis in Mice

Henningsson L; Jirholt P; Lindholm C; Eneljung T; Silverpil E; Iwakura Y; Linden A; Gjertsson I
Article: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2010;29(7):800-807

Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome

Riise GC; Ericson P; Bozinovski S; Yoshihara S; Anderson GP; Linden A
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010;182(1):34-40

Neutralizing Granulocyte/Macrophage Colony-Stimulating Factor Inhibits Cigarette Smoke-induced Lung Inflammation

Vlahos R; Bozinovski S; Chan SPJ; Ivanov S; Linden A; Hamilton JA; Anderson GP
Article: RESPIRATORY RESEARCH. 2009;10(1):94

West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma

Lotvall J; Ekerljung L; Ronmark EP; Wennergren G; Linden A; Ronmark E; Toren K; Lundback B
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2009;22(3):199-207

IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy

Prause O; Bossios A; Silverpil E; Ivanov S; Bozinovski S; Vlahos R; Sjostrand M; Anderson GP; Linden A
Article: EUROPEAN RESPIRATORY JOURNAL. 2008;32(3):644-650

Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space

Glader P; Eldh B; Bozinovski S; Andelid K; Sjostrand M; Malmhall C; Anderson GP; Riise GC; Qvarfordt I; Linden A
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(5):480-488

Prolonged eosinophil production after allergen exposure in IFN-γR KO mice is IL-5 dependent

Zhao L-L; Lotvall J; Linden A; Tomaki M; Sjostrand M; Bossios A
Article: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2007;1(2):279-293

Th-17 cells in the lungs?

Ivanov S; Lindén A
Article: RESPIRATORY MEDICINE. 2007;101(5):888-895

Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms

Andelid K; Bake B; Rak S; Linden A; Rosengren A; Ekberg-Jansson A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2007;36(4):442-451

Functional relevance of the IL-23-IL-17 axis in lungs in vivo

Ivanov S; Bozinovski S; Bossios A; Valadi H; Vlahos R; Malmhall C; Sjostrand M; Kolls JK; Anderson GP; Linden A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2006;144(2):212-216

Association of epithelial damage and signs of neutrophil mobilization in the airways during acute exacerbations of paediatric asthma

Yoshihara S; Yamada Y; Abe T; Lindén A; Arisaka O
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2006;19(1):47-50

Interleukin-17 and airway remodelling

Lindén A
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2005;33(3):248-253

Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation

Sergejeva S; Ivanov S; Lötvall J; Lindén A
Article: RESPIRATORY RESEARCH. 2005;6(1):44

Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust -: art. no. 44

Ivanov S; Palmberg L; Venge P; Larsson K; Lindén A
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2004;138(1):75-82

Impact of tobacco smoke on interleukin-16 protein in human airways, lymphoid tissue and T lymphocytes

Andersson A; Qvarfordt I; Laan M; Sjöstrand M; Malmhäll C; Riise GC; Cardell LO; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2004;24(2):231-237

β-adrenoceptor stimulation and neutrophil accumulation in mouse airways

Miyamoto M; Tomaki M; Lötvall J; Lindén A
Article: THORAX. 2004;59(4):313-317

Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways

Prause O; Bozinovski S; Anderson GP; Lindén A
Article: REGULATORY PEPTIDES. 2004;117(2):149-154

A synthetic VIP peptide analogue inhibits neutrophil recruitment in rat airways in vivo

Sergejeva S; Hoshino H; Yoshihara S; Kashimoto K; Lötvall J; Lindén A
Article: RESPIRATORY MEDICINE. 2004;98(2):159-163

BAL levels of interleukin-18 do not change before or during acute rejection in lungtransplant recipients

Ericson P; Lindén A; Riise GC
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;133(2):290-296

IL-16 in the airways of lung allograft recipients with acute rejection or obliterative bronchiolitis

Laan M; Lindén A; Riise GC
Article: JOURNAL OF IMMUNOLOGY. 2003;170(9):4665-4672

Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways

Miyamoto M; Prause O; Sjöstrand M; Laan M; Lötvall J; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;21(3):387-393

A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF-α

Laan M; Prause O; Miyamoto M; Sjöstrand M; Hytönen AM; Kaneko T; Löotvall J; Lindén A
Article: THORAX. 2003;58(3):217-221

Bronchodilation by an inhaled VPAC₂ receptor agonist in patients with stable asthma

Lindén A; Hansson L; Andersson A; Palmqvist M; Arvidsson P; Löfdahl CG; Larsson P; Lötvall J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;462(1-3):193-198

Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells

Prause O; Laan M; Lötvall J; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(3):534-537

Free, soluble interleukin-17 protein during severe inflammation in human airways

Laan M; Palmberg L; Larsson K; Lindén A
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2002;15(2):161-168

Comparison of effects of Anti-IL-3, IL-5 and GM-CSF treatments on eosinophilopoiesis and airway eosinophilia induced by allergen

Tomaki M; Zhao LL; Sjöstrand M; Lindén A; Ichinose M; Lötvall J
Article: PEPTIDES. 2001;22(12):2151-2154

Pituitary adenylate cyclase-activating peptide inhibits neutrophil chemotaxis

Kinhult J; Uddman R; Laan M; Lindén A; Cardell LO
Article: ALLERGY. 2001;56(9):871-877

Effect of seasonal allergen exposure on mucosal IL-16 and CD4+cells in patients with allergic rhinitis

Pullerits T; Lindén A; Malmhäll C; Lötvall J
Article: EUROPEAN RESPIRATORY JOURNAL. 2001;17(5):872-880

Reduced late asthmatic response by repeated low-dose allergen exposure

Palmqvist M; Cui ZH; Sjöstrand M; Lindén A; Lötvall J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2001;133(1):200-206

IL-17-induced cytokine release in human bronchial epithelial cells in vitro:: role of mitogen-activated protein (MAP) kinases

Laan M; Lötvall J; Chung KF; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 2000;165(7):4040-4050

Eosinophilopoiesis in a murine model of allergic airway eosinophilia:: Involvement of bone marrow IL-5 and IL-5 receptor α

Tomaki M; Zhao LL; Lundahl J; Sjöstrand M; Jordana M; Lindén A; O'Byrne P; Lötvall J
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1469-1475

Upregulation of nasal mucosal eotaxin in patients with allergic rhinitis during grass pollen season:: effect of a local glucocorticoid

Pullerits T; Lindén A; Praks L; Cardell LO; Lötvall J
Article: ALLERGY. 2000;55(8):749-756

IL-12 regulates bone marrow eosinophilia and airway eotaxin levels induced by airway allergen exposure

Zhao LL; Lindén A; Sjöstrand M; Cui ZH; Lötvall J; Jordana M
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):143-149

Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo

Hoshino H; Laan M; Sjöstrand M; Lötvall J; Skoogh BE; Lindén A
Article: THORAX. 1999;54(10):911-916

Increased levels of interleukin-16 in the airways of tobacco smokers:: relationship with peripheral blood T lymphocytes

Laan M; Qvarfordt I; Riise GC; Andersson BA; Larsson S; Lindén A
Article: REGULATORY PEPTIDES. 1999;81(1-3):49-53

Effect of nedocromil sodium on non-adrenergic, non-cholinergic neural responses in guinea pig bronchi in vitro

Lindén A; Bergendal A; Lötvall J; Skoogh BE; Löfdahl CG
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;159(5):1423-1428

Neutrophil recruitment by interleukin-17 into rat airways in vivo -: Role of tachykinins

Hoshino H; Lötvall J; Skoogh BE; Lindén A
Article: JOURNAL OF IMMUNOLOGY. 1999;162(4):2347-2352

Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways

Laan M; Cui ZH; Hoshino H; Lötvall J; Sjöstrand M; Gruenert DC; Skoogh BE; Lindén A
Article: EUROPEAN RESPIRATORY JOURNAL. 1998;12(5):1062-1066

Effect of a novel PACAP-27 analogue on muscarinic airway responsiveness in guinea-pigs in vivo

Okazawa A; Cui ZH; Lotvall J; Yoshihara S; Skoogh BE; Kashimoto K; Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1998;124(6):1065-1068

Bronchodilatation in vivo by carbon monoxide, a cyclic GMP related messenger

Cardell LO; Ueki IF; Stjärne P; Agusti C; Takeyama K; Lindén A; Nadel JA
Article: BIOMEDICAL RESEARCH-TOKYO. 1998;19(1):39-44

Sustained relaxant action of [Arg^15,20,21, Leu¹⁷]-PACAP-27-NH₂ on carbachol-induced contraction of guinea-pig tracheal smooth muscle in vitro

Yamada Y; Yoshihara S; Kashimoto K; Linden A; Ichimura T
Article: PEPTIDES. 1998;19(1):93-98

PACAP 1-38 as an inhaled bronchodilator in guinea pigs in vivo

Lindén A; Cardell LO; Yoshihara S; Stjärne P; Nadel JA
Article: PEPTIDES. 1998;19(3):593-597

A novel long-acting VIP analog in the guinea pig trachea in vitro

Yoshihara S; Lindén A; Kashimoto K; Watanabe S
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1997;121(8):1730-1734

Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro

Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Article: PEPTIDES. 1997;18(6):843-846

Functional type II VIP-PACAP receptors in human airway epithelial-like cells

Linden A; Yoshihara S; Cardell LO; Kaneko T; Stjarne P; Nadel JA
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;271(5):L838-L843

Dimethyl sulfoxide decreases interleukin-8-mediated neutrophil recruitment in the airways

Massion PP; Linden A; Inoue H; Mathy M; Grattan KM; Nadel JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;119(2):402-406

Increased interleukin-8 release by beta-adrenoceptor activation in human transformed bronchial epithelial cells

Linden A
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;117(6):1009-1015

Extent of salmeterol-mediated reassertion of relaxation in guineapig trachea pretreated with aliphatic side chain structural analogues

Bergendal A; Linden A; Skoogh BE; Gerspacher M; Anderson GP; Lofdahl CG
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;296(3):291-296

Cold air-induced bronchoconstriction is mediated by tachykinin and kinin release in guinea pigs

Yoshihara S; Geppetti P; Hara M; Linden A; Ricciardolo FLM; Chan B; Nadel JA
Article: LUNG. 1996;174(3):159-170

Relaxation kinetics of formoterol and salmeterol in the guinea pig trachea in vitro

Anderson P; Lotvall J; Linden A
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;280(2):113-118

CORTICOTROPIN-RELEASING FACTOR INHIBITS ANTIGEN-INDUCED PLASMA EXTRAVASATION IN AIRWAYS

YOSHIHARA S; RICCIARDOLO FLM; GEPPETTI P; LINDEN A; HARA M; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;115(6):913-916

INHIBITION OF BRONCHOCONSTRICTION BY PITUITARY ADENYLATE-CYCLASE ACTIVATING POLYPEPTIDE (PACAP-1-27) IN GUINEA-PIGS IN-VIVO

LINDEN A; YOSHIHARA S; CHAN B; NADEL JA
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;114(7):1478-1482

DIFFERENT EFFECTS OF SALMETEROL, FORMOTEROL AND SALBUTAMOL ON CHOLINERGIC RESPONSES IN THE FERRET TRACHEA

BERGENDAL A; LINDEN A; LOTVALL J; SKOOGH BE; LOFDAHL CG
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Editorial comment: RESPIROLOGY. 2021;26(11):1012-1013

IL-17A: A promising target in viral lung infections

Linden A
Editorial comment: THORAX. 2021;76(5):503-507

Early-life risk factors for reversible and irreversible airflow limitation in young adults: findings from the BAMSE birth cohort

Wang G; Kull I; Bergstrom A; Hallberg J; Bergstrom PU; Guerra S; Pershagen G; Gruzieva O; van Hage M; Georgelis A; Janson C; Linden A; Melen E
Review: CYTOKINE & GROWTH FACTOR REVIEWS. 2021;57:1-10

Interleukin-26 in host defense and inflammatory disorders of the airways

Che KF; Tengvall S; Linden A
Review: EUROPEAN RESPIRATORY REVIEW. 2018;27(147):170122

Cadmium in tobacco smokers: a neglected link to lung disease?

Ganguly K; Levanen B; Palmberg L; Akesson A; Linden A
Review: JOURNAL OF INNATE IMMUNITY. 2016;8(1):15-22

Interleukin-26: An Emerging Player in Host Defense and Inflammation

Tengvall S; Che KF; Linden A
Review: EXPERT REVIEW OF RESPIRATORY MEDICINE. 2012;6(2):173-186

IL-17 in human asthma

Silverpil E; Linden A
Letter: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2011;30(1):113

Phenotyping BOS could improve understanding of mechanisms involved Reply

Riise GC; Linden A
Editorial comment: CLINICAL RESPIRATORY JOURNAL. 2010;4:iii

Preface

Linden A; Larsson K
Review: ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS. 2009;9(2):178-186

Impact of IL-17 on cells of the monocyte lineage in health and disease.

Sergejeva S; Lindén A
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2009;30(2):95-103

Interleukin-17 as a drug target in human disease

Ivanov S; Linden A
Review: RECENT PATENTS ON INFLAMMATION AND ALLERGY DRUG DISCOVERY. 2008;2(2):82-91

The IL-17 family of cytokines--applications in respiratory medicine and allergology.

Laan M; Linden A
Review: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2007;2007(398):re4

A role for the cytoplasmic adaptor protein Act1 in mediating IL-17 signaling.

Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2005;25(1):159-172

Neutrophils, interleukin-17A and lung disease

Lindén A; Laan M; Anderson GP
Published conference paper: REGULATORY PEPTIDES. 2004;123(1-3):161-165

Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi

Yoshihara S; Yamada Y; Abe T; Kashimoto K; Lindén A; Arisaka O
Review: IMMUNITY. 2004;21(4):467-476

Interleukin-17 family members and inflammation

Kolls JK; Lindén A
Review: CURRENT OPINION IN INVESTIGATIONAL DRUGS. 2003;4(11):1304-1312

Rationale for targeting interleukin-17 in the lungs.

Lindén A
Review: CURRENT PHARMACEUTICAL DESIGN. 2002;8(20):1855-1861

IL-17 as a potential target for modulating airway neutrophilia

Laan M; Lindén A
Review: ALLERGY. 2002;57(9):769-775

Neutrophilic airway inflammation and IL-17

Lindén A; Adachi M
Review: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2001;126(3):179-184

Role of interleukin-17 and the neutrophil in asthma

Lindén A
Review: EUROPEAN RESPIRATORY JOURNAL. 2000;15(5):973-977

Airway neutrophils and interleukin-17

Lindén A; Hoshino H; Laan M
Review: EUROPEAN RESPIRATORY JOURNAL. 1999;14(2):443-451

Bronchodilation by pituitary adenylate cyclase-activating peptide and related peptides

Lindén A; Cardell LO; Yoshihara S; Nadel JA
Review: PULMONARY PHARMACOLOGY & THERAPEUTICS. 1999;12(4):229-236

PACAPs -: Potential for bronchodilation

Lindén A
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1996;805:536-542

A novel PACAP 1-27 analogue causes sustained smooth muscle relaxation in guinea-pig trachea

Yoshihara S; Linden A; Kashimoto K; Nagano Y; Ichimura T; Nadel JA
Review: GENERAL PHARMACOLOGY: THE VASCULAR SYSTEM. 1996;27(7):1109-1121

NANC neural control of airway smooth muscle tone

Linden A
Review: LUNG. 1996;174(1):1-22

Pharmacological basis for duration of effect: Formoterol and salmeterol versus short-acting beta(2)-adrenoceptor agonists

Linden A; Rabe KF; Lofdahl CG
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