Ali Mahdi

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: CARDIOVASCULAR RESEARCH. 2026;122:cvag092.149
Myeloperoxidase delivered by erythrocyte-derived extracellular vesicles promotes oxidative stress and endothelial dysfunction in type 2 diabetes
Collado A; Kontidou E; Santana-Garrido A; Yang J; Mahdi A; Humoud R; Manickam K; Jiao T; Alvarsson M; Pernow J; Zhou Z
Journal article: CARDIOVASCULAR RESEARCH. 2026;122:cvag092.135
Red blood cells and their extracellular vesicles drive vascular endothelial dysfunction in type 2 diabetes through vascular VEGFR2
Jiao T; Collado A; Humoud R; Kontidou E; Santana-Garrido A; Yang J; Mahdi A; Zhou Z
Article: JACC: ADVANCES. 2026;5(5):102702
Post-COVID Postural Orthostatic Tachycardia Syndrome and Inappropriate Sinus Tachycardia: Prevalence, Overlap, and Clinical Characteristics
Juszczyk M; Nawaz S; Mahdi A; Lewinter C; Ricci F; Stahlberg M; Fedorowski A
Journal article: GASTROENTEROLOGY. 2026;170(6):s-1015-s-1016
Sa1624 INCREASED RISK OF ADVERSE ARRHYTHMIA OUTCOMES AFTER ABLATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A NATIONWIDE MATCHED COHORT STUDY
Ebrahimi R; Chen S; Di Vece D; Maremmani M; Mahdi A; Shahim B; Niess JH; Kutz A; Ebrahimi F; Forss A
Journal article: GASTROINTESTINAL ENDOSCOPY. 2026;103(5):s-1015-s-1016
Sa1624 INCREASED RISK OF ADVERSE ARRHYTHMIA OUTCOMES AFTER ABLATION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A NATIONWIDE MATCHED COHORT STUDY
Ebrahimi R; Chen S; Di Vece D; Maremmani M; Mahdi A; Shahim B; Niess JH; Kutz A; Ebrahimi F; Forss A
Article: DIABETES. 2026;75(3):563-570
Long Duration of Type 2 Diabetes Drives Erythrocyte-Induced Vascular Endothelial Dysfunction: A Link to miRNA-210-3p
Kontidou E; Collado A; Humoud R; Manickam K; Tengbom J; Jiao T; Alvarsson M; Yang J; Mellbin L; Mahdi A; Pernow J; Zhou Z
Article: PHYSIOLOGICAL REPORTS. 2026;14(4):e70789
microRNA-210 in red blood cells differentially regulates vascular endothelial function between type 1 and type 2 diabetes
Jiao T; Tengbom J; Kontidou E; Santana-Garrido A; Humoud R; Alvarsson M; Manickam K; Yang J; Mahdi A; Collado A; Pernow J; Zhou Z
Article: ANTIOXIDANTS. 2026;15(1):58
Targeting Arginase 1 but Not Arginase 2 Protects from Myocardial Ischemia-Reperfusion Injury via Nitric Oxide Signaling by Red Blood Cells in Type 2 Diabetes
Yang J; Tratsiakovich Y; Cao R; Mahdi A; Pironti G; Jiao T; Humoud R; Kontidou E; Tengbom J; Collado A; Zhou Z; Cao Y; Kohler E; Mullick AE; Pernow J
Article: CELL REPORTS MEDICINE. 2025;6(11):102454
Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring
Zhao A; Wei Y; Kontidou E; Mahdi A; Jannig PR; Torstensson S; Jiang H; Larsson A; Collado A; Humoud R; Grunler J; Ersga D; Esen BO; Zheng X; Lu H; Lindgren E; Risal S; Zhao J; Stener-Victorin E; Sorensen HT; Pedersen L; Pernow J; Zhou Z; Carlsson S; Catrina S-B; Deng Q
Journal article: EUROPEAN HEART JOURNAL. 2025;46
Cardiac reverse remodeling induced by cardiac resynchronization therapy results in distinct changes in myocardial work when compared to guideline directed medical therapy
Ljung K; Reistam U; Soderstrom L; Gaylard B; Fischer K; Mahdi A; Stahlberg M
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2025;61(12):1904-1912
Increased Risk of Cardiovascular Events After Coronary Interventions in Inflammatory Bowel Disease: A Nationwide Matched Cohort Study
Ebrahimi R; Ebrahimi F; Niess JH; Mahdi A; Chen S; Di Vece D; Bian W; Kutz A; Forss A
Article: AMERICAN JOURNAL OF MEDICINE. 2025;138(6):1019-1028
Post-Acute COVID-19 Syndrome: Prevalence of Peripheral Microvascular Endothelial Dysfunction and Associations With NT-ProBNP Dynamics
Stahlberg M; Fischer K; Tahhan M; Zhao A; Fedorowski A; Runold M; Nygren-Bonnier M; Bjornson M; Lund LH; Bruchfeld J; Desta L; Braunschweig F; Mahdi A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2025;135(10):e180900
Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes
Collado A; Humoud R; Kontidou E; Eldh M; Swaich J; Zhao A; Yang J; Jiao T; Domingo E; Carlestal E; Mahdi A; Tengbom J; Vegvari A; Deng Q; Alvarsson M; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(Suppl_1):atu0045
Abstract Tu0045: Long Duration of Type 2 Diabetes Promotes Erythrocyte-Induced Endothelial Dysfunction: Role of microRNA-210
Kontidou E; Collado A; Humoud R; Manickam K; Jiao T; Alvarsson M; Yang J; Mahdi A; Pernow J; Zhichao Z
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2025;45(Suppl_1):atu0046a
Abstract Tu0046a: Red Blood Cell-Derived Extracellular Vesicles in Type 2 Diabetes Induce Endothelial Dysfunction Through Transfer of Arginase-1 to the Endothelium
Collado A; Humoud R; Kontidou E; Yang J; Mahdi A; Tengbom J; Zhichao Z; Pernow J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2025;182(2):417-431
miR-210 as a therapeutic target in diabetes-associated endothelial dysfunction
Collado A; Jiao T; Kontidou E; Carvalho LRRA; Chernogubova E; Yang J; Zaccagnini G; Zhao A; Tengbom J; Zheng X; Rethi B; Alvarsson M; Catrina S-B; Mahdi A; Carlstroem M; Martelli F; Pernow J; Zhou Z
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2024;327(6):H1431-H1441
Red blood cells from patients with ST-elevation myocardial infarction and elevated C-reactive protein levels induce endothelial dysfunction
Tengbom J; Humoud R; Kontidou E; Jiao T; Yang J; Hedin U; Zhou Z; Jurga J; Collado A; Mahdi A; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2024;45:ehae666.3685
Increased endothelial cell uptake of erythrocyte-derived extracellular vesicles carrying arginase-1 induces endothelial dysfunction in type 2 diabetes
Collado A; Humoud R; Kontidou E; Swaich J; Yang J; Mahdi A; Tengbom J; Zhou Z; Pernow J
Article: CLINICAL SCIENCE. 2024;138(15):975-985
Differences in endothelial function between patients with Type 1 and Type 2 diabetes: effects of red blood cells and arginase
Tengbom J; Kontidou E; Collado A; Yang J; Alvarsson M; Brinck J; Rossner S; Zhou Z; Pernow J; Mahdi A
Journal article: CARDIOVASCULAR RESEARCH. 2024;120:cvae088.035
Red blood cell-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through a mechanism involving arginase 1
Collado A; Humoud R; Kontidou E; Eldh M; Yang J; Jiao T; Domingo E; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Visa fler

Alla övriga publikationer

Meeting abstract: EUROPEAN HEART JOURNAL. 2025;46
Post-COVID postural orthostatic tachycardia syndrome and inappropriate sinus tachycardia: prevalence, overlap and clinical characteristics
Juszczyk M; Nawaz S; Mahdi A; Lewinter C; Ricci F; Stahlberg M; Fedorowski A
Conference publication: EUROPEAN HEART JOURNAL. 2025;46
Differentiation between arginase 1 and 2 in regulating tolerance to cardiac ischemia-reperfusion via nitric oxide signaling by red blood cells
Yang JN; Tratsiakovich Y; Cao RH; Jiao T; Humoud R; Kontidou E; Tengbom J; Collado A; Mahdi A; Zhou Z; Cao YH; Kohler E; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2025;46
Resynchronization reduces arginase activity in red blood cells of heart failure patients with dyssynchrony
Ljung K; Mahdi A; Reistam U; Fischer K; Olsson A; Stahlberg M
Conference publication: EUROPEAN HEART JOURNAL. 2025;46
Endothelial dysfunction in HFrEF: investigating the role of red blood cells and guideline directed medical therapy
Reistam U; Mahdi A; Ljung K; Fischer K; Olsson A; Stahlberg M
Review: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2024;35(3):608-617
Cardiovascular dysautonomia in postacute sequelae of SARS-CoV-2 infection
Stahlberg M; Mahdi A; Johansson M; Fedorowski A; Olshansky B
Meeting abstract: CIRCULATION. 2023;148:a16646
Evidence of Protein Dysregulation in Patients With Post-Acute COVID-19 Syndrome With- and Without Postural Orthostatic Tachycardia Syndrome
Zhao A; Mahdi A; Fredengren E; Fedorowski A; Braunschweig F; Brodin P; Nygren-Bonnier M; Runold M; Bruchfeld J
Letter: CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY. 2023;16(7):413-414
Microvasular Dysfunction and Reduced Cardiac Stress Reactivity in Postural Orthostatic Tachycardia Associated With Postacute COVID-19
Mahdi A; Lodin K; Reistam U; Fedorowski A; Nygren-Bonnier M; Runold M; Bruchfeld J; Desta L; Pernow J; Nickander J; Stahlberg M
Conference publication: GASTROENTEROLOGY. 2023;164(6):S427
PATIENTS WITH MICROSCOPIC COLITIS ARE AT INCREASED RISK OF INCIDENT MAJOR ADVERSE CARDIOVASCULAR EVENTS: A NATIONWIDE HISTOPATHOLOGY MATCHED COHORT STUDY
Forss A; Bergman D; Roelstraete B; Sundstrom J; Mahdi A; Khalili H; Ludvigsson JF
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2917
Red blood cells induce endothelial dysfunction in patients with ST-elevation myocardial infarction and elevated C-reactive protein
Tengbom J; Collado A; Jiao T; Yang J; Zhou Z; Mahdi A; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2910
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection via the purinergic P2Y13 receptor and nitric oxide signalling
Jiao T; Mahdi A; Tengbom J; Collado A; Jurga J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Doctoral thesis: 2021
The red blood cell as a mediator of vascular dysfunction in type 2 diabetes and COVID-19
Mahdi AJ
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3259
Attenuated cardiac post-ischemic injury and endothelial dysfunction by stimulation of soluble guanylyl cyclase in red blood cells from patients with type 2 diabetes
Jiao T; Zhou Z; Mahdi A; Tengbom J; Tratsiakovich Y; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3364
Erythrocytes induce vascular dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:1205
Remote ischemic conditioning fails to protect against ischemia-reperfusion injury in patients with untreated familial hypercholesterolemia
Kovamees O; Mahdi A; Wodaje T; Verouhis D; Brinck J; Pernow J
Editorial: DRUG DISCOVERY TODAY. 2021;26(8):1773-1775
Sunitinib and its effect in the cardiovascular system
Mahdi A; Wernly B; Pernow J; Zhou Z
Review: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;301:207-214
Improvement in endothelial function in cardiovascular disease - Is arginase the target?
Mahdi A; Kovamees O; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:3903
Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells
Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Review: CARDIOVASCULAR RESEARCH. 2019;115(11):1596-1605
Red blood cell dysfunction: a new player in cardiovascular disease
Pernow J; Mahdi A; Yang J; Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2018;39:522-523
Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose lowering therapy
Mahdi A; Kovamees O; Von Heijne M; Alvarsson M; Pernow J
Conference publication: CARDIOVASCULAR RESEARCH. 2018;114:S42
Vascular endothelial growth factor receptor 2 inhibition improves endothelial function in type 2 diabetic rats: a link to purinergic signalling?
Mahdi A; Tratsiakovich Y; Yang J; Ostenson C-G; Danser JAH; Pernow J; Zhou Z
Visa fler

Forskningsbidrag

Koronar mikrovaskulär dysfunktion: Identifiering av sjukdomsmekanismer och nya terapeutiska mål [Translated from English by AI.]
Svenska Läkaresällskapet
18 april 2025
Mikrovaskulär dysfunktion: kliniska utfall, identifiering av sjukdomsmekanismer och nya terapeutiska mål [Translated from English by AI.]
Hjärt-Lungfonden
1 januari 2025 - 1 januari 2026
Är post covid en autoimmun sjukdom? En heltäckande translationell studie inriktad mot snabb implementering av behandling
Region Stockholm (ALF Medicin)
20 december 2023
Koronar mikrovaskulär dysfunktion: identifiering av sjukdomsmekanismer och nya terapeutiska mål. [Translated from English by AI.]
Region Stockholm (Kliniska postdoktorer)
21 juni 2023
Betydelsen av erytrocytdysfunktion för utveckling av hjärtkärlsjukdom vid typ 2-diabetes och som mål för nya behandlingar.
Region Stockholm (ALF Medicin)
25 januari 2023
The importance of microvascular endothelial dysfunction for acute and long-term complications of COVID-19: clinical and mechanistic insights
Swedish Heart-Lung Foundation
1 januari 2021 - 31 december 2021
The importance of vascular and red blood cell arginase for cardiovascular perturbations in diabetes, obesity and hyperlipidemia.
Swedish Heart-Lung Foundation
1 januari 2020 - 31 december 2021
Strategiskt forskningsprogram (SRP) i diabetes

Anställningar

Anknuten till Forskning, Medicin, Solna, Karolinska Institutet, 2025-2028

Examina och utbildning

Medicine Doktorsexamen, Institutionen för medicin, Solna, Karolinska Institutet, 2021
Läkarexamen, Karolinska Institutet, 2019

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI