Mechanisms of establishment of blood vessels – Lars Holmgren's Group

We focuse our efforts into understanding the mechanisms by which blood vessels are established.

Our research

Our research niche is the discovery of the angiomotin family of proteins that play distinct roles during de novo vascularization. Recently, we have also provided evidence that the Amot family plays an important role during tumorigenesis as well. Our overall goal is to understand the molecular pathways involved in the formation of functional vessels and other tube forming organs and to target these pathways in cancer.

Staff and contact

Group leader

  • Professor in Tumor Biology and Director of SFO SciLifeLab at Karolinska Institutet. Research on vascular mechanosensing, AmotL2 and tumor invasion.

All members of the group

Team